Hill et al 2000, developmentally modulated cluster, 195 genes

Gene list file name:Hill2000_T1_cluster6-4.txt
Type of gene identifier:Affymetrix custom chip
Description:Hill et al 2000, Supplymental Dataset, developmentally modulated genes cluster(6,4)  
Organism:Caenorhabditis elegans (nematode)
Gene list type:Experimental

Gene name             Source Gene ID          Annotation                                                  Date       Added by    

AFF_T03D3.9 Aff_T03D3.9 P W
AFF_Y105E8A.H Aff_Y105E8A.H P W
AFF_Y37E11A_93.B Aff_Y37E11A_93.B P W
AFF_Y38A10A.B Aff_Y38A10A.B P W
AFF_Y4C6A.D Aff_Y4C6A.D P W
B0025.4 Aff_B0025.2 P W All gene names: B0025.4; 1G605; CE30120; WBGene00015001; WP:CE30120
B0250.9 Aff_B0250.9 P W All gene names: B0250.9; 5U950; CE36579; WBGene00007126; WP:CE36579 WormBase description: B0250.9 is orthologous to the human gene 7-DEHYDROCHOLESTEROL REDUCTASE (DHCR7; OMIM:602858), which when mutated leads to disease. WormBase CDS description: sterol reductase
                                              
Member of lists (Publications lists):
                                              Lund et al 2002  Fig1 aging-regulated                             
                                              genes, McCarroll et al 2004  SFig5 conserved w/ yeast                              

B0304.1 Aff_B0304.1 P W All gene names: hlh-1; B0304.1; 2E811; CE02423; CE30067; CE31766; MyoD1; WBGene00001948; WP:CE02423; WP:CE30067; WP:CE31766 WormBase description: hlh-1 encodes a basic helix-loop-helix (bHLH) transcription factor that is the sole C. elegans member of the myogenic regulatory factor (MRF) subgroup of bHLH proteins; in C. elegans, HLH-1 activity is required during embryonic development for the proper differentiation and function of body wall muscle cells, indicating that unlike its vertebrate counterparts, hlh-1 is not absolutely required for body wall muscle specification; however, ectopic expression of hlh-1 in the embryo is sufficient to convert nearly all embryonic cell types to a muscle-like fate; in regulating body wall muscle cell development in some cell lineages, hlh-1 likely lies downstream of the PAL-1 homeodomain protein that is required for specification of the C and D founder cell fates; HLH-1 is expressed in nuclei and first appears in body wall muscle precursors beginning at the ~80-cell stage of embryogenesis; expression then continues in these cells and their differentiated descendants throughout embryonic, larval, and adult stages of development. WormBase CDS description: helix-loop-helix transcription factor
                                              
Member of lists (Publications lists):
                                              Baugh et al 2005, validated PAL-1                                 
                                              target genes, Baugh et al 2005, PAL-1 target genes,                                
                                              McCarroll et al 2004  SFig1-4 conserved w/ Drosoph, Roy                            
                                              et al 2002  S2 positivecontrol L1 muscle, ViswanathanM                             
                                              et al 2005  S2 sir-2.1 regulated                                                   

C01B7.1 Aff_C01B7.1 P W All gene names: C01B7.1; C01B7.1a.1; C01B7.1a.2; 5J271; CE29553; CE30719; WBGene00015274; WP:CE29553; WP:CE30719 WormBase description: zinc finger protein
                                              
Member of lists (Publications lists):
                                              Murphy et al 2003  Fig2 Class2 shorten                            
                                              lifespan                                                                           

C01G6.8 Aff_C01G6.8 P W All gene names: cam-1; kin-8; C01G6.8; 2J586; CE24774; CE32563; CE39126; WBGene00000289; WP:CE24774; WP:CE32563; WP:CE39126 WormBase description: The cam-1 gene encodes a receptor tyrosine kinase of the immunoglobulin superfamily that is orthologous to human ROR1 (OMIM:602336) and ROR2 (OMIM:602337, mutation of which leads to type B brachydactyly) and is required for locomotion, cell migration, asymmetric cell division, axon outgrowth, and dauer formation; CAM-1 is broadly expressed during embryogenesis and larval development with expression first appearing at the 200-cell stage of embryogenesis.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, mixed oogenesis soma,                                    
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated,                                     
                                              ViswanathanM et al 2005  S2 daf-16 Resveratrol                                     

C01G8.9 Aff_C01G8.7 P W All gene names: C01G8.9; 1F870; CE30415; CE33359; WBGene00015314; WP:CE30415; WP:CE33359
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, mixed oogenesis soma                                     

C04C11.2 Aff_C04C11.2 P W All gene names: C04C11.2; C04C11.2.1; C04C11.2.2; CE05210; WBGene00007296; WP:CE05210; XO655
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order, Reinke et al 2004, list of genes in                                 
                                              cluster B                                                                          

C06B8.7 Aff_C06B8.7 P W All gene names: C06B8.7; 5P989; CE30854; WBGene00007372; WP:CE30854 WormBase description: Human M130 antigen like protein
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Romagnolo et al 2002  Fig3b                                  
                                              Unkown, ViswanathanM et al 2005  S2 sir-2.1 regulated                              

C06C3.1 Aff_C06C3.1 P W All gene names: mel-11; C06C3.1; 2J657; CE20486; CE32566; CE32567; CE36682; NM_063593; WBGene00003196; WP:CE20486; WP:CE32566; WP:CE32567; WP:CE36682 WormBase description: ankyrin-like repeats
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster F, Reinke et al 2004, list of genes in                                  
                                              cluster order                                                                      

C09D8.1 Aff_C09D8.1 P W All gene names: ptp-3; ptp-3A; ptp-3B; ypp-1; C09D8.1; 2L301; CE30244; CE30245; CE32793; WBGene00004215; WP:CE30244; WP:CE30245; WP:CE32793; YPP/1 WormBase description: ptp-3 encodes a receptor-like tyrosine phosphatase orthologous to the LAR (Leukocyte Common Antigen Related, OMIM:179590) subfamily of receptor-like tyrosine phosphatases that contain extracellular immunoglobulin-like and fibronectin type III domains and have been implicated in linking cell adhesion to intracellular phosphotyrosine levels; PTP-3 plays a role in gastrulation and epidermal development and functions partly redundantly with the VAB-1 Eph receptor and ephrins VAB-2 and EFN-4 to regulate embryonic morphogenesis; PTP-3 is expressed in many tissues during early embryogenesis, but expression later becomes localized to neuronal processes and epithelial adherens junctions.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Romagnolo et al 2002  Fig3b                                  
                                              signaling, ViswanathanM et al 2005  S2 sir-2.1                                     
                                              regulated                                                                          

C09H6.1 Aff_C09H6.1 P W All gene names: spr-4; C09H6.1; 1I685; CE15609; CE30487; WBGene00005009; WP:CE15609; WP:CE30487 WormBase description: Zinc finger, C2H2 type (11 domains)
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order, ViswanathanM et al 2005  S2 sir-2.1                                 
                                              regulated                                                                          

C09H6.2 Aff_C09H6.2 P W All gene names: lin-10; C09H6.2; 1I686; CE15610; CE27060; NM_059825; WBGene00002999; WP:CE15610; WP:CE27060 WormBase description: The lin-10 gene encodes a PDZ and PTB domain-containing protein that is homologous to mammalian Munc interacting proteins (Mint1, OMIM:602414) and is required for polarized protein localization; LIN-10 is required for proper localization of the LET-23 EGF receptor to the basolateral membrane of the vulval precursor cells and for proper postsynaptic localization of GLR-1, an AMPA-type glutamate receptor in interneurons; LIN-10 is detected in the cytoplasm, membrane, and at particularly high levels in the Golgi. WormBase CDS description: Phosphotyrosine interaction domain (PTB/PID)., PDZ domain (Also known as DHR or GLGF). (2 domains)
C13F10.2 Aff_C13F10.2 P W All gene names: C13F10.2; 5H703; CE08144; WBGene00015742; WP:CE08144
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt herm vs wt male enriched gen, Reinke et al                             
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated                                                         

C17G1.4 Aff_C17G1.4 P W All gene names: C17G1.4; CE08283; CE37318; WBGene00007651; WP:CE08283; WP:CE37318; XK546
                                              
Member of lists (Publications lists):
                                              Murphy et al 2003  Fig2 Class1                                    
                                              elongate lifespan, Reinke et al 2004, fem1 enriched                                
                                              genes, Reinke et al 2004, mixed oogenesis soma, Reinke                             
                                              et al 2004, GO categories                                                          

C17H11.6 Aff_C17H11.6 P W All gene names: C17H11.6; C17H11.6c.1; C17H11.6c.2; C17H11.6c.3; CE27704; CE27705; CE33601; WBGene00015926; WP:CE27704; WP:CE27705; WP:CE33601; XI804
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

C26E6.2 Aff_C26E6.2 P W All gene names: C26E6.2; 3G43; CE32143; WBGene00016138; WP:CE32143
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, list of genes in cluster                                 
                                              order, Reinke et al 2004, mixed oogenesis soma, Reinke                             
                                              et al 2004, list of genes in cluster E, ViswanathanM et                            
                                              al 2005  S2 sir-2.1 regulated, ViswanathanM et al 2005                             
                                              S2 daf-16 Resveratrol                                                              

C29A12.3 Aff_C29A12.3 P W All gene names: lig-1; C29A12.3; 5L295; CE37480; CE37481; NM_171537; NM_171538; WBGene00002985; WP:CE37480; WP:CE37481 WormBase description: lig-1 is orthologous to the human gene LIM HOMEOBOX PROTEIN 3 ISOFORM B (LIG1; OMIM:600577), which when mutated leads to disease.
                                              
Member of lists (Publications lists):
                                              Lund et al 2002  Fig3D Oocyte-en,                                 
                                              McCarroll et al 2004  SFig5 conserved w/ yeast,                                    
                                              McCarroll et al 2004  SFig1-4 conserved w/ Drosoph,                                
                                              Reinke et al 2004, fem1 enriched genes, Reinke et al                               
                                              2004, oogenesis enriched genes, Reinke et al 2004, wt                              
                                              vs glp-4 enriched genes, Reinke et al 2004, wt herm vs                             
                                              wt male enriched gen, ViswanathanM et al 2005  S2                                  
                                              daf-16 Resveratrol, ViswanathanM et al 2005  S2 sir-2.1                            
                                              regulated                                                                          

C29F9.7 Aff_C29F9.7 P W All gene names: pat-4; C29F9.7; C29F9.7.1; C29F9.7.2; 3A708; CE19706; NM_064738; WBGene00003931; WP:CE19706 WormBase description: The pat-4 gene encodes a serine/threonine kinase orthologous to human integrin-linked kinase (ILK, OMIM:602366) and is required for formation of integrin-mediated muscle cell attachments during embryogenesis; PAT-4 probably functions as an adaptor molecule and localizes to dense bodies and M lines; PAT-4 forms a ternary complex with PAT-6/actopaxin and UNC-112, and requires UNC-112, UNC-52/perlecan, PAT-2/alpha integrin, and PAT-3/beta integrin for proper localization to newly forming integrin adhesion complexes. WormBase CDS description: integrin-linked kinase
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster order, Reinke et al 2004, list of genes in                              
                                              cluster C, Roy et al 2002  S2 positivecontrol L1 muscle                            

C31E10.5 Aff_C31E10.5 P W All gene names: C31E10.5; CE08505; WBGene00007846; WP:CE08505; XO610
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, wt herm vs wt male enriched                              
                                              gen, Reinke et al 2004, mixed oogenesis soma, Romagnolo                            
                                              et al 2002  Fig3b Unkown, ViswanathanM et al 2005  S2                              
                                              sir-2.1 regulated, ViswanathanM et al 2005  S2 daf-16                              
                                              Resveratrol                                                                        

C33B4.3 Aff_C33B4.3 P W All gene names: tag-67; C33B4.3; 2L676; CE01508; CE36107; WBGene00006444; WP:CE01508; WP:CE36107 WormBase description: ankyrin and proline rich domains
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, ViswanathanM et al 2005  S2                                  
                                              sir-2.1 regulated                                                                  

C34E10.7 Aff_C34E10.7 P W All gene names: cnd-1; hlh-5; C34E10.7; 3G328; CE01187; NM_065714; WBGene00000561; WP:CE01187 WormBase description: cnd-1 is orthologous to the human gene NEUROGENIC DIFFERENTIATION 1 (NEUROD1; OMIM:601724), which when mutated leads to disease.
C35D10.9 Aff_C35D10.9 P W All gene names: ced-4; C35D10.9; 3F943; CE01203; CE38154; WBGene00000418; WP:CE01203; WP:CE38154 WormBase description: ced-4 encodes a novel protein; along with CED-3, CED-4 is required for the initiation of programmed cell death; accordingly, genetic analyses indicate that ced-3 and ced-4 function upstream of ced-1, ced-2, and nuc-1 in the programmed cell death pathway; in yeast two-hybrid experiments, and upon coexpression in mammalian cells, CED-4 interacts with CED-9, an anti-apoptotic BCL-2 homolog; coexpression of CED-4 and CED-9 results in redistribution of CED-4 from the cytosol to organellar membranes, suggesting that CED-9 may negatively regulate CED-4 activity by sequestering CED-4 to intracellular membranes.
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, list of genes in cluster F, Reinke et al                               
                                              2004, wt vs glp-4 enriched genes, Reinke et al 2004,                               
                                              list of genes in cluster order, Reinke et al 2004, wt                              
                                              herm vs wt male enriched gen, ViswanathanM et al 2005                              
                                              S2 sir-2.1 regulated                                                               

C35E7.1 Aff_C35E7.1 P W All gene names: C35E7.1; 1L423; CE36273; NM_060435; WBGene00016453; WP:CE36273
                                              
Member of lists (Publications lists):
                                              Murphy et al 2003  Fig2 Class2 shorten                            
                                              lifespan, Reinke et al 2004, fem1 enriched genes,                                  
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, mixed oogenesis soma, Reinke et al                              
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated                                                         

C37A2.8 Aff_C37A2.8 P W All gene names: C37A2.8; 1H376; CE08617; CE29218; WBGene00016494; WP:CE08617; WP:CE29218
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, wt herm vs wt male enriched gen, ViswanathanM et                             
                                              al 2005  S2 sir-2.1 regulated                                                      

C45B11.2 Aff_C45B11.2 P W All gene names: C45B11.2; 5L525; CE05426; WBGene00008105; WP:CE05426 WormBase description: epoxide hydrolase like
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated, ViswanathanM et al 2005  S2 daf-16                                      
                                              Resveratrol                                                                        

C48G7.3 Aff_Y50E8A.S P W All gene names: tag-333; C48G7.3; CE23604; WBGene00008183; WP:CE23604
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster F, Reinke et al 2004, list of genes in                                  
                                              cluster order, Reinke et al 2004, wt herm vs wt male                               
                                              enriched gen                                                                       

C50C3.6 Aff_C50C3.6 P W All gene names: prp-8; C50C3.6; 3J261; CE00122; NM_066384; WBGene00004187; WP:CE00122 WormBase description: prp-8 is orthologous to the human gene SIMILAR TO U5 SNRNP-SPECIFIC PROTEIN (220 KD), ORTHOLOG OF S.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, intrinsic, Reinke et al                                
                                              2004, wt vs glp-4 enriched genes                                                   

C50H11.8 Aff_C50H11.8 P W All gene names: C50H11.8; 5D529; CE35258; WBGene00016855; WP:CE35258
                                              
Member of lists (Publications lists):
                                              Wang et al 2003  S4 TransientList,                                
                                              Wang et al 2003  S3  genes pass one-way ANOVA, Wang et                             
                                              al 2003  S4 genes pass two-wayANOVA P0                                             

C52A10.3 Aff_C52A10.3 P W All gene names: C52A10.3; 5F716; CE17584; WBGene00016864; WP:CE17584
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

D1044.2 Aff_D1044.2 P W All gene names: D1044.2; 3G623; CE29243; CE29244; CE39713; WBGene00017028; WP:CE29243; WP:CE29244; WP:CE39713
D1054.13 Aff_D1054.13 P W All gene names: D1054.13; 5L284; CE05531; WBGene00008379; WP:CE05531
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster order, Reinke et al 2004, wt herm vs wt male                            
                                              enriched gen, Reinke et al 2004, list of genes in                                  
                                              cluster E, ViswanathanM et al 2005  S2 sir-2.1                                     
                                              regulated                                                                          

D1069.2 Aff_D1069.2 P W All gene names: cpn-2; D1069.2; D1069.2.1; D1069.2.2; 2A629; CE38495; NM_061312; WBGene00000778; WP:CE38495 WormBase description: cpn-2 encodes a calponin homolog, more similar to the calponin paralogs transgelin (SM22 alpha) or neuronal protein NP25 than to calponin per se. WormBase CDS description: calponin
                                              
Member of lists (Publications lists):
                                              Romagnolo et al 2002  Fig3b Cell                                  
                                              Structure, ViswanathanM et al 2005  S2 daf-16                                      
                                              Resveratrol, Wang et al 2003  S3  genes pass one-way                               
                                              ANOVA, Wang et al 2003  S4 LateList, Wang et al 2003                               
                                              S4 genes pass two-wayANOVA P0                                                      

D2045.6 Aff_D2045.6 P W All gene names: cul-1; lin-19; D2045.6; 3L563; CE29089; WBGene00000836; WP:CE29089 WormBase description: cul-1 encodes a cullin, orthologous to Cdc53/Cul1 in S. cerevisiae and CUL-1 in humans (OMIM:603134), that is required both maternally and zygotically for developmentally programmed transitions from the G1 phase of the cell cycle to the GO phase or the apoptotic pathway, and that is probably also required for normally slow G1-to-S phase progression; CUL-1 physically interacts with eight Skp1-related proteins (SKR-1, -2, -3, -4, -7, -8, -9, and -10). WormBase CDS description: Cuticlin family
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Murphy et al 2003  Fig2 Class2 shorten                                    
                                              lifespan                                                                           

D2092.2 Aff_D2092.2 P W All gene names: D2092.2; D2092.2.1; D2092.2.2; 1H202; CE09101; WBGene00017064; WP:CE09101
                                              
Member of lists (Publications lists):
                                              Lund et al 2002   Fig3C                                           
                                              Germline-intrinsic, Reinke et al 2004, list of genes in                            
                                              cluster F, Reinke et al 2004, fem1 enriched genes,                                 
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt vs glp-4 enriched genes, Reinke et al 2004,                            
                                              wt herm vs wt male enriched gen, ViswanathanM et al                                
                                              2005  S2 sir-2.1 regulated                                                         

F01F1.15 Aff_F01F1.11 P W All gene names: F01F1.15; F01F1.15.1; F01F1.15.2; 3G958; CE26884; WBGene00017169; WP:CE26884
F02G3.1 Aff_F02G3.1 P W All gene names: ncam-1; F02G3.1; CE30933; CE30934; CE30935; NM_171615; WBGene00017184; WP:CE30933; WP:CE30934; WP:CE30935; XB321 WormBase description: neural cell adhesion molecule
                                              
Member of lists (Publications lists):
                                              Murphy et al 2003  Fig2 Class2 shorten                            
                                              lifespan, ViswanathanM et al 2005  S2 daf-16                                       
                                              Resveratrol                                                                        

F09F3.4 Aff_F09F3.4 P W All gene names: srx-133; F09F3.4; 5O325; CE36289; NM_074030; WBGene00006024; WP:CE36289 WormBase description: 7TM receptor, srx family
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

F10E9.6 Aff_F10E9.6 P W All gene names: mig-10; F10E9.6; F10E9.6a.1; F10E9.6a.2; 3J395; CE00150; CE29261; CE36129; NM_066420; NM_066421; WBGene00003243; WP:CE00150; WP:CE29261; WP:CE36129 WormBase description: mig-10 encodes a protein containing a pleckstrin homology domain and a proline-rich region, and is similar to the SH2-domain containing adapter proteins Grb7 and Grb10 which are involved in receptor tyrosine kinase-mediated signal transduction; MIG-10 is likely required for signal transduction during cell migration, as it is required non-cell autonomously for excretory canal development and anterior-posterior migrations of the embryonic neurons ALM, CAN, and HSN; mig-10 mutations appear to interact genetically with mutations in all three C. elegans rac genes, ced-10, mig-2, and rac-2, suggesting partial redundancy during neuronal migration and excretory canal outgrowth; MIG-10 is expressed in many embryonic cells and in four cells in the adult head.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph                                                               

F10E9.8 Aff_F10E9.8 P W All gene names: dcd-1; sas-4; F10E9.8; 3J404; CE29756; NM_066427; WBGene00004726; WP:CE29756 WormBase description: sas-4 encodes a predicted coiled-coil protein and centriole component recruited to the centrosome once per cell cycle at the time of organelle duplication and is required for centriole duplication and spindle assembly, levels dictate centrosome size, and also affects germ cell proliferation and locomotion; colocalizes with gamma-tubulin to centrosomes both in sperm and in the syncitial part of the gonad.
                                              
Member of lists (Publications lists):
                                              Lund et al 2002  Fig1 aging-regulated                             
                                              genes, Reinke et al 2004, list of genes in cluster F,                              
                                              Reinke et al 2004, fem1 enriched genes, Reinke et al                               
                                              2004, wt vs glp-4 enriched genes, Reinke et al 2004,                               
                                              list of genes in cluster order, Reinke et al 2004,                                 
                                              oogenesis enriched genes, Reinke et al 2004, wt herm vs                            
                                              wt male enriched gen                                                               

F11D5.3 Aff_F11D5.3 P W All gene names: F11D5.3; F11D5.3b.1; F11D5.3b.2; F11D5.3b.3; CE27950; CE27951; WBGene00017381; WP:CE27950; WP:CE27951; XD941 WormBase description: F11D5.3 encodes a putative tyrosine kinase homologous to human RS1 (OMIM:312700, mutated in juvenile X-linked retinoschisis).
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, ViswanathanM et al 2005  S2                                  
                                              daf-16 Resveratrol                                                                 

F14B4.1 Aff_F14B4.1 P W All gene names: F14B4.1; 1J842; CE38950; WBGene00008779; WP:CE38950 WormBase description: LDL receptor-related protein
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order                                                                      

F14D12.2 Aff_F14D12.2 P W All gene names: unc-97; F14D12.2; CE04392; NM_076542; WBGene00006826; WP:CE04392; XG213 WormBase description: The unc-97 gene encodes a LIM domain-containing protein of the PINCH family that is highly similar to human LIMS1 (OMIM:602567) and LIMS2; UNC-97 functions as an adaptor protein important for assembly of muscle adherens junctions and the mechanosensory functions of the touch neurons; UNC-97 interacts with PAT-4/integrin-linked kinase and with UNC-98; UNC-97 colocalizes with PAT-3/beta integrin at dense bodies, focal adhesion-like muscle attachment structures. WormBase CDS description: LIM domain containing protein
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster A, Reinke et al 2004, list of genes in                                  
                                              cluster order                                                                      

F14H3.3 Aff_F14H3.3 P W All gene names: F14H3.3; 5Q532; CE23651; WBGene00008822; WP:CE23651
                                              
Member of lists (Publications lists):
                                              Golden et al 2004, daf-2                                          
                                              differentially expressed , Reinke et al 2004,                                      
                                              intrinsic, Reinke et al 2004, wt vs glp-4 enriched                                 
                                              genes, Reinke et al 2004, list of genes in cluster                                 
                                              order, Reinke et al 2004, wt herm vs wt male enriched                              
                                              gen, Reinke et al 2004, list of genes in cluster E,                                
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

F18E9.5 Aff_F18E9.5 P W All gene names: tag-279; F18E9.5; CE30957; CE30958; WBGene00017571; WP:CE30957; WP:CE30958; XJ193
                                              
Member of lists (Publications lists):
                                              Murphy et al 2003  Fig2 Class2 shorten                            
                                              lifespan                                                                           

F21A10.2 Aff_F21A10.2 P W All gene names: F21A10.2; F21A10.2a.1; F21A10.2a.2; F21A10.2a.3; F21A10.2a.4; CE23678; CE31488; CE31489; WBGene00008999; WP:CE23678; WP:CE31488; WP:CE31489; XK800
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster A, Reinke et al 2004, list of genes in cluster                             
                                              order                                                                              

F21H11.3 Aff_F21H11.3 P W All gene names: sdf-13; tbx-2; F21H11.3; F21H11.3.1; F21H11.3.2; 3G222; CE01245; NM_065687; WBGene00006543; WP:CE01245 WormBase description: tbx-2 encodes one of 21 C. elegans T-box transcription factors; during development, tbx-2 activity is required for normal adaptation, but not chemotaxis, to attractive odorants sensed by the AWC amphid neurons; tbx-2 is also required redundantly with unc-3 and unc-31 for negative regulation of dauer formation, and large-scale RNAi screens reveal an essential role for tbx-2 in early larval development, normal rates of postembryonic growth, and locomotory behavior; antibodies to TBX-2 detect expression in the cytoplasm of amphid and pharyngeal neurons in larvae and adults, suggesting that TBX-2 function may be controlled, in part, by regulation of its subcellular localization; in addition, in situ hybridization studies indicate that tbx-2 mRNA is expressed during mid-embryogenesis; tbx-2 expression in the AWC amphid neurons is sufficient to rescue the olfactory adaptation defects seen in tbx-2 mutant animals.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph                                                               

F25B4.2 Aff_F25B4.2 P W All gene names: F25B4.2; 5G191; CE30760; PELLINO; WBGene00017766; WP:CE30760
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, mixed oogenesis soma, Reinke                             
                                              et al 2004, wt herm vs wt male enriched gen,                                       
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated, Wang et                             
                                              al 2003  S4 TransientList, Wang et al 2003  S3  genes                              
                                              pass one-way ANOVA, Wang et al 2003  S4 genes pass                                 
                                              two-wayANOVA P0                                                                    

F25E2.5 Aff_F25E2.5 P W All gene names: daf-3; F25E2.5; CE26364; CE28002; CE30963; NM_075760; WBGene00000899; WP:CE26364; WP:CE28002; WP:CE30963; XB438 WormBase description: daf-3 encodes a Smad protein; DAF-3 functions as a transcriptional regulator that is required for formation of the alternative dauer larval stage; DAF-3 activity is antagonized by signaling through the DAF-7/TGF-beta pathway which promotes reproductive growth; in yeast two-hybrid studies, DAF-3 interacts with SMA-3, another Smad protein that does not appear to have a role in dauer formation; a DAF-3::GFP fusion protein is expressed in many tissues that undergo remodeling during dauer development; DAF-3 localizes predominantly to the cytoplasm, but is also found associated with chromosomes in mitotic cells.
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  T2 lifespan and                                 
                                              Dauer, ViswanathanM et al 2005  S2 daf-16 Resveratrol                              

F27D4.2 Aff_F27D4.2 P W All gene names: F27D4.2; F27D4.2.1; F27D4.2.2; F27D4.2.3; F27D4.2.4; 1I282; CE36140; WBGene00009188; WP:CE36140
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, wt herm vs wt male enriched gen, Reinke et al                                
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated                                                         

F31E3.1 Aff_F31E3.1 P W All gene names: ceh-20; F31E3.1; 3I71; CE01241; WBGene00000443; WP:CE01241 WormBase description: A co-factor homeodomain protein and homolog of Drosophila Extradenticle (Exd) that together with ceh-40 affects embryogenesis, loss of both functions affect embryonic viability; it is required as a cofactor for LIN-39- and MAB-5- dependent postembryonic mesoderm patterning; it genetically interacts with unc-62.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster A, Reinke et al 2004, list of genes in                                  
                                              cluster order, ViswanathanM et al 2005  S2 sir-2.1                                 
                                              regulated                                                                          

F32B6.1 Aff_F32B6.1 P W All gene names: nhr-4; F32B6.1; F32B6.1.1; F32B6.1.2; 4K645; CE24934; NM_069374; WBGene00003603; WP:CE24934 WormBase description: nhr-4 is predicted to encode a nuclear hormone receptor (NHR); expression may peak during the late larval stages, based on mRNA expression analysis. WormBase CDS description: Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains)
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated, ViswanathanM et al 2005  S2 daf-16                                      
                                              Resveratrol, Wang et al 2003  S3  genes pass one-way                               
                                              ANOVA, Wang et al 2003  S4 Dauer Enriched, Wang et al                              
                                              2003  S4 genes pass two-wayANOVA P0                                                

F40D4.13 Aff_F40D4.13 P W All gene names: F40D4.13; 5R632; CE19847; WBGene00009572; WP:CE19847
                                              
Member of lists (Publications lists):
                                              Romagnolo et al 2002  Fig3b Unkown                                

F43D9.1 Aff_F43D9.1 P W All gene names: F43D9.1; 3L589; CE32661; WBGene00009653; WP:CE32661 WormBase description: Band 4.1 domain
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order, Reinke et al 2004, list of genes in                                 
                                              cluster B                                                                          

F44F1.7 Aff_F44F1.7 P W All gene names: vet-6; F44F1.7; 1N863; CE10424; NM_060931; WBGene00006902; WBGene00009699; WP:CE10424 WormBase description: vet-6 encodes a protein that contains a spectrin repeat; vet-6 is preferentially transcribed in embryos prior to gastrulation.
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

F44G4.8 Aff_F44G4.8 P W All gene names: dep-1; F44G4.8; 2J296; CE03335; NM_063524; WBGene00009717; WP:CE03335 WormBase description: protein tyrosine phosphatase
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Dauer specific genes                            
                                              P<0.05, McCarroll et al 2004  SFig1-4 conserved w/                                 
                                              Drosoph, Wang et al 2003  S7 SAGE genes in the dataset,                            
                                              Wang et al 2003  S8 SAGE genes in the dauer exit                                   

F45G2.7 Aff_F45G2.7 P W All gene names: F45G2.7; 3O522; CE16050; WBGene00009733; WP:CE16050
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, list of genes in cluster                                 
                                              order, Reinke et al 2004, mixed oogenesis soma, Reinke                             
                                              et al 2004, list of genes in cluster E, ViswanathanM et                            
                                              al 2005  S2 sir-2.1 regulated                                                      

F46A9.6 Aff_C17E4.11 P W All gene names: mec-8; F46A9.6; F46A9.6.1; F46A9.6.2; F46A9.6.3; 1K18; CE08260; NM_060107; WBGene00003172; WP:CE08260 WormBase description: mecanosensory gene mec-8
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster A, Reinke et al 2004, list of genes in                                  
                                              cluster order, Wang et al 2003  S4 Early genes, Wang et                            
                                              al 2003  S3  genes pass one-way ANOVA, Wang et al 2003                             
                                              S4 genes pass two-wayANOVA P0                                                      

F46F6.2 Aff_F46F6.2 P W All gene names: F46F6.2; CE31703; NM_077341; WBGene00009793; WP:CE31703; XL19 WormBase description: Protein kinase C terminal domain
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Dauer specific genes                            
                                              P<0.05, McCarroll et al 2004  SFig1-4 conserved w/                                 
                                              Drosoph, Wang et al 2003  S7 SAGE genes in the dataset,                            
                                              Wang et al 2003  S8 SAGE genes in the dauer exit                                   

F47D12.4 Aff_F47D12.4 P W All gene names: hmg-1.2; son-1; F47D12.4; 3H371; CE26923; CE28233; CE28234; NM_065974; WBGene00001972; WP:CE26923; WP:CE28233; WP:CE28234
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, wt herm vs wt male enriched                              
                                              gen, Reinke et al 2004, mixed oogenesis soma,                                      
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

F47G4.4 Aff_F47G4.4 P W All gene names: F47G4.4; F47G4.4.1; F47G4.4.2; 1O656; CE18702; WBGene00009825; WP:CE18702 WormBase description: F47G4.4 encodes a paralog of MEI-2 that, like MEI-2, binds MEI-1 in vitro; F47G4.4 might thus be an alternative ligand of MEI-1 in vivo.
F49H12.1 Aff_F49H12.I P W All gene names: lsy-2; F49H12.1; F49H12.1b.1; F49H12.1b.2; CE28437; CE38521; NM_075984; WBGene00003087; WP:CE28437; WP:CE38521; XC711 WormBase description: C2H2-type zinc finger protein
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

F52C9.8 Aff_F52C9.4 P W All gene names: pqe-1; F52C9.8; F52C9.8d.1; F52C9.8d.2; 3G411; CE30672; CE30673; CE30674; CE30675; CE30802; CE30998; CE39256; NM_065734; NM_065735; NM_065736; NM_171119; NM_171120; NM_171864; WBGene00004095; WP:CE30672; WP:CE30673; WP:CE30674; WP:CE30675; WP:CE30802; WP:CE30998; WP:CE39256
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes                                             

F52G3.1 Aff_F52G3.1 P W All gene names: F52G3.1; CE28439; WBGene00018710; WP:CE28439; XR585
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 daf-16                                
                                              Resveratrol                                                                        

F53A2.3 Aff_F53A2.3 P W All gene names: F53A2.3; 3O426; CE16095; WBGene00009951; WP:CE16095
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

F53B2.6 Aff_F53B2.6 P W All gene names: ham-1; F53B2.6; 4N309; CE17851; NM_070000; WBGene00001820; WP:CE17851 WormBase description: ham-1 encodes a novel protein with a winged helix DNA-binding motif; ham-1 is required for the asymmetric divisions of several neuroblasts in the developing embryo and may influence their spindle position; ham-1 mutations also exhibit HSN motor neuron migration defects; HAM-1 interacts with itself in a yeast two-hybrid screen and observations suggest that its multimerization is required for its proper localization; HAM-1 is cytoplasmic and is asymmetrically distributed to the posterior of the HSNPHB neuroblast.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Wang et al 2003  S4 Climbing,                                
                                              Wang et al 2003  S3  genes pass one-way ANOVA, Wang et                             
                                              al 2003  S4 genes pass two-wayANOVA P0                                             

F53C11.7 Aff_F53C11.7 P W All gene names: swan-2; tag-206; F53C11.7; F53C11.7.1; F53C11.7.2; F53C11.7.3; 5O282; CE24997; WBGene00009976; WP:CE24997 WormBase description: Yeast hypothetical protein YPL247C like
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph                                                                            

F53H2.3 Aff_F53H2.3 P W All gene names: F53H2.3; 5U866; CE19888; WBGene00010006; WP:CE19888
F54E7.3 Aff_F54E7.3 P W All gene names: par-3; F54E7.3; 3G765; CE28449; CE28450; CE39941; NM_065816; WBGene00003918; WP:CE28449; WP:CE28450; WP:CE39941 WormBase description: par-3 encodes a PDZ domain-containing protein orthologous to mammalian atypical PKC isotype-specific interacting protein (ASIP) and Drosophila Bazooka; PAR-3 is required maternally for polarization of the zygote along the anterior-posterior (A-P) axis; PAR-3, PAR-6, and PKC-3 form a complex that localizes to the anterior cytoplasmic cortex of the one- and two-cell embryo; this localization is regulated spatially by PAR-2, which segregates to the posterior cortex.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt herm vs wt male enriched gen                                           

F54F2.2 Aff_F54F2.2 P W All gene names: zfp-1; zpf-1; F54F2.2; F54F2.2a.1; F54F2.2a.2; F54F2.2a.3; F54F2.2c.1; F54F2.2c.2; 3J897; CE25003; CE26933; CE33653; WBGene00006975; WP:CE25003; WP:CE26933; WP:CE33653 WormBase description: zfp-1 encodes a leucine zipper, zinc finger, and PHD/LAP domain (plant homeodomain/leukemia-associated protein)-containing protein homologous to human AF10 (OMIM:602409, which is involved in chromosomal translocations associated with acute leukemia); loss of zfp-1 activity via RNA-mediated interference (RNAi) results in suppression of RNAi, suggesting that ZFP-1 plays a role in gene silencing; based on sequence similarity, ZFP-1 is predicted to associate with chromatin.
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, mixed oogenesis soma,                                    
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

F54G8.3 Aff_F54G8.3 P W All gene names: ina-1; F54G8.3; 3K258; CE00205; NM_066631; WBGene00002081; WP:CE00205 WormBase description: Integrin alpha chain
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, ViswanathanM et al 2005  S2                                  
                                              sir-2.1 regulated                                                                  

F55A11.5 Aff_F55A11.5 P W All gene names: acl-10; F55A11.5; 5M255; CE39507; NM_073570; WBGene00010078; WP:CE39507 WormBase description: 1-acyl-glycerol-3-phosphate acyltransferase
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated, ViswanathanM et al 2005  S2 daf-16                                      
                                              Resveratrol                                                                        

F55A8.1 Aff_Y48A5B.B P W All gene names: egl-18; elt-5; pvl-3; F55A8.1; F55A8.1.1; F55A8.1.2; F55A8.1.3; 4C681; CE28339; NM_067742; WBGene00001186; WP:CE28339 WormBase description: egl-18 encodes a member of the GATA-family of transcription factors that affects cell migration, cell fate specification; expressed in the head, in hypodermal seam cells, VC neurons, and vulval precursor cells. WormBase CDS description: zinc finger protein
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, list of genes in cluster                                 
                                              order, Reinke et al 2004, mixed oogenesis soma, Reinke                             
                                              et al 2004, list of genes in cluster E, ViswanathanM et                            
                                              al 2005  S2 sir-2.1 regulated                                                      

F55C9.10 Aff_F55C9.10 P W All gene names: fbxb-61; F55C9.10; 5T775; CE18742; WBGene00010106; WP:CE18742 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
F55C9.4 Aff_F55C9.4 P W All gene names: fbxb-57; F55C9.4; 5T763; CE18736; WBGene00010101; WP:CE18736 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
F55C9.7 Aff_F55C9.7 P W All gene names: fbxb-60; F55C9.7; 5T771; CE18739; WBGene00010104; WP:CE18739 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
F56A8.8 Aff_F56A8.8 P W All gene names: F56A8.8; 3O375; CE16128; WBGene00010142; WP:CE16128
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order, Reinke et al 2004, list of genes in                                 
                                              cluster E, ViswanathanM et al 2005  S2 sir-2.1                                     
                                              regulated, ViswanathanM et al 2005  S2 daf-16                                      
                                              Resveratrol                                                                        

F56D1.4 Aff_F56D1.4 P W All gene names: clr-1; F56D1.4; 2F767; CE32051; CE32052; CE32053; WBGene00000548; WP:CE32051; WP:CE32052; WP:CE32053 WormBase description: A receptor tyrosine phosphatase that negatively regulates the FGF receptorsignaling pathway; it localizes to the plasma membrane.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph                                                               

F56F4.1 Aff_F56F4.1 P W All gene names: sdz-22; F56F4.1; 1G727; CE39020; WBGene00018978; WP:CE39020
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, list of genes in cluster                                 
                                              order, Reinke et al 2004, mixed oogenesis soma, Reinke                             
                                              et al 2004, GO categories, Reinke et al 2004, list of                              
                                              genes in cluster E, ViswanathanM et al 2005  S2 sir-2.1                            
                                              regulated                                                                          

F56H1.3 Aff_C04F1.3 P W All gene names: F56H1.3; 1G306; CE17914; WBGene00018994; WP:CE17914
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, herm sperm, Reinke                             
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, spermatogenesis enriched genes, Reinke et al                                 
                                              2004, fem3 enriched genes, ViswanathanM et al 2005  S2                             
                                              sir-2.1 regulated                                                                  

F58B6.3 Aff_F58B6.3 P W All gene names: par-2; F58B6.3; 3C183; CE25917; CE39258; NM_064931; WBGene00003917; WP:CE25917; WP:CE39258 WormBase description: par-2 encodes a protein containing a C3HC4-type RING-finger, a specialized type of zinc-finger found in E3 ubiquitin ligase subunits; PAR-2 is required maternally for polarization of the C. elegans zygote along the anterior-posterior (A-P) axis and is asymmetrically localized to the posterior cortex of the one- and two-cell embryo via interdependent interactions with PAR-3, PAR-6, and PKC-3.
F58H1.5 Aff_F58H1.5 P W All gene names: F58H1.5; F58H1.5.1; F58H1.5.2; 5M441; CE06029; WBGene00010288; WP:CE06029
F59A6.1 Aff_F59A6.1 P W All gene names: ask-1; esp-8; nsy-1; F59A6.1; 2F319; CE33405; NM_062524; WBGene00003822; WP:CE33405 WormBase description: nsy-1 encodes a MAP kinase kinase kinase homolog that affects chemotaxis, egg laying, and pathogen response; NSY-1 activity is activated by the calmodulin kinase UNC-43, and is required for lateral signalling that leads to asymmetric olfactory neuron fates; interacts with SEK-1, and is expressed in the intestine, hypodermis, rectal gland cells, and neurons. WormBase CDS description: Protein kinase
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph                                                                            

F59D6.1 Aff_F59D6.1 P W All gene names: F59D6.1; 5D527; CE11476; WBGene00019103; WP:CE11476
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

H04J21.3 Aff_H04J21.3 P W All gene names: gip-1; H04J21.3; H04J21.3a.1; H04J21.3a.2; 3D451; CE31849; CE32450; CE34566; CeGrip; NM_065139; WBGene00001589; WP:CE31849; WP:CE32450; WP:CE34566 WormBase description: gip-1 encodes the C. elegans homolog of Saccharomyces cerevisiae Spc98p, a gamma-tubulin-binding protein that with Spc97p forms part of a gamma-tubulin ring complex that can nucleate microtubule formation in vitro and in vivo; in C. elegans, GIP-1 is essential for embryogenesis and required for formation of centrosomal asters during interphase and formation of the mitotic spindle, but not for formation of mitotic asters; GIP-1 colocalizes with TBG-1/gamma-tubulin to centrosomes during interphase and mitosis; GIP-1 and TBG-1 are required reciprocally for centrosomal localization.
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Non dauer genes                                 
                                              P<0.05, ViswanathanM et al 2005  S2 sir-2.1 regulated                              

H12D21.8 Aff_H12D21.8 P W All gene names: H12D21.8; 5P385; CE19921; WBGene00010384; WP:CE19921
H24O09.2 Aff_H24O09.B P W All gene names: fbxb-72; H24O09.2; 5B202; CE23825; WBGene00019243; WP:CE23825
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, male sperm, Reinke                             
                                              et al 2004, list of genes in cluster order, Reinke et                              
                                              al 2004, wt males vs glp4 male enriched , Reinke et al                             
                                              2004, mixed sperm soma, Reinke et al 2004, wt herm vs                              
                                              wt herm enriched gen, Reinke et al 2004, list of genes                             
                                              in cluster D, Reinke et al 2004, fem3 enriched genes                               

K03D10.1 Aff_K03D10.1 P W All gene names: kal-1; K03D10.1; 1O722; CE35892; NM_061067; WBGene00002181; WP:CE35892 WormBase description: kal-1 encodes a cell surface protein that contains a WAP-type protease inhibitor domain and Type III fibronectin domains and is the C. elegans ortholog of human KAL-1, mutated in the X-linked form of the neurological disorder Kallmann syndrome; in C. elegans, both kal-1 loss-of-function mutations and kal-1 overexpression result in similar phenotypes that indicate KAL-1 activity is required for epithelial morphogenesis and axon branching; kal-1 transcriptional reporters reveal expression beginning in the 50-cell stage embryo in 2-3 cells with later embryonic expression in at least 8-10 AB-derived ventral neuroblasts that are a substrate for migrating epidermal cells during ventral enclosure; later expression in larvae and adults is restricted to anterior neurons, including AIY, AIZ, RID, M5, ASI, and labial sensory neurons, ventral nerve cord motorneurons, midbody neurons HSN, CAN, and PVM, tail neurons DVB, DVC, and PDB, and the nonneuronal excretory cell as well as in uterine muscles; in the AIY interneurons, kal-1 is part of a gene battery whose expression is under the control of the CEH-10 and TTX-3 Paired and LIM-type homeodomains, respectively. WormBase CDS description: WAP-type (Whey Acidic Protein) 'four-disulfide core', Fibronectin type III domain (3 domains)
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, ViswanathanM et al 2005  S2                                  
                                              daf-16 Resveratrol                                                                 

K04B12.1 Aff_K04B12.1 P W All gene names: plx-2; K04B12.1; 2O704; CE35575; NM_064600; WBGene00004048; WP:CE35575
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster A, Reinke et al 2004, list of genes in cluster                             
                                              order, ViswanathanM et al 2005  S2 sir-2.1 regulated                               

K04G7.1 Aff_K04G7.1 P W All gene names: K04G7.1; 3I253; CE01358; WBGene00019400; WP:CE01358
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster F, Reinke et al 2004, fem1 enriched genes,                                 
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt vs glp-4 enriched genes, Reinke et al 2004,                            
                                              wt herm vs wt male enriched gen, ViswanathanM et al                                
                                              2005  S2 daf-16 Resveratrol, ViswanathanM et al 2005                               
                                              S2 sir-2.1 regulated                                                               

K07B1.1 Aff_K07B1.1 P W All gene names: try-5; K07B1.1; 5J829; CE35334; NM_073020; WBGene00006623; WP:CE35334
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, wt herm vs wt herm                             
                                              enriched gen, Reinke et al 2004, GO categories, Reinke                             
                                              et al 2004, IVb male soma enriched genes                                           

K08E3.7 Aff_K08E3.7 P W All gene names: pdr-1; K08E3.7; K08E3.7.1; K08E3.7.2; 3O861; CE31713; NM_067445; WBGene00003967; WP:CE31713 WormBase description: pdr-1 encodes an ortholog of human parkin (PARK2; OMIM:602544), which when mutated leads to the juvenile 2 form of Parkinson disease (OMIM:600116).
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, ViswanathanM et al 2005  S2                                  
                                              sir-2.1 regulated                                                                  

K08F9.4 Aff_K08F9.4 P W All gene names: K08F9.4; 5P625; CE11948; WBGene00010687; WP:CE11948
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, list of genes in cluster                                 
                                              order, Reinke et al 2004, oogenesis enriched genes,                                
                                              Reinke et al 2004, wt vs glp-4 enriched genes, Reinke                              
                                              et al 2004, wt herm vs wt male enriched gen, Reinke et                             
                                              al 2004, list of genes in cluster E, ViswanathanM et al                            
                                              2005  S2 daf-16 Resveratrol, ViswanathanM et al 2005                               
                                              S2 sir-2.1 regulated                                                               

K09D9.1 Aff_K09D9.K P W All gene names: K09D9.1; K09D9.K; 5E499; CE21055; WBGene00019564; WP:CE21055
                                              
Member of lists (Publications lists):
                                              Lund et al 2002  Fig1 aging-regulated                             
                                              genes, Reinke et al 2004, IVb male soma enriched genes                             

K10B3.10 Aff_K10B3.10 P W All gene names: imo-1; spc-1; K10B3.10; CE07373; NM_076136; WBGene00004951; WP:CE07373; XD738 WormBase description: spectrin alpha chain
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster order, Reinke et al 2004, list of genes in                              
                                              cluster C                                                                          

K10C3.4 Aff_K10C3.4 P W All gene names: K10C3.4; 1K441; CE12080; WBGene00010731; WP:CE12080
                                              
Member of lists (Publications lists):
                                              Lund et al 2002  Fig1 aging-regulated                             
                                              genes, Reinke et al 2004, fem1 enriched genes, Reinke                              
                                              et al 2004, list of genes in cluster order, Reinke et                              
                                              al 2004, mixed oogenesis soma, Reinke et al 2004, list                             
                                              of genes in cluster E, ViswanathanM et al 2005  S2                                 
                                              sir-2.1 regulated, ViswanathanM et al 2005  S2 daf-16                              
                                              Resveratrol                                                                        

K10C9.3 Aff_K10C9.3 P W All gene names: K10C9.3; 5B565; CE28601; WBGene00019624; WP:CE28601 WormBase description: ribonuclease
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster order, Reinke et al 2004, list of genes in                              
                                              cluster C, Romagnolo et al 2002  Fig3b Metabolism                                  

K11D2.3 Aff_K11D2.3 P W All gene names: unc-101; K11D2.3; K11D2.3.1; K11D2.3.2; 1N105; CE28050; NM_060773; WBGene00006829; WP:CE28050 WormBase description: unc-101 encodes an adaptin orthologous to the mu1-I subunit of adaptor protein complex 1 (AP-1) that is involved in motility, egg-laying, negative regulation of LET-23 / EGF-receptor signalling, and localization of the neuronal receptors ODR-10 and GLR-1; it is broadly expressed.
K12H4.1 Aff_K12H4.1 P W All gene names: ceh-26; K12H4.1; 3J159; CE00266; NM_066359; WBGene00000448; WP:CE00266 WormBase description: ceh-26 encodes a protein that contains a prospero-related homeodomain; expressed in nuclei of the adult head, tail neurons, and one cell in the postdeirids.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Wang et al 2003  S4 Early genes,                             
                                              Wang et al 2003  S3  genes pass one-way ANOVA, Wang et                             
                                              al 2003  S4 genes pass two-wayANOVA P0                                             

M01A8.1 Aff_M01A8.1 P W All gene names: M01A8.1; 3K349; CE00275; WBGene00010795; WP:CE00275
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Dauer specific genes                            
                                              P<0.05, ViswanathanM et al 2005  S2 daf-16 Resveratrol,                            
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated, Wang et                             
                                              al 2003  S4 TransientList, Wang et al 2003  S3  genes                              
                                              pass one-way ANOVA, Wang et al 2003  S8 SAGE genes in                              
                                              the dauer exit, Wang et al 2003  S7 SAGE genes in the                              
                                              dataset, Wang et al 2003  S4 genes pass two-wayANOVA P0                            

M01D7.2 Aff_M01D7.2 P W All gene names: scm-1; M01D7.2; 1C336; CE25946; NM_058510; SCAMP; WBGene00004743; WP:CE25946
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph                                                               

M04B2.1 Aff_M04B2.1 P W All gene names: gei-2; mep-1; M04B2.1; 4M291; CE31852; NM_069772; WBGene00003218; WP:CE31852 WormBase description: mep-1 is required for repression by the fem-3 3' UTR in vivo, and for maintenance of somatic (versus germline) differentiation; MEP-1 protein has zinc-finger domains and a glutamine/asparagine-rich domain. WormBase CDS description: zinc-finger protein
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster F, Reinke et al 2004, fem1 enriched genes,                              
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, mixed oogenesis soma                                            

M04G12.4 Aff_M04G12.4 P W All gene names: M04G12.4; M04G12.4b.1; M04G12.4b.2; M04G12.4b.3; 5N866; CE36495; CE36496; WBGene00010868; WP:CE36495; WP:CE36496 WormBase description: Zinc finger, C2H2 type
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster A, Reinke et al 2004, list of genes in cluster                             
                                              order, ViswanathanM et al 2005  S2 sir-2.1 regulated,                              
                                              Wang et al 2003  S4 Early genes, Wang et al 2003  S3                               
                                              genes pass one-way ANOVA, Wang et al 2003  S4 genes                                
                                              pass two-wayANOVA P0                                                               

R02C2.1 Aff_R02C2.1 P W All gene names: R02C2.1; 5A716; CE33150; WBGene00019814; WP:CE33150 WormBase description: protein kinase
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 daf-16                                
                                              Resveratrol                                                                        

R05D11.9 Aff_R05D11.5 P W All gene names: R05D11.9; 1J171; CE32474; WBGene00011037; WP:CE32474
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, wt herm vs wt male enriched gen, ViswanathanM et                             
                                              al 2005  S2 sir-2.1 regulated                                                      

R05D3.7 Aff_R05D3.7 P W All gene names: khc-1; unc-116; R05D3.7; 3J442; CE26945; NM_066441; WBGene00006840; WP:CE26945 WormBase description: Kinesin heavy chain
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, ViswanathanM et al 2005  S2                                  
                                              sir-2.1 regulated                                                                  

R10D12.11 Aff_R10D12.11 P W All gene names: srh-24; R10D12.11; 5O438; CE38095; NM_074065; WBGene00011192; WP:CE38095
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

R10E11.1 Aff_R10E11.1 P W All gene names: cbp-1; cep-1; R10E11.1; 3K863; CE21117; CE28069; NM_066759; NM_066760; WBGene00000366; WP:CE21117; WP:CE28069 WormBase description: cbp-1 encodes a homolog of the mammalian transcriptional cofactors CBP (OMIM:600140) and p300 (E1A-BINDING PROTEIN, 300-KD; OMIM:602700) that have been shown to possess histone acetyltransferase activity, and which, when mutated, lead to Rubinstein-Taybi syndrome (OMIM:180849) and colorectal cancer (OMIM:114500); at least one splicing form of CBP-1 exhibits histone acetyltransferase (HAT) activity in vitro and has a glutamine/asparagine-rich domain; CBP-1 is required during embryogenesis for differentiation of all non-neuronal somatic cell types; CBP-1 is expressed very early in embryogenesis, suggesting that it may interact with maternally provided transcription factors, such as SKN-1, to specific developmental fates.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph                                                               

R10E11.6 Aff_R10E11.6 P W All gene names: R10E11.6; CE39757; CE39758; NM_066766; WBGene00011218; WP:CE39757; WP:CE39758
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated, ViswanathanM et al 2005  S2 daf-16                                      
                                              Resveratrol                                                                        

R10E12.2 Aff_R10E12.2 P W All gene names: R10E12.2; 3L50; CE00311; WBGene00011221; WP:CE00311
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 daf-16                                
                                              Resveratrol                                                                        

R11A5.3 Aff_R11A5.3 P W All gene names: R11A5.3; 1I438; CE12726; WBGene00011231; WP:CE12726
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order, Reinke et al 2004, list of genes in                                 
                                              cluster E, ViswanathanM et al 2005  S2 sir-2.1                                     
                                              regulated                                                                          

R13.4 Aff_R13.1 P W All gene names: R13.4; CE39269; WBGene00011259; WP:CE39269
R13A5.5 Aff_R13A5.5 P W All gene names: ceh-13; R13A5.5; 3I647; CE28767; NM_066254; WBGene00000437; WP:CE28767 WormBase description: a homolog of Hox genes of labial/Hox1 type; affects viability, body shape and anterior patterning during embryogenesis, interacts genetically with hox genes; and is expressed in A, D, E and MS lineages in the early embryo, and in the anterior dorsal hypodermal cells, anterior body wall muscle cells, and in the cells of the prospective ventral nerve cord at the comma stage; and in the ventral nerve cord and and ventral and dorsal hypodermal cells in L1 larvae.
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Dauer specific genes                            
                                              P<0.05, McCarroll et al 2004  SFig1-4 conserved w/                                 
                                              Drosoph, Wang et al 2003  S6 removed genes of                                      
                                              contamination, Wang et al 2003  S7 SAGE genes in the                               
                                              dataset, Wang et al 2003  S8 SAGE genes in the dauer                               
                                              exit                                                                               

R90.1 Aff_R90.1 P W All gene names: R90.1; 5N372; CE06325; WBGene00011283; WP:CE06325 WormBase description: casein Kinase I
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster A, Reinke et al 2004, list of genes in                                  
                                              cluster order, ViswanathanM et al 2005  S2 sir-2.1                                 
                                              regulated                                                                          

T02C1.1 Aff_T02C1.1 P W All gene names: T02C1.1; 3K337; CE00312; WBGene00011365; WP:CE00312 WormBase description: Zinc finger, C3HC4 type (RING finger)
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 daf-16                                
                                              Resveratrol                                                                        

T02E1.2 Aff_T02E1.2 P W All gene names: T02E1.2; 1I796; CE32480; WBGene00011375; WP:CE32480
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, list of genes in cluster F, Reinke et al                               
                                              2004, wt vs glp-4 enriched genes, Reinke et al 2004,                               
                                              list of genes in cluster order, Reinke et al 2004, wt                              
                                              herm vs wt male enriched gen, ViswanathanM et al 2005                              
                                              S2 sir-2.1 regulated, ViswanathanM et al 2005  S2                                  
                                              daf-16 Resveratrol                                                                 

T04A8.3 Aff_T04A8.3 P W All gene names: T04A8.3; 3F770; CE39624; WBGene00011405; WP:CE39624 WormBase description: C-type lectin
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order, Reinke et al 2004, spermatogenesis                                  
                                              enriched genes, Reinke et al 2004, wt herm vs wt herm                              
                                              enriched gen, Reinke et al 2004, fem3 enriched genes,                              
                                              Reinke et al 2004, wt vs glp-4 enriched genes, Reinke                              
                                              et al 2004, wt males vs glp4 male enriched , Reinke et                             
                                              al 2004, list of genes in cluster D, Reinke et al 2004,                            
                                              shared sperm, ViswanathanM et al 2005  S2 sir-2.1                                  
                                              regulated                                                                          

T04D1.4 Aff_T04D1.4 P W All gene names: tag-192; T04D1.4; 1F262; CE18196; WBGene00007053; WBGene00020213; WP:CE18196 WormBase description: helicase
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph                                                               

T05E7.5 Aff_T05E7.5 P W All gene names: T05E7.5; 1G778; CE13239; NM_059386; WBGene00020261; WP:CE13239
                                              
Member of lists (Publications lists):
                                              Romagnolo et al 2002  Fig3b Cell                                  
                                              Structure, ViswanathanM et al 2005  S2 sir-2.1                                     
                                              regulated                                                                          

T05G5.8 Aff_T05G5.8 P W All gene names: T05G5.8; 3K844; CE21152; WBGene00011502; WP:CE21152
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, list of genes in cluster F,                            
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated, Wang et                             
                                              al 2003  S5 genes common to feeding ANOVA, Wang et al                              
                                              2003  S3  genes pass one-way ANOVA                                                 

T06E4.9 Aff_T06E4.9 P W All gene names: T06E4.9; 5K101; CE23952; WBGene00011536; WP:CE23952
                                              
Member of lists (Publications lists):
                                              Bishop et al 2004  T4 57 vhl-1 depend                             
                                              hif-1 indep, Reinke et al 2004, list of genes in                                   
                                              cluster order, Reinke et al 2004, list of genes in                                 
                                              cluster C, ViswanathanM et al 2005  S2 daf-16                                      
                                              Resveratrol                                                                        

T07A5.2 Aff_T07A5.2 P W All gene names: T07A5.2; 3L404; CE36501; WBGene00011555; WP:CE36501 WormBase description: YK10 homolog
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph                                                                            

T07C4.8 Aff_T07C4.8 P W All gene names: ced-9; T07C4.8; 3L427; CE25104; NM_066883; WBGene00000423; WP:CE25104 WormBase description: ced-9 is required for control of programmed cell death during development; it encodes the only C. elegans homolog of BCL-2. WormBase CDS description: Apoptosis regulator proteins, Bcl-2 family
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order, Reinke et al 2004, list of genes in                                 
                                              cluster E, ViswanathanM et al 2005  S2 sir-2.1                                     
                                              regulated                                                                          

T07D3.7 Aff_T07D3.7 P W All gene names: alg-2; T07D3.7; TO7D3.7; 2B167; CE13367; CE32063; NM_061436; NM_182192; WBGene00000106; WP:CE13367; WP:CE32063 WormBase description: alg-2 encodes a PAZ and PIWI-domain containing protein that is a member of the highly conserved eukaryotic RDE-1/AGO1/PIWI family of proteins that regulate posttranscriptional gene silencing (PTGS); ALG-2 functions with ALG-1 to control specific developmental timing events by positively regulating expression of small temporal RNAs (stRNAs) encoded by lin-4 and let-7; ALG-2 and ALG-1 are also required for RNAi in the germline, although they are not required for RNAi in the soma.
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

T07F10.3 Aff_T07F10.3 P W All gene names: T07F10.3; 5N348; CE06396; WBGene00011589; WP:CE06396 WormBase description: polyadenylate-binding protein like
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster order, Reinke et al 2004, intrinsic, Reinke                             
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, wt herm vs wt male enriched gen, Reinke et al                                
                                              2004, GO categories, Reinke et al 2004, list of genes                              
                                              in cluster E, ViswanathanM et al 2005  S2 sir-2.1                                  
                                              regulated                                                                          

T09E8.1 Aff_T09E8.1 P W All gene names: T09E8.1; CE31987; CE31988; CE31989; CE31990; CE31991; CE39958; WBGene00011647; WP:CE31987; WP:CE31988; WP:CE31989; WP:CE31990; WP:CE31991; WP:CE39958
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

T10E9.8 Aff_T10E9.8 P W All gene names: T10E9.8; 1H114; CE13557; WBGene00020418; WP:CE13557
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 daf-16                                
                                              Resveratrol                                                                        

T10H4.6 Aff_T10H4.6 P W All gene names: srw-17; T10H4.6; 5P754; CE16391; NM_074382; WBGene00005764; WP:CE16391 WormBase description: 7TM chemoreceptor, srw family
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 daf-16                                
                                              Resveratrol, Wang et al 2003  S3  genes pass one-way                               
                                              ANOVA, Wang et al 2003  S4 Dauer Enriched, Wang et al                              
                                              2003  S4 genes pass two-wayANOVA P0                                                

T13H2.5 Aff_T13H2.3 P W All gene names: T13H2.5; CE31236; CE38222; WBGene00020496; WP:CE31236; WP:CE38222; XF222
T14G10.2 Aff_T14G10.2 P W All gene names: pxf-1; ra-gef; T14G10.2; T14G10.2a.1; T14G10.2a.2; T14G10.2b.1; T14G10.2b.2; 4K930; CE28080; CE28081; PXF; WBGene00004254; WP:CE28080; WP:CE28081 WormBase description: cell division control protein 25 like
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, mixed oogenesis soma,                                    
                                              ViswanathanM et al 2005  S2 daf-16 Resveratrol                                     

T16H12.5 Aff_T16H12.5 P W All gene names: bath-43; T16H12.5; T16H12.5b.1; T16H12.5b.2; T16H12.5b.3; 3L182; CE00510; CE29054; WBGene00011815; WP:CE00510; WP:CE29054 WormBase description: The T16H12.5 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis. WormBase CDS description: Kruppel-like zinc finger protein (outside zinc fingers)
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster A, Reinke et al 2004, list of genes in                                  
                                              cluster order, Shen et al 2005  T1 hif-1indepen                                    
                                              hypoxia, ViswanathanM et al 2005  S2 sir-2.1 regulated                             

T17A3.2 Aff_T17A3.2 P W All gene names: T17A3.2; 3A753; CE37151; WBGene00020540; WP:CE37151
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 daf-16                                
                                              Resveratrol                                                                        

T17A3.7 Aff_T17A3.7 P W All gene names: fbxb-84; T17A3.7; 3A764; CE19584; NM_064756; WBGene00020544; WP:CE19584 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
                                              
Member of lists (Publications lists):
                                              Murphy et al 2003  Fig2 Class2 shorten                            
                                              lifespan, Reinke et al 2004, list of genes in cluster                              
                                              order, Reinke et al 2004, list of genes in cluster E,                              
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

T18H9.6 Aff_T18H9.6 P W All gene names: mdt-27; T18H9.6; 5J690; CE04974; NM_072985; WBGene00007023; WP:CE04974
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, list of genes in cluster                                 
                                              order, Reinke et al 2004, wt herm vs wt male enriched                              
                                              gen, Reinke et al 2004, mixed oogenesis soma, Reinke et                            
                                              al 2004, list of genes in cluster E, ViswanathanM et al                            
                                              2005  S2 sir-2.1 regulated                                                         

T19B4.7 Aff_T19B4.6 P W All gene names: unc-40; unc-91; T19B4.7; 1G248; CE25115; NM_059263; WBGene00006776; WP:CE25115 WormBase description: The unc-40 gene encodes a netrin receptor that is required to guide dorsal-ventral cell and axon migrations, and is required for correct polarization and migration of the neuroblasts QL and QR. WormBase CDS description: membrane protein
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt herm vs wt male enriched gen, Reinke et al                             
                                              2004, list of genes in cluster E                                                   

T20B5.1 Aff_T20B5.1 P W All gene names: apa-2; apt-4; T20B5.1; T20B5.1.1; T20B5.1.2; CE28680; NM_077171; WBGene00000161; WP:CE28680; XJ961 WormBase description: The apt-4 gene encodes an adaptin: specifically, it encodes an ortholog of the alpha subunit of adaptor protein complex 2 (AP-2). WormBase CDS description: alpha-adaptin
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, list of genes in cluster                               
                                              order, Reinke et al 2004, list of genes in cluster B,                              
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

T20D4.19 Aff_T20D4.19 P W All gene names: T20D4.19; 5D900; CE13814; WBGene00020624; WP:CE13814
T21E3.3 Aff_T21E3.3 P W All gene names: lrp-2; T21E3.3; 1E504; CE28688; NM_058869; WBGene00003072; WP:CE28688 WormBase description: EGF-like protein
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 daf-16                                
                                              Resveratrol                                                                        

T21H8.1 Aff_T21H8.1 P W All gene names: CELIPRIN-BETA; T21H8.1; CE37412; WBGene00011904; WP:CE37412; XO484
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster order, Reinke et al 2004, list of genes in                              
                                              cluster B                                                                          

T22A3.8 Aff_C43H8.3, Aff_T22A3.8 P W All gene names: lam-3; T22A3.8; 1L197; CE31067; NM_060374; WBGene00002248; WP:CE31067; lama1/2 WormBase description: lam-3 is orthologous to human LAMININ ALPHA-2 (LAMA2; OMIM:156225), which when mutated leads to merosin-deficient congenital muscular dystrophy. WormBase CDS description: laminin B
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph                                                               

T23D8.9 Aff_T23D8.9 P W All gene names: sys-1; T23D8.9; 1K556; CE18959; CE27209; WBGene00006379; WBGene00011946; WP:CE18959; WP:CE27209 WormBase description: sys-1 encodes a novel protein that contains three divergent armadillo repeats; during gonadogenesis, SYS-1 functions in a Wnt/MAPK signaling pathway as a dosage-dependent beta-catenin-like transcriptional coactivator required for specification of distal cell fates; consistent with its role as a beta-catenin, SYS-1 interacts, in yeast two-hybrid and coimmunoprecipitation assays, with the POP-1/TCF transcription factor with which it can stimulate transcription via TCF binding sites; in two hybrid-assays, the POP-1/SYS-1 interaction requires the N-terminal beta-catenin binding domain of POP-1, and most of the SYS-1 protein; the SYS-1 expression pattern is not yet known.
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, oogenesis enriched genes,                                       
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated,                                     
                                              ViswanathanM et al 2005  S2 daf-16 Resveratrol                                     

T23G5.3 Aff_T23G5.3 P W All gene names: T23G5.3; 3K318; CE37793; WBGene00011963; WP:CE37793
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

T24B8.3 Aff_T24B8.3 P W All gene names: T24B8.3; T24B8.3a.1; T24B8.3a.2; T24B8.3b.1; T24B8.3b.2; 2J350; CE35910; CE35911; WBGene00011977; WP:CE35910; WP:CE35911
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster A, Reinke et al 2004, list of genes in cluster                             
                                              order                                                                              

T26A5.5 Aff_T26A5.5 P W All gene names: T26A5.5; T26A5.5b.1; T26A5.5b.2; 3H549; CE32733; CE32734; WBGene00020821; WP:CE32733; WP:CE32734
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt herm vs wt male enriched gen, ViswanathanM                             
                                              et al 2005  S2 sir-2.1 regulated                                                   

T26C11.7 Aff_T26C11.7 P W All gene names: ceh-39; T26C11.7; CE05026; NM_075941; WBGene00000460; WP:CE05026; XC474 WormBase description: ceh-39 encodes a a ONECUT class CUT homeobox protein with a single N-terminal cut domain; CEH-39 acts as an X-signal element (XSE) to affect sex determination; the cut domain may be a compact DNA-binding domain composed of alpha helices; ceh-39 is one of three nematode-specific ONECUT genes in a cluster with ceh-21 and ceh-41. WormBase CDS description: homeobox
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt herm vs wt male enriched gen, Reinke et al                             
                                              2004, list of genes in cluster E                                                   

T26H2.3 Aff_T26H2.3 P W All gene names: fbxb-2; T26H2.3; 5T706; CE16489; WBGene00012065; WP:CE16489 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated, ViswanathanM et al 2005  S2 daf-16                                      
                                              Resveratrol                                                                        

T28A11.15 Aff_T28A11.15 P W All gene names: srt-63; T28A11.15; 5D732; CE35788; NM_071493; WBGene00020877; WP:CE35788 WormBase description: 7TM chemoreceptor, srt family
T28F4.1 Aff_T28F4.1 P W All gene names: T28F4.1; T28F4.1.1; T28F4.1.2; T28F4.1.3; 1I50; CE06523; WBGene00012136; WP:CE06523
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated, Wang et al 2003  S4 Early genes, Wang et al                             
                                              2003  S3  genes pass one-way ANOVA, Wang et al 2003  S4                            
                                              genes pass two-wayANOVA P0                                                         

VW02B12L.3 Aff_VW02B12L.3 P W All gene names: ebp-2; VW02B12L.3; VW02B12L.3.1; VW02B12L.3.2; 2L733; CE18982; WBGene00012156; WP:CE18982
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, list of genes in cluster F, Reinke et al                               
                                              2004, wt vs glp-4 enriched genes, Reinke et al 2004,                               
                                              list of genes in cluster order                                                     

W02A11.3 Aff_W02A11.3 P W All gene names: W02A11.3; W02A11.3.1; W02A11.3.2; 1N331; CE18990; WBGene00012194; WP:CE18990 WormBase description: Zinc finger, C3HC4 type (RING finger)
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

W02C12.1 Aff_W02C12.1 P W All gene names: W02C12.1; 4E777; CE14412; WBGene00020928; WP:CE14412 WormBase description: EGF-like protein
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster A, Reinke et al 2004, list of genes in cluster                             
                                              order, ViswanathanM et al 2005  S2 sir-2.1 regulated,                              
                                              ViswanathanM et al 2005  S2 daf-16 Resveratrol                                     

W02D3.10 Aff_W02D3.10 P W All gene names: W02D3.10; 1H326; CE34383; CE34384; WBGene00020935; WP:CE34383; WP:CE34384
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, wt herm vs wt male enriched gen, ViswanathanM et                             
                                              al 2005  S2 sir-2.1 regulated, ViswanathanM et al 2005                             
                                              S2 daf-16 Resveratrol                                                              

W02F12.6 Aff_W02F12.6 P W All gene names: W02F12.6; 5H190; CE31084; WBGene00020951; WP:CE31084
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt herm vs wt male enriched gen, Reinke et al                             
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated                                                         

W03F9.5 Aff_W01A6.J P W All gene names: ttb-1; W03F9.5; W03F9.5.1; W03F9.5.2; W03F9.5.3; 5A645; CE27396; CETFIIB; NM_070745; WBGene00006648; WP:CE27396 WormBase description: transcription factor
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, list of genes in cluster F,                            
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs                             
                                              glp-4 enriched genes, ViswanathanM et al 2005  S2                                  
                                              daf-16 Resveratrol, ViswanathanM et al 2005  S2 sir-2.1                            
                                              regulated                                                                          

W05H12.2 Aff_W05H12.2 P W All gene names: W05H12.2; 1O0; CE14660; WBGene00012290; WP:CE14660
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

W06H8.8 Aff_W06H8.C P W All gene names: tag-211; tag-58; tag-7; ttn-1; W06H8.8; Y38B5A.A; 5G672; CE31088; CE36722; CE36723; CE36724; CE36725; CE36726; CE36727; WBGene00006436; WBGene00021069; WP:CE31088; WP:CE36722; WP:CE36723; WP:CE36724; WP:CE36725; WP:CE36726; WP:CE36727
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes                                             

Y105C5A.1 Aff_Y105C5.A P W All gene names: Y105C5A.1; 4Q316; CE23184; WBGene00013632; WP:CE23184
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order                                                                      

Y106G6H.4 Aff_Y106G6H.4 P W All gene names: Y106G6H.4; 1L14; CE20414; WBGene00013717; WP:CE20414
Y23H5A.5 Aff_Y23H5A.6 P W All gene names: ctn-1; Y23H5A.5; Y23H5A.5d.1; Y23H5A.5d.2; 1D185; CE24191; CE30315; CE30316; CE31096; NM_058607; NM_058608; NM_170829; NM_170830; WBGene00000832; WP:CE24191; WP:CE30315; WP:CE30316; WP:CE31096 WormBase description: ctn-1 encodes a protein that belongs to the alpha-catulin family of catenin-like proteins; the precise function of ctn-1 is not yet known; the CTN-1 promoter-GFP fusion protein is expressed in body wall, vulval and anal muscle tissues.
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

Y26D4A.5 Aff_Y26D4A.E P W All gene names: Y26D4A.5; 1N669; CE39648; WBGene00012503; WP:CE39648
Y37E11AR.6 Aff_Y37E11A_93.A P W All gene names: efn-1; vab-2; Y37E11AR.6; 4E526; CE27606; NM_068011; WBGene00006869; WP:CE27606 WormBase description: The vab-2 gene encodes an ephrin molecule related to human ephrin B2 (OMIM:600527); VAB-2, expressed primarily in neuronal cells, is a ligand for the VAB-1 ephrin receptor and plays a role in embryonic cell movements, epidermal morphogenesis during later embryogenesis, and oocyte maturation; VAB-2 synergizes with PTP-3, a LAR-like receptor tyrosine phosphatase, to regulate morphogenesis.
                                              
Member of lists (Publications lists):
                                              Bishop et al 2004  T4 57 vhl-1 depend                             
                                              hif-1 indep, Reinke et al 2004, fem1 enriched genes,                               
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, mixed oogenesis soma, Reinke et al                              
                                              2004, list of genes in cluster B                                                   

Y38F2AL.1 Aff_Y38F2A_5743.J P W All gene names: Y38F2AL.1; 4D91; CE39822; WBGene00021415; WP:CE39822 WormBase description: Y38F2AL.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; Y38F2AL.1 is worm-specific, with obvious homologs only in C. elegans; Y38F2AL.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order, Reinke et al 2004, list of genes in                                 
                                              cluster B, ViswanathanM et al 2005  S2 sir-2.1                                     
                                              regulated, Wang et al 2003  S5 genes common to feeding                             
                                              ANOVA, Wang et al 2003  S3  genes pass one-way ANOVA                               

Y39B6A.12 Aff_Y39B6.T P W All gene names: Y39B6A.12; Y39B6B.T; Y39B6B.U; 5T594; CE29855; CE38444; WBGene00012674; WP:CE29855; WP:CE38444
Y41D4B.6 Aff_Y41D4B_930.B P W All gene names: Y41D4B.6; 4C401; CE39048; WBGene00021513; WP:CE39048
Y44E3A.6 Aff_Y44E3A.C P W All gene names: Y44E3A.6; Y44E3A.A; 1D910; CE31372; CE31373; WBGene00021551; WP:CE31372; WP:CE31373
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  T3 20 most abundant                             
                                              Mixed-stage, Reinke et al 2004, fem1 enriched genes,                               
                                              Reinke et al 2004, mixed oogenesis soma, ViswanathanM                              
                                              et al 2005  S2 daf-16 Resveratrol                                                  

Y46H3A.6 Aff_Y46H3A.A P W All gene names: gly-7; Y46H3A.6; Y46H3A.A; 5C296; CE24309; NM_071111; WBGene00001632; WP:CE24309 WormBase description: gly-7 encodes an N-acetylgalactosaminyltransferase that exhibits activity when expressed in COS7 cells. WormBase CDS description: N-acetylgalactosaminyltransferase
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Wang et al 2003  S5 genes common                             
                                              to feeding ANOVA, Wang et al 2003  S3  genes pass                                  
                                              one-way ANOVA                                                                      

Y49E10.6 Aff_Y49E10.A P W All gene names: his-72; Y49E10.6; Y49E10.6.1; Y49E10.6.2; Y49E10.A; 3N456; CE22223; NM_067207; WBGene00001946; WP:CE22223 WormBase description: his-72 encodes an H3 histone required for embryonic viability. WormBase CDS description: Core histone H2A/H2B/H3/H4
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, GO categories, ViswanathanM et al 2005  S2                                
                                              sir-2.1 regulated                                                                  

Y4C6B.1 Aff_Y4C6B.H P W All gene names: Y4C6B.1; Y4C6B.H; 4G119; CE21305; WBGene00021155; WP:CE21305
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, wt herm vs wt male enriched gen, Reinke et al                                
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated                                                         

Y52D3.1 Aff_Y52D3.1 P W All gene names: Y52D3.1; Y52D3.1a.1; Y52D3.1a.2; Y52D3.1a.3; 3M39; CE19223; WBGene00013132; WP:CE19223 WormBase description: serine/threonine kinase
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

Y54E5A.6 Aff_Y105E8A.FF P W All gene names: Y54E5A.6; 1P300; CE20317; WBGene00013201; WP:CE20317 WormBase description: This gene encodes a protein predicted by Eisenberg and coworkers, with 52% accuracy, to be mitochondrial. WormBase CDS description: Uncharacterized protein family UPF0034, Double-stranded RNA binding motif
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph                                                                            

Y55D5A.1 Aff_Y55D5A_392.F P W All gene names: Y55D5A.1; 3E77; CE27294; CE34131; WBGene00021915; WP:CE27294; WP:CE34131
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated, ViswanathanM et al 2005  S2 daf-16                                      
                                              Resveratrol                                                                        

Y56A3A.15 Aff_Y56A3A.M P W All gene names: fbxb-24; Y56A3A.15; Y56A3A.G; 3M999; CE22582; WBGene00013234; WP:CE22582 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
                                              
Member of lists (Publications lists):
                                              Murphy et al 2003  Fig2 Class2 shorten                            
                                              lifespan, Reinke et al 2004, list of genes in cluster                              
                                              order, Reinke et al 2004, list of genes in cluster E,                              
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

Y56A3A.29 Aff_Y56A3A.CC P W All gene names: ung-1; Y56A3A.29; 3N62; CE22594; CE28139; WBGene00013241; WP:CE22594; WP:CE28139
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, Reinke et al 2004, fem1 enriched genes,                                  
                                              Reinke et al 2004, wt vs glp-4 enriched genes, Reinke                              
                                              et al 2004, oogenesis enriched genes, Reinke et al                                 
                                              2004, wt herm vs wt male enriched gen                                              

Y67D8A.1 Aff_Y67D8A_373.A P W All gene names: Y67D8A.1; Y67D8A.1.1; Y67D8A.1.2; 4E15; CE31660; WBGene00022058; WP:CE31660 WormBase description: Y67D8A.1 is orthologous to the human gene PHOSPHORYLASE KINASE, BETA SUBUNIT (PHKB; OMIM:172490), which when mutated leads to glycogen storage disease.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, ViswanathanM et al 2005  S2                                  
                                              sir-2.1 regulated, ViswanathanM et al 2005  S2 daf-16                              
                                              Resveratrol                                                                        

Y71F9AL.1 Aff_Y71F9A_270.A P W All gene names: Y71F9AL.1; 1D495; CE29909; WBGene00022107; WP:CE29909
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke                            
                                              et al 2004, mixed oogenesis soma                                                   

Y71F9B.8 Aff_Y71F9B_297.C P W All gene names: Y71F9B.8; 1D304; CE25571; WBGene00022129; WP:CE25571
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph                                                               

Y71G12B.20 Aff_Y71G12A_205.G P W All gene names: mab-20; Y71G12B.20; 1C118; CE22926; CE33246; NM_058474; WBGene00003111; WP:CE22926; WP:CE33246
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph                                                               

Y87G2A.18 Aff_Y87G2A.D P W All gene names: Y87G2A.18; 1O104; CE23124; WBGene00013604; WP:CE23124
ZC262.3 Aff_ZC262.3 P W All gene names: ZC262.3; 3J416; CE27345; CE29616; WBGene00022580; WP:CE27345; WP:CE29616 WormBase description: N-CAM IG domain
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, wt herm vs wt male                             
                                              enriched gen, ViswanathanM et al 2005  S2 sir-2.1                                  
                                              regulated                                                                          

ZC395.6 Aff_ZC395.6 P W All gene names: gro-1; ZC395.6; 3G355; CE30119; NM_065721; WBGene00001740; WP:CE30119 WormBase description: This gene encodes a protein predicted by Eisenberg and coworkers, with 52% accuracy, to be mitochondrial. WormBase CDS description: tRNA isopentenyltransferase
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Non dauer genes                                 
                                              P<0.05, Jones et al 2001  T2 lifespan and Dauer,                                   
                                              McCarroll et al 2004  SFig5 conserved w/ yeast, Reinke                             
                                              et al 2004, list of genes in cluster order, Reinke et                              
                                              al 2004, intrinsic, Reinke et al 2004, wt vs glp-4                                 
                                              enriched genes, Reinke et al 2004, wt herm vs wt male                              
                                              enriched gen, Reinke et al 2004, list of genes in                                  
                                              cluster E, ViswanathanM et al 2005  S2 sir-2.1                                     
                                              regulated                                                                          

ZK1058.2 Aff_ZK1058.2 P W All gene names: epi-2; pat-3; ZK1058.2; ZK1058.2.1; ZK1058.2.2; 3F0; CE01102; INTB/1; NM_065386; WBGene00003930; WP:CE01102 WormBase description: beta integrin
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, mixed oogenesis soma,                                    
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

ZK112.7 Aff_ZK112.7 P W All gene names: cdh-3; ZK112.7; 3I832; CE00378; NM_066286; WBGene00000395; WP:CE00378 WormBase description: cdh-3 encodes a member of the cadherin superfamily that affects morphogenesis of tail epithelia and excretory function; expressed predominantly in developing epithelial cells, and also expressed in the AC, excretory cell, various neurons, and vulval cells during different stages of development. WormBase CDS description: fat tumor suppressor
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

ZK1236.3 Aff_ZK1236.3 P W All gene names: phi-57; ZK1236.3; 3J511; CE00532; WBGene00023405; WP:CE00532
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, mixed oogenesis soma,                                    
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

ZK328.4 Aff_ZK328.4 P W All gene names: ZK328.4; 3H96; CE28182; WBGene00022694; WP:CE28182
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, intrinsic,                                
                                              Reinke et al 2004, list of genes in cluster F, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, wt herm vs wt male enriched gen                                              

ZK377.2 Aff_ZK377.2 P W All gene names: sax-3; ZK377.2; CE25688; CE31267; NM_171652; WBGene00004729; WP:CE25688; WP:CE31267; XE72 WormBase description: The protein product of sax-3 is homologous to Drosophila ROUNDABOUT; in larval hermaphrodites, SAX-3 is required to confine migrating sex myoblasts to the ventral muscle quadrants during their migration through the body.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, mixed oogenesis soma                                     

ZK381.5 Aff_ZK381.5 P W All gene names: ZK381.5; 4H744; CE31750; CE31751; WBGene00022727; WP:CE31750; WP:CE31751
                                              
Member of lists (Publications lists):
                                              Wang et al 2003  S3  genes pass                                   
                                              one-way ANOVA, Wang et al 2003  S4 Dauer Enriched, Wang                            
                                              et al 2003  S4 genes pass two-wayANOVA P0                                          

ZK470.5 Aff_ZK470.5 P W All gene names: nck-1; tag-22; ZK470.5; ZK470.5b.1; ZK470.5b.2; CE29645; CE31270; WBGene00006410; WP:CE29645; WP:CE31270; XE768 WormBase description: tag-22 encodes a protein with similarity to the human NCK adaptor protein 2 and orthologous to C.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, ViswanathanM et al 2005  S2                                  
                                              sir-2.1 regulated                                                                  

ZK520.4 Aff_ZK520.4 P W All gene names: cul-2; ZK520.4; ZK520.4b.1; ZK520.4b.2; 3O781; CE32774; CE32775; CE32776; CE36259; NM_067424; WBGene00000837; WP:CE32774; WP:CE32775; WP:CE32776; WP:CE36259 WormBase description: cul-2 encodes a member of the cullin family that affects embryonic viability and is required for cytokinesis and mitotic chromosome segregation; expressed embryonically in diverse cell types throughout larval development and in the adult germ line.
ZK593.4 Aff_ZK593.4 P W All gene names: rbp-2; rbr-2; ZK593.4; 4L691; CE35704; NM_069631; WBGene00004319; WP:CE35704 WormBase description: Human XE169 like
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph                                                                            

ZK637.14 Aff_ZK637.14 P W All gene names: ZK637.14; 3J978; CE00432; WBGene00014031; WP:CE00432 WormBase description: Zinc finger, C3HC4 type (RING finger)
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, mixed sperm soma,                              
                                              Reinke et al 2004, fem3 enriched genes, ViswanathanM et                            
                                              al 2005  S2 sir-2.1 regulated                                                      

ZK899.8 Aff_C07B5.1 P W All gene names: GAP-2-4; gap-2; ZK899.8; ZK899.8i.1; ZK899.8i.2; CE23470; CE23471; CE23472; CE23473; CE23474; CE23475; CE28277; CE31677; CE39119; NM_077193; WBGene00001516; WP:CE23470; WP:CE23471; WP:CE23472; WP:CE23473; WP:CE23474; WP:CE23475; WP:CE28277; WP:CE31677; WP:CE39119; XK133 WormBase description: gap-2 encodes a Ras GTPase-activating protein (RasGAP) that is orthologous to mammalian nGAP and synGAP (OMIM:606136, OMIM:603384, synGAP is essential for postnatal survival and neuronal development); by homology, GAP-2 is predicted to function as a negative regulator of Ras signaling by enhancing the intrinsically weak Ras GTPase activity; gap-2 loss-of-function mutations partially suppress the larval lethality of let-23 and let-60 loss-of-function mutations, supporting a role for gap-2 in negative regulation of Ras signaling in vivo; gap-2 can encode at least eight different isoforms that appear to be expressed in a wide variety of tissues including the vulva, gonad, pharynx, neurons, and blast/rectal cells of the tail.
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, mixed oogenesis soma,                                    
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated