Hill et al 2000, developmentally modulated cluster, 84 genes Gene list file name: Hill2000_T1_cluster5-2.txt Type of gene identifier: Affymetrix custom chip Description: Hill et al 2000, Supplymental Dataset, developmentally modulated genes cluster(5,2) Organism: Caenorhabditis elegans (nematode) Gene list type: Experimental Gene name Source Gene ID All gene names WormBase description WormBase CDS description Proteome description Member of lists (Publications) Other annotations Aff_DAP5 Aff_DAP5 B0410.2 Aff_B0410.2 vang-1; B0410.2; CE06708; CE27572; NM_076099; NM_076100; WBGene00015171; WP:CE06708; WP:CE27572; XD507 ViswanathanM et al 2005 S2 sir-2.1 regulated, ViswanathanM et al 2005 S2 daf-16 Resveratrol B0495.6 Aff_B0495.6 B0495.6; 2H988; CE01764; WBGene00015205; WP:CE01764 ViswanathanM et al 2005 S2 sir-2.1 regulated B0546.2 Aff_B0546.2 B0546.2; B0546.2.1; B0546.2.2; 4E138; CE30591; WBGene00015249; WP:CE30591 McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated C02B10.4 Aff_C02B10.4 C02B10.4; C02B10.4.1; C02B10.4.2; 4F857; CE16801; WBGene00015329; WP:CE16801 Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, GO categories, ViswanathanM et al 2005 S2 sir-2.1 regulated C05C8.4 Aff_C05C8.4 gei-6; C05C8.4; 5H708; CE07922; NM_072435; WBGene00001563; WP:CE07922 Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, wt herm vs wt male enriched gen, ViswanathanM et al 2005 S2 sir-2.1 regulated, ViswanathanM et al 2005 S2 daf-16 Resveratrol C06G3.9 Aff_C06G3.9 C06G3.9; C06G3.9.1; C06G3.9.2; 4H798; CE07985; WBGene00015555; WP:CE07985 McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, wt herm vs wt male enriched gen C09H10.6 Aff_C09H10.6 C09H10.6; 2L397; CE03007; WBGene00007500; WP:CE03007 histone binding protein Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 daf-16 Resveratrol, ViswanathanM et al 2005 S2 sir-2.1 regulated C13F10.7 Aff_C13F10.7 C13F10.7; 5H702; CE08148; WBGene00015746; WP:CE08148 Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, GO categories, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated C14B9.4 Aff_C14B9.4 plk-1; C14B9.4; C14B9.4a.1; C14B9.4a.2; 3J193; CE26649; CE30602; WBGene00004042; WP:CE26649; WP:CE30602; plc1 plk-1 encodes a serine/threonine polo-like kinase homologous to Drosophila polo and Saccharomyces cerevisiae CDC5; PLK-1 is required for meiotic nuclear envelope breakdown, polar body formation and extrusion, and proper chromosome segregation during meiosis, and additionally, may play a role in germline development; PLK-1 is proposed to phosphorylate REC-8, a meiotic-specific cohesin, thus promoting REC-8 degradation and subsequent separation of sister chromatids; PLK-1 is localized diffusely in the cytoplasm of mature oocytes, but during meiosis I becomes associated with pre-metaphase chromatin and then at anaphase with chromatin and the area between dividing chromatin; in embryos, PLK-1 localizes to centrosomes, metaphase chromatin, and during telophase, to the area between dividing chromatin. Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, Fig2b shared gemlines, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt males vs glp4 male enriched , Reinke et al 2004, wt herm vs wt male enriched gen, ViswanathanM et al 2005 S2 sir-2.1 regulated C17E4.10 Aff_C17E4.10 C17E4.10; 1K15; CE32589; WBGene00007647; WP:CE32589 Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated C25D7.3 Aff_C25D7.3 dpy-29; sdc-3; C25D7.3; 5P520; CE08389; NM_074302; WBGene00004747; WP:CE08389 sdc-3 encodes a protein that contains two mutationally separable domains: a zinc finger motif required for dosage compensation and a myosin- like putative ATP- binding region required for her-1 regulation of sex determination; SDC-3 activates dosage compensation by directing the dosage compensation protein complex to the hermaphrodite X chromosomes, and is functionally redundant with SDC-2 with respect to dosage compensation; SDC-1, SDC-2, and SDC-3 proteins form a complex. Zinc finger, C2H2 type Lund et al 2002 Fig3D Oocyte-en, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, mixed oogenesis soma C26E6.4 Aff_C26E6.4 phi-14; rpb-2; C26E6.4; 3G33; CE01162; NM_065646; WBGene00016140; WP:CE01162 DNA-directed RNA polymerase II McCarroll et al 2004 SFig5 conserved w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated C30A5.3 Aff_C30A5.3 C30A5.3; C30A5.3.1; C30A5.3.2; 3J315; CE32154; WBGene00016238; WP:CE32154 McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated C32D5.11 Aff_C32D5.11 C32D5.11; 2G644; CE02527; WBGene00016318; WP:CE02527 Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 daf-16 Resveratrol C34E11.1 Aff_C34E11.1 rsd-3; C34E11.1; C34E11.1.1; C34E11.1.2; CE03062; NM_077572; WBGene00004682; WP:CE03062; XM421 yeast hypothetical L8167.6 like McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, list of genes in cluster A, Reinke et al 2004, list of genes in cluster order, ViswanathanM et al 2005 S2 sir-2.1 regulated C36B1.12 Aff_C36B1.12 imp-1; C36B1.12; C36B1.12a.1; C36B1.12a.2; C36B1.12c.1; C36B1.12c.2; 1J331; CE05379; CE38290; CE38291; WBGene00007979; WP:CE05379; WP:CE38290; WP:CE38291 McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 daf-16 Resveratrol, ViswanathanM et al 2005 S2 sir-2.1 regulated C38C10.5 Aff_C38C10.5 mdt-14; rgr-1; C38C10.5; 3K493; CE34528; CE34529; NM_066666; NM_066667; WBGene00004343; WP:CE34528; WP:CE34529 RGR1 (yeast) Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, mixed oogenesis soma, ViswanathanM et al 2005 S2 sir-2.1 regulated C43E11.10 Aff_C43E11.10 cdc-6; C43E11.10; 1E838; CE08688; NM_058942; WBGene00000382; WP:CE08688 cdc-6 encodes a homolog of an origin complex component (CDC6) which in yeast controls the start of DNA replication, and also has a distant paralog (Y39A1A.12) within the C. elegans genome; CDC-6 is superficially dispensable for embryonic viability, perhaps because of redundancy with Y39A1A.12. McCarroll et al 2004 SFig5 conserved w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, GO categories, ViswanathanM et al 2005 S2 sir-2.1 regulated C44B9.3 Aff_C44B9.3 C44B9.3; 3L966; CE05405; WBGene00008080; WP:CE05405 Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated C47D12.2 Aff_C47D12.2 C47D12.2; C47D12.2.1; C47D12.2.2; 2L967; CE20567; WBGene00008136; WP:CE20567 C47D12.2 encodes an ortholog of human FLJ20071/FLJ90130 (dymeclin, OMIM:607461, mutated in Dyggve-Melchior-Clausen dysplasia and Smith-McCort dysplasia), which has no obvious function in mass RNAi assays McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, intrinsic, Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, ViswanathanM et al 2005 S2 sir-2.1 regulated C47G2.5 Aff_C47G2.5 C47G2.5; C47G2.5.1; C47G2.5.2; 2L591; CE38162; WBGene00008166; WP:CE38162 McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, mixed oogenesis soma C50C3.8 Aff_C50C3.8 bath-42; C50C3.8; C50C3.8.1; C50C3.8.2; 3J252; CE00124; WBGene00016803; WP:CE00124 The C50C3.8 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis. Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated C54G10.2 Aff_C54G10.2 rfc-1; C54G10.2; 5P124; CE20613; NM_074218; WBGene00004337; WP:CE20613 replication factor C 140 KD subunit like McCarroll et al 2004 SFig5 conserved w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, intrinsic, Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, wt herm vs wt male enriched gen D1054.15 Aff_D1054.15 phi-13; tag-135; D1054.15; D1054.15.1; D1054.15.2; 5L288; CE05533; WBGene00006481; WP:CE05533 beta transducin like protein McCarroll et al 2004 SFig5 conserved w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen DY3.7 Aff_DY3.7 sup-17; DY3.7; 1J373; CE15751; NM_059976; WBGene00006324; WP:CE15751 sup-17 encodes an ADAM protein, an integral membrane disintegrin and zinc-activated metalloproteinase, orthologous to Drosophila and mouse KUZBANIAN and the vertebrate ADAM10 proteins; SUP-17 is required maternally for embryonic development and plays a role in LIN-12/Notch-mediated cell signaling required for several cell fate decisions during vulval development; SUP-17 is also required for normal body morphology and male tail development; SUP-17 functions cell autonomously to facilitate LIN-12 signaling and requires the LIN-12 extracellular domain to do so. Zinc-binding metalloprotease domain McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, list of genes in cluster E EEED8.4 Aff_EEED8.4 EEED8.4; 2F699; CE39716; WBGene00017135; WP:CE39716 Probable RNA binding protein F07A11.2 Aff_F07A11.2 F07A11.2; F07A11.2b.1; F07A11.2b.2; F07A11.2b.3; 2L884; CE03144; CE27915; WBGene00008546; WP:CE03144; WP:CE27915 glucosamine-fructose-6-phosphate aminotransferase McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, IVb male soma enriched genes F09G2.8 Aff_F09G2.8 F09G2.8; F09G2.8.1; F09G2.8.2; 5H670; CE09303; WBGene00017316; WP:CE09303 Lund et al 2002 Fig3D Oocyte-en, McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, GO categories, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated F14F3.2 Aff_F14F3.2 F14F3.2; CE31478; WBGene00008805; WP:CE31478; XL145 ankyrin motif McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated, Wang et al 2003 S4 Early genes, Wang et al 2003 S3 genes pass one-way ANOVA, Wang et al 2003 S4 genes pass two-wayANOVA P0 F20D1.6 Aff_F20D1.6 rbg-1; F20D1.6; CE09499; NM_078089; WBGene00004317; WP:CE09499; XP605 Human mRNA KIAA0066 predicted protein like McCarroll et al 2004 SFig1-4 conserved w/ Drosoph F26F12.3 Aff_F26F12.3 F26F12.3; F26F12.3a.1; F26F12.3a.2; F26F12.3c.1; F26F12.3c.2; 5G320; CE20728; CE36538; CE37765; WBGene00017834; WP:CE20728; WP:CE36538; WP:CE37765 ViswanathanM et al 2005 S2 sir-2.1 regulated F31C3.5 Aff_F31C3.5 F31C3.5; 1P647; CE17734; WBGene00009287; WP:CE17734 McCarroll et al 2004 SFig5 conserved w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated F33C8.1 Aff_F33C8.1 tag-53; F33C8.1; CE32400; CE32401; WBGene00006432; WP:CE32400; WP:CE32401; XP337 tag-53 encodes a protein with high similarity to human Attractin, and affects fertility and locomotion. McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, list of genes in cluster B F38H4.7 Aff_F38H4.7 tag-30; F38H4.7; F38H4.7.1; F38H4.7.2; CE17807; NM_069843; WBGene00006415; WP:CE17807 BTB (also known as BR-C/Ttk) domain. McCarroll et al 2004 SFig1-4 conserved w/ Drosoph F39B2.4 Aff_F39B2.4 mdt-23; sur-2; F39B2.4; 1P370; CE28023; CE28024; NM_061174; WBGene00006349; WP:CE28023; WP:CE28024 SUR-2 PROTEIN Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, mixed oogenesis soma, ViswanathanM et al 2005 S2 sir-2.1 regulated F40F8.5 Aff_F40F8.5 F40F8.5; 2L424; CE32888; WBGene00009578; WP:CE32888 Lund et al 2002 Fig3C Germline-intrinsic, Reinke et al 2004, intrinsic, Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, GO categories, ViswanathanM et al 2005 S2 sir-2.1 regulated F44A2.1 Aff_F44A2.1 tag-153; F44A2.1; 5J807; CE04568; CE27382; WBGene00006499; WBGene00018401; WP:CE04568; WP:CE27382 Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, ViswanathanM et al 2005 S2 sir-2.1 regulated, ViswanathanM et al 2005 S2 daf-16 Resveratrol F47A4.2 Aff_F47A4.2 dpy-22; mdt-12; psa-6; sop-1; F47A4.2; CE16058; NM_077244; WBGene00001081; WP:CE16058; XK430 dpy-22 encodes a broadly expressed protein, homologous to the human transcriptional mediator protein TRAP230, which is involved in WNT and RAS signaling, as well as in dosage compensation; DPY-22 has a C-terminal glutamine-rich domain that is dispensable for inhibition of RAS-dependent cell differentiation, but is required for inhibition of BAR-1-dependent gene expression. Reinke et al 2004, wt herm vs wt male enriched gen F53G12.5 Aff_F53G12.5 mex-3; F53G12.5; F53G12.5a.1; F53G12.5a.2; 1A607; CE11014; CE25000; NM_058280; WBGene00003229; WP:CE11014; WP:CE25000 mex-3 encodes two KH domain-containing RNA binding proteins; in the early embryo, maternally provided MEX-3 is required for specifying the identities of the anterior AB blastomere and its descendants, as well as for the identity of the P3 blastomere and proper segregation of the germline P granules; mex-3 mRNA is distributed uniformly in the syncytial core of the adult distal gonad, mature oocytes, and early 1-cell stage embryos, but then becomes more prominent in the AB blastomere and its daughters by the 4-cell stage after which it is rapidly degraded save for the D and P4 blastomeres; MEX-3 protein is also detected uniformly in the cytoplasm of oocytes and 1-cell stage embryos, but like the mRNA, becomes more abundant in AB and its daughters at the 2- and 4-cell stages, respectively, before disappearing; MEX-3 is also detected in association with P granules from the 2-cell stage until the late stages of embryogenesis. McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, ViswanathanM et al 2005 S2 sir-2.1 regulated F54C8.4 Aff_F54C8.4 F54C8.4; 3K532; CE00190; WBGene00010037; WP:CE00190 Protein-tyrosine phosphatase Lund et al 2002 Fig3D Oocyte-en, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, GO categories, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated F55A11.3 Aff_F55A11.3 F55A11.3; F55A11.3.1; F55A11.3.2; 5M249; CE05945; WBGene00010076; WP:CE05945 Zinc finger, C3HC4 type (RING finger) McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, list of genes in cluster order, ViswanathanM et al 2005 S2 sir-2.1 regulated F55A3.3 Aff_F55A3.3 phi-16; F55A3.3; 1L369; CE17113; WBGene00018849; WP:CE17113 transcritpion factor McCarroll et al 2004 SFig5 conserved w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, list of genes in cluster order, ViswanathanM et al 2005 S2 sir-2.1 regulated F58A4.8 Aff_F58A4.8 sas-3; tbg-1; F58A4.8; F58A4.8.1; F58A4.8.2; 3K716; CE00224; NM_066730; TUBG; WBGene00006540; WP:CE00224 tbg-1 encodes gamma-tubulin; in C. elegans, tbg-1 activity is essential and is required for normal bipolar spindle assembly and function, as well as the fast phase of female pronuclear migration following fertilization; while tbg-1 is required for proper organization and function of kinetochore and interpolar microtubules, it does not appear to be absolutely required for microtubule nucleation and growth; TBG-1 localizes to centrosomes in both interphase and mitotic cells, exhibiting a dynamic behavior during mitosis that differs between anterior and posterior centrosomes. Gamma-like tubulin McCarroll et al 2004 SFig5 conserved w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated K03B4.3 Aff_K03B4.3 TAF-11; taf-10; K03B4.3; 5F167; CE07323; CE28580; NM_071859; NM_071860; WBGene00006392; WP:CE07323; WP:CE28580 McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Romagnolo et al 2002 Fig3b others, ViswanathanM et al 2005 S2 sir-2.1 regulated K04D7.5 Aff_K04D7.5 gon-4; K04D7.5; 4K967; CE35579; NM_069463; WBGene00001653; WP:CE35579 gon-4 encodes a large (1336-residue), unfamiliar, acidic (20% acidic residues and pI of 4.4), nuclear protein directly required for gonadogenesis in both sexes and, indirectly, for proper germ line and vulval development; gon-4 is expressed (and functionally required) in somatic gonadal cells during early gonadal development; while Z1 and Z4 (the somatic gonad precursor cells) appear to be specified correctly in gon-4 mutant L1 larvae, and other postembryonic events in somatic gonadal development appear to still occur at normal times, the postembryonic cell divisions of Z1 and Z4 are greatly delayed or missing in gon-4 larvae; GON-4 is subtly similar to human HCCA2 (OMIM:607860, expression associated with hepatocellular carcinoma). Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated K07A1.2 Aff_K07A1.2 K07A1.2; K07A1.2.1; K07A1.2.2; K07A1.2.3; 1K163; CE18855; WBGene00010609; WP:CE18855 This gene encodes a protein predicted by Eisenberg and coworkers, with 52% accuracy, to be mitochondrial. deoxyuridine 5'-triphosphate nucleotidohydrolase Lund et al 2002 Fig3D Oocyte-en, McCarroll et al 2004 SFig5 conserved w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated K07C11.2 Aff_K07C11.2 air-1; let-412; K07C11.2; K07C11.2.1; K07C11.2.2; 5I703; CE21025; NM_072718; WBGene00000098; WP:CE21025 AIR-1 belongs to the Aurora-A family of serine/threonine kinases that localize to centrosomes; AIR-1 is required for embryonic survival, germline proliferation and development, locomotion, and vulval development; AIR-1 is required to recruit centrosomal gamma-tubulin during maturation; Aurora-A kinases are implicated in centrosome separation and spindle assembly. protein kinase McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, intrinsic, Reinke et al 2004, Fig2b shared gemlines, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, wt males vs glp4 male enriched , Reinke et al 2004, list of genes in cluster E K08E7.1 Aff_K08E7.1 K08E7.1; CE11920; NM_070004; WBGene00010671; WP:CE11920 McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, oogenesis enriched genes K10C3.6 Aff_K10C3.6 nhr-49; K10C3.6; K10C3.6b.1; K10C3.6b.2; K10C3.6c.1; K10C3.6c.2; 1K449; CE12084; CE28943; CE32693; CE32694; NM_060211; NM_060212; NM_181998; NM_181999; WBGene00003639; WP:CE12084; WP:CE28943; WP:CE32693; WP:CE32694 Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains) M05B5.5 Aff_M05B5.5 hlh-2; M05B5.5; M05B5.5a.1; M05B5.5a.2; 1H768; CE06191; NM_059633; WBGene00001949; WP:CE06191 hlh-2 encodes a Class I basic helix-loop-helix (bHLH) transcription factor that is the C. elegans ortholog of the mammalian E and Drosophila Daughterless transcriptional activators; HLH-2 activity is required for cell fate specifications occuring during embryonic and larval development that affect such processes as gonadogenesis, male tail formation, and programmed cell death; HLH-2 has been shown to dimerize with at least two C. elegans Acheate-scute homologs, LIN-32, a neural-specific protein with which it functions in male tail development and HLH-3, with which it is coexpressed in the nuclei of embryonic neuronal prescursors and with which it regulates the transcription of the EGL-1 cell death activator in the NSM sister cells; in gonadogenesis, HLH-2 is required for bestowing proAC competence on the cells that undergo the AC/VU (anchor cell/ventral uterine precursor) cell fate decision, for specification, differentiation, and function of the distal tip cell (DTC) and AC, including transcriptional regulation of the LAG-2 Delta-like ligand in the latter, and for formation of the uterine seam cell (utse); genetic analysis also suggests that HLH-2 functions with HLH-14, an additional Acaete-scute homolog, to specify the PVQ/HSN/PHB neuroblast cell lineage; HLH-2 is expressed in all nuclei of early embryos until the ~200-cell stage, when expression becomes increasingly restricted to neuronal cells and their immediate precursors; later expression is detected in, but not limited to, pharyngeal cells, anterior neurons, vulval and uterine muscles, the DTCs, the presumptive and mature AC, the Q neuroblast, and enteric muscles; comparative analysis of transcriptional and translational reporters indicates that hlh-2 is expressed in both the anchor cell and the ventral uterine (VU) precursor, but that expression in the latter is subject to post-transcriptional down-regulation; HLH-2 accumulation in the presumptive AC is the first detectable difference between the AC and VU precursors during the lateral specification event that distinguishes these two cell fates. transcription factor E2-A like McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated R01H2.6 Aff_R01H2.6 ubc-18; R01H2.6; 3I158; CE25067; NM_066140; WBGene00006713; WP:CE25067 ubc-18 encodes an E2 ubiquitin-conjugating enzyme related to human UBCH7 (OMIM:603731); UBC-18 activity is required for normal growth and reproduction, and UBC-18 functions redundantly with LIN-35/Rb and other class B synthetic multivulval (SynMuv) gene products to regulate pharyngeal morphogenesis during embryonic development; ubc-18 transcripts are detected in the germline, embryos, late larval stages, and adults, suggesting that UBC-18 may function maternally to regulate several aspects of C. elegans development; the substrates of UBC-18 are not yet known. McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, GO categories, ViswanathanM et al 2005 S2 sir-2.1 regulated R04F11.3 Aff_R04F11.3 R04F11.3; R04F11.3.1; R04F11.3.2; 5M796; CE29598; WBGene00011016; WP:CE29598 Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, list of genes in cluster E, Romagnolo et al 2002 Fig3b Unkown, ViswanathanM et al 2005 S2 sir-2.1 regulated R05H5.3 Aff_R05H5.3 R05H5.3; 2K489; CE02290; WBGene00011038; WP:CE02290 thioredoxin Golden et al 2004, N2 vs daf-2 different genes at , Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, GO categories, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated R09A1.1 Aff_R09A1.1 R09A1.1; 5B495; CE30106; WBGene00019971; WP:CE30106 Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes R13G10.1 Aff_R13G10.1 dpy-27; R13G10.1; 3E904; CE01052; NM_065370; WBGene00001086; WP:CE01052 dpy-27 encodes an ATP-binding protein that is a homolog of the SMC4 subunit of mitotic condensin; DPY-27, in combination with other proteins including MIX-1, act as a unit to repress X-linked gene expression during hermaphrodite dosage compensation; in XX oocytes and early embryos, DPY-27 exhibits diffuse nuclear localization, but by the 30-cell stage of embryogenesis, DPY-27 specifically localizes to X chromosomes; in XO animals at all stages, DPY-27 remains diffusely nuclear; the sex-specific localization of DPY-27 to X chromosomes is dependent upon wild-type activity of xol-1, as DPY-27 mislocalizes to the X chromosome of XO embryos in a xol-1 mutant background. chromosome segregation protein (SMC-1) Reinke et al 2004, list of genes in cluster order, ViswanathanM et al 2005 S2 daf-16 Resveratrol T01G9.4 Aff_T01G9.4 kup-2; npp-2; T01G9.4; 1I868; CE06341; NM_059855; WBGene00003788; WP:CE06341 npp-2 encodes a protein with low similarity to rat nucleoporin Nup75 that affects embryonic viability and has a variety of other defects in RNAi screens including: nuclear morphology, growth, fertility, locomotion, and egg laying; enriched in oocytes. Jones et al 2001 Non dauer genes P<0.05, McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, ViswanathanM et al 2005 S2 sir-2.1 regulated T05H4.14 Aff_T05H4.14 gad-1; tag-86; T05H4.14; 5G912; CE13295; NM_072234; WBGene00001513; WP:CE13295 The gad-1 gene encodes a WD repeat-containing protein that is required maternally for gastrulation initiation during early embryogenesis by regulating the division timing, spindle orientation, and subsequent inward migration of the two gut precusor (E) cells at the 26-cell stage. McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated T06E6.2 Aff_T06E6.2 cyb-2; cyb-3; T06E6.2; T06E6.2a.1; T06E6.2a.2; 5P877; CE13315; CE27776; NM_074424; WBGene00000868; WP:CE13315; WP:CE27776 cyb-3 encodes a member of the cyclin B family that is required for embryonic viability, and may be involved with sister chromatid segregation. Jiang et al 2001 Fig2 cyclin-genes, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, Fig2b shared gemlines, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt males vs glp4 male enriched , Reinke et al 2004, wt herm vs wt male enriched gen, ViswanathanM et al 2005 S2 sir-2.1 regulated T08B2.5 Aff_T08B2.5 T08B2.5; 1G795; CE13429; CE25984; CE26949; CE30298; CE33171; CE33172; CE38728; WBGene00020346; WP:CE13429; WP:CE25984; WP:CE26949; WP:CE30298; WP:CE33171; WP:CE33172; WP:CE38728 ViswanathanM et al 2005 S2 sir-2.1 regulated T10B5.6 Aff_T10B5.6 knl-3; T10B5.6; 5C349; CE18236; NM_071119; WBGene00020392; WP:CE18236 Reinke et al 2004, Fig2b shared gemlines, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt males vs glp4 male enriched , Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 daf-16 Resveratrol, ViswanathanM et al 2005 S2 sir-2.1 regulated T12D8.7 Aff_T12D8.7 taf-9; T12D8.7; 3O715; CE16404; NM_067413; WBGene00006391; WP:CE16404 McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, mixed oogenesis soma, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, GO categories, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated T18D3.1 Aff_T18D3.1 T18D3.1; CE03662; WBGene00011820; WP:CE03662; XN75 ViswanathanM et al 2005 S2 sir-2.1 regulated T20F5.6 Aff_T20F5.6 T20F5.6; T20F5.6.1; T20F5.6.2; 1E490; CE28685; WBGene00020628; WP:CE28685 zinc finger protein Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, ViswanathanM et al 2005 S2 sir-2.1 regulated T22C1.1 Aff_T22C1.1 T22C1.1; 1I513; CE36611; WBGene00011912; WP:CE36611 McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated T22C1.4 Aff_T22C1.4 T22C1.4; 1I516; CE06492; WBGene00011915; WP:CE06492 T23G7.1 Aff_T23G7.1 dpl-1; mex-4; T23G7.1; 2J461; CE21197; NM_063556; WBGene00001061; WP:CE21197 dpl-1 encodes a homolog of mammalian DP required for embryonic asymmetry. transcription factor DP-1 Jiang et al 2001 Fig1 hermaphrodite-enriched TF, McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated T26A5.7 Aff_T26A5.7 set-1; T26A5.7; T26A5.7b.1; T26A5.7b.2; 3H540; CE19602; CE34599; WBGene00004781; WP:CE19602; WP:CE34599 McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated W03D2.4 Aff_W03D2.4 pcn-1; W03D2.4; W03D2.4.1; W03D2.4.2; 4E812; CE37726; NM_068065; WBGene00003955; WP:CE37726 pcn-1 encodes the C. elegans ortholog of proliferating cell nuclear antigen (PCNA), an acidic protein that is an essential component of the DNA replication and repair machinery and serves as a processivity factor for DNA polymerase delta; PCN-1 is required for early embryogenesis and for proper germ-line development, and directly interacts with CKI-2, a cyclin-dependent kinase inhibitor homolog that may be required for cell cycle progression during embryogenesis, and with ATL-1/PI3K, KIN-20, MRT-2/RAD1, and RFC-1, proteins that all play a role in the DNA damage checkpoint pathway; PCN-1 is highly expressed in ovaries and developing embryos. cyclin McCarroll et al 2004 SFig5 conserved w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Murphy et al 2003 Fig2 Class2 shorten lifespan, Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, Fig2b shared gemlines, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt males vs glp4 male enriched , Reinke et al 2004, wt herm vs wt male enriched gen, ViswanathanM et al 2005 S2 sir-2.1 regulated W04D2.4 Aff_W04D2.4 W04D2.4; 5M976; CE06541; WBGene00012243; WP:CE06541 Zinc finger, C2H2 type Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, GO categories, ViswanathanM et al 2005 S2 sir-2.1 regulated W06H3.2 Aff_W06H3.2 pus-1; W06H3.2; 5R274; CE20158; NM_074841; WBGene00004248; WP:CE20158 pus-1 encodes a putative tRNA pseudouridine synthase that is predicted, by phylogenetic profiling, to be mitochondrial. McCarroll et al 2004 SFig5 conserved w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen Y106G6H.15 Aff_Y106G6H.15 Y106G6H.15; 1L50; CE20424; WBGene00013725; WP:CE20424 Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated Y43F4B.6 Aff_Y43F4B.6 klp-19; Y43F4B.6; 3O392; CE16631; NM_067341; WBGene00002229; WP:CE16631 klp-19 encodes a plus-end-directed microtubule motor protein that is most closely related to motors of the kinesin-4 family; KLP-19 activity is essential for embryonic and larval development and is required for generating a force that aligns sister chromatid kinetochores directly opposite the spindle poles thus ensuring proper holocentric chromosome segregation; KLP-19 expression is detected in embryos and in the gonad, where it is most strongly expressed in distal mitotic nuclei and in late meiotic prophase nucleoplasm; during meiosis and mitosis, KLP-19 expression is dynamic and is detected in the nucleoplasm, the spindle body, in association with condensed chromosomes (particularly between homologous chromosomes), and in the spindle interzone. Kinesin motor domain McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, intrinsic, Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, GO categories Y47D3A.26 Aff_Y47D3A.AA smc-3; Y47D3A.26; 3M395; CE37287; NM_067052; WBGene00004873; WP:CE37287 McCarroll et al 2004 SFig5 conserved w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, GO categories Y47G6A.8 Aff_Y47G6A_247.I crn-1; Y47G6A.8; 1E51; CE22109; NM_058767; WBGene00000794; WP:CE22109 endonuclease McCarroll et al 2004 SFig5 conserved w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, GO categories, ViswanathanM et al 2005 S2 sir-2.1 regulated Y49E10.19 Aff_Y49E10.S ani-1; Y49E10.19; Y49E10.S; 3N536; CE33878; NM_067223; WBGene00013038; WP:CE33878 PH (pleckstrin homology) domain McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, herm sperm, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, spermatogenesis enriched genes, Reinke et al 2004, herm soma enriched genes, Reinke et al 2004, fem3 enriched genes Y57E12AL.5 Aff_Y57E12_247.D let-425; mdt-6; med-6; Y57E12AL.5; Y57E12_247.D; 5H538; CE25510; NM_072390; WBGene00003164; WP:CE25510 mdt-6 encodes a highly conserved transcriptional mediator of the Med6 family that includes Saccharomyces cerevisiae Med6 and human MED6 (OMIM:602984); MDT-6 is an essential gene required maternally for embryogenesis and zygotically for postembryonic transcriptional regulation of genes involved in the Ras and Wnt signaling pathways that mediate vulval and male tail formation, respectively; mdt-6 is expressed in all cells at all stages and localizes to the peripheral region of nuclei, where actively transcribed portions of the genome may be localized. McCarroll et al 2004 SFig1-4 conserved w/ Drosoph Y75B8A.17 Aff_Y75B8A.T gmn-1; Y75B8A.17; 3N314; CE23028; WBGene00013552; WP:CE23028 Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated Y87G2A.1 Aff_Y87G2A.F Y87G2A.1; 1O117; CE24681; WBGene00013593; WP:CE24681 Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, ViswanathanM et al 2005 S2 sir-2.1 regulated ZC168.4 Aff_ZC168.4 cyb-1; ZC168.4; ZC168.4.1; ZC168.4.2; ZC168.4.3; ZC168.4.4; 4L501; CE06570; NM_069586; WBGene00000865; WP:CE06570 cyb-1 encodes a cyclin B homolog that appears to be required both for embryogenesis (via maternally encoded CYB-1) and for postembryonic development and fertility (via zygotically encoded CYB-1); removing maternal product in cyb-1(RNAi) embryos causes multiple nuclei, and affected embryos arrest development at an early embryonic stage. cyclin Jiang et al 2001 Fig2 cyclin-genes, McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, IVb male soma enriched genes, ViswanathanM et al 2005 S2 sir-2.1 regulated, ViswanathanM et al 2005 S2 daf-16 Resveratrol ZK1128.5 Aff_ZK1128.5 ZK1128.5; 3L211; CE01687; WBGene00014231; WP:CE01687 The ZK1128.5 gene encodes a homolog of Swp73/BAF60, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; ZK1128.5 may be involved in asymmetric cell division of the T cells. D15Kz1 protein homolog McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, intrinsic, Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, wt herm vs wt male enriched gen, ViswanathanM et al 2005 S2 sir-2.1 regulated ZK507.6 Aff_ZK507.6 ZK507.6; 3K196; CE03820; WBGene00013981; WP:CE03820 G2/M Cyclin A McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated, ViswanathanM et al 2005 S2 daf-16 Resveratrol ZK632.1 Aff_ZK632.1 mcm-6; ZK632.1; 3J887; 3K887; CE00415; CE38018; NM_066769; WBGene00003158; WP:CE00415; WP:CE38018 mcm-6 encodes a protein that has similarity to human DNA replication licensing factor MCM6 and affects embryonic viability. McCarroll et al 2004 SFig5 conserved w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, list of genes in cluster F, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, ViswanathanM et al 2005 S2 sir-2.1 regulated ZK863.7 Aff_ZK863.7 rnp-1; ZK863.7; 5M673; CE15447; NM_073658; WBGene00004384; WP:CE15447 RNP-1 protein McCarroll et al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke et al 2004, wt vs glp-4 enriched genes, Reinke et al 2004, list of genes in cluster order, Reinke et al 2004, oogenesis enriched genes, Reinke et al 2004, wt herm vs wt male enriched gen, Reinke et al 2004, list of genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1 regulated