Hill et al 2000, developmentally modulated cluster, 177 genes

Gene list file name:Hill2000_T1_cluster6-2.txt
Type of gene identifier:Affymetrix custom chip
Description:Hill et al 2000, Supplymental Dataset, developmentally modulated genes cluster(6,2)  
Organism:Caenorhabditis elegans (nematode)
Gene list type:Experimental

Gene name             Source Gene ID          Annotation                                                  Date       Added by    

AFF_C16C2.1 Aff_C16C2.1 P W
AFF_K10C9.2 Aff_K10C9.2 P W
AFF_Y39B6.R Aff_Y39B6.R P W
AFF_Y39G10A_246.I Aff_Y39G10A_246.I P W
AFF_Y43F4B.7 Aff_Y43F4B.7 P W
AFF_Y75B8A.U Aff_Y75B8A.U P W
B0041.7 Aff_B0041.7 P W All gene names: slr-8; xnp-1; B0041.7; 1F234; CE17314; NM_059022; WBGene00006961; WP:CE17314 WormBase description: xnp-1 encodes an ATP-dependent DNA helicase of the SNF2 family that is orthologous to human XNP/ATR-X, which is associated with a number of X-linked mental retardation syndromes; in C. elegans, xnp-1 activity is required at high temperatures for embryogenesis, somatic gonad development, fertility, and vulval morphogenesis; in addition, animals doubly mutant for xnp-1 and lin-35/Rb, hpl-2/HP1, or nucleosome remodelling and histone deacetylase (NuRD) complex members such as lin-53 and let-418, display larval arrest with growth cessation but continued cell proliferation; xnp-1 is also required, with lin-35/Rb and hpl-2/HP1, for proper regulation of transgene expression; xnp-1 mRNA, detectable in embryos and the germline by in situ hybridization, is expressed at highest levels in embryos with decreasing levels seen in successive larval stages; xnp-1 transcriptional reporter fusions exhibit strong expression beginning at mid-embryogenesis but fading by embryonic morphogenesis; at hatching, expression is observed in all dividing cells including the P lineage, and at later larval stages expression is observed in the vulval precursor cells. WormBase CDS description: helicase
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph                                                               

B0238.11 Aff_B0238.11 P W All gene names: B0238.11; B0238.11.1; B0238.11.2; 5F747; CE07701; WBGene00015075; WP:CE07701
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, wt herm vs wt male enriched gen, Reinke et al                                
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated                                                         

B0281.5 Aff_B0281.5 P W All gene names: B0281.5; 2C588; CE07716; WBGene00015112; WP:CE07716
                                              
Member of lists (Publications lists):
                                              Jiang et al 2001 Fig1                                             
                                              hermaphrodite-enriched neuro, Jones et al 2001  Non                                
                                              dauer genes P<0.05, Murphy et al 2003  Fig2 Class2                                 
                                              shorten lifespan, Reinke et al 2004, list of genes in                              
                                              cluster order, Reinke et al 2004, intrinsic, Reinke et                             
                                              al 2004, wt vs glp-4 enriched genes, Reinke et al 2004,                            
                                              GO categories, Reinke et al 2004, list of genes in                                 
                                              cluster E, ViswanathanM et al 2005  S2 sir-2.1                                     
                                              regulated                                                                          

B0403.4 Aff_B0403.4 P W All gene names: tag-320; B0403.4; CE03880; WBGene00015168; WP:CE03880; XH686 WormBase description: This gene encodes a protein predicted by Eisenberg and coworkers, with 52% accuracy, to be mitochondrial. WormBase CDS description: protein disulfide-isomerase
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster order, Reinke et al 2004, list of genes in                              
                                              cluster C, Reinke et al 2004, wt herm vs wt herm                                   
                                              enriched gen, ViswanathanM et al 2005  S2 sir-2.1                                  
                                              regulated, Wang et al 2003  S5 genes common to feeding                             
                                              ANOVA, Wang et al 2003  S3  genes pass one-way ANOVA                               

B0464.2 Aff_B0464.2 P W All gene names: B0464.2; 3K585; CE20456; WBGene00007184; WP:CE20456 WormBase description: TPR Domain
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, list of genes in cluster F,                            
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs                             
                                              glp-4 enriched genes, Reinke et al 2004, wt herm vs wt                             
                                              male enriched gen, ViswanathanM et al 2005  S2 daf-16                              
                                              Resveratrol, ViswanathanM et al 2005  S2 sir-2.1                                   
                                              regulated                                                                          

B0511.1 Aff_B0511.1 P W All gene names: fkb-7; B0511.1; 1L245; CE26851; NM_060391; WBGene00001432; WP:CE26851 WormBase description: fkb-7 encodes a peptidylprolyl cis/trans isomerase homologous to mammalian FK506-binding proteins; by homology, FKB-7 could function in a number of different processes including protein folding, signal transduction, and regulation of muscle contraction; however, as loss of fkb-7 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of FKB-7 in C. elegans development and/or behavior is not yet known.
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster A, Reinke et al 2004, list of genes in cluster                             
                                              order, ViswanathanM et al 2005  S2 sir-2.1 regulated                               

B0511.6 Aff_B0511.6 P W All gene names: B0511.6; B0511.6.1; B0511.6.2; 1L203; CE26853; WBGene00015232; WP:CE26853 WormBase description: helicase
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, wt herm vs wt male enriched                            
                                              gen, ViswanathanM et al 2005  S2 sir-2.1 regulated                                 

C01H6.7 Aff_C01H6.7 P W All gene names: tag-298; C01H6.7; 1H803; CE05190; WBGene00007256; WP:CE05190 WormBase description: Bromodomain
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt herm vs wt male enriched gen, Reinke et al                             
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated                                                         

C02E11.1 Aff_C02E11.1 P W All gene names: C02E11.1; C02E11.1a.1; C02E11.1a.2; 5B508; CE28528; CE32040; WBGene00015344; WP:CE28528; WP:CE32040
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Dauer specific genes                            
                                              P<0.05, McCarroll et al 2004  SFig1-4 conserved w/                                 
                                              Drosoph, Reinke et al 2004, list of genes in cluster                               
                                              order, Reinke et al 2004, list of genes in cluster C,                              
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated, Wang et                             
                                              al 2003  S5 genes common to feeding ANOVA, Wang et al                              
                                              2003  S3  genes pass one-way ANOVA, Wang et al 2003  S8                            
                                              SAGE genes in the dauer exit, Wang et al 2003  S7 SAGE                             
                                              genes in the dataset                                                               

C03D6.8 Aff_C03D6.8 P W All gene names: rpl-24.2; C03D6.8; C03D6.8.1; C03D6.8.2; 1K245; CE05202; NM_060171; WBGene00004437; WP:CE05202 WormBase description: rpl-24.2 encodes a large ribosomal subunit L24 protein paralog; its orthologs include ribosomal protein L30 isologs from mammals and 'Ribosomal Like Protein 24' (Rlp24p) from S. cerevisiae; it therefore appears to actually represent an ancient paralogy between two varieties of eukaryotic L24 protein. WormBase CDS description: ribosomal protein
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Wang et al 2003  S5 genes common to feeding                               
                                              ANOVA, Wang et al 2003  S3  genes pass one-way ANOVA                               

C04F6.4 Aff_C04F6.4 P W All gene names: unc-78; C04F6.4; C04F6.4b.1; C04F6.4b.2; CE03924; CE33554; NM_076189; WBGene00006810; WP:CE03924; WP:CE33554; XE28 WormBase description: The unc-78 gene encodes a homolog of actin-interacting protein 1 (AIP1) that regulates the ordered assembly of actin and cofilin in myofibrils.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, Wang et al 2003  S5 genes common to feeding                              
                                              ANOVA, Wang et al 2003  S3  genes pass one-way ANOVA                               

C04F6.5 Aff_C04F6.5 P W All gene names: dhs-27; C04F6.5; CE37079; NM_076190; WBGene00000990; WP:CE37079; XE32 WormBase description: dhs-27 encodes a short-chain dehydrogenase predicted to be mitochondrial. WormBase CDS description: alcohol/ribitol dehydrogenase
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 daf-16                                
                                              Resveratrol                                                                        

C05B5.4 Aff_C05B5.4 P W All gene names: C05B5.4; 3L81; CE00880; WBGene00007321; WP:CE00880
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

C07A12.7 Aff_C07A12.7 P W All gene names: C07A12.7; C07A12.7a.1; C07A12.7a.2; C07A12.7c.1; C07A12.7c.2; CE25764; CE27055; CE33557; WBGene00015561; WP:CE25764; WP:CE27055; WP:CE33557; XF138
C09G4.3 Aff_C09G4.3 P W All gene names: cks-1; dom-6; C09G4.3; 4J279; CE03980; NM_069056; WBGene00001051; WP:CE03980 WormBase description: A homolog of Cks/Suc1, a highly conserved member of the eukaryotic cell cycle machinery that affects both meiosis and mitosis and has a role in the inactivation of the M-phase promoting factor (MPF) during early embryogenesis. WormBase CDS description: cyclin-dependent kinase regulatory subunit
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt herm vs wt male enriched gen, Reinke et al                             
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated                                                         

C10C6.6 Aff_C10C6.6 P W All gene names: C10C6.6; 4M238; CE30858; WBGene00007514; WP:CE30858 WormBase description: E1-E2 ATPase
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, wt herm vs wt male enriched                            
                                              gen, ViswanathanM et al 2005  S2 sir-2.1 regulated,                                
                                              ViswanathanM et al 2005  S2 daf-16 Resveratrol,                                    
                                              ViswanathanM et al 2005 S2 Resveratrol regulate WT                                 

C10G11.7 Aff_C10G11.7 P W All gene names: C10G11.7; C10G11.7.1; C10G11.7.2; C10G11.7.3; 1G865; CE08086; WBGene00015687; WP:CE08086
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order                                                                      

C14F11.2 Aff_C14F11.2 P W All gene names: C14F11.2; CE29578; WBGene00015779; WP:CE29578; XG828
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster A, Reinke et al 2004, list of genes in                                  
                                              cluster order                                                                      

C14H10.2 Aff_C14H10.2 P W All gene names: C14H10.2; CE23543; WBGene00007592; WP:CE23543; XK862
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster A, Reinke et al 2004, list of genes in cluster                             
                                              order, Reinke et al 2004, herm soma enriched genes,                                
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated, Wang et                             
                                              al 2003  S4 Climbing, Wang et al 2003  S3  genes pass                              
                                              one-way ANOVA, Wang et al 2003  S4 genes pass                                      
                                              two-wayANOVA P0                                                                    

C16A3.4 Aff_C16A3.4 P W All gene names: C16A3.4; 3H473; CE04004; WBGene00015809; WP:CE04004
                                              
Member of lists (Publications lists):
                                              Kwon et al 2004 T1 late-induction                                 
                                              Ethanol-response, McCarroll et al 2004  SFig5 conserved                            
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, intrinsic, Reinke et al                                
                                              2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt                            
                                              herm vs wt male enriched gen, Reinke et al 2004, GO                                
                                              categories, ViswanathanM et al 2005  S2 sir-2.1                                    
                                              regulated                                                                          

C23F12.1 Aff_B0272.5 P W All gene names: C23F12.1; CE32133; CE32134; WBGene00016006; WP:CE32133; WP:CE32134; XK45
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order, Reinke et al 2004, list of genes in                                 
                                              cluster B                                                                          

C25D7.6 Aff_C25D7.6 P W All gene names: mcm-3; C25D7.6; 5P538; CE08392; NM_074305; WBGene00003155; WP:CE08392 WormBase description: mcm-3 encodes a member of the MCM2/3/5 family with similarity to human DNA replication licensing factor, MCM3, and affects embryonic viability. WormBase CDS description: DNA replication licensing factor MCM3
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, ViswanathanM et al 2005  S2 sir-2.1 regulated                             

C25G6.2 Aff_C25G6.2 P W All gene names: tsp-9; C25G6.2; CE04083; NM_075831; WBGene00006635; WP:CE04083; XB865 WormBase description: transpanin
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated, Wang et al 2003  S4 Early genes, Wang et al                             
                                              2003  S3  genes pass one-way ANOVA, Wang et al 2003  S4                            
                                              genes pass two-wayANOVA P0                                                         

C26D10.2 Aff_C26D10.2 P W All gene names: hel-1; C26D10.2; C26D10.2b.1; C26D10.2b.2; 2I618; CE03025; CE32593; WBGene00001840; WP:CE03025; WP:CE32593; hel WormBase description: translation initiation factor eIF-4A
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke                            
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, oogenesis enriched genes, Reinke et al 2004, wt                              
                                              herm vs wt male enriched gen, ViswanathanM et al 2005                              
                                              S2 sir-2.1 regulated                                                               

C31C9.2 Aff_C31C9.2 P W All gene names: C31C9.2; C31C9.2.1; C31C9.2.2; 2N928; CE08497; WBGene00007836; WP:CE08497 WormBase description: C31C9.2 is orthologous to the human gene PHOSPHOGLYCERATE DEHYDROGENASE (PHGDH; OMIM:606879), which when mutated leads to phosphoglycerate dehydrogenase deficiency. WormBase CDS description: D-3-Phosphoglycerate dehydrogenase
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Non dauer genes                                 
                                              P<0.05, McCarroll et al 2004  SFig5 conserved w/ yeast,                            
                                              McCarroll et al 2004  SFig1-4 conserved w/ Drosoph,                                
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated, Wang et                             
                                              al 2003  S3  genes pass one-way ANOVA, Wang et al 2003                             
                                              S4 Dauer Enriched, Wang et al 2003  S4 genes pass                                  
                                              two-wayANOVA P0                                                                    

C31G12.1 Aff_C31G12.1 P W All gene names: C31G12.1; 5S657; CE15660; WBGene00007850; WP:CE15660
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes, ViswanathanM et                            
                                              al 2005  S2 sir-2.1 regulated                                                      

C31H5.4 Aff_C31H5.4 P W All gene names: C31H5.4; C31H5.4.1; C31H5.4.2; 1J618; CE17484; NM_060029; WBGene00007855; WP:CE17484
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated, Wang et al 2003  S3  genes pass one-way                                 
                                              ANOVA, Wang et al 2003  S4 Dauer Enriched, Wang et al                              
                                              2003  S4 genes pass two-wayANOVA P0                                                

C34D4.12 Aff_C34D4.12 P W All gene names: cyn-12; cyp-12; C34D4.12; 4H894; CE17506; NM_068717; WBGene00000888; WP:CE17506 WormBase description: cyp-12 encodes a member of the cyclophilin family.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt herm vs wt male enriched gen, Reinke et al                             
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated                                                         

C35C5.4 Aff_C35C5.4 P W All gene names: mig-2; C35C5.4; CE18544; NM_077530; WBGene00003239; WP:CE18544; XM167 WormBase description: mig-2 encodes a member of the Rho family of GTP-binding proteins that affects the migration of Q neuroblasts, HSN cells, and CAN cells as well as axon outgrowth and guidance; it is expressed in early embryos and expressed in adults in the vulva, distal tip cells of the gonad, and the sex myoblasts and their descendants. WormBase CDS description: RAS-related protein
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, ViswanathanM et al 2005  S2                                  
                                              sir-2.1 regulated                                                                  

C35E7.5 Aff_C35E7.5 P W All gene names: C35E7.5; 1L403; CE17518; CE32817; WBGene00016457; WP:CE17518; WP:CE32817
                                              
Member of lists (Publications lists):
                                              Murphy et al 2003  Fig2 Class2 shorten                            
                                              lifespan, Reinke et al 2004, list of genes in cluster                              
                                              order, Reinke et al 2004, wt herm vs wt male enriched                              
                                              gen, Reinke et al 2004, list of genes in cluster E,                                
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated,                                     
                                              ViswanathanM et al 2005  S2 daf-16 Resveratrol                                     

C36E8.3 Aff_C36E8.3 P W All gene names: C36E8.3; 3F99; CE30889; WBGene00007982; WP:CE30889
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, ViswanathanM et al 2005  S2                                  
                                              daf-16 Resveratrol                                                                 

C39E6.4 Aff_C39E6.3 P W All gene names: mls-2; C39E6.4; CE30891; NM_076414; WBGene00003377; WP:CE30891; XF378
C44C1.1 Aff_C44C1.1 P W All gene names: C44C1.1; CE35432; WBGene00016641; WP:CE35432; XB601
                                              
Member of lists (Publications lists):
                                              Romagnolo et al 2002  Fig3b Unkown,                               
                                              Wang et al 2003  S4 Early genes, Wang et al 2003  S3                               
                                              genes pass one-way ANOVA, Wang et al 2003  S4 genes                                
                                              pass two-wayANOVA P0                                                               

C44H4.2 Aff_C44H4.2 P W All gene names: sym-5; C44H4.2; CE08723; NM_078024; WBGene00006370; WP:CE08723; XP197 WormBase description: sym-5 encodes a predicted transmembrane protein that contains 13 contiguous leucine-rich repeats (LRRs) and that is similar to SYM-1, a secreted protein involved in muscle attachment; sym-5 activity appears to be required for embryogenesis and functionally overlaps with that of sym-1 and mec-8 in affecting muscle attachment; in addition, loss of sym-5 activity via RNA-mediated interference (RNAi) in a hypersensitized strain indicates that SYM-5 may also be required for locomotion, body morphology, and normal rates of postembryonic growth. WormBase CDS description: Drosophila chaoptin protein like
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order, Reinke et al 2004, list of genes in                                 
                                              cluster B, ViswanathanM et al 2005  S2 daf-16                                      
                                              Resveratrol, Wang et al 2003  S3  genes pass one-way                               
                                              ANOVA, Wang et al 2003  S4 LateList, Wang et al 2003                               
                                              S4 genes pass two-wayANOVA P0                                                      

C47D12.1 Aff_C47D12.1 P W All gene names: trr-1; C47D12.1; C47D12.1b.1; C47D12.1b.2; 2L952; CE36692; CE36693; CE38054; WBGene00007028; WP:CE36692; WP:CE36693; WP:CE38054 WormBase description: Yeast YHP9 like
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, ViswanathanM et al 2005  S2 sir-2.1 regulated,                            
                                              ViswanathanM et al 2005  S2 daf-16 Resveratrol                                     

C52D10.6 Aff_C52D10.6 P W All gene names: skr-12; C52D10.6; 4S111; CE17590; NM_070644; WBGene00004818; WP:CE17590 WormBase description: skr-12 encodes a homolog of Skp1 in S. cerevisiae, a core component of the SCF (Skp1p, Cullin, F-box) ubiquitin-ligase complex that facilitates ubiquitin-mediated protein degradation; SKR-12 has no known function in vivo, since skr-12(RNAi) animals are at least superficially normal. WormBase CDS description: cyclin A-associated protein
                                              
Member of lists (Publications lists):
                                              Lund et al 2002  Fig3D Oocyte-en,                                 
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated,                                     
                                              ViswanathanM et al 2005  S2 daf-16 Resveratrol                                     

C52D10.7 Aff_C52D10.7 P W All gene names: skr-9; C52D10.7; 4S107; CE17591; NM_070642; WBGene00004815; WP:CE17591 WormBase description: skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation. WormBase CDS description: cyclin A-associated protein
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Non dauer genes                                 
                                              P<0.05, Murphy et al 2003  Fig2 Class2 shorten                                     
                                              lifespan, Reinke et al 2004, list of genes in cluster                              
                                              order, Reinke et al 2004, intrinsic, Reinke et al 2004,                            
                                              wt vs glp-4 enriched genes, Reinke et al 2004, wt herm                             
                                              vs wt male enriched gen, Reinke et al 2004, list of                                
                                              genes in cluster E, ViswanathanM et al 2005  S2 sir-2.1                            
                                              regulated                                                                          

C52D10.9 Aff_C52D10.9 P W All gene names: skr-8; C52D10.9; C52D10.9.1; C52D10.9.2; 4S108; CE17593; NM_070643; WBGene00004814; WP:CE17593 WormBase description: skr-8 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-8 is required for is required for posterior body morphogenesis, embryonic and larval development, and cell proliferation; SKR-8 can interact with CUL-1, a C. elegans cullin homolog. WormBase CDS description: cyclin A-associated protein
                                              
Member of lists (Publications lists):
                                              Kwon et al 2004  T1 late-repression                               
                                              Ethanol-respon, Lund et al 2002  Fig3D Oocyte-en,                                  
                                              Murphy et al 2003  Fig2 Class2 shorten lifespan, Reinke                            
                                              et al 2004, fem1 enriched genes, Reinke et al 2004,                                
                                              list of genes in cluster order, Reinke et al 2004,                                 
                                              oogenesis enriched genes, Reinke et al 2004, wt vs                                 
                                              glp-4 enriched genes, Reinke et al 2004, wt herm vs wt                             
                                              male enriched gen, Reinke et al 2004, list of genes in                             
                                              cluster E, ViswanathanM et al 2005  S2 sir-2.1                                     
                                              regulated                                                                          

C55A6.5 Aff_C55A6.5 P W All gene names: sdz-8; C55A6.5; 5L996; CE09002; WBGene00008334; WP:CE09002 WormBase description: alcohol dehydrogenase
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 daf-16                                
                                              Resveratrol                                                                        

C56C10.3 Aff_C56C10.3 P W All gene names: phi-27; tag-309; C56C10.3; C56C10.3.1; C56C10.3.2; 2G881; CE02568; WBGene00016961; WP:CE02568
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, ViswanathanM et al 2005  S2 sir-2.1 regulated                             

D1009.2 Aff_D1009.2 P W All gene names: cyn-8; cyp-8; D1009.2; CE04286; CE27892; NM_077105; WBGene00000884; WP:CE04286; WP:CE27892; XJ531 WormBase description: cyp-8 encodes a peptidyl-propyl cis-trans isomerase of the cyclophilin family; cyclophilins are implicated in protein folding, however the precise role of cyp-8 is not known; a CYP-8-fusion protein localises specifically to gut cell nuclei.
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

D1081.8 Aff_D1081.8 P W All gene names: phi-7; D1081.8; D1081.8.1; D1081.8.2; 1J71; CE05540; WBGene00008386; WP:CE05540 WormBase description: MYB transforming protein
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke                            
                                              et al 2004, list of genes in cluster order, Reinke et                              
                                              al 2004, oogenesis enriched genes, Reinke et al 2004,                              
                                              wt vs glp-4 enriched genes, Reinke et al 2004, wt herm                             
                                              vs wt male enriched gen, Reinke et al 2004, GO                                     
                                              categories, Reinke et al 2004, list of genes in cluster                            
                                              E                                                                                  

E01G4.5 Aff_E01G4.5 P W All gene names: E01G4.5; 2N763; CE23623; WBGene00008447; WP:CE23623
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Dauer specific genes                            
                                              P<0.05, Reinke et al 2004, fem1 enriched genes, Reinke                             
                                              et al 2004, list of genes in cluster order, Reinke et                              
                                              al 2004, mixed oogenesis soma, Reinke et al 2004, IVb                              
                                              male soma enriched genes, Reinke et al 2004, GO                                    
                                              categories, ViswanathanM et al 2005  S2 daf-16                                     
                                              Resveratrol, ViswanathanM et al 2005  S2 sir-2.1                                   
                                              regulated, Wang et al 2003  S8 SAGE genes in the dauer                             
                                              exit, Wang et al 2003  S7 SAGE genes in the dataset                                

E02D9.1 Aff_C37A2.1 P W All gene names: C37A2.1; E02D9.1; E02D9.1b.1; E02D9.1b.2; 1H379; CE08610; CE27902; CE31335; CE31336; WBGene00017098; WP:CE08610; WP:CE27902; WP:CE31335; WP:CE31336 WormBase description: protein kinase
                                              
Member of lists (Publications lists):
                                              Lund et al 2002  Fig3D Oocyte-en,                                 
                                              McCarroll et al 2004  SFig1-4 conserved w/ Drosoph,                                
                                              Murphy et al 2003  Fig2 Class2 shorten lifespan, Reinke                            
                                              et al 2004, fem1 enriched genes, Reinke et al 2004,                                
                                              oogenesis enriched genes, Reinke et al 2004, wt vs                                 
                                              glp-4 enriched genes, Reinke et al 2004, wt herm vs wt                             
                                              male enriched gen, ViswanathanM et al 2005  S2 sir-2.1                             
                                              regulated, Wang et al 2003  S5 genes common to feeding                             
                                              ANOVA, Wang et al 2003  S3  genes pass one-way ANOVA,                              
                                              Wang et al 2003  S4 Early genes, Wang et al 2003  S4                               
                                              genes pass two-wayANOVA P0                                                         

EEED8.7 Aff_EEED8.7 P W All gene names: rsp-4; srp-2; EEED8.7; 2F678; CE01891; CE27910; CeSC35; NM_062612; NM_062613; WBGene00004701; WP:CE01891; WP:CE27910 WormBase description: splicing factor SC35
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, intrinsic,                                
                                              Reinke et al 2004, wt vs glp-4 enriched genes,                                     
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

F08C6.4 Aff_F08C6.4 P W All gene names: sto-1; F08C6.4; CE27924; NM_076880; WBGene00006063; WP:CE27924; XI183 WormBase description: Erythrocyte band 7 integral membrane protein (human)
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster A, Reinke et al 2004, list of genes in cluster                             
                                              order                                                                              

F08F1.8 Aff_F08F1.8 P W All gene names: tth-1; F08F1.8; F08F1.8.1; F08F1.8.2; CE27929; NM_077029; WBGene00006649; WP:CE27929; XJ42 WormBase description: tth-1 encodes a thymosin beta ortholog that contains four functionally distinct thymosin beta repeats; in vitro, TTH-1 binds multiple actin monomers as well as filamentous actin suggesting that, as its homology predicts, TTH-1 plays a direct role in regulating actin polymerization and cytoskeletal organization in C. elegans; consistent with this, loss of tth-1 activity via a deletion mutation that removes upstream sequences results in animals with a dumpy morphology that are sterile as a result of maternal effect lethality associated with deformed oocytes containing abnormally distributed actin; tth-1 mRNA is present throughout development, while TTH-1 protein is detected in the adult gonad in the inside edges of the membranous structures surrounding germline nuclei, the cytoplasm and cortex of oocytes, early embryos at points of cell contact, the developing nerve ring, and then throughout the larval and adult body, with specific enrichment in the intestine and spermatheca.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, ViswanathanM et al 2005  S2                                  
                                              sir-2.1 regulated, ViswanathanM et al 2005  S2 daf-16                              
                                              Resveratrol                                                                        

F10E7.11 Aff_F10E7.11 P W All gene names: F10E7.11; 2H410; CE32367; WBGene00017352; WP:CE32367
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster F, Reinke et al 2004, fem1 enriched genes,                                 
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt vs glp-4 enriched genes, Reinke et al 2004,                            
                                              wt herm vs wt male enriched gen, Reinke et al 2004, GO                             
                                              categories, ViswanathanM et al 2005  S2 daf-16                                     
                                              Resveratrol, ViswanathanM et al 2005  S2 sir-2.1                                   
                                              regulated                                                                          

F13E6.1 Aff_F13E6.1 P W All gene names: F13E6.1; CE31474; WBGene00008745; WP:CE31474; XL294 WormBase description: D52 protein
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster A, Reinke et al 2004, list of genes in cluster                             
                                              order, ViswanathanM et al 2005  S2 sir-2.1 regulated                               

F15B10.3 Aff_F15B10.3 P W All gene names: F15B10.3; 4H369; CE16989; WBGene00017481; WP:CE16989
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated, ViswanathanM et al 2005  S2 daf-16                                      
                                              Resveratrol                                                                        

F18E2.3 Aff_F18E2.3 P W All gene names: scc-3; F18E2.3; 5N247; CE05664; NM_073792; WBGene00004738; WP:CE05664 WormBase description: scc-3 encodes a cohesin complex subunit homologous to Saccharomyces cerevisiae Irr1p/Scc3p; SCC-3 is required during meiosis for synaptonemal complex formation and sister chromatid cohesion, proper localization of REC-8 to chromosomes, mitotic chromosome segregation, embryonic development, and vulval morphogenesis; in embryos, SCC-3 forms a cohesin complex with SCC-1, SMC-1, SMC-3, and TIM-1, a HEAT/Armadillo repeat-containing protein related to Drosophila TIMELESS; in the germline, SCC-3 associates with chromatin of transistion zone nuclei, assembles along the longitudinal axes of synapsed chromosomes at pachytene, and unlike other cohesins, localizes throughout chromatin at diakinesis; SCC-3 localization requires TIM-1, and SCC-3 and REC-8 are mutually required for chromatin localization.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, intrinsic,                                
                                              Reinke et al 2004, list of genes in cluster F, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, wt herm vs wt male enriched gen, ViswanathanM et                             
                                              al 2005  S2 sir-2.1 regulated                                                      

F20D1.3 Aff_F20D1.3 P W All gene names: F20D1.3; F20D1.3.1; F20D1.3.2; CE31486; WBGene00008975; WP:CE31486; XP595
F22B5.7 Aff_F22B5.8 P W All gene names: zyg-9; F22B5.7; F22B5.8; 2I753; CE20707; NM_063383; WBGene00006994; WP:CE20707 WormBase description: zyg-9 encodes a predicted microtubule-association protein (MAP) of the XMAP215 family; during early embryonic development, maternal zyg-9 activity is required for microtubule-dependent processes such as meiotic and mitotic spindle organization and pronuclear migration; further, zyg-9 is essential for formation of long astral microtubules; ZYG-9 is required for centrosomal localization of TAC-1, the sole C. elegans TACC family member, with which it interacts, and mutually stabilizes, in vivo; in early embryos, ZYG-9 localizes to the meiotic spindle and spindle poles, as well as to mitotic centrosomes; during metaphase and anaphase ZYG-9 localizes to the central spindle region, and during interphase ZYG-9 is cytoplasmic; proper localization of ZYG-9 to the meiotic spindle is dependent upon wild-type activity of MEI-1, an ATPase essential for meiotic spindle formation, while proper localization of ZYG-9 to centrosomes is dependent, at least in part, upon TAC-1. WormBase CDS description: elongation factor
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, intrinsic, Reinke et al                                
                                              2004, list of genes in cluster F, Reinke et al 2004, wt                            
                                              vs glp-4 enriched genes, Reinke et al 2004, list of                                
                                              genes in cluster order                                                             

F22F1.1 Aff_F22F1.1 P W All gene names: hil-3; F22F1.1; H1.3; CE04443; NM_076974; WBGene00001854; WP:CE04443; XI779 WormBase description: histone h1
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster A, Reinke et al 2004, list of genes in cluster                             
                                              order, Reinke et al 2004, GO categories, Reinke et al                              
                                              2004, IVb male soma enriched genes                                                 

F22F4.2 Aff_F22F4.2 P W All gene names: inx-3; opu-3; F22F4.2; F22F4.2.1; F22F4.2.2; CE33055; NM_076601; WBGene00002125; WP:CE33055; XG615 WormBase description: unc-7-like protein
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, wt herm vs wt male enriched gen, Reinke et al                                
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated, ViswanathanM et al 2005  S2                            
                                              daf-16 Resveratrol                                                                 

F23B12.8 Aff_F23B12.8 P W All gene names: bmk-1; klp-14; F23B12.8; F23B12.8.1; F23B12.8.2; 5O934; CE09600; NM_074181; WBGene00000257; WP:CE09600 WormBase description: a homolog of BimC kinesin; affects embryogenesis, spindle and chromosome positioning during early embryogenesis, and genetically interacts with air-2. WormBase CDS description: kinesin-like protein
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, intrinsic, Reinke et al                                
                                              2004, Fig2b shared gemlines, Reinke et al 2004, wt vs                              
                                              glp-4 enriched genes, Reinke et al 2004, wt males vs                               
                                              glp4 male enriched , ViswanathanM et al 2005  S2                                   
                                              sir-2.1 regulated                                                                  

F23B2.6 Aff_F23B2.6 P W All gene names: aly-2; ref-2; F23B2.6; 4J913; CE09586; NM_069193; WBGene00000121; WP:CE09586 WormBase description: vimentin like
                                              
Member of lists (Publications lists):
                                              Kwon et al 2004 T1 late-induction                                 
                                              Ethanol-response, Reinke et al 2004, list of genes in                              
                                              cluster F, Reinke et al 2004, fem1 enriched genes,                                 
                                              Reinke et al 2004, Fig2b shared gemlines, Reinke et al                             
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, oogenesis enriched genes, Reinke et al 2004, wt                              
                                              vs glp-4 enriched genes, Reinke et al 2004, wt males vs                            
                                              glp4 male enriched , Reinke et al 2004, wt herm vs wt                              
                                              male enriched gen, ViswanathanM et al 2005  S2 sir-2.1                             
                                              regulated                                                                          

F23F12.9 Aff_F23F12.9 P W All gene names: F23F12.9; 3H569; CE01256; CE32389; WBGene00017755; WP:CE01256; WP:CE32389
                                              
Member of lists (Publications lists):
                                              Portman et al 2004  T1 25 candidate                               
                                              ray genes, Reinke et al 2004, list of genes in cluster                             
                                              A, Reinke et al 2004, list of genes in cluster order                               

F23H11.1 Aff_F23H11.1 P W All gene names: bra-2; tag-285; F23H11.1; 3B529; CE09609; NM_064891; WBGene00017757; WP:CE09609 WormBase description: The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Non dauer genes                                 
                                              P<0.05, Reinke et al 2004, fem1 enriched genes, Reinke                             
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, oogenesis enriched genes, Reinke et al 2004, wt                              
                                              herm vs wt male enriched gen, Reinke et al 2004, list                              
                                              of genes in cluster E, ViswanathanM et al 2005  S2                                 
                                              sir-2.1 regulated                                                                  

F25B5.4 Aff_F25B5.4 P W All gene names: ubq-1; F25B5.4; F25B5.4a.1; F25B5.4a.2; F25B5.4a.3; F25B5.4a.4; F25B5.4c.1; F25B5.4c.2; 3H33; CE01921; CE31915; NM_171139; NM_171868; WBGene00006727; WP:CE01921; WP:CE31915
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, ViswanathanM et al 2005  S2 sir-2.1 regulated                             

F26D10.12 Aff_F26D10.12 P W All gene names: F26D10.12; 4S221; CE19812; WBGene00009156; WP:CE19812 WormBase description: Lectin C-type domain
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order, Reinke et al 2004, list of genes in                                 
                                              cluster E                                                                          

F26E4.8 Aff_F26E4.8 P W All gene names: tba-1; F26E4.8; F26E4.8.1; F26E4.8.2; 1K362; CE09692; NM_060199; TUBA3; WBGene00006528; WP:CE09692 WormBase description: TBA-2 tubulin alpha-2 chain
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, IVb male soma enriched genes                                              

F26G5.9 Aff_F26G5.9 P W All gene names: tam-1; F26G5.9; 5F438; CE09704; NM_071934; WBGene00006523; WP:CE09704 WormBase description: tam-1 encodes a broadly expressed nuclear protein with RING finger, B-box, and glutamine/asparagine-rich domains that promotes signalling in the class B synthetic-multivulva gene pathway (which includes the lin-35/RB gene), and also promotes the activity of genes in multicopy transgenic arrays; the normal role of TAM-1's class B activity is presumably to inhibit RAS pathway activity in vulval development, while TAM-1's effect on transgenes may be through changes in the acetylation state of histones in chromatin.
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster F, Reinke et al 2004, fem1 enriched genes,                                 
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, mixed oogenesis soma                                            

F26H11.2 Aff_F26H11.2 P W All gene names: nurf-1; F26H11.2; F26H11.2a.1; F26H11.2a.2; 2O693; CE15909; CE15910; CE35294; CE35295; CE35296; CE36931; CE37638; WBGene00009180; WP:CE15909; WP:CE15910; WP:CE35294; WP:CE35295; WP:CE35296; WP:CE36931; WP:CE37638 WormBase description: Bromodomain
                                              
Member of lists (Publications lists):
                                              Kwon et al 2004 T1 transient-induction                            
                                              Ethanol-res, McCarroll et al 2004  SFig1-4 conserved w/                            
                                              Drosoph, Reinke et al 2004, IVb male soma enriched                                 
                                              genes                                                                              

F27E11.3 Aff_F27E11.3 P W All gene names: cfz-2; F27E11.3; 5D920; CE39149; CE39150; CFZ2; NM_071563; NM_071564; WBGene00000478; WP:CE39149; WP:CE39150 WormBase description: cfz-2 encodes a member of the Frizzled family of membrane receptors.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, mixed oogenesis soma,                                    
                                              ViswanathanM et al 2005  S2 daf-16 Resveratrol                                     

F28F8.3 Aff_F28F8.3 P W All gene names: lsm-5; F28F8.3; F28F8.3.1; F28F8.3.2; 5Q49; CE09757; NM_074469; WBGene00003079; WP:CE09757 WormBase description: small nuclear ribonucleoprotein E (SNRNP-E) like
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke                            
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, oogenesis enriched genes, Reinke et al 2004, GO                              
                                              categories, ViswanathanM et al 2005  S2 sir-2.1                                    
                                              regulated                                                                          

F29B9.2 Aff_F29B9.2 P W All gene names: F29B9.2; 4F429; CE09781; CE27145; WBGene00017920; WP:CE09781; WP:CE27145
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes, ViswanathanM et                            
                                              al 2005  S2 sir-2.1 regulated                                                      

F29C4.7 Aff_F29C4.7 P W All gene names: F29C4.7; F29C4.7a.1; F29C4.7a.2; F29C4.7b.1; F29C4.7b.2; 4A876; CE17724; CE31493; CE37226; WBGene00017929; WP:CE17724; WP:CE31493; WP:CE37226 WormBase description: F29C4.7 is orthologous to human RBM15 (OMIM:606077, mutated in infantile acute megakaryoblastic leukemia) and Drosophila NITO; F29C4.7 encodes a paralog of DIN-1; like DIN-1, it has N-terminal RNA recognition motifs (RRMs) and a C-terminal SID/RD (SMRT interaction domain/repressor) domain.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, mixed oogenesis soma, Reinke                             
                                              et al 2004, GO categories, ViswanathanM et al 2005  S2                             
                                              sir-2.1 regulated                                                                  

F29D11.2 Aff_F29D11.2 P W All gene names: F29D11.2; 1I212; CE09790; WBGene00009254; WP:CE09790
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, list of genes in cluster F, Reinke et al                               
                                              2004, wt vs glp-4 enriched genes, Reinke et al 2004,                               
                                              list of genes in cluster order, Reinke et al 2004, wt                              
                                              herm vs wt male enriched gen, ViswanathanM et al 2005                              
                                              S2 sir-2.1 regulated                                                               

F31D4.3 Aff_F31D4.3 P W All gene names: fkb-6; F31D4.3; F31D4.3.1; F31D4.3.2; 5V317; CE15929; NM_075625; WBGene00001431; WP:CE15929 WormBase description: FKBP-type peptidyl-prolyl cis-trans isomerases
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, intrinsic,                                
                                              Reinke et al 2004, wt vs glp-4 enriched genes,                                     
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

F32D1.10 Aff_F32D1.10 P W All gene names: mcm-7; F32D1.10; F32D1.10.1; F32D1.10.2; 5E827; CE09874; NM_071798; WBGene00003159; WP:CE09874 WormBase description: cell division control protein
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, list of genes in cluster F,                            
                                              Reinke et al 2004, fem1 enriched genes, Reinke et al                               
                                              2004, Fig2b shared gemlines, Reinke et al 2004, list of                            
                                              genes in cluster order, Reinke et al 2004, oogenesis                               
                                              enriched genes, Reinke et al 2004, wt vs glp-4 enriched                            
                                              genes, Reinke et al 2004, wt males vs glp4 male                                    
                                              enriched , Reinke et al 2004, wt herm vs wt male                                   
                                              enriched gen, ViswanathanM et al 2005  S2 sir-2.1                                  
                                              regulated                                                                          

F33E2.5 Aff_F33E2.5 P W All gene names: F33E2.5; F33E2.5.1; F33E2.5.2; 1N184; CE09906; NM_060790; WBGene00009361; WP:CE09906
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Non dauer genes                                 
                                              P<0.05                                                                             

F33H2.3 Aff_F33H2.3 P W All gene names: F33H2.3; F33H2.3.1; F33H2.3.2; 1P627; CE17766; WBGene00009367; WP:CE17766 WormBase description: Leucine Rich Repeat (2 copies) (2 domains)
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, oogenesis enriched genes,                                       
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated, Wang et                             
                                              al 2003  S5 genes common to feeding ANOVA, Wang et al                              
                                              2003  S3  genes pass one-way ANOVA                                                 

F35G12.9 Aff_F35G12.9 P W All gene names: apc-11; F35G12.9; 3F684; CE00978; NM_065536; WBGene00000145; WP:CE00978 WormBase description: apc-11 encodes a predicted key catalytic subunit of the anaphase promoting complex that is required for embryonic development past the embryonic one- cell stage. WormBase CDS description: Zinc finger, C3HC4 type (RING finger)
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, list of genes in cluster                               
                                              order, Reinke et al 2004, herm soma enriched genes,                                
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

F36A4.7 Aff_F36A4.7 P W All gene names: ama-1; F36A4.7; 4F21; CE28300; NM_068122; WBGene00000123; WP:CE28300 WormBase description: ama-1 encodes the large subunit of RNA polymerase II required for mRNA transcription; AMA-1 is essential for proper embryonic development, particularly for the early division and migration of the endodermal precursor (E) cells that initiate gastrulation; AMA-1 is expressed ubiquitously in the developing embryo until the 550-cell stage. WormBase CDS description: RNA polymerase II
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, intrinsic, Reinke et al                                
                                              2004, wt vs glp-4 enriched genes                                                   

F37A4.8 Aff_F37A4.8 P W All gene names: isw-1; F37A4.8; 3H794; CE29792; NM_066067; WBGene00002169; WP:CE29792 WormBase description: isw-1 encodes a homolog of the chromatin remodeling ATPase ISW1 that may act downstream of or in parallel to synMuv genes, and upstream of or in parallel to the RTK Ras pathway.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, list of genes in cluster                               
                                              order, Reinke et al 2004, list of genes in cluster E,                              
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

F39G3.3 Aff_F39G3.3 P W All gene names: F39G3.3; 5F211; CE33083; WBGene00018208; WP:CE33083
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

F41G3.15 Aff_F41G3.12 P W All gene names: F41G3.15; CE39018; WBGene00018306; WP:CE39018
F44A6.2 Aff_F44A6.2 P W All gene names: nhr-24; sex-1; F44A6.2; F44A6.2.1; F44A6.2.2; CE03323; NM_077312; WBGene00004786; WP:CE03323; XK820; cnr14 WormBase description: sex-1 encodes a DNA-binding protein that is a member of the nuclear hormone receptor superfamily of transcriptional regulators; during embryonic development, SEX-1 functions as an X chromosome signal element that transmits the primary sex-determination signal by negatively regulating transcription of xol-1, a gene whose expression levels correlate with hermaphrodite or male development (low xol-1 levels result in hermaphrodite development, high xol-1, in that of males); in vivo, SEX-1 can associate with extrachromosomal arrays containing the xol-1 promoter, indicating that SEX-1's affect on xol-1 transcription is likely to be direct; SEX-1 localizes to nuclei from oogenesis through mid-embryogenesis, with highest levels of expression visible during early gastrulation (28-100-cell-stage); the SEX-1 expression pattern appears to be similar in hermaphrodites and males. WormBase CDS description: nuclear hormone receptor
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

F44G4.4 Aff_F44G4.4 P W All gene names: tag-169; F44G4.4; 2J289; CE02231; CE36440; WBGene00006514; WP:CE02231; WP:CE36440 WormBase description: RNA binding protein
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster F, Reinke et al 2004, fem1 enriched genes,                              
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt vs glp-4 enriched genes, Reinke et al 2004,                            
                                              wt herm vs wt male enriched gen, Reinke et al 2004, GO                             
                                              categories, ViswanathanM et al 2005  S2 daf-16                                     
                                              Resveratrol, ViswanathanM et al 2005  S2 sir-2.1                                   
                                              regulated                                                                          

F45E1.6 Aff_F45E1.6 P W All gene names: his-71; F45E1.6; F45E1.6.1; F45E1.6.2; CE01943; NM_076943; WBGene00001945; WP:CE01943; XI600 WormBase description: his-71 encodes an H3 histone required for embryonic viability, body morphology, and larval viability. WormBase CDS description: Histone H3
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, ViswanathanM et al 2005  S2 sir-2.1 regulated                             

F45E4.2 Aff_F45E4.2 P W All gene names: plp-1; F45E4.2; F45E4.2.1; F45E4.2.2; 4I399; CE10494; NM_068840; WBGene00004046; WP:CE10494 WormBase description: plp-1 encodes a protein containing three PUR repeats that are predicted to bind DNA/RNA and has similarity to the mammalian transcription factor pur alpha, and is required for embryonic development, development of the pharynx, and affects formation of the intestine; interacts with an Lef-1 site within the end-1 promoter and binding is regulated by phosphorylation
                                              
Member of lists (Publications lists):
                                              Baugh et al 2005, PAL-1 target genes,                             
                                              Kwon et al 2004 T1 late-induction Ethanol-response,                                
                                              McCarroll et al 2004  SFig1-4 conserved w/ Drosoph,                                
                                              Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs                             
                                              glp-4 enriched genes, Reinke et al 2004, wt herm vs wt                             
                                              male enriched gen, Romagnolo et al 2002  Fig3b TF,                                 
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

F47D12.5 Aff_F47D12.5 P W All gene names: F47D12.5; 3H372; CE01949; WBGene00018561; WP:CE01949
                                              
Member of lists (Publications lists):
                                              Lund et al 2002  Fig1 aging-regulated                             
                                              genes, ViswanathanM et al 2005  S2 sir-2.1 regulated,                              
                                              ViswanathanM et al 2005  S2 daf-16 Resveratrol                                     

F49E12.6 Aff_F49E12.6 P W All gene names: F49E12.6; 2I705; CE37018; WBGene00009899; WP:CE37018 WormBase description: The F49E12.6 gene encodes a protein with two E2F domains that may be involved in apoptosis. WormBase CDS description: RBB3 like protein
                                              
Member of lists (Publications lists):
                                              Jiang et al 2001  Fig3 Rb complex                                 
                                              genes, Reinke et al 2004, list of genes in cluster                                 
                                              order, Reinke et al 2004, list of genes in cluster B,                              
                                              ViswanathanM et al 2005  S2 daf-16 Resveratrol                                     

F52C12.5 Aff_F52C12.5 P W All gene names: elt-6; F52C12.5; F52C12.5.1; F52C12.5.2; 4C685; CE31536; NM_067743; WBGene00001253; WP:CE31536
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, ViswanathanM et al 2005  S2 daf-16                                       
                                              Resveratrol                                                                        

F53E10.1 Aff_F53E10.1 P W All gene names: F53E10.1; F53E10.1.1; F53E10.1.2; 5D95; CE10920; WBGene00018758; WP:CE10920
F53F4.14 Aff_F53F4.14 P W All gene names: F53F4.14; F53F4.14.1; F53F4.14.2; 5O109; CE29593; WBGene00009996; WP:CE29593
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt herm vs wt male enriched gen, Reinke et al                             
                                              2004, list of genes in cluster E                                                   

F54B11.3 Aff_F54B11.3 P W All gene names: unc-84; F54B11.3; CE27761; CE28236; WBGene00006816; WP:CE27761; WP:CE28236; XO207 WormBase description: unc-84 encodes a transmembrane protein that contains a SUN domain with homology to S. pombe Sad1 and affects nuclear migration and anchoring of various cell types together with UNC-83 and ANC-1, thereby affecting coordinated locomotion, vulval formation, and egg laying; UNC-84 is localized to the nuclear envelope and requires LMN-1 for this localization, and it is expressed in the nuclear envelope of essentially all adult and embryonic cells.
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

F54D10.1 Aff_F54D10.1 P W All gene names: skr-15; F54D10.1; 2E115; CE19451; NM_062261; WBGene00004821; WP:CE19451 WormBase description: The skr-15 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-15(RNAi) animals are at least superficially normal.
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Non dauer genes                                 
                                              P<0.05, Reinke et al 2004, intrinsic, Reinke et al                                 
                                              2004, wt vs glp-4 enriched genes, Reinke et al 2004,                               
                                              list of genes in cluster order, Reinke et al 2004, wt                              
                                              herm vs wt male enriched gen, Reinke et al 2004, list                              
                                              of genes in cluster E, ViswanathanM et al 2005  S2                                 
                                              sir-2.1 regulated                                                                  

F54D8.1 Aff_F54D8.1 P W All gene names: dpy-17; F54D8.1; F54D8.1.1; F54D8.1.2; 3G197; CE11066; NM_065685; WBGene00001076; WBGene00018799; WP:CE11066 WormBase description: Uncloned locus that affects body length and outgrowth of posterior canal cell processes.
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster A, Reinke et al 2004, list of genes in cluster                             
                                              order, Reinke et al 2004, wt herm vs wt herm enriched                              
                                              gen, Reinke et al 2004, IVb male soma enriched genes,                              
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated,                                     
                                              ViswanathanM et al 2005  S2 daf-16 Resveratrol                                     

F55C5.4 Aff_F55C5.4 P W All gene names: F55C5.4; 5M755; CE11156; WBGene00010093; WP:CE11156
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt herm vs wt male enriched gen, Reinke et al                             
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 daf-16 Resveratrol                                                        

F55C9.8 Aff_F55C9.8 P W All gene names: fbxb-62; F55C9.8; 5T772; CE18740; WBGene00010105; WP:CE18740 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 daf-16                                
                                              Resveratrol                                                                        

F56A8.6 Aff_F56A8.6 P W All gene names: cpf-2; F56A8.6; F56A8.6.1; F56A8.6.2; 3O356; CE16126; NM_067333; WBGene00000774; WP:CE16126 WormBase description: RNA recognition motif. (aka RRM, RBD, or RNP domain)
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, intrinsic, Reinke et al                                
                                              2004, wt vs glp-4 enriched genes, Reinke et al 2004, GO                            
                                              categories                                                                         

F56C9.1 Aff_F56C9.1 P W All gene names: CEGLC-7B; Ce-glc-7beta; gsp-2; F56C9.1; F56C9.1.1; F56C9.1.2; 3I433; CE01319; WBGene00001748; WP:CE01319
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke                            
                                              et al 2004, mixed oogenesis soma, Reinke et al 2004, GO                            
                                              categories, ViswanathanM et al 2005  S2 sir-2.1                                    
                                              regulated                                                                          

F56D5.1 Aff_F56D5.1 P W All gene names: col-121; F56D5.1; 4K160; CE05967; NM_069254; WBGene00000695; WP:CE05967 WormBase description: collagen
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster A, Reinke et al 2004, list of genes in cluster                             
                                              order, ViswanathanM et al 2005  S2 sir-2.1 regulated                               

F58A4.3 Aff_F58A4.3 P W All gene names: hcp-3; F58A4.3; 3K704; CE00219; NM_066727; WBGene00001831; WP:CE00219 WormBase description: The hcp-3 gene encodes a centromere protein (CENP)-A homolog required for kinetochore function; inactivation of hcp-3 in one-cell embryos by RNAi causes a complete loss of kinetochores, with total failure of chromosomes to segregate properly during mitosis, to recruit components to the kinetochore other than HCP-3, or to assemble a stable mitotic spindle; in addition, HCP-4 fails to localize properly to the kinetochore in hcp-3(RNAi) embryos. WormBase CDS description: Histone H3 similarity
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, Fig2b shared gemlines, Reinke                            
                                              et al 2004, list of genes in cluster order, Reinke et                              
                                              al 2004, oogenesis enriched genes, Reinke et al 2004,                              
                                              wt vs glp-4 enriched genes, Reinke et al 2004, wt males                            
                                              vs glp4 male enriched , Reinke et al 2004, wt herm vs                              
                                              wt male enriched gen, Reinke et al 2004, list of genes                             
                                              in cluster E, ViswanathanM et al 2005  S2 sir-2.1                                  
                                              regulated                                                                          

F58B3.9 Aff_F58B3.9 P W All gene names: F58B3.9; 4M404; CE11362; WBGene00010234; WP:CE11362 WormBase description: Transthyretin-like family
                                              
Member of lists (Publications lists):
                                              Murphy et al 2003  Fig2 Class2 shorten                            
                                              lifespan, Reinke et al 2004, list of genes in cluster                              
                                              order, Reinke et al 2004, intrinsic, Reinke et al 2004,                            
                                              wt vs glp-4 enriched genes, Reinke et al 2004, wt herm                             
                                              vs wt male enriched gen, Reinke et al 2004, GO                                     
                                              categories, Reinke et al 2004, list of genes in cluster                            
                                              E, ViswanathanM et al 2005  S2 daf-16 Resveratrol,                                 
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

F58H10.1 Aff_F58H10.1 P W All gene names: F58H10.1; 1I331; CE36173; WBGene00010291; WP:CE36173
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 daf-16                                
                                              Resveratrol, Wang et al 2003  S3  genes pass one-way                               
                                              ANOVA, Wang et al 2003  S4 Dauer Enriched, Wang et al                              
                                              2003  S4 genes pass two-wayANOVA P0                                                

H32C10.2 Aff_H32C10.B P W All gene names: H32C10.2; 4G697; CE21004; WBGene00019256; WP:CE21004
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order, Reinke et al 2004, list of genes in                                 
                                              cluster B                                                                          

K02B12.2 Aff_K02B12.2 P W All gene names: K02B12.2; 1J88; CE06063; WBGene00010495; WP:CE06063
                                              
Member of lists (Publications lists):
                                              Murphy et al 2003  Fig2 Class2 shorten                            
                                              lifespan, Reinke et al 2004, intrinsic, Reinke et al                               
                                              2004, wt vs glp-4 enriched genes, Reinke et al 2004,                               
                                              list of genes in cluster order, Reinke et al 2004, list                            
                                              of genes in cluster E, ViswanathanM et al 2005  S2                                 
                                              sir-2.1 regulated                                                                  

K02F3.4 Aff_K02F3.4 P W All gene names: zip-2; K02F3.4; K02F3.4.1; K02F3.4.2; 3B453; CE23848; WBGene00019327; WP:CE23848
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster A, Reinke et al 2004, list of genes in cluster                             
                                              order, ViswanathanM et al 2005  S2 sir-2.1 regulated,                              
                                              ViswanathanM et al 2005  S2 daf-16 Resveratrol                                     

K03B4.7 Aff_K03B4.7 P W All gene names: K03B4.7; K03B4.7a.1; K03B4.7a.2; 5F170; CE28581; CE33133; WBGene00019357; WP:CE28581; WP:CE33133
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, mixed oogenesis soma, Reinke                             
                                              et al 2004, IVb male soma enriched genes, Romagnolo et                             
                                              al 2002  Fig3b Unkown, ViswanathanM et al 2005  S2                                 
                                              sir-2.1 regulated, Wang et al 2003  S3  genes pass                                 
                                              one-way ANOVA, Wang et al 2003  S4 genes pass                                      
                                              two-wayANOVA P0, Wang et al 2003  S4 Dauer Enriched                                

K07A1.12 Aff_K07A1.12 P W All gene names: lin-53; rba-2; K07A1.12; K07A1.12.1; K07A1.12.2; 1K196; CE16234; NM_060151; WBGene00003036; WP:CE16234 WormBase description: chromatin assembly factor 1 P55 subunit like
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, list of genes in cluster F,                            
                                              Reinke et al 2004, fem1 enriched genes, Reinke et al                               
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, oogenesis enriched genes, Reinke et al 2004, wt                              
                                              vs glp-4 enriched genes, Reinke et al 2004, wt herm vs                             
                                              wt male enriched gen, ViswanathanM et al 2005  S2                                  
                                              sir-2.1 regulated                                                                  

K08A8.2 Aff_K08A8.2 P W All gene names: sox-2; K08A8.2; K08A8.2a.1; K08A8.2a.2; K08A8.2b.1; K08A8.2b.2; K08A8.2b.3; CE28595; CE31200; NM_171725; NM_171726; WBGene00004949; WP:CE28595; WP:CE31200; XI78 WormBase description: The sox-2 gene encodes a homolog of human SRY, which when mutated leads to gonadal dysgenesis (OMIM:306100).
K08E3.6 Aff_K08E3.6 P W All gene names: cyk-4; K08E3.6; 3O858; CE18872; NM_067444; WBGene00000875; WP:CE18872 WormBase description: cyk-4 encodes a GTPase activating protein (GAP) for the Rho family of GTPases that, together with ZEN-4, is sufficient to promote the formation of the large bundles of microtubules that form the central spindle during anaphase, and is required for fertility and coordinated locomotion postembryonically; localizes to the central spindle during anaphase interdependently with ZEN-4, and interacts with ZEN-4 in vitro and in vivo. WormBase CDS description: Phorbol esters/diacylglycerol binding domain (C1 domain), GTPase-activator protein for Rho-like GTPases
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, intrinsic,                                
                                              Reinke et al 2004, wt vs glp-4 enriched genes,                                     
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

K08H2.1 Aff_K08H2.1 P W All gene names: skr-21; K08H2.1; CE06159; NM_077793; WBGene00004827; WP:CE06159; XN844 WormBase description: The skr-21 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-21(RNAi) animals are at least superficially normal. WormBase CDS description: RNA polymerase II elongation factor like
K12C11.2 Aff_K12C11.2 P W All gene names: smo-1; K12C11.2; 1B815; CE18056; NM_058441; SMT3; WBGene00004888; WP:CE18056
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, ViswanathanM et al 2005  S2 sir-2.1 regulated                             

K12D12.1 Aff_K12D12.1 P W All gene names: K12D12.1; 2M169; CE06184; WBGene00010785; WP:CE06184 WormBase description: This gene encodes a protein predicted by Eisenberg and coworkers, with 52% accuracy, to be mitochondrial. WormBase CDS description: DNA topoisomerase II
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, list of genes in cluster F,                            
                                              Reinke et al 2004, fem1 enriched genes, Reinke et al                               
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, oogenesis enriched genes, Reinke et al 2004, wt                              
                                              vs glp-4 enriched genes, Reinke et al 2004, GO                                     
                                              categories                                                                         

K12H6.6 Aff_K12H6.6 P W All gene names: K12H6.6; 2D120; CE20009; CE33422; WBGene00019686; WP:CE20009; WP:CE33422
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

M04F3.1 Aff_M04F3.1 P W All gene names: M04F3.1; M04F3.1.1; M04F3.1.2; 1F339; CE12414; WBGene00019767; WP:CE12414
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes, ViswanathanM et                            
                                              al 2005  S2 sir-2.1 regulated                                                      

M110.1 Aff_M110.1 P W All gene names: col-76; M110.1; 2I497; CE35898; NM_063325; WBGene00000652; WP:CE35898 WormBase description: collagen
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order, Reinke et al 2004, list of genes in                                 
                                              cluster C, ViswanathanM et al 2005  S2 daf-16                                      
                                              Resveratrol                                                                        

M163.3 Aff_M163.3 P W All gene names: his-24; M163.3; CE12450; HH1; NM_078009; WBGene00001898; WP:CE12450; XP109 WormBase description: The his-24 gene encodes a histone H1 isoform (H1.1) that is essential for chromatin silencing and germline development. WormBase CDS description: histone H1
                                              
Member of lists (Publications lists):
                                              Murphy et al 2003  Fig2 Class2 shorten                            
                                              lifespan, Reinke et al 2004, list of genes in cluster                              
                                              A, Reinke et al 2004, list of genes in cluster order,                              
                                              Reinke et al 2004, IVb male soma enriched genes                                    

M18.7 Aff_M18.7 P W All gene names: aly-3; M18.7; M18.7.1; M18.7.2; 4M889; CE06198; NM_069900; WBGene00000122; WP:CE06198 WormBase description: RNA recognition motif. (aka RRM, RBD, or RNP domain)
                                              
Member of lists (Publications lists):
                                              Lund et al 2002   Fig3C                                           
                                              Germline-intrinsic, Reinke et al 2004, intrinsic,                                  
                                              Reinke et al 2004, wt vs glp-4 enriched genes, Reinke                              
                                              et al 2004, wt herm vs wt male enriched gen,                                       
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

M7.5 Aff_M7.5 P W All gene names: M7.5; M7.5.1; M7.5.2; 4L844; CE18887; WBGene00010882; WP:CE18887 WormBase description: Yeast YHX1 like
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke                            
                                              et al 2004, wt herm vs wt male enriched gen, Reinke et                             
                                              al 2004, mixed oogenesis soma, Reinke et al 2004, GO                               
                                              categories, ViswanathanM et al 2005  S2 sir-2.1                                    
                                              regulated                                                                          

R01H10.1 Aff_R01H10.1 P W All gene names: ccd-1; div-1; R01H10.1; 3L336; CE28840; NM_066867; WBGene00001002; WP:CE28840 WormBase description: div-1 encodes a homolog of the B subunit of the DNA polymerase alpha-primase complex; DIV-1 is required in embryos for the normal timing of interphase in cell divisions, and for the asymmetric distribution of PIE-1 and P granules. WormBase CDS description: DNA polymerase alpha associated subunit
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, ViswanathanM et al 2005  S2 sir-2.1 regulated                             

R06C7.8 Aff_R06C7.8 P W All gene names: bub-1; R06C7.8; 1H831; CE06251; NM_059650; WBGene00000275; WP:CE06251 WormBase description: bub-1 encodes a serine/threonine kinase orthologous to Saccharomyces cerevisiae BUB1 which is required for proper function of the mitotic spindle assembly checkpoint and human BUB1 (OMIM:602452) which is mutated in some colorectal cancers; BUB-1 activity is required at several stages of development, including embryogenesis; BUB-1 is expressed predominantly in the anterior of the embryo and in hypodermal seam cells during the L1 and L2 larval stages. WormBase CDS description: Eukaryotic protein kinase domain
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, intrinsic, Reinke et al                                
                                              2004, wt vs glp-4 enriched genes, Reinke et al 2004, GO                            
                                              categories, Reinke et al 2004, IVb male soma enriched                              
                                              genes, ViswanathanM et al 2005  S2 sir-2.1 regulated                               

R07B7.3 Aff_R07B7.3 P W All gene names: pqn-53; R07B7.3; 5M544; CE06265; NM_073622; WBGene00004138; WP:CE06265 WormBase description: The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, wt herm vs wt male                             
                                              enriched gen, ViswanathanM et al 2005  S2 sir-2.1                                  
                                              regulated                                                                          

R08C7.3 Aff_R08C7.3 P W All gene names: htz-1; R08C7.3; R08C7.3.1; R08C7.3.2; R08C7.3.3; 4F211; CE07426; WBGene00019947; WP:CE07426 WormBase description: histone H2A variant
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, list of genes in cluster F,                            
                                              Reinke et al 2004, fem1 enriched genes, Reinke et al                               
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, oogenesis enriched genes, Reinke et al 2004, wt                              
                                              vs glp-4 enriched genes, Reinke et al 2004, wt herm vs                             
                                              wt male enriched gen, Reinke et al 2004, GO categories,                            
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

R09B3.5 Aff_R09B3.5 P W All gene names: mag-1; R09B3.5; R09B3.5.1; R09B3.5.2; 1M504; CE16310; NM_060624; WBGene00003123; WP:CE16310 WormBase description: MAGO NASHI PROTEIN
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, ViswanathanM et al 2005  S2                                  
                                              sir-2.1 regulated                                                                  

R11.4 Aff_R11.4 P W All gene names: R11.4; CE12720; WBGene00011229; WP:CE12720; XQ824
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Non dauer genes                                 
                                              P<0.05, Reinke et al 2004, fem1 enriched genes, Reinke                             
                                              et al 2004, list of genes in cluster order, Reinke et                              
                                              al 2004, mixed oogenesis soma, Reinke et al 2004, list                             
                                              of genes in cluster E                                                              

R11H6.2 Aff_R11H6.2 P W All gene names: R11H6.2; R11H6.2.1; R11H6.2.2; 5P79; CE12772; WBGene00011250; WP:CE12772 WormBase description: Human placenta (DIFF33) protein like
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt herm vs wt male enriched gen, Reinke et al                             
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated                                                         

R12H7.3 Aff_R12H7.3 P W All gene names: skr-19; R12H7.3; CE03568; NM_077792; WBGene00004825; WP:CE03568; XN842 WormBase description: The skr-19 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-19(RNAi) animals are at least superficially normal. WormBase CDS description: RNA polymerase II elongation factor like
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

R52.1 Aff_R52.1 P W All gene names: bath-16; sdz-28; R52.1; 2C421; CE12824; WBGene00020073; WP:CE12824
                                              
Member of lists (Publications lists):
                                              Lund et al 2002  Fig3D Oocyte-en,                                 
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, list of genes in cluster E,                                     
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated,                                     
                                              ViswanathanM et al 2005  S2 daf-16 Resveratrol                                     

T03F1.6 Aff_T03F1.6 P W All gene names: T03F1.6; 1E408; CE13106; CE28248; WBGene00020188; WP:CE13106; WP:CE28248
                                              
Member of lists (Publications lists):
                                              Bishop et al 2004  T1 Upregulated in                              
                                              vhl-1 vs WT, Wang et al 2003  S4 TransientList, Wang et                            
                                              al 2003  S3  genes pass one-way ANOVA, Wang et al 2003                             
                                              S4 genes pass two-wayANOVA P0                                                      

T04A8.14 Aff_T04A8.14 P W All gene names: emb-5; T04A8.14; 3F806; CE13120; NM_065568; WBGene00001259; WP:CE13120 WormBase description: emb-5 encodes the C. elegans ortholog of the Spt6 family of RNA polymerase II transcription elongation factors; first identified in screens for temperature-sensitive embryonic lethal mutations, emb-5 is required for the correct timing of the second E (endoderm)-cell division in the early embryo and thus, for normal embryonic gastrulation; in addition, emb-5 activity is required postembryonically for proper gonad development; in yeast two-hybrid studies, EMB-5 interacts with the intracellular domains of LIN-12 and GLP-1, suggesting that EMB-5 functions as a positive downstream effector in Notch-like signaling pathways during C. elegans development; emb-5 mRNA is most abundant during embryonic stages, with lower levels apparent during the L1-L3 larval stages, and even lower levels observed during L4. WormBase CDS description: S1 RNA binding domain
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke                            
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, oogenesis enriched genes, Reinke et al 2004, wt                              
                                              herm vs wt male enriched gen, ViswanathanM et al 2005                              
                                              S2 sir-2.1 regulated                                                               

T04C10.1 Aff_T04C10.1 P W All gene names: mbk-1; T04C10.1; CE33442; NM_078059; WBGene00003149; WP:CE33442; XP440 WormBase description: mbk-1 encodes a putative dual-specificity kinase (predicted to have both serine/threonine and tyrosine substrates) that is orthologous to Drosophila MINIBRAIN and mammalian DYRK1A/MnbK and that has a glutamine/asparagine-rich domain; MBK-1 is found in most or all nuclei, is dispensable for viability, and perturbs olfaction in AWC when overexpressed. WormBase CDS description: serine/threonine kinase (2 domains)
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph                                                               

T04D3.5 Aff_T04D3.5 P W All gene names: T04D3.5; 1N922; CE13161; WBGene00011434; WP:CE13161
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, wt herm vs wt male enriched gen, Reinke et al                                
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated                                                         

T05G5.3 Aff_T05G5.3 P W All gene names: cdk-1; ncc-1; T05G5.3; T05G5.3.1; T05G5.3.2; 3K837; CE00315; WBGene00000405; WP:CE00315 WormBase description: cdk-1 encodes a cyclin-dependent kinase, orthologous to and functionally interchangeable with CDC28 from S. cerevisiae; CDK-1 is required for cell-cycle progression through M phase in both meiosis and mitosis. WormBase CDS description: serine/threonine kinase (CDC2/CDKX subfamily)
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke                            
                                              et al 2004, Fig2b shared gemlines, Reinke et al 2004,                              
                                              list of genes in cluster order, Reinke et al 2004,                                 
                                              oogenesis enriched genes, Reinke et al 2004, wt vs                                 
                                              glp-4 enriched genes, Reinke et al 2004, wt males vs                               
                                              glp4 male enriched , Reinke et al 2004, wt herm vs wt                              
                                              male enriched gen, Reinke et al 2004, list of genes in                             
                                              cluster E, ViswanathanM et al 2005  S2 sir-2.1                                     
                                              regulated                                                                          

T12G3.1 Aff_T12G3.1 P W All gene names: T12G3.1; T12G3.1.1; T12G3.1.2; 4M801; CE37554; WBGene00011737; WP:CE37554 WormBase description: Drosphila REF (2)P like
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated, Wang et al 2003  S3  genes pass one-way                                 
                                              ANOVA, Wang et al 2003  S4 Dauer Enriched, Wang et al                              
                                              2003  S4 genes pass two-wayANOVA P0                                                

T13F2.8 Aff_T13F2.8 P W All gene names: cav-1; T13F2.8; T13F2.8.1; T13F2.8.2; 4K537; CE13633; NM_069342; WBGene00000301; WP:CE13633 WormBase description: cav-1 encodes a member of the caveolin protein family that affects viability and Ras/MAP-kinase-dependent progression through the meiotic cell cycle meiotic; expressed in the adult germ line and during embryonic development. WormBase CDS description: caveolin
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Non dauer genes                                 
                                              P<0.05, Murphy et al 2003  Fig2 Class2 shorten                                     
                                              lifespan, Reinke et al 2004, intrinsic, Reinke et al                               
                                              2004, wt vs glp-4 enriched genes, Reinke et al 2004,                               
                                              list of genes in cluster order, Reinke et al 2004, list                            
                                              of genes in cluster E, ViswanathanM et al 2005  S2                                 
                                              sir-2.1 regulated                                                                  

T23B12.7 Aff_T23B12.7 P W All gene names: dnj-22; T23B12.7; 5I942; CE14038; NM_072777; WBGene00001040; WP:CE14038 WormBase description: This gene encodes a protein containing a DnaJ ('J') domain that is predicted to be mitochondrial.
                                              
Member of lists (Publications lists):
                                              Lund et al 2002   Fig3C                                           
                                              Germline-intrinsic, Reinke et al 2004, intrinsic,                                  
                                              Reinke et al 2004, wt vs glp-4 enriched genes, Reinke                              
                                              et al 2004, list of genes in cluster order, Reinke et                              
                                              al 2004, wt herm vs wt male enriched gen, Reinke et al                             
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated                                                         

T23B3.2 Aff_T23B3.2 P W All gene names: T23B3.2; 1H293; CE14010; WBGene00020710; WP:CE14010
                                              
Member of lists (Publications lists):
                                              Lund et al 2002  Fig4 Mount 15, Murphy                            
                                              et al 2003  Fig2 Class1 elongate lifespan, ViswanathanM                            
                                              et al 2005  S2 daf-16 Resveratrol                                                  

T23G5.1 Aff_T23G5.1 P W All gene names: rnr-1; T23G5.1; T23G5.1.1; T23G5.1.2; T23G5.1.3; 3K316; CE00331; NM_066638; WBGene00004391; WP:CE00331 WormBase description: Ribonucleoside-disphosphate reductase large chain
                                              
Member of lists (Publications lists):
                                              Lund et al 2002   Fig3C                                           
                                              Germline-intrinsic, McCarroll et al 2004  SFig5                                    
                                              conserved w/ yeast, McCarroll et al 2004  SFig1-4                                  
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster F, Reinke et al 2004, list of genes in                                  
                                              cluster order, ViswanathanM et al 2005  S2 sir-2.1                                 
                                              regulated, ViswanathanM et al 2005  S2 daf-16                                      
                                              Resveratrol                                                                        

T24H10.6 Aff_T24H10.6 P W All gene names: dyrb-1; T24H10.6; 2J396; CE03731; NM_063542; WBGene00012004; WP:CE03731 WormBase description: bithoraxoid-like protein
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, mixed oogenesis soma,                                    
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

T25E12.6 Aff_T25E12.6 P W All gene names: T25E12.6; 5R223; CE16467; WBGene00012021; WP:CE16467
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Non dauer genes                                 
                                              P<0.05, Murphy et al 2003  Fig2 Class2 shorten                                     
                                              lifespan, ViswanathanM et al 2005  S2 sir-2.1 regulated                            

W01A11.5 Aff_W01A11.5 P W All gene names: cpt-6; W01A11.5; 5G972; CE14398; WBGene00020911; WP:CE14398 WormBase description: carnitine palmitoyltransferase
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order, Reinke et al 2004, list of genes in                                 
                                              cluster B, ViswanathanM et al 2005  S2 sir-2.1                                     
                                              regulated, ViswanathanM et al 2005  S2 daf-16                                      
                                              Resveratrol, ViswanathanM et al 2005 S2 Resveratrol                                
                                              regulate WT                                                                        

W03F9.10 Aff_W03F9.10 P W All gene names: W03F9.10; W03F9.10.1; W03F9.10.2; 5A609; CE14540; WBGene00021004; WP:CE14540
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph                                                                            

W04A8.4 Aff_W04A8.4 P W All gene names: W04A8.4; 1O434; CE16538; WBGene00012239; WP:CE16538
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster A, Reinke et al 2004, list of genes in cluster                             
                                              order                                                                              

W08E3.1 Aff_W08E3.1 P W All gene names: snr-2; W08E3.1; W08E3.1.1; W08E3.1.2; 1N931; CE14704; NM_060947; WBGene00004915; WP:CE14704 WormBase description: small nuclear ribonucleoprotein (SNRNP)
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke                            
                                              et al 2004, oogenesis enriched genes, Reinke et al                                 
                                              2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt                            
                                              herm vs wt male enriched gen, Reinke et al 2004, GO                                
                                              categories, ViswanathanM et al 2005  S2 sir-2.1                                    
                                              regulated, Wang et al 2003  S5 genes common to feeding                             
                                              ANOVA, Wang et al 2003  S3  genes pass one-way ANOVA                               

W09C2.1 Aff_W09C2.1 P W All gene names: elt-1; W09C2.1; W09C2.1a.1; W09C2.1a.2; 4K383; CE03799; CE39113; NM_069307; WBGene00001249; WP:CE03799; WP:CE39113 WormBase description: The elt-1 gene encodes a GATA transcription factor expressed in the embryonic hypodermis, and is essential for the production of most hypodermal cells. WormBase CDS description: elongation factor ELT
                                              
Member of lists (Publications lists):
                                              Baugh et al 2005, validated PAL-1                                 
                                              target genes, Baugh et al 2005, PAL-1 target genes,                                
                                              McCarroll et al 2004  SFig5 conserved w/ yeast,                                    
                                              McCarroll et al 2004  SFig1-4 conserved w/ Drosoph,                                
                                              Reinke et al 2004, mixed sperm soma, Reinke et al 2004,                            
                                              fem3 enriched genes                                                                

Y110A2AL.4 Aff_Y110A2A_54.H P W All gene names: Y110A2AL.4; 2D131; CE33472; CE33473; WBGene00022441; WP:CE33472; WP:CE33473
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster A, Reinke et al 2004, list of genes in cluster                             
                                              order, ViswanathanM et al 2005  S2 sir-2.1 regulated,                              
                                              Wang et al 2003  S3  genes pass one-way ANOVA, Wang et                             
                                              al 2003  S4 Dauer Enriched, Wang et al 2003  S4 genes                              
                                              pass two-wayANOVA P0                                                               

Y11D7A.12 Aff_Y11D7A.12 P W All gene names: Y11D7A.12; 4K28; CE35915; WBGene00012435; WP:CE35915
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt herm vs wt male enriched gen, Reinke et al                             
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated                                                         

Y37D8A.9 Aff_Y37D8A.9 P W All gene names: CE-1; mrg-1; Y37D8A.9; Y37D8A.9.1; Y37D8A.9.2; 3N962; CE20213; NM_067274; WBGene00003406; WP:CE20213
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster F, Reinke et al 2004, fem1 enriched genes,                              
                                              Reinke et al 2004, wt vs glp-4 enriched genes, Reinke                              
                                              et al 2004, list of genes in cluster order, Reinke et                              
                                              al 2004, oogenesis enriched genes, ViswanathanM et al                              
                                              2005  S2 sir-2.1 regulated                                                         

Y38C9A.2 Aff_Y38C9A.B P W All gene names: cgp-1; Y38C9A.2; Y38C9A.2.1; Y38C9A.2.2; 5A598; CE21577; NM_070736; WBGene00000480; WP:CE21577 WormBase description: GTP-binding protein
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, mixed oogenesis soma, Reinke                             
                                              et al 2004, GO categories, ViswanathanM et al 2005  S2                             
                                              sir-2.1 regulated                                                                  

Y39G10AR.10 Aff_Y39G10A_246.A P W All gene names: Y39G10AR.10; Y39G10AR.10.1; Y39G10AR.10.2; 1C869; CE26989; WBGene00021468; WP:CE26989
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, wt herm vs wt male enriched gen, ViswanathanM et                             
                                              al 2005  S2 sir-2.1 regulated                                                      

Y39G10AR.14 Aff_Y39G10A_246.G P W All gene names: mcm-4; Y39G10AR.14; Y39G10AR.14.1; Y39G10AR.14.2; 1C888; CE21767; NM_058561; WBGene00003156; WP:CE21767 WormBase description: mcm-4 encodes a member of the MCM2/3/5 family with similarity to human MCM4 minichromosome maintenance deficient 4 protein, and affects embryonic viability, nuclear morphology in early embryos, and larval viability.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, list of genes in cluster F,                            
                                              Reinke et al 2004, fem1 enriched genes, Reinke et al                               
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, oogenesis enriched genes, Reinke et al 2004, wt                              
                                              vs glp-4 enriched genes, Reinke et al 2004, wt herm vs                             
                                              wt male enriched gen, Romagnolo et al 2002  Fig3b                                  
                                              Unkown, ViswanathanM et al 2005  S2 sir-2.1 regulated                              

Y43F8B.2 Aff_Y116F11.OO P W All gene names: Y43F8B.2; 5T994; CE21886; CE21887; WBGene00012813; WP:CE21886; WP:CE21887
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

Y46B2A.1 Aff_Y46B2_176.C P W All gene names: Y46B2A.1; 2B161; CE21951; WBGene00021576; WP:CE21951
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order, Reinke et al 2004, list of genes in                                 
                                              cluster E, ViswanathanM et al 2005  S2 daf-16                                      
                                              Resveratrol                                                                        

Y47D3B.9 Aff_Y47D3B.9 P W All gene names: Y47D3B.9; 3M554; CE19173; WBGene00012943; WP:CE19173
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 daf-16                                
                                              Resveratrol                                                                        

Y47D7A.1 Aff_Y47D7A_138.A P W All gene names: skr-7; Y47D7A.1; Y47D7A.1.1; Y47D7A.1.2; 5E901; CE22054; NM_071820; WBGene00004813; WP:CE22054 WormBase description: The skr-7 gene encodes a homolog of Skp1 in S. cerevisiae that is required for posterior body morphogenesis, embryonic and larval development, and cell proliferation.
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, intrinsic, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, wt herm vs wt male enriched gen, Reinke et al                                
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated                                                         

Y47H9C.5 Aff_Y47H9C.5 P W All gene names: dnj-27; Y47H9C.5; Y47H9C.5.1; Y47H9C.5.2; 1M477; CE20265; NM_060609; WBGene00001045; WP:CE20265 WormBase description: This gene encodes a protein containing a DnaJ ('J') domain.
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order, Reinke et al 2004, list of genes in                                 
                                              cluster C                                                                          

Y48B6A.14 Aff_Y48B6A.Q P W All gene names: hmg-1.1; Y48B6A.14; Y48B6A.14.1; Y48B6A.14.2; Y48B6A.Q; 2O541; CE29377; NM_064569; WBGene00001971; WP:CE29377 WormBase description: hmg-1.1 encodes a member of the high mobility group (HMG) family of proteins.
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

Y53F4B.9 Aff_Y53F4B.M P W All gene names: Y53F4B.9; Y53F4B.M; Y53F4B.N; 2P292; CE22399; WBGene00013156; WP:CE22399
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster F, Reinke et al 2004, list of genes in cluster                             
                                              order                                                                              

Y54E5A.4 Aff_Y105E8A.CC P W All gene names: npp-4; Y54E5A.4; Y54E5A.4.1; Y54E5A.4.2; 1P294; CE20315; NM_061151; WBGene00003790; WP:CE20315
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster F, Reinke et al 2004, list of genes in cluster                             
                                              order                                                                              

Y55B1BR.3 Aff_Y55B1B_119.B P W All gene names: Y55B1BR.3; 3B49; CE24463; WBGene00021913; WP:CE24463
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster order                                                                      

Y57A10A.26 Aff_Y57A10A.BB P W All gene names: Y57A10A.26; Y57A10A.26.1; Y57A10A.26.2; 2M555; CE22631; WBGene00013266; WP:CE22631
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, ViswanathanM et al 2005  S2                                  
                                              sir-2.1 regulated                                                                  

Y59A8B.10 Aff_Y59A8A.G P W All gene names: Y59A8B.10; 5S550; CE26206; WBGene00013347; WP:CE26206
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph                                                               

Y65A5A.1 Aff_Y65A5A.A P W All gene names: Y65A5A.1; 4R164; CE22718; WBGene00013418; WP:CE22718
Y71F9B.4 Aff_Y71F9B_286.B P W All gene names: snr-7; Y71F9B.4; Y71F9B.M; 1D295; CE22871; NM_058631; WBGene00004920; WP:CE22871 WormBase description: small nuclear ribonucleoprotein Sm G (snRNP core protein G)
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke                            
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, oogenesis enriched genes, ViswanathanM et al 2005                            
                                               S2 sir-2.1 regulated                                                              

Y71G12B.15 Aff_Y71G12A_187.A P W All gene names: ubc-3; Y71G12B.15; Y71G12B.15.1; Y71G12B.15.2; 1C173; CE38573; NM_058481; WBGene00006702; WP:CE38573 WormBase description: ubc-3 encodes an E2 ubiquitin-conjugating enzyme orthologous to Saccharomyces cerevisiae and human CDC34 (OMIM:603731) which are involved in regulating protein stability during G1 and G2 cell cycle phase transitions; by homology, UBC-3 is likely required for covalent attachment of ubiquitin to select target proteins to facilitate their degradation; however, as loss of UBC-3 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UBC-3 in C. elegans development and/or behavior is not yet known.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, ViswanathanM et al 2005  S2                                  
                                              sir-2.1 regulated, Wang et al 2003  S4 TransientList,                              
                                              Wang et al 2003  S3  genes pass one-way ANOVA, Wang et                             
                                              al 2003  S4 genes pass two-wayANOVA P0                                             

Y71G12B.6 Aff_Y71G12A_203.E P W All gene names: Y71G12B.6; Y71G12B.6.1; Y71G12B.6.2; 1C269; CE29138; WBGene00022146; WP:CE29138
ZC168.1 Aff_ZC168.1 P W All gene names: ncx-3; ZC168.1; 4L485; CE06567; NM_069583; WBGene00003568; WP:CE06567 WormBase description: ncx-3 encodes a predicted transmembrane Na/Ca exchanger; by homology, NCX-3 is predicted to function as a plasma membrane protein that regulates intracellular calcium homeostasis by moving calcium either into or out of cells, depending upon the net electrochemical force; however, as loss of ncx-3 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of NCX-3 in C. elegans development and/or behavior is not yet known. WormBase CDS description: sodium/calcium exchanger protein like
ZK287.5 Aff_ZK287.5 P W All gene names: Ce-rbx-1; rbx-1; ZK287.5; ZK287.5.1; ZK287.5.2; 5K170; CE06614; NM_073095; WBGene00004320; WP:CE06614 WormBase description: The rbx-1 gene encodes an ortholog of the mammalian RING box protein RBX1 (or ROC1), which interacts with several cullins and is a subunit of both the von Hippel-Lindau (VHL) tumor suppressor complex and of the SCF ubiquitin-ligase (E3) complex. WormBase CDS description: Zinc finger, C3HC4 type (RING finger)
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, intrinsic, Reinke et al                                
                                              2004, wt vs glp-4 enriched genes, Reinke et al 2004,                               
                                              list of genes in cluster order, Reinke et al 2004, list                            
                                              of genes in cluster E, ViswanathanM et al 2005  S2                                 
                                              sir-2.1 regulated                                                                  

ZK328.2 Aff_ZK328.2 P W All gene names: eft-1; ZK328.2; 3H101; CE05066; NM_065907; WBGene00001166; WP:CE05066 WormBase description: elongation factor 2
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt herm vs wt male enriched gen, ViswanathanM                             
                                              et al 2005  S2 sir-2.1 regulated, Wang et al 2003  S5                              
                                              genes common to feeding ANOVA, Wang et al 2003  S3                                 
                                              genes pass one-way ANOVA                                                           

ZK593.5 Aff_ZK593.5 P W All gene names: dnc-1; ZK593.5; 4L696; CE30718; NM_069632; WBGene00001017; WP:CE30718 WormBase description: DNC-1 encodes a dynactin, orthologous to Drosophila GLUED, that is required for pronuclear migration and centrosome separation in one-cell embryos and for the correct alignment of mitotic spindles in early embryos; DNC-1 shares embryonic functions with DNC-2, DHC-1, LIS-1 and NUD-1; DNC-1 is located at cortical microtubule attachment sites. WormBase CDS description: dynactin
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, wt herm vs wt                             
                                              male enriched gen, ViswanathanM et al 2005  S2 sir-2.1                             
                                              regulated                                                                          

ZK593.6 Aff_ZK593.6 P W All gene names: lgg-2; ZK593.6; ZK593.6.1; ZK593.6.2; 4L700; CE06627; NM_069634; WBGene00002981; WP:CE06627 WormBase description: lgg-2 encodes a homolog of the light chain 3 (LC3) subunit of the microtubule-associated proteins 1A and 1B (MAP1A and MAP1B); by homology, LGG-2 is predicted to associate with MAP1A and MAP1B and with microtubules and to perhaps play a role in regulating the microtubule-binding activity of MAP1A and MAP1B; in C. elegans, loss of lgg-2 activity via RNAi does not result in any obvious abnormalities and specifically, does not appear to affect autophagy as required for dauer formation and life-span extension. WormBase CDS description: microtubule-associated protein 1 like
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated, Wang et al 2003  S5 genes common to feeding                             
                                              ANOVA, Wang et al 2003  S3  genes pass one-way ANOVA                               

ZK593.7 Aff_ZK593.7 P W All gene names: lsm-7; ZK593.7; ZK593.7.1; ZK593.7.2; 4L699; CE06628; NM_069633; WBGene00003081; WP:CE06628 WormBase description: Yeast JTA107 like
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, intrinsic, Reinke et al                                
                                              2004, wt vs glp-4 enriched genes, Reinke et al 2004, GO                            
                                              categories, ViswanathanM et al 2005  S2 sir-2.1                                    
                                              regulated                                                                          

ZK829.9 Aff_ZK829.9 P W All gene names: ZK829.9; 4M735; CE06657; WBGene00014097; WP:CE06657 WormBase description: glucose transporter
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

ZK909.4 Aff_ZK909.4 P W All gene names: ces-2; ZK909.4; 1P559; CE15479; NM_061209; WBGene00000469; WP:CE15479 WormBase description: ces-2 encodes a basic region leucine-zipper (bZIP) transcription factor, most similar in sequence and binding specificity to the PAR (proline- and acid-rich) subfamily of bZIP proteins; ces-2 is required to activate programmed cell death in the sister cells of the serotoninergic neurosecretory motor (NSM) neurons, and is transcriptionally inhibited by activated LET-60(G12V). WormBase CDS description: albumin D-binding protein like
                                              
Member of lists (Publications lists):
                                              Portman et al 2004  T1 newly found                                
                                              ray-genes in25c, Portman et al 2004  T1 25 candidate                               
                                              ray genes, Reinke et al 2004, list of genes in cluster                             
                                              order, Reinke et al 2004, list of genes in cluster E,                              
                                              Romagnolo et al 2002  Fig3b TF                                                     

ZK973.11 Aff_ZK973_14.A P W All gene names: ZK973.11; 1E948; CE29654; WBGene00022836; WP:CE29654 WormBase description: thioredoxin
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt herm vs wt male enriched gen, Reinke et al                             
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated                                                         

ZK973.9 Aff_ZK973_14.C P W All gene names: ZK973.9; ZK973.C; 1E938; CE23479; WBGene00022835; WP:CE23479
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Non dauer genes                                 
                                              P<0.05, Reinke et al 2004, fem1 enriched genes, Reinke                             
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, oogenesis enriched genes, Reinke et al 2004, wt                              
                                              herm vs wt male enriched gen, Reinke et al 2004, GO                                
                                              categories, ViswanathanM et al 2005  S2 sir-2.1                                    
                                              regulated