Lund et al 2002 Fig2A insulin-related, 12 genes

Gene list file name:Lund2002_Aging_time_course.Fig2A_insulin.txt
Type of gene identifier:Cosmid name
Description:Lund et al 2002 Fig2A insulin-related genes  
Organism:Caenorhabditis elegans (nematode)
Gene list type:Experimental

Gene name             Source Gene ID          Annotation                                                  Date       Added by    

C17C3.4 ins-11 P W All gene names: ins-11; C17C3.4; 2F847; CE04024; NM_062670; WBGene00002094; WP:CE04024 WormBase description: ins-11 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-11 is one of 38 insulin-like peptides in C. elegans and is expressed in the labial sensory neurons, the nerve ring, and other neurons; although the precise role of INS-11 in C. elegans development is not yet clear, loss of INS-11 function via RNA-mediated interference can result in animals that are smaller than wild type (Sma). WormBase CDS description: 7TM chemoreceptor, ins family
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

F56F3.6 ins-17 P W All gene names: Ceinsulin-2; ins-17; F56F3.6; F56F3.6.1; F56F3.6.2; 3F566; CE00681; NM_065510; WBGene00002100; WP:CE00681
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, IVb male soma                                  
                                              enriched genes, ViswanathanM et al 2005  S2 sir-2.1                                
                                              regulated, ViswanathanM et al 2005  S2 daf-16                                      
                                              Resveratrol                                                                        

M04D8.1 ins-21 P W All gene names: ins-21; M04D8.1; 3L113; CE35999; NM_066821; WBGene00002104; WP:CE35999
                                              
Member of lists (Publications lists):
                                              Murphy et al 2003  Fig2 Class2 shorten                            
                                              lifespan                                                                           

M04D8.2 ins-22 P W All gene names: ins-22; M04D8.2; 3L115; CE00577; NM_066822; WBGene00002105; WP:CE00577 WormBase description: ins-22 encodes predicted type-alpha insulin-like molecule that lacks a C peptide domain and does not have an A6/A11 disulfide bond; expressed throughout development in some neurons beginning in the four-fold elongated embryo.
M04D8.3 ins-23 P W All gene names: ins-23; M04D8.3; 3L117; CE00578; NM_066823; WBGene00002106; WP:CE00578 WormBase description: ins-23 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-23 is one of 38 insulin-like peptides in C. elegans, and is expressed in amphid sensory neurons, labial neurons, the nerve ring, and ventral nerve cord neurons; as loss of INS-23 function via RNA-mediated interference does not results in any abnormalities, the precise role of INS-23 in C. elegans development is not yet clear.
                                              
Member of lists (Publications lists):
                                              Lund et al 2002  Fig4 Mount 15                                    

T28B8.2 ins-18 P W All gene names: Ceinsulin-1; igf-1; ins-18; T28B8.2; 1I725; CE27217; NM_059830; WBGene00002101; WP:CE27217 WormBase description: The ins-18 gene encodes an insulin/IGF-like peptide that may act in a common pathway with daf-2 to regulate lifespan. WormBase CDS description: insulin-like growth factor I like
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  T2 lifespan and                                 
                                              Dauer, Murphy et al 2003  Fig2 Class1 elongate                                     
                                              lifespan, Reinke et al 2004, wt herm vs wt herm                                    
                                              enriched gen, Reinke et al 2004, IVb male soma enriched                            
                                              genes, Wang et al 2003  S3  genes pass one-way ANOVA,                              
                                              Wang et al 2003  S4 Dauer Enriched, Wang et al 2003  S4                            
                                              genes pass two-wayANOVA P0                                                         

ZK1251.2 ins-7 P W All gene names: ins-7; ZK1251.2; 4K446; CE03849; NM_069316; WBGene00002090; WP:CE03849 WormBase description: ins-7 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-7 is one of 38 insulin-like peptides in C. elegans and is expressed in the amphid sensory neurons, labial neurons, the nerve ring, and other neurons; the precise role of INS-7 in C. elegans development is not yet clear as loss of function does not result in a mutant phenotype.
                                              
Member of lists (Publications lists):
                                              Murphy et al 2003  Fig2 Class2 shorten                            
                                              lifespan, Reinke et al 2004, list of genes in cluster                              
                                              order, Reinke et al 2004, mixed sperm soma, Reinke et                              
                                              al 2004, fem3 enriched genes, ViswanathanM et al 2005                              
                                              S2 sir-2.1 regulated                                                               

ZK75.1 ins-4 P W All gene names: ins-4; ZK75.1; 2G283; CE02100; NM_062795; WBGene00002087; WP:CE02100 WormBase description: 7TM chemoreceptor, ins family
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, mixed sperm soma,                              
                                              Reinke et al 2004, fem3 enriched genes                                             

ZK75.2 ins-2 P W All gene names: ins-2; ZK75.2; 2G277; CE02101; NM_062793; WBGene00002085; WP:CE02101 WormBase description: 7TM chemoreceptor, ins family
                                              
Member of lists (Publications lists):
                                              Lund et al 2002  Fig1 aging-regulated                             
                                              genes, ViswanathanM et al 2005  S2 sir-2.1 regulated                               

ZK75.3 ins-3 P W All gene names: ins-3; ZK75.3; 2G278; CE02102; NM_062794; WBGene00002086; WP:CE02102 WormBase description: ins-3 encodes one of several insulin-related peptides; INS-3 is classified as a Type-beta insulin based on the predicted arrangement of disulfide bonds; gfp gene fusions with the promoter and enhancer regions indicate that INS-3 is expressed in some amphid sensory neurons. WormBase CDS description: 7TM chemoreceptor, ins family
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 daf-16                                
                                              Resveratrol                                                                        

ZK84.3 ins-5 P W All gene names: ins-5; ZK84.3; 2G285; CE39198; NM_062796; WBGene00002088; WP:CE39198 WormBase description: ins-5 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-5 is one of 38 insulin-like peptides in C. elegans and is expressed in the amphid sensory neurons, labial neurons, the nerve ring, other neurons, and the vulva; the precise role of INS-5 in C. elegans development is not yet clear as loss of function does not result in a mutant phenotype. WormBase CDS description: 7TM chemoreceptor, ins family
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 daf-16                                
                                              Resveratrol                                                                        

ZK84.6 ins-6 P W All gene names: ins-6; ZK84.6; 2G287; CE15253; NM_062797; WBGene00002089; WP:CE15253 WormBase description: ins-6 encodes predicted type-beta insulin-like molecule that lacks a C peptide domain; expressed throughout development and in some neurons beginning in the two-fold elongated embryo. WormBase CDS description: 7TM chemoreceptor, ins family
                                              
Member of lists (Publications lists):
                                              Romagnolo et al 2002  Fig3b signaling,                            
                                              Wang et al 2003  S3  genes pass one-way ANOVA, Wang et                             
                                              al 2003  S4 Dauer Enriched, Wang et al 2003  S4 genes                              
                                              pass two-wayANOVA P0