McElwee et al 2003 T1 targets of daf-16, 35 genes

Gene list file name:McElwee2003.T1_targetsof_daf-16.txt
Type of gene identifier:MA primer pair (sjj)
Description:McElwee et al 2003 Table1: targets of daf-16  
Organism:Caenorhabditis elegans (nematode)
Gene list type:Experimental

Gene name             Source Gene ID          Annotation                                                  Date       Added by    

B0222.9 B0222.9 P W All gene names: B0222.9; 5J650; CE32787; WBGene00015057; WP:CE32787 WormBase description: xanthine dehydrogenase
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, ViswanathanM et al 2005  S2 sir-2.1 regulated                              

C05C10.4 C05C10.4 P W All gene names: C05C10.4; 2K223; CE17370; WBGene00007331; WP:CE17370 WormBase description: acid phosphatase
                                              
Member of lists (Publications lists):
                                              Kwon et al 2004  T1 late-repression                               
                                              Ethanol-respon, McElwee et al 2003  T1 targets of                                  
                                              daf-16, Reinke et al 2004, list of genes in cluster A,                             
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, GO categories, Reinke et al 2004,                               
                                              herm soma enriched genes, ViswanathanM et al 2005  S2                              
                                              sir-2.1 regulated                                                                  

C08A9.1 C08A9.1 P W All gene names: sod-3; C08A9.1; CE08002; MnSOD; NM_078363; WBGene00004932; WP:CE08002; XR707 WormBase description: sod-3 encodes a iron/manganese superoxide dismutase, predicted to be mitochondrial, that might defend against oxidative stress and promote normal lifespan; sod-3 mRNA levels are diminished by mutation of daf-16, and heterologously expressed SOD-3 in E. coli protects against methyl viologen-induced oxidative stress. WormBase CDS description: superoxide dismutase
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  T2 lifespan and                                 
                                              Dauer, Lund et al 2002  Fig4 Mount 15, McElwee et al                               
                                              2003  T1 targets of daf-16, McElwee et al 2003  Fig4                               
                                              daf-16 target lifspan, Murphy et al 2003  Fig2 Class1                              
                                              elongate lifespan, Reinke et al 2004, fem1 enriched                                
                                              genes, Reinke et al 2004, mixed oogenesis soma,                                    
                                              ViswanathanM et al 2005  S2 daf-16 Resveratrol,                                    
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated, Wang et                             
                                              al 2003  S6 removed genes of contamination                                         

C17B7.7 C17B7.7 P W All gene names: C17B7.7; 5D807; CE39895; WBGene00015881; WP:CE39895
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, Reinke et al 2004, fem1 enriched genes, Reinke                             
                                              et al 2004, mixed oogenesis soma, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated                                                         

C26H9A.1 C26H9A.1 P W All gene names: vha-7; C26H9A.1; C26H9A.B; 4N413; CE30882; NM_070018; WBGene00006916; WP:CE30882
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, Reinke et al 2004, list of genes in cluster F,                             
                                              Reinke et al 2004, fem1 enriched genes, Reinke et al                               
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, wt herm vs wt male enriched gen, Reinke et al                                
                                              2004, mixed oogenesis soma                                                         

C33H5.10 C33H5.10 P W All gene names: C33H5.10; 4I548; CE26878; WBGene00016377; WP:CE26878
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, McElwee et al 2003  T1 targets of                            
                                              daf-16, Reinke et al 2004, list of genes in cluster                                
                                              order, Reinke et al 2004, list of genes in cluster E,                              
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

C34B4.4 C34B4.2 P W All gene names: C34B4.4; 5N573; CE36689; WBGene00007909; WP:CE36689
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16                                                                             

C50B8.2 C50B8.2 P W All gene names: bir-2; C50B8.2; 5O49; CE08882; NM_073961; WBGene00000250; WP:CE08882 WormBase description: The bir-2 gene encodes a protein with two BIR domains that may be involved in apoptosis. WormBase CDS description: Inhibitor of Apoptosis domain.
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, Reinke et al 2004, fem1 enriched genes, Reinke                             
                                              et al 2004, Fig2b shared gemlines, Reinke et al 2004,                              
                                              list of genes in cluster order, Reinke et al 2004,                                 
                                              oogenesis enriched genes, Reinke et al 2004, wt vs                                 
                                              glp-4 enriched genes, Reinke et al 2004, wt males vs                               
                                              glp4 male enriched , Reinke et al 2004, wt herm vs wt                              
                                              male enriched gen, Reinke et al 2004, list of genes in                             
                                              cluster E, ViswanathanM et al 2005  S2 sir-2.1                                     
                                              regulated                                                                          

D2096.4 D2096.4 P W All gene names: sqv-1; D2096.4; D2096.4.1; D2096.4.2; 4J127; CE04302; NM_069017; WBGene00005019; WP:CE04302 WormBase description: sqv-1 encodes a UDP-glucuronic acid decarboxylase, biochemically active in vitro, that is required for cytokinesis of one-cell embryos and for vulval morphogenesis; SQV-1 is coexpressed with the nucleotide-sugar transporter homolog SQV-7 in in the vulva and in oocytes; SQV-1 colocalizes with SQV-5 and SQV-7 to punctate foci (probably the Golgi apparatus) in the cytoplasm of the vulva, the uterus and oocytes, within which SQV-1 may act to promote the biosynthesis of chondroitin glycosaminoglycans; the common requirement for SQV-1 in both cytokinesis and morphogenesis may be to promote filling an extracellular space with hygroscopic proteoglycans (either in the eggshell, or underneath the L4 cuticle), which in turn may cause the space to fill with fluid.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, McElwee et al 2003  T1 targets of                            
                                              daf-16, Reinke et al 2004, list of genes in cluster                                
                                              order, Reinke et al 2004, intrinsic, Reinke et al 2004,                            
                                              wt vs glp-4 enriched genes, Reinke et al 2004, wt herm                             
                                              vs wt male enriched gen, Reinke et al 2004, GO                                     
                                              categories, Reinke et al 2004, herm soma enriched                                  
                                              genes, Reinke et al 2004, list of genes in cluster E,                              
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated, Wang et                             
                                              al 2003  S5 genes common to feeding ANOVA, Wang et al                              
                                              2003  S3  genes pass one-way ANOVA                                                 

F17B5.1 F17B5.1 P W All gene names: F17B5.1; 1N779; CE15865; WBGene00008905; WP:CE15865
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, Murphy et al 2003  Fig2 Class1 elongate                                    
                                              lifespan, Reinke et al 2004, list of genes in cluster                              
                                              A, Reinke et al 2004, list of genes in cluster order,                              
                                              Reinke et al 2004, wt herm vs wt male enriched gen,                                
                                              Reinke et al 2004, herm soma enriched genes, Reinke et                             
                                              al 2004, GO categories, ViswanathanM et al 2005  S2                                
                                              daf-16 Resveratrol                                                                 

F29D10.4 F29D10.4 P W All gene names: hum-1; F29D10.4; 1J422; CE05763; NM_059992; WBGene00002035; WP:CE05763 WormBase description: myosin
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McElwee et al 2003  T1 targets of daf-16,                                
                                              Reinke et al 2004, fem1 enriched genes, Reinke et al                               
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, mixed oogenesis soma, Reinke et al 2004, list of                             
                                              genes in cluster E, ViswanathanM et al 2005  S2 sir-2.1                            
                                              regulated                                                                          

F35E8.11 F35E8.11 P W All gene names: cdr-1; F35E8.11; 5Q403; CE15961; NM_074585; WBGene00000412; WP:CE15961 WormBase description: cdr-1 encodes a member of the cadmium-inducible lysosomal family that affects susceptibility to cadmium toxicity; expressed in intestinal cells. WormBase CDS description: glutathione S-transferases
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, Wang et al 2003  S5 genes common to feeding                                
                                              ANOVA, Wang et al 2003  S3  genes pass one-way ANOVA                               

F36G9.14 F36G9.14 P W All gene names: fbxa-99; F36G9.14; 5Q458; CE15991; WBGene00009490; WP:CE15991 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Non dauer genes                                 
                                              P<0.05, McElwee et al 2003  T1 targets of daf-16,                                  
                                              Romagnolo et al 2002  Fig3b Unkown                                                 

F40F4.3 F40F4.3 P W All gene names: lbp-1; F40F4.3; CE04533; NM_076156; WBGene00002253; WP:CE04533; XD879 WormBase description: fatty acid-binding protein
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, Reinke et al 2004, list of genes in cluster                                
                                              order, ViswanathanM et al 2005  S2 sir-2.1 regulated                               

F43E2.5 F43E2.5 P W All gene names: F43E2.5; 2H652; CE07241; WBGene00018393; WP:CE07241 WormBase description: F43E2.5 encodes a methionine sulfoxide-S-reductase (MsrA) with experimentally confirmed activity.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, McElwee et al 2003  T1 targets of daf-16,                                 
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

F46C3.2 F46C3.2 P W All gene names: F46C3.2; CE03341; WBGene00009777; WP:CE03341; XM36
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, Reinke et al 2004, herm soma enriched genes                                

F48G7.5 F48G7.5 P W All gene names: F48G7.5; 5B100; CE10762; WBGene00018616; WP:CE10762
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, Reinke et al 2004, list of genes in cluster                                
                                              order, Reinke et al 2004, list of genes in cluster C,                              
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated, Wang et                             
                                              al 2003  S3  genes pass one-way ANOVA, Wang et al 2003                             
                                              S4 Dauer Enriched, Wang et al 2003  S4 genes pass                                  
                                              two-wayANOVA P0                                                                    

F48G7.8 F48G7.8 P W All gene names: F48G7.8; 5B106; CE10768; WBGene00018619; WP:CE10768
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, Reinke et al 2004, list of genes in cluster                                
                                              order, Reinke et al 2004, list of genes in cluster C,                              
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated, Wang et                             
                                              al 2003  S3  genes pass one-way ANOVA, Wang et al 2003                             
                                              S4 Dauer Enriched, Wang et al 2003  S4 genes pass                                  
                                              two-wayANOVA P0                                                                    

F49E11.9 F49E11.9 P W All gene names: scl-1; F49E11.9; 4N819; CE05905; NM_070101; WBGene00004742; WP:CE05905 WormBase description: testis-specific protein TPX-1 like
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, Murphy et al 2003  Fig2 Class1 elongate                                    
                                              lifespan, ViswanathanM et al 2005  S2 sir-2.1 regulated                            

F54C8.7 F54C8.7 P W All gene names: F54C8.7; 3K542; CE28833; CE33524; WBGene00010040; WP:CE28833; WP:CE33524
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, McElwee et al 2003  T1 targets of                            
                                              daf-16, ViswanathanM et al 2005  S2 sir-2.1 regulated                              

F55G11.4 F55G11.4 P W All gene names: F55G11.4; 4N739; CE18750; WBGene00010124; WP:CE18750
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, ViswanathanM et al 2005  S2 daf-16 Resveratrol                             

F57B1.4 F57B1.4 P W All gene names: col-160; F57B1.4; F57B1.4.1; F57B1.4.2; F57B1.4.3; 5N682; CE31962; NM_073883; WBGene00000733; WP:CE31962 WormBase description: collagen
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, ViswanathanM et al 2005  S2 sir-2.1 regulated                              

H12D21.1 H12D21.1 P W All gene names: nspa-1; H12D21.1; 5P366; CE15223; NM_074268; WBGene00010377; WP:CE15223
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, Murphy et al 2003  Fig2 Class1 elongate                                    
                                              lifespan, Reinke et al 2004, list of genes in cluster                              
                                              order, Reinke et al 2004, spermatogenesis enriched                                 
                                              genes, Reinke et al 2004, fem3 enriched genes, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, wt males vs glp4 male enriched , Reinke et al                                
                                              2004, list of genes in cluster D, Reinke et al 2004,                               
                                              shared sperm, ViswanathanM et al 2005  S2 daf-16                                   
                                              Resveratrol, ViswanathanM et al 2005  S2 sir-2.1                                   
                                              regulated                                                                          

K03H1.4 K03H1.4 P W All gene names: K03H1.4; 3L17; CE00475; WBGene00010539; WP:CE00475 WormBase description: Transthyretin-like family
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, Reinke et al 2004, list of genes in cluster A,                             
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated, Wang et                             
                                              al 2003  S3  genes pass one-way ANOVA, Wang et al 2003                             
                                              S4 genes pass two-wayANOVA P0, Wang et al 2003  S4                                 
                                              Dauer Enriched, Zhang et al 2002, T1 mec-3 dependent                               
                                              genes, Zhang et al. 2002, Fig2b overexpressed in                                   
                                              mec-3MT                                                                            

K03H1.6 K03H1.6 P W All gene names: ttr-1; K03H1.6; 3L19; CE00476; WBGene00010541; WP:CE00476 WormBase description: Transthyretin-like family
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, Wang et al 2003  S3  genes pass one-way ANOVA,                             
                                              Wang et al 2003  S4 Dauer Enriched, Wang et al 2003  S4                            
                                              genes pass two-wayANOVA P0                                                         

K07B1.4 K07B1.4 P W All gene names: K07B1.4; K07B1.4b.1; K07B1.4b.2; 5J811; CE11882; CE27391; WBGene00019464; WP:CE11882; WP:CE27391
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, McElwee et al 2003  T1 targets of daf-16,                                 
                                              Murphy et al 2003  Fig2 Class1 elongate lifespan,                                  
                                              Reinke et al 2004, wt herm vs wt male enriched gen,                                
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

M60.4 M60.3 P W All gene names: M60.4; M60.4b.1; M60.4b.2; M60.4b.3; M60.4b.4; CE02832; CE34063; WBGene00019780; WP:CE02832; WP:CE34063; XI852
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, Reinke et al 2004, IVb male soma enriched                                  
                                              genes, Wang et al 2003  S6 removed genes of                                        
                                              contamination                                                                      

R08E5.2 R08E5.2 P W All gene names: R08E5.2; R08E5.2b.1; R08E5.2b.2; R08E5.2b.3; R08E5.2b.4; 5E250; CE12574; CE33294; CE33295; WBGene00019962; WP:CE12574; WP:CE33294; WP:CE33295 WormBase description: cysteine synthase
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Non dauer genes                                 
                                              P<0.05, McElwee et al 2003  T1 targets of daf-16,                                  
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated, Wang et                             
                                              al 2003  S6 removed genes of contamination                                         

T13F2.1 T13F2.1 P W All gene names: fat-4; T13F2.1; T13F2.1.1; T13F2.1.2; T13F2.1.3; 4K565; CE25113; NM_069350; WBGene00001396; WP:CE25113 WormBase description: fat-4 encodes a delta-5 fatty acid desaturase; when expressed heterologously in S. cerevisiae, FAT-4 converts di-homo-gamma-linolenic acid (20:3delta8,11,14) to arachidonic acid (20:4delta5,8,11,14), an important precursor in eicosanoid metabolism, as well as on other fatty acids (C18 to C20); FAT-4 is is required in vivo for delta-5 unsaturated fatty acid synthesis. WormBase CDS description: cytochrome B5 containing fusion protein
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, ViswanathanM et al 2005  S2 sir-2.1 regulated                              

W01C9.2 W01C9.2 P W All gene names: W01C9.2; 2I829; CE02368; WBGene00012176; WP:CE02368
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, ViswanathanM et al 2005  S2 sir-2.1 regulated                              

W02D3.6 W02D3.6 P W All gene names: tag-194; W02D3.6; 1H306; CE14428; WBGene00007057; WBGene00020934; WP:CE14428 WormBase description: ADP, ATP carrier protein
                                              
Member of lists (Publications lists):
                                              Golden et al 2004, N2 vs daf-2                                    
                                              different genes at , McElwee et al 2003  T1 targets of                             
                                              daf-16, Reinke et al 2004, male germline, Reinke et al                             
                                              2004, wt males vs glp4 male enriched , Reinke et al                                
                                              2004, wt herm vs wt herm enriched gen, ViswanathanM et                             
                                              al 2005  S2 daf-16 Resveratrol                                                     

Y52B11A.9 Y52B11A.9 P W All gene names: Y52B11A.9; 1L626; CE20297; WBGene00013128; WP:CE20297
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, McElwee et al 2003  T1 targets of daf-16,                                 
                                              Reinke et al 2004, list of genes in cluster F, Reinke                              
                                              et al 2004, fem1 enriched genes, Reinke et al 2004,                                
                                              list of genes in cluster order, Reinke et al 2004,                                 
                                              oogenesis enriched genes, Reinke et al 2004, wt vs                                 
                                              glp-4 enriched genes, Reinke et al 2004, GO categories,                            
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

ZC412.6 ZC412.6 P W All gene names: nspa-5; ZC412.6; 5P359; CE15221; NM_074263; WBGene00013887; WP:CE15221
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, Reinke et al 2004, wt vs glp-4 enriched genes,                             
                                              Reinke et al 2004, wt males vs glp4 male enriched ,                                
                                              Reinke et al 2004, spermatogenesis enriched genes,                                 
                                              Reinke et al 2004, fem3 enriched genes, Reinke et al                               
                                              2004, shared sperm                                                                 

ZC412.7 ZC412.7 P W All gene names: nspa-3; ZC412.7; 5P362; NM_074265; WBGene00013888
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, Reinke et al 2004, list of genes in cluster                                
                                              order, Reinke et al 2004, spermatogenesis enriched                                 
                                              genes, Reinke et al 2004, fem3 enriched genes, Reinke                              
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, wt males vs glp4 male enriched , Reinke et al                                
                                              2004, list of genes in cluster D, Reinke et al 2004,                               
                                              shared sperm, ViswanathanM et al 2005  S2 daf-16                                   
                                              Resveratrol, ViswanathanM et al 2005  S2 sir-2.1                                   
                                              regulated                                                                          

ZK742.4 ZK742.4 P W All gene names: ZK742.4; 5I290; CE07640; WBGene00022814; WP:CE07640
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  T1 targets of                                 
                                              daf-16, ViswanathanM et al 2005  S2 daf-16 Resveratrol,                            
                                              Wang et al 2003  S6 removed genes of contamination