McElwee et al 2003 Fig4 daf-16 target lifspan, 5 genes

Gene list file name:McElwee2003.Fig4_daf-16_target_lifspan.txt
Type of gene identifier:MA primer pair (sjj)
Description:McElwee et al 2003 Fig4 daf-16 target lifspan genes  
Organism:Caenorhabditis elegans (nematode)
Gene list type:Experimental

Gene name             Source Gene ID          Annotation                                                  Date       Added by    

C08A9.1 C08A9.1 P W All gene names: sod-3; C08A9.1; CE08002; MnSOD; NM_078363; WBGene00004932; WP:CE08002; XR707 WormBase description: sod-3 encodes a iron/manganese superoxide dismutase, predicted to be mitochondrial, that might defend against oxidative stress and promote normal lifespan; sod-3 mRNA levels are diminished by mutation of daf-16, and heterologously expressed SOD-3 in E. coli protects against methyl viologen-induced oxidative stress. WormBase CDS description: superoxide dismutase
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  T2 lifespan and                                 
                                              Dauer, Lund et al 2002  Fig4 Mount 15, McElwee et al                               
                                              2003  T1 targets of daf-16, McElwee et al 2003  Fig4                               
                                              daf-16 target lifspan, Murphy et al 2003  Fig2 Class1                              
                                              elongate lifespan, Reinke et al 2004, fem1 enriched                                
                                              genes, Reinke et al 2004, mixed oogenesis soma,                                    
                                              ViswanathanM et al 2005  S2 daf-16 Resveratrol,                                    
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated, Wang et                             
                                              al 2003  S6 removed genes of contamination                                         

R13H8.1 R13H8.1 P W All gene names: daf-16; daf-17; R13H8.1; R13H8.1e.1; R13H8.1e.2; 1L351; CE28771; CE28772; CE28773; CE33160; CE38722; CE38723; WBGene00000912; WP:CE28771; WP:CE28772; WP:CE28773; WP:CE33160; WP:CE38722; WP:CE38723 WormBase description: daf-16 encodes a transcription factor of the HNF-3/forkhead family (orthologous to mammalian AFX, FKHR, and FKHRL1) that acts in an insulin-mediated pathway to affect dauer formation, and that also affects life span and reproduction; DAF-16 can interact with CBP-1 in vitro, and interacts genetically both with other genes in the insulin signaling and with the nuclear hormone receptor DAF-12; daf-16 is broadly expressed in most if not all cells (though expression in the pharynx and in the somatic gonad differ for the two isoforms); DAF-16 is homologous to human FORKHEAD BOX O1A (FOXO1A), which when mutated leads to rhabdomyosarcoma (OMIM:136533).
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  T2 lifespan and                                 
                                              Dauer, McElwee et al 2003  Fig4 daf-16 target lifspan,                             
                                              Wang et al 2003  S4 TransientList, Wang et al 2003  S3                             
                                              genes pass one-way ANOVA, Wang et al 2003  S4 Dauer                                
                                              Enriched, Wang et al 2003  S4 genes pass two-wayANOVA                              
                                              P0, Wang et al 2003  Fig7 daf-16                                                   

ZC334.2 ZC334.2 P W All gene names: ins-30; ZC334.2; 1O626; CE19308; NM_061043; WBGene00002113; WP:CE19308
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  Fig4 daf-16 target                            
                                              lifspan, Reinke et al 2004, list of genes in cluster A,                            
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

ZK384.3 ZK384.3 P W All gene names: ZK384.3; 5T204; CE20430; WBGene00013973; WP:CE20430 WormBase description: Eukaryotic aspartyl proteases
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  Fig4 daf-16 target                            
                                              lifspan, Murphy et al 2003  Fig2 Class1 elongate                                   
                                              lifespan                                                                           

ZK430.3 ZK430.3 P W All gene names: sod-5; ZK430.3; 2E709; CE05080; NM_062378; WBGene00007036; WP:CE05080 WormBase description: superoxide dismutase
                                              
Member of lists (Publications lists):
                                              McElwee et al 2003  Fig4 daf-16 target                            
                                              lifspan, Reinke et al 2004, intrinsic, Reinke et al                                
                                              2004, wt vs glp-4 enriched genes, Reinke et al 2004, GO                            
                                              categories, Wang et al 2003  S6 removed genes of                                   
                                              contamination