Jiang et al 2001 Fig3 Rb complex genes, 9 genes

Gene list file name:Jiang2001.Fig3_Rb-genes.txt
Type of gene identifier:Cosmid name
Description:Jiang et al 2001 Fig3 Rb tumor suppressor complex genes  
Organism:Caenorhabditis elegans (nematode)
Gene list type:Experimental

Gene name             Source Gene ID          Annotation                                                  Date       Added by    

C32F10.2 lin-35 P W All gene names: lin-35; C32F10.2; 1G391; CE24823; NM_059285; WBGene00003020; WP:CE24823 WormBase description: lin-35 encodes the C. elegans retinoblastoma protein (Rb) ortholog; lin-35 was first identified in screens for synthetic multivulva (synMuv) genes and as a class B synMuv gene, functions redundantly with class A genes to antagonize Ras signaling and negatively regulate vulval development; in addition, lin-35 activity is required redundantly with: 1) pha-1 and ubc-18 for early steps in pharyngeal morphogenesis, 2) fzr-1 for normal patterns of postembryonic proliferation, 3) xnp-1 for somatic gonad development, and 4) psa-1 for fertility and embryonic and larval development; on its own, lin-35 is also required for wild-type levels of fertility; LIN-35 is expressed broadly in embryos and L1 larvae, but in later larvae and adults is detected in vulval precursor cells and their descendants as well as a subset of head and tail cells.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, list of genes in cluster                                 
                                              order, Reinke et al 2004, oogenesis enriched genes,                                
                                              Reinke et al 2004, wt vs glp-4 enriched genes, Reinke                              
                                              et al 2004, wt herm vs wt male enriched gen, Reinke et                             
                                              al 2004, list of genes in cluster E, ViswanathanM et al                            
                                              2005  S2 daf-16 Resveratrol, ViswanathanM et al 2005                               
                                              S2 sir-2.1 regulated                                                               

C53A5.3 hda-1 P W All gene names: gon-10; hda-1; C53A5.3; C53A5.3.1; C53A5.3.2; 5P7; CE08952; NM_074198; WBGene00001834; WP:CE08952 WormBase description: The hda-1 gene encodes a histone deacetylase 1, similar to histone deacetylases RPD3 from yeast and fly; maternal and zygotic expression of hda-1 is required for embryonic viability, and zygotic expression of hda-1 is also required for gonadogenesis and vulval development. WormBase CDS description: Yeast RPD3 protein like
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, list of genes in cluster F,                            
                                              Reinke et al 2004, fem1 enriched genes, Reinke et al                               
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, oogenesis enriched genes, Reinke et al 2004, wt                              
                                              vs glp-4 enriched genes, Reinke et al 2004, wt herm vs                             
                                              wt male enriched gen, ViswanathanM et al 2005  S2                                  
                                              sir-2.1 regulated                                                                  

F44B9.6 lin-36 P W All gene names: lin-36; F44B9.6; 3J106; CE30992; NM_066346; WBGene00003021; WP:CE30992
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster F, Reinke et al 2004, fem1 enriched genes,                                 
                                              Reinke et al 2004, wt vs glp-4 enriched genes, Reinke                              
                                              et al 2004, list of genes in cluster order, Reinke et                              
                                              al 2004, oogenesis enriched genes, Reinke et al 2004,                              
                                              wt herm vs wt male enriched gen                                                    

F49E12.6 F49E12.6 P W All gene names: F49E12.6; 2I705; CE37018; WBGene00009899; WP:CE37018 WormBase description: The F49E12.6 gene encodes a protein with two E2F domains that may be involved in apoptosis. WormBase CDS description: RBB3 like protein
                                              
Member of lists (Publications lists):
                                              Jiang et al 2001  Fig3 Rb complex                                 
                                              genes, Reinke et al 2004, list of genes in cluster                                 
                                              order, Reinke et al 2004, list of genes in cluster B,                              
                                              ViswanathanM et al 2005  S2 daf-16 Resveratrol                                     

K07A1.11 rba-1 P W All gene names: rba-1; K07A1.11; 1K194; CE11860; NM_060150; WBGene00004312; WP:CE11860 WormBase description: retinablastoma-binding protein RBAP46 like
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, fem1 enriched                                  
                                              genes, Reinke et al 2004, wt vs glp-4 enriched genes,                              
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, oogenesis enriched genes, Reinke et                             
                                              al 2004, wt herm vs wt male enriched gen, Reinke et al                             
                                              2004, list of genes in cluster E, ViswanathanM et al                               
                                              2005  S2 sir-2.1 regulated                                                         

K07A1.12 rba-2 P W All gene names: lin-53; rba-2; K07A1.12; K07A1.12.1; K07A1.12.2; 1K196; CE16234; NM_060151; WBGene00003036; WP:CE16234 WormBase description: chromatin assembly factor 1 P55 subunit like
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, list of genes in cluster F,                            
                                              Reinke et al 2004, fem1 enriched genes, Reinke et al                               
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, oogenesis enriched genes, Reinke et al 2004, wt                              
                                              vs glp-4 enriched genes, Reinke et al 2004, wt herm vs                             
                                              wt male enriched gen, ViswanathanM et al 2005  S2                                  
                                              sir-2.1 regulated                                                                  

Y102A5C.18 Y102A5C.18 P W All gene names: efl-1; mex-2; Y102A5C.18; Y102A5C.18.1; Y102A5C.18.2; 5R440; CE20390; NM_074888; WBGene00001161; WP:CE20390 WormBase description: efl-1 encodes a homolog of mammalian E2F that is required for embryonic asymmetry and that functions as a transcriptional repressor; during vulval development, efl-1, a class B synMuv gene, acts with class B synMuv genes dpl-1 and lin-35/Rb to antagonize receptor tyrosine kinase and Ras-mediated signaling; EFL-1 also negatively regulates the G1 to S phase cell cycle transition.
                                              
Member of lists (Publications lists):
                                              Jiang et al 2001  Fig3 Rb complex                                 
                                              genes, McCarroll et al 2004  SFig1-4 conserved w/                                  
                                              Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke                            
                                              et al 2004, list of genes in cluster order, Reinke et                              
                                              al 2004, oogenesis enriched genes, Reinke et al 2004,                              
                                              wt vs glp-4 enriched genes, Reinke et al 2004, wt herm                             
                                              vs wt male enriched gen, Reinke et al 2004, list of                                
                                              genes in cluster E, ViswanathanM et al 2005  S2 sir-2.1                            
                                              regulated                                                                          

ZK637.7 lin-9 P W All gene names: lin-9; ZK637.7; 3J990; CE28194; CE28195; WBGene00002998; WP:CE28194; WP:CE28195 WormBase description: lin-9 encodes two novel proteins that are conserved amongst C. elegans, Drosophila, plants, and vertebrates; lin-9 activity is required redundantly with activity of the synMuv A genes, such as lin-8, for negative regulation of the RTK/Ras-mediated signal transduction pathway that controls vulval development; in addition, lin-9 activity is required non-redundantly for hermaphrodite gonadal sheath cell development (and thus, reproduction), as well as for development of the male reproductive system including the male sensory rays and spicules.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster F, Reinke et al 2004, list of genes in                                  
                                              cluster order, Reinke et al 2004, intrinsic, Reinke et                             
                                              al 2004, wt vs glp-4 enriched genes, Reinke et al 2004,                            
                                              wt herm vs wt male enriched gen, ViswanathanM et al                                
                                              2005  S2 daf-16 Resveratrol, ViswanathanM et al 2005                               
                                              S2 sir-2.1 regulated                                                               

ZK662.4 lin-15B P W All gene names: lin-15B; ZK662.4; CE15381; WBGene00023497; WP:CE15381; XQ349 WormBase description: LIN-15B protein
                                              
Member of lists (Publications lists):
                                              ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated