Roy et al 2002 S3 muscle genes, 30 genes

Gene list file name:Roy2002.S3_34musclegenes.txt
Type of gene identifier:MA primer pair (sjj)
Description:Roy et al 2002 Supplement3: muscle genes  
Organism:Caenorhabditis elegans (nematode)
Gene list type:Experimental

Gene name             Source Gene ID          Annotation                                                  Date       Added by    

C05B5.7 C05B5.7 P W All gene names: rgs-1; C05B5.7; 3L104; CE27794; NM_066820; WBGene00004344; WP:CE27794 WormBase description: rgs-1 encodes a regulator of G protein signaling; by homology, RGS-1 is predicted to function as a GTPase-activating protein for heterotrimeric G-protein alpha-subunits, and in vitro RGS-1 can stimulate the GTPase activity of purified GOA-1; in vivo, rgs-1 appears to function redundantly with rgs-2 to regulate egg-laying behavior when animals are refed following starvation; rgs-1 is expressed in most or all neurons. WormBase CDS description: 1r20 protein (human)
                                              
Member of lists (Publications lists):
                                              Roy et al 2002  S3 muscle genes,                                  
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

C07A12.4 C07A12.4 P W All gene names: pdi-2; C07A12.4; C07A12.4a.1; C07A12.4a.2; CE03972; CE31878; NM_076377; NM_182439; WBGene00003963; WP:CE03972; WP:CE31878; XF145 WormBase description: This gene encodes a protein predicted by Eisenberg and coworkers, with 52% accuracy, to be mitochondrial.
                                              
Member of lists (Publications lists):
                                              Kwon et al 2004 T1 late-induction                                 
                                              Ethanol-response, Link et al 2003  T2 Abeta repressed,                             
                                              McCarroll et al 2004  SFig1-4 conserved w/ Drosoph,                                
                                              Reinke et al 2004, list of genes in cluster order,                                 
                                              Reinke et al 2004, list of genes in cluster C, Roy et                              
                                              al 2002  S3 muscle genes, ViswanathanM et al 2005  S2                              
                                              UPR genes, ViswanathanM et al 2005  S2 sir-2.1                                     
                                              regulated, Wang et al 2003  S3  genes pass one-way                                 
                                              ANOVA, Wang et al 2003  S4 Climbing, Wang et al 2003                               
                                              S4 genes pass two-wayANOVA P0                                                      

C40H1.6 C40H1.6 P W All gene names: C40H1.6; 3K421; CE00114; WBGene00008041; WP:CE00114
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Roy et al 2002  S3 muscle genes,                             
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated, Wang et                             
                                              al 2003  S4 Climbing, Wang et al 2003  S3  genes pass                              
                                              one-way ANOVA, Wang et al 2003  S4 genes pass                                      
                                              two-wayANOVA P0                                                                    

C47G2.1 C47G2.1 P W All gene names: cut-1; vmp-1; C47G2.1; 2L561; CE02165; NM_064009; WBGene00000851; WP:CE02165 WormBase description: cut-1 encodes a component of cuticlin, an insoluble residue of the nematode cuticle required for alae formation and radial shrinking during dauer differentiation; expressed specifically in the cuticle of dauer larvae and is secreted by the seam cells. WormBase CDS description: cuticulin
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  Non dauer genes                                 
                                              P<0.05, Reinke et al 2004, IVb male soma enriched                                  
                                              genes, Roy et al 2002  S3 muscle genes                                             

C50C3.9 C50C3.9 P W All gene names: unc-36; unc-72; C50C3.9; 3J284; CE32168; CE39702; NM_066388; WBGene00006772; WP:CE32168; WP:CE39702; eT1
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster A, Reinke et al 2004, list of genes in                                  
                                              cluster order, Roy et al 2002  S3 muscle genes,                                    
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

D2045.1 D2045.1 P W All gene names: atx-2; D2045.1; D2045.1b.1; D2045.1b.2; 3L557; CE37889; CE37967; WBGene00000231; WP:CE37889; WP:CE37967 WormBase description: atx-2 is required for early embryonic patterning; it encodes an ortholog of human ataxin-2, which when mutated leads to spinocerebellar ataxia 2 (SCA2; OMIM:183090).
                                              
Member of lists (Publications lists):
                                              Roy et al 2002  S3 muscle genes                                   

F01G12.5 F01G12.5 P W All gene names: alpha-2 (IV) collagen; clb-1; let-2; let-8; sup-20; F01G12.5; F01G12.5b.1; F01G12.5b.2; CE04334; CE04335; NM_078262; NM_078263; WBGene00002280; WP:CE04334; WP:CE04335; XQ996 WormBase description: let-2 encodes an alpha-2 type IV collagen, probably most closely equivalent to the human gene COL4A2 (OMIM:120090) on the basis of biological function; LET-2 is required for embryonic development and is a component of the basement membrane between muscle and hypodermis; LET-2 interacts with UNC-105, a mechanosensory ion channel of the degenerin ion channel superfamily that is expressed in muscle and required for normal growth, muscle contraction, and muscle organization. WormBase CDS description: alpha-2 type IV collagen
                                              
Member of lists (Publications lists):
                                              Roy et al 2002  S3 muscle genes,                                  
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

F02E9.2 F02E9.2A P W All gene names: lin-28; F02E9.2; 1I984; CE24879; CE24880; NM_059880; WBGene00003014; WP:CE24879; WP:CE24880 WormBase description: lin-28 encodes a cytoplasmic protein with a cold shock domain and retroviral-type (CCHC) zinc finger motifs; LIN-28 is required for events specific to the second larval stage, which in lin-28 mutants are skipped, and is itself subject both to negative regulation (by binding of the lin-4 stRNA to an element in the lin-28 3' UTR) and to positive regulation (by LIN-14, which negatively regulates lin-4-independent inhibition also acting on the lin-28 3' UTR). WormBase CDS description: cold shock domain
                                              
Member of lists (Publications lists):
                                              Roy et al 2002  S3 muscle genes                                   

F31E3.5 F31E3.5 P W All gene names: eft-3; eln-1; glp-3; F31E3.5; F31E3.5.1; F31E3.5.2; F31E3.5.3; F31E3.5.4; 3I58; CE01270; NM_066119; WBGene00001168; WBGene00001610; WP:CE01270 WormBase description: eft-3 encodes a translation elongation factor 1-alpha homolog that is required for embryonic viability, fertility, and germline maintenance; the EFT-3 protein sequence is encoded both by eft-3 (F31E3.5) itself but also by R03G5.1. WormBase CDS description: Elongation factor 1-alpha
                                              
Member of lists (Publications lists):
                                              Roy et al 2002  S3 muscle genes,                                  
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

F32E10.4 F32E10.4 P W All gene names: ima-3; F32E10.4; F32E10.4.1; F32E10.4.2; 4I324; CE20745; NM_068826; WBGene00002074; WP:CE20745 WormBase description: importin alpha, nuclear transport factor
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Roy et al 2002  S3 muscle genes                                           

F33A8.1 F33A8.1 P W All gene names: let-858; F33A8.1; F33A8.1.1; F33A8.1.2; 2L317; CE17753; NM_063962; WBGene00002957; WP:CE17753 WormBase description: let-858 encodes nucampholin, a highly conserved protein rich in acidic and basic residues that also shares some similarity to eukaryotic initiation factor eIF-4 gamma; LET-858 is required for early embryogenesis and tissue differentiation and is expressed ubiquitously throughout development; LET-858 localizes to nuclei where it overlaps, but is not restricted to, chromosomal regions; based upon its sequence and localization, LET-858 is likely to be involved in protein synthesis and/or RNA binding.
                                              
Member of lists (Publications lists):
                                              Link et al 2003  T2 Abeta induced,                                
                                              McCarroll et al 2004  SFig5 conserved w/ yeast,                                    
                                              McCarroll et al 2004  SFig1-4 conserved w/ Drosoph,                                
                                              Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs                             
                                              glp-4 enriched genes, Reinke et al 2004, wt herm vs wt                             
                                              male enriched gen, Roy et al 2002  S3 muscle genes                                 

F36A4.14 F36A4.14 P W All gene names: nhr-78; F36A4.14; 4F40; CE07187; NM_068129; WBGene00003668; WP:CE07187
                                              
Member of lists (Publications lists):
                                              Roy et al 2002  S3 muscle genes, Wang                             
                                              et al 2003  S3  genes pass one-way ANOVA, Wang et al                               
                                              2003  S4 Dauer Enriched, Wang et al 2003  S4 genes pass                            
                                              two-wayANOVA P0                                                                    

F40F4.2 F40F4.2 P W All gene names: lbp-2; F40F4.2; CE04532; NM_076157; WBGene00002254; WP:CE04532; XD881 WormBase description: lbp-2 encodes a homolog of the novel fatty acid binding protein, As-p18, found in the parasitic nematode Ascaris suum; As-p18 is a member of a family of small intracellular fatty acid binding proteins (iFABPs); the expression pattern of lpb-2 is consistent with it being secreted into the perienteric fluid where it may play a role in lipid transport beween the intestine and body wall; a lbp-2 promoter::gfp fusion reporter is restricted to body wall muscle cells abutting the pseudocoelom. WormBase CDS description: fatty acid-binding protein
                                              
Member of lists (Publications lists):
                                              Link et al 2003  T2 Abeta repressed,                              
                                              Reinke et al 2004, mixed sperm soma, Reinke et al 2004,                            
                                              fem3 enriched genes, Roy et al 2002  S3 muscle genes,                              
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

F40F4.4 F40F4.4 P W All gene names: lbp-3; F40F4.4; CE30130; CE39932; NM_076155; WBGene00002255; WP:CE30130; WP:CE39932; XD877
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, mixed sperm soma,                              
                                              Reinke et al 2004, fem3 enriched genes, Roy et al 2002                             
                                              S3 muscle genes, ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

F55A8.2 F55A8.2 P W All gene names: cgk-1; egl-4; odr-9; F55A8.2; F55A8.2a.1; F55A8.2a.2; 4C643; CE19897; CE19898; CE31541; CE37241; CE37242; CE37718; NM_067740; NM_067741; NM_171279; NM_171280; WBGene00001173; WP:CE19897; WP:CE19898; WP:CE31541; WP:CE37241; WP:CE37242; WP:CE37718 WormBase description: The egl-4 gene encodes a cyclic GMP-dependant protein kinase that may act through the TGF-beta signalling pathway relay sensory cues that modulate chemosensory behavior, dauer formation, foraging and egg-laying.
                                              
Member of lists (Publications lists):
                                              Roy et al 2002  S3 muscle genes,                                  
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated                                      

F59B2.13 F59B2.13 P W All gene names: SRQ-1; F59B2.13; 3K110; CE37246; WBGene00010315; WP:CE37246 WormBase description: possible G protein coupled receptor
                                              
Member of lists (Publications lists):
                                              Roy et al 2002  S3 muscle genes                                   

F59F5.6 F59F5.6 P W All gene names: syd-2; F59F5.6; CE03447; NM_077367; WBGene00006364; WP:CE03447; XL168 WormBase description: syd-2 encodes alpha-liprin, a member of the liprin family of proteins that interact with LAR (leukocyte common antigen related)-type receptor tyrosine phosphatases (RPTPs) to facilitate clustering of RPTPs to focal adhesions; SYD-2 is required for establishing normal presynaptic density, and is expressed in all neurons and muscles; SYD-2 is required cell autonomously in neurons for differentiation of presynaptic active zones, where SYD-2 is localized. WormBase CDS description: liprin-alpha
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, list of genes                             
                                              in cluster order, Reinke et al 2004, list of genes in                              
                                              cluster B, Roy et al 2002  S3 muscle genes                                         

H14N18.1 H14N18.1 P W All gene names: unc-23; vab-4; H14N18.1; H14N18.1b.1; H14N18.1b.2; 5J419; CE17973; CE33124; CE37777; NM_072906; NM_182342; WBGene00006760; WP:CE17973; WP:CE33124; WP:CE37777
                                              
Member of lists (Publications lists):
                                              GuhaThakurta et al 2002  T1 upregu on                             
                                              heat stress, McCarroll et al 2004  SFig1-4 conserved w/                            
                                              Drosoph, Murphy et al 2003  Fig2 Class1 elongate                                   
                                              lifespan, Reinke et al 2004, list of genes in cluster                              
                                              order, Reinke et al 2004, list of genes in cluster C,                              
                                              Roy et al 2002  S3 muscle genes, ViswanathanM et al                                
                                              2005  S2 sir-2.1 regulated                                                         

K08B4.1 K08B4.1 P W All gene names: lag-1; K08B4.1; 4G873; CE25048; CE28839; NM_171350; WBGene00002245; WP:CE25048; WP:CE28839 WormBase description: lag-1 encodes a transcription factor orthologous to members of the CSL (CBF1, Suppressor of Hairless, LAG-1) family that is highly conserved amongst metazoans; during development, LAG-1 functions as a downstream effector in both the lin-12- and glp-1-mediated Notch-like signaling pathways and accordingly, is required for such processes as germline induction, AC/VU lateral signaling, and embryonic development; LAG-1 can bind a consensus CSL family binding site found in multiple copies in the predicted regulatory regions of lin-12, glp-1, and lag-1, thus implicating LAG-1 as an important component of the positive feedback loop observed in the LIN-12/GLP-1 signaling pathway; LAG-1 is detected in all nuclei of the germ line except mature sperm, somatic gonad, and early embryo.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Reinke et al 2004, fem1 enriched                             
                                              genes, Reinke et al 2004, list of genes in cluster                                 
                                              order, Reinke et al 2004, mixed oogenesis soma, Reinke                             
                                              et al 2004, list of genes in cluster E, Roy et al 2002                             
                                              S3 muscle genes, ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

K10B3.7 K10B3.7 P W All gene names: gpd-3; K10B3.7; K10B3.7.1; K10B3.7.2; CE07370; NM_076133; WBGene00001685; WP:CE07370 WormBase description: gpd-3 encodes a predicted glyceraldehyde 3-phosphate dehydrogenase that affects embryonic viability; GPD-3 interacts with LIN-2 in two-hybrid assays.
                                              
Member of lists (Publications lists):
                                              Link et al 2003  T2 Abeta repressed,                              
                                              Roy et al 2002  S3 muscle genes, ViswanathanM et al                                
                                              2005  S2 sir-2.1 regulated, Wang et al 2003  S3  genes                             
                                              pass one-way ANOVA, Wang et al 2003  S4 LateList, Wang                             
                                              et al 2003  S4 genes pass two-wayANOVA P0                                          

K10B3.8 K10B3.8 P W All gene names: gpd-2; K10B3.8; CE07371; NM_076134; WBGene00001684; WP:CE07371; XD732 WormBase description: gpd-2 encodes one of four C. elegans glyceraldehyde-3-phosphate dehydrogenases (GAPDHs); by homology, GPD-2 is predicted to reversibly catalyze the oxidation and phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate during glycolysis; in C. elegans, GPD-2 and GPD-3 constitute the major GAPDH isoenzymes and are expressed at highest levels during postembryonic development, primarily in the actin-containing A and I zones of body-wall muscle; loss of gpd-2 function via RNA-mediated interference (RNAi) does not result in any abnormalities.
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig1-4                                     
                                              conserved w/ Drosoph, Murphy et al 2003  Fig2 Class1                               
                                              elongate lifespan, Roy et al 2002  S3 muscle genes,                                
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated, Wang et                             
                                              al 2003  S3  genes pass one-way ANOVA, Wang et al 2003                             
                                              S4 LateList, Wang et al 2003  S4 genes pass                                        
                                              two-wayANOVA P0                                                                    

K10D3.2 K10D3.2 P W All gene names: unc-14; K10D3.2; 1H700; CE25055; NM_059617; WBGene00006753; WP:CE25055 WormBase description: The unc-14 gene encodes an activity required for both axonogenesis and sex myoblast migration.
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster A, Reinke et al 2004, list of genes in cluster                             
                                              order, Roy et al 2002  S3 muscle genes                                             

K11D9.2 K11D9.2 P W All gene names: mca-4; sca-1; ser-1; K11D9.2; K11D9.2a.1; K11D9.2a.2; 3L902; CE18884; CE18885; NM_066984; WBGene00004736; WP:CE18884; WP:CE18885 WormBase description: The sca-1 gene encodes a sarco-endoplasmic reticulum Ca[2+] ATPase homolog that is required for development and muscle function; sca-1 is also a ortholog of human ATP2A1 (OMIM:108730), which when mutated leads to Darier-White disease (OMIM:124200). WormBase CDS description: E1-E2 ATPases
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, IVb male soma                                  
                                              enriched genes, Roy et al 2002  S3 muscle genes                                    

M7.1 M7.1 P W All gene names: let-70; ubc-2; M7.1; 4L846; CE03482; NM_069664; WBGene00002344; WP:CE03482 WormBase description: let-70 encodes a class I E2 ubiquitin conjugating enzyme; let-70 was identified in screens for essential genes and phenotypic analyses indicate that loss of let-70 activity results in embryonic and larval lethality with defects in sarcomere assembly; purified LET-70 can stimulate the self-ubiquitylation activities of CHN-1 and UFD-2, E4 ubiquitin conjugation factors and, in addition, can stimulate the CHN-1- and UFD-2-dependent multiubiquitylation of UNC-45, a myosin-directed chaperone; in this manner, LET-70 may regulate UNC-45 degradation and myosin assembly; RNA blot analyses and a let-70-lacZ reporter fusion reveal that let-70 is abundantly expressed at all stages of development, including the dauer larval stage; strong staining is observed in most somatic tissues until adult stages, when expression generally becomes restricted to the nervous system. WormBase CDS description: ubiquitin-conjugating enzyme E2-17 KD
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Roy et al 2002  S3 muscle genes, ViswanathanM                             
                                              et al 2005  S2 sir-2.1 regulated                                                   

T04C12.4 T04C12.4 P W All gene names: act-3; T04C12.4; T04C12.4.1; T04C12.4.2; T04C12.4.3; T04C12.4.4; 5L552; NM_073416; WBGene00000065; act1; act3 WormBase description: act-3 encodes an invertebrate actin, highly similar to ACT-1, ACT-2, and ACT-4, that functions in body wall muscle. WormBase CDS description: actin
                                              
Member of lists (Publications lists):
                                              Golden et al 2004, daf-2                                          
                                              differentially expressed , Reinke et al 2004, list of                              
                                              genes in cluster order, Reinke et al 2004, list of                                 
                                              genes in cluster C, Roy et al 2002  S3 muscle genes                                

T05C12.7 T05C12.7 P W All gene names: cct-1; tcp-1; T05C12.7; T05C12.7.1; T05C12.7.2; 2I477; CE02319; NM_063321; WBGene00000377; WP:CE02319 WormBase description: eukaryotic cytosolic chaperonin; affects viability and fertility, and is expressed in various muscle and neuronal cells: near the pharynx, near the anal sphincter, in the ventral nerve cord and the nerve ring; occasionally the expression is visible in hypodermal cells and in some vulval cells. WormBase CDS description: T-complex protein
                                              
Member of lists (Publications lists):
                                              McCarroll et al 2004  SFig5 conserved                             
                                              w/ yeast, McCarroll et al 2004  SFig1-4 conserved w/                               
                                              Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke                            
                                              et al 2004, wt vs glp-4 enriched genes, Reinke et al                               
                                              2004, oogenesis enriched genes, Roy et al 2002  S3                                 
                                              muscle genes, ViswanathanM et al 2005  S2 sir-2.1                                  
                                              regulated                                                                          

T28D9.2 T28D9.2 P W All gene names: CeSC35-2; rsp-5; srp-3; T28D9.2; 2G781; CE28094; CE36572; CE36573; CE36574; NM_062906; NM_062907; NM_062908; NM_062909; WBGene00004702; WP:CE28094; WP:CE36572; WP:CE36573; WP:CE36574 WormBase description: splicing factor
                                              
Member of lists (Publications lists):
                                              Reinke et al 2004, list of genes in                               
                                              cluster F, Reinke et al 2004, fem1 enriched genes,                                 
                                              Reinke et al 2004, Fig2b shared gemlines, Reinke et al                             
                                              2004, list of genes in cluster order, Reinke et al                                 
                                              2004, oogenesis enriched genes, Reinke et al 2004, wt                              
                                              vs glp-4 enriched genes, Reinke et al 2004, wt males vs                            
                                              glp4 male enriched , Reinke et al 2004, wt herm vs wt                              
                                              male enriched gen, Roy et al 2002  S3 muscle genes,                                
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated, Wang et                             
                                              al 2003  S5 genes common to feeding ANOVA, Wang et al                              
                                              2003  S3  genes pass one-way ANOVA                                                 

Y55D5A.5 Y55D5A_391.B P W All gene names: daf-2; Y55D5A.5; Y55D5A_392.A; 3E86; CE27499; NM_065249; WBGene00000898; WP:CE27499 WormBase description: daf-2 encodes a predicted receptor tyrosine kinase that is the C. elegans insulin/IGF receptor ortholog; DAF-2 activity is required for a number of processes in C. elegans, including embryonic and larval development, formation of the developmentally arrested dauer larval stage, adult longevity, reproduction, fat storage, and response to exogenous stressors such as high temperature or bacterial infection; DAF-2 signals through a conserved PI 3-kinase pathway to negatively regulate the activity of DAF-16, a Forkhead-related transcription factor, by inducing its phosphorylation and nuclear exclusion; amongst the 38 predicted insulin-like molecules in C. elegans, genetic and microarray analyses suggest that at least DAF-28, INS-1, and INS-7 are likely DAF-2 ligands; genetic mosaic and tissue-specific promoter studies indicate that daf-2 can function cell nonautonomously and within multiple cell types to influence dauer formation and adult lifespan, likely by regulating the production of secondary signals that coordinate growth and longevity throughout the animal.
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  T2 lifespan and                                 
                                              Dauer, McCarroll et al 2004  SFig1-4 conserved w/                                  
                                              Drosoph, Reinke et al 2004, intrinsic, Reinke et al                                
                                              2004, wt vs glp-4 enriched genes, Reinke et al 2004,                               
                                              list of genes in cluster order, Reinke et al 2004, list                            
                                              of genes in cluster E, Roy et al 2002  S3 muscle genes                             

ZC395.2 ZC395.2 P W All gene names: clk-1; coq-1; coq-7; ZC395.2; 3G369; CE01438; NM_065727; WBGene00000536; WP:CE01438 WormBase description: The clk-1 gene partially controls lifespan in vivo; it encodes a homolog of the yeast COQ9 protein, and is necessary for the biosynthesis of ubiquinone (UQ(9)) from demethoxyubiquinone (DMQ(9)).
                                              
Member of lists (Publications lists):
                                              Jones et al 2001  T2 lifespan and                                 
                                              Dauer, McCarroll et al 2004  SFig5 conserved w/ yeast,                             
                                              McCarroll et al 2004  SFig1-4 conserved w/ Drosoph,                                
                                              Romagnolo et al 2002  Fig3b Oxidation, Roy et al 2002                              
                                              S3 muscle genes, ViswanathanM et al 2005  S2 sir-2.1                               
                                              regulated                                                                          

ZK154.3 ZK154.3 P W All gene names: mec-7; ZK154.3; CE15257; NM_076912; WBGene00003171; WP:CE15257; XI394 WormBase description: mec-7 encodes a beta-tubulin required for touch sensitivity along the body wall, and for normal levels of locomotor activity; it is strongly expressed in six touch receptor neurons, with weak expression in FLP, PVD, and BDU cells. WormBase CDS description: beta tubulin
                                              
Member of lists (Publications lists):
                                              Roy et al 2002  S3 muscle genes,                                  
                                              ViswanathanM et al 2005  S2 sir-2.1 regulated