|Gene list file name:||Blumenthal2002_suppKS|
|Type of gene identifier:||Cosmid name|
|Description:||Operon gene pairs with confirmed spacing|
|Organism:||Caenorhabditis elegans (nematode)|
|Gene list type:||Experimental|
Gene name Source Gene ID Annotation Date Added by
B0024.10 B0024.10 P W All gene names: B0024.10; 5K796; CE05154; WBGene00007100; WP:CE05154
B0024.11 B0024.11 P W All gene names: B0024.11; 5K798; CE05155; WBGene00007101; WP:CE05155 WormBase description: Uncharacterized protein family UPF0024
B0035.11 B0035.11 P W All gene names: B0035.11; 4M94; CE05166; WBGene00007110; WP:CE05166 WormBase description: Yeast LEO1 protein like
B0035.12 B0035.12 P W All gene names: B0035.12; 4M96; CE05167; WBGene00007111; WP:CE05167 WormBase description: polyadenylate-binding protein like
B0205.6 B0205.6 P W All gene names: B0205.6; 1L315; CE30405; WBGene00015021; WP:CE30405 WormBase description: aminotransferase
B0205.7 B0205.7 P W All gene names: kin-3; B0205.7; 1L311; CE17321; NM_060410; WBGene00002191; WP:CE17321 WormBase description: kin-3 encodes an ortholog of the catalytic subunit of casein kinase II alpha, which in Drosophila and mammals is required for normal circadian rhythms, and which directly phosphorylates the Drosophila PERIOD protein (which itself regulates circadian rhythms); by analogy, KIN-3 might be expected to help regulate heterochronic functions dependent on such proteins as LIN-42. WormBase CDS description: casein kinase
B0261.1 B0261.1 P W All gene names: B0261.1; 1F835; CE29531; WBGene00015091; WP:CE29531
B0261.2 B0261.2 P W All gene names: CE-TOR; let-363; B0261.2; 1F831; CE32559; CE32560; CeTor; NM_059148; NM_059151; WBGene00002583; WP:CE32559; WP:CE32560 WormBase description: let-363 encodes, by alternative splicing, two large (>2600-residue) proteins with C-terminal similarity to phosphatidylinositol kinase (PIK); LET-363 proteins are orthologous to S. cerevisiae Tor1p and Tor2p and human FRAP1 (OMIM:601231, mammalian target of FKBP12-rapamycin); LET-363 proteins are required for progression through the L3 stage of larval development and are thought to generally stimulate translation of most or all mRNAs ('global translation'); LET-363 activity is also necessary for normal development and physiology of the intestine; LET-363 proteins are expressed ubiquitously, including a maternal contribution to the early embryo.
B0334.4 B0334.4 P W All gene names: B0334.4; 2L787; CE02936; WBGene00007144; WP:CE02936 WormBase description: Yeast hypothetical protein L8167.12 like
B0334.5 B0334.5 P W All gene names: B0334.5; 2L789; CE30122; WBGene00007145; WP:CE30122 WormBase description: phytoene synthase precursor
B0511.10 B0511.10 P W All gene names: eif-3.E; B0511.10; 1L218; CE17349; NM_060384; WBGene00001228; WP:CE17349 WormBase description: eif-3.E encodes the C. elegans ortholog of the translation initiation factor 3 subunit e (eIF3e/Int-6); by homology, EIF-3.E is predicted to be a component of three different protein complexes, the eIF3 translation initiation factor, the 26S proteasome, and the COP9 signalosome; such association suggests that EIF-3.E may serve as a regulatory factor that coordinates the translational and degradative activities of these various complexes; in C. elegans, large-scale RNAi screens indicate that eif-3.E is required for embryonic, larval, and germline development, as well as proper vulval morphogenesis.
B0511.13 B0511.13 P W All gene names: B0511.13; 1L210; CE32106; WBGene00015238; WP:CE32106
B0511.6 B0511.6 P W All gene names: B0511.6; 1L203; CE26853; WBGene00015232; WP:CE26853 WormBase description: helicase
B0511.8 B0511.8 P W All gene names: tag-264; B0511.8; 1L214; CE28880; WBGene00015234; WBGene00044321; WP:CE28880
B0511.9 B0511.9 P W All gene names: cdc-26; mat-4; tag-265; B0511.9; 1L216; CE17348; CE26854; Q8T7Y7_CAEEL; WBGene00015235; WP:CE17348; WP:CE26854
B0513.2 B0513.2 P W All gene names: B0513.2; 4O649; CE23510; WBGene00007195; WP:CE23510
B0513.3 B0513.3 P W All gene names: rpl-29; B0513.3; 4O647; CE15559; NM_070270; WBGene00004443; WP:CE15559 WormBase description: rpl-29 encodes a large ribosomal subunit L29 protein; by homology, RPL-29 is predicted to function in protein biosynthesis; in C. elegans, loss of rpl-29 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities. WormBase CDS description: 60S ribosomal protein L29
C01B10.7 C01B10.7 P W All gene names: C01B10.7; 4H403; CE06738; WBGene00015281; WP:CE06738
C01B10.8 C01B10.8 P W All gene names: C01B10.8; 4H401; CE06739; Q17539_CAEEL; WBGene00015282; WP:CE06739
C01B10.9 C01B10.9 P W All gene names: C01B10.9; 4H399; CE37181; WBGene00015283; WP:CE37181
C01F6.8 C01F6.8 P W All gene names: icl-1; C01F6.8; 4J860; CE17360; CE30069; ICln; WBGene00002046; WP:CE17360; WP:CE30069 WormBase description: The icl-1 gene encodes, through alternative splicing, two alternative forms (ICL-1A, or 'IClnN1', and ICL-1B, or 'IClnN2'), with distinct electrophysiological properties, of an anion channel homolog. WormBase CDS description: nucleotide-sensitive chloride ion channel
C01F6.9 C01F6.9 P W All gene names: C01F6.9; 4J862; CE17361; NX; WBGene00007223; WP:CE17361 WormBase description: The C01F6.9 gene resides in an operon that also contains the genes icl-1 and lpl-1.
C01G5.5 C01G5.5 P W All gene names: C01G5.5; 4H291; CE06751; WBGene00015307; WP:CE06751 WormBase description: aldehyde reductase
C01G5.6 C01G5.6 P W All gene names: C01G5.6; 4H289; CE23513; WBGene00015308; WP:CE23513
C01G8.2 C01G8.2 P W All gene names: cln-3.2; C01G8.2; 1F844; CE07802; NM_059155; WBGene00000540; WP:CE07802 WormBase description: cln-3.2 encodes a predicted transmembrane protein that comprises one of three C. elegans homologs of human CLN3 (OMIM:607042, mutations are associated with Batten disease (also known as juvenile neuronal ceroid lipofuscinosis), a recessively inherited childhood neurodegenerative lysosomal storage disease); loss of cln-3.2 activity via large-scale RNAi screens has been reported to result in either no defects or in embryonic lethality.
C01G8.3 C01G8.3 P W All gene names: dhs-1; C01G8.3; 1F848; CE07803; NM_059156; WBGene00000965; WP:CE07803 WormBase description: oxidoreductase
C01G8.4 C01G8.4 P W All gene names: dnj-4; C01G8.4; 1F850; CE26905; NM_059157; WBGene00001022; WP:CE26905 WormBase description: This gene encodes a protein containing a DnaJ ('J') domain.
C01G8.5 C01G8.5 P W All gene names: erm-1; C01G8.5; 1F852; CE07805; CE07806; NM_059158; NM_059159; P91016_CAEEL; WBGene00001333; WP:CE07805; WP:CE07806 WormBase description: The erm-1 gene encodes an ortholog of the ERM family of cytoskeletal linkers with approximately equal similarity to ezrin, radixin and moesin. WormBase CDS description: membrane protein
C02F5.3 C02F5.3 P W All gene names: C02F5.3; 3J337; CE36094; WBGene00015346; WP:CE36094 WormBase description: GTP-binding protein
C02F5.4 C02F5.4 P W All gene names: C02F5.4; 3J335; CE38771; WBGene00015347; WP:CE38771
C05C8.5 C05C8.5 P W All gene names: C05C8.5; 5H714; CE07923; WBGene00015462; WP:CE07923
C05C8.6 C05C8.6 P W All gene names: C05C8.6; 5H716; CE07924; O16313_CAEEL; WBGene00015463; WP:CE07924
C05D2.10 C05D2.10 P W All gene names: C05D2.10; 3G688; CE26861; CE29560; WBGene00015470; WP:CE26861; WP:CE29560
C05D2.6 C05D2.6 P W All gene names: C05D2.6; 3G690; CE32115; CE38996; WBGene00015468; WP:CE32115; WP:CE38996 WormBase description: C05D2.6 encodes an unfamiliar protein, with no known non-nematode homologs, that specifically binds GOA-1 in yeast two-hybrid assays; C05D2.6 is expressed in several head and tail neurons, pharyngeal muscle, intestine, distal tip cell of the gonad, with weak expression in the ventral nerve cord; C05D2.6 is required for fertility in RNAi assays, with a phenotype of either sterile progeny or reduced brood size for C05D2.6(RNAi) in an rrf-3 mutant background.
C06A1.5 C06A1.5 P W All gene names: C06A1.5; 2K871; CE02117; WBGene00007355; WP:CE02117 WormBase description: DNA directed RNA polymerase
C06G3.10 C06G3.10 P W All gene names: cgo-2; cogc-2; C06G3.10; 4H802; CE28817; CELDLC; COG2_CAEEL; NM_068691; WBGene00000585; WP:CE28817; cog2 WormBase description: cogc-2 encodes an ortholog of mammalian COG-2, a subunit of lobe A of the conserved oligomeric Golgi complex (COGC); COGC-2 is required for normal gonadal distal tip cell migration, a process that also requires seven other orthologs of COGC subunits; like other lobe A subunits in both C. elegans and S. cerevisiae, COGC-2 is strongly required for normal function, while lobe B subunits are only partially required in either worms or yeast.
C06G3.9 C06G3.9 P W All gene names: C06G3.9; 4H798; CE07985; WBGene00015555; WP:CE07985
C06H2.1 C06H2.1 P W All gene names: atp-5; phi-39; C06H2.1; 5L602; CE15602; WBGene00007385; WP:CE15602 WormBase description: ATP synthase D chain
C07A9.2 C07A9.2 P W All gene names: C07A9.2; 3J784; 3K784; CE00499; WBGene00007400; WP:CE00499 WormBase description: G10 protein
C07A9.7 C07A9.7 P W All gene names: set-3; C07A9.7; 3K782; CE00498; CE31769; WBGene00007403; WP:CE00498; WP:CE31769
C08B11.5 C08B11.5 P W All gene names: sap-49; C08B11.5; 2I326; CE36374; WBGene00004723; WP:CE36374 WormBase description: Poly(A) RNA binding protein
C08B11.6 C08B11.6 P W All gene names: C08B11.6; CE30856; WBGene00007434; WP:CE30856 WormBase description: actin
C08B11.9 C08B11.9 P W All gene names: C08B11.9; CE01479; WBGene00007436; WP:CE01479; YP89_CAEEL
C14A4.1 C14A4.1 P W All gene names: tag-242; C14A4.1; CE02138; DOHH_CAEEL; WBGene00007555; WP:CE02138
C14A4.14 C14A4.14 P W All gene names: C14A4.14; 2K875; CE24801; WBGene00007564; WP:CE24801
C14A4.2 C14A4.2 P W All gene names: dap-3; C14A4.2; 2K873; CE24802; NM_063879; WBGene00000933; WP:CE24802 WormBase description: dap-3 is an ortholog of mammalian death-associated protein 3 (DAP3), a mitochondrial ribosomal protein that promotes apoptosis.
C14A4.3 C14A4.3 P W All gene names: C14A4.3; CE32796; NM_063881; WBGene00007556; WP:CE32796
C14A4.4 C14A4.4 P W All gene names: crn-3; C14A4.4; 2K881; CE02145; CE32797; NM_063882; NM_182164; WBGene00000796; WP:CE02145; WP:CE32797 WormBase description: crn-3 encodes a cell death-related nuclease, homologous to the 100 kDa polymyositis/scleroderma autoantigen (PM/Scl-100), that is required for normal levels of DNA degradation during apoptosis; PM/Scl-100 is a ribonuclease component of the multiexonuclease exosome complex, which processes or degrades several types of RNAs in yeast; crn-3(RNAi) animals show retarded growth and a low penetrance of embryonic lethality; CRN-3 promotes both DNA degradation and cell corpse engulfment, in a partially redundant pathway that includes CRN-2 but is parallel to CPS-6; CRN-3 is predicted to be mitochondrial.
C14A4.5 C14A4.5 P W All gene names: crn-5; C14A4.5; 2K883; CE02146; NM_063883; WBGene00000798; WP:CE02146 WormBase description: Prokaryotic ribonuclease PH
C14B1.1 C14B1.1 P W All gene names: pdi-1; C14B1.1; 3E790; CE00897; NM_065345; WBGene00003962; WP:CE00897 WormBase description: protein disulfide isomerase
C14B1.10 C14B1.10 P W All gene names: C14B1.10; 3E801; CE28888; WBGene00007581; WP:CE28888
C14B1.4 C14B1.4 P W All gene names: tag-125; C14B1.4; 3E795; CE00901; WBGene00006474; WBGene00007575; WP:CE00901 WormBase description: tag-125/C14B1.4 encodes an ortholog of the histone methyltransferase subunit WDR5 (OMIM:609012) that antagonizes SynMuv transcriptional repressors. WormBase CDS description: guanine nucleotide binding protein
C14B1.5 C14B1.5 P W All gene names: C14B1.5; 3E797; CE17401; WBGene00007576; WP:CE17401 WormBase description: C14B1.5 encodes an ortholog of S. cerevisiae YIL103 and human DPH2L1/OVCA1 (OMIM:603527, deleted or downregulated in ovarian tumors); C14B1.5 is paralogous to S. cerevisiae DPH2/YKL191W, a protein component of diphtamide synthesis; C14B1.5 has no obvious function in mass RNAi assays. WormBase CDS description: diptheria toxin resistance protein
C14B1.6 C14B1.6 P W All gene names: C14B1.6; 3E807; CE31415; WBGene00007577; WP:CE31415
C15B12.6 C15B12.6 P W All gene names: C15B12.6; CE37610; Q18008_CAEEL; WBGene00015787; WP:CE37610; XH110
C15B12.7 C15B12.7 P W All gene names: cdf-1; C15B12.7; CE27065; CE29581; NM_076694; NM_076695; WBGene00000393; WP:CE27065; WP:CE29581; XH114 WormBase description: a cation diffusion facilitator protein, affects vulva development, genetically interacts with let-60/ras signaling pathway; and is expressed in the vulval muscles, the intestinal cells, and in the vulval precursor cells.
C16C10.6 C16C10.6 P W All gene names: C16C10.6; 3F258; CE01497; WBGene00007627; WP:CE01497
C16C10.7 C16C10.7 P W All gene names: rnf-5; C16C10.7; 3F254; CE01498; NM_065429; RNF5_CAEEL; WBGene00004381; WP:CE01498 WormBase description: This gene encodes a homolog of mammalian RNF5, a C3HC4 (RING-finger) zinc-finger protein. WormBase CDS description: Zinc finger, C3HC4 type (RING finger)
C16C10.8 C16C10.8 P W All gene names: C16C10.8; 3F252; CE01499; WBGene00007628; WP:CE01499 WormBase description: cell growth regulating protein
C16C2.3 C16C2.3 P W All gene names: ocrl-1; C16C2.3; 1K292; CE17405; NM_060183; WBGene00007620; WP:CE17405 WormBase description: The C16C2.3 gene encodes an inositol-1,4,5-triphosphate 5-phosphatase homolog that is homologous to human OCRL. WormBase CDS description: inositol-1,4,5-triphosphate 5-phosphatase
C16C2.4 C16C2.4 P W All gene names: C16C2.4; 1K290; CE15621; WBGene00007621; WP:CE15621
C18A3.1 C18A3.1 P W All gene names: C18A3.1; 2G11; CE01793; WBGene00015939; WP:CE01793
C18A3.2 C18A3.2 P W All gene names: C18A3.2; 2G9; CE27707; WBGene00015940; WP:CE27707
C18A3.3 C18A3.3 P W All gene names: C18A3.3; 2G7; CE28890; WBGene00015941; WP:CE28890
C23H3.3 C23H3.3 P W All gene names: C23H3.3; 2A349; CE08322; P91080_CAEEL; WBGene00016019; WP:CE08322
C23H3.4 C23H3.4 P W All gene names: sptl-1; C23H3.4; 2A347; CE08323; CE37749; WBGene00016020; WP:CE08323; WP:CE37749 WormBase description: C23H3.4 encodes a putative serine palmitoyltransferase required for normal embryonic and larval developement, locomotion, and speed of growth.
C23H3.5 C23H3.5 P W All gene names: C23H3.5; 2A339; CE08324; WBGene00016021; WP:CE08324
C25H3.12 C25H3.12 P W All gene names: C25H3.12; 2F950; CE27092; WBGene00016121; WP:CE27092
C26F1.3 C26F1.3 P W All gene names: C26F1.3; 5I259; CE06877; WBGene00016148; WP:CE06877
C26F1.4 C26F1.4 P W All gene names: rps-30; C26F1.4; 5I257; CE06878; NM_072606; WBGene00004499; WP:CE06878 WormBase description: rps-30 encodes two proteins, a small ribosomal subunit S30 protein and ubiquitin, which is cleaved from the ribosomal protein posttranslationally; by homology, S30 is predicted to function in protein biosynthesis and ubiquitin in protein degradation; in C. elegans, loss of rps-30 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities. WormBase CDS description: ribosomal protein/ubiquitin-like protein
C27A12.2 C27A12.2 P W All gene names: C27A12.2; 1G621; CE08411; O01961_CAEEL; WBGene00016154; WP:CE08411 WormBase description: zinc finger protein
C27A12.3 C27A12.3 P W All gene names: tag-146; C27A12.3; 1G615; CE38999; WBGene00006492; WP:CE38999 WormBase description: zinc finger protein
C27A12.6 C27A12.6 P W All gene names: C27A12.6; 1G630; CE08415; WBGene00016156; WP:CE08415
C27A12.7 C27A12.7 P W All gene names: C27A12.7; 1G634; CE08416; CE32810; WBGene00016157; WP:CE08416; WP:CE32810
C27A12.8 C27A12.8 P W All gene names: ari-1; C27A12.8; 1G636; CE29680; NM_059348; WBGene00016158; WP:CE29680
C27A12.9 C27A12.9 P W All gene names: C27A12.9; 1G638; CE36272; WBGene00016159; WP:CE36272
C30A5.2 C30A5.2 P W All gene names: rfs-1; C30A5.2; 3J321; CE00094; NM_066398; WBGene00004342; WP:CE00094 WormBase description: rfs-1 encodes a RAD51-like protein, orthologous to mammalian RAD-51C, that is related to bacterial recA, a multifunctional enzyme involved in DNA repair, homologous recombination, and induction of the SOS response; RFS-1 has no obvious function in mass RNAi assays; however, RFS-1 can interact with RAD-51, a C. elegans RAD51 homolog involved in meiosis and DNA repair, suggesting that RFS-1 may also play a role in these processes.
C30A5.3 C30A5.3 P W All gene names: C30A5.3; 3J315; CE32154; WBGene00016238; WP:CE32154
C30C11.4 C30C11.4 P W All gene names: C30C11.4; 3J534; CE00103; WBGene00016250; WP:CE00103 WormBase description: Msi3p
C31H5.5 C31H5.5 P W All gene names: C31H5.5; 1J624; CE17485; WBGene00007856; WP:CE17485
C33D9.5 C33D9.5 P W All gene names: C33D9.5; 4J544; CE37808; WBGene00007899; WP:CE37808 WormBase description: Yeast RAD50 like protein
C33D9.6 C33D9.6 P W All gene names: C33D9.6; 4J542; CE33760; WBGene00007900; WP:CE33760
C33D9.9 C33D9.9 P W All gene names: C33D9.9; CE29589; WBGene00007902; WP:CE29589
C33F10.4 C33F10.4 P W All gene names: C33F10.4; 2F87; CE02530; CE02531; CE27103; WBGene00016353; WP:CE02530; WP:CE02531; WP:CE27103
C33H5.17 C33H5.17 P W All gene names: C33H5.17; 4I576; CE04160; WBGene00016383; WP:CE04160
C33H5.18 C33H5.18 P W All gene names: C33H5.18; CE04161; CE26907; WBGene00016384; WP:CE04161; WP:CE26907 WormBase description: C33H5.18 encodes a CDP-diglyceride synthetase ortholog required for locomotion and osmoregulation; given its biochemical function in other organisms, C33H5.18 is expected to catalyse synthesis of cytidine diphosphate-diacylglycerol (CDP-DAG), an activated precursor for anionic and zwitterionic phospholipids, and is likely to regulate phosphatidylinositol lipid signalling; one might expect loss of C33H5.18 function to be lethal, but its deficiency may be supplemented by lipids in food.
C34C12.3 C34C12.3 P W All gene names: pph-6; C34C12.3; 3E557; CE31433; WBGene00007922; WP:CE31433 WormBase description: PROTEIN PHOSPHATASE
C34C12.8 C34C12.8 P W All gene names: C34C12.8; 3E551; CE03057; WBGene00007927; WP:CE03057 WormBase description: GRPE protein
C35D10.6 C35D10.6 P W All gene names: C35D10.6; 3F949; CE01200; WBGene00016443; WP:CE01200 WormBase description: Aldose reductase
C35D10.7 C35D10.7 P W All gene names: C35D10.7; 3F947; CE32160; CE32161; WBGene00016444; WP:CE32160; WP:CE32161
C35D10.8 C35D10.8 P W All gene names: C35D10.8; 3F945; CE29702; WBGene00016445; WP:CE29702
C35D10.9 C35D10.9 P W All gene names: ced-4; C35D10.9; 3F943; CE01203; CE38154; CED4_CAEEL; WBGene00000418; WP:CE01203; WP:CE38154 WormBase description: ced-4 encodes a novel protein; along with CED-3, CED-4 is required for the initiation of programmed cell death; accordingly, genetic analyses indicate that ced-3 and ced-4 function upstream of ced-1, ced-2, and nuc-1 in the programmed cell death pathway; in yeast two-hybrid experiments, and upon coexpression in mammalian cells, CED-4 interacts with CED-9, an anti-apoptotic BCL-2 homolog; coexpression of CED-4 and CED-9 results in redistribution of CED-4 from the cytosol to organellar membranes, suggesting that CED-9 may negatively regulate CED-4 activity by sequestering CED-4 to intracellular membranes.
C37A2.6 C37A2.6 P W All gene names: C37A2.6; 1H362; CE40194; WBGene00016492; WP:CE40194
C37A2.7 C37A2.7 P W All gene names: C37A2.7; 1H366; CE30433; RLA2_CAEEL; WBGene00016493; WP:CE30433 WormBase description: ribosomal protein
C38D4.5 C38D4.5 P W All gene names: tag-325; C38D4.5; 3F891; CE00918; WBGene00008006; WP:CE00918 WormBase description: chimaerin
C38D4.9 C38D4.9 P W All gene names: C38D4.9; 3F893; CE00922; Q18511_CAEEL; WBGene00008008; WP:CE00922 WormBase description: methylase
C43E11.7 C43E11.7 P W All gene names: ndx-7; C43E11.7; 1E808; CE30504; NM_058935; WBGene00003584; WP:CE30504 WormBase description: ndx-7 encodes a NUDIX hydrolase; by sequence comparison, NDX-7 is predicted to function as a pyrophosphatase, and is most closely related to the mouse RP2 protein that has unknown substrate specificity but is regulated transcriptionally by the presence of androgens; in C. elegans, loss of ndx-7 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, consistent with the proposed nonessential roles for Nudix proteins in eliminating potentially toxic nucleotide metabolites from cells and modulating levels of metabolic intermediates by shuttling them into alternative biochemical pathways.
C43E11.8 C43E11.8 P W All gene names: exoc-7; C43E11.8; 1E812; CE08686; WBGene00016606; WP:CE08686
C43H6.2 C43H6.2 P W All gene names: C43H6.2; WBGene00016615
C43H6.3 C43H6.3 P W All gene names: C43H6.3; CE06954; WBGene00016616; WP:CE06954; XD27
C43H6.4 C43H6.4 P W All gene names: C43H6.4; CE33917; WBGene00016617; WP:CE33917; XD25
C43H8.1 C43H8.1 P W All gene names: C43H8.1; 1L201; CE19377; WBGene00016621; WP:CE19377
C43H8.2 C43H8.2 P W All gene names: C43H8.2; 1L199; CE19378; WBGene00016622; WP:CE19378
C47G2.5 C47G2.5 P W All gene names: C47G2.5; 2L591; CE38162; Q18696_CAEEL; WBGene00008166; WP:CE38162
C48B4.6 C48B4.6 P W All gene names: C48B4.6; 3K646; CE00482; WBGene00008169; WP:CE00482
C48B4.7 C48B4.7 P W All gene names: C48B4.7; 3K648; CE00483; WBGene00008170; WP:CE00483
C48B6.2 C48B6.2 P W All gene names: C48B6.2; 1H493; CE08804; WBGene00016740; WP:CE08804 WormBase description: ribosomal protein
C48B6.3 C48B6.3 P W All gene names: C48B6.3; 1H491; CE08805; WBGene00016741; WP:CE08805
C49H3.4 C49H3.4 P W All gene names: C49H3.4; 4I681; CE34766; WBGene00016791; WP:CE34766
C49H3.5 C49H3.5 P W All gene names: ntl-4; C49H3.5; 4I679; CE27872; CE30505; NM_171388; NM_171389; Q9GYQ9_CAEEL; WBGene00003827; WP:CE27872; WP:CE30505 WormBase description: ntl-4 encodes two proteins by alternative splicing, one of which (NTL-4A) has an N-terminal RING finger and a RNA recognition motif ('RRM', 'RBD', or 'RNP'), and both of which have glutamine/asparagine-rich domains.
C50C3.7 C50C3.7 P W All gene names: C50C3.7; 3J250; CE00123; WBGene00016802; WP:CE00123 WormBase description: Inositol polyphosphate-5-phosphatase
C50C3.8 C50C3.8 P W All gene names: bath-42; C50C3.8; 3J252; BAT42_CAEEL; CE00124; WBGene00016803; WP:CE00124 WormBase description: The C50C3.8 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis.
C50F4.11 C50F4.11 P W All gene names: mdf-1; C50F4.11; 5K20; CE28212; NM_073061; WBGene00003160; WP:CE28212 WormBase description: mdf-1 encodes a coiled-coil domain-containing protein that is orthologous to the Saccharomyces cerevisiae mitotic spindle checkpoint protein Mad1p; consistent with a role as a checkpoint protein, MDF-1 is required in C. elegans for mitotic genome stability and hence, long-term survival and fertility; in vitro, MDF-1 interacts with MDF-2, the C. elegans Mad2p ortholog.
C50F4.12 C50F4.12 P W All gene names: C50F4.12; 5K16; CE05476; WBGene00008236; WP:CE05476
C50F4.13 C50F4.13 P W All gene names: his-35; C50F4.13; 5K22; CE05477; NM_073062; WBGene00001909; WP:CE05477 WormBase description: his-35 encodes an H2A histone. WormBase CDS description: histone H2A
C50F4.16 C50F4.16 P W All gene names: C50F4.16; 5K18; CE28213; WBGene00008238; WP:CE28213 WormBase description: The C50F4.16 gene encodes a NUDIX hydrolase.
C52E12.3 C52E12.3 P W All gene names: sqv-7; C52E12.3; 2H302; CE04263; NM_063035; WBGene00005025; WP:CE04263 WormBase description: The sqv-7 gene encodes a nucleotide-sugar transporter of the Golgi membrane, that is required for cytokinesis of one-cell embryos and for vulval morphogenesis; SQV-7 promotes glycosaminoglycan biosynthesis by translocating UDP-glucuronic acid, UDP-N-acetylgalactosamine, and UDP-galactose into the lumen of the Golgi apparatus; SQV-7 is biochemically active when transgenically expressed in yeast or mammalian Golgi membranes; the common requirement for SQV-7 in both cytokinesis and morphogenesis may be to promote filling an extracellular space with hygroscopic proteoglycans (either in the eggshell, or underneath the L4 cuticle), which in turn may cause the space to fill with fluid.
C52E12.4 C52E12.4 P W All gene names: C52E12.4; 2H304; CE31684; WBGene00016889; WP:CE31684
C54G4.9 C54G4.9 P W All gene names: C54G4.9; 1I602; CE05515; WBGene00008318; WP:CE05515
C55B7.8 C55B7.8 P W All gene names: Ce-dbr1; dbr-1; C55B7.8; 1H68; CE30437; DBR1_CAEEL; NM_059467; WBGene00000937; WP:CE30437 WormBase description: dbr-1 encodes a homolog of the RNA lariat-debranching enzyme; DBR-1 is predicted to function in RNA processing by hydrolyzing the 2'-5' phosphodiester bond at the branchpoint of excised lariat intron RNA, thus converting the introns into linear molecules that can subsequently be degraded by exonucleases; in C. elegans, DBR-1 activity is required for embryonic and germline development, as well as for normal rates of postembryonic growth; overexpression of C. elegans DBR-1 in Saccharomyces cerevisiae can complement the RNA processing defects of a dbr1 null mutant strain, restoring debranching activity and intron degradation to near wild-type levels. WormBase CDS description: lariat debranching enzyme
C55B7.9 C55B7.9 P W All gene names: mdt-18; C55B7.9; 1H70; CE09020; NM_059468; Q966M5_CAEEL; WBGene00007018; WP:CE09020
C56C10.10 C56C10.10 P W All gene names: C56C10.10; 2G884; CE02564; WBGene00016966; WP:CE02564 WormBase description: TPR domain
C56C10.11 C56C10.11 P W All gene names: C56C10.11; 2G890; CE28900; WBGene00016967; WP:CE28900 WormBase description: DNAJ protein
C56C10.13 C56C10.13 P W All gene names: dnj-8; C56C10.13; 2G886; CE28901; CE39709; NM_062939; WBGene00001026; WP:CE28901; WP:CE39709 WormBase description: This gene encodes a protein containing a DnaJ ('J') domain.
C56C10.7 C56C10.7 P W All gene names: C56C10.7; 2G876; CE29739; CE29740; Q95QQ3_CAEEL; WBGene00016964; WP:CE29739; WP:CE29740
C56C10.8 C56C10.8 P W All gene names: icd-1; C56C10.8; 2G878; BTF3_CAEEL; CE02573; NM_062935; WBGene00002045; WP:CE02573 WormBase description: Transcription factor BTF3 (human)
C56C10.9 C56C10.9 P W All gene names: C56C10.9; 2G880; CE02574; Q18887_CAEEL; WBGene00016965; WP:CE02574
CD4.2 CD4.2 P W All gene names: crn-2; CD4.2; 5G75; CE16950; NM_072075; WBGene00000795; WP:CE16950 WormBase description: crn-2 encodes a cell death-related nuclease, homologous to the magnesium-dependant TatD nuclease of E. coli; CRN-2 is required for normal levels of DNA degradation during apoptosis; crn-2(RNAi) 1.5-fold stage embryos display TUNEL labelling of nuclei that is five-fold higher than that seen in untreated N2 animals; CRN-2 promotes both DNA degradation and cell corpse engulfment, in a partially redundant pathway that includes CRN-3 but is parallel to CPS-6; CRN-2 is predicted to be mitochondrial.
CD4.3 CD4.3 P W All gene names: CD4.3; 5G73; CE16951; WBGene00016989; WP:CE16951
CD4.4 CD4.4 P W All gene names: CD4.4; 5G71; CE16952; WBGene00016990; WP:CE16952
D1007.4 D1007.4 P W All gene names: D1007.4; 1F148; CE09039; WBGene00017002; WP:CE09039
D1007.5 D1007.5 P W All gene names: D1007.5; 1F150; CE29034; CE33577; WBGene00017003; WP:CE29034; WP:CE33577
D1007.6 D1007.6 P W All gene names: rps-10; D1007.6; 1F152; CE09041; NM_058997; O01869_CAEEL; WBGene00004479; WP:CE09041 WormBase description: rps-10 encodes a small ribosomal subunit S10 protein. WormBase CDS description: 40S ribosomal protein S10
D1054.13 D1054.13 P W All gene names: secs-1; D1054.13; 5L284; CE05531; UGTAP_CAEEL; WBGene00008379; WP:CE05531
D1054.14 D1054.14 P W All gene names: D1054.14; 5L286; CE05532; WBGene00008380; WP:CE05532
D1054.15 D1054.15 P W All gene names: phi-13; tag-135; D1054.15; 5L288; CE05533; WBGene00006481; WP:CE05533 WormBase description: beta transducin like protein
D1054.2 D1054.2 P W All gene names: pas-2; tag-166; D1054.2; 5L251; CE05521; NM_073349; WBGene00003923; WP:CE05521 WormBase description: pas-2 encodes a proteasome subunit with highest similarity to vertebrate proteasome alpha 2 subunits. WormBase CDS description: proteasome component C3
D1054.3 D1054.3 P W All gene names: D1054.3; 5L253; CE05522; WBGene00008371; WP:CE05522
D2013.5 D2013.5 P W All gene names: eat-3; mgm-1; D2013.5; 2J619; CE32846; NM_063585; WBGene00001134; WP:CE32846 WormBase description: The eat-3 gene encodes a mitochondrial dynamin-related protein, closely related to bacterial dynamin-like proteins, that is orthologous to human OPA1 (OMIM:203740, mutated in autosomal dominant optic atrophy); EAT-3 is localized to the mitochondrial matrix and may play a role in regulating inner mitochondrial membrane morphology; EAT-3 is expressed in body wall muscle, intestine, and neurons, all tissues with high metabolic rates. WormBase CDS description: GTP-binding protein
D2013.6 D2013.6 P W All gene names: D2013.6; 2J621; CE00931; Q18966_CAEEL; WBGene00008404; WP:CE00931
D2013.7 D2013.7 P W All gene names: eif-3.F; D2013.7; 2J623; CE00932; NM_063587; WBGene00001229; WP:CE00932 WormBase description: M0V-34 protein
D2013.8 D2013.8 P W All gene names: scp-1; D2013.8; 2J627; CE32616; CE37819; WBGene00004744; WP:CE32616; WP:CE37819 WormBase description: scp-1 encodes PTC-related protein that contains a sterol-sensing domain related to human Sterol regulatory element binding protein (SREBP) cleavage activating protein.
D2013.9 D2013.9 P W All gene names: set-7; D2013.9; 2J631; CE01535; WBGene00008405; WP:CE01535
D2030.3 D2030.3 P W All gene names: D2030.3; 1I154; CE09080; WBGene00008413; WP:CE09080
D2030.4 D2030.4 P W All gene names: D2030.4; 1I156; CE09081; WBGene00008414; WP:CE09081 WormBase description: D2030.4 encodes the C. elegans ortholog of the NDUFB7/B18 subunit of the mitochondrial NADH dehydrogenase (ubiquinone) complex (complex I). WormBase CDS description: NADH:CoQ oxidoreductase subunit B18
D2096.7 D2096.7 P W All gene names: D2096.7; 4J142; CE33611; CE39238; WBGene00017074; WP:CE33611; WP:CE39238
D2096.8 D2096.8 P W All gene names: D2096.8; 4J144; CE04306; WBGene00017075; WP:CE04306
E02H1.1 E02H1.1 P W All gene names: E02H1.1; 2J880; CE30642; WBGene00008455; WP:CE30642 WormBase description: rRNA methyltransferase
E02H1.2 E02H1.2 P W All gene names: E02H1.2; 2J878; CE01537; WBGene00008456; WP:CE01537 WormBase description: GTP binding protein
F07H5.10 F07H5.10 P W All gene names: F07H5.10; 2J98; CE28906; WBGene00008561; WP:CE28906
F09E5.1 F09E5.1 P W All gene names: pkc-3; F09E5.1; 2F673; CE02604; KPC3_CAEEL; NM_062610; WBGene00004034; WP:CE02604 WormBase description: Protein kinase C
F09E5.2 F09E5.2 P W All gene names: F09E5.2; 2F667; CE32364; WBGene00017282; WP:CE32364 WormBase description: AHPC/TSA protein
F09E5.3 F09E5.3 P W All gene names: F09E5.3; 2F665; CE02610; WBGene00017283; WP:CE02610 WormBase description: Deoxyribose-phosphate aldolase
F09E5.7 F09E5.7 P W All gene names: F09E5.7; 2F643; CE02614; Q19257_CAEEL; WBGene00017285; WP:CE02614
F09E5.8 F09E5.8 P W All gene names: F09E5.8; 2F641; CE02615; WBGene00017286; WP:CE02615
F10B5.1 F10B5.1 P W All gene names: rpl-10; F10B5.1; 2I435; CE01543; NM_063306; WBGene00004421; WP:CE01543 WormBase description: rpl-10 encodes a large ribosomal subunit L10 protein required in mass RNAi assays for embryonic viability, fertility, normally rapid growth, and normal body coloration; the rpl-10 transcription unit has a nonsense transcript that is up-regulated in vivo by smg[-] mutations, indicating that rpl-10 is a natural substrate for SMG-mediated nonsense suppresssion; several other natural mRNA substrates of SMG suppression (e.g., rpl-3, rpl-7, rpl-12) have protein products that are involved in translation. WormBase CDS description: ribosomal protein L10 (QM protein)
F10B5.2 F10B5.2 P W All gene names: F10B5.2; 2I437; CE01544; WBGene00008639; WP:CE01544; YQQ2_CAEEL
F10C2.4 F10C2.4 P W All gene names: F10C2.4; 5M525; CE09308; WBGene00008645; WP:CE09308 WormBase description: F10C2.4 encodes a homolog of the DNA polymerase delta complex subunit A that is required in embryos for the normal timing of embryonic cell divisions (much as DIV-1 is) and, also, for normal chromosome segregation (probably because of defective DNA replication). WormBase CDS description: DNA polymerase family B
F10C2.5 F10C2.5 P W All gene names: F10C2.5; CE09309; NM_073617; WBGene00008646; WP:CE09309 WormBase description: mannosyl-oligosaccharide alpha-1,2-mannosidase
F10C2.6 F10C2.6 P W All gene names: drs-2; F10C2.6; 5M531; CE31906; NM_073618; WBGene00001095; WP:CE31906 WormBase description: drs-2 encodes a putative aspartyl-tRNA synthetase. WormBase CDS description: aspartyl-tRNA synthetase
F11A10.4 F11A10.4 P W All gene names: F11A10.4; 4M869; CE17656; WBGene00008685; WP:CE17656
F11A10.5 F11A10.5 P W All gene names: F11A10.5; 4M859; CE03185; WBGene00008686; WP:CE03185
F16D3.2 F16D3.2 P W All gene names: rsd-6; F16D3.2; 1I936; CE32384; NM_059868; WBGene00004684; WP:CE32384
F16D3.4 F16D3.4 P W All gene names: F16D3.4; 1I940; CE09437; WBGene00008887; WP:CE09437 WormBase description: F16D3.4 encodes an ortholog of human TUBULIN-SPECIFIC CHAPERONE D (TBCD; OMIM:604649), also known as tubulin-folding cofactor D; F16D3.4 may be a ligand and effector of the ARL2 ortholog EVL-20.
F18A1.2 F18A1.2 P W All gene names: lin-26; F18A1.2; 2H973; CE27972; WBGene00003012; WP:CE27972 WormBase description: lin-26 encodes a zinc-finger protein that shares a unique C2H2 motif together with LIR-1, LIR-2, and LIR-3; during development, lin-26 activity is required for proper differentiation of non-neuronal ectodermal cells and the somatic gonad epithelium; LIN-26 is expressed in many different cell types including the rectal rep, somatic gonad, glial, and hypodermal cells; ectopic LIN-26 expression during embryogenesis induces epithelial-like cell fates suggesting that LIN-26 is sufficient for epithelial differentiation. WormBase CDS description: transcription factor
F18A1.3 F18A1.3 P W All gene names: lir-1; F18A1.3; CE27973; CE27974; CE32627; CE37001; CE39919; Q9Y051_CAEEL; WBGene00003044; WP:CE27973; WP:CE27974; WP:CE32627; WP:CE37001; WP:CE39919 WormBase description: lir-1 encodes a LIN-26-like zinc-finger protein that shares a unique C2H2 motif together with LIR-2, LIR-3, and LIN-26; lir-1 is part of two distinct operons: it is the downstream gene in an operon with lir-2 and the upstream gene in a second, overlapping operon with lin-26; the precise role of lir-1 in C. elegans development and/or behavior is not yet known as neither loss nor gain of lir-1 function appears to result in clear abnormalities and RNAi experiments targeting lir-1 result in embryonic and larval lethality due to loss of lin-26 expression; lir-1 transcripts appear ubiquitous in early embryos, disappear, and then re-appear in later embryonic hypodermal and support cells; during larval development, a lir-1::lacZ fusion that should reflect expression of all transcripts is seen in nearly all cells with the exception of germ cells and post-L1 intestinal cells.
F18A1.4 F18A1.4 P W All gene names: lir-2; F18A1.4; 2H961; CE27975; CE27976; WBGene00003045; WP:CE27975; WP:CE27976 WormBase description: lir-2 encodes a LIN-26-like zinc-finger protein that shares a unique C2H2 motif together with LIR-1, LIR-3, and LIN-26; lir-2 is the upstream gene in an operon with lir-1 which is, in turn, the upstream gene in a second, overlapping operon with lin-26; as loss of lir-2 function via RNAi results in no obvious abnormalities, the precise role of lir-2 in C. elegans development and/or behavior is not yet known; lir-2 transcripts are ubiquitous in early embryos (2-200-cell stages).
F20C5.6 F20C5.6 P W All gene names: F20C5.6; 4J536; CE03243; Q18379_CAEEL; WBGene00008971; WP:CE03243 WormBase description: spectrin
F21C3.4 F21C3.4 P W All gene names: mut-8; rde-2; F21C3.4; 1H858; CE37005; CE38174; NM_059656; Q19672_CAEEL; WBGene00004324; WBGene00009003; WP:CE37005; WP:CE38174 WormBase description: rde-2 encodes a novel protein that is conserved in at least two other Caenorhabditis species; rde-2 is required for the functional silencing of chromosomal loci by transgenes (cosuppression) and promotes the effects of RNAi in a step after the formation of a heritable interfering agent, also affects X-chromosome nondisjunction and transposon activation; functions downstream of rde-1 in the RNAi pathway most effective against germline, but not somatically expressed, genes; RDE-2 is present predominantly in the cytosol, in complexes with MUT-7, a predicted exoribonuclease also required for RNA interference.
F21C3.5 F21C3.5 P W All gene names: pfd-6; F21C3.5; 1H860; CE05680; WBGene00009004; WP:CE05680 WormBase description: Mouse KE2 protein like
F21D5.6 F21D5.6 P W All gene names: F21D5.6; 4J506; CE03249; WBGene00009011; WP:CE03249
F21D5.7 F21D5.7 P W All gene names: F21D5.7; 4J508; CE09524; WBGene00009012; WP:CE09524 WormBase description: signal recognition particle protein (SRP54)
F22B5.10 F22B5.10 P W All gene names: F22B5.10; 2I757; CE02196; WBGene00009045; WP:CE02196
F22B5.7 F22B5.7 P W All gene names: zyg-9; F22B5.7; F22B5.8; 2I753; CE20707; NM_063383; O61442_CAEEL; WBGene00006994; WP:CE20707 WormBase description: zyg-9 encodes a predicted microtubule-association protein (MAP) of the XMAP215 family; during early embryonic development, maternal zyg-9 activity is required for microtubule-dependent processes such as meiotic and mitotic spindle organization and pronuclear migration; further, zyg-9 is essential for formation of long astral microtubules; ZYG-9 is required for centrosomal localization of TAC-1, the sole C. elegans TACC family member, with which it interacts, and mutually stabilizes, in vivo; in early embryos, ZYG-9 localizes to the meiotic spindle and spindle poles, as well as to mitotic centrosomes; during metaphase and anaphase ZYG-9 localizes to the central spindle region, and during interphase ZYG-9 is cytoplasmic; proper localization of ZYG-9 to the meiotic spindle is dependent upon wild-type activity of MEI-1, an ATPase essential for meiotic spindle formation, while proper localization of ZYG-9 to centrosomes is dependent, at least in part, upon TAC-1. WormBase CDS description: elongation factor
F22B5.9 F22B5.9 P W All gene names: frs-2; F22B5.9; 2I755; CE20708; WBGene00001498; WP:CE20708 WormBase description: phenylalanyl-tRNA synthetase
F23F1.1 F23F1.1 P W All gene names: F23F1.1; CE27996; WBGene00017742; WP:CE27996
F23H11.5 F23H11.5 P W All gene names: F23H11.5; 3B528; CE09613; WBGene00000263; WP:CE09613 WormBase description: The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway.
F23H11.9 F23H11.9 P W All gene names: F23H11.9; 3B526; CE09617; CE37763; WBGene00017763; WP:CE09617; WP:CE37763
F25B5.5 F25B5.5 P W All gene names: F25B5.5; 3H34; CE01922; CK5P1_CAEEL; WBGene00017776; WP:CE01922
F25B5.6 F25B5.6 P W All gene names: F25B5.6; 3H36; CE01923; CE29283; CE37764; WBGene00017777; WP:CE01923; WP:CE29283; WP:CE37764 WormBase description: tetrahydrofolylpolyglutamate synthase
F25G6.8 F25G6.8 P W All gene names: F25G6.8; 5J44; CE09644; WBGene00017799; WP:CE09644
F25G6.9 F25G6.9 P W All gene names: F25G6.9; 5J46; CE32879; WBGene00017800; WP:CE32879
F25H2.10 F25H2.10 P W All gene names: rpa-0; F25H2.10; 1L145; CE09655; NM_060365; RLA0_CAEEL; WBGene00004408; WP:CE09655 WormBase description: rpa-0 encodes an acidic ribosomal subunit protein P0. WormBase CDS description: deoxyribonuclease
F25H2.11 F25H2.11 P W All gene names: tct-1; F25H2.11; 1L147; CE09656; NM_060366; TCTP_CAEEL; WBGene00009122; WP:CE09656 WormBase description: TCTP protein
F26A1.1 F26A1.1 P W All gene names: F26A1.1; 3F941; CE27757; WBGene00017801; WP:CE27757
F26G1.1 F26G1.1 P W All gene names: F26G1.1; 2F85; CE37362; WBGene00017837; WP:CE37362
F27C1.6 F27C1.6 P W All gene names: F27C1.6; 1F990; CE09718; P91280_CAEEL; WBGene00017855; WP:CE09718
F27C1.7 F27C1.7 P W All gene names: atp-3; F27C1.7; 1F996; CE09719; CE36139; P91283_CAEEL; WBGene00000230; WBGene00017856; WP:CE09719; WP:CE36139 WormBase description: atp-3 encodes a mitochondrial ATP synthase and is part of a regulatory system that controls and establishes rates of respiration, behavior and aging during development that persist during adulthood.
F28B3.10 F28B3.10 P W All gene names: F28B3.10; 1F518; CE28924; WBGene00017889; WP:CE28924
F28B3.6 F28B3.6 P W All gene names: F28B3.6; 1F520; CE33384; WBGene00017887; WP:CE33384
F28B3.7 F28B3.7 P W All gene names: him-1; smc-1; F28B3.7; 1F522; CE29497; CE39925; NM_059085; WBGene00001860; WP:CE29497; WP:CE39925 WormBase description: him-1 encodes a homolog of the conserved eukaryotic protein, SMC1, a member of the SMC (structural maintenance of chromosomes) superfamily that is required for embryonic viability, germline mitosis, chromosome pairing, and the segregation of mitotic chromosomes; HIM-1 can interact with SMC-3 and is required for DPY-28 localization to meiotic chromosomes; associates with the chromatin of transition-zone nuclei.
F28F8.5 F28F8.5 P W All gene names: F28F8.5; 5Q54; CE09759; WBGene00009223; WP:CE09759
F28F8.6 F28F8.6 P W All gene names: atx-3; tag-70; F28F8.6; 5Q56; ATX3_CAEEL; CE09760; NM_074472; WBGene00006446; WP:CE09760 WormBase description: tag-70/F28F8.6 encodes an ortholog of human ATAXIN-3 (OMIM:607047, mutated in Machado-Joseph disease). WormBase CDS description: Human Machedo-Joseph disease protein 1 like
F31D4.1 F31D4.1 P W All gene names: F31D4.1; 5V311; CE31921; WBGene00009289; WP:CE31921
F33D11.10 F33D11.10 P W All gene names: F33D11.10; 1G444; CE09901; WBGene00018007; WP:CE09901 WormBase description: intiation factor/helicase
F33D11.11 F33D11.11 P W All gene names: F33D11.11; 1G446; CE09902; O44782_CAEEL; WBGene00018008; WP:CE09902
F33D11.12 F33D11.12 P W All gene names: F33D11.12; CE28292; WBGene00018009; WP:CE28292
F33D11.9 F33D11.9 P W All gene names: F33D11.9; 1G434; CE30527; CE37904; WBGene00018006; WP:CE30527; WP:CE37904
F33G12.2 F33G12.2 P W All gene names: F33G12.2; 2F320; CE27149; WBGene00018014; WP:CE27149
F33G12.3 F33G12.3 P W All gene names: F33G12.3; 2F322; CE04481; WBGene00018015; WP:CE04481
F33G12.4 F33G12.4 P W All gene names: F33G12.4; 2F326; CE27150; WBGene00018016; WP:CE27150
F33G12.5 F33G12.5 P W All gene names: F33G12.5; 2F328; CE37768; Q19989_CAEEL; WBGene00018017; WP:CE37768
F35H10.5 F35H10.5 P W All gene names: F35H10.5; 4J67; CE04505; WBGene00018070; WP:CE04505
F35H10.6 F35H10.6 P W All gene names: F35H10.6; 4J65; CE38515; WBGene00018071; WP:CE38515
F35H10.7 F35H10.7 P W All gene names: F35H10.7; 4J63; CE04507; WBGene00018072; WP:CE04507
F37A4.1 F37A4.1 P W All gene names: F37A4.1; 3H813; CE00711; WBGene00018131; WP:CE00711
F37A4.2 F37A4.2 P W All gene names: F37A4.2; 3H811; CE00710; WBGene00018132; WP:CE00710
F37C12.1 F37C12.1 P W All gene names: F37C12.1; 3I277; CE00742; WBGene00018149; WP:CE00742
F37C12.13 F37C12.13 P W All gene names: F37C12.13; 3I286; CE26424; CE30780; WBGene00018154; WP:CE26424; WP:CE30780
F37C12.2 F37C12.2 P W All gene names: F37C12.2; 3I275; CE00741; WBGene00018150; WP:CE00741
F37C12.3 F37C12.3 P W All gene names: F37C12.3; 3I273; CE33082; WBGene00018151; WP:CE33082
F37C12.4 F37C12.4 P W All gene names: rpl-36; F37C12.4; 3I271; CE30781; NM_066172; RL36_CAEEL; WBGene00004450; WP:CE30781 WormBase description: rpl-36 encodes a large ribosomal subunit L36 protein; by homology, RPL-36 is predicted to function in protein biosynthesis; in C. elegans, RPL-36 activity is required for embryonic and germline development and normal postembryonic growth rates. WormBase CDS description: Ribosomal protein YL39
F39B2.1 F39B2.1 P W All gene names: F39B2.1; 1P385; CE16007; WBGene00009553; WP:CE16007 WormBase description: Zinc finger, C2H2 type (7 domains)
F39B2.2 F39B2.2 P W All gene names: mms-2; uev-1; F39B2.2; 1P383; CE16008; NM_061177; WBGene00006730; WP:CE16008 WormBase description: uev-1 encodes a ubiquitin-conjugating enzyme (UBC or E2) variant that contains the characteristic UBC motif, but lacks the critical active-site cysteine residue necessary for catalytic activity; as loss of UEV-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UEV-1 in C. elegans development and/or behavior is not yet known; UEV-1 does, however, interact with a number of proteins, such as UBC-13, that are likely involved in the response to DNA damage; thus, UEV-1 may play a role in ubiquitination and protein turnover in conjunction with DNA repair or the DNA damage checkpoint pathway.
F39H2.2 F39H2.2 P W All gene names: cyn-14; cyp-14; sig-7; F39H2.2; 1J227; CE32410; CE32411; NM_059942; NM_182005; WBGene00000890; WP:CE32410; WP:CE32411 WormBase description: cyp-14 encodes a predicted cyclophilin. WormBase CDS description: peptidylprolyl isomerase
F40G9.1 F40G9.1 P W All gene names: F40G9.1; 3A811; CE19848; WBGene00018239; WP:CE19848
F40G9.2 F40G9.2 P W All gene names: F40G9.2; 3A809; CE19849; WBGene00018240; WP:CE19849
F40G9.3 F40G9.3 P W All gene names: ubc-20; F40G9.3; 3A807; CE19850; NM_064773; WBGene00006715; WP:CE19850 WormBase description: ubiquitin conjugating enzyme
F41G3.14 F41G3.14 P W All gene names: F41G3.14; 2H33; CE28932; Q95QG7_CAEEL; WBGene00018305; WP:CE28932
F41G3.6 F41G3.6 P W All gene names: F41G3.6; 2H35; CE28933; WBGene00018302; WP:CE28933
F42A6.6 F42A6.6 P W All gene names: F42A6.6; 4E94; CE34559; WBGene00018328; WP:CE34559
F42A6.7 F42A6.7 P W All gene names: hrp-1; rbp-1; F42A6.7; 4E102; CE17059; CE29317; CE31510; CE39251; NM_067925; WBGene00001999; WP:CE17059; WP:CE29317; WP:CE31510; WP:CE39251 WormBase description: The hrp-1 gene encodes a homolog of the human DRPLA gene (OMIM:125370), which when mutated leads to dentatorubral-pallidoluysian atrophy or to Haw River syndrome (OMIM:140340).
F43G9.12 F43G9.12 P W All gene names: F43G9.12; 1J219; CE17822; WBGene00009672; WP:CE17822 WormBase description: Human GC-rich sequence DNA-binding factor (GCF) like
F43G9.13 F43G9.13 P W All gene names: F43G9.13; 1J183; CE27163; WBGene00009673; WP:CE27163
F44B9.5 F44B9.5 P W All gene names: F44B9.5; 3J104; CE24973; WBGene00018408; WP:CE24973
F44B9.6 F44B9.6 P W All gene names: lin-36; F44B9.6; 3J106; CE30992; NM_066346; WBGene00003021; WP:CE30992
F45G2.7 F45G2.7 P W All gene names: F45G2.7; 3O522; CE16050; WBGene00009733; WP:CE16050
F45G2.8 F45G2.8 P W All gene names: F45G2.8; 3O524; CE16051; WBGene00009734; WP:CE16051
F45G2.9 F45G2.9 P W All gene names: F45G2.9; 3O526; CE16052; WBGene00009735; WP:CE16052
F46B6.12 F46B6.12 P W All gene names: F46B6.12; 5K254; CE26972; WBGene00009776; WP:CE26972
F46B6.3 F46B6.3 P W All gene names: mab-14; smg-4; F46B6.3; 5K256; CE26973; CE30440; NM_171514; NM_171515; WBGene00004882; WP:CE26973; WP:CE30440
F46B6.4 F46B6.4 P W All gene names: F46B6.4; 5K258; CE05870; WBGene00009769; WP:CE05870 WormBase description: GTP-binding protein
F46B6.5 F46B6.5 P W All gene names: F46B6.5; 5K260; CE33788; CE33789; CE34023; WBGene00009770; WP:CE33788; WP:CE33789; WP:CE34023
F46B6.6 F46B6.6 P W All gene names: F46B6.6; 5K264; CE26974; WBGene00009771; WP:CE26974 WormBase description: initiation factor IF-2
F46B6.7 F46B6.7 P W All gene names: ztf-7; F46B6.7; 5K268; CE05873; WBGene00009772; WP:CE05873 WormBase description: Zinc finger, C2H2 type
F46C5.9 F46C5.9 P W All gene names: F46C5.9; 2J100; CE10584; P90814_CAEEL; WBGene00009784; WP:CE10584 WormBase description: G-protein
F48C1.5 F48C1.5 P W All gene names: F48C1.5; 1F884; CE10740; WBGene00018598; WP:CE10740
F48C1.6 F48C1.6 P W All gene names: F48C1.6; 1F886; CE10742; WBGene00018599; WP:CE10742
F52B5.2 F52B5.2 P W All gene names: F52B5.2; 1I892; CE24993; WBGene00009921; WP:CE24993 WormBase description: serine/threonine kinase (2 domains)
F52B5.3 F52B5.3 P W All gene names: F52B5.3; 1I896; CE05718; WBGene00009922; WP:CE05718 WormBase description: The F52B5.3 gene encodes a DEAH helicase orthologous to the Drosophila SpindleE protein. WormBase CDS description: helicase
F53F1.2 F53F1.2 P W All gene names: F53F1.2; 5N887; CE10934; WBGene00009980; WP:CE10934 WormBase description: aldehyde reductase
F53F1.3 F53F1.3 P W All gene names: F53F1.3; 5N889; CE10936; WBGene00009981; WP:CE10936 WormBase description: aldehyde reductase
F54C1.2 F54C1.2 P W All gene names: dom-3; F54C1.2; 1F573; CE11044; NM_059095; WBGene00001050; WP:CE11044
F54C1.3 F54C1.3 P W All gene names: mes-3; F54C1.3; 1F571; CE11046; CE36305; NM_059094; WBGene00003221; WP:CE11046; WP:CE36305 WormBase description: mes-3 encodes a novel protein with no discernible motifs; however, as a member of a Polycomb-like chromatin repressive complex with MES-2 and MES-6, MES-3 is required maternally for normal germline development and during larval development, for anteroposterior patterning; during germline development, the MES-2/MES-3/MES-6 complex is believed to be essential for maintaining repression of the X chromosome, and in transgenic animals, the complex is necessary for germline repression of repetitive transgenes; in axial patterning, the MES-2/MES-3/MES-6 complex is required in somatic tissues for maintaining homeotic gene repression, acting upstream of the Hox genes lin-39, mab-5, and egl-5, as well as the egl-5 target gene lin-32; MES-3 expression is detected in the nuclei of all cells during early embryogenesis, in some somatic cells and the germline precursors Z2 and Z3 during late embryogenesis and the L1 larval stage; in adults, MES-3 is expressed at highest levels in oocytes and germline nuclei in the proximal meiotic region with expression in the pachytene region negatively regulated by the RNA-binding protein GLD-1; MES-3 appears to be localized primarily to the nucleoplasm with some chromosomal association detectable during metaphase and early anaphase; in >24-cell-stage embryos, normal MES-3 levels and localization are dependent upon wild-type activity of MES-2 and MES-6
F54C9.5 F54C9.5 P W All gene names: rpl-5; F54C9.5; 2I861; CE02255; NM_063410; WBGene00004416; WP:CE02255 WormBase description: rpl-5 encodes a large ribosomal subunit L5 protein; by homology, RPL-5 is predicted to function in protein biosynthesis; in C. elegans RPL-5 activity is broadly required for embryonic, larval, germline, and vulval development, as well as normal body coloration, morphology, and postembryonic growth rates. WormBase CDS description: 60S ribosomal protein L5
F54C9.6 F54C9.6 P W All gene names: F54C9.6; 2I863; CE02256; CE38194; WBGene00010042; WP:CE02256; WP:CE38194 WormBase description: F54C9.6 encodes a protein orthologous to the human mitochondrial protein BCS1 (YEAST HOMOLOG)-LIKE (BCS1L; OMIM:603647); mutation of BCS1L leads to neonatal tubulopathy, encephalopathy, and liver failure, or to GRACILE syndrome. WormBase CDS description: ATP-binding protein (CDC48/PAS1/SEC18 family)
F54E12.2 F54E12.2 P W All gene names: F54E12.2; 4M98; CE11083; WBGene00010061; WP:CE11083 WormBase description: helicase
F55A3.2 F55A3.2 P W All gene names: F55A3.2; 1L373; CE17112; WBGene00018848; WP:CE17112
F55A3.3 F55A3.3 P W All gene names: phi-16; F55A3.3; 1L369; CE17113; WBGene00018849; WP:CE17113 WormBase description: transcritpion factor
F55B12.3 F55B12.3 P W All gene names: egl-41; sel-10; F55B12.3; 5O305; CE25007; CE27762; SEL10_CAEEL; WBGene00004767; WP:CE25007; WP:CE27762 WormBase description: sel-10 encodes two isoforms of an F-box and WD-repeat-containing protein that is a member of the CDC4/CUL-1 family of E2-E3 ubiquitin ligases that target cell cycle control proteins for ubiquitin-mediated degradation; SEL-10 functions as a negative regulator of the LIN-12/Notch-like signaling pathway in C. elegans and thus may contribute to cell fate decisions mediated by LIN-12; SEL-10 physically interacts with LIN-12 and with SEL-12, a C. elegans presenilin, and as such, is proposed to regulate the levels and/or activity of these proteins; SEL-10 also plays a role in sexual fate determination by regulating sexually dimorphic apoptosis of hermaphrodite- and male-specific neurons; the targets of SEL-10 in these sex-specific fate decisions are not yet known.
F55B12.4 F55B12.4 P W All gene names: F55B12.4; CE26815; WBGene00010089; WP:CE26815 WormBase description: poly(A) polymerase like
F55D10.2 F55D10.2 P W All gene names: rpl-25.1; F55D10.2; CE02777; NM_076407; WBGene00004438; WP:CE02777; XF335 WormBase description: rpl-25.1 encodes a large ribosomal subunit L23a protein. WormBase CDS description: Ribosomal protein L23
F55D10.3 F55D10.3 P W All gene names: glit-1; F55D10.3; CE04659; NM_076406; WBGene00018878; WP:CE04659; XF333 WormBase description: Esterase
F55F8.2 F55F8.2 P W All gene names: F55F8.2; 1G216; CE11190; CE33400; WBGene00018890; WP:CE11190; WP:CE33400 WormBase description: RNA helicase
F55F8.3 F55F8.3 P W All gene names: F55F8.3; 1G218; CE30542; WBGene00018891; WP:CE30542
F55F8.4 F55F8.4 P W All gene names: cir-1; tag-326; F55F8.4; 1G222; CE11194; WBGene00018892; WP:CE11194
F55F8.5 F55F8.5 P W All gene names: tag-345; F55F8.5; 1G224; CE11196; WBGene00018893; WP:CE11196
F55F8.6 F55F8.6 P W All gene names: F55F8.6; CE11198; WBGene00018894; WP:CE11198
F57B9.4 F57B9.4 P W All gene names: coq-2; F57B9.4; 3I27; CE28469; CE28470; CE32444; CE32445; CE32446; NM_066111; NM_066112; NM_181953; NM_181954; WBGene00000762; WP:CE28469; WP:CE28470; WP:CE32444; WP:CE32445; WP:CE32446 WormBase description: coq-2 encodes a putative para-hydroxybenzoate-polyprenyl transferase (UbiA prenyltransferase), orthologous to S. cerevisiae COQ2; COQ-2 is required for ubiquinone (coenzyme Q9) biosynthesis and for normally short lifespan; coq-2 mutants have slowed pharyngeal pumping, and eventually arrest as paralysed larvae before dying; coq-2(RNAi) animals have reduced levels of coenzyme Q9 and superoxide, and have abnormally long lifespans; coq-2 mutants are not rescued by dietary coenzyme Q.
F57B9.5 F57B9.5 P W All gene names: byn-1; F57B9.5; 3I25; CE25013; NM_066109; WBGene00000276; WP:CE25013 WormBase description: byn-1 encodes a homolog of mammalian BYSTIN-LIKE (BYSL; OMIM:603871).
F57B9.6 F57B9.6 P W All gene names: inf-1; F57B9.6; 3I21; CE01341; CE38524; Ce1F; CeIF; NM_066108; WBGene00002083; WP:CE01341; WP:CE38524 WormBase description: inf-1 encodes a protein with high similarity to eukaryotic initiation factor 4A.
F59A3.3 F59A3.3 P W All gene names: F59A3.3; 1G74; CE11420; RM24_CAEEL; WBGene00019076; WP:CE11420
F59A3.4 F59A3.4 P W All gene names: F59A3.4; 1G76; CE11422; WBGene00019077; WP:CE11422
F59E12.13 F59E12.13 P W All gene names: fut-3; tag-8; F59E12.13; 2F948; CE29413; NM_062705; O01906_CAEEL; WBGene00006402; WP:CE29413
H19N07.3 H19N07.3 P W All gene names: H19N07.3; 5L598; CE16184; WBGene00010407; WP:CE16184
H19N07.4 H19N07.4 P W All gene names: H19N07.4; 5L600; CE16185; WBGene00010408; WP:CE16185 WormBase description: H19N07.4 encodes an integral membrane protein with acyl-CoA:diacylglycerol o-acyltransferase activity when expressed in yeast; H19N07.4 belongs to the MBOAT protein family, whose biochemically characterized members transfer fatty acids or acetate to membrane-associated hydroxyl-bearing substrates such as cholesterol, diacylglycerol, long-chain alcohols, or alginate; MBOAT proteins include MOM-1 and its Drosophila homolog PORCUPINE, involved in Wnt signalling; H19N07.4 has no obvious function in mass RNAi assays.
H38K22.2 H38K22.2 P W All gene names: dcn-1; H38K22.2; 3F405; CE33527; CE33528; DCN1_CAEEL; NM_065465; NM_065466; WBGene00010428; WP:CE33527; WP:CE33528
H38K22.3 H38K22.3 P W All gene names: tag-131; H38K22.3; 3F409; CE18831; WBGene00006478; WP:CE18831
K02B12.5 K02B12.5 P W All gene names: K02B12.5; 1J94; CE39383; WBGene00010498; WP:CE39383 WormBase description: ankyrin motif
K02B12.7 K02B12.7 P W All gene names: K02B12.7; 1J104; CE11618; WBGene00010500; WP:CE11618 WormBase description: ADP-ribosylation factor 1-directed GTPase activating protein
K02B12.8 K02B12.8 P W All gene names: zhp-3; K02B12.8; 1J106; CE34201; NM_059910; WBGene00006976; WP:CE34201 WormBase description: zhp-3 encodes a RING finger protein that is related to the Saccharomyces cerevisiae meiotically expressed protein Zip3p; in C. elegans, ZHP-3 activity is required during meiosis for crossover recombination and chiasma formation; ZHP-3 activity is thus essential for proper chromosome segregation and normal levels of fertility; a ZHP-3::GFP fusion protein localizes along synapsed chromosomes in a manner that is dependent upon the presence of mature synaptonemal complexes.
K02F3.1 K02F3.1 P W All gene names: K02F3.1; 3B473; CE31028; WBGene00019325; WP:CE31028 WormBase description: helicase
K02F3.12 K02F3.12 P W All gene names: K02F3.12; 3B477; CE33668; CE38084; WBGene00019334; WP:CE33668; WP:CE38084
K03B4.1 K03B4.1 P W All gene names: K03B4.1; 5F169; CE28579; WBGene00019353; WP:CE28579
K03B4.2 K03B4.2 P W All gene names: K03B4.2; CE07322; NM_071861; WBGene00019354; WP:CE07322
K03B4.3 K03B4.3 P W All gene names: TAF-11; taf-10; K03B4.3; 5F167; CE07323; CE28580; NM_071859; NM_071860; WBGene00006392; WP:CE07323; WP:CE28580
K03B8.9 K03B8.9 P W All gene names: deg-3; K03B8.9; 5L894; CE06083; NM_073496; WBGene00000951; WP:CE06083 WormBase description: deg-3 encodes an alpha subunit of a nicotinic acetylcholine receptor (nAChR); originally defined by a gain-of-function mutation that results in neuronal degeneration and uncoordinated movement, DEG-3 can form heteromeric channels with a second alpha subunit, DES-2, and in vivo these channels appear to be required for chemosensation of choline; deg-3 and des-2 reside in an operon, and consistent with their role in metabolite chemosensation, are expressed in nonsynaptic regions such as the sensory endings of the IL2 chemosensory neurons; DEG-3 and DES-2 are also detected in the touch cell neurons, M1 head muscles, FLP and PVD sensory neurons, and the PVC interneuron; in subsets of these neurons, DEG-3 expression is not detectable in mec-3 or unc-86 mutant backgrounds. WormBase CDS description: nicotinic acetylcholine receptor
K04D7.1 K04D7.1 P W All gene names: rack-1; K04D7.1; 4K941; CE06090; GBLP_CAEEL; WBGene00010556; WP:CE06090 WormBase description: guanine nucleotide-binding protein
K04D7.2 K04D7.2 P W All gene names: K04D7.2; 4K943; CE28240; CE28241; MSP1_CAEEL; WBGene00010557; WP:CE28240; WP:CE28241 WormBase description: TAT binding homolog 4 like
K04G2.1 K04G2.1 P W All gene names: iftb-1; phi-17; K04G2.1; 1I604; CE16227; WBGene00010560; WP:CE16227 WormBase description: translational initiation factor 2 beta subunit
K04G7.10 K04G7.10 P W All gene names: rnp-7; K04G7.10; 3I248; CE30443; NM_066164; WBGene00004390; WP:CE30443 WormBase description: SN-RNP U1
K04G7.4 K04G7.4 P W All gene names: nuo-4; K04G7.4; 3I246; CE01361; CE31031; WBGene00019401; WP:CE01361; WP:CE31031 WormBase description: NADH dehydrogenase
K06H7.3 K06H7.3 P W All gene names: K06H7.3; 3J183; CE26941; NM_066364; WBGene00019457; WP:CE26941 WormBase description: Isopentenyl-diphosphate delta isomerase
K06H7.4 K06H7.4 P W All gene names: grp-1; K06H7.4; 3J177; CE26942; GRP1_CAEEL; NM_066363; WBGene00001743; WP:CE26942 WormBase description: sec7
K07A1.10 K07A1.10 P W All gene names: K07A1.10; 1K190; CE39387; WBGene00010616; WP:CE39387
K07A1.11 K07A1.11 P W All gene names: rba-1; K07A1.11; 1K194; CE11860; NM_060150; WBGene00004312; WP:CE11860 WormBase description: retinablastoma-binding protein RBAP46 like
K07A1.12 K07A1.12 P W All gene names: lin-53; rba-2; K07A1.12; 1K196; CE16234; NM_060151; WBGene00003036; WP:CE16234 WormBase description: chromatin assembly factor 1 P55 subunit like
K07H8.1 K07H8.1 P W All gene names: K07H8.1; 4J61; CE18021; WBGene00019503; WP:CE18021
K07H8.2 K07H8.2 P W All gene names: K07H8.2; 4J57; CE18022; CE28593; CE37721; WBGene00019504; WP:CE18022; WP:CE28593; WP:CE37721
K07H8.3 K07H8.3 P W All gene names: K07H8.3; 4J55; CE18023; WBGene00019505; WP:CE18023
K08D10.3 K08D10.3 P W All gene names: rnp-3; K08D10.3; 4E939; CE07355; NM_068104; WBGene00004386; WP:CE07355 WormBase description: U1 small nuclear ribonucleoprotein A
K08D10.4 K08D10.4 P W All gene names: rnp-2; K08D10.4; 4E937; CE28597; NM_068103; WBGene00004385; WP:CE28597 WormBase description: U1 small nuclear ribonucleoprotein A
K08F11.3 K08F11.3 P W All gene names: cif-1; K08F11.3; 4F472; CE11954; CSN7_CAEEL; WBGene00019543; WP:CE11954
K08F11.4 K08F11.4 P W All gene names: yrs-1; K08F11.4; 4F476; CE29515; CE31714; NM_171324; NM_171325; WBGene00006968; WP:CE29515; WP:CE31714 WormBase description: yrs-1 encodes a tyrosinyl tRNA synthetase predicted to be mitochondrial.
K08F11.5 K08F11.5 P W All gene names: K08F11.5; 4F478; CE11958; MIRO_CAEEL; WBGene00019544; WP:CE11958 WormBase description: RAS-related protein
K10B3.7 K10B3.7 P W All gene names: gpd-3; K10B3.7; CE07370; NM_076133; WBGene00001685; WP:CE07370 WormBase description: gpd-3 encodes a predicted glyceraldehyde 3-phosphate dehydrogenase that affects embryonic viability; GPD-3 interacts with LIN-2 in two-hybrid assays.
K10B3.8 K10B3.8 P W All gene names: gpd-2; K10B3.8; CE07371; G3P2_CAEEL; NM_076134; WBGene00001684; WP:CE07371; XD732 WormBase description: gpd-2 encodes one of four C. elegans glyceraldehyde-3-phosphate dehydrogenases (GAPDHs); by homology, GPD-2 is predicted to reversibly catalyze the oxidation and phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate during glycolysis; in C. elegans, GPD-2 and GPD-3 constitute the major GAPDH isoenzymes and are expressed at highest levels during postembryonic development, primarily in the actin-containing A and I zones of body-wall muscle; loss of gpd-2 function via RNA-mediated interference (RNAi) does not result in any abnormalities.
K10B3.9 K10B3.9 P W All gene names: mai-1; K10B3.9; CE07372; NM_076135; WBGene00003124; WP:CE07372 WormBase description: mai-1 is homologous to mitochondrial intrinsic ATPase inhibitor protein (IF(1)), which blocks reverse action (ATP hydrolysis) by F(0)F(1)-ATPase when its (normally required) proton gradient is lost; MAI-1 lacks an obvious mitochondrial import signal at its N-terminus, and is not transported to yeast mitochondria; MAI-1 may be cytosolic in vivo, regulating cytosolic ATPase(s); MAI-1 can inhibit yeast F(0)F(1)-ATPase, but this inhibition is pH-independent; MAI-1's tertiary structure is dominated by beta-strands and random loops; mai-1 exists as the upstream gene in an operon with gpd-2 and gpd-3.
K11B4.1 K11B4.1 P W All gene names: K11B4.1; 1P387; CE29597; WBGene00010766; WP:CE29597
K11B4.2 K11B4.2 P W All gene names: K11B4.2; 1P391; CE23868; WBGene00010767; WP:CE23868
K12H4.3 K12H4.3 P W All gene names: K12H4.3; 3J135; CE00268; WBGene00019678; WP:CE00268
K12H4.4 K12H4.4 P W All gene names: phi-20; K12H4.4; 3J133; CE00269; WBGene00019679; WP:CE00269 WormBase description: Signal peptidase
K12H4.5 K12H4.5 P W All gene names: K12H4.5; 3J131; CE00270; WBGene00019680; WP:CE00270
M04B2.1 M04B2.1 P W All gene names: gei-2; mep-1; M04B2.1; 4M291; CE31852; NM_069772; WBGene00003218; WP:CE31852 WormBase description: mep-1 is required for repression by the fem-3 3' UTR in vivo, and for maintenance of somatic (versus germline) differentiation; MEP-1 protein has zinc-finger domains and a glutamine/asparagine-rich domain. WormBase CDS description: zinc-finger protein
M04B2.2 M04B2.2 P W All gene names: M04B2.2; 4M293; CE32909; WBGene00010846; WP:CE32909
M05D6.2 M05D6.2 P W All gene names: M05D6.2; 2I759; CE03500; WBGene00010875; WP:CE03500 WormBase description: testis-specific like protein
M18.3 M18.3 P W All gene names: M18.3; 4M871; CE06195; WBGene00010889; WP:CE06195
M18.7 M18.7 P W All gene names: aly-3; M18.7; 4M889; CE06198; NM_069900; Q21559_CAEEL; WBGene00000122; WP:CE06198 WormBase description: RNA recognition motif. (aka RRM, RBD, or RNP domain)
M18.8 M18.8 P W All gene names: M18.8; 4M891; CE32911; WBGene00010892; WP:CE32911
M7.1 M7.1 P W All gene names: let-70; ubc-2; M7.1; 4L846; CE03482; NM_069664; UBC2_CAEEL; WBGene00002344; WP:CE03482 WormBase description: let-70 encodes a class I E2 ubiquitin conjugating enzyme; let-70 was identified in screens for essential genes and phenotypic analyses indicate that loss of let-70 activity results in embryonic and larval lethality with defects in sarcomere assembly; purified LET-70 can stimulate the self-ubiquitylation activities of CHN-1 and UFD-2, E4 ubiquitin conjugation factors and, in addition, can stimulate the CHN-1- and UFD-2-dependent multiubiquitylation of UNC-45, a myosin-directed chaperone; in this manner, LET-70 may regulate UNC-45 degradation and myosin assembly; RNA blot analyses and a let-70-lacZ reporter fusion reveal that let-70 is abundantly expressed at all stages of development, including the dauer larval stage; strong staining is observed in most somatic tissues until adult stages, when expression generally becomes restricted to the nervous system. WormBase CDS description: ubiquitin-conjugating enzyme E2-17 KD
M7.5 M7.5 P W All gene names: atg-7; atgr-7; M7.5; 4L844; CE18887; WBGene00010882; WP:CE18887 WormBase description: Yeast YHX1 like
R03E1.1 R03E1.1 P W All gene names: sym-4; R03E1.1; CE18901; NM_077960; WBGene00006369; WP:CE18901; XO784 WormBase description: WD domain, G-beta repeat (3 domains)
R03E1.2 R03E1.2 P W All gene names: R03E1.2; CE18902; WBGene00010993; WP:CE18902; XO782
R04D3.3 R04D3.3 P W All gene names: R04D3.3; CE06224; WBGene00011011; WP:CE06224; XN908
R04D3.4 R04D3.4 P W All gene names: R04D3.4; CE06225; WBGene00011012; WP:CE06225; XN906
R05D11.3 R05D11.3 P W All gene names: CE-NTF2; ran-4; R05D11.3; 1J167; CE06238; NM_059921; WBGene00004305; WP:CE06238 WormBase description: ran-4 encodes a ortholog of NUCLEAR TRANSPORT FACTOR 2 (NTF2) from S. cerevisiae and metazoa, which is predicted to interact with nucleoporins and to promote transport of RAN-1(+GDP) into the nucleus; RAN-4/NTF2 proteins are paralogous to the N-terminal domain of RasGAP SH3 binding proteins such as Drosophila RASPUTIN, and to delta-5-3-ketosteroid isomerases, while having no homology to Ran proteins per se; RAN-4 is essential for early embryogenesis; in mass RNAi assays, ran-4 is needed for embryonic viability, normally rapid growth, fertility, and normal pronuclear envelopes in the embryo. WormBase CDS description: nuclear transport factor 2 like
R05D11.4 R05D11.4 P W All gene names: R05D11.4; 1J177; CE06239; WBGene00011032; WP:CE06239 WormBase description: ATP dependent RNA helicase
R05D11.5 R05D11.5 P W All gene names: R05D11.5; 1J169; CE27195; WBGene00011033; WP:CE27195
R05D11.6 R05D11.6 P W All gene names: R05D11.6; 1J173; CE32473; WBGene00011034; WP:CE32473
R05D11.7 R05D11.7 P W All gene names: R05D11.7; 1J179; CE06242; WBGene00011035; WP:CE06242
R05D11.8 R05D11.8 P W All gene names: edc-3; R05D11.8; 1J181; CE06243; NM_059927; Q21740_CAEEL; WBGene00011036; WP:CE06243
R05D11.9 R05D11.9 P W All gene names: R05D11.9; 1J171; CE32474; Q95ZR2_CAEEL; WBGene00011037; WP:CE32474
R05F9.10 R05F9.10 P W All gene names: sgt-1; R05F9.10; 2F192; CE04813; Q21746_CAEEL; WBGene00019893; WP:CE04813 WormBase description: TPR domain repeats
R05F9.9 R05F9.9 P W All gene names: R05F9.9; 2F190; CE04812; WBGene00019892; WP:CE04812
R07B7.1 R07B7.1 P W All gene names: clh-6; R07B7.1; 5M542; CE29336; NM_073621; WBGene00000533; WP:CE29336 WormBase description: clh-6 encodes a voltage-gated chloride channel orthologous to the human CLCN7 chloride channel (OMIM:602727, which when mutated lead to osteopetrosis); although the precise role of CLH-6 in C. elegans development and/or behavior is not yet known, CLH-6 expression is detected in two GABA-ergic neurons, RMEL and RMER, suggesting that CLH-6 could play a role in membrane excitability and/or GABA packaging; as CLH-6 is also detected in many non-neuronal tissues, such as the gut and body wall muscle, it could also have a broader role in such as processes as transepithelial transport and muscle excitation. WormBase CDS description: chloride channel
R07B7.3 R07B7.3 P W All gene names: pqn-53; R07B7.3; 5M544; CE06265; NM_073622; Q21793_CAEEL; WBGene00004138; WP:CE06265 WormBase description: The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
R07E5.10 R07E5.10 P W All gene names: pdcd-2; R07E5.10; 3F508; CE03534; CE18125; WBGene00011116; WP:CE03534; WP:CE18125 WormBase description: This gene encodes a homolog of mammalian PROGRAMMED CELL DEATH 2 (PDCD2). WormBase CDS description: Apoptosis protein RP-8
R07E5.11 R07E5.11 P W All gene names: R07E5.11; 3F506; CE00669; WBGene00011117; WP:CE00669
R07E5.7 R07E5.7 P W All gene names: R07E5.7; 3F510; CE00672; WBGene00011115; WP:CE00672
R07H5.1 R07H5.1 P W All gene names: prx-14; R07H5.1; 4L949; CE12550; NM_069696; Q93930_CAEEL; WBGene00004199; WP:CE12550
R07H5.2 R07H5.2 P W All gene names: cpt-2; R07H5.2; 4L947; CE18907; CE40106; WBGene00011122; WP:CE18907; WP:CE40106 WormBase description: R07H5.2 is orthologous to the human gene CARNITINE PALMITOYLTRANSFERASE II (CPT2; OMIM:600650), which when mutated leads to disease.
R07H5.3 R07H5.3 P W All gene names: R07H5.3; 4L951; CE12554; CE35186; WBGene00011123; WP:CE12554; WP:CE35186
R107.2 R107.2 P W All gene names: R107.2; 3K134; CE23917; WBGene00011298; WP:CE23917 WormBase description: Uncharacterized protein family UPF0031
R107.4 R107.4 P W All gene names: ikke-1; R107.4; 3K136; CE31817; CE31818; CE31819; CE37846; WBGene00011299; WP:CE31817; WP:CE31818; WP:CE31819; WP:CE37846; YNH4_CAEEL WormBase description: tyrosine-protein kinase
R10D12.13 R10D12.13 P W All gene names: R10D12.13; 5O445; CE12696; CE23920; CE23921; WBGene00011194; WP:CE12696; WP:CE23920; WP:CE23921
R10D12.14 R10D12.14 P W All gene names: R10D12.14; CE40107; CE40108; WBGene00011195; WP:CE40107; WP:CE40108
R12H7.3 R12H7.3 P W All gene names: skr-19; R12H7.3; CE03568; NM_077792; WBGene00004825; WP:CE03568; XN842 WormBase description: The skr-19 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-19(RNAi) animals are at least superficially normal. WormBase CDS description: RNA polymerase II elongation factor like
R12H7.5 R12H7.5 P W All gene names: skr-20; R12H7.5; CE06317; NM_077791; WBGene00004826; WP:CE06317; XN840 WormBase description: The skr-20 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-20(RNAi) animals are at least superficially normal. WormBase CDS description: RNA polymerase II elongation factor like
R144.3 R144.3 P W All gene names: R144.3; 3G115; CE39271; WBGene00020093; WP:CE39271
R144.4 R144.4 P W All gene names: wip-1; R144.4; 3G109; CE34587; CE34588; WBGene00020094; WP:CE34587; WP:CE34588
R144.9 R144.9 P W All gene names: mdt-11; R144.9; 3G111; CE25092; NM_065665; Q9BI74_CAEEL; WBGene00007015; WP:CE25092
R151.10 R151.10 P W All gene names: R151.10; 3I320; CE27198; WBGene00020113; WP:CE27198
R151.6 R151.6 P W All gene names: R151.6; 3I312; CE39620; DERL2_CAEEL; WBGene00020109; WP:CE39620
R151.7 R151.7 P W All gene names: R151.7; 3I314; CE39621; CE39622; WBGene00020110; WP:CE39621; WP:CE39622 WormBase description: HSP C62.5
R151.8 R151.8 P W All gene names: R151.8; 3I318; CE27201; WBGene00020111; WP:CE27201
R151.9 R151.9 P W All gene names: pfd-5; R151.9; 3H288; 3I288; CE00827; PFD5_CAEEL; WBGene00020112; WP:CE00827
T01B7.3 T01B7.3 P W All gene names: rab-21; T01B7.3; 2J2; CE03587; NM_063453; WBGene00004279; WP:CE03587 WormBase description: ras-related protein
T01B7.4 T01B7.4 P W All gene names: cyn-11; cyp-11; T01B7.4; 2J6; CE03588; NM_063454; WBGene00000887; WP:CE03588 WormBase description: cyp-11 encodes a divergent cyclophilin D isoform, with alterations in the normally well-conserved cyclophilin-binding domain, and a central 7-8 residue insert not usually found in cyclophilins, except from plants; CYP-11 has sluggish but detectable peptidyl-prolyl isomerase activity in vitro, suggesting that it has a specialized substrate in vivo; CYP-11 is dispensable for viability and gross morphology in mass RNAi screens. WormBase CDS description: peptidyl-prolyl cis-trans isomerase
T01C3.8 T01C3.8 P W All gene names: mut-15; T01C3.8; 5P483; CE23936; WBGene00011323; WP:CE23936
T01C3.9 T01C3.9 P W All gene names: T01C3.9; 5P485; CE12924; WBGene00011324; WP:CE12924
T03D8.1 T03D8.1 P W All gene names: num-1; T03D8.1; 5V307; CE18918; CE18919; CE30563; NM_075620; NUMB1_CAEEL; WBGene00003830; WP:CE18918; WP:CE18919; WP:CE30563 WormBase description: Phosphotyrosine interaction domain (PTB/PID).
T03D8.2 T03D8.2 P W All gene names: T03D8.2; 5V309; CE18920; WBGene00011391; WP:CE18920 WormBase description: Ribosomal protein S12
T03F1.2 T03F1.2 P W All gene names: coq-4; T03F1.2; 1E437; CE40117; NM_058845; WBGene00000764; WP:CE40117 WormBase description: coq-4 encodes an ortholog of S. cerevisiae COQ4; while COQ-4 is conserved between eukaryotes and bacteria, its biochemical function is unknown; by orthology, COQ-4 is predicted to peripherally associate with the matrix face of the mitochondrial inner membrane, in a complex with COQ-3 (and perhaps COQ-6), and to be required to maintain a steady-state level of CLK-1/COQ-7 protein; COQ-4 is required for ubiquinone (coenzyme Q9) biosynthesis and for normally short lifespan; coq-4(RNAi) animals have reduced levels of coenzyme Q9 and superoxide, and have abnormally long lifespans.
T03F1.3 T03F1.3 P W All gene names: pgk-1; T03F1.3; 1E435; CE13100; PGK_CAEEL; WBGene00020185; WP:CE13100 WormBase description: T03F1.3 is orthologous to the human gene PHOSPHOGLYCERETE KINASE 1 (PGK1; OMIM:311800), which when mutated leads to hemolytic anemia and neurologic disturbances. WormBase CDS description: phosphoglycerate kinase
T04A8.14 T04A8.14 P W All gene names: emb-5; T04A8.14; 3F806; CE13120; NM_065568; WBGene00001259; WP:CE13120 WormBase description: emb-5 encodes the C. elegans ortholog of the Spt6 family of RNA polymerase II transcription elongation factors; first identified in screens for temperature-sensitive embryonic lethal mutations, emb-5 is required for the correct timing of the second E (endoderm)-cell division in the early embryo and thus, for normal embryonic gastrulation; in addition, emb-5 activity is required postembryonically for proper gonad development; in yeast two-hybrid studies, EMB-5 interacts with the intracellular domains of LIN-12 and GLP-1, suggesting that EMB-5 functions as a positive downstream effector in Notch-like signaling pathways during C. elegans development; emb-5 mRNA is most abundant during embryonic stages, with lower levels apparent during the L1-L3 larval stages, and even lower levels observed during L4. WormBase CDS description: S1 RNA binding domain
T04A8.15 T04A8.15 P W All gene names: T04A8.15; 3F802; CE33538; WBGene00011415; WP:CE33538 WormBase description: glucose-6-phosphate 1-dehydrogenase
T04A8.7 T04A8.7 P W All gene names: T04A8.7; CE01076; CE33539; NM_065560; NM_181902; WBGene00011409; WP:CE01076; WP:CE33539 WormBase description: T04A8.7 is orthologous to human GLUCOSIDASE, ACID BETA (GBA; OMIM:606463), which when mutated leads to Gaucher disease.
T04A8.8 T04A8.8 P W All gene names: T04A8.8; 3F783; CE01077; WBGene00011410; WP:CE01077
T04H1.4 T04H1.4 P W All gene names: rad-50; T04H1.4; 5M731; CE21149; CE41010; NM_073669; RAD50; WBGene00004296; WP:CE21149; WP:CE41010 WormBase description: DNA repair protein RAD50 like
T04H1.5 T04H1.5 P W All gene names: T04H1.5; 5M733; CE13175; WBGene00011451; WP:CE13175
T05E11.1 T05E11.1 P W All gene names: rps-5; T05E11.1; 4L874; CE06360; NM_069676; RS5_CAEEL; WBGene00004474; WP:CE06360 WormBase description: rps-5 encodes a small ribosomal subunit S5 protein. WormBase CDS description: 40S ribosomal protein S5
T05E11.6 T05E11.6 P W All gene names: T05E11.6; 4L872; CE40776; WBGene00011482; WP:CE40776 WormBase description: haemoglobinase like
T05H10.5 T05H10.5 P W All gene names: ufd-2; T05H10.5; 2I357; CE01642; CE28868; CE36948; NM_063290; NM_063291; WBGene00006734; WP:CE01642; WP:CE28868; WP:CE36948
T05H10.6 T05H10.6 P W All gene names: T05H10.6; CE01643; CE32929; NM_063292; NM_182153; WBGene00011510; WP:CE01643; WP:CE32929 WormBase description: T05H10.6 encodes an ortholog of the human gene PYRUVATE DEHYDROGENASE (LIPOAMIDE) ALPHA 1 (PDHA1; OMIM:312170), which when mutated leads to Leigh syndrome (OMIM:256000); the T05H10.6 protein is predicted to be mitochondrial with 68% accuracy.
T05H4.10 T05H4.10 P W All gene names: T05H4.10; CE27439; WBGene00020273; WP:CE27439
T05H4.11 T05H4.11 P W All gene names: T05H4.11; 5G904; CE27440; WBGene00020274; WP:CE27440
T05H4.12 T05H4.12 P W All gene names: atp-4; T05H4.12; 5G906; CE13291; WBGene00020275; WP:CE13291
T05H4.13 T05H4.13 P W All gene names: alh-4; T05H4.13; 5G908; CE27441; CE30827; CE33307; NM_072233; NM_171471; NM_171472; WBGene00000110; WP:CE27441; WP:CE30827; WP:CE33307 WormBase description: aldehyde dehydrogenase
T07A9.5 T07A9.5 P W All gene names: eri-1; T07A9.5; 4B170; CE17214; CE30163; ERI1_CAEEL; NM_171244; NM_171245; WBGene00001332; WP:CE17214; WP:CE30163
T07A9.6 T07A9.6 P W All gene names: daf-18; T07A9.6; 4B174; CE26385; NM_067525; WBGene00000913; WP:CE26385 WormBase description: daf-18 encodes a lipid phosphatase homologous to the human PTEN tumor suppresor (OMIM:601728, mutated in Cowden disease and several cancers); DAF-18 negatively regulates insulin-like signaling mediated by DAF-2/IR and AGE-1/PI3K and thus plays a role in metabolism, development, and longevity; based on sequence and genetic analysis, DAF-18 is predicted to dephosphorylate AGE-1-generated PIP3 in order to limit activation of the downstream AKT-1 and AKT-2 kinases that negatively regulate DAF-16.
T07A9.8 T07A9.8 P W All gene names: T07A9.8; 4B151; CE17217; WBGene00020296; WP:CE17217
T07A9.9 T07A9.9 P W All gene names: phi-58; T07A9.9; 4B149; CE17218; CE31600; CE33689; WBGene00020297; WP:CE17218; WP:CE31600; WP:CE33689
T08G11.1 T08G11.1 P W All gene names: T08G11.1; 1J482; CE13443; CE30353; WBGene00011629; WP:CE13443; WP:CE30353 WormBase description: nucleotide binding protein
T08G11.4 T08G11.4 P W All gene names: T08G11.4; 1J480; CE23958; Q94013_CAEEL; WBGene00011631; WP:CE23958
T08G2.3 T08G2.3 P W All gene names: T08G2.3; CE07473; WBGene00020366; WP:CE07473; XR828 WormBase description: T08G2.3 is orthologous to the human gene ACYL-CoA DEHYDROGENASE, MEDIUM-CHAIN (ACADM; OMIM:607008), which when mutated leads to MCAD deficiency. WormBase CDS description: acyl-CoA dehydrogenase
T09B4.10 T09B4.10 P W All gene names: chn-1; tag-69; T09B4.10; 1G758; CE29991; NM_059380; WBGene00000500; WP:CE29991 WormBase description: chn-1 encodes an ortholog of mammalian carboxyl-terminus of Hsc70 interacting protein (CHIP), an E4 ubiquitin-chain elongation factor; chn-1 is ubiquitously expressed; chn-1(by155) mutants are viable and superficially normal, but have reduced fertility and arrest as larvae if subjected to heat shock; chn-1 overexpression causes either embryonic lethality (if strong) or defective egg-laying and locomotion, along with constitutive dauer formation (if weak); chn-1(by155) mutations suppress viable unc-45(e286ts) and unc-45(m94ts) mutations, but not lethal unc-45(st604) ones; chn-1(by155) mutants, unlike wild-type, show defective sarcomeres if overexpressing unc-45 from a extrachromosomal array; CHN-1 binds the ubiquitin conjugating enzyme UFD-2, which in turn binds the Hsp90 cochaperone UNC-45; UNC-45 is a substrate for CHN-1- and UFD-2-dependent multiubiquitination; the parkin ortholog PDR-1 binds CHN-1, and requires CHN-1 for self-ubiquitination; chn-1(RNAi) animals accumulate abnormally phosphorylated tau proteins.
T09B4.9 T09B4.9 P W All gene names: T09B4.9; 1G754; CE13473; TIM44_CAEEL; WBGene00020383; WP:CE13473
T09E8.2 T09E8.2 P W All gene names: him-17; T09E8.2; 5N659; CE13489; NM_073876; WBGene00001874; WP:CE13489 WormBase description: him-17 encodes a novel chromatin-associated protein required for initiation of meiotic recombination via the formation of double-strand DNA breaks; him-17 mutants have inviable embryos and a high frequency of males in the population; the HIM-17::GFP fusion protein localizes to chromatin in germline nuclei.
T09E8.3 T09E8.3 P W All gene names: T09E8.3; 5N661; CE23961; WBGene00011648; WP:CE23961 WormBase description: cornichon protein like
T10E9.1 T10E9.1 P W All gene names: T10E9.1; 1H121; CE13543; WBGene00020411; WP:CE13543 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
T10E9.2 T10E9.2 P W All gene names: T10E9.2; 1H119; CE13545; WBGene00020412; WP:CE13545
T10H9.3 T10H9.3 P W All gene names: T10H9.3; 5H134; CE18251; O76413_CAEEL; WBGene00020425; WP:CE18251
T10H9.4 T10H9.4 P W All gene names: snb-1; sup-8; T10H9.4; 5H136; CE18252; NM_072287; VAMP/1; WBGene00004897; WP:CE18252 WormBase description: The snb-1 gene encodes synaptobrevin, a synaptic vesicle protein orthologous to human vesicle-associated membrane protein 1 (VAMP1 OMIM:185880) and 2 (VAMP2 OMIM:185881), and is required for viability and synaptic transmission; SNB-1 is likely to play a role in vesicle docking and/or fusion and is expressed in neurons where it colocalizes with synaptic vesicle proteins RAB-3 and synaptotagmin. WormBase CDS description: synaptobrevin
T11G6.1 T11G6.1 P W All gene names: hrs-1; T11G6.1; 4L625; CE06427; CE33829; WBGene00002001; WP:CE06427; WP:CE33829 WormBase description: hrs-1 encodes predicted cytoplasmic and mitochondrial histidyl-tRNA synthetases (HisRS), class II aminoacyl-tRNA synthetases that catalyze the attachment of histidine to its cognate tRNAs and are thus required for protein biosynthesis; HRS-1 synthetases are required for embryogenesis, germline development, wild type body morphology, and normal rates of postembryonic growth. WormBase CDS description: histidyl-tRNA synthetase (mitochondrial)
T11G6.8 T11G6.8 P W All gene names: T11G6.8; 4L627; CE33830; PX1; WBGene00011722; WP:CE33830 WormBase description: RNA recognition motif. (aka RRM, RBD, or RNP domain)
T12F5.2 T12F5.2 P W All gene names: T12F5.2; 1E303; CE13597; WBGene00020467; WP:CE13597
T12F5.3 T12F5.3 P W All gene names: glh-4; T12F5.3; 1E299; CE29052; NM_058806; WBGene00001601; WP:CE29052 WormBase description: glh-4 encodes a putative germline RNA helicase that affects germline proliferation, oogenesis, spermatogenesis, and hence fertility in combination with glh-1, and is partially redundant with glh-1; glh-4 is a constituent of P granules and expression is most abundant in newly fertilized embryos. WormBase CDS description: helicase
T13H5.7 T13H5.7 P W All gene names: rnh-2; T13H5.7; 2I807; CE28960; NM_063395; WBGene00004383; WP:CE28960; rnh2
T13H5.8 T13H5.8 P W All gene names: T13H5.8; 2I809; CE28961; WBGene00011761; WP:CE28961 WormBase description: T13H5.8 is the closest C. elegans homolog of the human gene CRR9, which promotes cisplatin-induced apoptosis in ovarian cancer cells, and of CLPTM1, a human gene associated with cleft lip and palate.
T16G12.5 T16G12.5 P W All gene names: T16G12.5; 3L157; CE23986; WBGene00011806; WP:CE23986
T16G12.6 T16G12.6 P W All gene names: T16G12.6; 3L165; CE00584; WBGene00011807; WP:CE00584
T16H12.4 T16H12.4 P W All gene names: T16H12.4; 3L178; CE29053; TF2H2_CAEEL; WBGene00011814; WP:CE29053 WormBase description: transcription factor IIH subunit
T16H12.5 T16H12.5 P W All gene names: bath-43; T16H12.5; 3L182; CE00510; CE29054; WBGene00011815; WP:CE00510; WP:CE29054 WormBase description: The T16H12.5 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis. WormBase CDS description: Kruppel-like zinc finger protein (outside zinc fingers)
T19B10.11 T19B10.11 P W All gene names: mxl-1; T19B10.11; 5L725; CE16417; NM_073455; WBGene00003509; WP:CE16417 WormBase description: Helix-loop-helix DNA-binding domain
T19B10.7 T19B10.7 P W All gene names: ima-1; T19B10.7; 5L721; CE06461; IMA1_CAEEL; NM_073453; WBGene00002072; WP:CE06461 WormBase description: ima-1 encodes a member of the importin family. WormBase CDS description: importin alpha, nuclear transport factor
T19B10.8 T19B10.8 P W All gene names: T19B10.8; 5L723; CE06462; WBGene00011835; WP:CE06462 WormBase description: Yeast hyptothetical protein YFC5 like
T20B12.7 T20B12.7 P W All gene names: T20B12.7; 3I468; CE01413; WBGene00020604; WP:CE01413
T20B12.8 T20B12.8 P W All gene names: hmg-4; T20B12.8; 3I470; CE01414; NM_066232; WBGene00001974; WP:CE01414 WormBase description: hmg-4 encodes a protein with strong similarity to the highly conserved high mobility group protein SSRP1 (structure-specific DNA recognition protein); by homology, HMG-4 is predicted to be a member of the FACT (facilitates chromatin transcription) complex that functions as a transcription elongation factor; RNAi experiments indicate that hmg-4 is required for locomotion and larval development, and required redundantly with hmg-3, its paralog, for embryonic development.
T20H4.4 T20H4.4 P W All gene names: adr-2; T20H4.4; 3I322; ADR2_CAEEL; CE25120; WBGene00000080; WP:CE25120 WormBase description: adr-2 encodes an adenosine deaminase that acts on RNA (ADAR); ADARs are RNA-editing enzymes that deaminate adenosines to create inosines in double-stranded RNA (dsRNA); adr-2 is expressed ubiquitously in early embryos, as well as in the germline of early adults; ADR-2 is required for ADAR activity in vivo, and for normal chemotaxis.
T20H4.5 T20H4.5 P W All gene names: T20H4.5; 3I324; CE00832; WBGene00020636; WP:CE00832 WormBase description: T20H4.5 gene encodes a 23 kDa subunit of mitochondrial complex I that is required for oxidative phosphorylation and for resistance to volatile anesthetics; T20H4.5 is orthologous to human NDUFS8 (OMIM:602141, mutated in Leigh syndrome). WormBase CDS description: Mitochondrial complex I 23K chain
T21B10.1 T21B10.1 P W All gene names: T21B10.1; 2J221; CE03683; WBGene00011883; WP:CE03683
T21B10.7 T21B10.7 P W All gene names: T21B10.7; 2J219; CE16437; WBGene00011889; WP:CE16437 WormBase description: t-complex protein 1
T21C9.1 T21C9.1 P W All gene names: T21C9.1; 5L56; CE23996; WBGene00011890; WP:CE23996 WormBase description: discs large like repeats
T21C9.2 T21C9.2 P W All gene names: vps-54; T21C9.2; 5L46; CE31365; NM_073310; WBGene00006934; WP:CE31365 WormBase description: The vps-54 gene encodes an ortholog of VPS54 in S. cerevisiae, a protein involved in vacuolar trafficking. WormBase CDS description: Zinc finger, C2H2 type
T21C9.4 T21C9.4 P W All gene names: T21C9.4; 5L58; CE06473; ERH_CAEEL; WBGene00011892; WP:CE06473 WormBase description: Enhancer of rudimentary
T23B12.1 T23B12.1 P W All gene names: T23B12.1; 5I951; CE14026; WBGene00020716; WP:CE14026
T23B12.2 T23B12.2 P W All gene names: T23B12.2; 5I949; CE14028; O17005_CAEEL; WBGene00020717; WP:CE14028 WormBase description: ribosomal protein
T23B12.3 T23B12.3 P W All gene names: T23B12.3; 5I947; CE14030; WBGene00020718; WP:CE14030 WormBase description: ribosomal protein
T23B12.4 T23B12.4 P W All gene names: T23B12.4; 5I945; CE29351; WBGene00020719; WP:CE29351
T23G7.2 T23G7.2 P W All gene names: T23G7.2; 2J458; CE35908; WBGene00011965; WP:CE35908
T23G7.3 T23G7.3 P W All gene names: T23G7.3; 2J456; CE03704; WBGene00011966; WP:CE03704
T24F1.1 T24F1.1 P W All gene names: tag-29; T24F1.1; 2L593; CE02361; WBGene00006414; WP:CE02361 WormBase description: GTP-binding protein
T24F1.2 T24F1.2 P W All gene names: T24F1.2; 2L595; CE02362; Q22747_CAEEL; WBGene00011994; WP:CE02362
T25G12.5 T25G12.5 P W All gene names: T25G12.5; CE18284; WBGene00020812; WP:CE18284; XR830 WormBase description: acyl-CoA dehydrogenase
T26H10.1 T26H10.1 P W All gene names: acr-4; des-2; T26H10.1; CE21208; NM_073497; WBGene00000955; WP:CE21208 WormBase description: des-2 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR), predicted to be a ligand-gated ion channel regulating the fast action of acetylcholine at neuromuscular junctions and in the nervous system; DES-2 is coexpressed with and genetically interacts with DEG-3, which which it probably forms heteromultimers, and DES-2 falls into the 'DEG-3' class of nAChR subunits, probably unique to nematodes, which includes DEG-3, ACR-5, ACR-17, ACR-18 ACR-20, and ACR-23. WormBase CDS description: nicotinic acetylcholine receptor
T27D1.1 T27D1.1 P W All gene names: cyn-9; cyp-9; T27D1.1; 3E788; CE03745; NM_065344; WBGene00000885; WP:CE03745 WormBase description: The cyp-9 gene encodes a peptidyl prolyl cis-trans isomerase most similar to human cyclophilin G (OMIM:606093); CYP-9 likely functions as a catalyst in the folding and modification of cuticle collagens and is expressed in the cuticle synthesizing syncytial hypodermis most strongly at the mid-L3 and mid-L4 larval stages, the intermoult period when collagens are synthesized. WormBase CDS description: cyclophilin related protein
T28A8.5 T28A8.5 P W All gene names: T28A8.5; 3O591; CE18976; WBGene00012111; WP:CE18976
T28A8.6 T28A8.6 P W All gene names: T28A8.6; 3O589; CE18977; WBGene00012112; WP:CE18977
T28H10.1 T28H10.1 P W All gene names: T28H10.1; 5M985; CE06529; WBGene00012142; WP:CE06529 WormBase description: B.subtilis SFP protein like
VF39H2L.1 VF39H2L.1 P W All gene names: VF39H2L.1; 1J221; CE18300; WBGene00012150; WP:CE18300
VW02B12L.3 VW02B12L.3 P W All gene names: ebp-2; VW02B12L.3; 2L733; CE18982; Q9XXA2_CAEEL; WBGene00012156; WP:CE18982
VW02B12L.4 VW02B12L.4 P W All gene names: adbp-1; VW02B12L.4; 2L735; 2L737; CE26728; Q23129_CAEEL; WBGene00012157; WP:CE26728
W02B12.10 W02B12.10 P W All gene names: W02B12.10; 2L762; CE03770; TRMB_CAEEL; WBGene00012205; WP:CE03770
W02B12.9 W02B12.9 P W All gene names: W02B12.9; 2L760; CE03769; WBGene00012204; WP:CE03769 WormBase description: mitochondrial RNA splicing MSR4 like protein
W02D3.10 W02D3.10 P W All gene names: W02D3.10; 1H326; CE34383; CE34384; WBGene00020935; WP:CE34383; WP:CE34384
W02D3.11 W02D3.11 P W All gene names: F08B6.D; W02D3.11; 1H330; CE26020; CE31078; Q9BIB7_CAEEL; WBGene00020936; WP:CE26020; WP:CE31078 WormBase description: W02D3.11 encodes, by alternative splicing, two protein isoforms orthologous to human hnRNP F and hnRNP H proteins, which activate alternative mRNA splicing in neurons; W02D3.11A-B proteins localize to nuclear speckles thought to represent foci of pre-mRNA; with EXC-7 and UNC-75, W02D3.11A-B may act as pre-mRNA splicing factors.
W04D2.4 W04D2.4 P W All gene names: W04D2.4; 5M976; CE06541; WBGene00012243; WP:CE06541 WormBase description: Zinc finger, C2H2 type
W04D2.5 W04D2.5 P W All gene names: W04D2.5; 5M974; CE06542; WBGene00012244; WP:CE06542 WormBase description: mitochondrial ribosomal protein S11 like
W04D2.6 W04D2.6 P W All gene names: W04D2.6; 5M983; CE32000; CE32001; WBGene00012245; WP:CE32000; WP:CE32001 WormBase description: RNA recognition motif. (aka RRM, RBD, or RNP domain)
W05H7.3 W05H7.3 P W All gene names: sedl-1; W05H7.3; CE14652; NM_075871; WBGene00021046; WP:CE14652; XC58
W05H7.4 W05H7.4 P W All gene names: W05H7.4; CE33719; CE35046; CE35047; CE38431; CE38432; Q8MPS9_CAEEL; WBGene00021047; WP:CE33719; WP:CE35046; WP:CE35047; WP:CE38431; WP:CE38432; XC60
W06D4.1 W06D4.1 P W All gene names: hgo-1; W06D4.1; 1J626; CE29602; HGD_CAEEL; HGO; NM_060032; WBGene00001843; WP:CE29602 WormBase description: hgo-1 is orthologous to the human gene SIMILAR TO HOMOGENTISATE 1,2-DIOXYGENASE (HOMOGENTISATE OXIDASE) (HGD; OMIM:203500), which when mutated leads to disease. WormBase CDS description: HOMOGENTISATE 1,2-DIOXYGENASE (EC 220.127.116.11) (HOMOGENTISICASE) (HOMOGENTISATE OXYGENASE) (HOMOGENTISIC ACID OXIDASE)
Y102E9.2 Y102E9.2 P W All gene names: Y102E9.2; 3H815; CE07574; Q23232_CAEEL; WBGene00022420; WP:CE07574
Y106G6E.4 Y106G6E.4 P W All gene names: Y106G6E.4; 1K796; CE20408; WBGene00013708; WP:CE20408 WormBase description: 5-formyltetrahydrofolate cyclo-ligase
Y106G6E.5 Y106G6E.5 P W All gene names: ced-12; mig-16; Y106G6E.5; 1K800; CE27228; NM_060292; WBGene00000426; WP:CE27228 WormBase description: ced-12 is required both for phagocytotic engulfment of dying (apoptotic) cells, and for normal migrations of healthy cells during development.
Y39A1A.20 Y39A1A.20 P W All gene names: Y39A1A.20; 3L788; CE34114; WBGene00012657; WP:CE34114
Y39A1A.21 Y39A1A.21 P W All gene names: Y39A1A.21; 3L790; CE19141; WBGene00012658; WP:CE19141
Y48A6B.3 Y48A6B.3 P W All gene names: Y48A6B.3; 3M97; CE19186; NOLA2_CAEEL; WBGene00012964; WP:CE19186 WormBase description: Ribosomal protein L7Ae
Y48A6B.5 Y48A6B.5 P W All gene names: Y48A6B.5; 3M99; CE19188; WBGene00012966; WP:CE19188
Y49A3A.2 Y49A3A.2 P W All gene names: phi-51; vha-13; Y49A3A.2; Y49A3A.B; Y49A3A.C; CE22210; NM_074158; WBGene00013025; WP:CE22210 WormBase description: vha-13 encodes an ortholog of subunit A of the cytoplasmic (V1) domain of vacuolar proton-translocating ATPase (V-ATPase); VHA-13 is predicted to hydrolyse ATP as part of a cytosolic VHA-12/VHA-13 heterohexamer, whose activity drives the V-ATPase rotor; VHA-13 levels are lowered in mutants with either abnormally low or abnormally high calcineurin levels, and elevated in mutants lacking both calcineurin and calreticulin; VHA-13 is dispensable for alae formation, like the V1 subunit VHA-8, but not like the V0 subunits VHA-1 and VHA-4. WormBase CDS description: ATP synthase alpha and beta subunits ; ATP synthase ab C terminal
Y49A3A.3 Y49A3A.3 P W All gene names: Y49A3A.3; CE22211; NM_074159; WBGene00013026; WP:CE22211 WormBase description: Y49A3A.3 encodes a conserved but uncharacterized protein with some similarity to Barwin-related endoglucanase; Y49A3A.3 shares an operon with vha-13, and thus might be a previously undescribed V-ATPase component or ancillary protein.
Y53C12A.3 Y53C12A.3 P W All gene names: Y53C12A.3; 2J994; CE14888; WBGene00013139; WP:CE14888
Y53C12A.4 Y53C12A.4 P W All gene names: mop-25.2; lss-18; Y53C12A.4; 2J992; CE14890; WBGene00013140; WP:CE14890 WormBase description: Mouse MO25 protein like
Y5F2A.4 Y5F2A.4 P W All gene names: Y5F2A.4; 4L842; CE19025; WBGene00012385; WP:CE19025 WormBase description: Zinc finger, C2H2 type (7 domains)
Y6D11A.1 Y6D11A.1 P W All gene names: Y6D11A.1; 3B479; CE30059; NM_064878; WBGene00000202; WP:CE30059
ZC410.7 ZC410.7 P W All gene names: lpl-1; ZC410.7; 4J858; CE26842; CE26843; CE36255; NM_069179; Ny; WBGene00003066; WP:CE26842; WP:CE26843; WP:CE36255 WormBase description: The lpl-1 gene encodes a lipoate ligase homolog; this gene resides in an operon that also contains the genes icl-1 and C01F6.9.
ZC434.5 ZC434.5 P W All gene names: ers-2; qrs-3; ZC434.5; 1K915; CE06580; NM_060310; WBGene00001337; WP:CE06580 WormBase description: ers-2 encodes a predicted mitochondrial glutamyl-tRNA synthetase (GluRS), a class I aminoacyl-tRNA synthetase that catalyzes the attachment of glutamate to its cognate tRNA and is thus required for protein biosynthesis; ERS-2 contains, at its C-terminus, six tandemly repeated WHEP-TRS domains that have been predicted to function as general RNA-binding domains that may act as cis tRNA-binding cofactors. WormBase CDS description: glutamyl-trna synthetase
ZC434.6 ZC434.6 P W All gene names: aph-2; ZC434.6; 1K921; CE34446; NM_060311; WBGene00000148; WP:CE34446 WormBase description: aph-2 encodes an ortholog of nicastrin, which associates with presenilin and membrane-bound Notchl in aph-2 mutants, the specification of pi-cells is compromised.
ZC434.7 ZC434.7 P W All gene names: ZC434.7; 1K923; CE06582; CE41088; WBGene00013893; WP:CE06582; WP:CE41088
ZK1058.3 ZK1058.3 P W All gene names: ZK1058.3; 3F9; CE01103; WBGene00014203; WP:CE01103 WormBase description: ZK1058.3 is orthologous to the human gene UNNAMED PROTEIN PRODUCT (GALT; OMIM:606999), which when mutated leads to disease. WormBase CDS description: galactose-1-phosphate uridylyltransferase
ZK1058.4 ZK1058.4 P W All gene names: tag-252; ZK1058.4; 3F7; CE01104; Q23382_CAEEL; WBGene00014204; WP:CE01104
ZK1236.6 ZK1236.6 P W All gene names: pqn-96; ZK1236.6; 3J528; CE00383; NM_066465; WBGene00004175; WP:CE00383 WormBase description: The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
ZK1236.7 ZK1236.7 P W All gene names: ZK1236.7; 3J530; CE29628; WBGene00022865; WP:CE29628
ZK20.3 ZK20.3 P W All gene names: ZK20.3; 2L942; CE06606; WBGene00013924; WP:CE06606 WormBase description: RAD23 protein homolog2 like
ZK20.4 ZK20.4 P W All gene names: ZK20.4; 2L940; CE06607; WBGene00013925; WP:CE06607
ZK353.6 ZK353.6 P W All gene names: lap-1; ZK353.6; 3J490; AMPL_CAEEL; CE00390; NM_066453; WBGene00002249; WP:CE00390 WormBase description: The lap-1 gene encodes a homolog of the zinc metalloprotease leucine aminopeptidase LAP that is predicted to be mitochondrial. WormBase CDS description: Leucine aminopeptidase
ZK353.7 ZK353.7 P W All gene names: ZK353.7; 3J492; CE00391; CUTC_CAEEL; WBGene00022702; WP:CE00391
ZK353.8 ZK353.8 P W All gene names: ubxn-4; ZK353.8; 3J494; CE00392; WBGene00022703; WP:CE00392
ZK484.3 ZK484.3 P W All gene names: ZK484.3; 1G646; CE15341; WBGene00022749; WP:CE15341
ZK484.4 ZK484.4 P W All gene names: ZK484.4; 1G648; CE27354; CE27355; WBGene00022750; WP:CE27354; WP:CE27355
ZK546.13 ZK546.13 P W All gene names: mdt-4; ZK546.13; 2F232; CE34460; WBGene00007012; WP:CE34460
ZK546.14 ZK546.14 P W All gene names: ZK546.14; 2F234; CE02914; CE33503; WBGene00022765; WP:CE02914; WP:CE33503
ZK637.2 ZK637.2 P W All gene names: ZK637.2; 3J979; CE32292; WBGene00014022; WP:CE32292
ZK637.3 ZK637.3 P W All gene names: tag-256; ZK637.3; 3J981; CE00434; WBGene00014023; WP:CE00434
ZK637.4 ZK637.4 P W All gene names: ZK637.4; 3J983; CE00435; WBGene00014024; WP:CE00435
ZK856.10 ZK856.10 P W All gene names: ZK856.10; 5K686; CE06667; WBGene00014111; WP:CE06667 WormBase description: DNA directed RNA polymerase III
ZK856.11 ZK856.11 P W All gene names: ZK856.11; 5K684; CE06668; Q23646_CAEEL; WBGene00014112; WP:CE06668
ZK856.13 ZK856.13 P W All gene names: tag-315; ZK856.13; 5K688; CE29016; WBGene00014114; WP:CE29016 WormBase description: transcription factor
ZK856.8 ZK856.8 P W All gene names: ZK856.8; 5K682; CE06665; WBGene00014109; WP:CE06665 WormBase description: EF-hand calcium binding protein
ZK856.9 ZK856.9 P W All gene names: tag-143; ZK856.9; 5K692; CE29017; WBGene00006489; WBGene00014110; WP:CE29017
ZK863.3 ZK863.3 P W All gene names: ZK863.3; 5M660; CE40344; WBGene00014123; WP:CE40344 WormBase description: Yeast LPG22P protein like
ZK863.4 ZK863.4 P W All gene names: ZK863.4; 5M662; CE23469; WBGene00014124; WP:CE23469