Steina et al 2007, Enriched uncharacterized human , 108 genes Gene list file name: Stetina2007_supp24 Type of gene identifier: Cosmid name Description: 108 unique transcripts from all enriched datasets (EP, LP, EA, LA) that have uncharacterized human homologs Organism: Caenorhabditis elegans (nematode) Gene list type: Experimental Gene name Source Gene ID All gene names WormBase description WormBase CDS description Proteome description Member of lists () Other annotations AC3.3 AC3.3 abu-1; pqn-1; AC3.3; 5K858; CE05133; NM_073266; Q17400_CAEEL; WBGene00000024; WP:CE05133 abu-1 encodes a transmembrane protein with a predicted signal sequence, a glutamine/asparagine-rich domain and multiple cysteine-rich repeats (DUF139); abu-1 expression is induced by blockage of the unfolded-protein response in the endoplasmic reticulum, and ABU-1 may help protect the organism from damage by improperly folded nascent protein. B0024.8 B0024.8 B0024.8; 5K780; CE25738; WBGene00007098; WP:CE25738 C03C10.6 C03C10.6 C03C10.6; CE30720; NM_065416; WBGene00007272; WP:CE30720 C06H2.3 C06H2.3 C06H2.3; 5L609; CE05235; WBGene00007387; WP:CE05235 Acetyltransferase (GNAT) family C07H6.2 C07H6.2 C07H6.2; 3I609; CE00756; WBGene00015579; WP:CE00756 C11H1.7 C11H1.7 C11H1.7; CE18492; WBGene00007531; WP:CE18492; XO945 C13F10.4 C13F10.4 C13F10.4; 5H686; CE08145; WBGene00015743; WP:CE08145 C14C11.8 C14C11.8 pqn-13; C14C11.8; 5G150; CE36269; NM_072093; WBGene00004104; WP:CE36269 The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77). C17H12.2 C17H12.2 C17H12.2; 4H552; CE16863; WBGene00015928; WP:CE16863 C25D7.8 C25D7.8 C25D7.8; 5P547; CE08394; OTUBL_CAEEL; WBGene00007718; WP:CE08394 C28H8.1 C28H8.1 C28H8.1; 3H17; CE01820; WBGene00016192; WP:CE01820 C28H8.1 is orthologous to the human gene BCL7A (OMIM:601406), which when mutated leads to high-grade B-cell non-Hodgkin lymphoma. C32D5.6 C32D5.6 C32D5.6; 2G622; CE01846; WBGene00016314; WP:CE01846 C36E6.2 C36E6.2 C36E6.2; CE34268; WBGene00016490; WP:CE34268; XS69 C38H2.1 C38H2.1 C38H2.1; 3L461; CE32601; WBGene00008018; WP:CE32601 Probable rabGAP domains C40H1.6 C40H1.6 C40H1.6; 3K421; CE00114; UFC1_CAEEL; WBGene00008041; WP:CE00114 C44E4.5 C44E4.5 C44E4.5; 1F177; CE08719; WBGene00016654; WP:CE08719 C50F4.16 C50F4.16 C50F4.16; 5K18; CE28213; WBGene00008238; WP:CE28213 The C50F4.16 gene encodes a NUDIX hydrolase. C56G7.3 C56G7.3 C56G7.3; 3E481; CE17608; WBGene00008348; WP:CE17608 D1007.15 D1007.15 D1007.15; 1F131; CE34284; WBGene00017010; WP:CE34284 D1043.1 D1043.1 D1043.1; 2L877; CE32842; WBGene00008361; WP:CE32842 D2007.5 D2007.5 D2007.5; 3J246; CE00130; WBGene00017045; WP:CE00130 D2013.2 D2013.2 wdfy-2; D2013.2; 2J611; CE00928; WBGene00008402; WP:CE00928; YLN2_CAEEL beta-transducin E04F6.2 E04F6.2 E04F6.2; 2H491; CE01214; WBGene00017122; WP:CE01214 F07H5.8 F07H5.8 F07H5.8; 2J93; CE40935; WBGene00008559; WP:CE40935 keratin like F09E8.2 F09E8.2 F09E8.2; 4N916; CE05579; WBGene00008624; WP:CE05579 F09G8.5 F09G8.5 F09G8.5; 3J345; CE00526; WBGene00017320; WP:CE00526 F20D1.1 F20D1.1 F20D1.1; CE09494; Q93533_CAEEL; WBGene00008973; WP:CE09494; XP588 F23B2.4 F23B2.4 daf-10; osm-4; F23B2.4; 4J898; CE40504; NM_069190; WBGene00000906; WBGene00009074; WP:CE40504 Uncloned locus that affects the development of amphid and phasmid neurons, dauer development, life span, chemotaxis, and nose touch response. WD domain, G-beta repeats F25H2.4 F25H2.4 F25H2.4; 1L129; CE09649; Q93568_CAEEL; WBGene00009118; WP:CE09649 F26A3.1 F26A3.1 F26A3.1; 1I216; CE20724; WBGene00009140; WP:CE20724 F26F4.1 F26F4.1 F26F4.1; 3G3; CE01257; Q19824_CAEEL; WBGene00017825; WP:CE01257 F29A7.4 F29A7.4 F29A7.4; 2D41; CE36835; WBGene00017914; WP:CE36835 F35D11.3 F35D11.3 F35D11.3; 2E901; CE31803; WBGene00018044; WP:CE31803 F41D9.1 F41D9.1 F41D9.1; CE30984; WBGene00018281; WP:CE30984; XJ1 F42F12.4 F42F12.4 F42F12.4; CE16031; WBGene00009636; WP:CE16031; XM970 F42H11.1 F42H11.1 F42H11.1; 1K153; CE10330; WBGene00009646; WP:CE10330 F49E10.1 F49E10.1 F49E10.1; CE29965; WBGene00018639; WP:CE29965; XG519 F53H8.4 F53H8.4 sms-2; F53H8.4; CE04657; NM_075781; SMS2_CAEEL; WBGene00004893; WP:CE04657; XB564 F55A11.1 F55A11.1 F55A11.1; 5M244; CE05943; WBGene00010075; WP:CE05943 EF hand domains F56A11.5 F56A11.5 F56A11.5; 4B322; CE17120; O44517_CAEEL; WBGene00018925; WP:CE17120 F57B10.9 F57B10.9 F57B10.9; 1H128; CE30546; WBGene00019006; WP:CE30546 F57B10.9 is orthologous to the human gene SPARTIN (TAHCCP1; OMIM:607111), which when mutated leads to disease. F57H12.7 F57H12.7 mec-17; F57H12.7; 4I750; CE17128; NM_068936; WBGene00003178; WP:CE17128 mec-17 encodes a protein that has no clearly recognizable motifs yet shares a domain of similarity with an additional C. elegans protein as well as proteins from Drosophila, mouse, and human; MEC-17 activity is required for maintaining the differentiated state of the touch receptors, and hence the animal's touch sensitivity, during later stages of larval development; mec-17 is expressed solely in the touch receptor cells from late embryogenesis through adulthood, and this expression is dependent upon the MEC-3 LIM homeodomain transcription factor; in turn, as MEC-17 is necessary for maintaining differentiated touch receptors, its activity is required for continued expression of MEC-3 and the MEC-7 beta-tubulin. F59E12.11 F59E12.11 F59E12.11; 2F938; CE28570; O01902_CAEEL; WBGene00019126; WP:CE28570 K02B2.3 K02B2.3 K02B2.3; 4G702; CE27192; WBGene00019296; WP:CE27192 K02F3.10 K02F3.10 K02F3.10; 3B468; CE01346; WBGene00019333; WP:CE01346 K03E6.4 K03E6.4 K03E6.4; CE07330; Q21191_CAEEL; WBGene00019364; WP:CE07330; XB686 K04B12.3 K04B12.3 K04B12.3; 2O731; CE37027; WBGene00010551; WP:CE37027 M02G9.3 M02G9.3 M02G9.3; 2K609; CE20017; WBGene00010832; WP:CE20017 M195.2 M195.2 M195.2; 2I653; CE34950; WBGene00010948; WP:CE34950 R07E5.12 R07E5.12 R07E5.12; WBGene00011118 R07G3.8 R07G3.8 R07G3.8; 2H910; CE02027; Q09387_CAEEL; WBGene00019944; WP:CE02027 R09B5.5 R09B5.5 pqn-54; R09B5.5; 5B943; CE12626; NM_071022; O44606_CAEEL; WBGene00004139; WP:CE12626 The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77). R12C12.6 R12C12.6 R12C12.6; 2G336; CE02851; CE39619; WBGene00020026; WP:CE02851; WP:CE39619 R166.3 R166.3 R166.3; 2K828; CE03582; WBGene00011303; WP:CE03582 The R166.3 gene encodes an unfamiliar protein, with homologs in yeast and archaea, that is orthologous to the human gene ALPORT SYNDROME, MENTAL RETARDATION, MIDFACE HYPOPLASIA, AND ELLIPTOCYTOSIS CHROMOSOMAL REGION GENE 1 (AMMECR1; OMIM:300195); AMMECR1, when mutated, may be at least partially responsible for mental retardation, midface hypoplasia, or elliptocytosis. R186.1 R186.1 R186.1; 5N442; CE12870; WBGene00011305; WP:CE12870 T03G11.3 T03G11.3 T03G11.3; CE39762; WBGene00020196; WP:CE39762; XF795 T09B9.4 T09B9.4 T09B9.4; CE01652; WBGene00011645; WP:CE01652; XK390; YRU4_CAEEL T09B9.4 is orthologous to the human gene PUTATIVE CYTOSKELETAL PROTEIN (D10S170; OMIM:601985), which when mutated leads to disease. T10B11.6 T10B11.6 T10B11.6; 1H520; CE18245; Q9TZH8_CAEEL; WBGene00020402; WP:CE18245 T10B11.9 T10B11.9 T10B11.9; WBGene00020405 T16G1.11 T16G1.11 eif-3.K; pqn-69; T16G1.11; 5N435; CE20081; NM_073840; WBGene00001233; WP:CE20081 The protein product of this gene was predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS72 release of WormBase, i.e., in wormpep77). T23B3.3 T23B3.3 T23B3.3; 1H289; CE14012; WBGene00020711; WP:CE14012 T24H10.4 T24H10.4 T24H10.4; 2J401; CE35030; WBGene00012002; WP:CE35030 T24H7.3 T24H7.3 T24H7.3; 2G537; CE02885; Q22757_CAEEL; WBGene00020782; WP:CE02885 T26A8.2 T26A8.2 T26A8.2; 4J193; CE07548; WBGene00020825; WP:CE07548 W02A11.2 W02A11.2 W02A11.2; 1N326; CE24025; WBGene00012193; WP:CE24025 W06B11.1 W06B11.1 W06B11.1; CE28508; WBGene00021059; WP:CE28508; XG469 W08A12.4 W08A12.4 W08A12.4; 5E153; CE14702; WBGene00021081; WP:CE14702 Y105E8A.5 Y105E8A.5 bbs-1; Y105E8A.5; 1O962; CE25181; NM_170937; WBGene00000241; WP:CE25181 Y108G3AL.3 Y108G3AL.3 Y108G3AL.3; 5A642; CE29094; WBGene00022435; WP:CE29094 Y20F4.4 Y20F4.4 Y20F4.4; 1C602; CE30313; WBGene00021239; WP:CE30313 Y37E11B.3 Y37E11B.3 Y37E11B.3; 4E346; CE19613; WBGene00021376; WP:CE19613 Y37E3.1 Y37E3.1 Y37E3.1; 1C630; CE26836; WBGene00021346; WP:CE26836 Y38F2AL.2 Y38F2AL.2 Y38F2AL.2; 4D70; CE21622; Q9N423_CAEEL; WBGene00021416; WP:CE21622 Y50D4B.2 Y50D4B.2 Y50D4B.2; 5B579; CE24401; WBGene00021741; WP:CE24401 Y54E10A.12 Y54E10A.12 Y54E10A.12; 1D762; CE24441; WBGene00021832; WP:CE24441 Y54G11A.4 Y54G11A.4 Y54G11A.4; 2O583; CE22475; WBGene00013215; WP:CE22475 Y54G11A.7 Y54G11A.7 Y54G11A.7; 2O589; CE32990; WBGene00013216; WP:CE32990 Y57A10A.29 Y57A10A.29 Y57A10A.29; 2M571; CE22606; WBGene00013269; WP:CE22606 Y67D2.3 Y67D2.3 Y67D2.3; 3C631; CE27308; WBGene00022053; WP:CE27308 Y71F9B.2 Y71F9B.2 Y71F9B.2; Y71F9B.O; 1D303; CE28809; MMP37_CAEEL; WBGene00022126; WP:CE28809 Y71H2AM.10 Y71H2AM.10 Y71H2AM.10; 3D798; CE29141; WBGene00022175; WP:CE29141 Y71H2AM.6 Y71H2AM.6 Y71H2AM.6; 3D871; CE22938; WBGene00022171; WP:CE22938 Y71H2B.6 Y71H2B.6 mdt-19; Y71H2B.6; Y71H2_389.C; 3D691; CE22945; NM_065186; Q9N4F2_CAEEL; WBGene00007019; WP:CE22945 Y74C9A.5 Y74C9A.5 Y74C9A.5; 1A502; CE40291; WBGene00022279; WP:CE40291 Y75B8A.12 Y75B8A.12 bbs-7; osm-12; Y75B8A.12; 3N280; CE23024; NM_067184; Q9XW70_CAEEL; WBGene00003892; WP:CE23024 Y97E10AR.6 Y97E10AR.6 Y97E10AR.6; 5I494; CE27417; WBGene00022401; WP:CE27417 Y9C12A.1 Y9C12A.1 Y9C12A.1; CE24699; WBGene00021185; WP:CE24699; XB300 ZK1067.7 ZK1067.7 pqn-95; ZK1067.7; 2J516; CE40244; NM_063565; Q23390_CAEEL; WBGene00004174; WP:CE40244 The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77). ZK1236.2 ZK1236.2 cec-1; ZK1236.2; 3J517; CE00380; NM_066461; WBGene00000414; WP:CE00380 cec-1 encodes a nuclear protein with a chromodomain that is ubiquitously expressed in somatic cells, but is dispensable for embryonic survival or gross adult morphology. Nucleolin ZK652.3 ZK652.3 tag-277; ZK652.3; 3I949; CE00449; WBGene00022784; WBGene00044324; WP:CE00449 ZK688.9 ZK688.9 ZK688.9; 3I972; CE40006; WBGene00022803; WP:CE40006 ZK973.11 ZK973.11 ZK973.11; 1E948; CE29654; WBGene00022836; WP:CE29654 thioredoxin