|Gene list file name:||PauliF2006_ST3_271_known-intestine-genes|
|Type of gene identifier:||Cosmid name|
|Description:||PauliF et al 2006, Sup. Table 3. 271 intestine-expressed genes with known anatomical expression pattern. http://elegans.bcgsc.ca/perl/eprofile/index|
|Organism:||Caenorhabditis elegans (nematode)|
|Gene list type:||Experimental|
Gene name Source Gene ID Annotation Date Added by
B0025.2 B0025.2 P W All gene names: csn-2; B0025.2; B0025.2.1; B0025.2.2; B0025.2.3; 1G601; CE27562; CSN2_CAEEL; NM_059339; WBGene00000814; WP:CE27562 WormBase description: csn-2 encodes a homolog of COP9 signalosome complex subunit 2 that affects embryonic viability and growth rate.
B0041.5 B0041.5 P W All gene names: B0041.5; 1F218; CE29527; WBGene00015009; WP:CE29527
B0213.2 B0213.2 P W All gene names: nlp-27; B0213.2; 5E467; CE16773; NM_071710; WBGene00003765; WP:CE16773 WormBase description: nlp-27 encodes a predicted neuropeptide with homology to C. elegans nlp-28 through nlp-31.
B0213.4 B0213.4 P W All gene names: nlp-29; B0213.4; 5E461; CE16775; NLP29_CAEEL; NM_071708; WBGene00003767; WP:CE16775
B0213.5 B0213.5 P W All gene names: nlp-30; B0213.5; CE16776; NLP30_CAEEL; NM_071707; WBGene00003768; WP:CE16776 WormBase description: nlp-30 encodes five predicted neuropeptide-like proteins; in C. elegans, nlp-30 is part of the YGGWamide neuropeptide family that also contains nlp-24, nlp-25, and nlp-27-32; nlp-30 is expressed in the hypodermis, suggesting that the peptides it encodes may have a non-neuronal function; as loss of nlp-30 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of the nlp-30-encoded peptides in development and/or behavior is not yet known.
B0218.8 B0218.8 P W All gene names: clec-52; B0218.8; 4I932; CE06691; WBGene00015052; WP:CE06691 WormBase description: 7TM chemoreceptor, clec family
B0228.7 B0228.7 P W All gene names: B0228.7; 2I48; CE34630; MTAP_CAEEL; WBGene00015064; WP:CE34630
B0252.2 B0252.2 P W All gene names: asm-1; B0252.2; 2H201; ASM1_CAEEL; CE30230; NM_063014; WBGene00000211; WP:CE30230 WormBase description: asm-1 encodes a protein similar to human acid sphingomyelinase (ASM) or sphingomyelin phosphodiesterase; the ASM-1 protein has a putative secretory signal peptide at the N-terminus, saposin-like and proline-rich domains and putative N-linked glycosylation sites; asm-1 shows phosphodiesterase activity when expressed in COS-7 cells; while mammalian ASM is detected as both intracellular and secreted forms, asm-1 was detected exclusively in the secreted form; northern blot analysis indicates that asm-1 is expressed at higher levels in the embryo compared with other stages. WormBase CDS description: Spingomyelin phosphodiesterase
B0272.3 B0272.3 P W All gene names: B0272.3; CE00852; HCDH2_CAEEL; WBGene00007129; WP:CE00852; XK51 WormBase description: 3-hydroxyacyl-CoA dehydrogenase
B0280.3 B0280.3 P W All gene names: B0280.3; B0280.3.1; B0280.3.2; 3I213; CE00733; RPIA_CAEEL; WBGene00015101; WP:CE00733
B0285.3 B0285.3 P W All gene names: B0285.3; 3F432; CE00667; WBGene00007136; WP:CE00667; YKG3_CAEEL
B0334.4 B0334.4 P W All gene names: B0334.4; 2L787; CE02936; WBGene00007144; WP:CE02936 WormBase description: Yeast hypothetical protein L8167.12 like
B0336.2 B0336.2 P W All gene names: arf-1.2; arf-1; B0336.2; B0336.2.1; B0336.2.2; 3G805; ARF/1; ARF12_CAEEL; CE00696; NM_065834; WBGene00000182; WP:CE00696 WormBase description: arf-1 encodes an ADP-ribosylation factor homolog required in vivo for embryonic development, fertility, locomotion, vulval development, and cuticular synthesis; ARF proteins are N-myristoylated GTPases that regulate membrane traffic and the actin cytoskeleton, and that activate both phospholipase D1 (PLD1) and phosphatidylinositol 4-phosphate 5-kinase. WormBase CDS description: ARF
B0336.7 B0336.7 P W All gene names: B0336.7; B0336.7b.1; B0336.7b.2; 3G784; CE29546; CE37741; Q10930_CAEEL; WBGene00015147; WP:CE29546; WP:CE37741
B0416.5 B0416.5 P W All gene names: B0416.5; B0416.5a.1; B0416.5a.2; CE02435; CE29548; WBGene00015181; WP:CE02435; WP:CE29548; XJ888; YT45_CAEEL
B0495.4 B0495.4 P W All gene names: nhx-2; B0495.4; 2H982; CE29549; NM_063213; WBGene00003730; WP:CE29549 WormBase description: nhx-2 encodes a sodium/proton exchanger expressed in the apical membranes of intestinal cells; NHX-2 is required for normally high growth rates, and for propagation or maintenance of the germline, NHX-2 is thought to prevent intracellular acidification by catalysing the electroneutral exchange of extracellular sodium for an intracellular proton. WormBase CDS description: NA(+)/H(+) exchanger
B0495.9 B0495.9 P W All gene names: B0495.9; 2H998; CE01767; WBGene00015208; WP:CE01767; YP69_CAEEL
C02A12.4 C02A12.4 P W All gene names: lys-7; C02A12.4; 5D960; CE07828; NM_071571; WBGene00003096; WP:CE07828 WormBase description: lys-7 encodes an enzyme homologous to an antimicrobial lysozyme encoded by the LYS4 gene of the protozoan parasite Entamoeba histolytica; by homology, LYS-7 is predicted to function as an antimicrobial enzyme that hydrolyzes the 1,4-beta-linkages between N-acetyl-D-glucosamine and N-acetylmuramic acid in peptidoglycan heteropolymers of prokaryotic cell walls; in C. elegans, lys-7 expression is significantly upregulated in response to infection with the Gram-negative bacterium Serratia marcescens, indicating that LYS-7 likely plays a role in the innate immune response; constitutive expression of lys-7 mRNA is detected in the intestine and the intestinal valve cells.
C03B1.12 C03B1.12 P W All gene names: lmp-1; C03B1.12; C03B1.12.1; C03B1.12.2; CE03912; LMP1_CAEEL; NM_076671; WBGene00003053; WP:CE03912; XG996 WormBase description: lmp-1 encodes a protein with similarity to vertebrate lysosome-associated membrane proteins CD68, and appears to be the only protein in C. elegans that has a GYXX (phi) vertebrate lysosomal targeting sequence at its carboxy terminus; localized to the periphery of a large population of membrane bound organelles (granules) seen throughout the early embryos and restricted to the cells of the intestine during later stages.
C04F6.1 C04F6.1 P W All gene names: vit-5; C04F6.1; CE03921; NM_076188; VIT5_CAEEL; WBGene00006929; WP:CE03921; XE27 WormBase description: vit-5 encodes a vitellogenin, a lipid-binding protein precursor related to vertebrate vitellogenins and mammalian ApoB-100, a core LDL particle constituent; by homology, VIT-5 is predicted to function as a lipid transport protein; loss of vit-5 activity via large-scale RNA-mediated interference (RNAi) screens indicates that VIT-5 is required for embryogenesis and normal rates of postembryonic growth; VIT-5 is a major yolk component and is expressed exclusively in the adult hermaphrodite intestine from which it is secreted into the pseudocoelomic space and taken up by oocytes.
C05D11.10 C05D11.10 P W All gene names: C05D11.10; 3H520; CE01129; MRPS17; WBGene00015487; WP:CE01129; YPDA_CAEEL
C05D11.3 C05D11.3 P W All gene names: tag-170; C05D11.3; 3H521; CE01133; TXND9_CAEEL; WBGene00006515; WBGene00015482; WP:CE01133
C05D11.5 C05D11.5 P W All gene names: C05D11.5; 3H496; CE01135; WBGene00015483; WP:CE01135; YPD5_CAEEL
C06G1.4 C06G1.4 P W All gene names: ain-1; C06G1.4; C06G1.4.1; C06G1.4.2; CE03967; WBGene00015547; WP:CE03967; XR231
C07B5.2 C07B5.2 P W All gene names: C07B5.2; CE00892; WBGene00007407; WP:CE00892; XK134
C07D10.2 C07D10.2 P W All gene names: bath-44; C07D10.2; C07D10.2b.1; C07D10.2b.2; 2H687; CE27057; CE29072; Q95QX2_CAEEL; WBGene00015567; WP:CE27057; WP:CE29072 WormBase description: The C07D10.2 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis.
C09B8.6 C09B8.6 P W All gene names: hsp-25; C09B8.6; C09B8.6c.1; C09B8.6c.2; C09B8.6c.3; C09B8.6c.4; CE02466; CE33558; CE37953; Q17849_CAEEL; WBGene00002023; WP:CE02466; WP:CE33558; WP:CE37953; XG654 WormBase description: Small heat shock protein
C09F12.1 C09F12.1 P W All gene names: clc-1; C09F12.1; CE08040; NM_077446; WBGene00000522; WP:CE08040; XL667 WormBase description: clc-1 encodes a claudin homolog, closely similar to CLC-2, that is required for normal cohesion of apical junctions in epithelia; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water; CLC-1 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the pharynx to dyes; clc-1 is expressed in spermatheca, pharynx, intestine, hypodermis, the excretory-secretory system, and the cell-cell junctions of the vulva; in pharyngeal cells, CLC-1 colocalizes with AJM-1 in long thin lines, parallel to the pharyngeal axis and lining the lumenal surface, that appear to correspond with apical intercellular junctions.
C09F5.2 C09F5.2 P W All gene names: C09F5.2; 3B271; CE01774; ORAI_CAEEL; WBGene00015648; WP:CE01774
C13B9.4 C13B9.4 P W All gene names: C13B9.4; C13B9.4a.1; C13B9.4a.2; C13B9.4b.1; C13B9.4b.2; C13B9.4c.1; C13B9.4c.2; 3H724; CE30860; CE37087; CE37088; SEB1_CAEEL; WBGene00015735; WP:CE30860; WP:CE37087; WP:CE37088 WormBase description: C13B9.4 is orthologous to the human gene CALCITONIN RECEPTOR (CALCR; OMIM:114131), which when mutated leads to disease.
C13C4.5 C13C4.5 P W All gene names: C13C4.5; C13C4.5.1; C13C4.5.2; 5M597; CE08130; WBGene00007549; WP:CE08130 WormBase description: sugar transporter
C14C10.5 C14C10.5 P W All gene names: C14C10.5; 5N87; CE05284; WBGene00007588; WP:CE05284 WormBase description: Human mRNA (KIAA0077) product like
C16A3.10 C16A3.10 P W All gene names: C16A3.10; C16A3.10a.1; C16A3.10a.2; C16A3.10c.1; C16A3.10c.2; C16A3.10c.3; 3H484; CE04010; CE30604; CE37708; OAT_CAEEL; WBGene00015814; WP:CE04010; WP:CE30604; WP:CE37708 WormBase description: The C16A3.10 gene encodes a homolog of the human gene OAT (OMIM:258870), which when mutated leads to ornithinemia and gyrate atrophy.
C17E4.5 C17E4.5 P W All gene names: pab-3; C17E4.5; 1J998; CE08254; NM_060103; Q93233_CAEEL; WBGene00003904; WP:CE08254 WormBase description: pab-3 is orthologous to human PABPN1 (OMIM:602279, mutated in oculopharyngeal muscular dystrophy). WormBase CDS description: RNA binding protein (RNP like)
C17G10.1 C17G10.1 P W All gene names: C17G10.1; C17G10.1.1; C17G10.1.2; 2F887; CE01785; WBGene00015915; WP:CE01785
C17G10.5 C17G10.5 P W All gene names: lys-8; C17G10.5; 2F877; CE06846; NM_062682; Q09975_CAEEL; WBGene00003097; WP:CE06846
C18A3.6 C18A3.6 P W All gene names: rab-3; rbl-3; C18A3.6; C18A3.6b.1; C18A3.6b.2; 2G12; CE20518; CE23555; RAB3/A; RAB3_CAEEL; WBGene00004267; WP:CE20518; WP:CE23555; rab3 WormBase description: rab-3 encodes a rab3 homolog, a member of the Ras GTPase superfamily, and affects sensitivity to aldicarb and the distribution of synaptic vesicle populations and thereby affects synaptic transmission, track amplitude and speed of movement, chemotaxis to isoamyl alcohol, affects pharyngeal pump durations, and may only slightly affect male mating behavior; requires aex-3 for localization to synapse-rich regions in axons and it is expressed in most or all neurons. WormBase CDS description: synaptic vesicle-associated GTP-binding protein
C18G1.5 C18G1.5 P W All gene names: hil-4; C18G1.5; C18G1.5.1; C18G1.5.2; H1.4; 5F233; CE17421; H14_CAEEL; NM_071876; WBGene00001855; WP:CE17421 WormBase description: histone H1
C24A11.8 C24A11.8 P W All gene names: frm-4; C24A11.8; 1F972; CE19698; CE27724; NM_059185; NM_059186; WBGene00001491; WP:CE19698; WP:CE27724 WormBase description: frm-4 encodes a predicted transmembrane protein that contains an N-terminal FERM (Band 4.1-ezrin-radixin-moesin) domain; by homology, FRM-4 is predicted to function as a membrane-cytoskeleton linker protein that plays a role in cell adhesion, migration, or organization of cell surface structures; however, as loss of frm-4 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of FRM-4 in C. elegans development and/or behavior is not yet known.
C25G4.10 C25G4.10 P W All gene names: C25G4.10; 4N233; CE28206; WBGene00007736; WP:CE28206; YPG43_CAEEL WormBase description: fibronectin
C26F1.10 C26F1.10 P W All gene names: flp-21; C26F1.10; C26F1.10.1; C26F1.10.2; 5I273; CE30733; NM_072610; WBGene00001464; WP:CE30733 WormBase description: flp-21 encodes a single FMRFamide-related neuropeptide (FaRP) that serves as a ligand for NPR-1, a G protein-coupled receptor that regulates social versus solitary feeding behavior in several Caenorhabditis species; genetic analysis suggests that FLP-21 acts through NPR-1 to inhibit social feeding behavior; FLP-21 is expressed in the ADL, ASE and ASH sensory neurons, the URA motor neurons, the MC, M2 and M4 pharyngeal neurons, and the intestine; flp-21 encodes the only FMRFamide-related neuropeptide (FaRP) encoded by the C. elegans genome that activates both the social (215F) and the solitary (215V) forms of NPR-1 in both Xenopus oocytes and pharyngeal assays.
C26F1.5 C26F1.5 P W All gene names: grl-10; C26F1.5; 5I255; CE06879; NM_072604; WBGene00001719; WP:CE06879 WormBase description: grl-10 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
C27B7.1 C27B7.1 P W All gene names: spr-2; C27B7.1; 4J657; CE03030; CE27804; NM_069142; SPR2_CAEEL; WBGene00005007; WP:CE03030; WP:CE27804 WormBase description: spr-2 encodes the C. elegans ortholog of the Drosophila and mammalian SET proteins (OMIM:600960, translocation breakpoint in human SET is associated with acute myeloid leukemia); SPR-2 is predicted to be a member of the SET protein complex that functions in chromatin remodeling, DNA repair, and transcriptional regulation; in C. elegans, SPR-2 may function to regulate the activity and/or levels of the presenilin proteins encoded by sel-12 and hop-1, as mutations in spr-2 suppress mutations in sel-12 in a hop-1-dependent manner; spr-2 is detected in the nuclei of all cells at several developmental stages, including the L3 larval stage.
C27D6.4 C27D6.4 P W All gene names: C27D6.4; C27D6.4b.1; C27D6.4b.2; 2F468; CE32146; CE32147; CE32148; Q09636_CAEEL; WBGene00016162; WP:CE32146; WP:CE32147; WP:CE32148 WormBase description: BZIP protein
C27H5.3 C27H5.3 P W All gene names: C27H5.3; C27H5.3.1; C27H5.3.2; C27H5.3.3; 2H445; CE27099; WBGene00016173; WP:CE27099 WormBase description: Probable RNA binding protein
C29F7.3 C29F7.3 P W All gene names: C29F7.3; CE08444; WBGene00007812; WP:CE08444; XO38 WormBase description: uridylate kinase
C29F9.7 C29F9.7 P W All gene names: pat-4; C29F9.7; C29F9.7.1; C29F9.7.2; 3A708; CE19706; NM_064738; Q9TZC4_CAEEL; WBGene00003931; WP:CE19706 WormBase description: The pat-4 gene encodes a serine/threonine kinase orthologous to human integrin-linked kinase (ILK, OMIM:602366) and is required for formation of integrin-mediated muscle cell attachments during embryogenesis; PAT-4 probably functions as an adaptor molecule and localizes to dense bodies and M lines; PAT-4 forms a ternary complex with PAT-6/actopaxin and UNC-112, and requires UNC-112, UNC-52/perlecan, PAT-2/alpha integrin, and PAT-3/beta integrin for proper localization to newly forming integrin adhesion complexes. WormBase CDS description: integrin-linked kinase
C30C11.2 C30C11.2 P W All gene names: rpn-3; C30C11.2; C30C11.2.1; C30C11.2.2; 3J537; CE00101; NM_066468; PSMD3_CAEEL; WBGene00004460; WP:CE00101 WormBase description: Diphenol oxidase A2
C32D5.2 C32D5.2 P W All gene names: sma-6; C32D5.2; 2G617; CE01842; NM_062870; SMA6_CAEEL; WBGene00004860; WP:CE01842 WormBase description: sma-6 encodes a serine/threonine protein kinase that is orthologous to type I TGF-beta receptors; sma-6 activity is required for regulating body length and for proper development of the male tail; sma-6 expression first begins at the 1.5-fold stage of embryogenesis and continues through adulthood; sma-6 is expressed in dorsal and ventral hypodermis, pharyngeal muscle, and the intestine; expression in the hypodermis is necessary and sufficient for body length regulation. WormBase CDS description: Activin receptor
C32D5.9 C32D5.9 P W All gene names: lgg-1; C32D5.9; C32D5.9.1; C32D5.9.2; 2G636; CE01849; LGG1_CAEEL; NM_062876; WBGene00002980; WP:CE01849
C32E8.9 C32E8.9 P W All gene names: C32E8.9; 1E364; CE29693; WBGene00016325; WP:CE29693
C33D3.1 C33D3.1 P W All gene names: elt-2; C33D3.1; CE31430; ELT2_CAEEL; GATA; NM_077354; WBGene00001250; WP:CE31430; XL101 WormBase description: elt-2 encodes a GATA-type transcription factor most similar to the vertebrate GATA4-6 transcription factors required for cardiac and endoderm development (OMIM:601656, 600576); in C. elegans, ELT-2 is required redundantly with ELT-7 for initiating and maintaining terminal differentiation of the intestine; ELT-2 is expressed solely in the intestine, beginning embryonically at the 2E-cell stage and continuing in all intestinal cells throughout the life of the animal; in the regulatory hierarchy controlling endoderm development, ELT-2 lies downstream of the maternal regulators SKN-1 and POP-1 and the embryonic GATA factors MED-1/-2, and END-1/-3; in turn, ELT-2, along with ELT-7, likely regulates transcription of a number of intestine-specific terminal differentiation genes such as ges-1, ifb-2, pha-4, and the stress-induced mtl-2; ELT-2 also positively autoregulates, presumably to ensure maintenance of intestinal differentiation WormBase CDS description: zinc finger protein (GATA type)
C34G6.4 C34G6.4 P W All gene names: pgp-2; C34G6.4; 1G471; CE29212; NM_059306; WBGene00003996; WP:CE29212 WormBase description: pgp-2 encodes a member of the ABC transporter family with highest similarity to the vertebrate MDR (multidrug resistance) family, and is orthologous to human MDR1 (ABCB1; OMIM:171050, mutated in Crohn disease); PGP-2 is expressed at lower levels during the embryonic stages with higher expression later in development. WormBase CDS description: abc transporter
C35D10.12 C35D10.12 P W All gene names: C35D10.12; 3F962; CE01193; WBGene00016448; WP:CE01193
C35D10.14 C35D10.14 P W All gene names: clec-5; C35D10.14; 3F972; CE27828; WBGene00016450; WP:CE27828 WormBase description: 7TM chemoreceptor, clec family
C35D10.2 C35D10.2 P W All gene names: C35D10.2; 3F961; CE01196; Q18488_CAEEL; WBGene00016440; WP:CE01196
C36A4.9 C36A4.9 P W All gene names: C36A4.9; C36A4.9a.1; C36A4.9a.2; C36A4.9a.3; 3E955; CE03076; CE37209; WBGene00007969; WP:CE03076; WP:CE37209 WormBase description: acetyl-coenzyme A synthetase
C37E2.5 C37E2.5 P W All gene names: ceh-37; C37E2.5; CE08624; HM37_CAEEL; NM_077965; WBGene00000458; WP:CE08624; XO816 WormBase description: ceh-37 encodes one of three C. elegans proteins with an OTX-like homeodomain; however, CEH-37 lacks other domains found in OTX proteins, and the CEH-37 homeodomain is predicted to resemble the Myb domain of telomere-binding proteins; CEH-37 binds the telomeric sequence 'TTAGGC' if it is repeated at least 1.5 times, and is mainly localized to the telomere in vivo; ceh-37 mutants have a weak increase in chromosomal nondisjunction; CEH-37 is involved in specifying some aspects of the AWB olfactory neuron fate, such as expression of an AWB-specific odorant receptor and a LIM-class homeodomain protein, LIM-4; CEH-37 is expressed broadly in the early embryo, while in larvae and adults it is expressed solely in the excretory cell. WormBase CDS description: Homeobox domain
C39F7.1 C39F7.1 P W All gene names: C39F7.1; 5B741; CE16904; WBGene00016538; WP:CE16904
C39F7.4 C39F7.4 P W All gene names: rab-1; C39F7.4; C39F7.4.1; C39F7.4.2; 5B742; CE16905; NM_070996; WBGene00004266; WP:CE16905 WormBase description: rab-1 encodes an ortholog of the small Ras-like GTPase Rab1; by homology, RAB-1 is predicted to play a role in intracellular vesicle trafficking, and consistent with this broad role, large-scale RNAi screens indicate that rab-1 activity is required for fertility, movement, and survival; in yeast two-hybrid assays, RAB-1 interacts with TIR-1, a C. elegans SARM ortholog that is required for innate immunity; RNAi studies suggest that RAB-1 and TIR-1 likely function in a pathway that controls expression of antimicrobial peptides such as NLP-29 and NLP-31; rab-1 also appears to play a role in regulating polyglutamine protein aggregation, as rab-1(RNAi) animals show premature accumulation of protein aggregates; in situ hybridization studies indicate that rab-1 is broadly expressed, with elevated levels apparent in the germline. WormBase CDS description: RAS-related protein
C44C1.2 C44C1.2 P W All gene names: C44C1.2; CE30126; WBGene00016642; WP:CE30126; XB577
C46C11.2 C46C11.2 P W All gene names: C46C11.2; CE39005; CE39006; WBGene00016705; WP:CE39005; WP:CE39006; XF253
C47D2.2 C47D2.2 P W All gene names: cdd-1; tag-17; C47D2.2; CE06962; NM_076983; WBGene00000391; WP:CE06962; XI826 WormBase description: cdd-1 encodes a cytidine deaminase that contains a zinc-binding region; expressed in the intestine. WormBase CDS description: cytidine deaminase
C47E12.8 C47E12.8 P W All gene names: CeCRMP/DHP-2; dhp-2; C47E12.8; 4K745; CE05452; DHP2_CAEEL; NM_069396; WBGene00000964; WP:CE05452 WormBase description: The dhp-2 gene encodes an ortholog of the human gene DIHYDROPYRIMIDINASE (DPYS), which when mutated leads to dihydropyrimidinuria (OMIM:222748). WormBase CDS description: Ulip like protein
C49C3.5 C49C3.5 P W All gene names: C49C3.5; 4S273; CE19744; WBGene00008195; WP:CE19744 WormBase description: Homeobox domain
C49C8.5 C49C8.5 P W All gene names: C49C8.5; C49C8.5.1; C49C8.5.2; 4J414; CE31453; WBGene00016769; WP:CE31453
C52B9.6 C52B9.6 P W All gene names: twk-28; C52B9.6; CE35710; NM_076331; WBGene00006680; WP:CE35710; XE894
C52E4.1 C52E4.1 P W All gene names: cpr-1; gcp-1; C52E4.1; 5M457; CE31896; CPR1_CAEEL; CPROT/1; NM_073601; WBGene00000781; WP:CE31896 WormBase description: cpr-1 encodes a cysteine protease of the cathepsin B-like cysteine protease family; cpr-1 appears to be required for embryogenesis; cpr-1 is specifically expressed in the gut of all stages except the embryo and around developing embryos in the gonad; expression of cpr-1 is regulated by three promoter GATA motifs. WormBase CDS description: cathepsin-like cysteine protease
C52E4.2 C52E4.2 P W All gene names: mif-2; C52E4.2; C52E4.2.1; C52E4.2.2; 5M458; CE08944; MIF2_CAEEL; NM_073602; WBGene00003235; WP:CE08944 WormBase description: macrophage migration inhibitory factor like protein
C53A5.3 C53A5.3 P W All gene names: gon-10; hda-1; C53A5.3; C53A5.3.1; C53A5.3.2; 5P7; CE08952; HDA1_CAEEL; NM_074198; WBGene00001834; WP:CE08952 WormBase description: The hda-1 gene encodes a histone deacetylase 1, similar to histone deacetylases RPD3 from yeast and fly; maternal and zygotic expression of hda-1 is required for embryonic viability, and zygotic expression of hda-1 is also required for gonadogenesis and vulval development. WormBase CDS description: Yeast RPD3 protein like
C53B4.7 C53B4.7 P W All gene names: C53B4.7; 4J753; CE27116; CE27117; GMD1_CAEEL; WBGene00008276; WP:CE27116; WP:CE27117 WormBase description: bre-1 is required for Cry5B toxicity.
C54H2.5 C54H2.5 P W All gene names: SURF-4; sft-4; C54H2.5; CE06987; NM_076569; SURF4_CAEEL; WBGene00004788; WP:CE06987; XG398 WormBase description: sft-4 encodes a member of the SURF family highly conserved with the mouse Surf-4 gene, and conservation includes an encoded dilysine motif that is implicated in endoplasmic reticulum localization of the mouse protein.
C56C10.8 C56C10.8 P W All gene names: icd-1; C56C10.8; C56C10.8.1; C56C10.8.2; 2G878; BTF3_CAEEL; CE02573; NM_062935; WBGene00002045; WP:CE02573 WormBase description: Transcription factor BTF3 (human)
CD4.2 CD4.2 P W All gene names: crn-2; CD4.2; 5G75; CE16950; NM_072075; WBGene00000795; WP:CE16950 WormBase description: crn-2 encodes a cell death-related nuclease, homologous to the magnesium-dependant TatD nuclease of E. coli; CRN-2 is required for normal levels of DNA degradation during apoptosis; crn-2(RNAi) 1.5-fold stage embryos display TUNEL labelling of nuclei that is five-fold higher than that seen in untreated N2 animals; CRN-2 promotes both DNA degradation and cell corpse engulfment, in a partially redundant pathway that includes CRN-3 but is parallel to CPS-6; CRN-2 is predicted to be mitochondrial.
D2007.5 D2007.5 P W All gene names: D2007.5; D2007.5.1; D2007.5.2; 3J246; CE00130; WBGene00017045; WP:CE00130; YLM5_CAEEL
D2013.10 D2013.10 P W All gene names: tag-175; D2013.10; 2J613; CE17622; WBGene00006520; WBGene00008406; WP:CE17622
E03H4.13 E03H4.13 P W All gene names: nhr-89; E03H4.13; 1N28; CE09139; NHR89_CAEEL; NM_060754; WBGene00003679; WP:CE09139 WormBase description: Zinc finger, C4 type (two domains)
F01F1.12 F01F1.12 P W All gene names: F01F1.12; F01F1.12a.1; F01F1.12a.2; F01F1.12a.3; F01F1.12b.1; F01F1.12b.2; 3G964; ALF2_CAEEL; CE01225; CE30646; WBGene00017166; WP:CE01225; WP:CE30646 WormBase description: The F01F1.12 gene encodes a homolog of the human gene ADHUB, which when mutated leads to fructosemia (OMIM:229600).
F01F1.2 F01F1.2 P W All gene names: F01F1.2; 3G969; CE26886; WBGene00017159; WP:CE26886
F01G10.1 F01G10.1 P W All gene names: F01G10.1; F01G10.1.1; F01G10.1.2; 4L9; CE09163; WBGene00008506; WP:CE09163 WormBase description: The F01G10.1 gene encodes an ortholog of the human gene TRANSKETOLASE (TKT; OMIM:606781), which when mutated leads to Wernicke-Korsakoff syndrome (OMIM:277730). WormBase CDS description: transketolase
F01G4.1 F01G4.1 P W All gene names: psa-4; F01G4.1; F01G4.1.1; F01G4.1.2; 4L895; CE05553; NM_069681; WBGene00004204; WP:CE05553 WormBase description: The psa-4 (phasmid socket absent) gene encodes an ortholog of SWI2/SNF2, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; psa-4 is probably required during mitosis of the T cells for asymmetric cell division. WormBase CDS description: SNF2alpha like
F01G4.6 F01G4.6 P W All gene names: F01G4.6; F01G4.6.1; F01G4.6.2; F01G4.6.3; F01G4.6.4; 4L912; CE09162; MPCP_CAEEL; WBGene00008505; WP:CE09162 WormBase description: phosphate carrier protein precursor
F02A9.3 F02A9.3 P W All gene names: far-2; pes-3; F02A9.3; F02A9.3.1; F02A9.3.2; 3K171; CE00134; FAR2_CAEEL; NM_066610; WBGene00001386; WP:CE00134 WormBase description: far-2 encodes a protein similar to a class of secreted fatty acid and retinol-binding proteins expressed in parasitic nematodes and secreted in the surrounding tissues of the host; expressed in body wall muscle and vulval cells of adult hermaphrodites, and transcript levels progressively increase during development.
F07A11.4 F07A11.4 P W All gene names: F07A11.4; 2L901; CE03146; WBGene00008547; WP:CE03146 WormBase description: ubiquitin carboxyl-terminal hydrolase
F08B6.2 F08B6.2 P W All gene names: gpc-2; F08B6.2; F08B6.2.1; F08B6.2.2; F08B6.2.3; 1H335; CE20656; NM_059534; WBGene00001682; WP:CE20656 WormBase description: gpc-2 encodes one of two C. elegans heterotrimeric G protein gamma subunits; gpc-2 is required, along with its partner GPB-1, a G protein beta subunit, for proper mitotic spindle positioning and orientation during early embryonic cell divisions; to date, GPC-2 expression has been reported in electrically excitable cells (all neurons and muscles).
F10B5.7 F10B5.7 P W All gene names: rrf-3; F10B5.7; 2I457; CE02178; NM_063312; WBGene00004510; WP:CE02178 WormBase description: rrf-3 encodes an RNA-directed RNA polymerase (RdRP) homolog that inhibits somatic RNAi, and thus promotes activity of repeated genes (e.g., multicopy transgenic arrays); the effect of RRF-3 on RNAi is opposite to that of RRF-1 (which stimulates somatic RNAi), which might arise from competition by RRF-3 with RRF-1 or EGO-1 in RNAi formation; rrf-3(allele) or rrf-3(allele2) mutants are hypersensitive to somatic RNAi, and conversely suppress the activity of an integrated rol6 (su1006) transgene.
F11E6.5 F11E6.5 P W All gene names: elo-2; F11E6.5; 4S410; CE19785; NM_070713; WBGene00001240; WP:CE19785 WormBase description: The elo-2 gene encodes a palmitic acid elongase, homologous to polyunsaturated fatty acid (PUFA) elongases such as ELO-1, that is required for normally rapid growth, normally large body size, fertility, and for the quantitative regulation of the ultradian defecation rhythm; the joint action of ELO-2 with ELO-1 is strongly required for 20-carbon PUFA production and for general viability; elo-2 is most strongly expressed in intestinal cells, as well as other tissues such as the ventral nerve cord, pharyngeal muscles, uterus, and tail. WormBase CDS description: GNS1/SUR4 family
F11H8.4 F11H8.4 P W All gene names: cyk-1; F11H8.4; 3I114; CE36535; CE36536; NM_171180; NM_171880; WBGene00000872; WP:CE36535; WP:CE36536 WormBase description: The cyk-1 gene encodes a homolog of Drosophila diaphanous and human DIAPH1. WormBase CDS description: required for a late step in embryonic cytokinesis
F13G3.9 F13G3.9 P W All gene names: mif-3; F13G3.9; 1H890; CE09371; MIF3_CAEEL; NM_059668; WBGene00003236; WP:CE09371 WormBase description: macrophage migratory inhibitory factor MIF like
F15G9.1 F15G9.1 P W All gene names: F15G9.1; CE01549; CE23660; CE32382; WBGene00008865; WP:CE01549; WP:CE23660; WP:CE32382; XK325; YSI1_CAEEL
F20D1.10 F20D1.10 P W All gene names: tag-299; F20D1.10; F20D1.10.1; F20D1.10.2; CE23677; WBGene00008980; WP:CE23677; XP599
F21G4.2 F21G4.2 P W All gene names: mrp-4; F21G4.2; CE09548; NM_077257; WBGene00003410; WP:CE09548; XK507 WormBase description: The mrp-4 gene encodes a homolog of human CFTR, which when mutated leads to cystic fibrosis (OMIM:219700). WormBase CDS description: multidrug resistance-associated protein
F22B5.1 F22B5.1 P W All gene names: arf-2; evl-20; F22B5.1; 2I735; ARF/2; ARFM_CAEEL; CE27425; NM_063378; WBGene00001358; WP:CE27425 WormBase description: evl-20 encodes a functional ortholog of human ADP-ribosylation factor-like protein 2 (ARL2; OMIM:601175), with evl-20(ar103) mutants being rescued by transgenic human ARL2 but not ARL1 or ARL3-7; EVL-20 is required for cortical microtubule formation during cytokinesis and morphogenesis; EVL-20 is required for vulval, gonadal, and male tail development, as well as for embryonic mitosis, hypodermal enclosure, and elongation; EVL-20 is expressed in migrating hypodermal embryonic cells, larval vulval and somatic gonad cells, larval and adult neurons, and adult male proctodeal cells, being subcellularly associated with both the cell cortex and astral microtubules. WormBase CDS description: GTP-binding ADP-ribosylation factor
F22F1.1 F22F1.1 P W All gene names: hil-3; F22F1.1; H1.3; CE04443; H13_CAEEL; NM_076974; WBGene00001854; WP:CE04443; XI779 WormBase description: histone h1
F23F1.8 F23F1.8 P W All gene names: rpt-4; F23F1.8; F23F1.8b.1; F23F1.8b.2; F23F1.8b.3; 2A332; CE09608; CE29280; PRS10_CAEEL; WBGene00004504; WP:CE09608; WP:CE29280 WormBase description: rpt-4 encodes a predicted ATPase subunit of the 19S regulatory complex of the proteasome that affects body morphology, embryonic viability, growth, movement, and fertility; interacts with itself in yeast two-hybrid assays.
F23H11.5 F23H11.5 P W All gene names: F23H11.5; F23H11.5.1; F23H11.5.2; F23H11.5.3; 3B528; CE09613; WBGene00000263; WP:CE09613 WormBase description: The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway.
F25H2.5 F25H2.5 P W All gene names: F25H2.5; F25H2.5.1; F25H2.5.2; F25H2.5.3; 1L130; CE09650; WBGene00009119; WP:CE09650 WormBase description: nucleoside diphosphate kinase
F26E4.12 F26E4.12 P W All gene names: F26E4.12; 1K359; CE09696; GPX1_CAEEL; WBGene00009165; WP:CE09696 WormBase description: glutathione peroxidase
F26F4.6 F26F4.6 P W All gene names: F26F4.6; 3F980; CE29290; WBGene00017828; WP:CE29290
F26H11.5 F26H11.5 P W All gene names: exl-1; F26H11.5; 2O698; CE24922; EXL1_CAEEL; NM_064599; WBGene00001371; WP:CE24922
F27D4.1 F27D4.1 P W All gene names: F27D4.1; F27D4.1.1; F27D4.1.2; 1I279; CE24926; ETFA_CAEEL; WBGene00009187; WP:CE24926 WormBase description: The F27D4.1 gene encodes an ortholog of the human gene ELECTRON-TRANSFER-FLAVOPROTEIN, ALPHA POLYPEPTIDE (ETFA), which when mutated leads to glutaricaciduria type IIA (OMIM:231680). WormBase CDS description: electron transfer flavoprotein alpha-subunit
F28B12.2 F28B12.2 P W All gene names: egl-44; F28B12.2; F28B12.2e.1; F28B12.2e.2; F28B12.2e.3; F28B12.2f.1; F28B12.2f.2; 2G229; CE27143; CE33378; CE33379; CE33380; CE33381; CE33382; EGL44_CAEEL; NM_062785; NM_171007; NM_171850; NM_182104; NM_182105; NM_182106; WBGene00001208; WP:CE27143; WP:CE33378; WP:CE33379; WP:CE33380; WP:CE33381; WP:CE33382 WormBase description: The egl-44 gene encodes a putative transcription regulatory protein of 471 amino acids similar to vertebrate transcription enhancer factor (TEF) proteins.
F28D1.7 F28D1.7 P W All gene names: rps-23; F28D1.7; F28D1.7.1; F28D1.7.2; 4N154; CE05747; NM_069964; RS23_CAEEL; WBGene00004492; WP:CE05747 WormBase description: rps-23 encodes a small ribosomal subunit S23 protein; by homology, RPS-23 is predicted to function in protein biosynthesis; in C. elegans, RPS-23 activity is required for germline development, vulval morphogenesis, and the overall health of the animal. WormBase CDS description: ribosomal protein S23
F31C3.1 F31C3.1 P W All gene names: cyn-5; cyp-5; F31C3.1; F31C3.1.1; F31C3.1.2; 1P632; CE17730; CYP5_CAEEL; NM_061223; WBGene00000881; WP:CE17730 WormBase description: cyp-5 encodes a cyclophilin that is functional in vitro and is predicted to be a secreted protein that is structurally most similar to human cyclophilin B; expressed in the intestine. WormBase CDS description: cyclophillin
F31D4.1 F31D4.1 P W All gene names: F31D4.1; 5V311; CE31921; WBGene00009289; WP:CE31921
F32D8.6 F32D8.6 P W All gene names: emo-1; oar-1; F32D8.6; F32D8.6.1; F32D8.6.2; 5L376; CE05785; NM_073377; SC61G_CAEEL; WBGene00001303; WP:CE05785 WormBase description: emo-1 encodes an ortholog of S. cerevisiae Sec61p gamma subunit, which is required for translocation of secreted and membrane proteins into the endoplasmic reticulum; EMO-1 is required for oogenesis and ovulation. WormBase CDS description: protein transport protein SEC61 gamma subunit
F33A8.5 F33A8.5 P W All gene names: F33A8.5; F33A8.5.1; F33A8.5.2; 2L340; CE17757; DHSD_CAEEL; WBGene00009353; WP:CE17757 WormBase description: F33A8.5 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT D, INTEGRAL MEMBRANE PROTEIN (SDHD; OMIM:602690), which when mutated leads to disease.
F33D4.1 F33D4.1 P W All gene names: nhr-8; F33D4.1; 4I477; CE33927; CE33928; NHR8_CAEEL; NM_171382; WBGene00003607; WP:CE33927; WP:CE33928 WormBase description: The nhr-8 gene encodes a nuclear hormone receptor homolog; nhr-8(ok186) mutants have abnormally low resistance to the toxins colchicine and chloroquine.
F35B12.7 F35B12.7 P W All gene names: nlp-24; F35B12.7; F35B12.7.1; F35B12.7.2; 5M97; CE37515; NM_073545; WBGene00003762; WP:CE37515
F35C5.6 F35C5.6 P W All gene names: clec-63; F35C5.6; F35C5.6.1; F35C5.6.2; 2N187; CE15947; WBGene00009394; WP:CE15947 WormBase description: Lectin C-type domain short and long forms, von Willebrand factor type A domain
F35C5.8 F35C5.8 P W All gene names: clec-65; F35C5.8; 2N193; CE15949; WBGene00009396; WP:CE15949 WormBase description: von Willebrand factor type A domain
F35C8.6 F35C8.6 P W All gene names: pfn-2; F35C8.6; CE39098; NM_076509; PROF2_CAEEL; WBGene00003990; WP:CE39098; XF972
F35H8.5 F35H8.5 P W All gene names: elr-1; exc-7; F35H8.5; 2J871; CE00983; NM_063656; Q20084_CAEEL; WBGene00001368; WP:CE00983 WormBase description: exc-7 encodes an ELAV, an mRNA-binding protein homologous to Drosophila ELAV and human HuC/D (OMIM:603458, 168360, autoimmune antigens associated with paraneoplastic neurologic disorders); EXC-7 is required for formation of the tailspike and the excretory cell canals; exc-7 mutations enhance defects produced by mutations in exc-3, predicted to encode a peptidase, and sma-1, which encodes beta H-spectrin, a key component of the apical cytokeleton of polarized epithelial cells such as the excretory cell; in vitro, EXC-7 can bind the sma-1 mRNA 3' UTR, and thus is predicted to regulate SMA-1 expression in vivo; EXC-7 is expressed transiently in the excretory cell nucleus during mid-embryogenesis and during larval stages is detected in the pharynx, nerve ring, and nerve cord nuclei. WormBase CDS description: HUD
F36A2.8 F36A2.8 P W All gene names: F36A2.8; 1J389; CE32406; WBGene00009455; WP:CE32406 WormBase description: Drosophila sex-regulated protein janus like
F36F2.1 F36F2.1 P W All gene names: F36F2.1; 1J595; CE15975; WBGene00009475; WP:CE15975
F37C12.9 F37C12.9 P W All gene names: rps-14; F37C12.9; F37C12.9.1; F37C12.9.2; 3I268; CE00821; NM_066171; RS14_CAEEL; WBGene00004483; WP:CE00821 WormBase description: rps-14 encodes a small ribosomal subunit S14 protein; by homology, RPS-14 is predicted to function in protein biosynthesis; in C. elegans, RPS-14 activity is required for embryonic and germline development, as well as the overall health of the animal. WormBase CDS description: Ribosomal protein S14
F38A6.3 F38A6.3 P W All gene names: hif-1; F38A6.3; F38A6.3e.1; F38A6.3e.2; 5V253; CE18671; CE18672; CE32019; CE38181; CE38182; NM_075607; WBGene00001851; WP:CE18671; WP:CE18672; WP:CE32019; WP:CE38181; WP:CE38182 WormBase description: hif-1 encodes an ortholog of the mammalian hypoxia-induced factor HIF-1, and is required for survival in hypoxic environments (1% oxygen) that have no effect on wild-type C. elegans.
F39G3.1 F39G3.1 P W All gene names: ugt-61; F39G3.1; 5F221; CE30782; WBGene00018206; WP:CE30782 WormBase description: 7TM chemoreceptor, ugt family
F40E3.2 F40E3.2 P W All gene names: F40E3.2; 1D207; CE34307; WBGene00018230; WP:CE34307
F41D9.3 F41D9.3 P W All gene names: wrk-1; F41D9.3; F41D9.3b.1; F41D9.3b.2; CE30985; CE30986; CE30987; CE34015; CE37643; WBGene00006942; WP:CE30985; WP:CE30986; WP:CE30987; WP:CE34015; WP:CE37643; XJ6
F42D1.2 F42D1.2 P W All gene names: F42D1.2; F42D1.2.1; F42D1.2.2; CE10298; Q93703_CAEEL; WBGene00009628; WP:CE10298; XP411 WormBase description: tyrosine aminotransferase
F42E11.4 F42E11.4 P W All gene names: tni-1; F42E11.4; CE03311; NM_077505; TNNI1_CAEEL; WBGene00006584; WP:CE03311; XL994 WormBase description: tni-1 encodes a member of the troponin family that affects body morphology, locomotion, egg laying, and epithelial morphogenesis in a large-scale RNAi analysis. WormBase CDS description: troponin I
F42G9.2 F42G9.2 P W All gene names: cyn-6; cyp-6; F42G9.2; 3B391; CE01301; CYP6_CAEEL; NM_064856; WBGene00000882; WP:CE01301 WormBase description: cyp-6 encodes a cyclophilin most similar to human secreted cyclophilin type B isoforms that is functional when expressed in E. coli; it is expressed in the intestine.
F43C1.4 F43C1.4 P W All gene names: nhr-20; F43C1.4; 3F320; CE28025; NHR20_CAEEL; NM_065448; WBGene00003619; WP:CE28025 WormBase description: Zinc finger, C4 type (two domains)
F43D9.4 F43D9.4 P W All gene names: sec-1; sip-1; F43D9.4; F43D9.4.1; F43D9.4.2; 3L596; CE00994; NM_066915; SIP/1; SIP1_CAEEL; WBGene00004798; WP:CE00994 WormBase description: Heat shock hsp20 proteins
F43E2.8 F43E2.8 P W All gene names: hsp-4; F43E2.8; F43E2.8.1; F43E2.8.2; 2H640; CE07244; HSP7D_CAEEL; NM_063135; WBGene00002008; WP:CE07244 WormBase description: hsp-4 encodes a predicted homolog of the mammalian ER chaperone BiP that affects embryonic and larval viability; expression is most prominent in the spermatheca and transcription of hsp-4 is induced in the gut and in the hypodermis upon ER stress. WormBase CDS description: heat shock protein
F43G9.1 F43G9.1 P W All gene names: F43G9.1; F43G9.1.1; F43G9.1.2; 1J182; CE34018; IDH3A_CAEEL; WBGene00009664; WP:CE34018 WormBase description: isocitrate dehydrogenase
F43G9.3 F43G9.3 P W All gene names: F43G9.3; 1J190; CE10358; WBGene00009666; WP:CE10358 WormBase description: mitochondrial carrier protein
F44G3.6 F44G3.6 P W All gene names: skr-3; F44G3.6; F44G3.6.1; F44G3.6.2; 5Q603; CE16037; NM_074658; WBGene00004809; WP:CE16037 WormBase description: The skr-3 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-3(RNAi) animals are at least superficially normal.
F46A9.5 F46A9.5 P W All gene names: skr-1; F46A9.5; F46A9.5.1; F46A9.5.2; F46A9.5.3; 1K49; CE10580; NM_060112; Q93647_CAEEL; WBGene00004807; WP:CE10580 WormBase description: The skr-1 gene encodes a homolog of Skp1 in S. cerevisiae that is required for the restraint of cell proliferation, progression through the pachytene stage of meiosis, and the formation of bivalent chromosomes at diakinesis. WormBase CDS description: cyclin A/CDK2-associated protein P19 like
F46E10.9 F46E10.9 P W All gene names: dpy-11; F46E10.9; F46E10.9.1; F46E10.9.2; F46E10.9.3; F46E10.E; 5G992; CE20819; NM_072254; Q9UAV4_CAEEL; WBGene00001073; WP:CE20819 WormBase description: dpy-11 encodes a membrane- associated thioredoxin- like (TRX) protein that affects body shape and ray morphology; the TRX domain displays catalytic activity in vitro, and dpy-11 is expressed in cytoplasm of hypodermis. WormBase CDS description: thioredoxin
F46F2.3 F46F2.3 P W All gene names: F46F2.3; CE05880; WBGene00009787; WP:CE05880; XP878
F47B8.8 F47B8.8 P W All gene names: F47B8.8; 5O813; CE10646; WBGene00009809; WP:CE10646
F47D12.4 F47D12.4 P W All gene names: hmg-1.2; son-1; F47D12.4; 3H371; CE26923; CE28233; CE28234; HMG12_CAEEL; NM_065974; WBGene00001972; WP:CE26923; WP:CE28233; WP:CE28234
F48C11.3 F48C11.3 P W All gene names: nlp-3; F48C11.3; CE10752; NM_077786; WBGene00003741; WP:CE10752; XN796 WormBase description: nlp-3 encodes a neuropeptide-like protein of the GFxGF family with similarity to orcokinins, highly conserved peptides native to crustaceans that enhance hindgut contractions; NLP-3 is expressed in neurons in the head, pharynx, and vulva, and in the intestine; the precise role of NLP-3 in nervous system function and development is not yet clear.
F48E8.1 F48E8.1 P W All gene names: lon-1; F48E8.1; 3G567; CE01953; CE29046; CE30996; LON1_CAEEL; NM_065765; NM_065766; NM_171866; WBGene00003055; WP:CE01953; WP:CE29046; WP:CE30996 WormBase description: The lon-1 gene encodes a protein belonging to the PR-protein superfamily that is a target of DBL-1 (TGF-beta) signaling, and that regulates polyploidization and body length.
F49E12.9 F49E12.9 P W All gene names: F49E12.9; 2I679; CE03385; WBGene00009902; WP:CE03385 WormBase description: ERG-3 like protein
F49E8.4 F49E8.4 P W All gene names: cdd-2; F49E8.4; 4I312; CE10792; NM_068820; Q20628_CAEEL; WBGene00000392; WP:CE10792 WormBase description: A functional cytidine deaminase that affects morphology of embryos; it is expressed at all life cycle stages. WormBase CDS description: cytidine deaminase
F49E8.5 F49E8.5 P W All gene names: dif-1; F49E8.5; F49E8.5.1; F49E8.5.2; 4I316; CE28408; DIF1_CAEEL; NM_068822; WBGene00000996; WP:CE28408 WormBase description: dif-1 encodes a putative mitochondrial solute carrier, orthologous to human SLC25A20 (OMIM:212138, mutated in carnitine-acylcarnitine translocase deficiency) that is required for the maintenance of embryonic tissue differentiation and viability; expressed throughout development and in the intestinal cells and hypodermis of the embryo. WormBase CDS description: mitochondrial carrier family
F52E1.1 F52E1.1 P W All gene names: pos-1; F52E1.1; 5I895; CE04629; NM_072771; WBGene00004078; WP:CE04629 WormBase description: pos-1 encodes a CCCH-type zinc-finger protein; during embryogenesis, maternally provided POS-1 is essential for proper fate specification of germ cells, intestine, pharynx, and hypodermis; POS-1's role in cell fate specification is likely as a translational regulator, as POS-1 is required, in posterior blastomeres, for positive regulation of apx-1 mRNA translation and negative regulation of glp-1 mRNA translation via direct binding to the spatial control region (SCR) in the glp-1 mRNA 3' UTR; in regulating mRNA translation, POS-1 interacts with SPN-4, an RNP-type RNA binding protein, that may function to negatively regulate POS-1 activity; pos-1 mRNA is first detected in the gonads of L4 and adult animals, and is present uniformly in oocytes and newly fertilized embryos; during early embryonic divisions, pos-1 mRNA is present at higher levels in germline blastomeres until it disappears following the division of P4; POS-1 protein is first apparent at low levels in 1-cell embryos, with subsequent expression mirroring that of pos-1 mRNA: high levels in germline blastomeres until its disappearance after the P4 division; in the germline blastomeres P1, P2, P3, and P4, POS-1 colocalizes with cytoplasmic and perinuclear P granules. WormBase CDS description: zinc-finger protein
F52E1.13 F52E1.13 P W All gene names: F52E1.13; F52E1.13b.1; F52E1.13b.2; 5I896; CE33101; CE33102; CE33104; CE37651; P90882_CAEEL; WBGene00018700; WP:CE33101; WP:CE33102; WP:CE33104; WP:CE37651
F52E4.6 F52E4.6 P W All gene names: wrt-2; F52E4.6; CE07273; NM_076128; WBGene00006948; WP:CE07273; XD712 WormBase description: wrt-2 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a C-terminal region of low-complexity sequence; WRT-2 is expressed in seam cells and hypodermal syncytia; the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-2 is weakly required for normal molting; WRT-2 is also required for normal growth to full size and locomotion; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking; in two-hybrid assays, WRT-2 binds EYA-1, which may parallel the derepression of Drosophila eyes absent by HEDGEHOG.
F52H3.3 F52H3.3 P W All gene names: bath-38; F52H3.3; 2K334; BAT38_CAEEL; CE03399; WBGene00009945; WP:CE03399 WormBase description: BTB (also known as BR-C/Ttk) domain.
F53A2.4 F53A2.4 P W All gene names: nud-1; F53A2.4; 3O429; CE16096; NM_067348; WBGene00003829; WP:CE16096 WormBase description: nud-1 encodes the C. elegans ortholog of the Aspergillus nidulans nudC, which mediates nuclear migration along Aspergillus hyphae.
F53A9.10 F53A9.10 P W All gene names: tnt-2; F53A9.10; F53A9.10a.1; F53A9.10a.2; F53A9.10b.1; F53A9.10b.2; F53A9.10b.3; F53A9.10b.4; CE34313; CE34878; WBGene00006587; WP:CE34313; WP:CE34878; XJ340
F54C8.4 F54C8.4 P W All gene names: F54C8.4; 3K532; CE00190; PTP4_CAEEL; WBGene00010037; WP:CE00190 WormBase description: Protein-tyrosine phosphatase
F54C9.7 F54C9.7 P W All gene names: F54C9.7; 2I865; CE02257; WBGene00010043; WP:CE02257
F54D7.4 F54D7.4 P W All gene names: zig-7; F54D7.4; 1F360; CE33929; NM_059050; WBGene00006984; WP:CE33929
F54D8.3 F54D8.3 P W All gene names: alh-1; F54D8.3; F54D8.3a.1; F54D8.3a.2; F54D8.3b.1; F54D8.3b.2; F54D8.3b.3; 3G169; CE29809; CE32434; NM_065680; NM_181921; WBGene00000107; WP:CE29809; WP:CE32434 WormBase description: alh-1 is orthologous to the human gene ALDEHYDE DEHYDROGENASE 2, MITOCHONDRIAL (ALDH2; OMIM:100650), in which a polymorphism can lead to acute ethanol intolerance.
F54E7.7 F54E7.7 P W All gene names: rcn-1; F54E7.7; 3G772; CCPL_CAEEL; CE31002; DSCR1L; NM_065822; SC; WBGene00004321; WP:CE31002 WormBase description: rcn-1 encodes a calcipressin, which binds and inhibits calcineurin; RCN-1's orthologs include yeast Rcn1p and human DSCR1 (OMIM:602917; overexpressed in Down syndrome and Alzheimer disease); rcn-1 is expressed in hypodermal seam cells, various neurons, vulval epithelial and muscle cells, marginal pharyngeal cells, and in the male tail; rcn-1 transcription is regulated by TAX-6, and RCN-1 binds TAX-6 protein if free Ca[2+] is present; RCN-1 overexpression, like calcineurin deficiency, causes defects in body size, cuticle thickness, fertility, growth rate, and serotonin-resistance in egg-laying.
F55A12.7 F55A12.7 P W All gene names: apm-1; F55A12.7; 1F912; CE30145; NM_059171; WBGene00000150; WP:CE30145 WormBase description: The apm-1 gene encodes an adaptin: specifically, it encodes an ortholog of the mu1-II subunit of adaptor protein complex 1 (AP-1). WormBase CDS description: clathrin coat assembly protein complex 1 medium chain
F55G11.4 F55G11.4 P W All gene names: F55G11.4; 4N739; CE18750; WBGene00010124; WP:CE18750
F56C9.7 F56C9.7 P W All gene names: F56C9.7; F56C9.7.1; F56C9.7.2; 3I404; CE01326; WBGene00018951; WP:CE01326
F56E10.4 F56E10.4 P W All gene names: rps-27; F56E10.4; F56E10.4.1; F56E10.4.2; F56E10.4.3; F56E10.4.4; 5A582; CE19904; NM_070733; RS27_CAEEL; WBGene00004496; WP:CE19904 WormBase description: rps-27 encodes a small ribosomal subunit S27 protein. WormBase CDS description: ribosomal protein
F56F10.3 F56F10.3 P W All gene names: F56F10.3; CDO_CAEEL; CE28465; WBGene00018986; WP:CE28465; XB482 WormBase description: cytenine dioxygenase
F58B3.5 F58B3.5 P W All gene names: mrs-1; F58B3.5; 4M398; CE06007; NM_069795; SYMC_CAEEL; WBGene00003415; WP:CE06007 WormBase description: mrs-1 encodes a predicted cytoplasmic methionyl-tRNA synthetase (MetRS), a class I aminoacyl-tRNA synthetase that catalyzes the attachment of methionine to its cognate tRNA and is thus required for protein biosynthesis; MRS-1 is essential for embryogenesis and required also for a normal rate of postembryonic growth. WormBase CDS description: methionyl-tRNA synthetase
F58E10.4 F58E10.4 P W All gene names: aip-1; F58E10.4; 5O493; CE18786; NM_074078; WBGene00000097; WP:CE18786 WormBase description: aip-1 encodes an AN-1-like zinc finger-containing protein homologous to arsenite-inducible RNA-associated protein (AIRAP), conserved among C. elegans, Drosophila, and mammals; like AIRAP itself, AIP-1 protects cells from arsenite toxicity; AIP-1 is a predicted RNA binding protein that may function in ubiquitin-mediated proteolysis following aresenite treatment; AIP-1 does not appear to be essential for viability, but is expressed at high levels in hypodermal and intestinal cells following such treatment.
F58G1.4 F58G1.4 P W All gene names: F58G1.4; 2N223; CE17924; WBGene00010266; WP:CE17924
F59B8.2 F59B8.2 P W All gene names: F59B8.2; F59B8.2.1; F59B8.2.2; 4K204; CE03436; WBGene00010317; WP:CE03436 WormBase description: isocitrate dehydrogenase
H10E21.3 H10E21.3 P W All gene names: nhr-80; H10E21.3; H10E21.3a.1; H10E21.3a.2; 3A630; CE19488; CE28733; NM_064725; NM_181901; WBGene00003670; WP:CE19488; WP:CE28733 WormBase description: zinc finger protein
H22K11.1 H22K11.1 P W All gene names: asp-3; H22K11.1; ASP3_CAEEL; CE19495; NM_076741; WBGene00000216; WP:CE19495; XH411 WormBase description: asp-3 encodes an aspartyl protease homolog that is required, in parallel with ASP-4 but downstream of CLP-1 and TRA-3, for degenerative (necrotic-like) cell death in neurons induced by mutations such as mec-4(d), deg-3(d), or gsa-1(gf). WormBase CDS description: aspartyl protease
H39E23.1 H39E23.1 P W All gene names: par-1; zyg-14; H39E23.1; 5O592; CE23838; CE27768; WBGene00003916; WP:CE23838; WP:CE27768 WormBase description: par-1 encodes a serine-threonine kinase; maternally provided PAR-1 is essential for establishing early embryonic polarity; PAR-1 is membrane-associated and asymmetrically localized to the posterior cortex of late one-cell stage embryos; PAR-1 is continuously asymmetrically localized to the P lineage (germline blastomeres) at each subsequent division, and evenly distributed to the Z2 and Z3 germline precursors before eventually fading at embryonic morphogenesis.
K01C8.10 K01C8.10 P W All gene names: cct-4; K01C8.10; K01C8.10.1; K01C8.10.2; K01C8.10.3; K01C8.10.4; 2I575; CE02262; NM_063349; TCPD_CAEEL; WBGene00000379; WP:CE02262 WormBase description: cct-4 encodes a putative T complex chaperonin that affects fertility and body morphology and intergrity; expressed in touch receptor neurons. WormBase CDS description: T-complex protein
K02A4.1 K02A4.1 P W All gene names: bcat-1; eca-39; K02A4.1; BCAT_CAEEL; CE03457; ECA39; NM_077743; WBGene00001149; WP:CE03457; XN497 WormBase description: eca-39 encodes a branched-chain amino acid aminotransferase that, by homology, is predicted to catalyze the first reaction in the catabolism of essential branched-chain amino acids such as leucine, isoleucine, and valine; in C. elegans, large-scale RNA-mediated interference (RNAi) screens indicate that eca-39 activity is required for embryonic and larval development. WormBase CDS description: twt1 like protein
K02B9.4 K02B9.4 P W All gene names: elt-3; K02B9.4; CE23844; NM_077920; WBGene00001251; WP:CE23844; XO559 WormBase description: The elt-3 gene encodes a GATA transcription factor expressed in the embryonic hypodermis; specifically, it is expressed in expressed in all of the major hypodermal cells except the lateral seam cells. WormBase CDS description: GATA-binding transcription factor like
K02D7.4 K02D7.4 P W All gene names: dsc-4; K02D7.4; K02D7.4.1; K02D7.4.2; 4B68; CE33667; NM_067502; WBGene00001099; WP:CE33667 WormBase description: dsc-4 encodes the C. elegans ortholog of the large subunit of the microsomal triglyceride transfer protein; dsc-4 affects the length of the defecation cycle and genetically interacts with clk-1 with respect to defecation cycle length, and also with respect to the clk-1- dependent adjustment of defecation cycle length to temperature; a DSC-4::GFP fusion protein is expressed in the intestine beginning during embryonic elongation and continuing on through adulthood.
K02F2.2 K02F2.2 P W All gene names: K02F2.2; K02F2.2.1; K02F2.2.2; 1H413; CE17154; CEAHH; SAHH_CAEEL; WBGene00019322; WP:CE17154 WormBase description: S-adenosylhomocysteine hydrolase
K04D7.3 K04D7.3 P W All gene names: gta-1; K04D7.3; 4K947; CE06092; GABT_CAEEL; NM_069461; WBGene00001794; WP:CE06092 WormBase description: The gta-1 gene encodes an ortholog of the human gene GABAT, which when mutated leads to GABA-transaminase deficiency (OMIM:137150). WormBase CDS description: 4-aminobutyrate aminotransferase
K05B2.5 K05B2.5 P W All gene names: pes-22; K05B2.5; K05B2.5a.1; K05B2.5a.2; CE34052; CE39589; CE39590; NM_076437; WBGene00003986; WP:CE34052; WP:CE39589; WP:CE39590; XF540 WormBase description: pes-22 encodes a predicted transmembrane protein that is a member of the monocarboxylate porter subfamily of the major facilitator superfamily of transmembrane transporters; pes-22 was identified in promoter-trapping screens and by homology, is predicted to function in the transport of lactate and pyruvate across cell membranes, possibly as part of a metabolic pathway that allows these metabolites to be converted back to glucose when the organism is under high energy demand; however, as loss of pes-22 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of PES-22 in C. elegans development and/or behavior is not yet known; a pes-22 reporter is expressed in the excretory gland cells and the ventral nerve cord from late embryogenesis through adulthood, and also in the intestine in late embryos and early larvae.
K05G3.3 K05G3.3 P W All gene names: cah-3; K05G3.3; CAH3_CAEEL; CE04755; NM_078273; WBGene00000281; WP:CE04755; XR103 WormBase description: carbonic anhydrase 2. WormBase CDS description: carbonic anhydrase
K06A5.6 K06A5.6 P W All gene names: K06A5.6; K06A5.6.1; K06A5.6.2; 1H40; CE11776; WBGene00019433; WP:CE11776 WormBase description: acyl-coA dehydgrogenase
K07H8.6 K07H8.6 P W All gene names: vit-6; K07H8.6; 4J31; CE18026; CE28594; CE34921; VIT6_CAEEL; WBGene00006930; WP:CE18026; WP:CE28594; WP:CE34921 WormBase description: vitellogenin
K08C7.2 K08C7.2 P W All gene names: fmo-1; fmo-11; K08C7.2; K08C7.2.1; K08C7.2.2; K08C7.2.3; 4L427; CE31710; NM_069567; WBGene00001476; WP:CE31710 WormBase description: The fmo-11 gene encodes a flavin-containing monoxygenase; fmo-11 is homologous to the human genes FMO1, FMO2, and FMO3, which when mutated lead to trimethylaminuria (OMIM:602079). WormBase CDS description: flavin-containing monoxygenase
K08E4.1 K08E4.1 P W All gene names: spt-5; K08E4.1; 4M819; CE06145; NM_069882; SPT5H_CAEEL; WBGene00005015; WP:CE06145 WormBase description: translation initiation protein SPT5 like
K08E7.1 K08E7.1 P W All gene names: K08E7.1; CE11920; NM_070004; WBGene00010671; WP:CE11920
K08F4.7 K08F4.7 P W All gene names: gst-4; K08F4.7; 4K907; CE06155; CeGST1; GST4_CAEEL; NM_069447; WBGene00001752; WP:CE06155 WormBase description: gst-4 encodes a predicted glutathione S-transferase; mRNA is expressed in adults and accumulation increases in response to paraquat. WormBase CDS description: glutathione S-transferase
K08F8.1 K08F8.1 P W All gene names: K08F8.1; K08F8.1a.1; K08F8.1a.2; K08F8.1a.3; K08F8.1a.4; K08F8.1b.1; K08F8.1b.2; K08F8.1c.1; K08F8.1c.2; K08F8.1c.3; K08F8.1c.4; K08F8.1d.1; K08F8.1d.2; K08F8.1e.1; K08F8.1e.2; K08F8.1e.3; K08F8.1e.4; K08F8.1e.5; K08F8.1e.6; 2J37; CE03467; CE32906; CE35895; CE37257; CE37258; WBGene00010681; WP:CE03467; WP:CE32906; WP:CE35895; WP:CE37257; WP:CE37258 WormBase description: ribosomal S6 kinase
K10B3.8 K10B3.8 P W All gene names: gpd-2; K10B3.8; CE07371; G3P2_CAEEL; NM_076134; WBGene00001684; WP:CE07371; XD732 WormBase description: gpd-2 encodes one of four C. elegans glyceraldehyde-3-phosphate dehydrogenases (GAPDHs); by homology, GPD-2 is predicted to reversibly catalyze the oxidation and phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate during glycolysis; in C. elegans, GPD-2 and GPD-3 constitute the major GAPDH isoenzymes and are expressed at highest levels during postembryonic development, primarily in the actin-containing A and I zones of body-wall muscle; loss of gpd-2 function via RNA-mediated interference (RNAi) does not result in any abnormalities.
K10D3.1 K10D3.1 P W All gene names: glr-3; K10D3.1; 1H697; CE36553; NM_059616; WBGene00001614; WP:CE36553 WormBase description: glr-3 encodes a protein that contains a ligand-gated ion channel domain and a receptor family ligand binding domain with similarity to kainate-selective ionotropic glutamate receptor 2 (human GRIK2); expressed in the RIA neuron. WormBase CDS description: glutamate receptor
K11D2.2 K11D2.2 P W All gene names: asah-1; dod-7; K11D2.2; 1N99; ASAH1_CAEEL; CE12120; NM_060772; WBGene00010769; WP:CE12120 WormBase description: K11D2.2 is orthologous to the human gene N-ACYLSPHINGOSINE AMIDOHYDROLASE (ASAH; OMIM:228000), which when mutated leads to Farber lipogranulomatosis. WormBase CDS description: Human PHP32 protein like
K11G9.6 K11G9.6 P W All gene names: met-I; mtl-1; K11G9.6; 5H172; CE07379; MT1_CAEEL; NM_072295; WBGene00003473; WP:CE07379
K12H4.5 K12H4.5 P W All gene names: K12H4.5; K12H4.5.1; K12H4.5.2; 3J131; CE00270; WBGene00019680; WP:CE00270; YM65_CAEEL
M01A10.3 M01A10.3 P W All gene names: M01A10.3; 1G118; CE12232; WBGene00019693; WP:CE12232
M03F4.7 M03F4.7 P W All gene names: M03F4.7; CE12368; CE34060; WBGene00019760; WP:CE12368; WP:CE34060; XF588 WormBase description: calcium binding protein
M163.3 M163.3 P W All gene names: his-24; M163.3; CE12450; H11_CAEEL; HH1; NM_078009; WBGene00001898; WP:CE12450; XP109 WormBase description: The his-24 gene encodes a histone H1 isoform (H1.1) that is essential for chromatin silencing and germline development. WormBase CDS description: histone H1
M6.1 M6.1 P W All gene names: ifc-2; M6.1; CE31204; CE31205; CE34062; Cel IF C2; CelIF c2; IFC2_CAEEL; NM_171613; NM_171614; WBGene00002056; WP:CE31204; WP:CE31205; WP:CE34062; XB262 WormBase description: ifc-2 encodes three isoforms of an intermediate filament protein dispensable for viability but required for normal movement, growth rate, body size, body shape, and cuticle strength; IFC-2 is present in the cytoplasm of intestinal cells, and at the desmosomes of intestinal and pharyngeal cells.
M7.1 M7.1 P W All gene names: let-70; ubc-2; M7.1; 4L846; CE03482; NM_069664; UBC2_CAEEL; WBGene00002344; WP:CE03482 WormBase description: let-70 encodes a class I E2 ubiquitin conjugating enzyme; let-70 was identified in screens for essential genes and phenotypic analyses indicate that loss of let-70 activity results in embryonic and larval lethality with defects in sarcomere assembly; purified LET-70 can stimulate the self-ubiquitylation activities of CHN-1 and UFD-2, E4 ubiquitin conjugation factors and, in addition, can stimulate the CHN-1- and UFD-2-dependent multiubiquitylation of UNC-45, a myosin-directed chaperone; in this manner, LET-70 may regulate UNC-45 degradation and myosin assembly; RNA blot analyses and a let-70-lacZ reporter fusion reveal that let-70 is abundantly expressed at all stages of development, including the dauer larval stage; strong staining is observed in most somatic tissues until adult stages, when expression generally becomes restricted to the nervous system. WormBase CDS description: ubiquitin-conjugating enzyme E2-17 KD
R03D7.1 R03D7.1 P W All gene names: R03D7.1; 2L219; CE01609; METH_CAEEL; WBGene00010988; WP:CE01609 WormBase description: R03D7.1 is orthologous to the human gene METHIONINE SYNTHASE (MTR; OMIM:156570), which when mutated leads to disease. WormBase CDS description: 5-methyltetrahydrofolate-homocysteine methyltransferase
R04A9.4 R04A9.4 P W All gene names: ife-2; R04A9.4; CE04791; IF4E2_CAEEL; NM_075693; WBGene00002060; WP:CE04791; XB2 WormBase description: The ife-2 gene encodes a member of the Initiation Factor 4E (eIF4E) family. WormBase CDS description: eukaryotic initiation factor 4E (EIF-4E)
R07B1.10 R07B1.10 P W All gene names: lec-8; R07B1.10; R07B1.10.1; R07B1.10.2; CE26721; LEC8_CAEEL; NM_077248; WBGene00002271; WP:CE26721; XK469 WormBase description: galaptin domain
R07E5.7 R07E5.7 P W All gene names: R07E5.7; R07E5.7.1; R07E5.7.2; 3F510; CE00672; WBGene00011115; WP:CE00672
R08B4.1 R08B4.1 P W All gene names: grd-1; R08B4.1; CE34080; CE34081; WBGene00001690; WP:CE34080; WP:CE34081; XL733 WormBase description: grd-1 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, a Ground domain, an extended region of low-complexity sequence, and a Hint/Hog domain; GRD-1 is expressed in rectal cells; the Hint/Hog domain is predicted to cut GRD-1 into two halves and then covalently link cholesterol to the C-terminus of the Ground domain; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-1 is weakly required for normal molting; GRD-1 is also required for normal growth to full size, cuticle adhesion, and male tail development; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking. WormBase CDS description: groundhog
R08D7.5 R08D7.5 P W All gene names: R08D7.5; 3K65; CE33292; WBGene00011145; WP:CE33292; YNE5_CAEEL WormBase description: caltractin
R10E11.2 R10E11.2 P W All gene names: vha-2; R10E11.2; R10E11.2.1; R10E11.2.2; R10E11.2.3; 3K875; CE06290; NM_066765; WBGene00006911; WP:CE06290 WormBase description: vha-2 and vha-3 encode an ortholog of subunit c of the membrane-bound (V0) domain of vacuolar proton-translocating ATPase (V-ATPase); the protein encoded by vha-2 and vha-3 (VHA-2/3) is identical; VHA-2/3 is a predicted V-ATPase transmembrane rotor component, whose polypeptide sequence is identical to that of VHA-3; VHA-1 and VHA-2/3 comprise a closely related family of subunit c co-orthologs, predicted to carry protons from the cytosol to a-subunits (VHA-5, VHA-6, VHA-7, or UNC-32) for transmembrane export; VHA-2/3 is dispensable for viability, since vha-2/3(RNAi) animals have mostly healthy progeny; however, VHA-2 is required for ovulation and embryogenesis, since vha-2(RNAi) animals are sterile with polyploid, unmatured oocytes; VHA-2, along with VHA-15 and probably all V-ATPase subunits, is required for systemic RNAi, probably during endocytotic RNAi uptake; VHA-2 is required for necrosis, since vha-2(RNAi) suppresses necrotic neurodegeneration; vha-2 shares an operon with vha-1 and R10E11.6; both vha-2 and vha-1 are expressed in the excretory cell, the rectum, and a pair of cells posterior to the anus. WormBase CDS description: Vacuolar ATP synthase subunit
R10E11.8 R10E11.8 P W All gene names: vha-1; R10E11.8; R10E11.8.1; R10E11.8.2; R10E11.8.3; 3K871; CE06291; NM_066764; VATL1_CAEEL; WBGene00006910; WP:CE06291 WormBase description: vha-1 encodes an ortholog of subunit c of the membrane-bound (V0) domain of vacuolar proton-translocating ATPase (V-ATPase); VHA-1 is a predicted V-ATPase transmembrane rotor component; VHA-1 and VHA-2/3 comprise a closely related family of subunit c co-orthologs, predicted to carry protons from the cytosol to a-subunits (VHA-5, VHA-6, VHA-7, or UNC-32) for transmembrane export; VHA-1, like VHA-12 and VHA-17, antagonizes EFF-1-mediated cell fusion in hypodermal cells; VHA-1 is required for ovulation and embryogenesis, since vha-1(RNAi) animals are sterile with polyploid, unmatured oocytes and dead progeny; VHA-1 is required for alae formation, like the V0 subunits VHA-4 and VHA-5, but not like the V1 subunits VHA-8 or VHA-13; vha-1 shares an operon with vha-2 and R10E11.6; both vha-1 and vha-2 are expressed in the excretory cell, the rectum, and a pair of cells near the anus. WormBase CDS description: ATP synthase subunit C (2 domains)
R11A5.2 R11A5.2 P W All gene names: R11A5.2; 1I434; CE12724; WBGene00011230; WP:CE12724
R11A5.4 R11A5.4 P W All gene names: R11A5.4; R11A5.4c.1; R11A5.4c.2; R11A5.4c.3; R11A5.4d.1; R11A5.4d.2; R11A5.4d.3; R11A5.4d.4; R11A5.4d.5; 1I447; CE12728; CE36358; CE36359; CE36360; WBGene00011232; WP:CE12728; WP:CE36358; WP:CE36359; WP:CE36360 WormBase description: phosphoenolpyruvate carboxykinase
R11D1.11 R11D1.11 P W All gene names: dhs-21; R11D1.11; 5N212; CE39954; DCXR_CAEEL; NM_073781; WBGene00000984; WP:CE39954 WormBase description: dhs-21 encodes a member of the short-chain dehydrogenases/reductases family (SDR) expressed in the intestine, hypodermis, uterus, and spermatheca. WormBase CDS description: Mouse adipocyte P27 protein like
R11H6.1 R11H6.1 P W All gene names: pes-9; R11H6.1; R11H6.1.1; R11H6.1.2; R11H6.1.3; 5P76; CE12770; NM_074209; WBGene00003982; WP:CE12770 WormBase description: pes-9 encodes a zinc metallopeptidase; pes-9 was originally identified in a promoter trap screen for sequences that direct reporter gene expression in specific cell types during C. elegans development; pes-9 sequences direct expression in a limited number of cells in the early embryo and in putative head and tail hypodermal cells in adults; after some confusion, the pes-9 reporter gene fusion was mapped to R11H6.1. WormBase CDS description: Yeast hypothetical 52.9 KD protein like
R12C12.6 R12C12.6 P W All gene names: R12C12.6; 2G336; CE02851; CE39619; WBGene00020026; WP:CE02851; WP:CE39619
R13A5.8 R13A5.8 P W All gene names: rpl-9; R13A5.8; R13A5.8.1; R13A5.8.2; 3I662; CE01380; NM_066259; RL9_CAEEL; WBGene00004420; WP:CE01380 WormBase description: rpl-9 encodes a large ribosomal subunit L9 protein that affects fertility and embryonic viability. WormBase CDS description: Ribosomal protein L9
R13H4.5 R13H4.5 P W All gene names: R13H4.5; R13H4.5.1; R13H4.5.2; 5M341; CE12808; WBGene00011263; WP:CE12808 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
T02G5.8 T02G5.8 P W All gene names: kat-1; T02G5.8; 2H367; CE29990; NM_063054; WBGene00002183; WP:CE29990 WormBase description: kat-1 encodes a homolog of the human gene ACAT1, which when mutated leads to alpha-methylacetoaceticaciduria (OMIM:203750). WormBase CDS description: acetoacetyl-C0A thiolase
T03E6.7 T03E6.7 P W All gene names: cpl-1; T03E6.7; T03E6.7.1; T03E6.7.2; 5R74; CE16333; NM_074798; O45734_CAEEL; WBGene00000776; WP:CE16333 WormBase description: cpl-1 encodes a member of the cathepsin L-like cysteine protease family required for embryonic viability and normal growth; expressed in eggshells and throughout early embryos, accumulates in intestinal cells during late embryogenesis, and expressed in the cuticle, gonad, and pharynx later in development. WormBase CDS description: cathepsin-like protease
T04B2.5 T04B2.5 P W All gene names: T04B2.5; T04B2.5.1; T04B2.5.2; 4K822; CE06351; WBGene00011423; WP:CE06351
T05A6.1 T05A6.1 P W All gene names: cki-1; T05A6.1; 2I101; CE03628; CKI1_CAEEL; NM_063240; WBGene00000516; WP:CE03628 WormBase description: cki-1 encodes a homolog of the mammalian cyclin-dependent kinase inhibitor p27/KIP1 that is required for the arrest of cell division in larval blast lineages, dauer larvae and starved L1 larvae; excess CKI-1 expression prematurely stops cell division while cki-1(RNAi) induces extra cell divisions, indicating that CKI-1 quantitatively regulates the amount of mitosis in postembryonic worms.
T05A7.4 T05A7.4 P W All gene names: hmg-11; hmg-I-alpha; T05A7.4; T05A7.4.1; T05A7.4.2; 2E963; CE04890; NM_062424; WBGene00001976; WP:CE04890 WormBase description: nuclear phosphoprotein (weak)
T05B11.3 T05B11.3 P W All gene names: clic-1; T05B11.3; 5i214; CE13219; WBGene00020246; WP:CE13219
T05C12.7 T05C12.7 P W All gene names: cct-1; tcp-1; T05C12.7; T05C12.7.1; T05C12.7.2; 2I477; CE02319; NM_063321; TCPA_CAEEL; WBGene00000377; WP:CE02319 WormBase description: eukaryotic cytosolic chaperonin; affects viability and fertility, and is expressed in various muscle and neuronal cells: near the pharynx, near the anal sphincter, in the ventral nerve cord and the nerve ring; occasionally the expression is visible in hypodermal cells and in some vulval cells. WormBase CDS description: T-complex protein
T05G5.10 T05G5.10 P W All gene names: iff-1; T05G5.10; 3K836; CE37787; IF5A1_CAEEL; NM_066751; WBGene00002064; WP:CE37787 WormBase description: iff-1 encodes an eIF-5A homolog that affects fertility and is required for germ cell proliferation and for some P granule components to localize properly; expression is germline specific and mRNA is expressed in the distal region of gonads where germ cells actively proliferate. WormBase CDS description: Initiation factor 5A
T06E6.2 T06E6.2 P W All gene names: cyb-2; cyb-3; T06E6.2; T06E6.2a.1; T06E6.2a.2; 5P877; CCNB3_CAEEL; CE13315; CE27776; NM_074424; WBGene00000868; WP:CE13315; WP:CE27776 WormBase description: cyb-3 encodes a member of the cyclin B family that is required for embryonic viability, and may be involved with sister chromatid segregation.
T08B2.10 T08B2.10 P W All gene names: rps-17; T08B2.10; T08B2.10.1; T08B2.10.2; 1G796; CE26948; NM_059394; RS17_CAEEL; WBGene00004486; WP:CE26948 WormBase description: rps-17 encodes a small ribosomal subunit S17 protein. WormBase CDS description: 40S ribosomal protein S17
T08G5.10 T08G5.10 P W All gene names: met-II; mtl-2; T08G5.10; 5O498; CE25109; MT2_CAEEL; NM_074081; WBGene00003474; WP:CE25109 WormBase description: mtl-2 encodes a metallothionein, a small, cysteine-rich, metal-binding protein; MTL-2 functions in metal detoxification and homeostasis and stress adaptation; MTL-2 expression is induced in larval and adult intestinal cells following exposure to cadmium or heat stress; MTL-2 intestinal expression is dependent upon ELT-2, an intestine-specific GATA-type transcription factor.
T10B11.2 T10B11.2 P W All gene names: T10B11.2; 1H511; CE18241; WBGene00020398; WP:CE18241
T10B5.5 T10B5.5 P W All gene names: T10B5.5; T10B5.5b.1; T10B5.5b.2; 5C353; CE28255; CE33316; WBGene00020391; WP:CE28255; WP:CE33316
T12A7.1 T12A7.1 P W All gene names: gem-4; tag-121; T12A7.1; T12A7.1.1; T12A7.1.2; 4M511; CE27445; NM_069824; WBGene00001577; WP:CE27445 WormBase description: gem-4 encodes a Ca[2+]-dependent phosphatidylserine binding protein (copine) that antagonizes GON-2 in gonadal cell division, with no other obvious function in normal animals; GEM-4 is highly similar to three human proteins, copine I, copine III, and KIA1599 (40% identity over 590 residues); GEM-4 is also similar to its C. elegans paralog, F26D10.4 (73% identity over 637 residues), with at least three other copines being encoded by the C. elegans genome; since both GEM-4 and GON-2 are predicted to be plasma membrane proteins, they may interact directly. WormBase CDS description: C2 domain (2 domains)
T14G10.1 T14G10.1 P W All gene names: pps-1; T14G10.1; T14G10.1.1; T14G10.1.2; 4K927; CE06447; NM_069456; WBGene00004091; WP:CE06447 WormBase description: pps-1 is orthologous to human PAPSS1 (OMIM:603262) and human PAPSS2 (OMIM:603005, mutated in spondyloepimetaphyseal dysplasia). WormBase CDS description: sulphate adenyltransferase
T19B10.11 T19B10.11 P W All gene names: mxl-1; T19B10.11; 5L725; CE16417; NM_073455; WBGene00003509; WP:CE16417 WormBase description: Helix-loop-helix DNA-binding domain
T20B3.2 T20B3.2 P W All gene names: tni-3; T20B3.2; 5R314; CE20087; NM_074849; TNNI3_CAEEL; WBGene00006585; WP:CE20087 WormBase description: Troponin
T21B10.7 T21B10.7 P W All gene names: T21B10.7; T21B10.7.1; T21B10.7.2; 2J219; CE16437; TCPB_CAEEL; WBGene00011889; WP:CE16437 WormBase description: t-complex protein 1
T21H3.1 T21H3.1 P W All gene names: T21H3.1; 5B657; CE13898; CE38551; WBGene00020662; WP:CE13898; WP:CE38551
T22C1.6 T22C1.6 P W All gene names: T22C1.6; 1I521; CE24002; WBGene00011917; WP:CE24002 WormBase description: myosin
T22H6.2 T22H6.2 P W All gene names: T22H6.2; T22H6.2a.1; T22H6.2a.2; CE03697; CE26824; P5CS_CAEEL; WBGene00011938; WP:CE03697; WP:CE26824; XN405 WormBase description: 1-pyroline-5-carboxylate synthetase
T27E4.8 T27E4.8 P W All gene names: hsp-16.1; hsp-16; T27E4.8; 5J568; CE14249; NM_072953; WBGene00002015; WP:CE14249 WormBase description: hsp-16.1 encodes a 16-kD heat shock protein (HSP) that is a member of the hsp16/hsp20/alphaB-crystallin (HSP16) family of heat shock proteins, and that is identical to the protein encoded by hsp-16.11; an hsp-16.1 reporter fusion, expressed broadly but most strongly in muscle and hypodermis, is induced solely in response to heat shock or other environmental stresses; expression is detectable in somatic tissues in post-gastrulation embryos, all larval stages, and in adults; HSP-16.1 is likely to function as a passive ligand temporarily preventing unfolded proteins from aggregating. WormBase CDS description: heat shock protein HSP16-1
T27F7.3 T27F7.3 P W All gene names: PIG-B; T27F7.3; T27F7.3b.1; T27F7.3b.2; 2F282; CE27214; CE30458; WBGene00020868; WP:CE27214; WP:CE30458
T28C12.4 T28C12.4 P W All gene names: T28C12.4; 5G805; CE14343; CE14345; O16695_CAEEL; WBGene00020891; WP:CE14343; WP:CE14345 WormBase description: esterase
T28D9.2 T28D9.2 P W All gene names: CeSC35-2; rsp-5; srp-3; T28D9.2; 2G781; CE28094; CE36572; CE36573; CE36574; NM_062906; NM_062907; NM_062908; NM_062909; RSP5_CAEEL; WBGene00004702; WP:CE28094; WP:CE36572; WP:CE36573; WP:CE36574 WormBase description: splicing factor
W01A8.2 W01A8.2 P W All gene names: W01A8.2; 1H630; WBGene00012164
W08D2.4 W08D2.4 P W All gene names: fat-3; W08D2.4; 4K569; CE25153; NM_069351; Q23221_CAEEL; WBGene00001395; WP:CE25153 WormBase description: The fat-3 gene encodes a delta-6 fatty acid desaturase ('linoleoyl-CoA desaturase') containing an N-terminal cytochrome b5 domain; FAT-3 expressed in yeast uses linoleic and alpha-linolenic acid as substrates; FAT-3 is absolutely required in vivo for synthesis of delta-6 fatty acids, and also required for fully normal synthesis of C20 fatty acids; FAT-3 is required for a normally fast growth rate and movement speed, and for normal defecation rhythms and fertility.
W08E3.3 W08E3.3 P W All gene names: tag-210; W08E3.3; 1N935; CE14708; TG210_CAEEL; WBGene00012344; WBGene00044075; WP:CE14708 WormBase description: GTP-binding protein like
W09C5.6 W09C5.6 P W All gene names: rpl-31; W09C5.6; W09C5.6a.1; W09C5.6a.2; W09C5.6b.1; W09C5.6b.2; W09C5.6b.3; W09C5.6b.4; W09C5.6b.5; W09C5.6b.6; 1O244; CE20168; CE20169; NM_060990; NM_060991; RL31_CAEEL; WBGene00004445; WP:CE20168; WP:CE20169 WormBase description: rpl-31 encodes a large ribosomal subunit L31 protein. WormBase CDS description: Ribosomal protein L31e
Y22F5A.4 Y22F5A.4 P W All gene names: lys-1; Y22F5A.4; Y22F5A.4.1; Y22F5A.4.2; 5K759; CE16605; NM_073241; O62415_CAEEL; WBGene00003090; WP:CE16605
Y25C1A.13 Y25C1A.13 P W All gene names: Y25C1A.13; Y25C1A.A; 2D400; CE21481; WBGene00021296; WP:CE21481 WormBase description: enoyl-CoA hydratase/isomerase
Y37D8A.17 Y37D8A.17 P W All gene names: Y37D8A.17; 3O12; CE20221; TMM33_CAEEL; WBGene00012555; WP:CE20221
Y43F8C.2 Y43F8C.2 P W All gene names: nlp-26; Y43F8C.2; Y43F8C.2.1; Y43F8C.2.2; 5U89; CE21900; NM_075401; WBGene00003764; WP:CE21900 WormBase description: nlp-26 encodes a predicted neuropeptide not found in multigene families within C. elegans and is not clearly related to other well-characterized neuropeptides.
Y47D3B.2 Y47D3B.2 P W All gene names: nlp-21; Y47D3B.2; 3M478; CE19175; CE24343; NM_067065; NM_067066; WBGene00003759; WP:CE19175; WP:CE24343 WormBase description: nlp-21 encodes nine predicted neuropeptide-like proteins; in C. elegans, nlp-21 is part of the GGARAF neuropeptide family that also contains nlp-9; nlp-21 is expressed in a variety of neurons, including AFD, five head neurons, the ventral nerve cord, one anterior pharyngeal neuron, and one tail neuron; nlp-21 expression is also detected in the embryo and the intestine; as loss of nlp-21 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of nlp-21-encoded peptides in development and/or behavior is not yet known.
Y56A3A.18 Y56A3A.18 P W All gene names: Y56A3A.18; Y56A3A.18.1; Y56A3A.18.2; 3N8; CE22586; WBGene00013236; WP:CE22586
Y56A3A.19 Y56A3A.19 P W All gene names: Y56A3A.19; Y56A3A.O; 3N4; CE22587; WBGene00013237; WP:CE22587 WormBase description: acyl-carrier protein
Y66H1B.4 Y66H1B.4 P W All gene names: spl-1; Y66H1B.4; 4B134; CE20348; NM_067512; SGPL_CAEEL; WBGene00004981; WP:CE20348; spl
Y73F4A.2 Y73F4A.2 P W All gene names: Y73F4A.2; 4J806; CE20368; DMON1_CAEEL; WBGene00013515; WP:CE20368
Y75B12B.5 Y75B12B.5 P W All gene names: cyn-3; cyp-3; Y75B12B.5; Y75B12B.5.1; Y75B12B.5.2; 5P671; CE20374; CYP3_CAEEL; NM_074350; WBGene00000879; WP:CE20374 WormBase description: cyp-3 encodes an abundantly expressed cyclophilin A isoform with peptidyl-prolyl isomerase activity in vitro, which closely resembles the prototypical CypA and is thus likely to be a member of the cytosolic CsA-binding cyclophilin subfamily; cyp-3 is exclusively expressed in the single anterior excretory cell, and is dispensable for viability and gross morphology in mass RNAi screens. WormBase CDS description: Peptidyl-prolyl cis-trans isomerases
Y75B8A.4 Y75B8A.4 P W All gene names: Y75B8A.4; Y75B8A.4.1; Y75B8A.4.2; 3N201; CE23016; WBGene00013541; WP:CE23016 WormBase description: ATPases associated with various cellular activities (AAA)
Y76A2B.5 Y76A2B.5 P W All gene names: Y76A2B.5; 3O636; CE19277; Q9XWC9_CAEEL; WBGene00013577; WP:CE19277
ZC373.1 ZC373.1 P W All gene names: ZC373.1; ZC373.1.1; ZC373.1.2; CE31670; WBGene00013866; WP:CE31670; XK675 WormBase description: The ZC373.1 gene encodes an ortholog of the human gene CYSTATHIONINE-BETA-SYNTHASE (CBS), which when mutated leads to homocystinuria (OMIM:236200). WormBase CDS description: cystathionine beta-synthase
ZC395.10 ZC395.10 P W All gene names: ZC395.10; ZC395.10.1; ZC395.10.2; 3G364; CE01436; WBGene00022599; WP:CE01436; YOCA_CAEEL
ZC395.2 ZC395.2 P W All gene names: clk-1; coq-1; coq-7; ZC395.2; 3G369; CE01438; COQ7_CAEEL; NM_065727; WBGene00000536; WP:CE01438 WormBase description: The clk-1 gene partially controls lifespan in vivo; it encodes a homolog of the yeast COQ9 protein, and is necessary for the biosynthesis of ubiquinone (UQ(9)) from demethoxyubiquinone (DMQ(9)).
ZC416.6 ZC416.6 P W All gene names: ZC416.6; 4E374; CE28160; WBGene00022610; WP:CE28160 WormBase description: protease
ZK1098.10 ZK1098.10 P W All gene names: egl-39; unc-16; ZK1098.10; 3K645; CE00363; CE31846; JIP_CAEEL; NM_171221; WBGene00006755; WP:CE00363; WP:CE31846 WormBase description: unc-16 encodes a homolog of murine JIP3/JSAP and Drosophila SUNDAY DRIVER that is involved in vesicle transport, and that affects egg laying, locomotion, and defecation and physically interacts with JNK and JNK kinases; UNC-16 is expressed in neurons of the ventral cord, retrovesicular and preanal ganglia, the nerve ring, intestinal cells, seam and hypodermal cells, body wall and head muscle, and pharynx.
ZK112.1 ZK112.1 P W All gene names: pcp-1; ZK112.1; 3I849; CE25679; NM_066287; PCP1_CAEEL; WBGene00003956; WP:CE25679
ZK1251.2 ZK1251.2 P W All gene names: ins-7; ZK1251.2; 4K446; CE03849; ILB4_CAEEL; NM_069316; WBGene00002090; WP:CE03849 WormBase description: ins-7 encodes an insulin/IGF-1-like peptide; INS-7 is one of 38 insulin-like peptides in C. elegans; INS-7 likely functions as an agonist for the DAF-2 insulin/IGF-1 receptor, as loss of ins-7 activity via RNAi results in: 1) a significantly increased lifespan that is not further extended in long-lived daf-2 mutant animals, and 2) an increased frequency of dauer formation in animals containing an incompletely penetrant daf-2 mutation; an ins-7 promoter fusion is expressed in amphid sensory neurons, labial neurons, the nerve ring, and ventral cord and tail neurons; ins-7 expression is positively regulated by DAF-2-mediated insulin signaling, suggesting that a positive feedback loop involving INS-7 may amplify DAF-2 pathway activity.
ZK287.5 ZK287.5 P W All gene names: Ce-rbx-1; rbx-1; ZK287.5; ZK287.5.1; ZK287.5.2; 5K170; CE06614; NM_073095; RBX1_CAEEL; WBGene00004320; WP:CE06614 WormBase description: The rbx-1 gene encodes an ortholog of the mammalian RING box protein RBX1 (or ROC1), which interacts with several cullins and is a subunit of both the von Hippel-Lindau (VHL) tumor suppressor complex and of the SCF ubiquitin-ligase (E3) complex. WormBase CDS description: Zinc finger, C3HC4 type (RING finger)
ZK430.2 ZK430.2 P W All gene names: tag-231; ZK430.2; 2E711; CE05079; WBGene00022740; WBGene00044063; WP:CE05079 WormBase description: ammonium transport protein
ZK455.1 ZK455.1 P W All gene names: aco-1; gei-22; ZK455.1; ZK455.1.1; ZK455.1.2; ACOC_CAEEL; CE03812; NM_077497; WBGene00000040; WP:CE03812; XL961 WormBase description: aco-1 encodes an aconitase that is homologous to mammalian iron regulatory protein-1 (IRP1); aco-1 activity is required for normal brood sizes and, under iron stress conditions, for normal lifespan and L4-to-adult growth rates; ACO-1 physically interacts with GEX-3; like IRP1, ACO-1 has aconitase activity and is post-translationally regulated by iron, but, unlike IRP1, it lacks RNA-binding activity; ACO-1 is predicted to be mitochondrial, and its mRNA levels appear to decrease in response to iron treatment. WormBase CDS description: iron-responsive element-binding like protein
ZK470.5 ZK470.5 P W All gene names: nck-1; tag-22; ZK470.5; ZK470.5b.1; ZK470.5b.2; CE29645; CE31270; WBGene00006410; WP:CE29645; WP:CE31270; XE768 WormBase description: tag-22 encodes a protein with similarity to the human NCK adaptor protein 2 and orthologous to C.
ZK6.7 ZK6.7 P W All gene names: ZK6.7; 5A865; CE18444; CE29647; WBGene00022642; WP:CE18444; WP:CE29647 WormBase description: lipase
ZK637.3 ZK637.3 P W All gene names: tag-256; ZK637.3; 3J981; CE00434; TG256_CAEEL; WBGene00014023; WP:CE00434
ZK637.5 ZK637.5 P W All gene names: tag-205; ZK637.5; 3J985; ARSA_CAEEL; CE00436; WBGene00014025; WP:CE00436 WormBase description: ArsA
ZK652.2 ZK652.2 P W All gene names: tomm-7; ZK652.2; 3I951; CE00448; NM_066305; TOM7_CAEEL; WBGene00022783; WP:CE00448
ZK816.4 ZK816.4 P W All gene names: ZK816.4; CE39081; WBGene00022827; WP:CE39081; XD968