Kunitomo et al 2005, S2 sensory neuron-expressed g, 17 genes

Gene list file name:Kunitomo2005_S2_20_sensory_neurons
Type of gene identifier:Cosmid name
Description:Kunitomo et al 2005 Supplementary 2: 20 sensory neuron-expressed genes  
Organism:Caenorhabditis elegans (nematode)
Gene list type:Experimental

Gene name             Source Gene ID          Annotation                                                  Date       Added by    

B0240.3 B0240.3 P W All gene names: daf-11; B0240.3; 5M200; CE05174; NM_073559; WBGene00000907; WP:CE05174 WormBase description: The daf-11 gene encodes a guanylate cyclase that affects dauer formation, chemotaxis, and axon formation; it is genetically upstream of daf-12 with respect to dauer larvae formation and is expressed in a subset of amphid neurons. WormBase CDS description: guanylate cyclase
C02F4.2 C02F4.2 P W All gene names: cna-1; pph-3; pph2B-A; tax-6; C02F4.2; 4L258; CE07853; CE33593; PP2B; Q86MD4_CAEEL; WBGene00006527; WP:CE07853; WP:CE33593 WormBase description: tax-6 encodes an ortholog of calcineurin A that is required for inhibition and adaptation of several sensory neurons and for the normal regulation of egg-laying by serotonin; TAX-6 stimulates transcription of rcn-1, and binds RCN-1 protein if free Ca[2+] is present; in general, calcineurin positively regulates calcium-dependent signaling.
C05D2.1 C05D2.1 P W All gene names: daf-4; C05D2.1; 3G721; CE16827; CE32114; CE33555; DAF4_CAEEL; NM_065810; WBGene00000900; WP:CE16827; WP:CE32114; WP:CE33555 WormBase description: daf-4 encodes a transmembrane serine/threonine kinase that is the sole C. elegans ortholog of the type II transforming growth factor-beta (TGF-b) receptors; DAF-4 activity is required for several biological processes, including entry into and exit from the dauer larval stage, body size determination, male tail patterning, egg laying, chemosensory neuron specification, and increased thermotolerance; in regulating dauer larval development, DAF-4 acts in parallel with the insulin signaling pathway and likely partners with the DAF-1 type I TGF-b receptor to receive a signal from the DAF-7 TGF-b ligand; in body size determination and male tail patterning, DAF-4 likely partners with the SMA-6 type I receptor and responds to signals from the DBL-1 ligand; DAF-4 expression begins in late embryogenesis and continues through larval and adult stages; consistent with its role in many developmental processes, DAF-4 localizes to the plasma membrane of several tissues including head and tail neurons, the pharynx, intestine, ventral nerve cord, tail hypodermis, and body wall muscle.
D2030.10 D2030.10 P W All gene names: aex-1; D2030.10; 1I183; CE30740; CE30741; NM_170901; WBGene00000084; WP:CE30740; WP:CE30741 WormBase description: AEX-1 is a novel C2 domain protein; C2 is a proposed calcium binding domain; AEX-1 is weakly similar to the rat protein Munc13, which regulates vesicle exocytosis; AEX-1 regulates UNC-13 localization; mutation of dgk-1, or a gain-of-function mutation of egl-30, suppresses the aex-1 mutant phenotype.
F08F8.3 F08F8.3 P W All gene names: F08F8.3; CE27931; CE30650; WBGene00002182; WP:CE27931; WP:CE30650
F10C1.2 F10C1.2 P W All gene names: CEL-IF-B1; ifb-1; vab-21; F10C1.2; F10C1.2a.1; F10C1.2a.2; 2G61; CE02618; CE02619; Cel IF b1; CelIF b1; IFB1_CAEEL; NM_062735; NM_062736; WBGene00002053; WP:CE02618; WP:CE02619 WormBase description: ifb-1 (also known as vab-21) encodes two isoforms of an essential intermediate filament protein that is coexpressed with the essential IF proteins IFA-1, IFA-2, and IFA-3, along with IFA-4; IFB-1 is required for embryonic development and epidermal morphogenesis; IFB-1 forms heteropolymeric intermediate filaments in vitro with an equimolar mixture of IFA-1, IFA-2, or IFA-3, and binds IFA-4 in blot overlay assays; IFB-1 resides in attachment structures of epidermal cells, found in sites undergoing mechanical stress; the two isoforms are expressed in different tissues and have distinct functions, since ifb-1A(RNAi) larvae have detached muscle cells, while ifb-1B(RNAi) larvae have detached cuticle. WormBase CDS description: Intermediate filament protein
F18C12.1 F18C12.1 P W All gene names: avr-1; caf-2; che-3; che-8; osm-2; F18C12.1; 1I638; CE32386; NM_059820; WBGene00000485; WP:CE32386 WormBase description: The dynein heavy chain (DHC) 1b isoform that affects the establishment and maintainance of the structural integrity of sensory cilia and also has a role in intraflagellar transport; it is expressed in ciliated sensory neurons. WormBase CDS description: dynein heavy chain
F29C4.1 F29C4.1 P W All gene names: daf-1; F29C4.1; 4A889; CE17719; CE31492; DAF1_CAEEL; WBGene00000897; WP:CE17719; WP:CE31492 WormBase description: daf-1 encodes a TGF-beta type I receptor homolog required, in association with the TGF beta-like type II receptor DAF-4, for the regulation of dauer formation by environmental signals through the ASI chemosensory neuron; DAF-1 is bound by BRA-1 and has an intracellular serine-threonine kinase domain; mutations in daf-1 result in constitutive formation of dauer larvae even in abundant food. WormBase CDS description: protein kinase
F38B2.1 F38B2.1 P W All gene names: ifa-1; F38B2.1; CE31506; CE31507; Cel IF A1; CelIF a1; IFA1_CAEEL; NM_171777; NM_171778; WBGene00002050; WP:CE31506; WP:CE31507; XL893 WormBase description: IFA-1 encodes an essential intermediate filament protein that is coexpressed with the essential IF protein IFB-1; IFA-1 is required for survival past the L1 larva stage, and a normal intestine; IFA-1 forms heteropolymeric intermediate filaments in vitro with an equimolar mixture of IFB-1; IFA-1 is predicted to function as a structural component of the cytoskeleton, and is required for larval development and normal intestinal morphology; ifa-1 is expressed in amphid sensory neurons, in tail neurons and other unidentified neurons, some pharyngeal muscles, the pharyngeal-intestinal valve, the vulva, and the rectum.
F38G1.1 F38G1.1 P W All gene names: che-2; F38G1.1; F38G1.1.1; F38G1.1.2; CE25876; NM_075705; WBGene00000484; WP:CE25876; XB103 WormBase description: che-2 encodes a protein that contains G-protein beta-like WD-40 repeats that affects chemotaxis, dauer formation, and longevity; expressed in the cilia of most ciliated sensory neurons, some head neurons, and male tail rays. WormBase CDS description: G-beta-repeats
F46A9.6 F46A9.6 P W All gene names: mec-8; F46A9.6; F46A9.6.1; F46A9.6.2; F46A9.6.3; 1K18; CE08260; NM_060107; Q19018_CAEEL; WBGene00003172; WP:CE08260 WormBase description: mecanosensory gene mec-8
F53A2.4 F53A2.4 P W All gene names: nud-1; F53A2.4; 3O429; CE16096; NM_067348; WBGene00003829; WP:CE16096 WormBase description: nud-1 encodes the C. elegans ortholog of the Aspergillus nidulans nudC, which mediates nuclear migration along Aspergillus hyphae.
F53H4.1 F53H4.1 P W All gene names: csb-1; F53H4.1; CE33793; Cecsb; NM_078206; WBGene00000803; WP:CE33793; XQ480 WormBase description: csb-1 is orthologous to human gene ERCC6 (OMIM:133530, mutated in Cockayne syndrome); CSB-1 is required for embryonic viability, and represses UV-induced apoptosis in germ cells. WormBase CDS description: excision repair protein ERCC-6 like
F55C10.1 F55C10.1 P W All gene names: cnb-1; F55C10.1; 5L857; CE32679; NM_073484; WBGene00000554; WP:CE32679 WormBase description: cnb-1 encodes an ortholog of calcineurin B, the regulatory subunit of the protein phosphatase 2B with four EF-hand motifs for calcium binding, that binds TAX-6 (a calcineurin A ortholog) in a calcium-dependent manner; CNB-1 binds calcium, enhances the phosphatase activity of TAX-6 in vitro, promotes transcription of rcn-1, and is required for normal cuticle formation, sperm morphology, and brood size. WormBase CDS description: calcineurin B
K08C7.4 K08C7.4 P W All gene names: K08C7.4; 4L444; CE35587; WBGene00010647; WP:CE35587
Y102E9.1 Y102E9.1 P W All gene names: odr-4; Y102E9.1; Y102E9.1a.1; Y102E9.1a.2; Y102E9.1a.3; Y102E9.1a.4; 3H823; CE28101; CE32953; CE32954; NM_066076; WBGene00003851; WP:CE28101; WP:CE32953; WP:CE32954 WormBase description: odr-4 encodes a novel type II membrane protein required for the localization of a subset of seven transmembrane domain odorant receptors, including ODR-10, to the cilia of olfactory neurons, it affects response to a subset of AWA- and AWC- mediated olfactory responses, and is required for social feeding of npr-1 mutant animals; expressed in 12 pairs of chemosensory neurons.
Y41G9A.1 Y41G9A.1 P W All gene names: osm-5; Y41G9A.1; CE28361; NM_076110; WBGene00003885; WP:CE28361; XD609 WormBase description: The osm-5 gene encodes a homolog of the murine cystic kidney disease gene Tg737 that is required for the production of cilia in sensory neurons.