|Gene list file name:||Fox2005_S14-T2_unc-4_neuron-transcript_Calcium-Cha|
|Type of gene identifier:||Cosmid name|
|Description:||Fox et al 2005 Additional File 14/Table2: Summary of unc-4::GFP enriched and expressed (EGs) transcripts in selected categories. This file is an expanded version of Table 2 (see text) in which EGs are added to the list of enriched genes. Genes are organized as in Table 2 according to molecular function (KOG description, other description http://www.wormbase.org). Statistical rank is indicated for each enriched transcript and "EG" designates transcripts that are EGs.|
|Organism:||Caenorhabditis elegans (nematode)|
|Gene list type:||Experimental|
Gene name Source Gene ID Annotation Date Added by
C07A9.4 C07A9.4 P W All gene names: ncx-6; C07A9.4; 3K800; CE33595; NCX6_CAEEL; NM_066745; WBGene00003571; WP:CE33595 WormBase description: Na/Ca,K antiporter
C11D2.6 C11D2.6 P W All gene names: nca-1; C11D2.6; 4G922; CE31301; CE37194; CE37195; CE37196; NM_068525; NM_068526; NM_171352; NM_171353; WBGene00003557; WP:CE31301; WP:CE37194; WP:CE37195; WP:CE37196
C48A7.1 C48A7.1 P W All gene names: eat-12; egl-19; pat-5; C48A7.1; 4I183; CE28820; CE31165; NM_171379; WBGene00001187; WP:CE28820; WP:CE31165 WormBase description: egl-19 encodes an ortholog of the alpha subunit of mammalian L-type calcium ion channels that affects muscle contraction in late embryonic morphogenesis, movement, egg-laying, mating and feeding; egl-19 is expressed in muscle cells and some neurons.
C50C3.9 C50C3.9 P W All gene names: unc-36; unc-72; C50C3.9; 3J284; CE32168; CE39702; NM_066388; UNC36_CAEEL; WBGene00006772; WP:CE32168; WP:CE39702; eT1
F35C12.2 F35C12.2 P W All gene names: ncx-4; F35C12.2; 1K387; CE28020; NM_060203; WBGene00003569; WP:CE28020 WormBase description: Na/Ca,K exchanger
K11C4.5 K11C4.5 P W All gene names: kra-1; ryr-1; unc-68; K11C4.5; 5H382; CE12116; NM_072352; WBGene00006801; WP:CE12116 WormBase description: unc-68 encodes a ryanodine receptor ortholog that is expressed in body-wall muscle cells and is required for normal body tension and locomotion; unc-68 mutants are flaccid, sluggish, and resistant to ryanodine, but have normal muscle ultrastructure; UNC-68 is dispensable for excitation-contraction coupling itself, but may amplify its calcium signals; the unc-68/kra-1(kh30) mutation is an S1444N substitution at a putative protein kinase C phosphorylation site; UNC-68 reduced unc-103(sy557)-induced spicule protraction by one half; unc-68 is orthologous to the human genes RYR1 (OMIM:180901, mutated in malignant hyperthermia and central core disease), RYR2 (OMIM:180902, mutated in stress-induced polymorphic ventricular tachycardia), and RYR3 (OMIM:180903). WormBase CDS description: ryanodine receptor
T02C5.5 T02C5.5 P W All gene names: unc-2; T02C5.5; T02C5.5d.1; T02C5.5d.2; T02C5.5d.3; CE29459; CE31225; CE34591; CE34980; NM_171638; NM_171639; NM_171942; WBGene00006742; WP:CE29459; WP:CE31225; WP:CE34591; WP:CE34980; XD330 WormBase description: unc-2 encodes a calcium channel alpha subunit required for desensitization to dopamine, normal flexion and speed during movement, normally low sensitivity of whole animals to serotonin, and neuronal migrations promoted by humoral serotonin; UNC-2 is orthologous to human CACNA1A (OMIM:601011, mutated in familiar hemiplegic migraine or episodic ataxia 2) and to Drosophila CACOPHONY; UNC-2 is expressed primarily in motor neurons, several sensory neurons, and HSN and VC neurons controlling egg-laying.
T24F1.6 T24F1.6 P W All gene names: tag-180; T24F1.6; 2L614; CE36207; CE36208; WBGene00007041; WBGene00011998; WP:CE36207; WP:CE36208 WormBase description: calcium channel alpha-2 subunit
T28F2.5 T28F2.5 P W All gene names: ccb-1; T28F2.5; 1E210; CE39788; NM_058792; WBGene00000368; WP:CE39788 WormBase description: ccb-1 encodes a homolog of the beta subunits of dihydropyridine sensitive L-type calcium channels that, in RNAi screens, is dispensable for viability or grossly normal morphology; a mutant allele of ccb-1 exists, but its phenotype has not yet been described. WormBase CDS description: calcium channel subunit
Y67D8C.10 Y67D8C.10 P W All gene names: mca-3; Y67D8A_367.A; Y67D8C.10; 4D868; CE28372; CE28373; CE31664; NM_067893; WBGene00003153; WP:CE28372; WP:CE28373; WP:CE31664
ZC21.2 ZC21.2 P W All gene names: trp-1; ZC21.2; 3J631; CE33009; CE39997; NM_066480; TRPL_CAEEL; WBGene00006614; WP:CE33009; WP:CE39997; strpc1 WormBase description: trp-1 encodes a predicted transmembrane protein with similarity to transient receptor potential (TRP) ion channels; a TRP-1::GFP reporter fusion is expressed in motor neurons, interneurons, vulval and intestinal muscles, and the BAG sensory neuron; as loss of trp-1 activity via deletion mutation or large-scale RNAi results in no obvious defects, the precise role of trp-1 in C. elegans development and/or behavior is not yet known.