PauliF et al 2006, ST5 commonly expressed genes, 510 genes

Gene list file name:PauliF2006_ST5_510_common-genes
Type of gene identifier:MA primer pair (sjj)
Description:PauliF et al 2006, Sup. Table 5. 510 genes commonly expressed in the intestine, muscle and germline. http://elegans.bcgsc.ca/perl/eprofile/index  
Organism:Caenorhabditis elegans (nematode)
Gene list type:Experimental

Gene name             Source Gene ID          Annotation                                                  Date       Added by    

B0025.2 B0025.2 P W All gene names: csn-2; B0025.2; B0025.2.1; B0025.2.2; B0025.2.3; 1G601; CE27562; CSN2_CAEEL; NM_059339; WBGene00000814; WP:CE27562 WormBase description: csn-2 encodes a homolog of COP9 signalosome complex subunit 2 that affects embryonic viability and growth rate.
B0035.4 B0035.4 P W All gene names: tag-317; B0035.4; B0035.4.1; B0035.4.2; B0035.4.3; 4M79; 4M81; CE05162; PFD4_CAEEL; WBGene00007107; WP:CE05162 WormBase description: paramyosin like
B0041.5 B0041.5 P W All gene names: B0041.5; 1F218; CE29527; WBGene00015009; WP:CE29527
B0205.8 B0205.8 P W All gene names: B0205.8; 1L306; CE17322; WBGene00015022; WP:CE17322
B0238.11 B0238.11 P W All gene names: B0238.11; B0238.11.1; B0238.11.2; 5F747; CE07701; WBGene00015075; WP:CE07701
B0285.3 B0285.3 P W All gene names: B0285.3; 3F432; CE00667; WBGene00007136; WP:CE00667; YKG3_CAEEL
B0303.15 B0303.15 P W All gene names: B0303.15; 3J807; CE00004; RM11_CAEEL; WBGene00015133; WP:CE00004 WormBase description: Ribosomal protein L11
B0334.4 B0334.4 P W All gene names: B0334.4; 2L787; CE02936; WBGene00007144; WP:CE02936 WormBase description: Yeast hypothetical protein L8167.12 like
B0336.7 B0336.7 P W All gene names: B0336.7; B0336.7b.1; B0336.7b.2; 3G784; CE29546; CE37741; Q10930_CAEEL; WBGene00015147; WP:CE29546; WP:CE37741
B0432.2 B0432.2 P W All gene names: B0432.2; 2A581; CE07740; WBGene00015184; WP:CE07740 WormBase description: djr-1.1 encodes an ortholog of DJ-1 (OMIM:602533, mutated in early-onset Parkinson disease); DJR-1.1 is required for resistance to rotenone, a mitochondrial complex I inhibitors that mimics Parkinson disease (PD); djr-1.1(RNAi) animals are partly rescued from PD-like sensitivity by D-beta-hydroxybutyrate or tauroursodeoxycholic acid, and fully rescued by both; by orthology with DJ-1, DJR-1.1 may promote stability of the transcription factors SKN-1 or SKNR-1 (homologs of mammalian NFE2L2).
B0464.5 B0464.5 P W All gene names: rsk-1; spk-1; srk-1; B0464.5; B0464.5b.1; B0464.5b.2; B0464.5c.1; B0464.5c.2; 3K551; CE20457; CE36373; CE36580; NM_066679; SPK1_CAEEL; WBGene00004980; WP:CE20457; WP:CE36373; WP:CE36580 WormBase description: spk-1 encodes a serine/threonine kinase orthologous to the highly conserved serine/arginine-rich protein kinases (SRPKs) that phosphorylate SR proteins, essential components of the pre-mRNA splicing machinery; SPK-1, required for embryogenesis and germline development, can directly bind and phosphorylate RSP-3 (CeSF2/ASF), an SR splicing factor homolog; SPK-1 is expressed predominantly in the adult germline; SPK-1 is homologous to human RSK2, which when mutated leads to Coffin-Lowry syndrome (OMIM:303600). WormBase CDS description: Eukaryotic protein kinase domain
B0491.7 B0491.7 P W All gene names: B0491.7; 2L641; CE02109; WBGene00007194; WP:CE02109 WormBase description: B0491.7 encodes a putative diphthine synthase orthologous to S. cerevisiae DPH5; DPH5 is an S-adenosylmethionine:EF-2 methyltransferase required for the enzymatic conversion of 3-amino-3-carboxypropyl-histidine to diphthine; DPH5 adds at least the last two of the three methyl groups present in diphthine, and is homologous to bacterial AdoMet:uroporphyrinogen III methyltransferases. WormBase CDS description: diphthine synthase
B0513.3 B0513.3 P W All gene names: rpl-29; B0513.3; B0513.3.1; B0513.3.2; 4O647; CE15559; NM_070270; WBGene00004443; WP:CE15559 WormBase description: rpl-29 encodes a large ribosomal subunit L29 protein; by homology, RPL-29 is predicted to function in protein biosynthesis; in C. elegans, loss of rpl-29 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities. WormBase CDS description: 60S ribosomal protein L29
C01A2.5 C01A2.5 P W All gene names: C01A2.5; 1N977; CE07787; WBGene00007217; WP:CE07787 WormBase description: S.pombe hypothetical protein C1D4.09C like
C01B12.8 C01B12.8 P W All gene names: C01B12.8; CE07796; NM_061235; WBGene00015291; WP:CE07796
C01F1.2 C01F1.2 P W All gene names: C01F1.2; 2E591; CE06743; WBGene00015297; WP:CE06743 WormBase description: C01F1.2 is orthologous to the human gene SCO (CYTOCHROME OXIDASE DEFICIENT, YEAST) HOMOLOG 1 (SCO1; OMIM:603644), which when mutated leads to early-onset hepatic failure; the C01F1.2 protein is predicted to be mitochondrial with 68% accuracy.
C01F6.8 C01F6.8 P W All gene names: icl-1; C01F6.8; 4J860; CE17360; CE30069; ICln; WBGene00002046; WP:CE17360; WP:CE30069 WormBase description: The icl-1 gene encodes, through alternative splicing, two alternative forms (ICL-1A, or 'IClnN1', and ICL-1B, or 'IClnN2'), with distinct electrophysiological properties, of an anion channel homolog. WormBase CDS description: nucleotide-sensitive chloride ion channel
C02F4.1 C02F4.1 P W All gene names: ced-5; C02F4.1; 4L257; CE24779; NM_069537; WBGene00000419; WP:CE24779 WormBase description: The ced-5 gene a homolog of the human protein DOCK180 that is required for the cell engulfment stage of programmed cell death. WormBase CDS description: DOCK180 protein
C02F5.9 C02F5.9 P W All gene names: pbs-6; C02F5.9; C02F5.9.1; C02F5.9.2; 3I332; 3J332; CE26745; NM_066405; PSB1_CAEEL; WBGene00003952; WP:CE26745 WormBase description: The pbs-6 gene encodes a homolog of mammalian PSMB1. WormBase CDS description: Proteasome component C5
C03D6.8 C03D6.8 P W All gene names: rpl-24.2; C03D6.8; C03D6.8.1; C03D6.8.2; 1K245; CE05202; NM_060171; RLP24_CAEEL; WBGene00004437; WP:CE05202 WormBase description: rpl-24.2 encodes a large ribosomal subunit L24 protein paralog; its orthologs include ribosomal protein L30 isologs from mammals and 'Ribosomal Like Protein 24' (Rlp24p) from S. cerevisiae; it therefore appears to actually represent an ancient paralogy between two varieties of eukaryotic L24 protein. WormBase CDS description: ribosomal protein
C04C3.3 C04C3.3 P W All gene names: C04C3.3; C04C3.3.1; C04C3.3.2; 4E167; CE27647; ODPB_CAEEL; WBGene00015413; WP:CE27647 WormBase description: pyruvate dehydrogenase
C04F12.7 C04F12.7 P W All gene names: C04F12.7; 1K272; CE19680; WBGene00007301; WP:CE19680
C04G2.8 C04G2.8 P W All gene names: C04G2.8; 4K876; CE05216; WBGene00007307; WP:CE05216
C04H5.1 C04H5.1 P W All gene names: C04H5.1; 2O821; CE15587; TR112_CAEEL; WBGene00007312; WP:CE15587
C05D11.10 C05D11.10 P W All gene names: C05D11.10; 3H520; CE01129; MRPS17; WBGene00015487; WP:CE01129; YPDA_CAEEL
C06A8.4 C06A8.4 P W All gene names: skr-17; C06A8.4; 2I75; CE02455; NM_063237; WBGene00004823; WP:CE02455 WormBase description: skr-17 encodes a homolog of Skp1 in S. cerevisiae, a core component of the SCF (Skp1p, Cullin, F-box) ubiquitin-ligase complex that facilitates ubiquitin-mediated protein degradation; SKR-17 has no known function in vivo, since skr-17(RNAi) animals are at least superficially normal, and SKR-17 does not appear to interact in vitro with any of the C. elegans cullin homologs.
C06E1.11 C06E1.11 P W All gene names: C06E1.11; 3J704; CE00056; WBGene00015526; WP:CE00056; YKQA_CAEEL
C06E7.3 C06E7.3 P W All gene names: C06E7.3; C06E7.3b.1; C06E7.3b.2; C06E7.3b.3; C06E7.3b.4; 4G610; CE03959; CE33517; METL_CAEEL; WBGene00015540; WP:CE03959; WP:CE33517 WormBase description: S-adenosylmethionine synthetase
C06G3.11 C06G3.11 P W All gene names: tin-9.1; C06G3.11; C06G3.11b.1; C06G3.11b.2; 4H808; CE07987; CE33518; TIM9_CAEEL; WBGene00006572; WP:CE07987; WP:CE33518; tim9a; tim9b WormBase description: tin-9 encodes a member of the Tim10/DDP family of zinc finger proteins, a family of proteins typically involved in mitochondrial protein import, and localized to the mitochondrial intermembrane space.
C06G4.4 C06G4.4 P W All gene names: C06G4.4; 3J64; CE00549; WBGene00015558; WP:CE00549; YKR4_CAEEL
C07A9.2 C07A9.2 P W All gene names: C07A9.2; C07A9.2.1; C07A9.2.2; 3J784; 3K784; BUD31_CAEEL; CE00499; WBGene00007400; WP:CE00499 WormBase description: G10 protein
C07E3.2 C07E3.2 P W All gene names: C07E3.2; C07E3.2.1; C07E3.2.2; 2K630; CE15606; NOC2L_CAEEL; WBGene00007413; WP:CE15606 WormBase description: pro-2 encodes the C. elegans ortholog of Saccharomyces cerevisiae Noc2p, which is required for intranuclear ribosome maturation and transport; in C. elegans, pro-2 activity is essential for larval growth, somatic gonad development, regulation of germline development and proliferation, and hence, fertility; by virtue of its similarity to Noc2p, PRO-2 is predicted to be a component of two heterodimeric intranuclear complexes that associate with, and aid in maturation of, different preribosomal particles.
C07G1.4 C07G1.4 P W All gene names: wsp-1; C07G1.4; 4I954; CE32572; CE32573; NM_171393; NM_171394; WBGene00006957; WP:CE32572; WP:CE32573 WormBase description: wsp-1 encodes a homolog of human WASP that interacts with Arp2/3 and is required for hypodermal cell migration during morphogenesis (ventral enclosure); when mutated, human WASP leads to Wiskott-Aldrich syndrome (OMIM:301000).
C07H6.1 C07H6.1 P W All gene names: lig-4; C07H6.1; 3I613; CE34522; NM_066252; WBGene00002986; WP:CE34522
C07H6.4 C07H6.4 P W All gene names: C07H6.4; 3I591; CE00755; WBGene00015581; WP:CE00755 WormBase description: Probable RNA binding protein
C08B11.5 C08B11.5 P W All gene names: sap-49; C08B11.5; C08B11.5.1; C08B11.5.2; C08B11.5.3; C08B11.5.4; 2I326; CE36374; SF3B4_CAEEL; WBGene00004723; WP:CE36374 WormBase description: Poly(A) RNA binding protein
C08F8.1 C08F8.1 P W All gene names: C08F8.1; 4L915; CE05248; PFD1_CAEEL; WBGene00007443; WP:CE05248
C09G4.3 C09G4.3 P W All gene names: cks-1; dom-6; C09G4.3; 4J279; CE03980; CKS1_CAEEL; NM_069056; WBGene00001051; WP:CE03980 WormBase description: A homolog of Cks/Suc1, a highly conserved member of the eukaryotic cell cycle machinery that affects both meiosis and mitosis and has a role in the inactivation of the M-phase promoting factor (MPF) during early embryogenesis. WormBase CDS description: cyclin-dependent kinase regulatory subunit
C10G11.9 C10G11.9 P W All gene names: C10G11.9; 1G850; CE08088; WBGene00015689; WP:CE08088
C14A4.5 C14A4.5 P W All gene names: crn-5; C14A4.5; 2K883; CE02146; NM_063883; WBGene00000798; WP:CE02146 WormBase description: Prokaryotic ribonuclease PH
C15H11.8 C15H11.8 P W All gene names: C15H11.8; 5O904; CE08185; WBGene00007616; WP:CE08185 WormBase description: DNA-directed RNA polymerase I like
C15H11.9 C15H11.9 P W All gene names: C15H11.9; C15H11.9.1; C15H11.9.2; 5O906; CE08186; RRS1_CAEEL; WBGene00007617; WP:CE08186 WormBase description: Human HA0609 protein like
C16A11.5 C16A11.5 P W All gene names: C16A11.5; 2E513; CE34689; WBGene00015818; WP:CE34689
C16A3.3 C16A3.3 P W All gene names: C16A3.3; 3H477; CE27690; NM_065997; WBGene00015808; WP:CE27690
C16A3.6 C16A3.6 P W All gene names: C16A3.6; 3H469; CE04006; WBGene00015811; WP:CE04006
C16C10.4 C16C10.4 P W All gene names: C16C10.4; 3F261; CE01495; SAP18_CAEEL; WBGene00007625; WP:CE01495
C16C10.7 C16C10.7 P W All gene names: rnf-5; C16C10.7; 3F254; CE01498; NM_065429; RNF5_CAEEL; WBGene00004381; WP:CE01498 WormBase description: This gene encodes a homolog of mammalian RNF5, a C3HC4 (RING-finger) zinc-finger protein. WormBase CDS description: Zinc finger, C3HC4 type (RING finger)
C17F4.5 C17F4.5 P W All gene names: C17F4.5; 2D538; CE27075; WBGene00015912; WP:CE27075 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
C17G10.2 C17G10.2 P W All gene names: C17G10.2; 2F885; CE29583; WBGene00015916; WP:CE29583 WormBase description: TPR domain
C17H12.13 C17H12.13 P W All gene names: C17H12.13; 4H543; CE37201; WBGene00015938; WP:CE37201
C18D11.4 C18D11.4 P W All gene names: rsp-8; C18D11.4; C18D11.4.1; C18D11.4.2; 3M919; CE18515; NM_067132; WBGene00004705; WP:CE18515 WormBase description: RNA recognition motif. (aka RRM, RBD, or RNP domain)
C23H3.3 C23H3.3 P W All gene names: C23H3.3; 2A349; CE08322; P91080_CAEEL; WBGene00016019; WP:CE08322
C24A11.9 C24A11.9 P W All gene names: tag-134; C24A11.9; 1F982; CE29183; NM_059187; WBGene00000761; WP:CE29183 WormBase description: coq-1 encodes a putative hexaprenyl pyrophosphate synthetase, orthologous to S. cerevisiae COQ1; COQ-1 is required for ubiquinone (coenzyme Q9) biosynthesis and for normally short lifespan; coq-1 mutants have slowed pharyngeal pumping, and eventually arrest as paralysed larvae before dying; coq-1(RNAi) animals have reduced levels of coenzyme Q9 and superoxide, and have abnormally long lifespans; coq-1 mutants are not rescued by dietary coenzyme Q. WormBase CDS description: hexaprenyl pyrophosphate synthetase
C24D10.4 C24D10.4 P W All gene names: C24D10.4; 4F925; CE16876; WBGene00016055; WP:CE16876
C24D10.6 C24D10.6 P W All gene names: C24D10.6; 4F924; CE16878; WBGene00016057; WP:CE16878
T05C3.5 C24G6.5 P W
C24G6.8 C24G6.8 P W All gene names: C24G6.8; C24G6.8.1; C24G6.8.2; C24G6.8.3; 5G16; CE17464; PTH2_CAEEL; WBGene00016062; WP:CE17464
C25A1.1 C25A1.1 P W All gene names: C25A1.1; 1K739; CE08366; WBGene00007705; WP:CE08366
C25A1.6 C25A1.6 P W All gene names: C25A1.6; 1K757; CE27803; NOLA3_CAEEL; WBGene00007708; WP:CE27803
C25A8.2 C25A8.2 P W All gene names: C25A8.2; 4H775; CE31313; WBGene00016083; WP:CE31313
C25D7.10 C25D7.10 P W All gene names: C25D7.10; CE27731; WBGene00007720; WP:CE27731
C25G4.3 C25G4.3 P W All gene names: C25G4.3; 4N210; CE05304; WBGene00007731; WP:CE05304
C25G4.7 C25G4.7 P W All gene names: C25G4.7; 4N223; CE05308; WBGene00007734; WP:CE05308
C25H3.3 C25H3.3 P W All gene names: C25H3.3; 2F983b; CE32140; WBGene00016112; WP:CE32140
C26F1.4 C26F1.4 P W All gene names: rps-30; C26F1.4; C26F1.4.1; C26F1.4.2; C26F1.4.3; 5I257; CE06878; NM_072606; WBGene00004499; WP:CE06878 WormBase description: rps-30 encodes two proteins, a small ribosomal subunit S30 protein and ubiquitin, which is cleaved from the ribosomal protein posttranslationally; by homology, S30 is predicted to function in protein biosynthesis and ubiquitin in protein degradation; in C. elegans, loss of rps-30 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities. WormBase CDS description: ribosomal protein/ubiquitin-like protein
C27B7.1 C27B7.1 P W All gene names: spr-2; C27B7.1; 4J657; CE03030; CE27804; NM_069142; SPR2_CAEEL; WBGene00005007; WP:CE03030; WP:CE27804 WormBase description: spr-2 encodes the C. elegans ortholog of the Drosophila and mammalian SET proteins (OMIM:600960, translocation breakpoint in human SET is associated with acute myeloid leukemia); SPR-2 is predicted to be a member of the SET protein complex that functions in chromatin remodeling, DNA repair, and transcriptional regulation; in C. elegans, SPR-2 may function to regulate the activity and/or levels of the presenilin proteins encoded by sel-12 and hop-1, as mutations in spr-2 suppress mutations in sel-12 in a hop-1-dependent manner; spr-2 is detected in the nuclei of all cells at several developmental stages, including the L3 larval stage.
C27D6.3 C27D6.3 P W All gene names: C27D6.3; 2F464; CE01813; WBGene00016161; WP:CE01813; YQ93_CAEEL WormBase description: MST101-2 protein (Fruit Fly)
T23B5.3 C27D8.5 P W
C27H5.3 C27H5.3 P W All gene names: C27H5.3; C27H5.3.1; C27H5.3.2; C27H5.3.3; 2H445; CE27099; WBGene00016173; WP:CE27099 WormBase description: Probable RNA binding protein
C28H8.3 C28H8.3 P W All gene names: C28H8.3; C28H8.3.1; C28H8.3.2; C28H8.3.3; 3H3; CE29195; WBGene00016194; WP:CE29195; YP93_CAEEL
C28H8.4 C28H8.4 P W All gene names: C28H8.4; 3G997; CE01826; ERD22_CAEEL; WBGene00016195; WP:CE01826 WormBase description: ER lumen protein retaining receptor
C30B5.2 C30B5.2 P W All gene names: C30B5.2; 2G487; CE31889; CE31890; WBGene00016244; WP:CE31889; WP:CE31890; YTO2_CAEEL
C30C11.1 C30C11.1 P W All gene names: C30C11.1; 3J539; CE00100; RM32_CAEEL; WBGene00016249; WP:CE00100
C30C11.2 C30C11.2 P W All gene names: rpn-3; C30C11.2; C30C11.2.1; C30C11.2.2; 3J537; CE00101; NM_066468; PSMD3_CAEEL; WBGene00004460; WP:CE00101 WormBase description: Diphenol oxidase A2
C30C11.4 C30C11.4 P W All gene names: C30C11.4; C30C11.4.1; C30C11.4.2; 3J534; CE00103; WBGene00016250; WP:CE00103; YLA4_CAEEL WormBase description: Msi3p
C30F12.4 C30F12.4 P W All gene names: C30F12.4; 1H548; CE16884; WBGene00016263; WP:CE16884
C30H6.8 C30H6.8 P W All gene names: C30H6.8; 4S327; CE15652; WBGene00007825; WP:CE15652 WormBase description: Thioredoxins
C32E8.2 C32E8.2 P W All gene names: rpl-13; C32E8.2; C32E8.2a.1; C32E8.2a.2; C32E8.2a.3; C32E8.2b.1; C32E8.2b.2; 1E357; CE08526; CE33562; RL13_CAEEL; WBGene00004425; WP:CE08526; WP:CE33562 WormBase description: rpl-13 encodes a large ribosomal subunit L13 protein.
C32E8.5 C32E8.5 P W All gene names: C32E8.5; 1E351; CE08529; WBGene00016323; WP:CE08529
C34B2.5 C34B2.5 P W All gene names: C34B2.5; 1L252; CE16893; WBGene00016390; WP:CE16893
C34C12.8 C34C12.8 P W All gene names: C34C12.8; 3E551; CE03057; GRPE_CAEEL; WBGene00007927; WP:CE03057 WormBase description: GRPE protein
C34D4.12 C34D4.12 P W All gene names: cyn-12; cyp-12; C34D4.12; 4H894; CE17506; NM_068717; WBGene00000888; WP:CE17506 WormBase description: cyp-12 encodes a member of the cyclophilin family.
C35D10.5 C35D10.5 P W All gene names: C35D10.5; 3F951; CE01199; WBGene00016442; WP:CE01199
C36A4.4 C36A4.4 P W All gene names: C36A4.4; C36A4.4.1; C36A4.4.2; 3E932; CE27831; UAP1_CAEEL; WBGene00007965; WP:CE27831
C37C3.3 C37C3.3 P W All gene names: phi-63; C37C3.3; 5I331; CE39687; WBGene00016497; WP:CE39687
C41H7.6 C41H7.6 P W All gene names: C41H7.6; 2D291; CE08677; WBGene00016576; WP:CE08677
C42C1.12 C42C1.12 P W All gene names: C42C1.12; 4N46; CE16918; WBGene00016590; WP:CE16918
C43E11.4 C43E11.4 P W All gene names: EF-Tu2; tufm-2; C43E11.4; 1E817; CE32610; WBGene00007001; WBGene00016604; WP:CE32610 WormBase description: elongation factor Tu
C45G9.2 C45G9.2 P W All gene names: C45G9.2; 3G159; CE29722; WBGene00016674; WP:CE29722; YQI2_CAEEL
C47E8.5 C47E8.5 P W All gene names: daf-21; tax-3; C47E8.5; C47E8.5.1; C47E8.5.2; C47E8.5.3; 5P167; CE05441; HSP90_CAEEL; NM_074225; WBGene00000915; WP:CE05441 WormBase description: daf-21 encodes a member of the Hsp90 family of molecular chaperones; DAF-21 activity is required for larval development, negative regulation of dauer larva formation, and a number of specific chemosensory behaviors, such as the response to chemicals and odorants detected by the ASE and AWC sensory neurons; a daf-21 sensory defect can be rescued by a cyclic GMP analogue, suggesting that, in regulating chemosensory behaviors, DAF-21 acts at a similar point as the DAF-11 guanylyl cyclase; down-regulation of daf-21 via RNAi results in a small but reproducible reduction in age-1 life span, suggesting that daf-21 is part of a chaperone network required for the extended life span seen in age-1 mutant animals. WormBase CDS description: heat shock protein (HSP90)
C48B6.2 C48B6.2 P W All gene names: C48B6.2; C48B6.2.1; C48B6.2.2; 1H493; CE08804; WBGene00016740; WP:CE08804; YS4L_CAEEL WormBase description: ribosomal protein
C48E7.3 C48E7.3 P W All gene names: lpd-2; C48E7.3; 1G831; CE29953; NM_059405; WBGene00003059; WP:CE29953 WormBase description: lpd-2 encodes a predicted transcription factor with homology to transcription factors of the CCAAT/Enhancer Binding Protein family (C/EBPA and B, OMIM:116897, 189965, associated with the regulation of mammalian adipocyte differentiation); in C. elegans, LPD-2 activity is required for normal lipid metabolism and wild-type levels of lipogenic enzyme expression, as well as for larval development; in addition, LPD-2 may be part of a conserved pathway regulating lipogenesis, as LPD-2 appears to positively regulate expression of sbp-1, which encodes the C. elegans Sterol Regulatory Element Binding Protein (SREBP) homolog, a basic helix-loop-helix-type transcription factor also required for normal lipid metabolism and larval development.
C49H3.8 C49H3.8 P W All gene names: C49H3.8; 4I664; CE04234; WBGene00016793; WP:CE04234 WormBase description: actin-like protein
C49H3.9 C49H3.9 P W All gene names: C49H3.9; 4I672; CE27873; WBGene00016794; WP:CE27873
C50B8.3 C50B8.3 P W All gene names: C50B8.3; 5O46; CE08883; CIA30_CAEEL; WBGene00008225; WP:CE08883
Y79H2A.3 C51G7.D P W
C52E4.3 C52E4.3 P W All gene names: snr-4; C52E4.3; C52E4.3.1; C52E4.3.2; 5M460; CE08945; NM_073603; SMD2_CAEEL; WBGene00004917; WP:CE08945 WormBase description: small nuclear ribonucleoprotein D2 like
C53A5.3 C53A5.3 P W All gene names: gon-10; hda-1; C53A5.3; C53A5.3.1; C53A5.3.2; 5P7; CE08952; HDA1_CAEEL; NM_074198; WBGene00001834; WP:CE08952 WormBase description: The hda-1 gene encodes a histone deacetylase 1, similar to histone deacetylases RPD3 from yeast and fly; maternal and zygotic expression of hda-1 is required for embryonic viability, and zygotic expression of hda-1 is also required for gonadogenesis and vulval development. WormBase CDS description: Yeast RPD3 protein like
C53D5.6 C53D5.I P W
C53H9.2 C53H9.2 P W All gene names: C53H9.2; C53H9.2b.1; C53H9.2b.2; C53H9.2b.3; C53H9.2b.4; C53H9.2c.1; C53H9.2c.2; C53H9.2c.3; C53H9.2c.4; 1C307; CE08963; CE33575; CE39907; WBGene00016907; WP:CE08963; WP:CE33575; WP:CE39907 WormBase description: C53H9.2 encodes at least three protein isoforms orthologous to the GTP-binding proteins human GNL1 (HSR1; OMIM:143024) and murine MMR1, as well as LSG1 in S. cerevisiae and many other eukaryotic and bacterial proteins; one alternative transcription unit of the C53H9.2 locus, C53H9.2a, has a natural nonsense transcript that is up-regulated in vivo by smg[-] mutations, indicating that C53H9.2 is a natural substrate for SMG-mediated nonsense suppresssion; C53H9.2 is required in mass RNAi assays for embryonic viability, normally rapid growth, and early embryonic nuclear positioning; since several other natural mRNA substrates of SMG suppression (e.g., rpl-3, rpl-8, rpl-10a, rpl-12) have protein products that are involved in translation, C53H9.2's protein products may function in translation as well, an inference supported by the observed role of LSG1 in cytoplasmic 60S ribosomal subunit biogenesis.
C56A3.5 C56A3.5 P W All gene names: C56A3.5; 5O31; CE09033; WBGene00008344; WP:CE09033
C56C10.8 C56C10.8 P W All gene names: icd-1; C56C10.8; C56C10.8.1; C56C10.8.2; 2G878; BTF3_CAEEL; CE02573; NM_062935; WBGene00002045; WP:CE02573 WormBase description: Transcription factor BTF3 (human)
CD4.3 CD4.3 P W All gene names: CD4.3; CD4.3.1; CD4.3.2; 5G73; CE16951; WBGene00016989; WP:CE16951
CD4.4 CD4.4 P W All gene names: CD4.4; 5G71; CE16952; WBGene00016990; WP:CE16952
CD4.6 CD4.6 P W All gene names: pas-6; CD4.6; CD4.6.1; CD4.6.2; 5G64; CE16954; NM_072071; PSA1_CAEEL; WBGene00003927; WP:CE16954 WormBase description: pas-6 encodes a type 1 alpha subunit of the 26S proteasome's 20S protease core particle (CP); PAS-6 is required for embryonic, larval, and germline development and by homology, is predicted to comprise the outer rings of the proteasome and to play a role in selective degradation of ubiquitinated proteins during development; in vitro, PAS-6 interacts with BRP-1, a glutamine/asparagine (Q/N)-rich domain-containing protein conserved amongst nematodes, and with other members of the proteasome. WormBase CDS description: protease
D1037.4 D1037.4 P W All gene names: rab-8; D1037.4; 1E252; CE30373; NM_058798; WBGene00004272; WP:CE30373; rab8 WormBase description: rab-8 encodes a rab related protein of the Ras GTPase superfamily that affects ovarian morphology and function, thereby affecting fertility; acts downstream of let-60 with respect to vulval development based on genetic analysis. WormBase CDS description: RAS-related protein
D1054.1 D1054.1 P W All gene names: D1054.1; 5L248; CE35445; WBGene00008370; WP:CE35445 WormBase description: Human GS2 protein like
D1054.2 D1054.2 P W All gene names: pas-2; tag-166; D1054.2; 5L251; CE05521; NM_073349; PSA2_CAEEL; WBGene00003923; WP:CE05521 WormBase description: pas-2 encodes a proteasome subunit with highest similarity to vertebrate proteasome alpha 2 subunits. WormBase CDS description: proteasome component C3
D1054.3 D1054.3 P W All gene names: D1054.3; D1054.3.1; D1054.3.2; 5L253; CE05522; WBGene00008371; WP:CE05522
D2007.4 D2007.4 P W All gene names: D2007.4; 3J235; CE00129; WBGene00017044; WP:CE00129; YLM4_CAEEL
D2030.3 D2030.3 P W All gene names: D2030.3; D2030.3.1; D2030.3.2; 1I154; CE09080; WBGene00008413; WP:CE09080
Y108G3AL.7 DC2.4 P W
DY3.1 DY3.1 P W All gene names: tim-13; tin-13; DY3.1; 1J336; CE15745; NM_059969; TIM13_CAEEL; WBGene00006574; WP:CE15745; tim13
E02H1.1 E02H1.1 P W All gene names: E02H1.1; 2J880; CE30642; DIMT1_CAEEL; WBGene00008455; WP:CE30642 WormBase description: rRNA methyltransferase
E02H1.5 E02H1.5 P W All gene names: E02H1.5; 2J885; CE01540; WBGene00008457; WP:CE01540; YQN5_CAEEL
E02H1.6 E02H1.6 P W All gene names: E02H1.6; 2J887; CE28286; KAD6_CAEEL; WBGene00008458; WP:CE28286 WormBase description: E02H1.6 encodes an ortholog of human TAF9 (OMIM:600822; also known as AK6, adrenal gland protein AD-004 like protein, ADLP) and of S. cerevisiae Fap7p; like its human ortholog, E02H1.6 is nuclear, and is predicted to likewise be a TATA box binding protein (TBP)-associated factor mediating activation of RNA polymerase II; E02H1.6 prefers ATP and dATP as phosphate donors; E02H1.6's biochemical activity is unusual, since it also prefers AMP and dAMP as substrates, and tolerates CMP, TMP and shikimate acid as substrates as well; since yeast Fap7p promotes pre-rRNA cleavage, E02H1.6 may be multifunctional; in RNAi assays, E02H1.6 is required for normally fast growth. WormBase CDS description: ATP binding protein
E03H12.10 E03H12.10 P W All gene names: ssp-9; E03H12.10; E03H12.10.1; E03H12.10.2; 4F758; CE09149; NM_068296; WBGene00006038; WP:CE09149
E03H12.5 E03H12.5 P W All gene names: E03H12.5; 4F743; CE09144; WBGene00017112; WP:CE09144
E04A4.5 E04A4.5 P W All gene names: E04A4.5; 4F508; CE16966; TIM17_CAEEL; WBGene00017119; WP:CE16966
EEED8.7 EEED8.7 P W All gene names: rsp-4; srp-2; EEED8.7; 2F678; CE01891; CE27910; CeSC35; NM_062612; NM_062613; RSP4_CAEEL; WBGene00004701; WP:CE01891; WP:CE27910 WormBase description: splicing factor SC35
F01F1.2 F01F1.2 P W All gene names: F01F1.2; 3G969; CE26886; WBGene00017159; WP:CE26886
F01F1.8 F01F1.8 P W All gene names: cct-6; F01F1.8; F01F1.8a.1; F01F1.8a.2; F01F1.8b.1; F01F1.8b.2; F01F1.8b.3; 3G944; CE01234; CE30647; NM_171135; NM_171136; TCPZ_CAEEL; WBGene00000381; WP:CE01234; WP:CE30647 WormBase description: eukaryotic cytosolic chaperonin; affects viability and fertility, and is expressed in various muscle and neuronal cells: near the pharynx, near the anal sphincter, in the ventral nerve cord and the nerve ring; occasionally the expression is visible in hypodermal cells and in some vulval cells.
C36C9.5 F07G6.4 P W
F08B6.1 F08B6.1 P W All gene names: F08B6.1; F08B6.F; 1H339; CE39717; WBGene00017239; WP:CE39717
F10C5.1 F10C5.2 P W
F10E7.5 F10E7.5 P W All gene names: F10E7.5; 2H403; CE04360; WBGene00017347; WP:CE04360
F10E9.4 F10E9.4 P W All gene names: F10E9.4; 3J399; CE00148; WBGene00017356; WP:CE00148; YLU4_CAEEL
F10G7.3 F10G7.3 P W All gene names: asf-1; F10G7.3; F10G7.3.1; F10G7.3.2; 2E993; CE39722; WBGene00017368; WP:CE39722
F13G3.10 F13G3.10 P W All gene names: F13G3.10; CE17660; NM_059669; WBGene00008768; WP:CE17660
F13H6.1 F13H6.1 P W All gene names: F13H6.1; 5G841; CE30755; WBGene00017430; WP:CE30755 WormBase description: zinc-finger protein
F14H3.6 F14H3.6 P W All gene names: F14H3.6; 5Q538; CE23652; WBGene00008825; WP:CE23652
F15D4.2 F15D4.2 P W All gene names: F15D4.2; F15D4.2.1; F15D4.2.2; 2N507; CE09415; Q93510_CAEEL; WBGene00008859; WP:CE09415
F19B6.2 F19B6.2 P W All gene names: ufd-1; F19B6.2; 4N94; CE05667; CE23674; NM_069947; NM_069948; UFD1_CAEEL; WBGene00006733; WP:CE05667; WP:CE23674
F21C3.3 F21C3.3 P W All gene names: tag-202; F21C3.3; 1H856; CE05678; WBGene00009002; WP:CE05678; YHIT_CAEEL WormBase description: protein kinae C inhibitor 1 like
F21C3.5 F21C3.5 P W All gene names: F21C3.5; 1H860; CE05680; PFD6_CAEEL; WBGene00009004; WP:CE05680 WormBase description: Mouse KE2 protein like
Y54H5A.2 F21H11.4 P W
F22B5.1 F22B5.1 P W All gene names: arf-2; evl-20; F22B5.1; 2I735; ARF/2; ARFM_CAEEL; CE27425; NM_063378; WBGene00001358; WP:CE27425 WormBase description: evl-20 encodes a functional ortholog of human ADP-ribosylation factor-like protein 2 (ARL2; OMIM:601175), with evl-20(ar103) mutants being rescued by transgenic human ARL2 but not ARL1 or ARL3-7; EVL-20 is required for cortical microtubule formation during cytokinesis and morphogenesis; EVL-20 is required for vulval, gonadal, and male tail development, as well as for embryonic mitosis, hypodermal enclosure, and elongation; EVL-20 is expressed in migrating hypodermal embryonic cells, larval vulval and somatic gonad cells, larval and adult neurons, and adult male proctodeal cells, being subcellularly associated with both the cell cortex and astral microtubules. WormBase CDS description: GTP-binding ADP-ribosylation factor
F22B5.10 F22B5.10 P W All gene names: F22B5.10; F22B5.10.1; F22B5.10.2; 2I757; CE02196; WBGene00009045; WP:CE02196
F22B5.2 F22B5.2 P W All gene names: eif-3.G; F22B5.2; 2I733; CE02197; IF34_CAEEL; NM_063377; WBGene00001230; WP:CE02197 WormBase description: eif-3.G encodes a homolog of eukaryotic translation initiation factor 3, subunit 4 that affects embryonic viability, fertility, and growth. WormBase CDS description: RNA binding protein
F22D6.2 F22D6.2 P W All gene names: F22D6.2; F22D6.2.1; F22D6.2.2; 1H656; CE05683; WBGene00009050; WP:CE05683
F22D6.3 F22D6.3 P W All gene names: nrs-1; F22D6.3; F22D6.3a.1; F22D6.3a.2; 1H664; CE05684; SYNC_CAEEL; WBGene00003815; WP:CE05684 WormBase description: nrs-1 encodes an asparaginyl-tRNA synthetase that is required for embryonic viability and fertility WormBase CDS description: asparaginyl-tRNA synthetase
F22E5.9 F22E5.9 P W All gene names: F22E5.9; 2C927; CE09561; WBGene00017708; WP:CE09561
F23B2.6 F23B2.6 P W All gene names: aly-2; ref-2; F23B2.6; 4J913; CE09586; NM_069193; WBGene00000121; WP:CE09586 WormBase description: vimentin like
F23F1.1 F23F1.1 P W All gene names: F23F1.1; CE27996; WBGene00017742; WP:CE27996
F25B4.4 F25B4.4 P W All gene names: F25B4.4; 5G165; CE09622; WBGene00017767; WP:CE09622
F25G6.8 F25G6.8 P W All gene names: F25G6.8; F25G6.8.1; F25G6.8.2; 5J44; CE09644; SRP14_CAEEL; WBGene00017799; WP:CE09644
F25H2.4 F25H2.4 P W All gene names: F25H2.4; 1L129; CE09649; Q93568_CAEEL; WBGene00009118; WP:CE09649
F25H2.5 F25H2.5 P W All gene names: F25H2.5; F25H2.5.1; F25H2.5.2; F25H2.5.3; 1L130; CE09650; WBGene00009119; WP:CE09650 WormBase description: nucleoside diphosphate kinase
F25H5.6 F25H5.6 P W All gene names: F25H5.6; F25H5.6.1; F25H5.6.2; 1J734; CE29591; WBGene00009128; WP:CE29591
F26D11.1 F26D11.1 P W All gene names: F26D11.1; 5I463; CE30765; WBGene00017818; WP:CE30765 WormBase description: gluconokinase
F26E4.4 F26E4.4 P W All gene names: F26E4.4; 1K348; CE09688; WBGene00009159; WP:CE09688
F26F4.10 F26F4.10 P W All gene names: rrt-1; F26F4.10; F26F4.10a.1; F26F4.10a.2; F26F4.10b.1; F26F4.10b.2; 3G4; CE29495; CE37225; SYRC_CAEEL; WBGene00004679; WP:CE29495; WP:CE37225 WormBase description: rrt-1 encodes an arginyl-tRNA synthetase that affects embryonic viability and fertility
F26F4.6 F26F4.6 P W All gene names: F26F4.6; 3F980; CE29290; WBGene00017828; WP:CE29290
F26H11.2 F26H11.3 P W
F26H9.7 F26H9.7 P W All gene names: uev-3; F26H9.7; 1J887; CE09712; NM_060081; WBGene00006732; WP:CE09712 WormBase description: uev-3 encodes a ubiquitin-conjugating enzyme (UBC or E2) variant that contains the UBC motif, but lacks the critical active-site cysteine residue necessary for catalytic activity; as loss of UEV-3 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UEV-3 in C. elegans development and/or behavior is not yet known; based on similarity to Saccharomyces cerevisiae and human proteins, however, UEV-3 may play a role in cell cycle control or response to stress or DNA damage. WormBase CDS description: ubiquitin-conjugating enzyme
F27D4.4 F27D4.4 P W All gene names: F27D4.4; 1I303; CE36141; WBGene00009189; WP:CE36141 WormBase description: Yeast hypothetical protein YOR316OW like
F28C6.6 F28C6.6 P W All gene names: suf-1; F28C6.6; 2I895; CE03277; NM_063424; WBGene00006307; WP:CE03277 WormBase description: polyadenylation factor like
F28C6.7 F28C6.7A P W
F28C6.8 F28C6.8 P W All gene names: F28C6.8; 2I897; CE09746; WBGene00009207; WP:CE09746 WormBase description: MAP kinase phosphatase like
F28D1.2 F28D1.2 P W All gene names: F28D1.2; 4N140; CE05742; Q19872_CAEEL; WBGene00009212; WP:CE05742
F28D1.7 F28D1.7 P W All gene names: rps-23; F28D1.7; F28D1.7.1; F28D1.7.2; 4N154; CE05747; NM_069964; RS23_CAEEL; WBGene00004492; WP:CE05747 WormBase description: rps-23 encodes a small ribosomal subunit S23 protein; by homology, RPS-23 is predicted to function in protein biosynthesis; in C. elegans, RPS-23 activity is required for germline development, vulval morphogenesis, and the overall health of the animal. WormBase CDS description: ribosomal protein S23
F28F8.3 F28F8.3 P W All gene names: lsm-5; F28F8.3; F28F8.3.1; F28F8.3.2; 5Q49; CE09757; NM_074469; WBGene00003079; WP:CE09757 WormBase description: small nuclear ribonucleoprotein E (SNRNP-E) like
F29A7.6 F29A7.6 P W All gene names: F29A7.6; 2D42; CE09777; WBGene00017916; WP:CE09777; YF26_CAEEL
F29B9.10 F29B9.10 P W All gene names: F29B9.10; 4F422; CE09788; WBGene00017924; WP:CE09788
F29B9.2 F29B9.2 P W All gene names: F29B9.2; 4F429; CE09781; CE27145; WBGene00017920; WP:CE09781; WP:CE27145
F29B9.5 F29B9.5 P W All gene names: F29B9.5; CE28013; WBGene00017921; WP:CE28013
F30F8.7 F30F8.7 P W All gene names: F30F8.7; CE09818; WBGene00009275; WP:CE09818
F31C3.4 F31C3.4 P W All gene names: F31C3.4; 1P644; CE17733; WBGene00009286; WP:CE17733
F31D4.1 F31D4.1 P W All gene names: F31D4.1; 5V311; CE31921; WBGene00009289; WP:CE31921
F32A5.7 F32A5.7 P W All gene names: lsm-4; F32A5.7; 2H542; CE01277; LSM4_CAEEL; NM_063113; WBGene00003078; WP:CE01277 WormBase description: U6 small nuclear RNA-associated Sm-like protein LSm4
F32E10.6 F32E10.6 P W All gene names: F32E10.6; F32E10.6.1; F32E10.6.2; 4I344; CE04479; WBGene00017993; WP:CE04479
F33A8.1 F33A8.1 P W All gene names: let-858; F33A8.1; F33A8.1.1; F33A8.1.2; 2L317; CE17753; NM_063962; Q17336_CAEEL; WBGene00002957; WP:CE17753 WormBase description: let-858 encodes nucampholin, a highly conserved protein rich in acidic and basic residues that also shares some similarity to eukaryotic initiation factor eIF-4 gamma; LET-858 is required for early embryogenesis and tissue differentiation and is expressed ubiquitously throughout development; LET-858 localizes to nuclei where it overlaps, but is not restricted to, chromosomal regions; based upon its sequence and localization, LET-858 is likely to be involved in protein synthesis and/or RNA binding.
F33D11.11 F33D11.11 P W All gene names: F33D11.11; 1G446; CE09902; O44782_CAEEL; WBGene00018008; WP:CE09902
F33D4.5 F33D4.5 P W All gene names: F33D4.5; F33D4.5.1; F33D4.5.2; 4I472; CE29308; WBGene00017997; WP:CE29308
F33H2.3 F33H2.3 P W All gene names: F33H2.3; F33H2.3.1; F33H2.3.2; 1P627; AN321_CAEEL; CE17766; WBGene00009367; WP:CE17766 WormBase description: Leucine Rich Repeat (2 copies) (2 domains)
F35D11.4 F35D11.4 P W All gene names: F35D11.4; 2E893; CE32648; WBGene00018045; WP:CE32648
F35G12.11 F35G12.11 P W All gene names: F35G12.11; F35G12.11.1; F35G12.11.2; 3F683; CE36485; WBGene00009444; WP:CE36485
F35H10.6 F35H10.6 P W All gene names: F35H10.6; 4J65; CE38515; WBGene00018071; WP:CE38515
F36A2.8 F36A2.8 P W All gene names: F36A2.8; 1J389; CE32406; WBGene00009455; WP:CE32406 WormBase description: Drosophila sex-regulated protein janus like
F37C12.11 F37C12.11 P W All gene names: rps-21; F37C12.11; F37C12.11.1; F37C12.11.2; 3I278; CE30779; NM_066178; RS21_CAEEL; WBGene00004490; WP:CE30779 WormBase description: rps-21 encodes a small ribosomal subunit S21 protein; by homology, RPS-21 is predicted to function in protein biosynthesis; in C. elegans, RPS-21 activity is required for embryonic and germline development, as well as the overall health of the animal. WormBase CDS description: Ribosomal protein S21
Y92H12BR.8 F37F2.1 P W
F39B2.11 F39B2.11 P W All gene names: F39B2.11; 1P348; CE16016; MTX1_CAEEL; WBGene00009559; WP:CE16016
F39B2.2 F39B2.2 P W All gene names: mms-2; uev-1; F39B2.2; F39B2.2.1; F39B2.2.2; 1P383; CE16008; NM_061177; WBGene00006730; WP:CE16008 WormBase description: uev-1 encodes a ubiquitin-conjugating enzyme (UBC or E2) variant that contains the characteristic UBC motif, but lacks the critical active-site cysteine residue necessary for catalytic activity; as loss of UEV-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UEV-1 in C. elegans development and/or behavior is not yet known; UEV-1 does, however, interact with a number of proteins, such as UBC-13, that are likely involved in the response to DNA damage; thus, UEV-1 may play a role in ubiquitination and protein turnover in conjunction with DNA repair or the DNA damage checkpoint pathway.
F39H11.5 F39H11.5 P W All gene names: pbs-7; F39H11.5; F39H11.5.1; F39H11.5.2; 1J272; CE20761; NM_059953; WBGene00003953; WP:CE20761 WormBase description: pbs-7 encodes a B-type subunit of the 26S proteasome's 20S protease core particle; by homology, PBS-7 is predicted to function in ATP/ubiquitin-dependent nonlysosomal protein degradation; loss of pbs-7 activity via large-scale RNAi screens indicates that, in C. elegans, PBS-7 is required for normal movement and for embryonic, germline, and larval development. WormBase CDS description: Yeast NIP80 protein like
F40F11.3 F40F11.3 P W All gene names: F40F11.3; 4M354; CE05862; WBGene00009588; WP:CE05862
F40F8.9 F40F8.9 P W All gene names: lsm-1; F40F8.9; F40F8.9.1; F40F8.9.2; 2L417; CE05848; NM_063984; WBGene00003076; WP:CE05848 WormBase description: Yeast J0714 like
F40G9.2 F40G9.2 P W All gene names: F40G9.2; 3A809; CE19849; WBGene00018240; WP:CE19849
F41B5.1 F41B5.1 P W All gene names: F41B5.1; 5C733; WBGene00023284
F42A6.7 F42A6.7 P W All gene names: hrp-1; rbp-1; F42A6.7; F42A6.7a.1; F42A6.7a.2; F42A6.7a.3; F42A6.7b.1; F42A6.7b.2; F42A6.7b.3; F42A6.7b.4; 4E102; CE17059; CE29317; CE31510; CE39251; NM_067925; ROA1_CAEEL; WBGene00001999; WP:CE17059; WP:CE29317; WP:CE31510; WP:CE39251 WormBase description: The hrp-1 gene encodes a homolog of the human DRPLA gene (OMIM:125370), which when mutated leads to dentatorubral-pallidoluysian atrophy or to Haw River syndrome (OMIM:140340).
F42A9.6 F42A9.6 P W All gene names: F42A9.6; 4J371; CE34859; WBGene00018335; WP:CE34859
F43C1.3 F43C1.3 P W All gene names: F43C1.3; 3F334; CE37012; WBGene00009648; WP:CE37012
F43D2.1 F43D2.1 P W All gene names: F43D2.1; 5P93; CE38186; WBGene00009650; WP:CE38186 WormBase description: G1/S-specfic cyclin C like
F43D9.4 F43D9.4 P W All gene names: sec-1; sip-1; F43D9.4; F43D9.4.1; F43D9.4.2; 3L596; CE00994; NM_066915; SIP/1; SIP1_CAEEL; WBGene00004798; WP:CE00994 WormBase description: Heat shock hsp20 proteins
F43E2.2 F43E2.2 P W All gene names: F43E2.2; 2H665; CE28327; WBGene00018391; WP:CE28327
F43E2.7 F43E2.7 P W All gene names: F43E2.7; 2H664; CE32664; CE33087; WBGene00018395; WP:CE32664; WP:CE33087
F44E2.7 F44E2.7 P W All gene names: F44E2.7; F44E2.7b.1; F44E2.7b.2; F44E2.7b.3; F44E2.7b.4; F44E2.7b.5; 3J936; CE24975; CE29802; CE30994; CE30995; WBGene00018420; WP:CE24975; WP:CE29802; WP:CE30994; WP:CE30995; YL57_CAEEL
F44E7.9 F44E7.9 P W All gene names: F44E7.9; 5G271; CE10396; O16254_CAEEL; WBGene00018431; WP:CE10396
F45E12.5 F45E12.5 P W All gene names: F45E12.5; F45E12.5b.1; F45E12.5b.2; 2H598; CE02741; CE32049; WBGene00018475; WP:CE02741; WP:CE32049
F45H11.2 F45H11.2 P W All gene names: ned-8; F45H11.2; 1K950; CE10552; NEDD8_CAEEL; NM_060316; WBGene00003587; WP:CE10552 WormBase description: The ned-8 gene encodes a ubiquitin-like protein that is required for both embryogenesis and terminal hypodermal differentiation. WormBase CDS description: ubiquitin
F48A11.6 F48A11.6 P W All gene names: F48A11.6; WBGene00043343
F48C1.5 F48C1.5 P W All gene names: F48C1.5; 1F884; CE10740; WBGene00018598; WP:CE10740
F48C1.6 F48C1.6 P W All gene names: F48C1.6; 1F886; CE10742; WBGene00018599; WP:CE10742
F52B11.7 F52B11.7 P W All gene names: F52B11.7; 4O872; CE18727; WBGene00009928; WP:CE18727
F52B5.6 F52B5.6 P W All gene names: rpl-25.2; F52B5.6; F52B5.6.1; F52B5.6.2; 1I906; CE05721; NM_059862; R23A2_CAEEL; WBGene00004439; WP:CE05721 WormBase description: rpl-25.2 encodes a large ribosomal subunit L23a protein. WormBase CDS description: 60S ribosomal protein
F53A2.5 F53A2.5 P W All gene names: dro-1; F53A2.5; 3O431; CE16097; NM_067349; WBGene00001092; WP:CE16097 WormBase description: Archael histone like
F53A2.6 F53A2.6 P W All gene names: ife-1; F53A2.6; F53A2.6.1; F53A2.6.2; F53A2.6.3; 3O433; CE31809; IF4E1_CAEEL; NM_067350; WBGene00002059; WP:CE31809 WormBase description: The ife-1 gene encodes one of five C. elegans homologs of the mRNA cap-binding protein eIF4E; it is specifically required for spermatogenesis, and is expressed in P granules. WormBase CDS description: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E (EIF-4E) (EIF4E) (MRNA CAP-BINDING PROTEIN) (EIF-4F 25 KD SUBUNIT)
F53B7.3 F53B7.3 P W All gene names: F53B7.3; 5L480; CE05922; WBGene00009966; WP:CE05922
F53E10.6 F53E10.6 P W All gene names: F53E10.6; F53E10.6.1; F53E10.6.2; 5D80; CE10930; RRP15_CAEEL; WBGene00018762; WP:CE10930
F53G12.8 F53G12.8 P W All gene names: F53G12.8; 1A587; CE36697; WBGene00018773; WP:CE36697
F54C4.1 F54C4.1 P W All gene names: F54C4.1; 3A705; CE19890; WBGene00018793; WP:CE19890
F54C4.2 F54C4.2 P W All gene names: spt-4; F54C4.2; 3A686; CE19891; NM_064734; SPT4H_CAEEL; WBGene00005014; WP:CE19891
F54C9.9 F54C9.9 P W All gene names: F54C9.9; 2I871; CE20865; WBGene00010044; WP:CE20865
F54D5.2 F54D5.2 P W All gene names: F54D5.2; 2L865; CE36491; WBGene00010048; WP:CE36491
F54D5.8 F54D5.8 P W All gene names: dnj-13; F54D5.8; 2L839; CE03412; NM_064067; WBGene00001031; WP:CE03412 WormBase description: This gene encodes a protein containing a DnaJ ('J') domain. WormBase CDS description: DNAJ protein
F54E7.2 F54E7.2 P W All gene names: rps-12; F54E7.2; F54E7.2.1; F54E7.2.2; 3G769; CE26896; NM_065820; RS12_CAEEL; WBGene00004481; WP:CE26896 WormBase description: rps-12 encodes a small ribosomal subunit S12 protein; by homology, RPS-12 is predicted to function in protein biosynthesis; in C. elegans, RPS-12 activity is required for embryonic and germline development, normal movement, and the overall health of the animal.
F54F2.7 F54F2.7 P W All gene names: F54F2.7; 3J896; CE29395; WBGene00018835; WP:CE29395; YMA7_CAEEL
F55A11.1 F55A11.1 P W All gene names: F55A11.1; 5M244; CE05943; WBGene00010075; WP:CE05943 WormBase description: EF hand domains
F55D12.5 F55D12.5 P W All gene names: F55D12.5; CE36387; WBGene00010113; WP:CE36387 WormBase description: Activin types I and II receptor domain
F55G1.6 F55G1.6 P W All gene names: F55G1.6; 4I237; CE34886; WBGene00018902; WP:CE34886
F56C9.1 F56C9.1 P W All gene names: CEGLC-7B; Ce-glc-7beta; gsp-2; F56C9.1; F56C9.1.1; F56C9.1.2; 3I433; CE01319; GLC7B_CAEEL; WBGene00001748; WP:CE01319
F56D5.4 F56D5.4 P W All gene names: F56D5.4; 4K164; WBGene00014772
F57B10.10 F57B10.10 P W All gene names: dad-1; F57B10.10; F57B10.10.1; F57B10.10.2; 1H132; CE11316; DAD1_CAEEL; NM_059488; WBGene00000896; WP:CE11316 WormBase description: dad-1 encodes an ortholog of human DAD1 (OMIM:600243) that inhibits cell death and can functionally complement the hamster protein in cultured cells.
F57B9.6 F57B9.6 P W All gene names: inf-1; F57B9.6; F57B9.6a.1; F57B9.6a.2; 3I21; CE01341; CE38524; Ce1F; CeIF; IF4A_CAEEL; NM_066108; WBGene00002083; WP:CE01341; WP:CE38524 WormBase description: inf-1 encodes a protein with high similarity to eukaryotic initiation factor 4A.
F58A4.10 F58A4.10 P W All gene names: ubc-7; F58A4.10; F58A4.10.1; F58A4.10.2; 3K720; CE00216; NM_066732; UBC7_CAEEL; WBGene00006704; WP:CE00216 WormBase description: Ubiquitin conjugating enzyme
F58A4.9 F58A4.9 P W All gene names: F58A4.9; 3K718; AC19; CE00225; RPO1D_CAEEL; WBGene00010230; WP:CE00225 WormBase description: RNA Pol I/III 16Kd polypeptide
F58B3.4 F58B3.4 P W All gene names: F58B3.4; 4M394; CE36170; WBGene00010231; WP:CE36170
F58E10.3 F58E10.3 P W All gene names: F58E10.3; F58E10.3.1; F58E10.3.2; F58E10.3.3; F58E10.3.4; F58E10.3.5; F58E10.3.6; 5O490; CE18785; WBGene00010260; WP:CE18785 WormBase description: ATP-dependent helicase (DEAD box)
F58E10.4 F58E10.4 P W All gene names: aip-1; F58E10.4; 5O493; CE18786; NM_074078; WBGene00000097; WP:CE18786 WormBase description: aip-1 encodes an AN-1-like zinc finger-containing protein homologous to arsenite-inducible RNA-associated protein (AIRAP), conserved among C. elegans, Drosophila, and mammals; like AIRAP itself, AIP-1 protects cells from arsenite toxicity; AIP-1 is a predicted RNA binding protein that may function in ubiquitin-mediated proteolysis following aresenite treatment; AIP-1 does not appear to be essential for viability, but is expressed at high levels in hypodermal and intestinal cells following such treatment.
F59A2.3 F59A2.3 P W All gene names: F59A2.3; F59A2.3.1; F59A2.3.2; 3E487; CE17940; WBGene00010303; WP:CE17940; YMI3_CAEEL WormBase description: Splicing factor-associated 32K chain
F59A2.5 F59A2.5 P W All gene names: F59A2.5; 3E495; CE01023; WBGene00010305; WP:CE01023
F59A3.3 F59A3.3 P W All gene names: F59A3.3; 1G74; CE11420; RM24_CAEEL; WBGene00019076; WP:CE11420
F59A6.6 F59A6.6 P W All gene names: rnh-1; F59A6.6; F59A6.6b.1; F59A6.6b.2; 2F287; CE33406; CE33659; NM_062519; NM_182182; WBGene00004382; WP:CE33406; WP:CE33659 WormBase description: rnh-1 encodes a putative RNAse H that is predicted, by phylogenetic profiling, to be mitochondrial.
F59C6.4 F59C6.4 P W All gene names: F59C6.4; 1L95; CE11462; WBGene00010325; WP:CE11462
F59E12.4 F59E12.7 P W
H04D03.3 H04D03.3 P W All gene names: H04D03.3; 3L533; CE16167; WBGene00010364; WP:CE16167
H06H21.6 H06H21.6 P W All gene names: ubxn-6; H06H21.6; H06H21.6.1; H06H21.6.2; H06H21.6.3; H06H21.6.4; H06H21.6.5; 4F572; CE33662; WBGene00019163; WP:CE33662
H20J04.5 H20J04.D P W
H38K22.2 H38K22.2 P W All gene names: dcn-1; H38K22.2; 3F405; CE33527; CE33528; DCN1_CAEEL; NM_065465; NM_065466; WBGene00010428; WP:CE33527; WP:CE33528
JC8.3 JC8.3 P W All gene names: rpl-12; JC8.3; JC8.3c.1; JC8.3c.2; JC8.3c.3; JC8.3c.4; JC8.3c.5; JC8.3c.6; JC8.3c.7; JC8.3c.8; 4O4; CE17986; CE39743; NM_070141; NM_070142; RL12_CAEEL; WBGene00004424; WP:CE17986; WP:CE39743 WormBase description: rpl-12 encodes a large ribosomal subunit L12 protein required in mass RNAi assays for embryonic viability, fertility, normally rapid growth, and general health; the rpl-12 transcription unit has a nonsense transcript that is up-regulated in vivo by smg[-] mutations, indicating that rpl-12 is a natural substrate for SMG-mediated nonsense suppresssion; several other natural mRNA substrates of SMG suppression (e.g., rpl-3, rpl-7, rpl-10) have protein products that are involved in translation.
K01H12.2 K01H12.2 P W All gene names: K01H12.2; 4K472; CE03454; WBGene00010485; WP:CE03454 WormBase description: ADP/ATP carrier protein
K03B4.1 K03B4.1 P W All gene names: K03B4.1; 5F169; CE28579; WBGene00019353; WP:CE28579
K03H1.7 K03H1.7 P W All gene names: K03H1.7; 3L37; CE00573; WBGene00010542; WP:CE00573
K04C2.3 K04C2.3 P W All gene names: K04C2.3; K04C2.3a.1; K04C2.3a.2; 3H963; CE00721; CE32689; WBGene00019381; WP:CE00721; WP:CE32689
K04G2.4 K04G2.4 P W All gene names: K04G2.4; 1I615; CE06098; WBGene00010563; WP:CE06098
K05C4.7 K05C4.7 P W All gene names: K05C4.7; 1P331; CE19975; WBGene00010583; WP:CE19975
K06A5.6 K06A5.6 P W All gene names: K06A5.6; K06A5.6.1; K06A5.6.2; 1H40; CE11776; WBGene00019433; WP:CE11776 WormBase description: acyl-coA dehydgrogenase
K07A1.10 K07A1.10 P W All gene names: K07A1.10; 1K190; CE39387; WBGene00010616; WP:CE39387
K07A12.3 K07A12.3 P W All gene names: asg-1; K07A12.3; K07A12.3.1; K07A12.3.2; 1J269; ATPL1_CAEEL; CE11868; NM_059951; WBGene00000209; WP:CE11868 WormBase description: asg-1 encodes a homolog of the proton-translocating F0 ATP synthase complex subunit g; by homology, ASG-1 is predicted to function in ATP synthesis, although its precise role in ATP anabolism is not yet known; in C. elegans, asg-1 activity is required for transposon silencing in the germline, suggesting that healthy energy metabolism is necessary for this process; in addition, large-scale RNAi screens indicate that asg-1 activity is required for embryonic and germline development, normal post-embryonic growth rates, and normal body morphology. WormBase CDS description: ATP synthase subunit g
K07D4.3 K07D4.3 P W All gene names: rpn-11; K07D4.3; K07D4.3.1; K07D4.3.2; 2E332; CE19527; NM_062311; PSDE_CAEEL; WBGene00004467; WP:CE19527 WormBase description: rpn-11 encodes a predicted non-ATPase subunit of the 19S regulatory complex of the proteasome that affects adult viability, osmoregulation, embryonic viability, and movement; interacts with itself, RPN-9, and F55A11.3, based on yeast two-hybrid assays.
K07H8.3 K07H8.3 P W All gene names: K07H8.3; 4J55; CE18023; WBGene00019505; WP:CE18023
K08D10.3 K08D10.3 P W All gene names: rnp-3; K08D10.3; 4E939; CE07355; NM_068104; WBGene00004386; WP:CE07355 WormBase description: U1 small nuclear ribonucleoprotein A
K08E3.5 K08E3.5 P W All gene names: K08E3.5; K08E3.5a.1; K08E3.5a.2; K08E3.5a.3; K08E3.5f.1; K08E3.5f.2; 3O854; CE18869; CE18870; CE18871; CE29431; CE33804; CE37125; Q9XUS5_CAEEL; WBGene00010665; WP:CE18869; WP:CE18870; WP:CE18871; WP:CE29431; WP:CE33804; WP:CE37125 WormBase description: UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (EC 2.7.7.9) (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP)
K08E4.6 K08E4.6 P W All gene names: K08E4.6; 4M842; CE06146; WBGene00010670; WP:CE06146 WormBase description: emp24/gp25L/p24 family
K08F11.4 K08F11.4 P W All gene names: yrs-1; K08F11.4; 4F476; CE29515; CE31714; NM_171324; NM_171325; WBGene00006968; WP:CE29515; WP:CE31714 WormBase description: yrs-1 encodes a tyrosinyl tRNA synthetase predicted to be mitochondrial.
K08F4.1 K08F4.1 P W All gene names: K08F4.1; K08F4.1.1; K08F4.1.2; 4K888; CE06149; WBGene00010676; WP:CE06149 WormBase description: Yeast Chl2p like
K12C11.2 K12C11.2 P W All gene names: smo-1; K12C11.2; 1B815; CE18056; NM_058441; SMT3; SUMO_CAEEL; WBGene00004888; WP:CE18056
M01B12.3 M01B12.3 P W All gene names: arx-7; M01B12.3; 1D638; CE18061; NM_058698; WBGene00000205; WP:CE18061 WormBase description: arx-7 encodes the C. elegans ortholog of the p16Arc subunit of the actin-related protein (Arp)2/3 complex.
M01D7.6 M01D7.6 P W All gene names: emr-1; M01D7.6; M01D7.6.1; M01D7.6.2; M01D7.6.3; 1C315; CE12270; EMR1_CAEEL; NM_058506; WBGene00001309; WP:CE12270 WormBase description: emr-1 gene encodes a homolog of the human integral nuclear membrane protein emerin (EMD, OMIM:300384, mutated in X-linked Emery-Dreifuss muscular dystrophy); EMR-1 belongs to a family of proteins sharing the LEM-domain that are generally conserved in metazoa; EMR-1 protein is found in the nuclear envelopes of all cell types except sperm, in embryos, larvae, and adults; EMR-1 binds the lamin LMN-1, and functionally overlaps with LEM-2 with respect to chromosome segregation and cell division.
M02F4.3 M02F4.2 P W
M03C11.6 M03C11.6 P W All gene names: M03C11.6; 3L510; CE37782; WBGene00010843; WP:CE37782
M04B2.3 M04B2.3 P W All gene names: gfl-1; M04B2.3; 4M287; CE12388; NM_069771; WBGene00001585; WP:CE12388 WormBase description: gfl-1 encodes an ortholog of human GLIOMA-AMPLIFIED SEQUENCE-41 (GAS41; OMIM:602116, found in increased copy number in low-grade glioma); loss of GLF-1, which is predicted to associate with chromatin, results in potent suppression of the RNA interference (RNAi) mechanism; GLF-1 is also similar to the transcription factors (yeast and human) AF-9 and human ENL, and thus may represent a novel class of transcription factors. WormBase CDS description: Human AF-9 protein like
M117.2 M117.2 P W All gene names: ftt-1; par-5; M117.2; M117.2.1; M117.2.2; M117.2.3; 14331_CAEEL; 4M586; CE06200; NM_069834; WBGene00003920; WP:CE06200 WormBase description: PAR-5 is a 14-3-3 protein. WormBase CDS description: 14-3-3 protein
M18.7 M18.7 P W All gene names: aly-3; M18.7; M18.7.1; M18.7.2; 4M889; CE06198; NM_069900; Q21559_CAEEL; WBGene00000122; WP:CE06198 WormBase description: RNA recognition motif. (aka RRM, RBD, or RNP domain)
M28.5 M28.5 P W All gene names: phi-9; M28.5; M28.5.1; M28.5.2; 2K948; CE02283; NH2L1_CAEEL; SNU13CE; WBGene00010896; WP:CE02283 WormBase description: ribosomal protein (L7AE family)
M7.1 M7.1 P W All gene names: let-70; ubc-2; M7.1; 4L846; CE03482; NM_069664; UBC2_CAEEL; WBGene00002344; WP:CE03482 WormBase description: let-70 encodes a class I E2 ubiquitin conjugating enzyme; let-70 was identified in screens for essential genes and phenotypic analyses indicate that loss of let-70 activity results in embryonic and larval lethality with defects in sarcomere assembly; purified LET-70 can stimulate the self-ubiquitylation activities of CHN-1 and UFD-2, E4 ubiquitin conjugation factors and, in addition, can stimulate the CHN-1- and UFD-2-dependent multiubiquitylation of UNC-45, a myosin-directed chaperone; in this manner, LET-70 may regulate UNC-45 degradation and myosin assembly; RNA blot analyses and a let-70-lacZ reporter fusion reveal that let-70 is abundantly expressed at all stages of development, including the dauer larval stage; strong staining is observed in most somatic tissues until adult stages, when expression generally becomes restricted to the nervous system. WormBase CDS description: ubiquitin-conjugating enzyme E2-17 KD
R01H2.6 R01H2.6 P W All gene names: ubc-18; R01H2.6; 3I158; CE25067; NM_066140; WBGene00006713; WP:CE25067 WormBase description: ubc-18 encodes an E2 ubiquitin-conjugating enzyme related to human UBCH7 (OMIM:603731); UBC-18 activity is required for normal growth and reproduction, and UBC-18 functions redundantly with LIN-35/Rb and other class B synthetic multivulval (SynMuv) gene products to regulate pharyngeal morphogenesis during embryonic development; ubc-18 transcripts are detected in the germline, embryos, late larval stages, and adults, suggesting that UBC-18 may function maternally to regulate several aspects of C. elegans development; the substrates of UBC-18 are not yet known.
R02D3.2 R02D3.2 P W All gene names: cogc-8; R02D3.2; 4A995; CE18096; COG8_CAEEL; WBGene00019820; WP:CE18096 WormBase description: cogc-8 encodes an ortholog of mammalian COG-8, a subunit of lobe B of the conserved oligomeric Golgi complex (COGC); COGC-8 is weakly required for normal gonadal distal tip cell migration, a process that also requires seven other orthologs of COGC subunits; like other lobe B subunits in both C. elegans and S. cerevisiae, COGC-8 is only partially required for normal function, while lobe A subunits are strongly required in either worms or yeast.
R02D5.7 R02D5.7 P W All gene names: R02D5.7; 5O960; CE29435; WBGene00010980; WP:CE29435
R05D11.3 R05D11.3 P W All gene names: CE-NTF2; ran-4; R05D11.3; R05D11.3.1; R05D11.3.2; 1J167; CE06238; NM_059921; NTF2_CAEEL; WBGene00004305; WP:CE06238 WormBase description: ran-4 encodes a ortholog of NUCLEAR TRANSPORT FACTOR 2 (NTF2) from S. cerevisiae and metazoa, which is predicted to interact with nucleoporins and to promote transport of RAN-1(+GDP) into the nucleus; RAN-4/NTF2 proteins are paralogous to the N-terminal domain of RasGAP SH3 binding proteins such as Drosophila RASPUTIN, and to delta-5-3-ketosteroid isomerases, while having no homology to Ran proteins per se; RAN-4 is essential for early embryogenesis; in mass RNAi assays, ran-4 is needed for embryonic viability, normally rapid growth, fertility, and normal pronuclear envelopes in the embryo. WormBase CDS description: nuclear transport factor 2 like
R05D11.4 R05D11.4 P W All gene names: R05D11.4; R05D11.4.1; R05D11.4.2; 1J177; CE06239; WBGene00011032; WP:CE06239 WormBase description: ATP dependent RNA helicase
R05D11.7 R05D11.7 P W All gene names: R05D11.7; 1J179; CE06242; WBGene00011035; WP:CE06242
R05F9.10 R05F9.10 P W All gene names: sgt-1; R05F9.10; 2F192; CE04813; Q21746_CAEEL; WBGene00019893; WP:CE04813 WormBase description: TPR domain repeats
R05H5.5 R05H5.5 P W All gene names: R05H5.5; 2K490; CE02292; WBGene00011040; WP:CE02292
R07E5.1 R07E5.1 P W All gene names: R07E5.1; 3F501; CE00658; WBGene00011109; WP:CE00658
R07E5.10 R07E5.10 P W All gene names: pdcd-2; R07E5.10; 3F508; CE18125; WBGene00011116; WP:CE18125 WormBase description: This gene encodes a homolog of mammalian PROGRAMMED CELL DEATH 2 (PDCD2). WormBase CDS description: Apoptosis protein RP-8
R07E5.6 R07E5.6 P W All gene names: R07E5.6; 3F489; CE18124; WBGene00011114; WP:CE18124 WormBase description: Coiled-coil protein
R07G3.5 R07G3.5 P W All gene names: R07G3.5; 2H888; CE31979; WBGene00019941; WP:CE31979; YRO5_CAEEL
R07H5.3 R07H5.3 P W All gene names: R07H5.3; 4L951; CE12554; CE35186; WBGene00011123; WP:CE12554; WP:CE35186
R08C7.3 R08C7.3 P W All gene names: htz-1; R08C7.3; R08C7.3.1; R08C7.3.2; R08C7.3.3; 4F211; CE07426; H2AV_CAEEL; WBGene00019947; WP:CE07426 WormBase description: histone H2A variant
R08D7.8 R08D7.4 P W
R09B3.2 R09B3.2 P W All gene names: R09B3.2; 1M500; CE16307; WBGene00011155; WP:CE16307 WormBase description: RNA recognition motif. (aka RRM, RBD, or RNP domain)
R09B3.3 R09B3.3 P W All gene names: R09B3.3; R09B3.3.1; R09B3.3.2; 1M502; CE16308; WBGene00011156; WP:CE16308 WormBase description: RNA recognition motif. (aka RRM, RBD, or RNP domain)
R09E12.3 R09E12.3 P W All gene names: R09E12.3; 5B253; CE12646; WBGene00019983; WP:CE12646
R10A10.2 R10A10.2 P W All gene names: rbx-2; R10A10.2; 1G996; CE12670; NM_059448; WBGene00019993; WP:CE12670 WormBase description: The R10A10.2 gene encodes an ortholog of the mammalian zinc RING finger protein SAG, which protects cells from apoptosis induced by redox agents and is a component of ubiquitin-ligase (E3) complexes; mammalian SAG binds to the yeast Cul1 protein, complements the lethality of a mutation in yeast Sag, and (when bound to yeast Cul1) has ubiquitin ligase activity and promotes poly-ubiquitination of E2/Cdc34. WormBase CDS description: zinc finger protein
R10D12.12 R10D12.12 P W All gene names: R10D12.12; 5O442; CE23919; WBGene00011193; WP:CE23919
R10D12.14 R10D12.14 P W All gene names: R10D12.14; CE12698; WBGene00011195; WP:CE12698
R10H10.1 R10H10.1 P W All gene names: lpd-8; R10H10.1; R10H10.1.1; R10H10.1.2; 4L153; CE06292; NM_069516; WBGene00003064; WP:CE06292 WormBase description: lpd-8 encodes a homolog of human and mouse HIRA-interacting protein-5; LPD-8 has C-terminal similarity to a domain of NifU observed in thioredoxin-like proteins and domains (COG0694), and is predicted to be mitochondrial on phylogenetic grounds. WormBase CDS description: Yeast hypothetical protein YKE0 like
R119.3 R119.3 P W All gene names: R119.3; 1A848; CE28758; WBGene00020089; WP:CE28758 WormBase description: dehydrogenase
R119.6 R119.6 P W All gene names: taf-4; R119.6; 1A861; CE39613; NM_058327; WBGene00006385; WP:CE39613 WormBase description: taf-4 encodes a TAFII (TBP(TATA-binding protein)-associated factor) that is orthologous to human TAF4 (hTAFII130); TAF-4 is predicted to be a component of the TFIID mRNA transcription complex and is generally required for early embryonic mRNA transcription; consistent with this observation, taf-4(RNAi) results in embryonic lethality at the ~100-cell stage with little cell differentiation, similar to the loss of AMA-1/RNA polymerase II activity; TAF-4 is detected in nuclei in the adult germline, oocytes, and embryo, from the 2-cell stage through early morphogenesis.
R11A5.2 R11A5.2 P W All gene names: R11A5.2; 1I434; CE12724; WBGene00011230; WP:CE12724
R11A8.5 R11A8.5 P W All gene names: R11A8.5; 4L132; CE06303; WBGene00011239; WP:CE06303 WormBase description: glutathione S-transferase
R11D1.8 R11D1.8 P W All gene names: rpl-28; R11D1.8; R11D1.8.1; R11D1.8.2; R11D1.8.3; R11D1.8.4; R11D1.8.5; 5N208; CE06313; NM_073779; RL28_CAEEL; WBGene00004442; WP:CE06313 WormBase description: rpl-28 encodes a large ribosomal subunit L28 protein. WormBase CDS description: ribsomal protein L28 like
R11D1.9 R11D1.9 P W All gene names: R11D1.9; 5N209; CE06314; RM49_CAEEL; WBGene00011247; WP:CE06314 WormBase description: Human NOF1 protein like
R12C12.5 R12C12.5 P W All gene names: R12C12.5; 2G334; CE29820; WBGene00020025; WP:CE29820
R12C12.6 R12C12.6 P W All gene names: R12C12.6; 2G336; CE02851; CE39619; WBGene00020026; WP:CE02851; WP:CE39619
R12E2.12 R12E2.12 P W All gene names: R12E2.12; 1E742; CE33159; WBGene00020037; WP:CE33159
R12E2.3 R12E2.3 P W All gene names: rpn-8; R12E2.3; R12E2.3.1; R12E2.3.2; 1E745; CE18135; NM_058918; WBGene00004464; WP:CE18135
R13A5.12 R13A5.12 P W All gene names: lpd-7; R13A5.12; R13A5.12.1; R13A5.12.2; 3I663; CE21123; NM_066260; WBGene00003063; WP:CE21123 WormBase description: lpd-7 encodes a BRCT domain-containing protein that is orthologous to Saccharomyces cerevisiae Nop7p and the vertebrate pescadillo proteins required for nucleolar assembly, ribosome biogenesis, and cell proliferation; loss of lpd-7 activity via RNAi indicates that, in C. elegans, LPD-7 is required for fat storage and for larval growth and development; based upon its similarity to the yeast and vertebrate proteins, LPD-7 is predicted to localize to the nucleolus.
R13A5.8 R13A5.8 P W All gene names: rpl-9; R13A5.8; R13A5.8.1; R13A5.8.2; 3I662; CE01380; NM_066259; RL9_CAEEL; WBGene00004420; WP:CE01380 WormBase description: rpl-9 encodes a large ribosomal subunit L9 protein that affects fertility and embryonic viability. WormBase CDS description: Ribosomal protein L9
R144.4 R144.4, R144.8 P W All gene names: R144.4; 3G109; CE34587; CE34588; WBGene00020094; WP:CE34587; WP:CE34588
R144.4 R144.4, R144.8 P W All gene names: R144.4; 3G109; CE34587; CE34588; WBGene00020094; WP:CE34587; WP:CE34588
R148.3 R148.3 P W All gene names: R148.3; 3E271; CE28640; CE32710; Q8ITY8_CAEEL; WBGene00020102; WP:CE28640; WP:CE32710
R151.6 R151.6 P W All gene names: R151.6; R151.6.1; R151.6.2; 3I312; CE39620; DERL2_CAEEL; WBGene00020109; WP:CE39620
R151.9 R151.9 P W All gene names: R151.9; 3H288; 3I288; CE00827; PFD5_CAEEL; WBGene00020112; WP:CE00827
R186.3 R186.3 P W All gene names: R186.3; 5N446; CE12874; WBGene00011306; WP:CE12874 WormBase description: signal recognition particle receptor beta subunit like
R53.6 R53.6 P W All gene names: R53.6; 2K261; CE35902; PSF1_CAEEL; WBGene00011275; WP:CE35902
R74.4 R74.4 P W All gene names: dnj-16; R74.4; 3F281; CE01057; NM_065438; WBGene00001034; WP:CE01057 WormBase description: This gene encodes a protein containing a DnaJ ('J') domain. WormBase CDS description: DNAJ domain
T01B11.4 T01B11.4 P W All gene names: tag-316; T01B11.4; 4J224; CE12898; WBGene00020140; WP:CE12898 WormBase description: ADP/ATP translocase
T01B7.3 T01B7.3 P W All gene names: rab-21; T01B7.3; 2J2; CE03587; NM_063453; WBGene00004279; WP:CE03587 WormBase description: ras-related protein
T01B7.4 T01B7.4 P W All gene names: cyn-11; cyp-11; T01B7.4; 2J6; CE03588; CYP11_CAEEL; NM_063454; WBGene00000887; WP:CE03588 WormBase description: cyp-11 encodes a divergent cyclophilin D isoform, with alterations in the normally well-conserved cyclophilin-binding domain, and a central 7-8 residue insert not usually found in cyclophilins, except from plants; CYP-11 has sluggish but detectable peptidyl-prolyl isomerase activity in vitro, suggesting that it has a specialized substrate in vivo; CYP-11 is dispensable for viability and gross morphology in mass RNAi screens. WormBase CDS description: peptidyl-prolyl cis-trans isomerase
T01B7.5 T01B7.5 P W All gene names: T01B7.5; 2J11; CE23934; CE38216; WBGene00011311; WP:CE23934; WP:CE38216
T01C3.7 T01C3.7 P W All gene names: fib-1; T01C3.7; T01C3.7.1; T01C3.7.2; T01C3.7.3; T01C3.7.4; 5P482; CE12920; FBRL_CAEEL; NM_074290; WBGene00001423; WP:CE12920 WormBase description: fibrillarin
T03D8.2 T03D8.2 P W All gene names: T03D8.2; 5V309; CE18920; WBGene00011391; WP:CE18920 WormBase description: Ribosomal protein S12
T03F1.8 T03F1.8 P W All gene names: T03F1.8; 1E428; CE29460; WBGene00020190; WP:CE29460 WormBase description: guanylate kinase
T04A8.9 T04A8.9 P W All gene names: dnj-18; T04A8.9; T04A8.9.1; T04A8.9.2; 3F787; CE01078; NM_065561; WBGene00001036; WP:CE01078 WormBase description: This gene encodes a protein containing a DnaJ ('J') domain. WormBase CDS description: DNAJ
T05C12.7 T05C12.7 P W All gene names: cct-1; tcp-1; T05C12.7; T05C12.7.1; T05C12.7.2; 2I477; CE02319; NM_063321; TCPA_CAEEL; WBGene00000377; WP:CE02319 WormBase description: eukaryotic cytosolic chaperonin; affects viability and fertility, and is expressed in various muscle and neuronal cells: near the pharynx, near the anal sphincter, in the ventral nerve cord and the nerve ring; occasionally the expression is visible in hypodermal cells and in some vulval cells. WormBase CDS description: T-complex protein
T05F1.3 T05F1.3 P W All gene names: rps-19; T05F1.3; T05F1.3.1; T05F1.3.2; 1K202; CE13265; NM_060154; RS19_CAEEL; WBGene00004488; WP:CE13265; rpS19 WormBase description: rps-19 encodes a small ribosomal subunit S19 protein, orthologous to human RPS19 (OMIM:603474, mutated in Diamond-Blackfan anemia). WormBase CDS description: Ribosomal protein S19e
T05G5.7 T05G5.7 P W All gene names: T05G5.7; 3K849; CE00319; WBGene00011501; WP:CE00319; YNP7_CAEEL
T05H10.6 T05H10.6 P W All gene names: T05H10.6; T05H10.6a.1; T05H10.6a.2; T05H10.6a.3; T05H10.6a.4; T05H10.6b.1; T05H10.6b.2; CE01643; CE32929; NM_063292; NM_182153; ODPA_CAEEL; WBGene00011510; WP:CE01643; WP:CE32929 WormBase description: T05H10.6 encodes an ortholog of the human gene PYRUVATE DEHYDROGENASE (LIPOAMIDE) ALPHA 1 (PDHA1; OMIM:312170), which when mutated leads to Leigh syndrome (OMIM:256000); the T05H10.6 protein is predicted to be mitochondrial with 68% accuracy.
T06D8.7 T06D8.7 P W All gene names: T06D8.7; T06D8.7.1; T06D8.7.2; 2L526; CE02328; WBGene00011528; WP:CE02328
T06G6.9 T06G6.9 P W All gene names: vbp-1; T06G6.9; 1N321; CE13349; NM_060827; PFD3_CAEEL; WBGene00006889; WP:CE13349 WormBase description: Human VHL binding protein like
T07A9.11 T07A9.11 P W All gene names: rps-24; T07A9.11; T07A9.11.1; T07A9.11.2; 4B139; CE29465; NM_067514; WBGene00004493; WP:CE29465 WormBase description: rps-24 encodes a small ribosomal subunit S24 protein; by homology, RPS-24 is predicted to function in protein biosynthesis; in C. elegans, RPS-24 activity is required for germline development and the overall health of the animal. WormBase CDS description: ribosomal protein
T07A9.2 T07A9.2 P W All gene names: ers-3; qrs-6; T07A9.2; 4B142; CE34997; NM_067516; WBGene00001338; WP:CE34997 WormBase description: ers-3 encodes a a glutamine (E)/glutaminyl (Q) tRNA synthetase. WormBase CDS description: tRNA synthetase
T07E3.3 T07E3.3 P W All gene names: T07E3.3; 3H993; CE01384; WBGene00020314; WP:CE01384
F57B9.7 T07E3.7 P W
T07F8.4 T07F8.4 P W All gene names: T07F8.4; 2H420; CE13385; WBGene00020320; WP:CE13385
T08B2.10 T08B2.10 P W All gene names: rps-17; T08B2.10; T08B2.10.1; T08B2.10.2; 1G796; CE26948; NM_059394; RS17_CAEEL; WBGene00004486; WP:CE26948 WormBase description: rps-17 encodes a small ribosomal subunit S17 protein. WormBase CDS description: 40S ribosomal protein S17
T09A5.5 T09A5.5 P W All gene names: T09A5.5; T09A5.5.1; T09A5.5.2; 2I142; CE01086; WBGene00011634; WP:CE01086; YNZ5_CAEEL
T10B5.5 T10B5.5 P W All gene names: T10B5.5; T10B5.5b.1; T10B5.5b.2; 5C353; CE28255; CE33316; WBGene00020391; WP:CE28255; WP:CE33316
T10C6.5 T10C6.5 P W All gene names: T10C6.5; 5Q503; CE16380; O45766_CAEEL; WBGene00011687; WP:CE16380
T12A2.7 T12A2.7 P W All gene names: T12A2.7; 3H334; CE30396; WBGene00020441; WP:CE30396
T12D8.2 T12D8.2 P W All gene names: drr-2; T12D8.2; T12D8.2.1; T12D8.2.2; 3O734; CE16399; WBGene00011730; WP:CE16399 WormBase description: RNA recognition motif. (aka RRM, RBD, or RNP domain)
T12D8.6 T12D8.6 P W All gene names: T12D8.6; 3O713; CE16403; WBGene00011734; WP:CE16403 WormBase description: EF hand
T12F5.1 T12F5.1 P W All gene names: T12F5.1; 1E311; CE13595; WBGene00020466; WP:CE13595
T12G3.5 T12G3.5 P W All gene names: T12G3.5; T12G3.5.1; T12G3.5.2; 4M795; CE06441; RM51_CAEEL; WBGene00011740; WP:CE06441
T13F2.2 T13F2.2 P W All gene names: T13F2.2; T13F2.2.1; T13F2.2.2; 4K562; CE13621; TCP4_CAEEL; WBGene00011743; WP:CE13621 WormBase description: single-stranded DNA binding protein P9
T13H5.5 T13H5.5 P W All gene names: T13H5.5; 2I817; CE03656; WBGene00011759; WP:CE03656
T14G10.3 T14G10.3 P W All gene names: T14G10.3; 4K923; CE35618; WBGene00011773; WP:CE35618 WormBase description: Transthyretin-like family
T15H9.2 T15H9.2 P W All gene names: T15H9.2; 2J904; CE01665; WBGene00011788; WP:CE01665; YRY2_CAEEL WormBase description: coiled-coil
T16G1.10 T16G1.10 P W All gene names: pqn-68; T16G1.10; 5N431; CE20080; NM_073839; WBGene00004151; WP:CE20080 WormBase description: The protein product of this gene was predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS72 release of WormBase, i.e., in wormpep77).
T16G1.11 T16G1.11 P W All gene names: eif-3.K; pqn-69; T16G1.11; 5N435; CE20081; NM_073840; WBGene00001233; WP:CE20081 WormBase description: The protein product of this gene was predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS72 release of WormBase, i.e., in wormpep77).
T19A6.2 T19A6.2 P W All gene names: ngp-1; T19A6.2; T19A6.2b.1; T19A6.2b.2; T19A6.2b.3; T19A6.2b.4; T19A6.2c.1; T19A6.2c.2; 1I973; CE32493; CE32494; CE38417; NM_059874; NM_059875; WBGene00003596; WP:CE32493; WP:CE32494; WP:CE38417 WormBase description: AUTOANTIGEN NGP-1
T19B10.4 T19B10.4 P W All gene names: pqn-70; T19B10.4; 5L708; CE16414; CE16415; NM_073449; NM_073450; WBGene00004152; WP:CE16414; WP:CE16415 WormBase description: The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
T19H12.2 T19H12.2 P W All gene names: T19H12.2; T19H12.2.1; T19H12.2.2; 5F369; AN322_CAEEL; CE13754; WBGene00020588; WP:CE13754
T20B6.3 T20B6.3 P W All gene names: T20B6.3; 3D984; CE13778; WBGene00020599; WP:CE13778
T20D3.6 T20D3.6 P W All gene names: T20D3.6; T20D3.6.1; T20D3.6.2; 4K102; CE03674; WBGene00011859; WP:CE03674
T20D3.8 T20D3.8 P W All gene names: T20D3.8; 4K106; CE23990; WBGene00011860; WP:CE23990
T20F5.2 T20F5.2 P W All gene names: pbs-4; T20F5.2; 1E477; CE13818; NM_058860; PSB2_CAEEL; WBGene00003950; WP:CE13818 WormBase description: pbs-4 encodes a B-type subunit of the 26S proteasome's 20S protease core particle; by homology, PBS-4 is predicted to function in ATP/ubiquitin-dependent nonlysosomal protein degradation; loss of pbs-4 activity via RNAi indicates that, in C. elegans, PBS-4 is required for embryonic, germline, and larval development. WormBase CDS description: peptidase
T20G5.1 T20G5.1 P W All gene names: CE-CHC; chc-1; T20G5.1; 3L297; CE00480; CLH_CAEEL; NM_066859; WBGene00011867; WP:CE00480 WormBase description: Clathrin heavy chain
T21B10.1 T21B10.1 P W All gene names: T21B10.1; 2J221; CE03683; WBGene00011883; WP:CE03683
T21B10.5 T21B10.5 P W All gene names: T21B10.5; 2J230; CE23994; WBGene00011887; WP:CE23994 WormBase description: transcriptional repressor like
T21B10.7 T21B10.7 P W All gene names: T21B10.7; T21B10.7.1; T21B10.7.2; 2J219; CE16437; TCPB_CAEEL; WBGene00011889; WP:CE16437 WormBase description: t-complex protein 1
T22C1.6 T22C1.6 P W All gene names: T22C1.6; 1I521; CE24002; WBGene00011917; WP:CE24002 WormBase description: myosin
T22F3.3 T22F3.3 P W All gene names: T22F3.3; T22F3.3b.1; T22F3.3b.2; 5E63; CE20769; CE24003; WBGene00020696; WP:CE20769; WP:CE24003 WormBase description: T22F3.3 is orthologous to the human gene MUSCLE GLYCOGEN PHOSPHORYLASE (PYGM; OMIM:232600), which when mutated leads to McArdle disease.
T22F3.4 T22F3.4 P W All gene names: rpl-11.1; T22F3.4; T22F3.4.1; T22F3.4.2; 5E64; CE13968; NM_071607; RL11_CAEEL; WBGene00004422; WP:CE13968 WormBase description: rpl-11.1 encodes a large ribosomal subunit L11 protein. WormBase CDS description: 60S ribososmal protein L11
T23B12.2 T23B12.2 P W All gene names: T23B12.2; 5I949; CE14028; O17005_CAEEL; WBGene00020717; WP:CE14028 WormBase description: ribosomal protein
T23B12.3 T23B12.3 P W All gene names: T23B12.3; 5I947; CE14030; WBGene00020718; WP:CE14030 WormBase description: ribosomal protein
T23B12.7 T23B12.7 P W All gene names: dnj-22; T23B12.7; 5I942; CE14038; NM_072777; WBGene00001040; WP:CE14038 WormBase description: This gene encodes a protein containing a DnaJ ('J') domain that is predicted to be mitochondrial.
T23B3.5 T23B3.5 P W All gene names: T23B3.5; 1H282; CE14016; WBGene00020713; WP:CE14016
T23F11.2 T23F11.2 P W All gene names: T23F11.2; 3F744; CE01095; WBGene00011954; WP:CE01095
T24B1.1 T23G11.8 P W
T23G7.5 T23G7.5 P W All gene names: pir-1; T23G7.5; 2J469; CE03706; WBGene00011967; WP:CE03706 WormBase description: tyrosine specific protein phosphatase
T24H10.3 T24H10.3 P W All gene names: dnj-23; T24H10.3; 2J398; CE03728; NM_063543; Q22751_CAEEL; WBGene00001041; WP:CE03728 WormBase description: This gene encodes a protein containing a DnaJ ('J') domain. WormBase CDS description: DNAJ protein
T24H7.1 T24H7.1 P W All gene names: phb-2; T24H7.1; 2G543; CE02883; NM_062849; PHB2_CAEEL; WBGene00004015; WP:CE02883 WormBase description: Prohibitin
T25D3.2 T25D3.2 P W All gene names: T25D3.2; 2A446; CE19599; WBGene00020796; WP:CE19599
T26A5.9 T26A5.9 P W All gene names: dlc-1; T26A5.9; T26A5.9.1; T26A5.9.2; 3H554; CE00788; DYL1_CAEEL; NM_066021; WBGene00001005; WP:CE00788 WormBase description: dlc-1 encodes a dynein light chain type 1 that affects pronuclear migrations and thus affects embryonic viability; also affects fertility, body wall morphology and integrity.
T26E3.4 T26E3.4 P W All gene names: T26E3.4; 1N259; CE24015; WBGene00012037; WP:CE24015
T27A3.4 T27A3.4 P W All gene names: T27A3.4; 1G675; CE14223; WBGene00020840; WP:CE14223
T28D9.10 T28D9.10 P W All gene names: snr-3; T28D9.10; T28D9.10.1; T28D9.10.2; T28D9.10.3; 2G778; CE02065; NM_062905; SMD1_CAEEL; WBGene00004916; WP:CE02065 WormBase description: snr-3 encodes an ortholog of human small nuclear ribonucleoprotein Sm D1, a protein that forms part of a heptameric complex required for biogenesis and function of the snRNPs that catalyze mRNA splicing; in combination with the gene that encodes the human Sm D2 ortholog (snr-4), snr-3 affects embryonic viability and nuclear association and localization of P granules in embryos, based on an RNAi assay; affects embryonic and larval viability based on large-scale RNAi assays; snr-3 is expressed in embryos and adult gonads. WormBase CDS description: small nuclear ribonucleoprotein Sm D1 (snRNP core protein D1)
T28D9.2 T28D9.2 P W All gene names: CeSC35-2; rsp-5; srp-3; T28D9.2; 2G781; CE28094; CE36572; CE36573; CE36574; NM_062906; NM_062907; NM_062908; NM_062909; RSP5_CAEEL; WBGene00004702; WP:CE28094; WP:CE36572; WP:CE36573; WP:CE36574 WormBase description: splicing factor
F26D10.3 T28F3.2 P W
VF39H2L.1 VF39H2L.1 P W All gene names: VF39H2L.1; 1J221; CE18300; WBGene00012150; WP:CE18300
W01A8.1 W01A8.1 P W All gene names: mdt-28; W01A8.1; W01A8.1b.1; W01A8.1b.2; W01A8.1b.3; 1H635; CE06531; CE18303; WBGene00007024; WP:CE06531; WP:CE18303
W01D2.1 W01D2.1 P W All gene names: W01D2.1; W01D2.1.1; W01D2.1.2; W01D2.1.3; 2P101; CE18312; WBGene00012179; WP:CE18312 WormBase description: ribosomal protein L37
W01G7.3 W01G7.3 P W All gene names: W01G7.3; 2O351; CE18986; RPO2J_CAEEL; WBGene00012187; WP:CE18986 WormBase description: RNA polymerases L / 13 to 16 Kd subunit
W02A11.1 W02A11.1 P W All gene names: W02A11.1; 1N322; CE18988; WBGene00012192; WP:CE18988
W02F12.6 W02F12.6 P W All gene names: W02F12.6; 5H190; CE31084; WBGene00020951; WP:CE31084
W03C9.5 W03C9.5 P W All gene names: W03C9.5; 2M258; CE03779; WBGene00012221; WP:CE03779
W03D2.4 W03D2.4 P W All gene names: pcn-1; W03D2.4; W03D2.4.1; W03D2.4.2; 4E812; CE37726; NM_068065; PCNA_CAEEL; WBGene00003955; WP:CE37726 WormBase description: pcn-1 encodes the C. elegans ortholog of proliferating cell nuclear antigen (PCNA), an acidic protein that is an essential component of the DNA replication and repair machinery and serves as a processivity factor for DNA polymerase delta; PCN-1 is required for early embryogenesis and for proper germ-line development, and directly interacts with CKI-2, a cyclin-dependent kinase inhibitor homolog that may be required for cell cycle progression during embryogenesis, and with ATL-1/PI3K, KIN-20, MRT-2/RAD1, and RFC-1, proteins that all play a role in the DNA damage checkpoint pathway; PCN-1 is highly expressed in ovaries and developing embryos. WormBase CDS description: cyclin
W03F8.3 W03F8.3 P W All gene names: W03F8.3; 4F953; CE17273; RF1M_CAEEL; WBGene00020993; WP:CE17273 WormBase description: protein releasing factor
W03F8.4 W03F8.4 P W All gene names: W03F8.4; 4F949; CE17274; WBGene00020994; WP:CE17274
W03F9.2 W03F9.2 P W All gene names: W03F9.2; 5A606; CE14526; CE24030; WBGene00021000; WP:CE14526; WP:CE24030
W04B5.4 W04B5.4 P W All gene names: W04B5.4; 3D496; CE20141; WBGene00021021; WP:CE20141
W04C9.4 W04C9.4 P W All gene names: W04C9.4; 1A935; CE18335; WBGene00021026; WP:CE18335
W04D2.6 W04D2.6 P W All gene names: W04D2.6; 5M983; CE32000; CE32001; WBGene00012245; WP:CE32000; WP:CE32001 WormBase description: RNA recognition motif. (aka RRM, RBD, or RNP domain)
W05F2.3 W05F2.3 P W All gene names: W05F2.3; 1D936; CE14616; WBGene00021035; WP:CE14616
W06E11.2 W06E11.2 P W All gene names: W06E11.2; 3B259; CE01427; WBGene00021062; WP:CE01427
W07E6.5 W07E6.5 P W All gene names: W07E6.5; 2A767; CE17297; WBGene00021076; WP:CE17297
W08E12.7 W08E12.C P W
W08E3.3 W08E3.3 P W All gene names: tag-210; W08E3.3; 1N935; CE14708; TG210_CAEEL; WBGene00012344; WBGene00044075; WP:CE14708 WormBase description: GTP-binding protein like
W08G11.3 W08G11.3 P W All gene names: W08G11.3; 5Q849; CE39423; CE39424; WBGene00012347; WP:CE39423; WP:CE39424
W09C5.1 W09C5.1 P W All gene names: W09C5.1; W09C5.1.1; W09C5.1.2; 1O220; CE20164; WBGene00012351; WP:CE20164
W09D10.3 W09D10.3 P W All gene names: W09D10.3; 3L797; CE16564; O18180_CAEEL; WBGene00012361; WP:CE16564 WormBase description: ribosomal protein L7/L12 mitochondrial
W09D6.6 W09D6.6 P W All gene names: haf-5; hmt-1; W09D6.6; 3M182; CE31731; NM_171229; WBGene00001815; WP:CE31731 WormBase description: haf-5 encodes a predicted transmembrane half-molecule ATP-binding cassette (ABC) transporter orthologous to Schizosaccharomyces pombe heavy metal tolerance factor 1 (SpHMT1), an ATP-dependent phytochelatin transporter; HAF-5 is required for cadmium detoxification and by homology, is predicted to promote sequestration of heavy metal-containing phytochelatins into intracellular vacuoles to protect cells from potential damage. WormBase CDS description: multidrug resistance protein (p-glycoprotein)
Y105E8B.6 Y105E8B.B P W
Y106G6A.2 Y106G6A.2 P W All gene names: Y106G6A.2; 1K508; CE30567; WBGene00013695; WP:CE30567
Y110A7A.F Y110A7A.F P W
Y110A7A.J Y110A7A.J P W
Y116A8C.42 Y116A8C.42 P W All gene names: snr-1; Y116A8C.42; 4S33; CE23346; NM_070626; SMD3_CAEEL; WBGene00004914; WP:CE23346 WormBase description: snr-1 encodes an ortholog of human small nuclear ribonucleoprotein Sm D3, a protein that forms part of a heptameric complex required for the biogenesis and function of the snRNPs that catalyze mRNA splicing; in combination with the gene that encodes the human Sm B ortholog (snr-2) snr-1 affects embryonic viability and the nuclear association and localization of P granules in embryos based on an RNAi assay, snr-1 also affects embryonic viability, growth, and fertility based on large-scale RNAi assays; snr-1 is expressed in embryos and is expressed in larvae and adults in muscles of the alimentary system, in body-wall muscle, in seam cells and other unidentified cells. WormBase CDS description: small nuclear ribonuclearprotein SM D3
Y116F11A.ZZ2 Y116F11A.ZZ2 P W
Y43F8C.8 Y116F11A.ZZ3 P W
Y119D3B.15 Y119D3_450.C P W
Y14H12B.1 Y14H12B.1 P W All gene names: Y14H12B.1; 2E225; CE21365; CE32075; CE39810; WBGene00021191; WP:CE21365; WP:CE32075; WP:CE39810 WormBase description: zinc-finger protein
Y18D10A.16 Y18D10A.16 P W All gene names: Y18D10A.16; 1N494; CE21412; WBGene00012483; WP:CE21412
Y23H5A.2 Y23H5A.2 P W All gene names: Y23H5A.2; 1D191; CE18358; WBGene00021269; WP:CE18358
Y23H5A.3 Y23H5A.3 P W All gene names: Y23H5A.3; 1D189; CE18359; WBGene00021270; WP:CE18359
Y34D9A.4 Y34D9A_151.B P W
Y37D8A.1 Y37D8A.1 P W All gene names: arx-5; Y37D8A.1; 3N906; ARPC3_CAEEL; CE20206; NM_067266; WBGene00000203; WP:CE20206 WormBase description: arx-5 encodes the C. elegans ortholog of the p21Arc subunit of the actin-related protein (Arp) 2/3 complex.
Y37D8A.10 Y37D8A.10 P W All gene names: Y37D8A.10; 3N965; CE20214; SPCS2_CAEEL; WBGene00012550; WP:CE20214
Y38A8.2 Y38A8.2 P W All gene names: pbs-3; Y38A8.2; Y38A8.2.1; Y38A8.2.2; 2F244; CE07571; NM_062512; PSB3_CAEEL; WBGene00003949; WP:CE07571 WormBase description: pbs-3 encodes a B-type subunit of the 26S proteasome's 20S protease core particle; by homology, PBS-3 is predicted to function in ATP/ubiquitin-dependent nonlysosomal protein degradation; loss of pbs-3 activity via large-scale RNAi screens indicates that, in C. elegans, PBS-3 is required for embryonic and germline development, movement, normal body coloration, and normal body morphology. WormBase CDS description: Peptidase
Y39A1A.6 Y39A1A.6 P W All gene names: Y39A1A.6; 3L707; CE19125; WBGene00012645; WP:CE19125
Y39A1A.7 Y39A1A.7 P W All gene names: Y39A1A.7; 3L708; CE19126; WBGene00012646; WP:CE19126
Y39B6A.16 Y39B6B.B P W
Y39G10AR.14 Y39G10A_246.E P W
Y39G10A_246.H Y39G10A_246.H P W
Y39H10A.7 Y39H10A_224.D P W
Y40B1B.8 Y40B1B.8 P W All gene names: Y40B1B.8; Y40B1B.8.1; Y40B1B.8.2; 1O25; CE24254; WBGene00012740; WP:CE24254
Y41E3.10 Y41E3.10 P W All gene names: Y41E3.10; 4P803; CE37568; EF1B2_CAEEL; WBGene00012768; WP:CE37568 WormBase description: Elongation factor 1 (beta/delta chain)
Y41E3.12 Y41E3.12 P W All gene names: srt-47; Y41E3.12; 4P814; CE35659; NM_070418; WBGene00012770; WP:CE35659
Y46G5A.12 Y46G5.M P W
Y46H3A.H Y46H3A.H P W
Y47D3A.29 Y47D3A.D P W
C43E11.1 Y47D9A.C P W
Y47G6A_240.D Y47G6A_240.D P W
Y48A6B.3 Y48A6B.3 P W All gene names: Y48A6B.3; Y48A6B.3.1; Y48A6B.3.2; 3M97; CE19186; NOLA2_CAEEL; WBGene00012964; WP:CE19186 WormBase description: Ribosomal protein L7Ae
Y48A6B.5 Y48A6B.5 P W All gene names: Y48A6B.5; 3M99; CE19188; WBGene00012966; WP:CE19188
Y48G1A.4 Y48G1A_54.A P W
Y48G8AL.8 Y48G8A_3945.C P W
Y49E10.15 Y49E10.15 P W All gene names: snr-6; Y49E10.15; Y49E10.O; 3N518; CE22230; NM_067219; RUXE_CAEEL; WBGene00004919; WP:CE22230 WormBase description: snr-6 encodes the C. elegans ortholog of the small nuclear ribonucleoprotein E, one of seven subunits of the heptameric Sm complex required for the biogenesis and function of snRNPs that catalyze mRNA splicing; in addition to its predicted role in pre-mRNA processing, SNR-6 activity is essential for embryogenesis and is required for several aspects of germ cell specification including cell division patterns, localization and subcellular distribution of P granules, maintenance of transcriptional quiescence, and expression of the germ lineage-specific proteins PIE-1, GLD-1, and NOS-2; snr-6 is also required for wild-type levels of fertility; immunostaining of adults and embryos using antibodies raised against mammalian Sm proteins suggests that SNR-6 localizes to the nucleus and cytoplasm in many cell types, as well as to P granules in germ cells and their embryonic precursors.
Y49E10.2 Y49E10.2 P W All gene names: Y49E10.2; Y49E10.D; 3N462; CE22220; WBGene00013029; WP:CE22220
Y49F6B.2 Y49F6B.Q P W
Y51H7C.7 Y51H7C_255.E P W
Y53C10A.2 Y53C10A.2 P W All gene names: Y53C10A.2; 1M560; CE22370; WBGene00013133; WP:CE22370
Y53F4B.22 Y53F4C.C P W
Y54E2A.3 Y54E2A.3 P W All gene names: tac-1; Y54E2A.3; 2P38; 2P40; CE20302; NM_064658; Q9XWJ0_CAEEL; WBGene00006381; WP:CE20302 WormBase description: tac-1 encodes the sole C. elegans member of the transforming acidic coiled-coil (TACC) protein family whose members contain highly conserved C-terminal coiled-coil domains; during early embryogenesis, TAC-1 activity is essential for such microtubule-based processes as pronuclear migration and mitotic spindle elongation; TAC-1 interacts in vivo with, and mutually stabilizes, ZYG-9, a microtubule-associated protein (MAP) also required for pronuclear migration; TAC-1 also interacts with ZYG-8, a kinase domain-containing MAP required for proper spindle positioning during anaphase of the first embryonic cell division; TAC-1 is a core component of centrosomes, and also localizes to the meiotic spindle poles, the mitotic spindle, and the cytoplasm.
Y54E5A.5 Y54E5A.5 P W All gene names: Y54E5A.5; Y54E5A.5.1; Y54E5A.5.2; 1P298; CE20316; WBGene00013200; WP:CE20316
Y54G9A.5 Y54G9A.5 P W All gene names: Y54G9A.5; 2O13; CE20321; WBGene00013208; WP:CE20321
Y55F3A_747.F Y55F3A_747.F P W
Y55F3BR.7 Y55F3A_747.H P W
Y55F3AM.13 Y55F3A_748.B P W
Y56A3A.18 Y56A3A.18 P W All gene names: Y56A3A.18; Y56A3A.18.1; Y56A3A.18.2; 3N8; CE22586; WBGene00013236; WP:CE22586
Y56A3A.22 Y56A3A.23 P W
Y57A10A.20 Y57A10A.R P W
Y57E12_242.C Y57E12_242.C P W
Y57G11C.3 Y57G11C.3 P W All gene names: Y57G11C.3; 4P533; 6PGL_CAEEL; CE14930; CE24473; WBGene00013301; WP:CE14930; WP:CE24473 WormBase description: SOL/DEVB family
Y61A9LA.10 Y61A9LA_74.B P W
Y62E10A.5 Y62E10A.C P W
Y62E10A.2 Y62E10A.E P W
F54D5.12 Y62F5A.E P W
Y65B4A.1 Y65B4A_174.A P W
Y65B4BR.8 Y65B4B_10.C P W
Y65B4BL.5 Y65B4B_9.B P W
Y71F9B.4 Y71F9B_286.B P W
Y71F9B.16 Y71F9B_287.B P W
Y71G12B.14 Y71G12A_187.B P W
Y71H2_388.B Y71H2_388.B P W
Y71H2_388.F Y71H2_388.F P W
Y23H5B.6 Y74C10A_150.A, Y74C10A_153.A P W
Y23H5B.6 Y74C10A_150.A, Y74C10A_153.A P W
Y75B12A.1 Y75B12A.1 P W All gene names: Y75B12A.1; 5P589; WBGene00014949
Y75B12B.2 Y75B12B.2 P W All gene names: cyn-7; cyp-7; Y75B12B.2; Y75B12B.2.1; Y75B12B.2.2; Y75B12B.2.3; 5P666; CE20371; CYP7_CAEEL; NM_074348; WBGene00000883; WP:CE20371 WormBase description: cyp-7 encodes a cyclophilin A isoform; while not tested peptidyl-prolyl isomerase activity in vitro, it is very similar to CYP-3 and closely resembles the prototypical CypA, and is therefore likely to be a member of the cytosolic CsA-binding cyclophilin subfamily; CYP-7 was required for embryonic viability in one set of mass RNAi assays. WormBase CDS description: Peptidyl-prolyl cis-trans isomerases
Y75B12B.5 Y75B12B.5 P W All gene names: cyn-3; cyp-3; Y75B12B.5; Y75B12B.5.1; Y75B12B.5.2; 5P671; CE20374; CYP3_CAEEL; NM_074350; WBGene00000879; WP:CE20374 WormBase description: cyp-3 encodes an abundantly expressed cyclophilin A isoform with peptidyl-prolyl isomerase activity in vitro, which closely resembles the prototypical CypA and is thus likely to be a member of the cytosolic CsA-binding cyclophilin subfamily; cyp-3 is exclusively expressed in the single anterior excretory cell, and is dispensable for viability and gross morphology in mass RNAi screens. WormBase CDS description: Peptidyl-prolyl cis-trans isomerases
Y75B8A.14 Y75B8A.14 P W All gene names: Y75B8A.14; 3N306; CE23026; Q9XW68_CAEEL; WBGene00013550; WP:CE23026
Y79H2A.11 Y75B8A.36 P W
Y77E11A.13 Y77E11A_3670.C P W
Y80D3A.1 Y80D3A.A P W
Y87G2A.N Y87G2A.N P W
Y87G2A.V Y87G2A.V P W
Y95D11A.1 Y95D11A.A P W
Y97E10AL.2 Y97E10A_264.A P W
ZC376.7 ZC376.7 P W All gene names: ZC376.7; ZC376.7a.1; ZC376.7a.2; ZC376.7b.1; ZC376.7b.2; 5O677; CE15205; CE32033; CE38576; WBGene00013878; WP:CE15205; WP:CE32033; WP:CE38576 WormBase description: DNA binding domain
ZC395.10 ZC395.10 P W All gene names: ZC395.10; ZC395.10.1; ZC395.10.2; 3G364; CE01436; WBGene00022599; WP:CE01436; YOCA_CAEEL
ZC404.2 ZC404.2 P W All gene names: ZC404.2; WBGene00043952
ZC410.2 ZC410.2 P W All gene names: ZC410.2; ZC410.2.1; ZC410.2.2; 4J839; CE35701; WBGene00013880; WP:CE35701 WormBase description: mitochondrial processing peptidase
ZC434.5 ZC434.5 P W All gene names: ers-2; qrs-3; ZC434.5; 1K915; CE06580; NM_060310; WBGene00001337; WP:CE06580 WormBase description: ers-2 encodes a predicted mitochondrial glutamyl-tRNA synthetase (GluRS), a class I aminoacyl-tRNA synthetase that catalyzes the attachment of glutamate to its cognate tRNA and is thus required for protein biosynthesis; ERS-2 contains, at its C-terminus, six tandemly repeated WHEP-TRS domains that have been predicted to function as general RNA-binding domains that may act as cis tRNA-binding cofactors. WormBase CDS description: glutamyl-trna synthetase
ZC487.4 ZC487.4 P W All gene names: grl-9; ZC487.4; 5H210; CE07606; NM_072305; WBGene00001718; WP:CE07606 WormBase description: grl-9 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
ZC97.1 ZC97.1 P W All gene names: tag-354; ZC97.1; 3I852; CE25677; CE33258; MTX2_CAEEL; WBGene00022516; WP:CE25677; WP:CE33258
ZK1010.3 ZK1010.3 P W All gene names: ZK1010.3; ZK1010.3.1; ZK1010.3.2; 3O69; CE37862; FRG1_CAEEL; WBGene00014177; WP:CE37862 WormBase description: FRG1-like actin crosslinking protein
ZK1058.5 ZK1058.5 P W All gene names: ZK1058.5; 3F10; CE34138; WBGene00014205; WP:CE34138
ZK1098.7 ZK1098.7 P W All gene names: ZK1098.7; ZK1098.7.1; ZK1098.7.2; 3K612; CE00566; WBGene00014224; WP:CE00566; YO67_CAEEL
ZK1127.5 ZK1127.5 P W All gene names: ZK1127.5; 2H339; CE32083; RCL1_CAEEL; WBGene00022852; WP:CE32083
ZK1127.6 ZK1127.6 P W All gene names: ZK1127.6; ZK1127.6.1; ZK1127.6.2; 2H333; CE07644; WBGene00022853; WP:CE07644
ZK1128.8 ZK1128.8 P W All gene names: ZK1128.8; ZK1128.8a.1; ZK1128.8a.2; 3L202; CE34140; CE34141; WBGene00014234; WP:CE34140; WP:CE34141
ZK121.1 ZK121.B P W
ZK1236.5 ZK1236.5 P W All gene names: ZK1236.5; 3J518; CE38925; WBGene00022864; WP:CE38925; YO85_CAEEL
ZK20.4 ZK20.4 P W All gene names: ZK20.4; 2L940; CE06607; WBGene00013925; WP:CE06607
ZK20.5 ZK20.5 P W All gene names: rpn-12; ZK20.5; 2L943; CE06608; NM_064088; PSMD8_CAEEL; WBGene00004468; WP:CE06608 WormBase description: rpn-12 is predicted to encode a non-ATPase subunit of the 19S regulatory complex of the proteasome that interacts with NHR-6 in yeast two-hybrid assays. WormBase CDS description: vegetative protein X like
ZK265.6 ZK265.6 P W All gene names: ZK265.6; 1I831; CE15299; WBGene00013958; WP:CE15299; YHHN_CAEEL
ZK287.5 ZK287.5 P W All gene names: Ce-rbx-1; rbx-1; ZK287.5; ZK287.5.1; ZK287.5.2; 5K170; CE06614; NM_073095; RBX1_CAEEL; WBGene00004320; WP:CE06614 WormBase description: The rbx-1 gene encodes an ortholog of the mammalian RING box protein RBX1 (or ROC1), which interacts with several cullins and is a subunit of both the von Hippel-Lindau (VHL) tumor suppressor complex and of the SCF ubiquitin-ligase (E3) complex. WormBase CDS description: Zinc finger, C3HC4 type (RING finger)
ZK353.8 ZK353.8 P W All gene names: ubxn-4; ZK353.8; ZK353.8.1; ZK353.8.2; 3J494; CE00392; UBXN4_CAEEL; WBGene00022703; WP:CE00392
ZK418.5 ZK418.5 P W All gene names: ZK418.5; 3I162; CE28189; WBGene00022734; WP:CE28189
ZK484.8 ZK484.8 P W All gene names: ZK484.8; ZK484.8.1; ZK484.8.2; 1G674; CE15351; WBGene00022754; WP:CE15351
ZK546.2 ZK546.2 P W All gene names: ZK546.2; 2F237; CE07632; CE36076; CE36077; WBGene00022759; WP:CE07632; WP:CE36076; WP:CE36077 WormBase description: Adenylate cyclase
ZK593.7 ZK593.7 P W All gene names: lsm-7; ZK593.7; ZK593.7.1; ZK593.7.2; 4L699; CE06628; NM_069633; WBGene00003081; WP:CE06628 WormBase description: Yeast JTA107 like
ZK632.10 ZK632.10 P W All gene names: ZK632.10; 3K918; CE02385; WBGene00014017; WP:CE02385; YOT0_CAEEL
ZK632.12 ZK632.12 P W All gene names: ZK632.12; 3K921; CE01110; WBGene00014019; WP:CE01110; YOTB_CAEEL WormBase description: PH (pleckstrin homology) domain
ZK632.8 ZK632.8 P W All gene names: arl-2; arl-5; ZK632.8; 3K913; ARL5_CAEEL; CE00425; NM_066777; WBGene00000189; WP:CE00425 WormBase description: arl-5 encodes a paralog of the ADP-ribosylation factor-like protein EVL-20; ARL-5 is an ortholog of mammalian ARL5. WormBase CDS description: ADP ribosylation factor
ZK652.1 ZK652.1 P W All gene names: snr-5; ZK652.1; ZK652.1.1; ZK652.1.2; 3I953; CE00446; NM_066307; RUXF_CAEEL; WBGene00004918; WP:CE00446 WormBase description: snr-5 encodes an ortholog of human small nuclear ribonucleoprotein SmF, a protein that forms part of a heptameric complex required for biogenesis and function of the snRNPs that catalyze mRNA splicing; in combination with the gene that encodes the human SmE and SmG orthologs (snr-6 and snr-7, respectively), snr-5 affects embryonic viability and nuclear association and localization of P granules in embryos, based on an RNAi assay; affects embryonic and larval viability based on large-scale RNAi assays; snr-5 is expressed in embryos and adult gonads. WormBase CDS description: small nuclear ribonucleoprotein Sm F (snRNP core protein F)
ZK652.2 ZK652.2 P W All gene names: tomm-7; ZK652.2; 3I951; CE00448; NM_066305; TOM7_CAEEL; WBGene00022783; WP:CE00448
ZK652.4 ZK652.4 P W All gene names: rpl-35; ZK652.4; ZK652.4.1; ZK652.4.2; ZK652.4.3; ZK652.4.4; ZK652.4.5; ZK652.4.6; 3I945; CE00450; NM_066301; RL35_CAEEL; WBGene00004449; WP:CE00450 WormBase description: rpl-35 encodes a large ribosomal subunit L35 protein. WormBase CDS description: 60S ribosomal protein L35
ZK686.1 ZK686.1 P W All gene names: ZK686.1; 3I863; CE34463; WBGene00022791; WP:CE34463; YO11_CAEEL WormBase description: ATP-dependent RNA helicase
ZK742.5 ZK742.5 P W All gene names: lbp-4; ZK742.5; 5I301; CE07641; FABP4_CAEEL; NM_072615; WBGene00002256; WP:CE07641 WormBase description: lpb-4 encodes a homolog of the novel fatty acid binding protein, As-p18, found in the parasitic nematode Ascaris suum; As-p18 is a member of a family of small intracellular fatty acid binding proteins (iFABPs); unlike most lpb family members lpb-4 lacks a secretory signal
ZK84.1 ZK84.1 P W All gene names: ZK84.1; 2G313; CE02924; WBGene00022649; WP:CE02924
ZK856.10 ZK856.10 P W All gene names: ZK856.10; 5K686; CE06667; WBGene00014111; WP:CE06667 WormBase description: DNA directed RNA polymerase III
ZK856.11 ZK856.11 P W All gene names: ZK856.11; 5K684; CE06668; Q23646_CAEEL; WBGene00014112; WP:CE06668
ZK863.6 ZK863.6 P W All gene names: dpy-30; ZK863.6; ZK863.6.1; ZK863.6.2; ZK863.6.3; 5M671; CE15445; DPY30_CAEEL; NM_073657; WBGene00001088; WP:CE15445 WormBase description: The dpy-30 gene encodes an essential nuclear protein required for hermaphrodite dosage compensation as well as normal male development; DPY-30 is expressed ubiquitously throughout development and can be detected in two different multiprotein complexes: the SDC complex involved in dosage compensation and a second complex containing NOX-1 (a WD repeat-containing protein) and ASH-2 (a trithorax-related protein) that is homologous to the yeast Set1p complex involved in epigenetic regulation of transcription. WormBase CDS description: DPY-30 protein
ZK945.2 ZK945.2 P W All gene names: pas-7; ZK945.2; ZK945.2.1; ZK945.2.2; 2K388; CE36420; NM_063776; PSA3_CAEEL; WBGene00003928; WP:CE36420 WormBase description: proteasome component (A-type)
ZK945.3 ZK945.3 P W All gene names: ZK945.3; 2K391; CE01734; WBGene00014165; WP:CE01734; YS83_CAEEL WormBase description: pumilio-repeat like domain
ZK970.3 ZK970.3 P W All gene names: mdt-22; ZK970.3; 2K591; CE02403; MED22_CAEEL; NM_063815; WBGene00007022; WP:CE02403
ZK973.11 ZK973.A P W