Denver et al 2005, differentially expressed in MA, 662 genes

Gene list file name:Denver2005_ST1_differential-genes_in_MAlines
Type of gene identifier:MA primer pair (sjj)
Description:Denver et al 2005 Supplement Table 1: 662 genes that differentially expressed in MA(Mutation Accumulation) lines.  
Organism:Caenorhabditis elegans (nematode)
Gene list type:Experimental

Gene name             Source Gene ID          Annotation                                                  Date       Added by    

AC3.7 AC3.7 P W All gene names: dod-15; ugt-1; AC3.7; 5K877; CE05137; NM_073270; WBGene00007072; WP:CE05137 WormBase description: UDP-glucuronosyltransferase
AH10.1 AH10.1 P W All gene names: AH10.1; 5O629; CE07655; WBGene00007082; WP:CE07655 WormBase description: 4-coumarate:coenzyme A ligase
B0024.1 B0024.1 P W All gene names: col-149; B0024.1; 5K772; CE05146; NM_073245; Q17417_CAEEL; WBGene00000722; WP:CE05146 WormBase description: collagen
B0035.4 B0035.4 P W All gene names: tag-317; B0035.4; B0035.4.1; B0035.4.2; B0035.4.3; 4M79; 4M81; CE05162; PFD4_CAEEL; WBGene00007107; WP:CE05162 WormBase description: paramyosin like
B0218.7 B0218.7 P W All gene names: B0218.7; 4I930; CE06690; WBGene00015051; WP:CE06690
B0222.6 B0222.6 P W All gene names: col-144; B0222.6; 5J640; CE30585; NM_072973; WBGene00000717; WP:CE30585
B0222.7 B0222.7 P W All gene names: col-145; B0222.7; 5J642; CE06698; NM_072974; WBGene00000718; WP:CE06698
B0222.8 B0222.8 P W All gene names: col-10; B0222.8; 5J644; CE06699; NM_072975; WBGene00000599; WP:CE06699 WormBase description: col-10 encodes a collagen protein; expressed exclusively in hypodermal cells
B0228.1 B0228.1 P W All gene names: B0228.1; 2I45; CE01742; WBGene00015059; WP:CE01742; YP71_CAEEL
B0261.6 B0261.6 P W All gene names: B0261.6; 1F824; CE29532; CE39549; WBGene00015094; WP:CE29532; WP:CE39549
C23F12.1 B0272.5 P W
B0273.1 B0273.1 P W All gene names: B0273.1; 4G259; CE16787; WBGene00015097; WP:CE16787
B0310.5 B0310.5 P W All gene names: ugt-46; B0310.5; CE03878; UGT46_CAEEL; WBGene00015141; WP:CE03878; XB146 WormBase description: 7TM chemoreceptor, ugt family
B0365.3 B0365.3 P W All gene names: eat-6; spa-1; B0365.3; B0365.3.1; B0365.3.2; 5N608; CE07721; NM_073868; NaK/1; WBGene00001137; WP:CE07721 WormBase description: eat-6 encodes an ortholog of the alpha subunit of a sodium/potassium ATPase, which in turn affects Na+,K(+)-ATPase activity of membranes by affecting the level of the phosphorylated intermediate of the Na+,K(+)-ATPase; EAT-6 affects relaxation of the pharyngeal muscles, fertility (and thus affects feeding); EAT-6 also affects body length, life span, and ASE, ASI and ASJ axonal outgrowth. WormBase CDS description: Na(+)/K(+) ATPase alpha subunit
B0365.6 B0365.6 P W All gene names: clec-41; B0365.6; B0365.6.1; B0365.6.2; B0365.6.3; 5N616; CE07723; WBGene00007153; WP:CE07723 WormBase description: C-type lectin domain
B0379.2 B0379.2 P W All gene names: B0379.2; 1K644; CE07725; WBGene00007156; WP:CE07725
B0464.2 B0464.2 P W All gene names: B0464.2; 3K585; CE20456; WBGene00007184; WP:CE20456; YKD1_CAEEL WormBase description: TPR Domain
B0464.3 B0464.3 P W All gene names: nlp-36; B0464.3; B0464.3.1; B0464.3.2; 3K579; CE00017; NLP36_CAEEL; WBGene00007185; WP:CE00017
B0491.3 B0491.3 P W All gene names: B0491.3; 2L628; CE02105; WBGene00007190; WP:CE02105
B0507.3 B0507.3 P W All gene names: B0507.3; 5J251; CE07762; CE39664; WBGene00015220; WP:CE07762; WP:CE39664
C01B10.1 C01B10.1 P W All gene names: drh-2; C01B10.1; 4H380; CE33024; NM_068618; WBGene00001091; WP:CE33024
C01F6.2 C01F6.2 P W All gene names: C01F6.2; CE26968; WBGene00007222; WP:CE26968
C01G5.3 C01G5.3 P W All gene names: C01G5.3; 4H301; CE06749; WBGene00015305; WP:CE06749
C01G6.3 C01G6.3 P W All gene names: C01G6.3; 2J561; CE37474; WBGene00007225; WP:CE37474
C02A12.4 C02A12.4 P W All gene names: lys-7; C02A12.4; 5D960; CE07828; NM_071571; WBGene00003096; WP:CE07828 WormBase description: lys-7 encodes an enzyme homologous to an antimicrobial lysozyme encoded by the LYS4 gene of the protozoan parasite Entamoeba histolytica; by homology, LYS-7 is predicted to function as an antimicrobial enzyme that hydrolyzes the 1,4-beta-linkages between N-acetyl-D-glucosamine and N-acetylmuramic acid in peptidoglycan heteropolymers of prokaryotic cell walls; in C. elegans, lys-7 expression is significantly upregulated in response to infection with the Gram-negative bacterium Serratia marcescens, indicating that LYS-7 likely plays a role in the innate immune response; constitutive expression of lys-7 mRNA is detected in the intestine and the intestinal valve cells.
C02B10.6 C02B10.6 P W All gene names: C02B10.6; 4F837; CE20481; WBGene00015331; WP:CE20481
C02E7.6 C02E7.6 P W All gene names: C02E7.6; 5F397; CE07843; WBGene00015339; WP:CE07843
C02E7.7 C02E7.7 P W All gene names: C02E7.7; 5F396; CE07844; WBGene00015340; WP:CE07844
C03C10.3 C03C10.3 P W All gene names: rnr-2; C03C10.3; C03C10.3.1; C03C10.3.2; C03C10.3.3; 3F184; CE00874; NM_065420; RIR2_CAEEL; WBGene00004392; WP:CE00874 WormBase description: Ribonuclease-diphosphate reductase M2
C03C11.1 C03C11.1 P W All gene names: C03C11.1; 1K591; CE07873; WBGene00007274; WP:CE07873
C03F11.3 C03F11.3 P W All gene names: C03F11.3; CE37606; WBGene00015389; WP:CE37606; XG16; YX13_CAEEL WormBase description: glycoprotein
C04F12.7 C04F12.7 P W All gene names: C04F12.7; 1K272; CE19680; WBGene00007301; WP:CE19680
C04G2.4 C04G2.4 P W All gene names: msp-36; C04G2.4; 4K861; NM_069433; WBGene00003432 WormBase description: msp-36 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family comprises of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSP is involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP assembles into fibrous networks that drives movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. WormBase CDS description: major sperm protein
C04G2.8 C04G2.8 P W All gene names: C04G2.8; 4K876; CE05216; WBGene00007307; WP:CE05216
C04G2.9 C04G2.9 P W All gene names: C04G2.9; 4K879; CE05217; WBGene00007308; WP:CE05217
C05A9.1 C05A9.1 P W All gene names: pgp-5; C05A9.1; CE05221; NM_077409; WBGene00003999; WP:CE05221; XL474 WormBase description: pgp-5 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; by homology, PGP-5 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins; however, as loss of pgp-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-5 in C. elegans development and/or behavior is not yet known. WormBase CDS description: p-glycoprotein
C05B5.2 C05B5.2 P W All gene names: C05B5.2; 3L90; CE00878; WBGene00007320; WP:CE00878; YKO2_CAEEL
C05C12.1 C05C12.1 P W All gene names: C05C12.1; 4M19; CE02965; WBGene00007335; WP:CE02965 WormBase description: serine/threonine kinase
C05C8.3 C05C8.3 P W All gene names: dao-1; fkb-3; C05C8.3; 5H707; CE07921; NM_072434; WBGene00001428; WP:CE07921 WormBase description: fkb-3 encodes a peptidylprolyl cis/trans isomerase homologous to mammalian FK506 immunosuppressant-binding protein 9; FKB-3 expression is positively regulated by signaling through the DAF-2 insulin receptor-like pathway and the activity of the DAF-16 fork-head transcription factor suggesting that FKB-3 could play a role in metabolism and longevity; however, as loss of FKB-3 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of FKB-3 in C. elegans development and/or behavior is not yet known; FKB-3 contains a predicted endoplasmic reticulum (ER) retention sequence and is thus proposed to localize to the ER. WormBase CDS description: FKBP-binding protein
C06A1.3 C06A1.3 P W All gene names: C06A1.3; 2K863; CE02116; WBGene00007354; WP:CE02116; YT91_CAEEL WormBase description: serine/threonine protein phosphatase
C06A8.6 C06A8.6 P W All gene names: C06A8.6; 2I63; CE02457; WBGene00015516; WP:CE02457
C06B3.6 C06B3.6 P W All gene names: C06B3.6; 5O390; CE07963; WBGene00007365; WP:CE07963
C06G1.1 C06G1.1 P W All gene names: C06G1.1; CE27054; WBGene00015545; WP:CE27054; XR251
C06G1.2 C06G1.2 P W All gene names: C06G1.2; CE03965; WBGene00015546; WP:CE03965; XR239
C07B5.5 C07B5.5 P W All gene names: nuc-1; C07B5.5; CE00895; NM_077203; NUC1_CAEEL; WBGene00003828; WP:CE00895; XK159 WormBase description: The nuc-1 gene encodes a DNase II homolog similar to mammalian and Drosophila DNaseII enzymes and is required for DNA degradation during apoptosis as well as for degradation of dietary DNA during normal feeding; during apoptosis, NUC-1 functions in apoptotic cells at an intermediate stage of DNA degradation, after the killing step, but prior to cell-corpse engulfment.
C07D8.6 C07D8.6 P W All gene names: C07D8.6; C07D8.6.1; C07D8.6.2; CE06776; WBGene00015565; WP:CE06776; XH961 WormBase description: aldehyde reductase
C08B11.1 C08B11.1 P W All gene names: zyg-11; C08B11.1; 2I309; CE01471; NM_063276; WBGene00006996; WP:CE01471; ZYG11_CAEEL WormBase description: Leucine Rich Repeat (2 copies)
C08B11.4 C08B11.4 P W All gene names: nrf-6; C08B11.4; 2I320; CE27798; NM_063279; NRF6_CAEEL; WBGene00003813; WP:CE27798 WormBase description: nrf-6 encodes a protein with 12 predicted transmembrane domains that is highly similar to NDG-4 and affects embryonic viability, yolk transport, locomotion, body morphology, and affects sensitivity to fluoxetine with respect to nose-contraction response in a common pathway with ndg-4 and nrf-5; expressed in the most anterior cells of the hypodermis and in the intestine and is required in the intestine for fluoxetine-induced nose contraction and yolk transport
C08B6.3 C08B6.3 P W All gene names: C08B6.3; 5K592; CE05240; WBGene00007424; WP:CE05240
C09F12.1 C09F12.1 P W All gene names: clc-1; C09F12.1; CE08040; NM_077446; WBGene00000522; WP:CE08040; XL667 WormBase description: clc-1 encodes a claudin homolog, closely similar to CLC-2, that is required for normal cohesion of apical junctions in epithelia; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water; CLC-1 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the pharynx to dyes; clc-1 is expressed in spermatheca, pharynx, intestine, hypodermis, the excretory-secretory system, and the cell-cell junctions of the vulva; in pharyngeal cells, CLC-1 colocalizes with AJM-1 in long thin lines, parallel to the pharyngeal axis and lining the lumenal surface, that appear to correspond with apical intercellular junctions.
C09G1.1 C09G1.1 P W All gene names: pqn-11; C09G1.1; CE37313; NM_078217; Q17862_CAEEL; WBGene00004103; WP:CE37313; XQ582 WormBase description: PQN-11 encodes an unfamiliar protein with a glutamine/asparagine-rich domain that is dispensable for viability and gross morphology.
C09G5.3 C09G5.3 P W All gene names: col-79; C09G5.3; 2K993; CE01483; COL79_CAEEL; NM_063907; WBGene00000655; WP:CE01483 WormBase description: collagen
C09G5.5 C09G5.5 P W All gene names: col-80; C09G5.5; 2K997; CE01485; COL80_CAEEL; NM_063909; WBGene00000656; WP:CE01485 WormBase description: collagen
C09G5.6 C09G5.6 P W All gene names: bli-1; C09G5.6; 2L1; BLI1_CAEEL; CE35827; NM_063910; WBGene00000251; WP:CE35827 WormBase description: The bli-1 gene encodes an unusual cuticular collagen that is required for proper strut formation within the unique medial layer of the adult cuticle; bli-1 interacts genetically with other cuticular collagens such as bli-2 and rol-1, and may be processed for secretion by BLI-4, a Kex2/subtilisin serine endoproteinase; consistent with its role in adult cuticle formation, bli-1 mRNA is highly expressed only during the L4 larval stage. WormBase CDS description: collagen
C10G11.9 C10G11.9 P W All gene names: C10G11.9; 1G850; CE08088; WBGene00015689; WP:CE08088
C10G8.4 C10G8.4 P W All gene names: C10G8.4; 5F789; CE08075; WBGene00015683; WP:CE08075
C11E4.2 C11E4.2 P W All gene names: C11E4.2; CE08102; GPX3_CAEEL; WBGene00007517; WP:CE08102; XK205 WormBase description: glutathione peroxidase
C12D12.1 C12D12.1 P W All gene names: C12D12.1; CE27679; CE29576; WBGene00015713; WP:CE27679; WP:CE29576; XE123
C12D5.7 C12D5.7 P W All gene names: cyp-33A1; C12D5.7; 5I160; CE06809; NM_072587; WBGene00015709; WP:CE06809 WormBase description: cytochrome P450
C12D8.11 C12D8.11 P W All gene names: rop-1; C12D8.11; C12D8.11.1; C12D8.11.2; 5K734; CE15613; NM_073237; RO60_CAEEL; WBGene00004405; WP:CE15613; rop1 WormBase description: rop-1 encodes an RNAi-binding protein that is orthologous to the vertebrate 60-kDa Ro autoantigen that is the protein component of the Ro ribonucleoprotein (RNP) complex; ROP-1 binds the single C. elegans Ro RNP RNA component, YRN-1 (Y RNA) in vivo and although loss of rop-1 activity via mutation results in no obvious visible phenotypes, it does result in a dramatic decrease in YRN-1 levels, indicating that ROP-1 is necessary for maintaining normal levels of the Ro RNP Y RNA; in addition, rop-1 mutations also result in a statistically significant increase in mutant 5S rRNA molecules found in ribosomal RNA preparations, suggesting that ROP-1 may play a role in quality control of 5S rRNA processing; rop-1 mRNA is detectable during all stages of development, and rop-1 promoter fusions appear to be expressed in all cell types, except the germline. WormBase CDS description: ROP-1 ribonucleoprotein RO autoantigen
C14A6.1 C14A6.1 P W All gene names: clec-48; C14A6.1; 5S639; CE18493; WBGene00007565; WP:CE18493 WormBase description: Lectin C-type domain short and long forms (2 domains)
C14B9.4 C14B9.4 P W All gene names: plk-1; C14B9.4; C14B9.4a.1; C14B9.4a.2; 3J193; CE26649; CE30602; PLK1_CAEEL; WBGene00004042; WP:CE26649; WP:CE30602; plc1 WormBase description: plk-1 encodes a serine/threonine polo-like kinase homologous to Drosophila polo and Saccharomyces cerevisiae CDC5; PLK-1 is required for meiotic nuclear envelope breakdown, polar body formation and extrusion, and proper chromosome segregation during meiosis, and additionally, may play a role in germline development; PLK-1 is proposed to phosphorylate REC-8, a meiotic-specific cohesin, thus promoting REC-8 degradation and subsequent separation of sister chromatids; PLK-1 is localized diffusely in the cytoplasm of mature oocytes, but during meiosis I becomes associated with pre-metaphase chromatin and then at anaphase with chromatin and the area between dividing chromatin; in embryos, PLK-1 localizes to centrosomes, metaphase chromatin, and during telophase, to the area between dividing chromatin.
C14C10.1 C14C10.1 P W All gene names: C14C10.1; 5N69; CE05280; WBGene00007584; WP:CE05280 WormBase description: mitochondrial carrier protein
C14C11.1 C14C11.1 P W All gene names: C14C11.1; 5G145; CE06820; WBGene00015765; WP:CE06820
C14F11.4 C14F11.4 P W All gene names: C14F11.4; CE37197; CE37198; WBGene00015780; WP:CE37197; WP:CE37198; XG850
C15C7.5 C15C7.5 P W All gene names: C15C7.5; CE03991; WBGene00015791; WP:CE03991; XD770
C15F1.2 C15F1.H P W
C16B8.3 C16B8.3 P W All gene names: C16B8.3; C16B8.3.1; C16B8.3.2; CE04013; Q18043_CAEEL; WBGene00015823; WP:CE04013; XE586
C16H3.2 C16H3.2 P W All gene names: lec-9; C16H3.2; CE08236; NM_078443; WBGene00002272; WP:CE08236; XS215 WormBase description: lec-9 encodes a predicted lectin that affects embryonic viability. WormBase CDS description: sugar-binding protein
C17E7.9 C17E7.9 P W All gene names: C17E7.9; 5E368; CE27700; CE27701; WBGene00015903; WP:CE27700; WP:CE27701
C17F4.5 C17F4.5 P W All gene names: C17F4.5; 2D538; CE27075; WBGene00015912; WP:CE27075 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
C17H12.3 C17H12.3 P W All gene names: C17H12.3; 4H558; CE16864; WBGene00015929; WP:CE16864 WormBase description: protein-tyrosine phosphatase
C17H12.8 C17H12.8 P W All gene names: C17H12.8; 4H583; CE19360; WBGene00015933; WP:CE19360
C18E9.1 C18E9.1 P W All gene names: cal-2; C18E9.1; 2J251; CE34702; NM_063505; WBGene00000286; WP:CE34702 WormBase description: cal-2 encodes a calmodulin homolog required for embryonic development or viability; CAL-2 is closely similar to its paralogs CAL-1, CAL-3, CAL-4 and CMD-1. WormBase CDS description: calmodulin
C18E9.9 C18E9.9 P W All gene names: C18E9.9; 2J278; CE05301; Q18089_CAEEL; WBGene00007689; WP:CE05301
C18G1.9 C18G1.9 P W All gene names: C18G1.9; 5F242; CE17425; WBGene00015987; WP:CE17425
C18H7.4 C18H7.4 P W All gene names: C18H7.4; 4B347; CE17429; WBGene00015994; WP:CE17429 WormBase description: protein kinase
C24D10.2 C24D10.2 P W All gene names: C24D10.2; 4F929; CE16875; WBGene00016054; WP:CE16875
C24D10.7 C24D10.7 P W All gene names: C24D10.7; 4F928; CE16879; WBGene00016058; WP:CE16879
C25A11.4 C25A11.4 P W All gene names: ajm-1; jam-1; C25A11.4; CE27083; CE27084; CE27085; CE30874; CE39677; NM_077135; NM_077136; NM_077137; NM_171966; WBGene00000100; WP:CE27083; WP:CE27084; WP:CE27085; WP:CE30874; WP:CE39677; XJ731 WormBase description: ajm-1 encodes a member of the apical junction molecule class that is required for correct elongation of the C. elegans embryo; AJM-1 contains a coiled-coil motif; AJM-1 binds DLG-1 in vitro, in yeast two-hybrid assays, and in vivo; AJM-1 is mislocalized in a dlg-1(RNAi) background; LET-413 is required for rapid confinement of DLG-1 and AJM-1 to a narrow apical region in C. elegans epithelia; CLC-1 colocalizes with AJM-1; vab-9 mutations enhance the adhesion defects of ajm-1 mutants; ajm-1 is expressed at the apical borders of all epithelia.
C25D7.1 C25D7.1 P W All gene names: C25D7.1; 5P516; CE08387; WBGene00007714; WP:CE08387
C25D7.2 C25D7.2 P W All gene names: C25D7.2; 5P518; CE08388; WBGene00007715; WP:CE08388
C25G4.6 C25G4.6 P W All gene names: C25G4.6; 4N221; CE05307; WBGene00007733; WP:CE05307 WormBase description: PDZ domain (Also known as DHR or GLGF). (2 domains)
C26B9.3 C26B9.3 P W All gene names: C26B9.3; CE29187; WBGene00016133; WP:CE29187; XF957
C26B9.5 C26B9.5 P W All gene names: C26B9.5; CE04098; WBGene00016134; WP:CE04098; XF949 WormBase description: lysosomal Pro-X carboxypeptidase
C26F1.1 C26F1.1 P W All gene names: C26F1.1; 5I267; CE32807; CE35249; WBGene00016146; WP:CE32807; WP:CE35249
C27D6.3 C27D6.3 P W All gene names: C27D6.3; 2F464; CE01813; WBGene00016161; WP:CE01813; YQ93_CAEEL WormBase description: MST101-2 protein (Fruit Fly)
C27D8.1 C27D8.1 P W All gene names: C27D8.1; 4N483; CE18539; WBGene00007777; WP:CE18539 WormBase description: serine/threonine kinase
C27D8.2 C27D8.2 P W All gene names: C27D8.2; 4N479; CE08421; WBGene00007778; WP:CE08421
C28A5.6 C28A5.6 P W All gene names: C28A5.6; 3F514; CE00673; WBGene00007791; WP:CE00673 WormBase description: serine/threonine kinase
C28C12.7 C28C12.6, C28C12.7 P W All gene names: spp-10; C28C12.7; C28C12.7a.1; C28C12.7a.2; 4J243; CE29486; CE31323; NM_171399; NM_171400; WBGene00004995; WP:CE29486; WP:CE31323 WormBase description: spp-10 encodes two protein isoforms that are orthologous to the human gene PROSAPOSIN (PSAP; OMIM:176801, mutated in Gaucher disease and metachromatic leukodystrophy); SPP-10A and -10B are predicted to have 3 and 4 embedded saposin sequences, that are likely to be split into individual saposin peptides by proteolysis; in mammals, saposins activate the enzymes sphingomyelinphosphodiesterase and beta-glucosylceramidase; spp-10 has no obvious function in mass RNAi assays. WormBase CDS description: 7TM chemoreceptor, spp family
C28C12.7 C28C12.6, C28C12.7 P W All gene names: spp-10; C28C12.7; C28C12.7a.1; C28C12.7a.2; 4J243; CE29486; CE31323; NM_171399; NM_171400; WBGene00004995; WP:CE29486; WP:CE31323 WormBase description: spp-10 encodes two protein isoforms that are orthologous to the human gene PROSAPOSIN (PSAP; OMIM:176801, mutated in Gaucher disease and metachromatic leukodystrophy); SPP-10A and -10B are predicted to have 3 and 4 embedded saposin sequences, that are likely to be split into individual saposin peptides by proteolysis; in mammals, saposins activate the enzymes sphingomyelinphosphodiesterase and beta-glucosylceramidase; spp-10 has no obvious function in mass RNAi assays. WormBase CDS description: 7TM chemoreceptor, spp family
C28D4.7 C28D4.4 P W
C28D4.8 C28D4.5 P W
C29E4.1 C29E4.1 P W All gene names: col-90; C29E4.1; 3J39; CE00083; COL90_CAEEL; NM_066328; WBGene00000665; WP:CE00083 WormBase description: Cuticle collagen
C29E4.4 C29E4.4 P W All gene names: npp-15; C29E4.4; 3J21; CE37484; CeNup133; NM_066323; NU133_CAEEL; WBGene00003801; WP:CE37484
C29E6.3 C29E6.3 P W All gene names: pph-2; pph2A-c; C29E6.3; 4M640; CE17478; NM_069850; WBGene00004084; WP:CE17478 WormBase description: protein tyrosine phosphatase
C29F4.1 C29F4.1 P W All gene names: col-125; C29F4.1; C29F4.1.1; C29F4.1.2; 4L991; CE03038; NM_069706; WBGene00000699; WP:CE03038 WormBase description: collagen
C29F9.2 C29F9.2 P W All gene names: C29F9.2; 3A339; 3A749; CE08450; WBGene00016217; WP:CE08450
C30B5.4 C30B5.4 P W All gene names: C30B5.4; 2G486; CE02523; Q18318_CAEEL; WBGene00016245; WP:CE02523 WormBase description: Probable RNA binding protein
C30H6.5 C30H6.5 P W All gene names: C30H6.5; 4S317; CE15649; WBGene00007823; WP:CE15649
C31C9.1 C31C9.1 P W All gene names: tag-10; C31C9.1; 2N925; CE32597; CE32598; WBGene00006404; WP:CE32597; WP:CE32598 WormBase description: tag-10 encodes, by alternative splicing, two nearly identical proteins; TAG-10 proteins are putatively secreted, with an N-terminal signal sequence and four C-terminal WD40 repeats; TAG-10 proteins are orthologous to the GA1 apical gut membrane polyprotein of Haemonchus contortus, and more distantly similar to the periplasmic TolB colicin receptor subunit of E. coli.
C31H5.6 C31H5.6 P W All gene names: C31H5.6; 1J620; CE17486; WBGene00007857; WP:CE17486
C32E12.1 C32E12.1 P W All gene names: C32E12.1; 1F803; CE04133; WBGene00016327; WP:CE04133
C32E8.4 C32E8.4 P W All gene names: C32E8.4; 1E353; CE29692; WBGene00016322; WP:CE29692
C32F10.5 C32F10.5 P W All gene names: hmg-3; C32F10.5; 1G392; CE08542; NM_059287; SSP1B_CAEEL; WBGene00001973; WP:CE08542 WormBase description: single-strand recognition protein
C33A12.6 C33A12.6 P W All gene names: ugt-21; C33A12.6; 4K263; CE05352; WBGene00007885; WP:CE05352 WormBase description: UDP-glucuronysltransferase
C33F10.12 C33F10.12 P W All gene names: C33F10.12; 2F126; CE04144; WBGene00016358; WP:CE04144 WormBase description: mitochondrial phosphate carrier protei
C33G8.1 C33G8.1 P W All gene names: srw-127; C33G8.1; 5H495; CE34730; NM_072375; WBGene00005874; WP:CE34730 WormBase description: 7TM chemoreceptor, srw family
C33H5.13 C33H5.13 P W All gene names: C33H5.13; 4I556; CE04156; WBGene00016379; WP:CE04156
C34D1.5 C34D1.5 P W All gene names: C34D1.5; 5N749; CE18541; WBGene00007932; WP:CE18541 WormBase description: Basic region plus leucine zipper transcription factors
C34D4.9 C34D4.9 P W All gene names: nas-8; C34D4.9; 4H881; CE31327; NAS8_CAEEL; NM_068713; WBGene00003527; WP:CE31327
C34F11.4 C34F11.4 P W All gene names: msp-50; C34F11.4; 2F491; NM_062571; WBGene00003443 WormBase description: msp-50 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. WormBase CDS description: major sperm protein
C34F11.6 C34F11.6 P W All gene names: msp-49; C34F11.6; 2F485; CE04166; MSP49_CAEEL; NM_062569; WBGene00003442; WP:CE04166 WormBase description: msp-49 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. WormBase CDS description: major sperm protein
C34H4.1 C34H4.1 P W All gene names: C34H4.1; 4C321; CE25804; WBGene00016424; WP:CE25804
C35A5.8 C35A5.8 P W All gene names: C35A5.8; 5L4; CE15680; WBGene00007952; WP:CE15680
C35B1.5 C35B1.5 P W All gene names: C35B1.5; C35B1.5.1; C35B1.5.2; C35B1.5.3; 4E848; CE16903; WBGene00016435; WP:CE16903
C35D10.2 C35D10.2 P W All gene names: C35D10.2; 3F961; CE01196; Q18488_CAEEL; WBGene00016440; WP:CE01196
C36A4.2 C36A4.2 P W All gene names: cyp-25A2; C36A4.2; 3E925; CE37617; NM_065375; WBGene00007964; WP:CE37617 WormBase description: cytochrome P450
C36F7.5 C36F7.5 P W All gene names: C36F7.5; 1K150; CE08609; WBGene00007986; WP:CE08609
E02D9.1 C37A2.1 P W
C37A2.3 C37A2.3 P W All gene names: C37A2.3; 1H361; CE08612; WBGene00016491; WP:CE08612 WormBase description: acyl-CoA dehydrogenase
C38C3.3 C38C3.3 P W All gene names: C38C3.3; 5B975; CE29711; WBGene00016512; WP:CE29711
C38C6.6 C38C6.6 P W All gene names: tag-297; C38C6.6; C38C6.6.1; C38C6.6.2; 2O915; CE15698; WBGene00007999; WP:CE15698
C39H7.1 C39H7.1 P W All gene names: C39H7.1; 4G397; CE06942; WBGene00016541; WP:CE06942 WormBase description: casein kinase
C40H5.1 C40H5.1 P W All gene names: nspa-9; C40H5.1; CE08649; WBGene00043187; WP:CE08649
C41G7.6 C41G7.6 P W All gene names: C41G7.6; 1K102; CE17540; WBGene00008063; WP:CE17540
C43E11.5 C43E11.5 P W All gene names: C43E11.5; 1E807; CE08683; WBGene00016605; WP:CE08683
C43E11.6 C43E11.6 P W All gene names: nab-1; C43E11.6; C43E11.6d.1; C43E11.6d.2; C43E11.6d.3; C43E11.6e.1; C43E11.6e.2; 1E803; CE08684; CE27846; CE27847; CE29717; CE37753; NM_058931; NM_058932; NM_058933; NM_171836; WBGene00003516; WP:CE08684; WP:CE27846; WP:CE27847; WP:CE29717; WP:CE37753 WormBase description: nab-1 encodes a PDZ and SAM domain-containing protein that is the sole C. elegans ortholog of the mammalian Neurabin/Spinophilin proteins; by homology, NAB-1 is predicted to interact with F-actin, ZYG-8/Doublecortin and the SAD-1 serine/threonine kinase to regulate interactions between the actin and microtubule networks during cell migration, growth cone guidance, and cell division; loss of nab-1 activity via RNAi has been reported to result in early embryonic lethality, dumpy and left-handed roller animals, as well as abnormalities in germ-line development and vulval morphogenesis; in large-scale screens, nab-1 RNAi did not result in any obvious abnormalities; NAB-1 translational reporter fusions show expression in hypodermal cells, neurons, and muscle.
C43F9.6 C43F9.6 P W All gene names: C43F9.6; 4L357; CE19734; WBGene00008074; WP:CE19734 WormBase description: Sodium and potassium ATPases
C43G2.3 C43G2.3 P W All gene names: C43G2.3; 4H343; CE36277; WBGene00016612; WP:CE36277
C44B7.8 C44B7.8 P W All gene names: pmp-1; C44B7.8; 2H172; CE02546; NM_063006; WBGene00004058; WP:CE02546 WormBase description: ATP-binding protein
C44C8.4 C44C8.4 P W All gene names: C44C8.4; 4B645; CE17543; WBGene00016649; WP:CE17543 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
C44E4.3 C44E4.3 P W All gene names: C44E4.3; 1F206; CE34271; WBGene00016652; WP:CE34271 WormBase description: aminotransferase
C45G9.4 C45G9.4 P W All gene names: C45G9.4; 3G153; CE01855; WBGene00016675; WP:CE01855; YQI4_CAEEL
C45G9.9 C45G9.9 P W All gene names: C45G9.9; 3G144; CE01860; WBGene00016680; WP:CE01860; YQI9_CAEEL
C47A4.3 C47A4.3 P W All gene names: C47A4.3; 4O506; CE19739; WBGene00008124; WP:CE19739 WormBase description: Ser/Thr protein phosphatase
C47B2.6 C47B2.6 P W All gene names: C47B2.6; 1N569; CE17566; CE38295; O62107_CAEEL; WBGene00008132; WP:CE17566; WP:CE38295 WormBase description: The C47B2.6 gene encodes an ortholog of the human gene UDP-GALACTOSE-4-EPIMERASE (GALE; OMIM:606953), which when mutated leads to galactose epimerase deficiency (OMIM:230350). WormBase CDS description: NAD dependant epimerase/dehydratase family
C47C12.5 C47C12.5 P W All gene names: C47C12.5; WBGene00043195
C47E12.11 C47E12.11 P W All gene names: C47E12.11; 4K735; CE05455; WBGene00008154; WP:CE05455
C47E8.5 C47E8.5 P W All gene names: daf-21; tax-3; C47E8.5; C47E8.5.1; C47E8.5.2; C47E8.5.3; 5P167; CE05441; HSP90_CAEEL; NM_074225; WBGene00000915; WP:CE05441 WormBase description: daf-21 encodes a member of the Hsp90 family of molecular chaperones; DAF-21 activity is required for larval development, negative regulation of dauer larva formation, and a number of specific chemosensory behaviors, such as the response to chemicals and odorants detected by the ASE and AWC sensory neurons; a daf-21 sensory defect can be rescued by a cyclic GMP analogue, suggesting that, in regulating chemosensory behaviors, DAF-21 acts at a similar point as the DAF-11 guanylyl cyclase; down-regulation of daf-21 via RNAi results in a small but reproducible reduction in age-1 life span, suggesting that daf-21 is part of a chaperone network required for the extended life span seen in age-1 mutant animals. WormBase CDS description: heat shock protein (HSP90)
C48E7.7 C48E7.7 P W All gene names: C48E7.7; 1G811; CE08822; WBGene00016752; WP:CE08822
C50B6.4 C50B6.4 P W All gene names: col-161; C50B6.4; 5N796; CE08873; NM_073899; WBGene00000734; WP:CE08873 WormBase description: collagen
C52D10.13 C52D10.13 P W All gene names: col-138; C52D10.13; 4S124; CE17596; NM_070647; WBGene00000711; WP:CE17596 WormBase description: cuticular collagen
C52E4.1 C52E4.1 P W All gene names: cpr-1; gcp-1; C52E4.1; 5M457; CE31896; CPR1_CAEEL; CPROT/1; NM_073601; WBGene00000781; WP:CE31896 WormBase description: cpr-1 encodes a cysteine protease of the cathepsin B-like cysteine protease family; cpr-1 appears to be required for embryogenesis; cpr-1 is specifically expressed in the gut of all stages except the embryo and around developing embryos in the gonad; expression of cpr-1 is regulated by three promoter GATA motifs. WormBase CDS description: cathepsin-like cysteine protease
C52E4.7 C52E4.7 P W All gene names: C52E4.7; 5M475; CE08949; WBGene00008259; WP:CE08949
C54D10.7 C54D10.7 P W All gene names: C54D10.7; 5M916; CE05503; WBGene00008301; WP:CE05503
C54D2.1 C54D2.1 P W All gene names: C54D2.1; CE02558; WBGene00016915; WP:CE02558; XI463
C54G4.3 C54G4.3 P W All gene names: C54G4.3; 1I580; CE05509; WBGene00008313; WP:CE05509
C55B7.1 C55B7.1 P W All gene names: glh-2; C55B7.1; 1H93; CE09012; GLH2_CAEEL; NM_059475; WBGene00001599; WP:CE09012 WormBase description: glh-2 encodes a putative DEAD-box RNA helicase that contains six CCHC zinc fingers and is homologous to Drosophila VASA, a germ-line-specific, ATP-dependent, RNA helicase; at non-permissive temperatures, GLH-2 plays a role in germ-line development and fertility, specifically in regulating the normal extent of germ-line proliferation, oogenesis, and the production of functional sperm; GLH-2 activity may also be required for the wild-type morphology of P granules and for localization of several protein components, but not accumulation of P granule mRNA components; GLH-2 interacts in vitro with itself and with KGB-1, a JNK-like MAP kinase; GLH-2 is a constitutive P granule component and thus, with the exception of mature sperm, is expressed in germ cells at all stages of development; GLH-2 is cytoplasmic in oocytes and the early embryo, while perinuclear in all later developmental stages as well as in the distal and medial regions of the hermaphrodite gonad; GLH-2 is expressed at barely detectable levels in males. WormBase CDS description: RNA helicase
C55B7.10 C55B7.10 P W All gene names: C55B7.10; 1H78; CE32839; WBGene00016946; WP:CE32839 WormBase description: casein kinase
C55C3.4 C55C3.4 P W All gene names: C55C3.4; 4G442; CE06991; WBGene00016954; WP:CE06991 WormBase description: tyrosine-protein kinase
MTCE.31 COII P W
D1014.5 D1014.5 P W All gene names: D1014.5; 5I605; CE07007; WBGene00017018; WP:CE07007
D1037.3 D1037.3 P W All gene names: ftn-2; D1037.3; D1037.3.1; D1037.3.2; 1E248; CE20622; NM_058797; Q9TYS3_CAEEL; WBGene00001501; WP:CE20622 WormBase description: ftn-2 encodes one of two C. elegans ferritin heavy chain homologs; loss of ftn-2 activity via deletion mutation results in slightly lower brood sizes and, under iron stress conditions, slightly faster growth from the L4 to adult stage of development, and slightly reduced lifespan; an ftn-2::gfp reporter fusion is expressed in diverse tissues, including the pharynx, intestine, and hypodermis, and its expression, along with that of ftn-2 mRNA, does not appear to change significantly under iron stress conditions. WormBase CDS description: ferritin
D1081.4 D1081.4 P W All gene names: D1081.4; 1J44; CE28544; WBGene00008382; WP:CE28544 WormBase description: guanine nucleotide binding domains
D2023.2 D2023.2 P W All gene names: pyc-1; D2023.2; D2023.2.1; D2023.2.2; D2023.2.3; 5M298; CE09072; NM_073576; PYC1_CAEEL; WBGene00004258; WP:CE09072 WormBase description: pyc-1 encodes the C. elegans pyruvate carboxylase ortholog (OMIM:266150, deficiencies in humans are associated with lactic acidemia, neurological abnormalities, and early death); by homology, PYC-1 is predicted to function as a key regulatory enzyme of gluconeogenesis, lipogenesis, and anaplerosis, localizing to the mitochondrial matrix and catalyzing the formation of oxaloacetate from pyruvate and carbonate; however, loss of pyc-1 activity via large-scale RNAi screens does not result in any obvious abnormalities; pyc-1 expression is induced upon exposure of C. elegans to cadmium. WormBase CDS description: pyruvate carboxylase
D2023.5 D2023.5 P W All gene names: D2023.5; 5M306; CE09075; THT2_CAEEL; WBGene00008409; WP:CE09075 WormBase description: thiosulphate sulphurtransferase
D2030.9 D2030.9 P W All gene names: D2030.9; D2030.9a.1; D2030.9a.2; 1I177; CE09086; CE23620; WBGene00008419; WP:CE09086; WP:CE23620; YRIQ_CAEEL WormBase description: Lithosperm lec14B protein like
E01A2.4 E01A2.F P W
E01G4.6 E01G4.6 P W All gene names: E01G4.6; 2N775; CE15755; WBGene00008448; WP:CE15755
E03H12.5 E03H12.5 P W All gene names: E03H12.5; 4F743; CE09144; WBGene00017112; WP:CE09144
F01F1.6 F01F1.6 P W All gene names: alh-9; F01F1.6; F01F1.6.1; F01F1.6.2; F01F1.6.3; 3G947; AL7A1_CAEEL; CE39486; NM_065862; WBGene00000115; WP:CE39486 WormBase description: Aldehyde dehydrogenase
F02A9.2 F02A9.2 P W All gene names: far-1; F02A9.2; F02A9.2.1; F02A9.2.2; F02A9.2.3; 3K170; CE00133; FAR1_CAEEL; NM_066609; WBGene00001385; WP:CE00133 WormBase description: far-1 encodes a fatty acid/retinol binding protein; expressed throughout development with highest expression levels in L3 stage larvae and in adult males. WormBase CDS description: O. volvulus 20Kd antigenic peptide
F02E9.5 F02E9.5 P W All gene names: F02E9.5; 1J2; CE23628; WBGene00008530; WP:CE23628
F07A5.2 F07A5.2 P W All gene names: F07A5.2; 1H929; CE05555; WBGene00008541; WP:CE05555
F08B1.1 F08B1.1 P W All gene names: nrf-2; vhp-1; F08B1.1; F08B1.1a.1; F08B1.1a.2; F08B1.1a.3; F08B1.1c.1; F08B1.1c.2; F08B1.1c.3; 2F629; CE27918; CE27919; CE32357; NM_062596; NM_062597; NM_182126; VHP1_CAEEL; WBGene00006923; WP:CE27918; WP:CE27919; WP:CE32357 WormBase description: protein tyrosine phosphatase
F08B12.4 F08B12.4 P W All gene names: F08B12.4; F08B12.4.1; F08B12.4.2; CE26708; WBGene00008572; WP:CE26708; XM26; YZ10_CAEEL
F08F3.4 F08F3.4 P W All gene names: F08F3.4; 5F889; CE32856; WBGene00017262; WP:CE32856
C25A6.1 F08F3.5 P W
F08F3.6 F08F3.6 P W All gene names: F08F3.6; 5F896; CE09261; WBGene00017263; WP:CE09261 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
F08G2.1 F08G2.1 P W All gene names: his-44; F08G2.1; 2O118; H2B1_CAEEL; NM_064496; WBGene00001918; his 11 WormBase description: his-44 encodes an H2B histone. WormBase CDS description: Core histones H2A, H2B, H3 and H4
F09B12.1 F09B12.1 P W All gene names: mlt-9; F09B12.1; F09B12.1b.1; F09B12.1b.2; CE23633; CE23634; WBGene00008605; WP:CE23633; WP:CE23634; XP722
F09B9.1 F09B9.1 P W All gene names: F09B9.1; CE15758; WBGene00008602; WP:CE15758; XK758
F09C12.8 F09C12.2 P W
F09C12.7 F09C12.7 P W All gene names: msp-74; msp-74ps; F09C12.7; 2F404; CE02603; NM_062548; WBGene00003462; WP:CE02603 WormBase description: msp-74 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
F09E8.6 F09E8.6 P W All gene names: nas-14; F09E8.6; 4N935; CE35854; NAS14_CAEEL; NM_070132; WBGene00003533; WP:CE35854 WormBase description: zinc metalloprotease
F09F7.5 F09F7.5 P W All gene names: F09F7.5; 3G639; CE01237; CE29259; CE29260; Q19275_CAEEL; WBGene00017302; WP:CE01237; WP:CE29259; WP:CE29260
F09F7.8 F09F7.8 P W All gene names: nspb-12; F09F7.8; 3G656; CE38594; Q19279_CAEEL; WBGene00017305; WP:CE38594 WormBase description: nspb family
F09G2.1 F09G2.1 P W All gene names: F09G2.1; 5H685; CE30744; WBGene00017310; WP:CE30744 WormBase description: tyrosine protein kinase
F10D11.4 F10D11.4 P W All gene names: F10D11.4; 1J16; CE09326; WBGene00008650; WP:CE09326
F10D2.9 F10D2.9 P W All gene names: fat-7; F10D2.9; 5H632; CE09320; NM_072413; WBGene00001399; WP:CE09320 WormBase description: fat-7 encodes an essential delta-9 fatty acid desaturase that is required for the synthesis of monounsaturated fatty acids; fat-7 can substitute for the functions of the other two fatty acid desaturases, fat-5 and fat-6; RNA interference has shown that fat-7 is required for viability and normal growth. WormBase CDS description: stearoyl-CoA desaturase
F10G8.5 F10G8.5 P W All gene names: ncs-2; F10G8.5; 1K610; CE09340; NCS2_CAEEL; NM_060250; WBGene00003564; WP:CE09340 WormBase description: NCS-2 neuronal calcium sensor protein
F11A3.1 F11A3.1 P W All gene names: F11A3.1; F11A3.1.1; F11A3.1.2; 5J989; CE05585; WBGene00008669; WP:CE05585 WormBase description: 4-coumarate-CoA ligase
F11G11.10 F11G11.10 P W All gene names: col-17; F11G11.10; 2F156; CE31783; NM_062477; WBGene00000606; WP:CE31783 WormBase description: col-17 encodes a collagen which is expressed in all developmental stages except eggs, like col-15, col-16, and col-20; collagen genes with this expression pattern may be used for synthesis of cuticles after the L1 stage (e.g., the L4 cuticle). WormBase CDS description: collagen
F11G11.4 F11G11.4 P W All gene names: F11G11.4; 2F151; CE07057; WBGene00017384; WP:CE07057
F11G11.8 F11G11.8 P W All gene names: F11G11.8; 2F150; CE02882; WBGene00017386; WP:CE02882
F11G11.9 F11G11.9 P W All gene names: F11G11.9; 2F152; CE09351; THT1_CAEEL; WBGene00017387; WP:CE09351
F11H8.3 F11H8.3 P W All gene names: col-8; F11H8.3; 3I110; CE04376; COL8_CAEEL; NM_066132; WBGene00000597; WP:CE04376; col8 WormBase description: col-8 encodes a collagen, individually dispensable for viability and gross morphology, which is specifically expressed in dauers and adults but not in eggs or L4 larvae, like col-7, col-18, and col-19; the amino- and carboxyl-terminal cysteine-rich regions of COL-8 are most closely related to those of COL-19, COL-35, and COL-39.
F12B6.2 F12B6.2 P W All gene names: F12B6.2; F12B6.2b.1; F12B6.2b.2; 1C821; CE30273; CE30512; CE30513; CE39012; WBGene00017398; WP:CE30273; WP:CE30512; WP:CE30513; WP:CE39012 WormBase description: sodium dependent-phosphate transporter
F13D2.1 F13D2.1 P W All gene names: F13D2.1; CE37347; WBGene00008735; WP:CE37347; XL784 WormBase description: alpha-1-macroglobulin-like domain
F13G3.5 F13G3.5 P W All gene names: F13G3.5; F13G3.5.1; F13G3.5.2; 1H878; CE29761; IMPA1_CAEEL; WBGene00008765; WP:CE29761 WormBase description: myo-inositol-1-monophosphatase
F14D7.7 F14D7.7 P W All gene names: F14D7.7; 5O788; CE09385; WBGene00008794; WP:CE09385
F14F7.1 F14F7.1 P W All gene names: col-98; F14F7.1; F14F7.1.1; F14F7.1.2; 3O109; CE15821; NM_067302; WBGene00000673; WP:CE15821 WormBase description: collagen
F14H8.1 F14H8.1 P W All gene names: obr-2; F14H8.1; 5P492; CE35859; NM_074294; WBGene00008832; WP:CE35859 WormBase description: oxysterol-binding protein
F15B9.1 F15B9.1 P W All gene names: far-3; F15B9.1; 5N476; CE09406; NM_073850; WBGene00001387; WP:CE09406 WormBase description: O.volvulus antigen peptide like
F15H10.1 F15H10.1 P W All gene names: col-12; F15H10.1; F15H10.1.1; F15H10.1.2; 5K904; CE05638; COL12_CAEEL; NM_073277; WBGene00000601; WP:CE05638 WormBase description: col-12 encodes a member of the collagen superfamily containing collagen triple helix repeats (20 copies); expressed throughout development but expression peaks after each larval molt when new cuticle is being secreted and deposited, and after the L4 to adult larval molt. WormBase CDS description: collagen
F17C8.3 F17C8.3 P W All gene names: F17C8.3; 3F825; CE35179; WBGene00008910; WP:CE35179
F17E9.5 F17E9.5 P W All gene names: F17E9.5; 4J111; CE07072; O61521_CAEEL; WBGene00017542; WP:CE07072
F19B10.9 F19B10.9 P W All gene names: sea-1; tbx-18; F19B10.9; CE09476; TBX18_CAEEL; WBGene00004750; WP:CE09476
F19B2.5 F19B2.5 P W All gene names: F19B2.5; F19B2.C; 5U632; CE20697; WBGene00008944; WP:CE20697
F19H6.4 F19H6.4 P W All gene names: F19H6.4; CE03235; WBGene00008959; WP:CE03235; XM985 WormBase description: 3-oxo-5-alpha-steroid 4-dehydrogenase
F20D6.6 F20D6.6 P W All gene names: F20D6.6; 5I641; CE07111; WBGene00017636; WP:CE07111 WormBase description: serine/threoninie protein phophatase
F21C10.7 F21C10.7 P W All gene names: F21C10.7; 5J601; CE07122; WBGene00017657; WP:CE07122
F21C3.5 F21C3.5 P W All gene names: F21C3.5; 1H860; CE05680; PFD6_CAEEL; WBGene00009004; WP:CE05680 WormBase description: Mouse KE2 protein like
F21F8.4 F21F8.4 P W All gene names: F21F8.4; F21F8.4.1; F21F8.4.2; 5I751; CE09540; WBGene00017678; WP:CE09540 WormBase description: protease
F21H12.5 F21H12.5 P W All gene names: fbf-2; F21H12.5; 2G380; CE01916; FBF2_CAEEL; NM_062819; WBGene00001402; WP:CE01916 WormBase description: fbf-2 encodes an RNA-binding protein that is one of 11 C. elegans members of the PUF family (Pumilio and FBF) of translational regulators; FBF-2 is nearly identical to FBF-1 with which it is largely redundant in regulating two aspects of germline development: 1)maintenance of stem cell proliferation, and 2)the hermaphroditic switch between spermatogenesis and oogenesis; in maintaining germline stem cells, the FBF proteins, acting through NOS-3, negatively regulate the activity of gld-1 mRNA, which encodes a translational repressor required for meiotic entry; in regulating the sperm-to-oocyte switch, the FBFs act downstream of GLD-3 to negatively regulate the activity of fem-3 mRNA, which encodes a novel protein required for germline sex determination; consistent with their role in germline development, FBF-1 and FBF-2 are expressed in the germline cytoplasm, becoming enriched in the mitotic region during the L4 larval and adult stages.
F21H7.2 F21H7.2 P W All gene names: F21H7.2; F21H7.2.1; F21H7.2.2; 5Q708; CE15875; WBGene00009028; WP:CE15875
F21H7.5 F21H7.5 P W All gene names: F21H7.5; 5Q719; CE15877; WBGene00009031; WP:CE15877
F22A3.1 F22A3.1 P W All gene names: ets-4; F22A3.1; CE34001; WBGene00017687; WP:CE34001; XH139 WormBase description: DNA binding protein, ETS domain
F22G12.5 F22G12.5 P W All gene names: F22G12.5; 1N773; CE15892; WBGene00009065; WP:CE15892
F23B12.1 F23B12.1 P W All gene names: F23B12.1; 5O909; CE09593; WBGene00009079; WP:CE09593 WormBase description: serine/threonine protein phosphatase
F25D1.5 F25D1.5 P W All gene names: F25D1.5; 5L26; CE05726; Q19774_CAEEL; WBGene00009110; WP:CE05726 WormBase description: dehydrogenase
F25E5.8 F25E5.8 P W All gene names: F25E5.8; F25E5.8a.1; F25E5.8a.2; F25E5.8b.1; F25E5.8b.2; 5H917; CE07142; CE32876; WBGene00017789; WP:CE07142; WP:CE32876
F26A1.4 F26A1.4 P W All gene names: F26A1.4; 3F903; CE02685; WBGene00017803; WP:CE02685 WormBase description: Casein kinase
F26A3.5 F26A3.5 P W All gene names: F26A3.5; 1I245; CE09670; WBGene00009143; WP:CE09670
F26F4.2 F26F4.2 P W All gene names: F26F4.2; 3G1; CE29288; Q19823_CAEEL; WBGene00005012; WP:CE29288 WormBase description: spt-2 encodes a novel protein with high similarity to C. elegans F37A8.1 and C. briggsae CBG18186.
F26G1.5 F26G1.5 P W All gene names: F26G1.5; 2F60; CE02697; WBGene00017841; WP:CE02697
F26G1.7 F26G1.7 P W All gene names: msp-3; F26G1.7; 2F76; CE02699; MSP3_CAEEL; NM_062457; WBGene00003424; WP:CE02699 WormBase description: msp-3 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-3 is similar in nucleotide sequence to the msp genes from the nematode Onchocerca volvulus; the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP proteins assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. WormBase CDS description: Major sperm protein
F27B3.5 F27B3.1 P W
F27C1.1 F27C1.1 P W All gene names: F27C1.1; 1G3; CE09714; WBGene00017851; WP:CE09714
F27C8.4 F27C8.4 P W All gene names: spp-18; F27C8.4; 4K359; CE03269; NM_069303; WBGene00005003; WP:CE03269
F27D4.4 F27D4.4 P W All gene names: F27D4.4; 1I303; CE36141; WBGene00009189; WP:CE36141 WormBase description: Yeast hypothetical protein YOR316OW like
F28D1.5 F28D1.5 P W All gene names: thn-2; F28D1.5; 4N149; CE05745; NM_069961; WBGene00009215; WP:CE05745 WormBase description: Arabidopsis pathogenesis-related protein 5 like
F28E10.4 F28E10.4 P W All gene names: F28E10.4; 4F332; CE04461; WBGene00017902; WP:CE04461
F28F5.3 F28F5.2 P W
F28F5.4 F28F5.4 P W All gene names: F28F5.4; CE00791; WBGene00043297; WP:CE00791
F29D10.2 F29D10.2 P W All gene names: F29D10.2; 1J419; CE38335; WBGene00009251; WP:CE38335
F29G9.1 F29G9.1 P W All gene names: F29G9.1; 5G519; CE35297; WBGene00017930; WP:CE35297
F31E8.5 F31E8.5 P W All gene names: F31E8.5; 2H94; CE35516; WBGene00017955; WP:CE35516
F32A11.3 F32A11.3 P W All gene names: F32A11.3; 2N442; CE17739; WBGene00009308; WP:CE17739
F32B4.2 F32B4.2 P W All gene names: F32B4.2; 1M104; CE36146; WBGene00009313; WP:CE36146
F32B5.1 F32B5.1 P W All gene names: F32B5.1; 1D269; CE28230; WBGene00017975; WP:CE28230 WormBase description: phosphotransferase
F32B6.5 F32B6.5 P W All gene names: sss-1; F32B6.5; 4K658; CE09860; NM_069379; Q9XVP7_CAEEL; WBGene00006056; WP:CE09860
F32B6.6 F32B6.6 P W All gene names: msp-77; F32B6.6; 4K659; CE09861; NM_069380; WBGene00003464; WP:CE09861 WormBase description: msp-77 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. WormBase CDS description: major sperm protein
F32D1.5 F32D1.5 P W All gene names: F32D1.5; F32D1.5.1; F32D1.5.2; 5E848; CE09869; GMPR_CAEEL; WBGene00017984; WP:CE09869 WormBase description: GMP reductase
F32G8.6 F32G8.6 P W All gene names: cat-4; F32G8.6; 5L45; CE05795; GCH1_CAEEL; NM_073309; WBGene00000298; WP:CE05795 WormBase description: cat-4 encodes an ortholog of the human GTP cyclohydrolase I gene (GCH1; OMIM:600225), which when mutated leads to dystonia; CAT-4 is involved in serotonin and dopamine biosynthesis that affects movement, mating behavior, foraging behavior, and cell migration; CAT-4 acts in the same genetic pathway as flp-1. WormBase CDS description: GTP cyclohydrolase I
F32H5.1 F32H5.1 P W All gene names: F32H5.1; 5N836; CE09885; WBGene00009347; WP:CE09885 WormBase description: cathepsin B like cysteine protease
F33D11.2 F33D11.2 P W All gene names: F33D11.2; 1G425; CE09892; WBGene00018001; WP:CE09892
F33D11.7 F33D11.7 P W All gene names: F33D11.7; 1G426; CE09897; WBGene00018004; WP:CE09897 WormBase description: protein kinase
F33D4.1 F33D4.1 P W All gene names: nhr-8; F33D4.1; 4I477; CE33927; CE33928; NHR8_CAEEL; NM_171382; WBGene00003607; WP:CE33927; WP:CE33928 WormBase description: The nhr-8 gene encodes a nuclear hormone receptor homolog; nhr-8(ok186) mutants have abnormally low resistance to the toxins colchicine and chloroquine.
F33H1.4 F33H1.4 P W All gene names: F33H1.4; 2K469; CE02206; WBGene00009365; WP:CE02206
F34D10.2 F34D10.2 P W All gene names: F34D10.2; F34D10.2.1; F34D10.2.2; 3E820; CE01570; WBGene00009372; WP:CE01570
F34D6.4 F34D6.4 P W All gene names: F34D6.4; 2C980; CE36838; WBGene00018023; WP:CE36838
F35B12.3 F35B12.3 P W All gene names: F35B12.3; CE31929; NM_073541; WBGene00009383; WP:CE31929
F35C11.2 F35C11.2 P W All gene names: F35C11.2; 2I534; CE02209; WBGene00009401; WP:CE02209 WormBase description: protein-tyrosine phosphatase
F35C11.3 F35C11.3 P W All gene names: F35C11.3; 2I537; CE02210; WBGene00009402; WP:CE02210 WormBase description: serine/threonine kinase
F35C5.5 F35C5.5 P W All gene names: clec-62; F35C5.5; 2N184; CE15945; CE15946; WBGene00009393; WP:CE15945; WP:CE15946 WormBase description: Lectin C-type domain short and long forms, von Willebrand factor type A domain
F35C8.6 F35C8.6 P W All gene names: pfn-2; F35C8.6; CE39098; NM_076509; PROF2_CAEEL; WBGene00003990; WP:CE39098; XF972
F36A2.11 F36A2.11 P W All gene names: F36A2.11; 1J399; CE34181; WBGene00009458; WP:CE34181
F36A2.14 F36A2.12 P W
F36A4.10 F36A4.10 P W All gene names: alpha-collagen; col-34; ram-4; F36A4.10; 4F8; CE07185; COL34_CAEEL; NM_068119; WBGene00000611; WP:CE07185 WormBase description: col-34 encodes a cuticle collagen protein and is a critical component of male tail cuticle organization affecting ray morphology. WormBase CDS description: cuticular collagen
F36A4.4 F36A4.4 P W All gene names: F36A4.4; 4F33; CE07180; WBGene00018083; WP:CE07180
F36A4.6 F36A4.6 P W All gene names: col-33; F36A4.6; 4F29; CE34548; NM_068123; WBGene00000610; WP:CE34548 WormBase description: col-33 encodes a predicted cuticular collagen; by homology, col-33 is predicted to play a role in cuticle biosynthesis and regulation of body size and morphogenesis; however, as loss of col-33 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of COL-33 in C. elegans development and/or behavior is not yet known. WormBase CDS description: cuticular collagen
F36G3.2 F36G3.2 P W All gene names: F36G3.2; CE01577; WBGene00009483; WP:CE01577; XK412; YQY2_CAEEL
F36H12.10 F36H12.10 P W All gene names: F36H12.10; 4G18; CE09981; WBGene00018124; WP:CE09981
F36H12.3 F36H12.3 P W All gene names: F36H12.3; 4G39; CE09975; WBGene00018119; WP:CE09975
F36H12.7 F36H12.7 P W All gene names: msp-19; F36H12.7; 4G25; CE02806; NM_068359; WBGene00003426; WP:CE02806 WormBase description: msp-19 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-19 has a homolog in C. briggsae as predicted by the Wobble Aware Bulk Aligner (WABA); the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. WormBase CDS description: major sperm protein MSP-19
F36H12.8 F36H12.8 P W All gene names: F36H12.8; 4G23; CE09979; WBGene00018122; WP:CE09979
F36H12.9 F36H12.9 P W All gene names: F36H12.9; 4G21; CE09980; WBGene00018123; WP:CE09980
F38A3.2 F38A3.2 P W All gene names: col-82; ram-2; ram-3; F38A3.2; 2L306; CE02214; NM_063961; WBGene00004300; WP:CE02214 WormBase description: ram-2 encodes a cuticle collagen that interacts with unc-6 to affect ray cell migration, and interacts with unc-5 and unc-6 to affect embryonic viability; also affects ray morphology in males such that the structural cells and the hypodermis of the rays are swollen in mutants. WormBase CDS description: collagen
F38H4.6 F38H4.6 P W All gene names: F38H4.6; 4M612; CE10068; WBGene00009550; WP:CE10068
F40E10.5 F40E10.5 P W All gene names: F40E10.5; CE05840; NM_078040; WBGene00009573; WP:CE05840; XP321
F40F4.6 F40F4.6 P W All gene names: F40F4.6; CE04536; WBGene00018237; WP:CE04536; XD856 WormBase description: EGF-like repeats
F40F8.7 F40F8.7 P W All gene names: pqm-1; pqm-132; F40F8.7; 2L442; CE05846; CePqM132; NM_063990; WBGene00004096; WP:CE05846 WormBase description: pqm-1 encodes a C2H2-type zinc finger and leucine zipper-containing protein that is upregulated in response to oxidative stress induced by paraquat treatment; PQM-1 may function as a stress-responsive transcription factor. WormBase CDS description: Zinc finger, C2H2 type
F40F9.2 F40F9.2 P W All gene names: tag-120; F40F9.2; 5K188; CE05851; WBGene00006470; WP:CE05851 WormBase description: tag-120 encodes a predicted transmembrane protein; as loss of tag-120 activity via RNAi does not result in any abnormalities, the precise role of TAG-120 in C. elegans development and/or behavior is not yet known; however, TAG-120 is homologous to a Drosophila NMDA receptor-associated protein and mammalian transmembrane proteins that function in Fas-mediated cell death, so TAG-120 may play a role in neuronal functions and/or apoptosis; a tag-120 reporter fusion is expressed in the nervous system, pharyngeal muscles, and to a lesser extent in the excretory system. WormBase CDS description: N-methyl-D-aspartate receptor associated protein
F40F9.3 F40F9.3 P W All gene names: F40F9.3; 5K195; CE05852; WBGene00009581; WP:CE05852 WormBase description: PDZ domain (Also known as DHR or GLGF).
F40G12.10 F40G12.10 P W All gene names: F40G12.10; 5O765; CE10194; WBGene00009605; WP:CE10194 WormBase description: protein-tyrosine phosphatase
F41E6.11 F41E6.11 P W All gene names: F41E6.11; 5J100; CE10264; WBGene00018292; WP:CE10264
F42A10.7 F42A10.7 P W All gene names: F42A10.7; F42A10.7.1; F42A10.7.2; 3H268; CE01298; WBGene00018343; WP:CE01298
F42E8.2 F42E8.2 P W All gene names: F42E8.2; 5N544; CE10304; WBGene00009631; WP:CE10304
F42G8.3 F42G8.3 P W All gene names: pmk-2; F42G8.3; 4I911; CE31695; CE34862; NM_171392; NM_171913; PMK2_CAEEL; WBGene00004056; WP:CE31695; WP:CE34862 WormBase description: The pmk-2 gene encodes a homolog of p38, a type of mitogen-activated protein kinase (MAPK) that in mammals is generally activated by diverse cellular stresses and ligands.
F42G9.1 F42G9.1 P W All gene names: F42G9.1; 3B403; CE07231; CE30788; PP2C1_CAEEL; WBGene00018362; WP:CE07231; WP:CE30788 WormBase description: Protein phosphatase
F42H11.1 F42H11.1 P W All gene names: F42H11.1; 1K153; CE10330; WBGene00009646; WP:CE10330
F42H11.2 F42H11.2 P W All gene names: lem-3; F42H11.2; F42H11.2.1; F42H11.2.2; 1K156; CE10332; NM_060138; WBGene00002276; WP:CE10332 WormBase description: ankyrin domain
F43G9.10 F43G9.10 P W All gene names: F43G9.10; 1J216; CE10372; WBGene00009671; WP:CE10372 WormBase description: MICROFIBRILLAR-ASSOCIATED PROTEIN 1 (ASSOCIATED MICROFIBRIL PROTEIN) (AMF)
F43H9.2 F43H9.2 P W All gene names: sptl-2; F43H9.2; 5I501; CE07246; CE27380; WBGene00018398; WP:CE07246; WP:CE27380 WormBase description: serine palmtoyltransferase
F44B9.8 F44B9.8 P W All gene names: F44B9.8; 3J118; CE37518; RFC5_CAEEL; WBGene00018409; WP:CE37518 WormBase description: ARPA
F44C4.3 F44C4.3 P W All gene names: cpr-4; F44C4.3; F44C4.3.1; F44C4.3.2; 5H95; CE07251; CPR4_CAEEL; NM_072281; WBGene00000784; WP:CE07251 WormBase description: cpr-4 encodes a cathepsin B-like cysteine protease expressed at all life stages. WormBase CDS description: cathepsin B-like cysteine proteinase 4 precursor
F44D12.7 F44D12.7 P W All gene names: F44D12.7; 4K799; WBGene00009684
F44F4.10 F44F4.10 P W All gene names: F44F4.10; 2L206; CE00997; WBGene00009705; WP:CE00997
F45C12.7 F45C12.7 P W All gene names: F45C12.7; 2C5; CE10448; WBGene00018438; WP:CE10448
F45D3.4 F45D3.4 P W All gene names: F45D3.4; 5N32; CE10474; CE38518; WBGene00009724; WP:CE10474; WP:CE38518
F45E4.1 F45E4.1 P W All gene names: arf-1.1; arl-6; F45E4.1; 4I401; ARF11_CAEEL; CE10492; NM_068841; WBGene00000190; WP:CE10492 WormBase description: arf-1.1 encodes a member of the ADP-ribosylation factor family. WormBase CDS description: ADP-ribosylation factor
F45E6.5 F45E6.5 P W All gene names: F45E6.5; WBGene00043329
F46B6.7 F46B6.7 P W All gene names: ztf-7; F46B6.7; F46B6.7.1; F46B6.7.2; 5K268; CE05873; WBGene00009772; WP:CE05873 WormBase description: Zinc finger, C2H2 type
F46C8.1 F46C8.1 P W All gene names: F46C8.1; CE04576; WBGene00018484; WP:CE04576; XI169
F46C8.6 F46C8.6 P W All gene names: dpy-7; F46C8.6; F46C8.6.1; F46C8.6.2; CE04580; DPY7_CAEEL; NM_076873; WBGene00001069; WP:CE04580; XI156 WormBase description: dpy-7 encodes a cuticular collagen; DPY-7 functions as a structural constituent of the extracellular cuticle whose activity is required for normal cuticular morphology and hence, proper body form. WormBase CDS description: cuticle collagen
F46G10.5 F46G10.5 P W All gene names: ptr-24; F46G10.5; CE31522; NM_077821; WBGene00004238; WP:CE31522; XN965 WormBase description: ptr-24 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-24 has no known function in vivo.
F46G10.6 F46G10.6 P W All gene names: hlh-23; mxl-3; F46G10.6; CE05882; NM_077822; WBGene00003511; WP:CE05882; XN968 WormBase description: Helix-loop-helix DNA-binding domain
F47B3.1 F47B3.1 P W All gene names: F47B3.1; 1E541; CE10616; WBGene00018525; WP:CE10616 WormBase description: protein-tyrosine phosphatase
F47B3.4 F47B3.4 P W All gene names: F47B3.4; 1E529; CE10622; WBGene00018528; WP:CE10622
F47B3.5 F47B3.5 P W All gene names: F47B3.5; 1E530; CE10624; WBGene00018529; WP:CE10624
F47B3.6 F47B3.6 P W All gene names: F47B3.6; 1E534; CE36648; WBGene00018530; WP:CE36648
F47B3.7 F47B3.7 P W All gene names: F47B3.7; 1E536; CE10628; WBGene00018531; WP:CE10628
F47B8.11 F47B8.11 P W All gene names: sss-2; F47B8.11; 5O827; CE10652; NM_074156; WBGene00006057; WP:CE10652
F47C12.4 F47C12.4 P W All gene names: clec-79; F47C12.4; 4E739; CE10676; WBGene00018548; WP:CE10676
F47G4.7 F47G4.7 P W All gene names: smd-1; F47G4.7; F47G4.7.1; F47G4.7.2; 1O640; CE18705; DCAM_CAEEL; NM_061047; WBGene00004875; WP:CE18705; samdc
F48C1.7 F48C1.7 P W All gene names: spe-11; F48C1.7; 1F900; CE10744; NM_059168; SPE11_CAEEL; WBGene00004965; WP:CE10744 WormBase description: spe-11 encodes a novel protein that is required for early embryonic development and for regulating the dynamic morphology of sperm pseudopods; although the precise biological role of SPE-11 is not yet known, SPE-11 is one of the few paternally provided proteins known to be essential for embryogenesis, and may constitute a sperm-associated factor required for oocyte activation; SPE-11 is first detected in the nuclei of primary spermatocytes and then remains tightly associated with sperm chromatin until fertilization at which point it appears to be degraded.
F49C12.15 F49C12.15 P W All gene names: F49C12.15; 4K91; CE03375; WBGene00009884; WP:CE03375
F52B10.1 F52B10.1 P W All gene names: nmy-1; F52B10.1; CE31177; NM_076103; Q20641_CAEEL; WBGene00003776; WP:CE31177; XD535 WormBase description: nmy-1 encodes a class II non-muscle myosin heavy chain related to Drosophila zipper, which plays a role in several aspects of embryonic morphogenesis; in C. elegans, NMY-1 is required for embryonic elongation and establishment of normal body morphology; however, nmy-1 functions redundantly with another non-muscle myosin heavy chain gene, nmy-2, during elongation and establishment of normal body morphology; mutations in nmy-1 suppress the hypercontraction phenotype produced by mutations in mel-11, a myosin phosphatase that regulates actomyosin filament contraction; in addition, NMY-1 may partner with MLC-4, myosin light chain 4, during elongation; NMY-1 expression is detected during embryogenesis, particularly at the onset of elongation. WormBase CDS description: myosin
F52E1.14 F52E1.5 P W
F52F12.5 F52F12.5 P W All gene names: F52F12.5; 1K496; CE10848; WBGene00009938; WP:CE10848
F53A9.6 F53A9.6 P W All gene names: F53A9.6; F53A9.6.1; F53A9.6.2; CE02766; WBGene00018729; WP:CE02766; XJ332
F53B3.5 F53B3.4 P W
F53F10.3 F53F10.3 P W All gene names: F53F10.3; F53F10.3.1; F53F10.3.2; 1E395; CE28447; WBGene00018765; WP:CE28447; YXX3_CAEEL
F53G12.8 F53G12.8 P W All gene names: F53G12.8; 1A587; CE36697; WBGene00018773; WP:CE36697
F54C1.8 F54C1.8 P W All gene names: F54C1.8; 1F574; CE34315; WBGene00018792; WP:CE34315
F54C9.9 F54C9.9 P W All gene names: F54C9.9; 2I871; CE20865; WBGene00010044; WP:CE20865
F54D1.1 F54D1.1 P W All gene names: F54D1.1; 4M25; CE05936; WBGene00010046; WP:CE05936
F54D5.3 F54D5.3 P W All gene names: F54D5.3; F54D5.3.1; F54D5.3.2; 2L863; CE28033; WBGene00010049; WP:CE28033
F54D5.9 F54D5.9 P W All gene names: F54D5.9; 2L834; CE03413; WBGene00010053; WP:CE03413 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
F54D8.6 F54D8.6 P W All gene names: F54D8.6; 3G195; CE31000; Q8MQ25_CAEEL; WBGene00018802; WP:CE31000
F54F7.3 F54F7.3 P W All gene names: F54F7.3; CE03418; WBGene00010065; WP:CE03418; XM468
F55C10.2 F55C10.2 P W All gene names: col-154; F55C10.2; 5L865; CE05952; NM_073485; WBGene00000727; WP:CE05952 WormBase description: collagen
F55C10.3 F55C10.3 P W All gene names: col-155; F55C10.3; 5L868; CE11182; CO155_CAEEL; NM_073487; WBGene00000728; WP:CE11182 WormBase description: collagen
F55C12.1 F55C12.1 P W All gene names: F55C12.1; F55C12.1a.1; F55C12.1a.2; F55C12.1d.1; F55C12.1d.2; 2G181; CE02770; CE28452; CE31958; CE31959; Q95ZS6_CAEEL; WBGene00018869; WP:CE02770; WP:CE28452; WP:CE31958; WP:CE31959
F55C12.3 F55C12.3 P W
F55D10.2 F55D10.2 P W All gene names: rpl-25.1; F55D10.2; F55D10.2.1; F55D10.2.2; CE02777; NM_076407; R23A1_CAEEL; WBGene00004438; WP:CE02777; XF335 WormBase description: rpl-25.1 encodes a large ribosomal subunit L23a protein. WormBase CDS description: Ribosomal protein L23
F55D12.6 F55D12.6 P W All gene names: F55D12.6; 1I479; CE17876; WBGene00010114; WP:CE17876
F55F8.7 F55F8.7 P W All gene names: F55F8.7; 1G228; CE11200; WBGene00018895; WP:CE11200 WormBase description: protein-tyrosine phosphatase
F56B3.1 F56B3.1 P W All gene names: col-103; F56B3.1; 4B516; CE17882; NM_067581; WBGene00000677; WP:CE17882
F56D6.2 F56D6.2 P W All gene names: clec-67; F56D6.2; 4E687; CE31546; WBGene00018971; WP:CE31546
F56F10.1 F56F10.1 P W All gene names: F56F10.1; F56F10.1.1; F56F10.1.2; CE34034; WBGene00018984; WP:CE34034; XB493; YM9I_CAEEL WormBase description: peptidase
F56F3.4 F56F3.4 P W All gene names: F56F3.4; 3F561; CE01016; WBGene00010155; WP:CE01016 WormBase description: Ubiquitin family
F57B7.3 F57B7.3 P W All gene names: col-156; F57B7.3; 5L930; CE05991; NM_073501; WBGene00000729; WP:CE05991 WormBase description: collagen
F57B9.6 F57B9.6 P W All gene names: inf-1; F57B9.6; F57B9.6a.1; F57B9.6a.2; 3I21; CE01341; CE38524; Ce1F; CeIF; IF4A_CAEEL; NM_066108; WBGene00002083; WP:CE01341; WP:CE38524 WormBase description: inf-1 encodes a protein with high similarity to eukaryotic initiation factor 4A.
F57F4.3 F57F4.3 P W All gene names: gfi-1; F57F4.3; 5G882; CE11342; NM_072225; WBGene00001581; WP:CE11342 WormBase description: gfi-1 encodes a protein that contains 21 ET modules; interacts with unc-68 in yeast two-hybrid assays.
F57F4.4 F57F4.4 P W All gene names: F57F4.4; F57F4.4.1; F57F4.4.2; F57F4.4.3; CE11344; NM_072226; WBGene00019017; WP:CE11344
F58A6.11 F58A6.11 P W All gene names: srb-13; F58A6.11; 2F446a; CE07297; NM_062557; WBGene00019028; WP:CE07297 WormBase description: 7TM chemoreceptor, srb family
F58A6.8 F58A6.8 P W All gene names: msp-45; F58A6.8; 2F446; NM_062558; WBGene00003438 WormBase description: msp-45 encodes a member of the major sperm protein family. WormBase CDS description: major sperm protein
F58A6.9 F58A6.9 P W All gene names: F58A6.9; 2F448; WBGene00019026 WormBase description: major sperm protein
F58B3.1 F58B3.1 P W All gene names: lys-4; F58B3.1; 4M386; CE06003; NM_069791; WBGene00003093; WP:CE06003
F58D2.2 F58D2.2 P W All gene names: F58D2.2; 4N955; CE11364; WBGene00010241; WP:CE11364
F58E6.5 F58E6.5 P W All gene names: F58E6.5; 5K234; CE06020; WBGene00010254; WP:CE06020
F58E6.7 F58E6.7 P W All gene names: F58E6.7; 5K237; CE38525; WBGene00010256; WP:CE38525
F58F6.1 F58F6.1 P W All gene names: col-104; F58F6.1; 4C118; CE17136; NM_067669; WBGene00000678; WP:CE17136 WormBase description: cuticular collagen
F58G1.3 F58G1.3 P W All gene names: F58G1.3; 2N218; CE35562; O62272_CAEEL; WBGene00010265; WP:CE35562 WormBase description: Protein phosphatase-1 (PP1) (2 domains)
F58H7.8 F58H7.8 P W All gene names: F58H7.8; 4B663; CE17936; WBGene00019073; WP:CE17936
F59A1.10 F59A1.10 P W All gene names: F59A1.10; 5S141; CE18794; WBGene00010296; WP:CE18794
F59A2.3 F59A2.3 P W All gene names: F59A2.3; F59A2.3.1; F59A2.3.2; 3E487; CE17940; WBGene00010303; WP:CE17940; YMI3_CAEEL WormBase description: Splicing factor-associated 32K chain
F59D8.B F59D8.B P W
F59D8.1 F59D8.F P W
F59E12.1 F59E12.1 P W All gene names: F59E12.1; 2F947; CE28569; WBGene00019118; WP:CE28569
F59E12.12 F59E12.12 P W All gene names: bli-2; F59E12.12; 2F940; CE11540; NM_062703; WBGene00000252; WP:CE11540 WormBase description: A cuticle collagen involved in strut assembly in the adult cuticle.
H03E18.1 H03E18.1 P W All gene names: H03E18.1; CE37653; WBGene00019148; WP:CE37653; XJ131
H06I04.3 H06I04.H P W
H15N14.2 H15N14.1 P W
H17B01.2 H17B01.2 P W All gene names: col-70; H17B01.2; 2B759; CE11592; NM_061577; WBGene00000646; WP:CE11592 WormBase description: collagen
K01C8.1 K01C8.1 P W All gene names: K01C8.1; K01C8.1.1; K01C8.1.2; K01C8.1.3; 2I557; CE36943; WBGene00010456; WP:CE36943 WormBase description: threonine dehydratase
K01D12.11 K01D12.11 P W All gene names: cdr-4; K01D12.11; 5M886; CE06050; NM_073709; WBGene00010470; WP:CE06050 WormBase description: glutathione S-transferase
K01D12.15 K01D12.15 P W All gene names: K01D12.15; 5M867; CE28043; WBGene00010474; WP:CE28043
K01D12.7 K01D12.7 P W All gene names: K01D12.7; 5M882; CE28483; WBGene00010466; WP:CE28483
K01D12.8 K01D12.8 P W All gene names: K01D12.8; 5M883; CE34199; WBGene00010467; WP:CE34199
K01G5.3 K01G5.3 P W All gene names: K01G5.3; 3L841; CE16193; WBGene00010477; WP:CE16193
K01G5.4 K01G5.4 P W All gene names: ran-1; K01G5.4; K01G5.4.1; K01G5.4.2; K01G5.4.3; 3L836; CE16194; NM_066968; RAN_CAEEL; WBGene00004302; WP:CE16194 WormBase description: GTP-binding protein
K02D7.3 K02D7.3 P W All gene names: col-101; K02D7.3; 4B78; CE17996; NM_067504; WBGene00000675; WP:CE17996 WormBase description: cuticular collagen
K02E2.6 K02E2.6 P W All gene names: K02E2.6; K02E2.6.1; K02E2.6.2; 5U851; CE23845; WBGene00010507; WP:CE23845
K02F3.4 K02F3.4 P W All gene names: zip-2; K02F3.4; K02F3.4.1; K02F3.4.2; 3B453; CE23848; WBGene00019327; WP:CE23848
K03B8.8 K03B8.8 P W All gene names: K03B8.8; 5L886; CE06082; WBGene00010525; WP:CE06082
K03H1.10 K03H1.10 P W All gene names: K03H1.10; K03H1.10.1; K03H1.10.2; 3L15; CE00571; WBGene00010545; WP:CE00571
K04F1.1 K04F1.1 P W All gene names: K04F1.1; 5C132; CE36877; WBGene00019384; WP:CE36877
K04H4.1 K04H4.1 P W All gene names: clb-2; emb-9; zyg-6; K04H4.1; 3K428; CE36389; CE36390; CO4A1_CAEEL; WBGene00001263; WP:CE36389; WP:CE36390 WormBase description: emb-9 encodes the alpha-1 chain of Type IV basement membrane collagen most closely equivalent to human COL4A1 (OMIM:120130) on the basis of biological function; EMB-9 forms heterotrimeric Type IV collagen with LET-2, the alpha-2-like chain, and is required for the assembly and/or secretion of LET-2; EMB-9 is essential for embryonic morphogenesis, particularly epidermal elongation, and for larval development; EMB-9 is expresed primarily by body wall muscles and some somatic cells of the gonad and is detected in nearly all basement membranes. WormBase CDS description: collagen
K05C4.1 K05C4.1 P W All gene names: pbs-5; K05C4.1; K05C4.1.1; K05C4.1.2; 1P310; CE19969; NM_061157; WBGene00003951; WP:CE19969 WormBase description: Proteasome A-type and B-type
K05F1.2 K05F1.2 P W All gene names: msp-142; K05F1.2; 2G89; MSP19_CAEEL; NM_062743; WBGene00003469 WormBase description: msp-142 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. WormBase CDS description: Major sperm protein (msp-142)
K05F1.3 K05F1.3 P W All gene names: K05F1.3; 2G85; CE02807; WBGene00019406; WP:CE02807 WormBase description: Acyl-coA dehydrogenase
K05F1.7 K05F1.7 P W All gene names: msp-63; K05F1.7; 2G86; CE02811; MSP63_CAEEL; NM_062742; WBGene00003456; WP:CE02811 WormBase description: msp-63 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. WormBase CDS description: Major sperm protein
K05F1.9 K05F1.9 P W All gene names: K05F1.9; 2G90; CE02813; WBGene00019410; WP:CE02813
K05G3.3 K05G3.3 P W All gene names: cah-3; K05G3.3; CAH3_CAEEL; CE04755; NM_078273; WBGene00000281; WP:CE04755; XR103 WormBase description: carbonic anhydrase 2. WormBase CDS description: carbonic anhydrase
K06H7.8 K06H7.8 P W All gene names: K06H7.8; 3J186; CE25045; WBGene00019459; WP:CE25045; YMX8_CAEEL
K07A1.10 K07A1.10 P W All gene names: K07A1.10; 1K190; CE39387; WBGene00010616; WP:CE39387
K07A1.4 K07A1.4 P W All gene names: K07A1.4; 1K166; CE11846; WBGene00010611; WP:CE11846
K07A1.5 K07A1.5 P W All gene names: K07A1.5; 1K167; CE11848; WBGene00010612; WP:CE11848
K07E3.1 K07E3.1 P W All gene names: K07E3.1; CE39593; WBGene00019490; WP:CE39593; XI733
K07F5.1 K07F5.1 P W All gene names: msp-81; K07F5.1; 4K600; NM_069358; WBGene00003467 WormBase description: msp-81 encodes a member of the major sperm protein family. WormBase CDS description: major sperm protein
K07F5.11 K07F5.11 P W All gene names: ssq-1; K07F5.11; 4K617; CE06125; NM_069367; WBGene00006050; WP:CE06125
K07F5.2 K07F5.2 P W All gene names: msp-10; K07F5.2; 4K603; CE03853; NM_069359; WBGene00003425; WP:CE03853 WormBase description: msp-10 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. WormBase CDS description: major sperm protein
K07F5.5 K07F5.5 P W All gene names: K07F5.5; 4K609; CE06120; WBGene00010633; WP:CE06120
K07F5.7 K07F5.7 P W All gene names: K07F5.7; 4K612; CE06122; WBGene00010635; WP:CE06122
K07F5.9 K07F5.9 P W All gene names: ssp-10; K07F5.9; 4K616; CE06124; NM_069366; SSP10_CAEEL; WBGene00006039; WP:CE06124 WormBase description: major sperm protein
K08C9.4 K08C9.4 P W All gene names: col-65; K08C9.4; 1M82; CE18860; NM_060535; WBGene00000641; WP:CE18860
K08D10.7 K08D10.7 P W All gene names: K08D10.7; 4E931; CE07359; Q21319_CAEEL; WBGene00019530; WP:CE07359 WormBase description: K08D10.7 encodes a homolog of human scramblase (PLSCR1; OMIM:604170), which is activated by a rise of intracellular calcium, and which promotes the exposure of phosphatidylserine on the surface of cells undergoing activation, injury, or apoptosis; a close paralog of K08D10.7 is K08D10.8, and other paralogs include F46A8.9, F46A8.10, and Y50E8A.9> Exposure of phosphatidylserine on the surface of apoptotic cells occurs because of a phospholipid scramblase and inactivation of an aminophospolipid translocase that would normally keep the PS on the interior of the cell; by virtue of its similarity to mammalian scramblase, K08D10.7 may promote clearage of apoptotic cells by phagocytosis.
K08D10.8 K08D10.8 P W All gene names: K08D10.8; K08D10.8.1; K08D10.8.2; 4E929; CE07360; Q21318_CAEEL; WBGene00019531; WP:CE07360 WormBase description: K08D10.7 encodes a homolog of human scramblase (PLSCR1; OMIM:604170), which is activated by a rise of intracellular calcium, and which promotes the exposure of phosphatidylserine on the surface of cells undergoing activation, injury, or apoptosis; a close paralog of K08D10.8 is K08D10.7, and other paralogs include F46A8.9, F46A8.10, and Y50E8A.9> Exposure of phosphatidylserine on the surface of apoptotic cells occurs because of a phospholipid scramblase and inactivation of an aminophospolipid translocase that would normally keep the PS on the interior of the cell; by virtue of its similarity to mammalian scramblase, K08D10.8 may promote clearage of apoptotic cells by phagocytosis.
K08D8.5 K08D8.5 P W All gene names: K08D8.5; 4N676; CE06144; WBGene00010659; WP:CE06144
K08E3.1 K08E3.1 P W All gene names: tyr-2; K08E3.1; 3O835; CE18864; NM_067435; WBGene00010661; WP:CE18864 WormBase description: tyrosinase
K08F11.6 K08F11.6 P W All gene names: K08F11.6; 4F492; WBGene00023323
K08F4.5 K08F4.5 P W All gene names: K08F4.5; 4K898; CE06153; WBGene00010679; WP:CE06153
K09C6.8 K09C6.8 P W All gene names: K09C6.8; 5B318; CE12002; WBGene00019562; WP:CE12002
K09E4.1 K09E4.1 P W All gene names: K09E4.1; 2O429; CE19994; WBGene00010719; WP:CE19994
K09F5.2 K09F5.2 P W All gene names: vit-1; K09F5.2; CE04746; NM_076904; VIT1_CAEEL; WBGene00006925; WP:CE04746; XI345 WormBase description: vit-1
K09F6.3 K09F6.3 P W All gene names: K09F6.3; 2C551; CE31563; WBGene00019586; WP:CE31563 WormBase description: protein-tyrosine phosphatase
K09H9.3 K09H9.3 P W All gene names: col-49; K09H9.3; 1D705; CE18038; NM_058705; WBGene00000626; WP:CE18038 WormBase description: cuticular collagen
K09H9.6 K09H9.6 P W All gene names: lpd-6; K09H9.6; 1D714; CE37030; NM_058707; WBGene00003062; WP:CE37030 WormBase description: lpd-6 encodes a predicted rRNA-binding protein that is orthologous to Drosophila Peter Pan and the Saccharomyces cerevisiae SSF1 and SSF2 proteins that are required for ribosomal large subunit maturation; loss of lpd-6 activity via RNAi indicates that, in C. elegans, LPD-6 is required for fat storage and for larval growth and development; based upon its similarity to yeast SSF1 and SSF2, LPD-6 is predicted to be a nucleolar protein.
K11C4.4 K11C4.4 P W All gene names: odc-1; K11C4.4; 5H380; CE12114; DCOR_CAEEL; NM_072351; ODC/1; WBGene00003844; WP:CE12114 WormBase description: odc-1 encodes ornithine decarboxylase, the first enzyme of polyamine biosynthesis that catalyzes the conversion of ornithine to putrescine; ODC-1 is required for development when animals are deprived of exogenous polyamines, which are required for oogenesis and completion of embryogenesis; in addition,ODC-1 may contribute to male fertility; ODC-1 activity is detectable at all developmental stages, with highest levels observed in adults and L4 larvae. WormBase CDS description: ornithine decarboxylase
K11D12.3 K11D12.3 P W All gene names: srr-4; K11D12.3; 5F503; CE30386; NM_071946; WBGene00005655; WP:CE30386
K11D12.4 K11D12.4 P W All gene names: cpt-4; K11D12.4; 5F502; CE12132; WBGene00019644; WP:CE12132 WormBase description: acetyltransferase
K11D2.2 K11D2.2 P W All gene names: asah-1; dod-7; K11D2.2; 1N99; ASAH1_CAEEL; CE12120; NM_060772; WBGene00010769; WP:CE12120 WormBase description: K11D2.2 is orthologous to the human gene N-ACYLSPHINGOSINE AMIDOHYDROLASE (ASAH; OMIM:228000), which when mutated leads to Farber lipogranulomatosis. WormBase CDS description: Human PHP32 protein like
K11G12.1 K11G12.1 P W All gene names: nas-11; K11G12.1; CE36313; CE37260; NAS11_CAEEL; WBGene00003530; WP:CE36313; WP:CE37260; XH333
K11H3.2 K11H3.2 P W All gene names: K11H3.2; 3K933; CE00262; WBGene00010779; WP:CE00262; YM42_CAEEL
K12D12.1 K12D12.1 P W All gene names: K12D12.1; 2M169; CE06184; TOP2_CAEEL; WBGene00010785; WP:CE06184 WormBase description: DNA topoisomerase II
M01E5.5 M01E5.5 P W All gene names: top-1; M01E5.5; 1N889; CE12282; CE12284; NM_060936; TOPOI; WBGene00006595; WP:CE12282; WP:CE12284 WormBase description: top-1 encodes the C. elegans DNA topoisomerase I ortholog; TOP-1 exhibits DNA topoisomerase I activity in vitro and in vivo, this activity is required for normal gonad, germline, and embryonic development; top-1 mRNA is expressed throughout the gonad and during early embryogenesis, with mRNA levels nearly gone by hatching; TOP-1 protein levels are highest in embryos and L1 larvae, decrease by the L3 larval stage and then increase again during L4 and adult stages; in meiotic cells, oocytes, and early embryos, TOP-1 localizes to nuclei, while in later embryos TOP-1 is found in gut nucleoli; during cell division of 1-, 2-, and 4-cell embryos, TOP-1 also localizes to centrosomes. WormBase CDS description: DNA topoisomerase I
M02H5.B M02H5.B P W
M05B5.2 M05B5.2 P W All gene names: MYO2-B; M05B5.2; 1H748; CE31044; WBGene00010870; WP:CE31044
M05D6.1 M05D6.1 P W All gene names: M05D6.1; 2I764; CE03499; WBGene00010874; WP:CE03499 WormBase description: serine/threonine kinase
M110.1 M110.1 P W All gene names: col-76; M110.1; 2I497; CE35898; NM_063325; WBGene00000652; WP:CE35898 WormBase description: collagen
M110.5 M110.5 P W All gene names: dab-1; M110.5; M110.5a.1; M110.5a.2; 2I519; CE36393; CE36446; CE37844; NM_063329; NM_063330; NM_063331; Q9U3A6_CAEEL; WBGene00000894; WP:CE36393; WP:CE36446; WP:CE37844 WormBase description: dab-1 encodes an ortholog of the cytoplasmic adaptor protein DISABLED, required for normal molting and meiotic arrest; DAB-1 is also required for EGL-17 secretion from vulval cells, and thus indirectly for normal sex myoblast (SM) migration and egg-laying; DAB-1 contains a conserved PTB domain and signals that confer localization to Golgi-proximal vesicles, and DAB-1 localizes to vesicular structures in vivo; dab-1 is expressed in ventral precursor cells, and DAB-1 prevents EGL-17 protein accumulation in them; dab-1 is also expressed in other cells (anchor cell, sheath cells, etc.) but has no obvious function in them; DAB-1 binds the cytoplasmic domains of either LRP-1 or LRP-2 in yeast two-hybrid experiments; dab-1(gk291) and dab-1(RNAi) animals have similar defects in molting, EGL-17 secretion from VPCs, SM migration, and egg-laying; dab-1(RNAi) does not enhance the SM phenotypes of lrp-1(RNAi) or lrp-2(RNAi), suggesting that these genes act in concert to promote normal EGL-17 secretion and SM migration; in vitro, DAB-1 binds to the ear domains of APT-4 (strongly) and of APT-1 and APT-9 (weakly); genetically, dab-1(RNAi) functions as part of the vab-1 pathway in oocytes inhibiting meiotic maturation, and DAB-1 is found in oocyte cytoplasm.
M176.4 M176.4 P W All gene names: M176.4; 2J711; CE33289; WBGene00010943; WP:CE33289
M195.1 M195.1 P W All gene names: col-77; M195.1; 2I648; CE03514; NM_063358; WBGene00000653; WP:CE03514 WormBase description: cuticle collagen
M60.2 M60.1 P W
M60.4 M60.3 P W
M88.1 M88.1 P W All gene names: ugt-62; M88.1; M88.1.1; M88.1.2; 3F628; CE01036; WBGene00010904; WP:CE01036 WormBase description: UDP-glucuronosyltransferase
PDB1.1 PDB1.1 P W All gene names: PDB1.1; CE31209; CE39603; CE39604; NM_076878; WBGene00019803; WP:CE31209; WP:CE39603; WP:CE39604; XI176
R02D5.7 R02D5.7 P W All gene names: R02D5.7; 5O960; CE29435; WBGene00010980; WP:CE29435
R02F11.1 R02F11.1 P W All gene names: R02F11.1; 5F281; CE12496; O16364_CAEEL; WBGene00019839; WP:CE12496
R04B5.9 R04B5.9 P W All gene names: ugt-47; R04B5.9; 5K578; CE37984; WBGene00011006; WP:CE37984 WormBase description: UDP-glucuronosyltransferase
R07B1.10 R07B1.10 P W All gene names: lec-8; R07B1.10; R07B1.10.1; R07B1.10.2; CE26721; LEC8_CAEEL; NM_077248; WBGene00002271; WP:CE26721; XK469 WormBase description: galaptin domain
R07E5.1 R07E5.1 P W All gene names: R07E5.1; 3F501; CE00658; WBGene00011109; WP:CE00658
R07E5.15 R07E5.15 P W All gene names: R07E5.15; 3F491; CE18126; WBGene00011120; WP:CE18126
R07E5.6 R07E5.6 P W All gene names: R07E5.6; 3F489; CE18124; WBGene00011114; WP:CE18124 WormBase description: Coiled-coil protein
R08C7.8 R08C7.8 P W All gene names: R08C7.8; 4F198; CE07431; WBGene00019951; WP:CE07431 WormBase description: serine/threonine protein phosphatase
R08F11.3 R08F11.3 P W All gene names: cyp-33C8; R08F11.3; 5E272; CE12584; NM_071650; WBGene00019967; WP:CE12584 WormBase description: cytochrome P450
R09E10.6 R09E10.6 P W All gene names: R09E10.6; 4L58; CE06288; WBGene00011176; WP:CE06288
R10D12.9 R10D12.9 P W All gene names: R10D12.9; 5O435; CE12688; WBGene00011190; WP:CE12688
R10E9.2 R10E9.2 P W All gene names: R10E9.2; 3F52; CE01051; WBGene00011214; WP:CE01051
R11A8.1 R11A8.1 P W All gene names: R11A8.1; 4L120; CE06299; WBGene00011236; WP:CE06299
R11H6.4 R11H6.4 P W All gene names: R11H6.4; 5P89; CE12776; WBGene00011252; WP:CE12776
R12E2.15 R12E2.15 P W All gene names: R12E2.15; 1E716; CE18147; WBGene00020040; WP:CE18147
R13H9.1 R13H9.1 P W All gene names: R13H9.1; 4F833; CE07447; WBGene00020070; WP:CE07447
R13H9.2 R13H9.2 P W All gene names: msp-57; R13H9.2; 4F827; MSP55_CAEEL; NM_068312; WBGene00003450 WormBase description: msp-57 encodes a member of the major sperm protein family. WormBase CDS description: major sperm protein (MSP-57)
R13H9.4 R13H9.4 P W All gene names: msp-53; R13H9.4; 4F828; NM_068313; WBGene00003446 WormBase description: msp-53 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-53 has a C. briggsae homolog as identified by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. WormBase CDS description: major sperm protein (MSP-53)
R13H9.5 R13H9.5 P W All gene names: R13H9.5; 4F830; CE07449; WBGene00020071; WP:CE07449
R13H9.6 R13H9.6 P W All gene names: R13H9.6; 4F832; CE07450; WBGene00020072; WP:CE07450
R52.2 R52.2 P W All gene names: R52.2; 2C417; CE12826; WBGene00020074; WP:CE12826
R57.1 R57.1 P W All gene names: R57.1; R57.1b.1; R57.1b.2; R57.1c.1; R57.1c.2; R57.1c.3; CE12844; CE30114; CE37270; GCP2_CAEEL; WBGene00020082; WP:CE12844; WP:CE30114; WP:CE37270; XA925 WormBase description: trans-membrane protein
R74.2 R74.2 P W All gene names: R74.2; 3F279; CE23931; WBGene00011278; WP:CE23931
R74.3 R74.3 P W All gene names: xbp-1; R74.3; R74.3.1; R74.3.2; 3F285; CE01056; WBGene00006959; WP:CE01056 WormBase description: xbp-1 encodes a bZIP transcription factor orthologous to yeast Hac1 and mammalian X box-binding protein 1 (XBP-1, OMIM:194355); XBP-1 is required for the unfolded protein response (UPR) that counteracts cellular stress induced by accumulation of unfolded proteins in the endoplasmic reticulum (ER); XBP-1 mRNA is spliced by the IRE-1 endoribonuclease to promote translation of transcriptionally active XBP-1 that positively regulates UPR gene expression to maintain ER homeostasis and promote normal development. WormBase CDS description: X box DNA binding protein-1
T01B10.2 T01B10.2 P W All gene names: grd-14; T01B10.2; CE07456; NM_077040; WBGene00001703; WP:CE07456; XJ117 WormBase description: grd-14 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground domain; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-14 is required for normal growth to full size, locomotion, and vulval morphogenesis; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
T01B11.4 T01B11.4 P W All gene names: tag-316; T01B11.4; 4J224; CE12898; WBGene00020140; WP:CE12898 WormBase description: ADP/ATP translocase
T01B7.7 T01B7.7 P W All gene names: rol-6; T01B7.7; 2J23; CE03591; NM_063457; ROL6_CAEEL; WBGene00004397; WP:CE03591 WormBase description: The rol-6 gene encodes a cuticle collagen related to human collagen alpha 1 (III) chain precursor (OMIM:120180), and is required for normal cuticular morphology; ROL-6 interacts with SQT-1, a closely related cuticle collagen, and is expressed at all stages from L2 to adult with transcripts detected at each of the molts preceding these stages. WormBase CDS description: cuticle collagen ROL-6
T01D1.6 T01D1.6 P W All gene names: abu-11; pqn-61; T01D1.6; 2A484; CE28071; NM_061278; P91419_CAEEL; WBGene00000034; WP:CE28071 WormBase description: abu-11 encodes a transmembrane protein with a predicted signal sequence, a glutamine/asparagine-rich domain and multiple cysteine-rich repeats (DUF139); abu-11 expression is induced by blockage of the unfolded-protein response in the endoplasmic reticulum, and ABU-11 may help protect the organism from damage by improperly folded nascent protein.
T01G6.7 T01G6.7 P W All gene names: nhr-55; T01G6.7; 5A957; CE37786; NHR55_CAEEL; NM_070814; WBGene00003645; WP:CE37786 WormBase description: nhr-55 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain. WormBase CDS description: zinc finger protein
T02E1.6 T02E1.6 P W All gene names: T02E1.6; 1I789; CE38218; WBGene00011378; WP:CE38218
T02E9.2 T02E9.2 P W All gene names: grl-7; T02E9.2; T02E9.2a.1; T02E9.2a.2; 5L826; CE13064; CE38539; NM_073481; O18015_CAEEL; WBGene00001716; WP:CE13064; WP:CE38539 WormBase description: grl-7 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-7 is expressed in intestine, hypodermis, and seam cells; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
T02G5.8 T02G5.8 P W All gene names: kat-1; T02G5.8; 2H367; CE29990; NM_063054; WBGene00002183; WP:CE29990 WormBase description: kat-1 encodes a homolog of the human gene ACAT1, which when mutated leads to alpha-methylacetoaceticaciduria (OMIM:203750). WormBase CDS description: acetoacetyl-C0A thiolase
T03D3.4 T03D3.4 P W All gene names: srh-36; T03D3.4; 5D296; CE25098; NM_071363; WBGene00005259; WP:CE25098 WormBase description: 7TM chemoreceptor, srh family
T03F6.3 T03F6.3 P W All gene names: T03F6.3; 3O479; CE16337; GNPI_CAEEL; WBGene00011399; WP:CE16337 WormBase description: Glucosamine-6-phosphate isomerase
T04C9.4 T04C9.5 P W
T04D3.5 T04D3.5 P W All gene names: T04D3.5; 1N922; CE13161; WBGene00011434; WP:CE13161
T05A10.3 T05A10.3 P W All gene names: T05A10.3; CE03635; WBGene00011460; WP:CE03635; XL407 WormBase description: Transthyretin-like family
T05A10.5 T05A10.5 P W All gene names: T05A10.5; CE13189; WBGene00011462; WP:CE13189; XL408 WormBase description: testes-specific protein like
T05C12.1 T05C12.1 P W All gene names: T05C12.1; 2I461; CE02312; WBGene00011466; WP:CE02312 WormBase description: serine/threonine kinase
T05C12.10 T05C12.10 P W All gene names: qua-1; T05C12.10; 2I493; CE34989; M110; NM_063324; WBGene00004264; WP:CE34989 WormBase description: qua-1 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, a Qua domain, a 5W repeat, an extended region of low-complexity sequence, and a Hint/Hog domain; QUA-1 is conserved among nematodes from Caenorhabditis to Brugia; QUA-1 is expressed prior to molting in hyp1 to hyp11 hypodermal cells, but not in seam cells, and ceases to be expressed after each molting cycle or in gravid adults no longer molting; QUA-1 is strongly required for normal molting, with lethal molting defects in qua-1 mutants and severe defects in qua-1(RNAi) animals; similar molting defects in RNAi of ptr-4 and ptr-23 (encoding Dispatched homologs) suggest that PTR-4 and PTR-23 may export QUA-1 from hypodermal cells synthesizing it; other sites of QUA-1 expression include intestinal and rectal cells, excretory duct and pore cells, sensilla support cells, the P cell lineage in L1, body wall muscle, and the adult reproductive system; QUA-1 is also required for normal adult alae formation, growth to full size, cuticle adhesion, locomotion, and male tail development; the Hint/Hog domain is predicted to cut QUA-1 into two halves and then covalently link cholesterol to the C-terminus of the Qua domain; the Qua domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and the Qua domain has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; both Qua and Hint/Hog domains are required for transgenic rescue of a lethal qua-1 allele; defects in both qua-1 mutants and qua-1(RNAi) animals; all of QUA-1's functions may reflect common defects in cholesterol-dependent hedgehog-like signalling. WormBase CDS description: hedgehog-like protein
T05F1.8 T05F1.8 P W All gene names: T05F1.8; 1K219; CE13249; WBGene00011493; WP:CE13249 WormBase description: mitochondrial phosphate carrier protein
T05G5.6 T05G5.6 P W All gene names: ech-6; T05G5.6; T05G5.6.1; T05G5.6.2; 3K842; CE00318; ECHM_CAEEL; NM_066755; WBGene00001155; WP:CE00318 WormBase description: Enoyl-CoA hydratase
T05H4.5 T05H4.5 P W All gene names: T05H4.5; T05H4.5.1; T05H4.5.2; 5G917; CE13277; WBGene00020268; WP:CE13277 WormBase description: The T05H4.5 gene encodes an ortholog of the human gene NADH-CYTOCHROME B5 REDUCTASE (DIA1), which when mutated leads to methemoglobinemia (OMIM:250800). WormBase CDS description: NADH-cytochrome B5 reductase
T06C10.3 T06C10.3 P W All gene names: T06C10.3; 4I637; CE04901; WBGene00020289; WP:CE04901
T06C10.6 T06C10.6 P W All gene names: kin-26; T06C10.6; 4I640; CE04904; NM_068908; WBGene00002208; WP:CE04904 WormBase description: tyosine-protein kinase
T06E4.8 T06E4.8 P W All gene names: T06E4.8; 5K102; CE23951; WBGene00011535; WP:CE23951
T08A9.7 T08A9.7 P W All gene names: spp-3; T08A9.7; T08A9.7.1; T08A9.7.2; CE31233; NM_076834; WBGene00004988; WP:CE31233; XH934 WormBase description: 7TM chemoreceptor, spp family
T09B4.7 T09B4.7 P W All gene names: T09B4.7; 1G734; CE13469; WBGene00020381; WP:CE13469
T10C6.11 T10C6.11 P W All gene names: his-4; T10C6.11; 5Q520; CE16386; NM_074630; WBGene00001878; WP:CE16386 WormBase description: his-4 encodes an H2B histone. WormBase CDS description: histone H2B
T10C6.12 T10C6.12 P W All gene names: his-3; T10C6.12; 5Q521; CE04501; NM_074631; WBGene00001877; WP:CE04501 WormBase description: his-3 encodes an H2A histone; by homology, HIS-3 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-3 is a replication-dependent histone locus that resides in the HIS1 cluster on chromosome V. WormBase CDS description: histone H2A
T10E10.1 T10E10.1 P W All gene names: col-168; T10E10.1; CE23970; NM_076659; WBGene00000741; WP:CE23970; XG945 WormBase description: collagen
T10H4.12 T10H4.12 P W All gene names: cpr-3; T10H4.12; 5P778; CE27590; CPR3_CAEEL; NM_074389; WBGene00000783; WP:CE27590 WormBase description: cathepsin protease
T11B7.3 T11B7.3 P W All gene names: col-118; T11B7.3; 4J613; CE03649; NM_069131; WBGene00000692; WP:CE03649 WormBase description: cuticle collagen
T12B5.10 T12B5.10 P W All gene names: fbxa-60; T12B5.10; 3B560; CE20067; WBGene00020456; WP:CE20067 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
T12G3.1 T12G3.1 P W All gene names: T12G3.1; T12G3.1.1; T12G3.1.2; 4M801; CE37554; Q22436_CAEEL; WBGene00011737; WP:CE37554 WormBase description: Drosphila REF (2)P like
T13F2.11 T13F2.11 P W All gene names: msp-78; T13F2.11; 4K535; CE13638; MSP78_CAEEL; NM_069341; WBGene00003465; WP:CE13638 WormBase description: msp-78 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. WormBase CDS description: major sperm protein
T13F2.9 T13F2.9 P W All gene names: T13F2.9; 4K533; CE13635; WBGene00011748; WP:CE13635
T14B4.4 T14B4.4 P W All gene names: tsp-10; T14B4.4; T14B4.4b.1; T14B4.4b.2; 2H9; CE02047; CE39776; NM_062968; WBGene00006636; WP:CE02047; WP:CE39776 WormBase description: transpanin
T14B4.6 T14B4.6 P W All gene names: dpy-2; rol-2; T14B4.6; 2H5; CE04953; DPY2_CAEEL; NM_062966; WBGene00001064; WP:CE04953 WormBase description: The dpy-2 gene encodes an unusual cuticular collagen that is required for maintaining the normal body length of the animal in later larval stages; dpy-2 interacts with other cuticular collagens such as dpy-10 and sqt-1, and suppresses mutations in glp-1, mup-1, and emb-5.
T14G10.8 T14G10.8 P W All gene names: T14G10.8; CE06454; WBGene00011777; WP:CE06454
T15B7.2 T15B7.2 P W All gene names: T15B7.2; T15B7.2.1; T15B7.2.2; 5H319; CE33319; WBGene00020517; WP:CE33319
T15H9.5 T15H9.5 P W All gene names: T15H9.5; 2J900; CE01668; WBGene00011790; WP:CE01668; YRY5_CAEEL
T16A9.5 T16A9.5 P W All gene names: T16A9.5; 5O694; CE13728; WBGene00011795; WP:CE13728
T16H12.6 T16H12.6 P W All gene names: kel-10; T16H12.6; 3L188; CE36451; KEL10_CAEEL; NM_066840; WBGene00002186; WP:CE36451 WormBase description: MIPP repeats
T18H9.1 T18H9.1 P W All gene names: grd-6; T18H9.1; 5J705; CE35772; NM_072988; WBGene00001695; WP:CE35772 WormBase description: grd-6 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity proline-rich domain, and a C-terminal Ground domain; GRD-6 is expressed in hypodermis and in various neurons, in both head and tail, and the PVT interneuron; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-6 has no obvious function in RNAi assays.
T19B10.2 T19B10.2 P W All gene names: phi-59; T19B10.2; T19B10.2.1; T19B10.2.2; 5L703; CE16413; WBGene00011831; WP:CE16413
T19D12.4 T19D12.4 P W All gene names: T19D12.4; 2G925; CE17238; CE39409; WBGene00020579; WP:CE17238; WP:CE39409
T20B6.3 T20B6.3 P W All gene names: T20B6.3; 3D984; CE13778; WBGene00020599; WP:CE13778
T20D3.2 T20D3.2 P W All gene names: T20D3.2; T20D3.2.1; T20D3.2.2; 4K94; CE03671; WBGene00011856; WP:CE03671
T21D12.2 T21D12.2 P W All gene names: col-100; dpy-9; T21D12.2; 4B12; CE35021; NM_067488; WBGene00001071; WP:CE35021 WormBase description: dpy-9 encodes a cuticular collagen family member with similarity to human collagen alpha 5, type IV, and affects body length. WormBase CDS description: cuticular collagen
T21G5.4 T21G5.4 P W All gene names: T21G5.4; 1H448; CE13894; WBGene00020661; WP:CE13894
T21H3.1 T21H3.1 P W All gene names: T21H3.1; 5B657; CE13898; CE38551; WBGene00020662; WP:CE13898; WP:CE38551
T22B3.3 T22B3.3 P W All gene names: T22B3.3; 4M466; CE03695; WBGene00011911; WP:CE03695
T22C1.8 T22C1.8 P W All gene names: T22C1.8; 1I532; CE18278; WBGene00011918; WP:CE18278 WormBase description: tyrosine specific protein phosphatase
T22D1.3 T22D1.3 P W All gene names: T22D1.3; T22D1.3b.1; T22D1.3b.2; 4H681; CE30188; CE33940; WBGene00020682; WP:CE30188; WP:CE33940 WormBase description: inosine monophosphate dehydrogenase
T23B3.5 T23B3.5 P W All gene names: T23B3.5; 1H282; CE14016; WBGene00020713; WP:CE14016
T23F11.2 T23F11.2 P W All gene names: T23F11.2; 3F744; CE01095; WBGene00011954; WP:CE01095
T23F6.4 T23F6.4 P W All gene names: rbd-1; T23F6.4; T23F6.4.1; T23F6.4.2; 4N493; CE18963; NM_070031; WBGene00004315; WP:CE18963 WormBase description: RNA recognition motif. (aka RRM, RBD, or RNP domain) (6 domains)
T25B9.6 T25B9.6 P W All gene names: T25B9.6; 4L523; CE35628; WBGene00012012; WP:CE35628
T25B9.9 T25B9.9 P W All gene names: T25B9.9; T25B9.9.1; T25B9.9.2; 4L541; 6PGD_CAEEL; CE06508; WBGene00012015; WP:CE06508 WormBase description: 6-phosphogluconate dehydrogenase
T25C8.3 T25C8.3 P W All gene names: gln-4; T25C8.3; 3O688; NM_067407; WBGene00001605
T25E4.1 T25E4.1 P W All gene names: T25E4.1; 2F869; CE28493; WBGene00020803; WP:CE28493; YR01_CAEEL
T26A5.9 T26A5.9 P W All gene names: dlc-1; T26A5.9; T26A5.9.1; T26A5.9.2; 3H554; CE00788; DYL1_CAEEL; NM_066021; WBGene00001005; WP:CE00788 WormBase description: dlc-1 encodes a dynein light chain type 1 that affects pronuclear migrations and thus affects embryonic viability; also affects fertility, body wall morphology and integrity.
T27A10.4 T27A10.4 P W
T27A10.6 T27A10.6 P W All gene names: T27A10.6; T27A10.6.1; T27A10.6.2; CE30193; WBGene00020846; WP:CE30193; XE208
T27A3.3 T27A3.3 P W All gene names: ssp-16; T27A3.3; 1G679; CE14221; NM_059361; SSP16_CAEEL; WBGene00006044; WP:CE14221
T27A3.4 T27A3.4 P W All gene names: T27A3.4; 1G675; CE14223; WBGene00020840; WP:CE14223
T27A3.5 T27A3.5 P W All gene names: T27A3.5; 1G676; CE34379; WBGene00020841; WP:CE34379
T27E4.7 T27E4.7 P W All gene names: T27E4.7; T27E4.7.1; T27E4.7.2; 5J556; CE14259; WBGene00020865; WP:CE14259
T27E7.1 T27E7.1 P W All gene names: T27E7.1; 4P285; CE16505; WBGene00012087; WP:CE16505
T28B4.3 T28B4.3 P W All gene names: T28B4.3; CE14325; WBGene00020886; WP:CE14325; XH214
T28C6.4 T28C6.4 P W All gene names: T28C6.4; 4J588; NM_069125; WBGene00000691 WormBase description: cuticle collagen
T28H11.1 T28H11.1 P W All gene names: ssq-4; T28H11.1; 4F781; CE30698; NM_068303; WBGene00006053; WP:CE30698
T28H11.5 T28H11.5 P W All gene names: ssq-2; T28H11.5; 4F761; CE14377; NM_068297; WBGene00006051; WP:CE14377
T28H11.6 T28H11.6 P W All gene names: ssp-11; T28H11.6; T28H11.6.1; T28H11.6.2; 4F764; NM_068298; SSP9_CAEEL; WBGene00006040
T28H11.7 T28H11.7 P W All gene names: T28H11.7; 4F780; CE14380; WBGene00020905; WP:CE14380
VW02B12L.1 VW02B12L.1 P W All gene names: vha-6; VW02B12L.1; VW02B12L.1.1; VW02B12L.1.2; 2L726; CE18980; NM_064035; WBGene00006915; WP:CE18980 WormBase description: vha-6 encodes an ortholog of subunit a of the membrane-bound (V0) domain of vacuolar proton-translocating ATPase (V-ATPase); VHA-6 is orthologous to human ATP6N1A (OMIM:192130), ATP6V0A2, ATP6V0A4 (OMIM:605239, mutated in distal renal tubular acidosis), and TCIRG1 (OMIM:604592, mutated in osteopetrosis); VHA-6 is expressed in germline (P2 through Z3 cells until the comma stage), on the apical surface of postembryonic intestinal cells, and at the junction between pharynx and intestine; VHA-6 is required for growth and survival past the L1 larval stage; vha-6(RNAi) animals arrest as L1 larvae and remain alive (but do not grow) for one week; in S. cerevisiae, different V0 a-subunits (Stv1p and Vph1p) direct the assembly of V-ATPases to different membranes and organelles, suggesting that the profusion of such subunits in C. elegans (co-orthologous VHA-5, VHA-6, VHA-7, and six UNC-32 isoforms) may have a similar function; VHA-6 is predicted to capture protons from V-ATPase transmembrane rotor components and export the protons across the membrane. WormBase CDS description: vacuolar ATP synthase
VZK822L.1 VZK822L.1 P W All gene names: fat-6; VZK822L.1; 4M678; CE18302; NM_069854; WBGene00001398; WP:CE18302 WormBase description: fat-6 encodes a delta-9 fatty acid desaturase that is predicted to be mitochondrial. WormBase CDS description: acyl-CoA desaturase
W01B6.2 W01B6.2 P W All gene names: W01B6.2; 4K838; CE03754; WBGene00012169; WP:CE03754 WormBase description: serine/threonine kinase
W01B6.6 W01B6.6 P W All gene names: W01B6.6; 4K845; CE03758; WBGene00012173; WP:CE03758 WormBase description: tyrosine phosphatase
W01C9.4 W01C9.4 P W All gene names: W01C9.4; 2I837; CE02370; WBGene00012177; WP:CE02370; YWC4_CAEEL WormBase description: 2,4-dienoyl-CoA reductase
W01F3.2 W01F3.2 P W All gene names: W01F3.2; 5V131; CE16530; WBGene00012185; WP:CE16530
W03B1.1 W03B1.1 P W All gene names: W03B1.1; 4F99; CE14488; WBGene00020971; WP:CE14488
W03D8.10 W03D8.10 P W All gene names: W03D8.10; 1D355; CE18330; WBGene00020991; WP:CE18330
W03D8.5 W03D8.5 P W All gene names: W03D8.5; 1D385; CE37996; WBGene00020987; WP:CE37996
W03D8.9 W03D8.9 P W All gene names: W03D8.9; 1D354; CE26983; WBGene00020990; WP:CE26983
W03F8.2 W03F8.2 P W All gene names: W03F8.2; 4F957; CE35040; WBGene00020992; WP:CE35040 WormBase description: protein kinase
W03G1.2 W03G1.2 P W All gene names: W03G1.2; 4B279; CE17280; WBGene00021010; WP:CE17280
W04E12.4 W04E12.4 P W All gene names: W04E12.4; 5U213; CE34100; WBGene00012249; WP:CE34100
W05G11.3 W05G11.3 P W All gene names: col-88; W05G11.3; W05G11.3.1; W05G11.3.2; 3A659; CE14628; NM_064730; WBGene00000663; WP:CE14628 WormBase description: cuticular collagen
W06A7.5 W06A7.5 P W All gene names: nspa-8; W06A7.5; 5P306; CE14672; NM_074253; WBGene00012294; WP:CE14672
W06B3.2 W06B3.2 P W All gene names: sma-5; W06B3.2; CE31629; CE31630; CE38984; CE39526; NM_171782; NM_171783; WBGene00004859; WP:CE31629; WP:CE31630; WP:CE38984; WP:CE39526; XM616 WormBase description: sma-5 encodes a serine/threonine kinase homologous to the mammalian MAP kinase MAPK7/ERK5 (OMIM:602521, required for development of extraembryonic vasculature and embryonic cardiovasculature); SMA-5 is required for normal body size morphogenesis, growth rates, and intestinal granule distribution, and for regulating the size of the intestine, body wall muscle, and hypodermis, as well as the number of intestinal nuclei; SMA-5 is expressed in the intestine and in hypodermal seam cells.
W06D4.2 W06D4.2 P W All gene names: W06D4.2; 1J633; CE16544; WBGene00012296; WP:CE16544
W07B8.1 W07B8.1 P W All gene names: W07B8.1; 5B617; CE14674; WBGene00021070; WP:CE14674 WormBase description: thiol protease
W07G4.5 W07G4.5 P W All gene names: W07G4.5; 5N529; CE03793; Q27408_CAEEL; WBGene00012339; WP:CE03793
W08A12.2 W08A12.2 P W All gene names: W08A12.2; 5E164; CE14698; WBGene00021079; WP:CE14698
W08D2.4 W08D2.4 P W All gene names: fat-3; W08D2.4; 4K569; CE25153; NM_069351; Q23221_CAEEL; WBGene00001395; WP:CE25153 WormBase description: The fat-3 gene encodes a delta-6 fatty acid desaturase ('linoleoyl-CoA desaturase') containing an N-terminal cytochrome b5 domain; FAT-3 expressed in yeast uses linoleic and alpha-linolenic acid as substrates; FAT-3 is absolutely required in vivo for synthesis of delta-6 fatty acids, and also required for fully normal synthesis of C20 fatty acids; FAT-3 is required for a normally fast growth rate and movement speed, and for normal defecation rhythms and fertility.
W08E12.5 W08E12.G P W
W08E12.1 W08E12.K P W
W08E3.1 W08E3.1 P W All gene names: snr-2; W08E3.1; W08E3.1.1; W08E3.1.2; 1N931; CE14704; NM_060947; RSMB_CAEEL; WBGene00004915; WP:CE14704 WormBase description: small nuclear ribonucleoprotein (SNRNP)
W09C3.6 W09C3.6 P W All gene names: gsp-3; W09C3.6; 1F278; CE14754; NM_059028; WBGene00021113; WP:CE14754 WormBase description: serine/threonine protein phosphatase PP1
W09C3.8 W09C3.8 P W All gene names: W09C3.8; 1F284; CE39115; WBGene00021115; WP:CE39115
W09G12.7 W09G12.7 P W All gene names: W09G12.7; 4B983; CE18346; O45198_CAEEL; WBGene00021121; WP:CE18346
W10C8.5 W10C8.5 P W All gene names: W10C8.5; W10C8.5.1; W10C8.5.2; W10C8.5.3; 1D422; CE18353; WBGene00021128; WP:CE18353 WormBase description: ATP transferase
Y106G6A.2 Y106G6A.3 P W
Y106G6A.4 Y106G6A.4 P W All gene names: Y106G6A.4; 1K509; CE30569; WBGene00013696; WP:CE30569
Y106G6E.3 Y106G6E.3 P W All gene names: Y106G6E.3; 1K795; CE20407; WBGene00013707; WP:CE20407
Y110A7A.9 Y110A7A. P W
Y113G7C.1 Y113G7C.1 P W All gene names: Y113G7C.1; Y113G7C.B; 5U793; CE23304; WBGene00013771; WP:CE23304 WormBase description: Protein-tyrosine phosphatase
Y116A8C.38 Y116A8C.38 P W All gene names: Y116A8C.38; 4S77; CE33848; WBGene00013811; WP:CE33848
Y43F8C.5 Y116F11A.ZZ1 P W
Y11D7A.11 Y11D7A.11 P W All gene names: col-120; Y11D7A.11; 4K26; CE20194; NM_069216; Q9XWR2_CAEEL; WBGene00000694; WP:CE20194
Y11D7A.15 Y11D7A.15 P W All gene names: Y11D7A.15; WBGene00012438
Y13C8A.B Y13C8A.B P W
Y15E3A.5 Y15E3B.F P W
Y19D10A.J Y19D10A.J P W
Y22F5A.4 Y22F5A.4 P W All gene names: lys-1; Y22F5A.4; Y22F5A.4.1; Y22F5A.4.2; 5K759; CE16605; NM_073241; O62415_CAEEL; WBGene00003090; WP:CE16605
F55F10.1 Y24D9A.E, Y24D9A.F P W
F55F10.1 Y24D9A.E, Y24D9A.F P W
Y24F12A.C Y24F12A.C P W
Y25C1A.1 Y25C1A.1 P W All gene names: Y25C1A.1; Y25C1A.O; 2D405; CE21468; WBGene00021288; WP:CE21468
Y27F2A.3 Y27F2A.H P W
Y37D8A.12 Y37D8A.12 P W All gene names: Y37D8A.12; Y37D8A.12a.1; Y37D8A.12a.2; 3N969; CE20216; CE28421; WBGene00012552; WP:CE20216; WP:CE28421
Y37D8A.13 Y37D8A.13 P W All gene names: adm-1; max-3; unc-71; Y37D8A.13; 3N972; CE20217; NM_067279; WBGene00006804; WP:CE20217 WormBase description: unc-71 encodes an ADAM, a disintegrin and metalloprotease-containing transmembrane protein that is a member of the metzincin superfamily of proteases; UNC-71 is required non-cell autonomously for motor axon guidance and sex myoblast migration; UNC-71 does not appear to have an active metalloprotease domain, but functions with UNC-6/netrin and integrins INA-1/PAT-3 to provide guidance cues during axonal migration; UNC-71 is expressed in a restricted pattern in the excretory and excretory gland cells, some head neurons, the sphincter muscles, and hypodermal cells surrounding the vulva. WormBase CDS description: Disintegrin
Y37D8A.19 Y37D8A.19 P W All gene names: Y37D8A.19; Y37D8A.19.1; Y37D8A.19.2; 3O19; CE20223; WBGene00012557; WP:CE20223
Y37E11B.10 Y37E11B.10 P W All gene names: Y37E11B.10; 4E368; CE28114; CE33857; CE33858; WBGene00021381; WP:CE28114; WP:CE33857; WP:CE33858
W06H8.8 Y38B5A.B P W
Y38C1BA.3 Y38C1BA.A P W
Y38H8A.3 Y38H8A.3 P W All gene names: Y38H8A.3; 4O239; CE18365; WBGene00012637; WP:CE18365 WormBase description: serine/threonine kinase
Y39A1A.2 Y39A1A.2 P W All gene names: Y39A1A.2; 3L690; CE37800; WBGene00012642; WP:CE37800
Y39E4A.1 Y39E4A.1 P W All gene names: Y39E4A.1; 3O41; CE16615; WBGene00012711; WP:CE16615
Y39G10A_237.B Y39G10A_237.B P W
Y41E3.2 Y41E3.2 P W All gene names: col-134; dpy-4; Y41E3.2; 4P750; CE18370; NM_070407; WBGene00001066; WP:CE18370 WormBase description: dpy-4 encodes a cuticle collagen; dpy-4 activity is required for normal body morphology, locomotion, and larval development. WormBase CDS description: CUTICLE COLLAGEN 1
Y43C5A.1 Y43C5A.1 P W All gene names: Y43C5A.1; 4L34; CE19150; WBGene00012781; WP:CE19150
Y43F8A.2 Y43F8A.2 P W All gene names: Y43F8A.2; Y43F8A.B; 5T849; CE24284; WBGene00012809; WP:CE24284
Y43F8C.1 Y43F8C.1 P W All gene names: nlp-25; Y43F8C.1; 5U81; CE21899; NM_075400; Q9XWP3_CAEEL; WBGene00003763; WP:CE21899
Y46C8AL.1 Y46C8_100.D P W
Y46G5A.14 Y46G5.O P W
Y46H3C.C Y46H3C.C P W
Y46H3C_14.C Y46H3C_14.C P W
Y46H3C.4 Y46H3C_14.D P W
Y47D3A.31 Y47D3A.F P W
Y48B6A.8 Y48B6A.8 P W All gene names: ace-3; Y48B6A.8; 2O499; CE28131; NM_064562; WBGene00000037; WP:CE28131 WormBase description: ace-3 encodes one of four C. elegans acetylcholinesterases (AChE); ACE-3 represents ~5% of the total AChE activity in C. elegans and in vitro, hydrolyzes acetylthio-, butyrylthio-, and propionylthiocholine substrates with equal efficiency; although loss-of-function mutations in ace-3 result in no obvious defects, animals doubly mutant with ace-1 or ace-2 have slight defects in backward locomotion and animals triply mutant for ace-1, -2, and -3 arrest as unhatched, yet fully developed, embryos; ace-3 is the downstream gene in an operon with a fourth AChE-encoding gene, ace-4, and transcriptional reporter fusions with ace-4 upstream sequences direct expression in pharyngeal muscles pm3, 4, 5, and 7, the two CAN (canal associated neuron) cells, midbody dorsal body wall muscles in larvae, and several neurons in the head and anal ganglion
Y49E10.6 Y49E10.6 P W All gene names: his-72; Y49E10.6; Y49E10.6.1; Y49E10.6.2; Y49E10.A; 3N456; CE22223; H332_CAEEL; NM_067207; WBGene00001946; WP:CE22223 WormBase description: his-72 encodes an H3 histone required for embryonic viability. WormBase CDS description: Core histone H2A/H2B/H3/H4
Y49E10.8 Y49E10.8 P W All gene names: Y49E10.8; 3N477; WBGene00014903
Y49F6B.10 Y49F6B.P P W
Y51A2B.1 Y51A2B.1 P W All gene names: Y51A2B.1; 5S847; CE16655; WBGene00013065; WP:CE16655
Y53C10A.2 Y53C10A.2 P W All gene names: Y53C10A.2; 1M560; CE22370; WBGene00013133; WP:CE22370
Y54E2A.7 Y54E2A.7 P W All gene names: Y54E2A.7; 2P58; CE20306; WBGene00013192; WP:CE20306
Y54E2A.9 Y54E2A.9 P W All gene names: Y54E2A.9; 2P68; CE20308; WBGene00013194; WP:CE20308
Y54E5A.1 Y54E5A.1 P W All gene names: Y54E5A.1; 1P280; CE28791; Q9XWK1_CAEEL; WBGene00013197; WP:CE28791
Y57G11A.2 Y57G11A.2 P W All gene names: Y57G11A.2; 4P282; CE16664; WBGene00013290; WP:CE16664
Y57G11C.5 Y57G11C.5 P W All gene names: Y57G11C.5; 4P520; CE37440; WBGene00013303; WP:CE37440
Y57G7A.6 Y57G7A.6 P W All gene names: Y57G7A.6; 2B572; CE19635; WBGene00021969; WP:CE19635
Y59E9AL.3 Y59E9_118.A P W
Y59E9_118.E Y59E9_118.E P W
Y59E9_120.C Y59E9_120.C P W
Y5F2A.1 Y5F2A.1 P W All gene names: Y5F2A.1; Y5F2A.1.1; Y5F2A.1.2; 4L828; CE19022; UP04_CAEEL; WBGene00012382; WP:CE19022 WormBase description: Transthyretin-like family
Y61A9LA.8 Y61A9LA_68.A P W
Y65B4BL.5 Y65B4B_9.B P W
Y66H1A.5 Y66H1A.5 P W All gene names: Y66H1A.5; 4B180; CE22756; WBGene00022047; WP:CE22756
Y67A6A.1 Y67A6A.1 P W All gene names: Y67A6A.1; 1K406; CE20349; WBGene00013449; WP:CE20349
Y69E1A.1 Y69E1A.1 P W All gene names: Y69E1A.1; 4L712; CE22808; WBGene00013473; WP:CE22808
Y69E1A.2 Y69E1A.2 P W All gene names: Y69E1A.2; 4L715; CE22809; WBGene00013474; WP:CE22809
Y69H2.3 Y69H2.3 P W All gene names: Y69H2.3; Y69H2.3a.1; Y69H2.3a.2; Y69H2.3d.1; Y69H2.3d.2; 5T136; CE32543; CE32544; CE32545; CE32546; Q9U1T5_CAEEL; WBGene00013481; WP:CE32543; WP:CE32544; WP:CE32545; WP:CE32546
Y71H10A.2 Y71H10A.2 P W All gene names: Y71H10A.2; Y71H10A.2.1; Y71H10A.2.2; Y71H10A.2.3; Y71H10A.2.4; Y71H10A.2.5; CE20354; Q9TZL9_CAEEL; WBGene00022200; WP:CE20354; XD555
Y73F4A.1 Y73F4A.1 P W All gene names: Y73F4A.1; 4J808; CE20367; DMON2_CAEEL; WBGene00013514; WP:CE20367
Y73F8A.8 Y73F8A.G P W
Y73F8A.12 Y73F8A.K P W
Y39G10AR.6 Y74C10A_154.A P W
Y75B12B.2 Y75B12B.2 P W All gene names: cyn-7; cyp-7; Y75B12B.2; Y75B12B.2.1; Y75B12B.2.2; Y75B12B.2.3; 5P666; CE20371; CYP7_CAEEL; NM_074348; WBGene00000883; WP:CE20371 WormBase description: cyp-7 encodes a cyclophilin A isoform; while not tested peptidyl-prolyl isomerase activity in vitro, it is very similar to CYP-3 and closely resembles the prototypical CypA, and is therefore likely to be a member of the cytosolic CsA-binding cyclophilin subfamily; CYP-7 was required for embryonic viability in one set of mass RNAi assays. WormBase CDS description: Peptidyl-prolyl cis-trans isomerases
Y75B8A.23 Y75B8A.23 P W All gene names: Y75B8A.23; Y75B8A.Z; 3N339; CE23034; WBGene00013556; WP:CE23034
Y76A2A.1 Y76A2A.1 P W All gene names: tag-164; Y76A2A.1; 3O549; CE19270; WBGene00006509; WP:CE19270
Y76A2C.A Y76A2C.A P W
Y9D1A.1 Y9D1A.1 P W All gene names: Y9D1A.1; Y9D1A.C; 2H739; CE39996; WBGene00021186; WP:CE39996
ZC116.2 ZC116.2 P W All gene names: ZC116.2; 5N92; CE06565; CYC2_CAEEL; WBGene00013854; WP:CE06565 WormBase description: cytochrome c
ZC168.6 ZC168.6 P W All gene names: ZC168.6; 4L504; CE06572; SSPZC_CAEEL; WBGene00013858; WP:CE06572
ZC204.12 ZC204.12 P W All gene names: ZC204.12; 2B946; CE15106; WBGene00022562; WP:CE15106
ZC250.1 ZC250.1 P W All gene names: cyn-17; cyp-17; ZC250.1; 5G285; CE37686; NM_072121; WBGene00000893; WP:CE37686
ZC373.7 ZC373.7 P W All gene names: col-176; ZC373.7; CE02380; NM_077291; WBGene00000749; WP:CE02380; XK697 WormBase description: cuticular collagen
ZC376.8 ZC376.8 P W All gene names: ZC376.8; 5O661; CE38013; WBGene00013879; WP:CE38013
ZC477.1 ZC477.1 P W All gene names: ssq-3; ZC477.1; 4H875; CE28161; NM_068712; WBGene00006052; WP:CE28161
ZC477.7 ZC477.7 P W All gene names: ZC477.7; 4H874; CE05063; WBGene00022621; WP:CE05063
ZK1010.7 ZK1010.7 P W All gene names: col-97; ZK1010.7; 3O82; CE15507; NM_067299; WBGene00000672; WP:CE15507 WormBase description: collagen
ZK1128.3 ZK1128.3 P W All gene names: ZK1128.3; 3L206; CE01685; WBGene00014229; WP:CE01685; YS03_CAEEL
ZK1193.1 ZK1193.1 P W All gene names: col-19; ZK1193.1; CE05126; COL19_CAEEL; NM_075699; WBGene00000608; WP:CE05126; XB41; col19 WormBase description: col-19 encodes a member of the collagen superfamily containing collagen triple helix repeats (20 copies) that is required for normal structure of the alae; expressed during the L2-to-dauer and L4-to-adult molts with strongest expression in adult animals. WormBase CDS description: cuticular collagen
ZK1225.4 ZK1225.4 P W All gene names: ZK1225.4; 1N806; CE19343; WBGene00014238; WP:CE19343
ZK1225.6 ZK1225.6 P W All gene names: ssp-31; ZK1225.6; 1N811; CE19345; NM_060917; SSP31_CAEEL; WBGene00006048; WP:CE19345
ZK1236.7 ZK1236.7 P W All gene names: ZK1236.7; ZK1236.7.1; ZK1236.7.2; ZK1236.7.3; 3J530; CE29628; WBGene00022865; WP:CE29628; YO87_CAEEL
ZK1248.17 ZK1248.17 P W All gene names: ZK1248.17; 2G134; CE02901; WBGene00022884; WP:CE02901 WormBase description: major sperm protein
ZK1248.6 ZK1248.6 P W All gene names: msp-64; ZK1248.6; 2G100; NM_062748; WBGene00003457 WormBase description: msp-64 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. WormBase CDS description: Major sperm protein
ZK1251.6 ZK1251.6 P W All gene names: msp-76; ZK1251.6; 4K453; MSP10_CAEEL; NM_069321; WBGene00003463 WormBase description: msp-76 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. WormBase CDS description: major sperm protein (MSP1)
ZK1290.3 ZK1290.3 P W All gene names: rol-8; ZK1290.3; 2H835; CE29156; CE32085; COL6_CAEEL; NM_063181; NM_182112; WBGene00004398; WP:CE29156; WP:CE32085; col6 WormBase description: rol-8 encodes a collagen that is enriched in dauer larvae; mutations cause adults to become left-handed rollers.
ZK1290.8 ZK1290.8 P W All gene names: wrt-10; ZK1290.8; 2H824; CE02087; NM_063179; WBGene00006956; WP:CE02087 WormBase description: wrt-10 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a C-terminal region of low-complexity sequence; WRT-10 is expressed in both male and hermaphrodite intestine; the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-10 is required for normal growth to full size and locomotion; both of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
ZK1307.1 ZK1307.1 P W All gene names: ZK1307.1; ZK1307.1b.1; ZK1307.1b.2; 2J946; CE01690; CE35921; WBGene00014244; WP:CE01690; WP:CE35921; YS11_CAEEL
ZK1307.3 ZK1307.3 P W All gene names: ZK1307.3; 2J944b; CE01692; WBGene00014246; WP:CE01692; YS13_CAEEL
ZK1320.2 ZK1320.2 P W All gene names: ZK1320.2; ZK1320.2.1; ZK1320.2.2; 2J948; CE01700; WBGene00014252; WP:CE01700; YS22_CAEEL
ZK1320.3 ZK1320.3 P W All gene names: ZK1320.3; ZK1320.3.1; ZK1320.3.2; 2J950; CE01701; WBGene00014253; WP:CE01701; YS23_CAEEL
ZK265.2 ZK265.2 P W All gene names: col-63; ZK265.2; 1I820; CE15291; NM_059844; WBGene00000639; WP:CE15291 WormBase description: collagen
ZK265.3 ZK265.3 P W All gene names: ZK265.3; 1I819; CE15293; WBGene00013956; WP:CE15293
ZK354.11 ZK354.11 P W All gene names: msp-59; ZK354.11; 4G76; NM_068377; WBGene00003452 WormBase description: msp-59 encodes a member of the major sperm protein family. WormBase CDS description: major sperm protein (MSP-59)
ZK354.2 ZK354.2 P W All gene names: ZK354.2; 4G79; CE15314; CE31749; WBGene00022705; WP:CE15314; WP:CE31749 WormBase description: protein kinase
ZK354.4 ZK354.4 P W All gene names: msp-113; ZK354.4; 4G63; NM_068372; WBGene00003468 WormBase description: msp-113 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-113 has a C. briggsae homolog as detected by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; the msp-113 promoter region contains two conserved cis elements that are recognition sites for elt-1, a gene that encodes a homolog of the vertebrate GATA transcription factor family; this suggests that a MSP protein is a potential target for ELT-1 in the germ-line; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. WormBase CDS description: major sperm protein (MSP-113)
ZK354.5 ZK354.5 P W All gene names: msp-51; ZK354.5; 4G60; NM_068370; WBGene00003444 WormBase description: msp-51 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-51 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. WormBase CDS description: major sperm protein (MSP-51)
ZK354.6 ZK354.6 P W All gene names: ZK354.6; 4G62; CE15320; WBGene00022707; WP:CE15320 WormBase description: protein kinase
ZK354.8 ZK354.8 P W All gene names: ZK354.8; 4G70; CE15324; WBGene00022709; WP:CE15324 WormBase description: protein phosphatase
ZK455.1 ZK455.1 P W All gene names: aco-1; gei-22; ZK455.1; ZK455.1.1; ZK455.1.2; ACOC_CAEEL; CE03812; NM_077497; WBGene00000040; WP:CE03812; XL961 WormBase description: aco-1 encodes an aconitase that is homologous to mammalian iron regulatory protein-1 (IRP1); aco-1 activity is required for normal brood sizes and, under iron stress conditions, for normal lifespan and L4-to-adult growth rates; ACO-1 physically interacts with GEX-3; like IRP1, ACO-1 has aconitase activity and is post-translationally regulated by iron, but, unlike IRP1, it lacks RNA-binding activity; ACO-1 is predicted to be mitochondrial, and its mRNA levels appear to decrease in response to iron treatment. WormBase CDS description: iron-responsive element-binding like protein
ZK484.5 ZK484.5 P W All gene names: ZK484.5; 1G664; CE15345; WBGene00022751; WP:CE15345
ZK484.8 ZK484.8 P W All gene names: ZK484.8; ZK484.8.1; ZK484.8.2; 1G674; CE15351; WBGene00022754; WP:CE15351
ZK520.5 ZK520.5 P W All gene names: cyn-2; cyp-2; ZK520.5; ZK520.5.1; ZK520.5.2; 3O783; CE16730; CYP2_CAEEL; NM_067427; WBGene00000878; WP:CE16730 WormBase description: cyp-2 is a predicted member of the cytosolic CyclosporinA- binding cyclophilin family that is functional when expressed in E. coli. WormBase CDS description: Peptidyl-prolyl cis-trans isomerases
ZK525.2 ZK525.2 P W All gene names: aqp-11; ZK525.2; 3O765; CE33909; NM_067420; WBGene00000179; WP:CE33909
ZK546.3 ZK546.3 P W All gene names: ZK546.3; 2F231; CE02917; WBGene00022760; WP:CE02917 WormBase description: Major sperm protein
ZK546.6 ZK546.6 P W All gene names: msp-152; ZK546.6; 2F225; CE02920; MS152_CAEEL; NM_062500; WBGene00003470; WP:CE02920 WormBase description: msp-152 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. WormBase CDS description: Major sperm protein
ZK546.7 ZK546.7 P W All gene names: ZK546.7; 2F223; CE02921; WBGene00022763; WP:CE02921
ZK550.5 ZK550.5 P W All gene names: ZK550.5; 4S202; CE16736; WBGene00013999; WP:CE16736
ZK622.3 ZK622.3 P W All gene names: phi-40; ZK622.3; ZK622.3a.1; ZK622.3a.2; ZK622.3a.3; ZK622.3c.1; ZK622.3c.10; ZK622.3c.11; ZK622.3c.2; ZK622.3c.3; ZK622.3c.4; ZK622.3c.5; ZK622.3c.6; ZK622.3c.7; ZK622.3c.8; ZK622.3c.9; ZK622.3d.1; ZK622.3d.2; ZK622.3d.3; ZK622.3d.4; ZK622.3d.5; ZK622.3d.6; ZK622.3d.7; ZK622.3d.8; 2F570; CE29162; CE32290; CE33504; CE33505; WBGene00022781; WP:CE29162; WP:CE32290; WP:CE33504; WP:CE33505
ZK637.12 ZK637.12 P W All gene names: ZK637.12; 3K15; CE39882; WBGene00014029; WP:CE39882; YOUB_CAEEL
ZK669.3 ZK669.3 P W All gene names: ZK669.3; 2I235; CE01114; WBGene00014053; WP:CE01114; YO30_CAEEL
ZK686.4 ZK686.4 P W All gene names: ZK686.4; 3I860; CE00458; WBGene00022794; WP:CE00458; YO14_CAEEL
ZK742.3 ZK742.3 P W All gene names: ZK742.3; 5I288; CE07639; WBGene00022813; WP:CE07639
ZK792.2 ZK792.2 P W All gene names: inx-8; opu-8; ZK792.2; ZK792.2.1; ZK792.2.2; 4M439; CE27419; INX8_CAEEL; NM_069808; WBGene00002130; WP:CE27419 WormBase description: inx-8 encodes a predicted member of the innexin family that affects fertility; expressed in sheath cells. WormBase CDS description: Ogre family
ZK809.1 ZK809.1 P W All gene names: ZK809.1; 4M405; CE24741; WBGene00014085; WP:CE24741 WormBase description: protein-tyrosine phosphatase
ZK813.1 ZK813.1 P W All gene names: ZK813.1; ZK813.1.1; ZK813.1.2; CE33752; WBGene00022820; WP:CE33752; XE65
ZK813.2 ZK813.2 P W All gene names: ZK813.2; CE05111; WBGene00022821; WP:CE05111; XE61
ZK813.3 ZK813.3 P W All gene names: ZK813.3; CE29944; WBGene00022822; WP:CE29944; XE59
ZK896.5 ZK896.5 P W All gene names: ZK896.5; ZK896.5.1; ZK896.5.2; 4N642; CE28276; WBGene00014136; WP:CE28276
ZK930.4 ZK930.4 P W All gene names: ZK930.4; 2M199; CE06674; WBGene00014154; WP:CE06674
ZK945.1 ZK945.1 P W All gene names: ZK945.1; 2K387; CE01731; WBGene00014164; WP:CE01731; YS81_CAEEL WormBase description: esterase
ZK945.2 ZK945.2 P W All gene names: pas-7; ZK945.2; ZK945.2.1; ZK945.2.2; 2K388; CE36420; NM_063776; PSA3_CAEEL; WBGene00003928; WP:CE36420 WormBase description: proteasome component (A-type)
ZK945.7 ZK945.7 P W All gene names: ZK945.7; 2K398; CE01738; WBGene00014169; WP:CE01738; YS87_CAEEL