|Gene list file name:||Fox2005_S14-T2_unc-4_neuron-transcript_Synapse-Ass|
|Type of gene identifier:||Cosmid name|
|Description:||Fox et al 2005 Additional File 14/Table2: Summary of unc-4::GFP enriched and expressed (EGs) transcripts in selected categories. This file is an expanded version of Table 2 (see text) in which EGs are added to the list of enriched genes. Genes are organized as in Table 2 according to molecular function (KOG description, other description http://www.wormbase.org). Statistical rank is indicated for each enriched transcript and "EG" designates transcripts that are EGs.|
|Organism:||Caenorhabditis elegans (nematode)|
|Gene list type:||Experimental|
Gene name Source Gene ID Annotation Date Added by
C01B7.6 C01B7.6 P W All gene names: rpm-1; rpm-3; sad-3; sam-1; syd-3; C01B7.6; 5J282; CE06730; NM_072866; RPM1_CAEEL; WBGene00004457; WP:CE06730
C09D8.1 C09D8.1 P W All gene names: ptp-3; ptp-3A; ptp-3B; ypp-1; C09D8.1; 2L301; CE30244; CE30245; CE32793; LAR_CAEEL; WBGene00004215; WP:CE30244; WP:CE30245; WP:CE32793; YPP/1 WormBase description: ptp-3 encodes a receptor-like tyrosine phosphatase orthologous to the LAR (Leukocyte Common Antigen Related, OMIM:179590) subfamily of receptor-like tyrosine phosphatases that contain extracellular immunoglobulin-like and fibronectin type III domains and have been implicated in linking cell adhesion to intracellular phosphotyrosine levels; PTP-3 plays a role in gastrulation and epidermal development and functions partly redundantly with the VAB-1 Eph receptor and ephrins VAB-2 and EFN-4 to regulate embryonic morphogenesis; PTP-3 is expressed in many tissues during early embryogenesis, but expression later becomes localized to neuronal processes and epithelial adherens junctions.
C09H6.2 C09H6.2 P W All gene names: lin-10; C09H6.2; 1I686; CE15610; CE27060; LIN10_CAEEL; NM_059825; WBGene00002999; WP:CE15610; WP:CE27060 WormBase description: The lin-10 gene encodes a PDZ and PTB domain-containing protein that is homologous to mammalian Munc interacting proteins (Mint1, OMIM:602414) and is required for polarized protein localization; LIN-10 is required for proper localization of the LET-23 EGF receptor to the basolateral membrane of the vulval precursor cells and for proper postsynaptic localization of GLR-1, an AMPA-type glutamate receptor in interneurons; LIN-10 is detected in the cytoplasm, membrane, and at particularly high levels in the Golgi. WormBase CDS description: Phosphotyrosine interaction domain (PTB/PID)., PDZ domain (Also known as DHR or GLGF). (2 domains)
C16C2.4 C16C2.4 P W All gene names: C16C2.4; 1K290; CE15621; WBGene00007621; WP:CE15621
C18H9.7 C18H9.7 P W All gene names: rpy-1; C18H9.7; 2G994; CE01807; NM_062964; Q09485_CAEEL; WBGene00004507; WP:CE01807 WormBase description: rpy-1 is orthologous to the human gene 43KDA ACETYLCHOLINE RECEPTOR-ASSOCIATED PROTEIN (RAPSN; OMIM:601592), which when mutated leads to congenital myasthenic syndrome. WormBase CDS description: postsynaptic protein
F07B7.12 F07B7.12 P W All gene names: F07B7.12; 5J336; CE25842; WBGene00017190; WP:CE25842
F35D2.5 F35D2.5 P W All gene names: syd-1; F35D2.5; F35D2.5c.1; F35D2.5c.2; 2H876; CE33069; CE33391; CE33392; NM_063191; WBGene00006363; WP:CE33069; WP:CE33391; WP:CE33392 WormBase description: transcriptional activator HAP4 and regulatory domain of BCR and P85A
F59F5.6 F59F5.6 P W All gene names: syd-2; F59F5.6; CE03447; LIPA_CAEEL; NM_077367; WBGene00006364; WP:CE03447; XL168 WormBase description: syd-2 encodes alpha-liprin, a member of the liprin family of proteins that interact with LAR (leukocyte common antigen related)-type receptor tyrosine phosphatases (RPTPs) to facilitate clustering of RPTPs to focal adhesions; SYD-2 is required for establishing normal presynaptic density, and is expressed in all neurons and muscles; SYD-2 is required cell autonomously in neurons for differentiation of presynaptic active zones, where SYD-2 is localized. WormBase CDS description: liprin-alpha
K07F5.6 K07F5.6 P W All gene names: K07F5.6; 4K610; CE35586; WBGene00010634; WP:CE35586 WormBase description: protein-tyrosine phosphatase
Y54G11A.10 Y54G11A.10 P W All gene names: lin-7; Y54G11A.10; 2O634; CE28370; NM_064581; WBGene00002996; WP:CE28370 WormBase description: lin-7 encodes a protein that contains a PDZ domain and an L27 domain, two protein interaction domains that likely serve as organizational centers for large macromolecular complexes in polarized cells; LIN-7 is required for proper basolateral localization of the LET-23/EGF receptor in vulval epithelial cells, and along with LIN-2 and LIN-10, forms a protein complex that likely mediates this asymmetric localization with LIN-7 simultaneously binding to the C-terminus of LET-23 and an internal region of LIN-2; a LIN-7 translational reporter fusion indicates that LIN-7 is expressed at intestinal cell junctions; expression in vulval epithelial cells is detected only upon overexpression via heat shock, and reveals localization primarily at the lateral cell junctions of the vulval precursor cells P5.p and P6.p WormBase CDS description: PDZ domain (Also known as DHR or GLGF).