Fox et al 2005, S14/T2 Acetylcholine Receptor Sub, 17 genes

Gene list file name:Fox2005_S14-T2_unc-4_neuron-transcript_Acetylcholi
Type of gene identifier:Cosmid name
Description:Fox et al 2005 Additional File 14/Table2: Summary of unc-4::GFP enriched and expressed (EGs) transcripts in selected categories. This file is an expanded version of Table 2 (see text) in which EGs are added to the list of enriched genes. Genes are organized as in Table 2 according to molecular function (KOG description, other description http://www.wormbase.org). Statistical rank is indicated for each enriched transcript and "EG" designates transcripts that are EGs.  
Organism:Caenorhabditis elegans (nematode)
Gene list type:Experimental

Gene name             Source Gene ID          Annotation                                                  Date       Added by    

C02C2.3 C02C2.3 P W All gene names: cup-4; C02C2.3; 3I957; CE30416; CUP4_CAEEL; NM_066309; WBGene00000845; WP:CE30416 WormBase description: The primary phenotype of cup-4 animals is an accumulation of secreted GFP in the pseudocoelom, suggesting a decrease in, or the absence of, endocytosis in coelomocytes. WormBase CDS description: Acetylcholine receptor
C31H5.3 C31H5.3 P W All gene names: acr-19; C31H5.3; 1J608; CE30494; NM_060028; WBGene00000058; WP:CE30494 WormBase description: acr-19 encodes a predicted member of the alpha subunit family of nicotinic acetylcholine receptors. WormBase CDS description: nicotinic acetylcholine receptor
D2092.3 D2092.3 P W All gene names: acr-11; D2092.3; 1H198; CE09102; NM_059505; WBGene00000050; WP:CE09102 WormBase description: A homolog of an alpha type nicotinic acetylcholine receptor subunit involved in the mediation of fast synaptic transmission at neuromuscular junctions. WormBase CDS description: ligand-gated ionic channel protein
F21A3.7 F21A3.7 P W All gene names: F21A3.7; 5P990; CE36643; WBGene00008997; WP:CE36643
F21F3.5 F21F3.5 P W All gene names: tmr-2; unc-38; F21F3.5; 1F466; ACH5_CAEEL; CE24908; NM_059071; WBGene00006774; WP:CE24908 WormBase description: unc-38 encodes a nicotinic acetylcholine receptor (nAChR) alpha subunit; UNC-38 is required for normal locomotion and egg-laying, and functions as a subunit of a ligand-gated ion channel that likely mediates fast actions of acetylcholine at neuromuscular junctions and in the nervous system; when coexpressed with ACR-2, ACR-3, UNC-29, and LEV-1, non-alpha nAChR subunits, the resulting multimer can form levamisole-gated channels; UNC-38 is expressed postsynaptically in muscles and neurons where it colocalizes with TAX-6, and with ACR-8, ACR-12, and UNC-29, respectively. WormBase CDS description: ligand-gated ionic channel
F27B3.2 F27B3.2 P W All gene names: acr-21; F27B3.2; 3H673; CE39358; NM_066051; WBGene00000060; WP:CE39358 WormBase description: acr-21 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR); ACR-21 is a highly divergent member of the 'ACR-16' class of nAChR subunits, which includes ACR-7, ACR-9, ACR-10, ACR-11, ACR-14, ACR-15, ACR-16, and ACR-19, and is most closely related to the alpha-7 subunits of vertebrate nAChRs. WormBase CDS description: channel protein
F28F8.1 F28F8.1 P W All gene names: acr-18; F28F8.1; 5Q30; CE36645; NM_074467; WBGene00000057; WP:CE36645 WormBase description: acr-18 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR), predicted to be a ligand-gated ion channel regulating fast action of acetylcholine at neuromuscular junctions and in the nervous system; ACR-18 falls into the 'DEG-3' class of nAChR subunits, apparently unique to nematodes, which includes DEG-3, DES-2, ACR-5, ACR-17, ACR-20, and ACR-23. WormBase CDS description: acetylcholine receptor
K11G12.2 K11G12.2 P W All gene names: acr-2; K11G12.2; ACR2_CAEEL; CE07380; NM_076727; WBGene00000042; WP:CE07380; XH327 WormBase description: A homolog of a non-alpha type nicotinic acetylcholine receptor subunit that forms a functional channel when co-expressed with the unc-38 alpha subunit. WormBase CDS description: nicotinic acetylcholine receptor subunit
R01E6.4 R01E6.4 P W All gene names: acr-12; R01E6.4; CE29334; NM_077861; WBGene00000051; WP:CE29334; XO153 WormBase description: acr-12 encodes a nicotinic acetylcholine receptor (nAChR) alpha subunit that is a member of the ACR-8-like group of C. elegans nAChR subunits; as an nAChR subunit, ACR-12 is predicted to mediate fast excitatory neurotransmission, however loss of acr-12 activity via mutation or RNAi results in no obvious defects; ACR-12 copurifies with UNC-29 and LEV-1, suggesting that ACR-12 can form receptors with these two non-alpha AChR subunits; an ACR-12::GFP fusion protein is expressed exclusively in ventral cord motor neurons, including the D neurons; in vivo, ACR-12 colocalizes with some, but not all, UNC-38-containing postsynaptic receptor clusters, suggesting that ACR-12 contributes to only a subset of these receptor clusters. WormBase CDS description: acetylcholine receptor protein
R13A5.4 R13A5.4 P W All gene names: R13A5.4; 3I653; CE01376; WBGene00020048; WP:CE01376 WormBase description: ACHR
T05C12.2 T05C12.2 P W All gene names: acr-14; T05C12.2; 2I462; CE25099; NM_063315; WBGene00000053; WP:CE25099 WormBase description: acr-14 encodes a protein that contains neurotransmitter-gated ion-channel ligand-binding and transmembrane domains. WormBase CDS description: neuronal acetylcholine receptor protein
T08G11.5 T08G11.5 P W All gene names: tmr-4; unc-21; unc-29; unc-56; T08G11.5; 1J474; ACH2_CAEEL; CE13451; NM_059998; WBGene00006765; WP:CE13451 WormBase description: unc-29 encodes an non-alpha subunit of the nicotinic acetylcholine receptor (nAChR) superfamily; UNC-29 is required for normal locomotion and egg-laying, and functions as a subunit of a ligand-gated ion channel that likely mediates fast actions of acetylcholine at neuromuscular junctions and in the nervous system; when coexpressed with LEV-1, a non-alpha nAChR subunit, and UNC-38 or UNC-63, alpha AChR subunits, the resulting multimer can form levamisole-gated channels; UNC-29 is expressed in body wall muscle. WormBase CDS description: acetylcholine receptor, beta precursor
T14A8.1 T14A8.1 P W All gene names: des-5; ric-3; T14A8.1; 4I585; CE27448; NM_068898; WBGene00004363; WP:CE27448 WormBase description: The ric-3 gene encodes a novel, highly charged protein with two transmembrane domains and extensive coiled-coil domains; it is necessary for the function of at least four nicotinic acetylcholine receptors; specifically, it is needed for assembly or trafficking of the DEG-3 nicotinic acetylcholine receptor.
Y105E8A.7 Y105E8A.7 P W All gene names: eat-18; lev-10; Y105E8A.7; Y105E8E.F; 1O991; CE29845; CE33723; CE36334; CE37055; WBGene00001147; WBGene00002977; WP:CE29845; WP:CE33723; WP:CE36334; WP:CE37055 WormBase description: eat-18 encodes a predicted novel transmembrane protein; EAT-18 is required for proper nicotinic neurotransmission by the MC pharyngeal neuron and thus, for regulation of the pharyngeal pumping rate; EAT-18 is also required for alpha-bungarotoxin-binding to most or all pharyngeal nicotinic receptors; an EAT-18::GFP fusion protein is expressed in pharyngeal muscle, the M5 pharyngeal motor neuron, and five to six unidentified extrapharyngeal neurons; eat-18 interacts genetically with eat-2, which encodes a non-alpha nicotonic acetylcholine receptor subunit expressed in pharyngeal muscle and also required for proper regulation of the pharyngeal pumping rate.
Y110A7A.3 Y110A7A.3 P W All gene names: lev-7; tmr-3; unc-63; Y110A7A.3; 1F717; ACH6_CAEEL; CE30706; NM_059132; WBGene00006797; WP:CE30706 WormBase description: unc-63 encodes an alpha subunit of the nicotinic acetylcholine receptor (nAChR) superfamily; UNC-63 is required for normal locomotion, and functions as a subunit of a ligand-gated ion channel that likely mediates fast actions of acetylcholine at neuromuscular junctions and in the nervous system; when coexpressed with UNC-29 and LEV-1, non-alpha nAChR subunits, the resulting multimer can form levamisole-gated channels; UNC-63 is expressed in body wall muscles, vulval muscles, and a large number of neurons; UNC-63 is a member of the UNC-38-like group of nAChR subunits. WormBase CDS description: ion-channel protein
Y73B6BL.26 Y73B6BL.26 P W All gene names: Y73B6BL.26; 4H212; CE37587; WBGene00022247; WP:CE37587
ZC504.2 ZC504.2 P W All gene names: acr-8; ZC504.2; CE36679; NM_077344; WBGene00000047; WP:CE36679; XL33 WormBase description: acr-8 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR); ACR-8 falls into the 'ACR-8' class of nAChR subunits, which includes ACR-12 and ACR-13. WormBase CDS description: acetylcholine receptor protein