Chi et al. 2006, ST Up-reguulated in lin-35, 88 genes

Gene list file name:Chi2006_Gp4_Up_in_lin-35
Type of gene identifier:Cosmid name
Description:Chi et al 2006 Supplemental Table 88 genes up-regulated in lin-35 mutant.  
Organism:Caenorhabditis elegans (nematode)
Gene list type:Experimental

Gene name             Source Gene ID          Annotation                                                  Date       Added by    

B0336.3 B0336.3 P W All gene names: B0336.3; 3G803; CE29542; WBGene00015143; WP:CE29542
C06G3.7 C06G3.7 P W All gene names: TR-SE; trxr-1; C06G3.7; 4H779; CE34250; TRXR1_CAEEL; WBGene00015553; WP:CE34250 WormBase description: C06G3.7 encodes an homolog of the mammalian thioredoxin reductase isozymes TR1 and TR2; like its mammalian homologs, C06G3.7 has a TGA-encoded C-terminal penultimate selenocysteine (Sec) residue; labelling of C. elegans with selenium-75 demonstrates that TR-Se is the major naturally occurring selenoprotein in C. elegans, and computational analysis indicates that it is probably the only selenoprotein encoded by the genome; the 3'-untranslated region of this gene contains a selenocysteine insertion sequence that is functional in mammalian cell culture; by phylogenetic profiling, C06G3.7 protein is predicted to be mitochondrial. WormBase CDS description: pyridine nucleotide-disulphide oxidoreductase
C08F11.7 C08F11.7 P W All gene names: C08F11.7; 4O399; CE17384; WBGene00007454; WP:CE17384
C09H10.5 C09H10.5 P W All gene names: C09H10.5; 2L392; CE28534; WBGene00007499; WP:CE28534
C10H11.8 C10H11.8 P W All gene names: C10H11.8; 1F304; CE08097; WBGene00015697; WP:CE08097
C15H11.3 C15H11.3 P W All gene names: nxf-1; C15H11.3; 5O892; CE08180; NM_074166; NXF1_CAEEL; WBGene00003834; WP:CE08180 WormBase description: nxf-1 encodes a homolog of human TAP protein, a member of the NXF family of shuttling transport receptors for nuclear export of mRNA; binds RNA directly and its function has been shown to be conserved with the NXF family. WormBase CDS description: Leucine Rich Repeat (2 copies)
C15H9.4 C15H9.4 P W All gene names: C15H9.4; CE39558; Q18025_CAEEL; WBGene00015800; WP:CE39558; XG723
C17D12.7 C17D12.7 P W All gene names: C17D12.7; 1M196; CE23554; WBGene00007640; WP:CE23554
C17H12.2 C17H12.2 P W All gene names: C17H12.2; 4H552; CE16863; WBGene00015928; WP:CE16863
C26E6.3 C26E6.3 P W All gene names: C26E6.3; C26E6.3.1; C26E6.3.2; 3G35; CE32144; WBGene00016139; WP:CE32144 WormBase description: cell differentiation family, Rcd1-like
C34B7.4 C34B7.4 P W All gene names: C34B7.4; 1I909; CE27818; WBGene00007914; WP:CE27818
C34F6.2 C34F6.2 P W All gene names: col-178; C34F6.2; CE15671; NM_077468; WBGene00000751; WP:CE15671; XL819 WormBase description: collagen
C44B7.10 C44B7.10 P W All gene names: C44B7.10; C44B7.10.1; C44B7.10.2; C44B7.10.3; C44B7.10.4; 2H180; CE32326; WBGene00016630; WP:CE32326
C48B6.3 C48B6.3 P W All gene names: C48B6.3; C48B6.3.1; C48B6.3.2; 1H491; CE08805; WBGene00016741; WP:CE08805
C49A1.1 C49A1.1 P W All gene names: C49A1.1; 1O803; CE08827; WBGene00008184; WP:CE08827
C54G4.8 C54G4.8 P W All gene names: cyc-1; C54G4.8; C54G4.8.1; C54G4.8.2; 1I600; CE05514; NM_059806; WBGene00000869; WP:CE05514 WormBase description: cyc-1 encodes a component of complex III ( cytochrome c reductase) required for normal ATP production; reduction of ATP production by cyc-1(RNAi) decreases growth rate and body size, slows behavior, and increases lifespan; cyc-1 encodes a protein predicted by Eisenberg and coworkers, with 52% accuracy, to be mitochondrial WormBase CDS description: cytochrome C1, heme protein
C55C2.2 C55C2.2 P W All gene names: ssp-19; C55C2.2; 1D131; CE09025; NM_058599; SSP19_CAEEL; WBGene00006047; WP:CE09025
C56G2.15 C56G2.15 P W All gene names: C56G2.15; 3H456; CE01870; WBGene00016983; WP:CE01870
D2092.5 D2092.5 P W All gene names: D2092.5; 1H170; CE39714; WBGene00017066; WP:CE39714
DC2.5 DC2.5 P W All gene names: DC2.5; 5A688; CE36814; WBGene00017082; WP:CE36814 WormBase description: dehydrogenase
F08G5.4 F08G5.4 P W All gene names: col-130; F08G5.4; 4N192; CE05574; NM_069971; WBGene00000704; WP:CE05574 WormBase description: collagen
F11A3.2 F11A3.2 P W All gene names: F11A3.2; 5J997; CE05586; CE38501; WBGene00008670; WP:CE05586; WP:CE38501 WormBase description: guanine nucleotide exchange factor
F14F8.4 F14F8.4 P W All gene names: srz-103; F14F8.4; 5R156; CE37503; NM_074821; WBGene00008815; WP:CE37503
F22B5.2 F22B5.2 P W All gene names: eif-3.G; F22B5.2; 2I733; CE02197; IF34_CAEEL; NM_063377; WBGene00001230; WP:CE02197 WormBase description: eif-3.G encodes a homolog of eukaryotic translation initiation factor 3, subunit 4 that affects embryonic viability, fertility, and growth. WormBase CDS description: RNA binding protein
F26A1.13 F26A1.13 P W All gene names: F26A1.13; 3F936; CE02681; WBGene00017811; WP:CE02681
F26A1.14 F26A1.14 P W All gene names: F26A1.14; 3F938; CE02682; WBGene00017812; WP:CE02682 WormBase description: 2',3'-cyclic nucleotide 3'-phosphodiesterase
F26F2.7 F26F2.7 P W All gene names: F26F2.7; 5V59; CE19819; WBGene00009172; WP:CE19819
F31D4.2 F31D4.2 P W All gene names: F31D4.2; 5V312; CE15928; WBGene00009290; WP:CE15928
F33H1.4 F33H1.4 P W All gene names: F33H1.4; 2K469; CE02206; WBGene00009365; WP:CE02206
F36F12.2 F36F12.2 P W All gene names: F36F12.2; 5C570; CE17782; WBGene00018093; WP:CE17782
F42G9.1 F42G9.1 P W All gene names: F42G9.1; 3B403; CE07231; CE30788; PP2C1_CAEEL; WBGene00018362; WP:CE07231; WP:CE30788 WormBase description: Protein phosphatase
F45F2.11 F45F2.11 P W All gene names: F45F2.11; 5J0; CE10536; WBGene00018483; WP:CE10536
F48E8.2 F48E8.2 P W All gene names: F48E8.2; 3G555; CE39157; WBGene00018609; WP:CE39157
F53A2.5 F53A2.5 P W All gene names: dro-1; F53A2.5; 3O431; CE16097; NM_067349; WBGene00001092; WP:CE16097 WormBase description: Archael histone like
F53H1.4 F53H1.4 P W All gene names: F53H1.4; 4C91; CE31539; CE33651; CE33652; WBGene00018778; WP:CE31539; WP:CE33651; WP:CE33652
F53H2.3 F53H2.3 P W All gene names: F53H2.3; 5U866; CE19888; WBGene00010006; WP:CE19888
F54C1.3 F54C1.3 P W All gene names: mes-3; F54C1.3; 1F571; CE11046; CE36305; MES3_CAEEL; NM_059094; WBGene00003221; WP:CE11046; WP:CE36305 WormBase description: mes-3 encodes a novel protein with no discernible motifs; however, as a member of a Polycomb-like chromatin repressive complex with MES-2 and MES-6, MES-3 is required maternally for normal germline development and during larval development, for anteroposterior patterning; during germline development, the MES-2/MES-3/MES-6 complex is believed to be essential for maintaining repression of the X chromosome, and in transgenic animals, the complex is necessary for germline repression of repetitive transgenes; in axial patterning, the MES-2/MES-3/MES-6 complex is required in somatic tissues for maintaining homeotic gene repression, acting upstream of the Hox genes lin-39, mab-5, and egl-5, as well as the egl-5 target gene lin-32; MES-3 expression is detected in the nuclei of all cells during early embryogenesis, in some somatic cells and the germline precursors Z2 and Z3 during late embryogenesis and the L1 larval stage; in adults, MES-3 is expressed at highest levels in oocytes and germline nuclei in the proximal meiotic region with expression in the pachytene region negatively regulated by the RNA-binding protein GLD-1; MES-3 appears to be localized primarily to the nucleoplasm with some chromosomal association detectable during metaphase and early anaphase; in >24-cell-stage embryos, normal MES-3 levels and localization are dependent upon wild-type activity of MES-2 and MES-6
F55H2.5 F55H2.5 P W All gene names: F55H2.5; 3K601; CE00212; CY561_CAEEL; WBGene00010131; WP:CE00212 WormBase description: Cytochrome B561
F56C9.1 F56C9.1 P W All gene names: CEGLC-7B; Ce-glc-7beta; gsp-2; F56C9.1; F56C9.1.1; F56C9.1.2; 3I433; CE01319; GLC7B_CAEEL; WBGene00001748; WP:CE01319
F56D1.2 F56D1.2 P W All gene names: F56D1.2; CE01970; WBGene00018960; WP:CE01970; YSO2_CAEEL
F57B9.2 F57B9.2 P W All gene names: ntl-1; F57B9.2; 3I47; CE01337; NM_066115; WBGene00003824; WP:CE01337 WormBase description: let-711 was identified in separate screens for mutations that result either in maternal-effect spindle orientation in early embryos or in larval lethality; the maternal-effect let-711 mutation results in failure in centration and/or nuclear-centrosome rotation in early embryonic cleavages and suggests a role for let-711 in regulating microtubule catastrophe frequency; larval lethal mutations result in early or mid larval lethality; let-711 mutations can suppress cytokinesis defects produced by mutations in zyg-9, which encodes a homolog of the XMAP125 microtubule binding protein, and are enhanced by mutations in spn-1, which encodes a heterotrimeric G-protein alpha subunit also required for early embryonic cleavages; the molecular identity of let-711 is not yet known.
F57F5.5 F57F5.5 P W All gene names: kin-13; pkc-1; ttx-4; F57F5.5; F57F5.5.1; F57F5.5.2; 5M496; CE29092; KPC1B_CAEEL; NM_073613; WBGene00004032; WP:CE29092 WormBase description: pkc-1 encodes a serine/threonine protein kinase that is orthologous to mammalian protein kinase C epsilon (PRKCE), a member of the nPKC subgroup of the protein kinase C superfamily; together with UNC-13, PKC-1 may act downstream of goa-1 to modulate phorbol ester-induced stimulation of acetylcholine release at NMJs; PKC-1 positively regulates locomotion, and affects thermotaxis and chemotaxis together with kin-11; PKC-1 is required for regulating several behaviors including sensation of volatile and soluble compounds, osmolarity, and temperature (thermosensation); PKC-1 is also required for phorbolester-induced stimulation of acetylcholine release at neuromuscular junctions; PKC-1 localizes to the processes and cell bodies of approximately 75 sensory neurons and interneurons, and pkc-1 mRNA is detectable at varying levels during larval and adult stages. WormBase CDS description: Phorbol esters / diacylglycerol binding domain (2 domains), Protein kinase C terminal domain
H05L14.2 H05L14.2 P W All gene names: H05L14.2; 1I567; CE38199; WBGene00010367; WP:CE38199 WormBase description: Zinc finger, C3HC4 type (RING finger)
K03D10.3 K03D10.3 P W All gene names: K03D10.3; 1O717; CE23850; WBGene00010537; WP:CE23850 WormBase description: The K03D10.3 gene encodes a MYST acetyltransferase orthologous to the Drosophila MALES-ABSENT-ON-THE-FIRST (MOF) and CG1894 proteins, the human MOF protein, and the S. cerevisiae SAS2 protein.
K03H1.11 K03H1.11 P W All gene names: K03H1.11; 3L38; CE01026; WBGene00010546; WP:CE01026
K08C9.2 K08C9.2 P W All gene names: K08C9.2; 1M80; CE18859; WBGene00010651; WP:CE18859
K11D2.3 K11D2.3 P W All gene names: unc-101; K11D2.3; K11D2.3.1; K11D2.3.2; 1N105; AP1M_CAEEL; CE28050; NM_060773; WBGene00006829; WP:CE28050 WormBase description: unc-101 encodes an adaptin orthologous to the mu1-I subunit of adaptor protein complex 1 (AP-1) that is involved in motility, egg-laying, negative regulation of LET-23 / EGF-receptor signalling, and localization of the neuronal receptors ODR-10 and GLR-1; it is broadly expressed.
M03C11.4 M03C11.4 P W All gene names: M03C11.4; 3L496; CE03495; WBGene00010841; WP:CE03495
M110.4 M110.4 P W All gene names: ifg-1; M110.4; 2I511; CE02277; CE35745; WBGene00002066; WP:CE02277; WP:CE35745 WormBase description: ifg-1 encodes, by alternative splicing, two orthologs of the translational initiation factor eIF4 (eIF-4) gamma.
R06C1.2 R06C1.2 P W All gene names: R06C1.2; 1M510; CE23901; WBGene00011058; WP:CE23901 WormBase description: Polyprenyl synthetases
R06F6.2 R06F6.2 P W All gene names: R06F6.2; 2L78; CE01618; WBGene00011067; WP:CE01618; YRM2_CAEEL WormBase description: vacuolar biogenesis protein (pep5)
R08H2.3 R08H2.3 P W All gene names: srh-170; R08H2.3; 5P866; CE33156; NM_074422; WBGene00005386; WP:CE33156 WormBase description: G-protein coupled receptor, srh family
R144.7 R144.7 P W All gene names: larp-1; R144.7; 3G102; CE31582; CE39272; NM_065663; WBGene00020097; WP:CE31582; WP:CE39272
T07A5.2 T07A5.2 P W All gene names: T07A5.2; 3L404; CE36501; WBGene00011555; WP:CE36501; YRT2_CAEEL WormBase description: YK10 homolog
T07C4.8 T07C4.8 P W All gene names: ced-9; T07C4.8; 3L427; CE25104; CED9_CAEEL; NM_066883; WBGene00000423; WP:CE25104 WormBase description: ced-9 is required for control of programmed cell death during development; it encodes the only C. elegans homolog of BCL-2. WormBase CDS description: Apoptosis regulator proteins, Bcl-2 family
T23D8.1 T23D8.1 P W All gene names: mom-5; T23D8.1; 1K545; CE14048; NM_060234; WBGene00003397; WP:CE14048 WormBase description: Drosophila tissue polarity protein like
W05H9.3 W05H9.3 P W All gene names: W05H9.3; W05H9.3.1; W05H9.3.2; CE05038; WBGene00021050; WP:CE05038; XG873
W06E11.5 W06E11.5 P W All gene names: W06E11.5; 3B256; CE01430; CE26024; WBGene00021064; WP:CE01430; WP:CE26024; chic
W08G11.3 W08G11.3 P W All gene names: W08G11.3; 5Q849; CE39423; CE39424; WBGene00012347; WP:CE39423; WP:CE39424
Y102A5A.1 Y102A5A.1 P W All gene names: cand-1; Y102A5A.1; 5R293; CE20378; WBGene00013606; WP:CE20378
Y104H12D.3 Y104H12D.3 P W All gene names: Y104H12D.3; 4B953; CE31632; WBGene00022427; WP:CE31632
Y116A8C.36 Y116A8C.36 P W All gene names: itsn-1; tag-11; Y116A8C.36; 4S71; CE23342; NM_070636; WBGene00006405; WP:CE23342 WormBase description: tag-11/Y116A8C.36 encodes a homolog of human NCF1, which when mutated leads to chronic granulomatous disease (OMIM:306400).
Y19D10A.10 Y19D10A.10 P W All gene names: Y19D10A.10; 5C840; CE39813; WBGene00021225; WP:CE39813
Y34D9A.11 Y34D9A.11 P W All gene names: spp-23; Y34D9A.11; Y34D9A.G; 1B493; CE21539; WBGene00021335; WP:CE21539 WormBase description: 7TM chemoreceptor, spp family
Y38E10A.22 Y38E10A.22 P W All gene names: Y38E10A.22; 2M958; CE35653; WBGene00012600; WP:CE35653
Y39B6A.20 Y39B6A.20 P W All gene names: asp-1; Y39B6A.20; Y39B6A.20.1; Y39B6A.20.2; Y39B6B.G; 5T524; CE21681; NM_171587; WBGene00000214; WP:CE21681 WormBase description: asp-1 encodes a homolog of cathepsin D aspartic protease; it is transcribed exclusively in intestinal cells of the late embryo and early larvae and is not observed in older larvae or adults; ASP-1 is dispensable for neuronal degeneration. WormBase CDS description: peptidase (A1 pepsin family)
Y45G12C.7 Y45G12C.7 P W All gene names: srd-73; Y45G12C.7; 5D7; WBGene00021570 WormBase description: 7TM chemoreceptor, srd family
Y47G6A.10 Y47G6A.10 P W All gene names: phi-23; spg-7; Y47G6A.10; 1E45; CE34400; NM_058764; WBGene00004978; WP:CE34400 WormBase description: ATPase
Y49G5B.1 Y49G5B.1 P W All gene names: Y49G5B.1; Y49G5B.C; 5F707; CE22274; WBGene00021732; WP:CE22274
Y53C10A.3 Y53C10A.3 P W All gene names: Y53C10A.3; 1M562; CE22371; WBGene00013134; WP:CE22371 WormBase description: Y53C10A.3 encodes a paralog of HSF-1 that might regulate ubq-1, since ubq-1 has 5'-flanking sequences resembling heat shock regulatory elements, yet is uninduced by heat shock.
Y53G8AR.6 Y53G8AR.6 P W All gene names: Y53G8AR.6; 3E385; CE25422; WBGene00021813; WP:CE25422
Y54E10A.15 Y54E10A.15 P W All gene names: cdt-1; Y54E10A.15; 1D792; CE22447; NM_058725; NM_182086; WBGene00000413; WP:CE22447
Y54E10A.2 Y54E10A.2 P W All gene names: cogc-1; mig-30; Y54E10A.2; CE39656; WBGene00003258; WBGene00021825; WP:CE39656 WormBase description: cogc-1 encodes an ortholog of mammalian COG-1/ldlBp (OMIM:606973, mutated in congenital disorder of glycosylation type II), a subunit of lobe A of the conserved oligomeric Golgi complex (COGC); COGC-1 is required for normal gonadal distal tip cell migration, a process that also requires COGC-3 and six other orthologs of COGC subunits; COGC-1 is also required for normal vulval morphology, growth rate, ventral nerve cord fasciculation, and adult locomotion; COGC-1 has a predicted coiled-coil N-terminal domain; COGC-1 co-precipitates with COGC-3, and the amount of COGC-1 is lowered in a cogc-3 mutant, implying that these proteins not only bind one another but stabilize one another in vivo; in cogc-1 mutants, MIG-23 is abnormally localized and expressed within cells; in cogc-1 mutants, MIG-23's substrate MIG-17 is underglycosylated and fails to bind to the gonadal basement membrane, but is still secreted normally from muscle cells; cogc-1, cogc-3, and mig-17 null mutants do not enhance one another, indicating a shared genetic pathway; like other lobe A subunits in both C. elegans and S. cerevisiae, COGC-1 is strongly required for normal function, while lobe B subunits are only partially required in either worms or yeast.
Y55F3AR.3 Y55F3AR.3 P W All gene names: Y55F3AR.3; 4B840; CE35110; TCPQ_CAEEL; WBGene00021934; WP:CE35110
Y56A3A.31 Y56A3A.31 P W All gene names: Y56A3A.31; 3N79; CE22596; WBGene00013243; WP:CE22596
Y56A3A.6 Y56A3A.6 P W All gene names: Y56A3A.6; Y56A3A.6.1; Y56A3A.6.2; Y56A3A.F; 3M962; CE22577; WBGene00013227; WP:CE22577
Y61A9LA.8 Y61A9LA.8 P W All gene names: Y61A9LA.8; 5F42; CE31123; WBGene00022019; WP:CE31123
Y65A5A.3 Y65A5A.3 P W All gene names: Y65A5A.3; 4R183; CE22720; WBGene00013420; WP:CE22720
Y71H2AM.9 Y71H2AM.9 P W All gene names: Y71H2AM.9; 3D780; CE37454; WBGene00022174; WP:CE37454
Y87G2A.13 Y87G2A.13 P W All gene names: Y87G2A.13; Y87G2A.13.1; Y87G2A.13.2; Y87G2A.T; 1O194; CE37591; WBGene00013601; WP:CE37591
ZK484.4 ZK484.4 P W All gene names: ZK484.4; 1G648; CE27354; CE27355; WBGene00022750; WP:CE27354; WP:CE27355
ZK795.2 ZK795.2 P W All gene names: ZK795.2; 4N322; CE18463; WBGene00014082; WP:CE18463
ZK896.9 ZK896.9 P W All gene names: ZK896.9; 4N619; CE15465; WBGene00014139; WP:CE15465 WormBase description: CMP-sialic acid transporter