Blacque et al 2005, ST4 full list of X-Box-Contain, 1572 genes

Gene list file name:Blacque2005_ST4_1576-putative_X-Box
Type of gene identifier:Cosmid name
Description:Blacque et al 2005 S42 Full List of Putative X-Box-Containing Genes: Genes are ranked by X box score (homology to the consensus X box sequence). Only X boxes with scores >10.0 and within 1500 bp upstream of the gene start codons are included. Note also that only those genes with significant homology to a human gene are shown (Blast E-value < e.10).  
Organism:Caenorhabditis elegans (nematode)
Gene list type:Experimental

Gene name             Source Gene ID          Annotation                                                  Date       Added by    

AC3.5 AC3.5 P W All gene names: AC3.5; 5K873; CE36372; WBGene00007071; WP:CE36372; YQ02_CAEEL WormBase description: glutamyl aminopeptidase
B0019.1 B0019.1 P W All gene names: amx-2; B0019.1; 1N352; CE32294; NM_060835; WBGene00000138; WP:CE32294
B0024.11 B0024.11 P W All gene names: B0024.11; 5K798; CE05155; WBGene00007101; WP:CE05155; YQ4B_CAEEL WormBase description: Uncharacterized protein family UPF0024
B0024.8 B0024.8 P W All gene names: B0024.8; 5K780; CE25738; WBGene00007098; WP:CE25738
B0035.10 B0035.10 P W All gene names: his-45; B0035.10; 4M91; NM_069733; WBGene00001919; his 9 WormBase description: his-45 encodes an H3 histone. WormBase CDS description: histone H3
B0035.12 B0035.12 P W All gene names: B0035.12; B0035.12.1; B0035.12.2; 4M96; CE05167; WBGene00007111; WP:CE05167 WormBase description: polyadenylate-binding protein like
B0035.5 B0035.5 P W All gene names: B0035.5; B0035.5.1; B0035.5.2; 4M83; CE05163; G6PD_CAEEL; WBGene00007108; WP:CE05163 WormBase description: B0035.5 is orthologous to the human gene GLUCOSE-6-PHOSPHATE DEHYDROGENASE (G6PD; OMIM:305900), which when mutated leads to disease. WormBase CDS description: glucose-6-phosphate-1-dehydrogenase
B0198.1 B0198.1 P W All gene names: tsp-20; B0198.1; CE26461; NM_077613; WBGene00006646; WP:CE26461; XM652 WormBase description: tetraspanin
B0205.10 B0205.10 P W All gene names: B0205.10; B0205.10.1; B0205.10.2; 1L285; CE17324; WBGene00015024; WP:CE17324
B0205.7 B0205.7 P W All gene names: kin-3; B0205.7; B0205.7.1; B0205.7.2; 1L311; CE17321; CSK2A_CAEEL; NM_060410; WBGene00002191; WP:CE17321 WormBase description: kin-3 encodes an ortholog of the catalytic subunit of casein kinase II alpha, which in Drosophila and mammals is required for normal circadian rhythms, and which directly phosphorylates the Drosophila PERIOD protein (which itself regulates circadian rhythms); by analogy, KIN-3 might be expected to help regulate heterochronic functions dependent on such proteins as LIN-42. WormBase CDS description: casein kinase
B0213.14 B0213.14 P W All gene names: cyp-34A8; B0213.14; 5E444; CE16784; NM_071701; WBGene00015043; WP:CE16784 WormBase description: cytochrome P450
B0218.3 B0218.3 P W All gene names: pmk-1; B0218.3; 4I913; CE06686; NM_068964; PMK1_CAEEL; WBGene00004055; WP:CE06686 WormBase description: pmk-1 encodes a mitogen-activated protein kinase (MAPK), orthologous to human p38 MAPK (OMIM:600289), that is required for eliciting gonadal programmed cell death in response to Salmonella enterica infection; PMK-1 lies upstream of CED-9, a negative regulator of apoptosis, in the programmed cell death pathway. WormBase CDS description: ser/thr kinases
B0218.6 B0218.6 P W All gene names: clec-51; B0218.6; 4I928; CE06689; WBGene00015050; WP:CE06689 WormBase description: 7TM chemoreceptor, clec family
B0218.8 B0218.8 P W All gene names: clec-52; B0218.8; 4I932; CE06691; WBGene00015052; WP:CE06691 WormBase description: 7TM chemoreceptor, clec family
B0272.1 B0272.1 P W All gene names: tbb-4; B0272.1; CE00850; NM_077184; TBB4_CAEEL; WBGene00006538; WP:CE00850; XK54 WormBase description: tubulin beta chain
B0273.2 B0273.2 P W All gene names: puf-7; B0273.2; B0273.2.1; B0273.2.2; 4G253; CE16788; NM_068419; WBGene00004243; WP:CE16788 WormBase description: puf-7 encodes a protein 97% identical to PUF-6 and functions redundantly with the other PUF genes, fbf-1, fbf-2, puf-6, and puf-8, during primordial germ cell development, based on combinatorial RNAi; interacts with NOS-2 in yeast two-hybrid screens.
B0281.3 B0281.3 P W All gene names: B0281.3; 2C595; CE07714; WBGene00015110; WP:CE07714
B0285.10 B0285.10 P W All gene names: ckb-3; B0285.10; 3F461; CE00649; KICB3_CAEEL; NM_065480; WBGene00000513; WP:CE00649 WormBase description: ckb-3 encodes a putative choline kinase; CKB-1 through CKB-4 comprise a related group ('B') of choline kinases. WormBase CDS description: choline kinase
B0285.8 B0285.8 P W All gene names: ckb-1; B0285.8; 3F455; CE33590; KICB1_CAEEL; NM_065478; WBGene00000511; WP:CE33590 WormBase description: ckb-1 encodes a putative choline kinase; CKB-1 through CKB-4 comprise a related group ('B') of choline kinases. WormBase CDS description: choline kinase
B0331.1 B0331.1 P W All gene names: cyp-29A4; B0331.1; 5K137; CE15551; NM_073089; WBGene00007140; WP:CE15551 WormBase description: cytochrome P450
B0334.2 B0334.2 P W All gene names: twk-5; B0334.2; 2L774; CE36421; CE37874; WBGene00006660; WP:CE36421; WP:CE37874 WormBase description: twk-5 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; as loss of TWK-5 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of TWK-5 in C. elegans development and/or behavior is not yet known; TWK-5 may, however, function redundantly with other TWK channels; the TWK-5 expression pattern is not yet known.
B0334.8 B0334.8 P W All gene names: age-1; daf-23; B0334.8; 2L810; AGE1_CAEEL; CE23506; NM_064061; WBGene00000090; WP:CE23506 WormBase description: age-1 encodes the C. elegans ortholog of the phosphoinositide 3-kinase (PI3K) p110 catalytic subunit; AGE-1, supplied maternally and embryonically, is a central component of the C. elegans insulin-like signaling pathway, lying downstream of the DAF-2/insulin receptor and upstream of both the PDK-1 and AKT-1/AKT-2 kinases and the DAF-16 forkhead type transcription factor, whose negative regulation is the key output of the insulin signaling pathway; in accordance with its role in insulin signaling, AGE-1 activity is required for regulation of metabolism, life span, dauer formation, stress resistance, salt chemotaxis learning, fertility, and embryonic development; although the age-1 expression pattern has not yet been reported, ectopic expression studies indicate that pan-neuronal age-1 expression is sufficient to rescue life-span defects, while neuronal, intestinal, or muscle expression can partially rescue dauer formation, and neuronal or muscle expression can rescue metabolic defects. WormBase CDS description: phosphatidylinositol 3-kinase
B0336.8 B0336.8 P W All gene names: lgg-3; B0336.8; 3G786; CE00776; NM_065827; WBGene00002982; WP:CE00776 WormBase description: lgg-3 encodes a hydrophilic protein that is orthologous to Saccharomyces cerevisiae autophagy protein Apg12p; by homology, LGG-3 is predicted to function as a modifier protein required for a protein conjugation system essential for autophagy; in the context of this conjugation system, LGG-3 is predicted to interact with Apg7p and Apg5p homologs (encoded by M7.5 and Y71G12B.12a, respectively) to effect bulk degradation of cytoplasmic components under conditions of starvation or cellular remodeling; free LGG-3 is predicted to localize to the cytoplasm, while LGG-3 conjugated to the Apg5p homolog is predicted to associate with membrane compartments; loss of lgg-3 activity via large-scale RNAi screens results in no obvious developmental or behavioral abnormalities.
B0393.5 B0393.5 P W All gene names: B0393.5; 3F865; CE00858; WBGene00007170; WP:CE00858 WormBase description: EGF-like aspartic acid and asparagine hydroxylation sites
B0395.3 B0395.3 P W All gene names: B0395.3; B0395.3.1; B0395.3.2; CE02944; WBGene00007175; WP:CE02944; XQ650 WormBase description: B0395.3 is orthologous to the human gene CHOLINE ACETYLTRANSFERASE ISOFORM R (CHAT; OMIM:118490), which when mutated leads to disease. WormBase CDS description: choline O-acetyltransferase
B0416.1 B0416.1 P W All gene names: B0416.1; CE19663; WBGene00015177; WP:CE19663; XJ927; YT41_CAEEL
B0432.9 B0432.9 P W All gene names: B0432.9; 2A570; CE34245; WBGene00015190; WP:CE34245 WormBase description: zinc finger protein
B0464.2 B0464.2 P W All gene names: B0464.2; 3K585; CE20456; WBGene00007184; WP:CE20456; YKD1_CAEEL WormBase description: TPR Domain
B0491.2 B0491.2 P W All gene names: rol-5; sqt-1; B0491.2; B0491.2.1; B0491.2.2; 2L626; CE02104; NM_064020; Rol; SQT1_CAEEL; WBGene00005016; WP:CE02104 WormBase description: sqt-1 encodes a cuticle collagen; during larval and adult development, sqt-1 activity is required, likely redundantly, for normal cuticle, and hence organismal, morphology; sqt-1 mRNA abundance oscillates during larval development, peaking at one point during each larval stage and peaking again in adults; sqt-1 transcripts are also detected in animals at the L1-L2d molt; in the temporally distinct waves of collagen gene expression that occur during larval development, sqt-1 mRNA appears to be synthesized during the second, or intermediate, stage, just very slightly earlier than sqt-3/col-1 and dpy-13; SQT-1 protein is detected in cuticle extracts from L2, L3, and L4 larvae, and from adults, but is not detected in extracts from L1 or dauer larvae; sqt-1 interacts genetically with a number of genes also required for normal cuticle and organismal morphology, e.g., rol-6 and lon-3, which also encode cuticular collagens. WormBase CDS description: cuticle collagen SQT-1
B0495.7 B0495.7 P W All gene names: B0495.7; B0495.7.1; B0495.7.2; 2H992; CE29550; WBGene00015206; WP:CE29550; YP67_CAEEL
B0507.1 B0507.1 P W All gene names: B0507.1; 5J259; CE28815; Q22886_CAEEL; WBGene00015218; WP:CE28815
B0511.13 B0511.13 P W All gene names: B0511.13; 1L210; CE32106; WBGene00015238; WP:CE32106
B0524.1 B0524.1 P W All gene names: B0524.1; B0524.F; 3C997; CE39203; WBGene00015240; WP:CE39203
B0524.2 B0524.2 P W All gene names: B0524.2; B0524.E; 3C989; CE39204; WBGene00015241; WP:CE39204
B0563.2 B0563.2 P W All gene names: tsp-11; B0563.2; CE35212; NM_077145; WBGene00006637; WP:CE35212; XJ781 WormBase description: transpanin
C01B12.1 C01B12.1 P W All gene names: sqt-2; C01B12.1; 2A315; CE07789; NM_061234; WBGene00005017; WP:CE07789 WormBase description: sqt-2 encodes a collagen required for normal alae formation and body morphology; sqt-2 mutants exhibit a slightly dumpy phenotype and the bodies of mutants are helically twisted. WormBase CDS description: cuticular collagen
C01G5.5 C01G5.5 P W All gene names: C01G5.5; 4H291; CE06751; WBGene00015307; WP:CE06751 WormBase description: aldehyde reductase
C01G6.5 C01G6.5 P W All gene names: C01G6.5; 2J566; CE00867; WBGene00007227; WP:CE00867; YKI5_CAEEL WormBase description: Forkhead-associated (FHA) domain
C01H6.1 C01H6.1 P W All gene names: col-61; C01H6.1; 1H778; CE05184; NM_059634; WBGene00000637; WP:CE05184 WormBase description: collagen
C01H6.4 C01H6.4 P W All gene names: C01H6.4; 1H787; CE30237; WBGene00007254; WP:CE30237 WormBase description: Flavin-binding monooxygenase-like
C01H6.7 C01H6.7 P W All gene names: tag-298; C01H6.7; 1H803; CE05190; Q17581_CAEEL; WBGene00007256; WP:CE05190 WormBase description: Bromodomain
C02B10.3 C02B10.3 P W All gene names: C02B10.3; C02B10.3.1; C02B10.3.2; 4F858; CE29018; WBGene00015328; WP:CE29018; YC2BA_CAEEL
C02C6.3 C02C6.3 P W All gene names: C02C6.3; CE29169; CE39214; WBGene00007261; WP:CE29169; WP:CE39214; XQ166 WormBase description: Leucine Rich Repeat (2 copies)
C02D5.1 C02D5.1 P W All gene names: C02D5.1; 3J649; CE24778; IVD_CAEEL; WBGene00015335; WP:CE24778 WormBase description: Isovaleryl-CoA dehydrogenase
C02G6.2 C02G6.2 P W All gene names: C02G6.2; 5G353; CE35214; WBGene00015360; WP:CE35214 WormBase description: peptidase
C02H7.1 C02H7.1 P W All gene names: C02H7.1; CE06757; WBGene00015363; WP:CE06757; XB385
C03A7.4 C03A7.4 P W All gene names: pqn-5; C03A7.4; 5F633; CE07862; NM_071981; O16500_CAEEL; WBGene00004099; WP:CE07862 WormBase description: The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
C03C10.3 C03C10.3 P W All gene names: rnr-2; C03C10.3; C03C10.3.1; C03C10.3.2; C03C10.3.3; 3F184; CE00874; NM_065420; RIR2_CAEEL; WBGene00004392; WP:CE00874 WormBase description: Ribonuclease-diphosphate reductase M2
C03D6.3 C03D6.3 P W All gene names: cel-1; C03D6.3; 1K243; CE05197; CE32300; MCE1_CAEEL; NM_060168; WBGene00000466; WP:CE05197; WP:CE32300 WormBase description: cel-1 encodes a mRNA capping enzyme, with a N-terminal region with RNA triphosphatase activity and a C-terminal region containing motifs found in yeast and vaccinia virus capping enzyme guanylytransferases; cel-1 is required for embryonic viability, body morphology, and vulval development.
C03D6.5 C03D6.5 P W All gene names: C03D6.5; 1K235; CE36095; WBGene00007277; WP:CE36095 WormBase description: anti-silencing protein
C03D6.8 C03D6.8 P W All gene names: rpl-24.2; C03D6.8; C03D6.8.1; C03D6.8.2; 1K245; CE05202; NM_060171; RLP24_CAEEL; WBGene00004437; WP:CE05202 WormBase description: rpl-24.2 encodes a large ribosomal subunit L24 protein paralog; its orthologs include ribosomal protein L30 isologs from mammals and 'Ribosomal Like Protein 24' (Rlp24p) from S. cerevisiae; it therefore appears to actually represent an ancient paralogy between two varieties of eukaryotic L24 protein. WormBase CDS description: ribosomal protein
C03F11.3 C03F11.3 P W All gene names: C03F11.3; CE37606; WBGene00015389; WP:CE37606; XG16; YX13_CAEEL WormBase description: glycoprotein
C03G6.12 C03G6.12 P W All gene names: nhr-149; C03G6.12; 5H828; CE07886; WBGene00015397; WP:CE07886 WormBase description: C4-type zinc finger protein
C03G6.19 C03G6.19 P W All gene names: srp-6; C03G6.19; 5H866; CE27579; NM_072489; WBGene00005647; WP:CE27579 WormBase description: srp-6 encodes a functional serpin (serine protease inhibitor) WormBase CDS description: serine protease inhibitor
C03G6.8 C03G6.8 P W All gene names: nhr-147; C03G6.8; 5H827; CE07882; WBGene00015395; WP:CE07882
C03H5.4 C03H5.4 P W All gene names: C03H5.4; 2A667; CE07897; WBGene00015406; WP:CE07897 WormBase description: phospholipase
C04A11.3 C04A11.3 P W All gene names: tag-334; C04A11.3; CE07905; WBGene00007287; WP:CE07905; XO299 WormBase description: serine/threonine kinase
C04C3.3 C04C3.3 P W All gene names: C04C3.3; C04C3.3.1; C04C3.3.2; 4E167; CE27647; ODPB_CAEEL; WBGene00015413; WP:CE27647 WormBase description: pyruvate dehydrogenase
C04C3.5 C04C3.5 P W All gene names: dyf-3; C04C3.5; 4E162; CE16811; CE38264; CE38265; O44450_CAEEL; WBGene00001119; WBGene00015415; WP:CE16811; WP:CE38264; WP:CE38265 WormBase description: dyf-3 encodes an ortholog of zebrafish cluap1 (also qilin, and like PKD2 required to suppress kidney cysts) and human clusterin-associated protein 1 (CLUAP1); DYF-3 is predicted to have two coiled-coil domains; DYF-3 is required for normal assembly of middle and distal ciliary segments, with dyf-3 mutants showing truncated sensory cilia; DYF-3 is required cell-autonomously for dye uptake; dyf-3 is expressed in amphid, phasmid, and IL2 sensory neurons; dyf-3 expression requires DAF-19.
C04F1.2 C04F1.2 P W All gene names: C04F1.2; 1G281; WBGene00015443
C04F1.3 C04F1.3 P W All gene names: lim-7; C04F1.3; 1G301; CE17366; NM_059267; Q94160_CAEEL; WBGene00002989; WP:CE17366 WormBase description: homeobox protein
C04F12.1 C04F12.1 P W All gene names: C04F12.1; 1K250; CE19674; WBGene00007297; WP:CE19674
C04F5.7 C04F5.7 P W All gene names: ugt-63; C04F5.7; 5F584; CE19671; WBGene00015449; WP:CE19671 WormBase description: 7TM chemoreceptor, ugt family
C04H5.1 C04H5.1 P W All gene names: C04H5.1; 2O821; CE15587; TR112_CAEEL; WBGene00007312; WP:CE15587
C05B10.1 C05B10.1 P W All gene names: lip-1; C05B10.1; 4H607; CE31151; NM_068652; WBGene00003043; WP:CE31151 WormBase description: lip-1 encodes a mitogen-activated protein (MAP) kinase phosphatase homologous to the vertebrate dual specificity phosphatase MKP-3; during development, LIP-1 negatively regulates MAP kinase activity to control the extent of germline proliferation and oocyte meiotic cell cycle progression; lip-1 activity is also required redundantly with dep-1 to negatively regulate MAPK signaling during vulval induction; in addition, lip-1 is required for normal embryonic development; lip-1 expression begins during embryogenesis and continues through adulthood; expression is seen in most somatic cells and in germ cells of the pachytene region, transition zone and proximal-most region of the mitotic zone; in the pachytene region, LIP-1 is associated with the plasma membrane; in early L3 larvae, LIP-1 expression increases in secondary vulval precursor cells in a lin-12/Notch-dependent manner, suggesting that lip-1 may be a direct downstream target of lin-12-mediated signaling; interaction with the Notch pathway is further demonstrated by chromatin immunoprecipitation experiments showing that, in the germline, the lip-1 promoter region coprecipitates with LAG-3; germline lip-1 mRNA accumulation is negatively regulated by the FBF proteins (FBF-1 and FBF-2) that bind to the lip-1 3'UTR. WormBase CDS description: protein-tyrosine phosphatase
C05C8.3 C05C8.3 P W All gene names: dao-1; fkb-3; C05C8.3; 5H707; CE07921; NM_072434; WBGene00001428; WP:CE07921 WormBase description: fkb-3 encodes a peptidylprolyl cis/trans isomerase homologous to mammalian FK506 immunosuppressant-binding protein 9; FKB-3 expression is positively regulated by signaling through the DAF-2 insulin receptor-like pathway and the activity of the DAF-16 fork-head transcription factor suggesting that FKB-3 could play a role in metabolism and longevity; however, as loss of FKB-3 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of FKB-3 in C. elegans development and/or behavior is not yet known; FKB-3 contains a predicted endoplasmic reticulum (ER) retention sequence and is thus proposed to localize to the ER. WormBase CDS description: FKBP-binding protein
C05D2.3 C05D2.3 P W All gene names: C05D2.3; 3G707; CE29022; WBGene00015467; WP:CE29022 WormBase description: C05D2.3 generally resembles aromatic-L-amino-acid/L-histidine decarboxylases; however, its predicted protein sequence lacks six residues critical for AADC function; C05D2.3 is dispensable in mass RNAi assays. WormBase CDS description: aromatic-L-amino-acid decarboxylase
C05D2.4 C05D2.4 P W All gene names: bas-1; C05D2.4; 3G703; CE01141; CE37081; O45137_CAEEL; WBGene00000239; WP:CE01141; WP:CE37081 WormBase description: bas-1 encodes a serotonin- and dopamine-synthetic aromatic amino acid decarboxylase (AAADC) that is required for the synthesis of serotonin from 5-hydroxytryptophan in vivo; mutations of bas-1 impair the turning step in male mating, the migration of AVM, SDQR, ALM, and BDU neurons during development. WormBase CDS description: aromatic-L-amino-acid decarboxylase
C05D9.1 C05D9.1 P W All gene names: snx-1; C05D9.1; C05D9.1.1; C05D9.1.2; C05D9.1.3; CE07927; NM_075815; Q9GYJ9_CAEEL; SNX1; WBGene00004927; WP:CE07927; XB751
C05G5.1 C05G5.1 P W All gene names: C05G5.1; CE05224; WBGene00007347; WP:CE05224; XP354
C06A12.4 C06A12.4 P W All gene names: gcy-27; C06A12.4; 4S376; CE39668; NM_070709; WBGene00001550; WP:CE39668 WormBase description: guanylate cyclase (2 domains)
C06C6.4 C06C6.4 P W All gene names: nhr-63; C06C6.4; 5Q483; CE28202; NM_171557; WBGene00003653; WP:CE28202 WormBase description: Zinc finger, C4 type (two domains)
C06E4.4 C06E4.4 P W All gene names: C06E4.4; 4I17; CE03952; WBGene00015533; WP:CE03952 WormBase description: dehydrogenase
C06G1.5 C06G1.5 P W All gene names: C06G1.5; CE37187; WBGene00015548; WP:CE37187; XR254 WormBase description: protein phosphatase PP2A
C06G3.2 C06G3.2 P W All gene names: klp-18; C06G3.2; 4H807; CE07978; NM_068692; WBGene00002228; WP:CE07978 WormBase description: klp-18 encodes a kinesin motor protein whose motor domain is most similar to that of the Xenopus and human klp2 proteins; loss of klp-18 activity via RNAi indicates that KLP-18 is required for the assembly of a disordered array of acentrosomal (female meiotic) microtubules into an organized, functional, bipolar spindle; in addition, KLP-18 may also play a role in cortex dynamics during post-meiotic development; antibody staining indicates that during meiosis and mitosis (early embryonic) KLP-18 localizes to: 1) spindles, and especially spindle poles, during prometaphase, metaphase, and early anaphase, and 2) the interzone during late anaphase and telophase; in early embryos, KLP-18 is also seen around the nucleus and cell cortex at sites of cell-cell contact; KLP-18 expression in later embryos and larvae is confined to the germ line which, in adults, stains brightly in both distal and proximal regions. WormBase CDS description: kinesin-like protein
C06H2.3 C06H2.3 P W All gene names: C06H2.3; 5L609; CE05235; WBGene00007387; WP:CE05235 WormBase description: Acetyltransferase (GNAT) family
C07A9.11 C07A9.11 P W All gene names: ncx-7; C07A9.11; 3K806; CE39219; NCX7_CAEEL; NM_066746; WBGene00003572; WP:CE39219 WormBase description: Na/Ca, K antiporter
C07D10.4 C07D10.4 P W All gene names: nas-7; C07D10.4; 2H690; CE34663; NAS7_CAEEL; NM_063151; WBGene00003526; WP:CE34663 WormBase description: Zinc metalloprotease
C07E3.4 C07E3.4 P W All gene names: C07E3.4; 2K653; CE02120; WBGene00007415; WP:CE02120 WormBase description: Protein-tyrosine phosphatase
C07H6.2 C07H6.2 P W All gene names: C07H6.2; 3I609; CE00756; WBGene00015579; WP:CE00756
C08F8.4 C08F8.4 P W All gene names: C08F8.4; 4L922; CE05251; WBGene00007446; WP:CE05251
C08F8.7 C08F8.7 P W All gene names: rap-3; rrp-2; C08F8.7; 4L941; CE08025; NM_069694; WBGene00004309; WP:CE08025 WormBase description: RAS-related protein
C08F8.8 C08F8.8 P W All gene names: nhr-67; C08F8.8; 4L939; CE18491; NHR67_CAEEL; NM_069693; WBGene00003657; WP:CE18491 WormBase description: nuclear hormone receptor
C08G5.4 C08G5.4 P W All gene names: snt-6; C08G5.4; 2B30; CE34672; NM_061401; WBGene00004926; WP:CE34672
C08H9.10 C08H9.10 P W All gene names: C08H9.10; 2K142; CE02995; WBGene00007469; WP:CE02995 WormBase description: chitinase
C08H9.2 C08H9.2 P W All gene names: C08H9.2; 2K178; CE23530; WBGene00007463; WP:CE23530 WormBase description: high-density lipoprotein-binding protein
C08H9.3 C08H9.3 P W All gene names: C08H9.3; 2K174; ALG8_CAEEL; CE36914; CE37608; WBGene00007464; WP:CE36914; WP:CE37608 WormBase description: glucosyltransferase
C09B9.4 C09B9.4 P W All gene names: C09B9.4; 4F796; CE06796; WBGene00015629; WP:CE06796 WormBase description: ser/thr protein kinase
C09G12.1 C09G12.1 P W All gene names: C09G12.1; 4E263; CE16835; WBGene00015651; WP:CE16835 WormBase description: C09G12.1 encodes a paired-like homeodomain protein of the K50 class, which has no obvious function in mass RNAi assays. WormBase CDS description: homeobox protein
C09G5.2 C09G5.2 P W All gene names: C09G5.2; 2K992; CE15608; WBGene00007488; WP:CE15608; YQ32_CAEEL WormBase description: C09G5.2 encodes an ortholog of S. cerevisiae DPH2/YKL191W and human DPH2L2 (OMIM:603456); C09G5.2 is a putative protein component of diphtamide synthesis; C09G5.2 has no obvious function in mass RNAi assays. WormBase CDS description: Diphthamide biosynthesis protein (diptheria resistance protein)
C09H10.2 C09H10.2 P W All gene names: rpl-41; C09H10.2; C09H10.2.1; C09H10.2.2; C09H10.2.3; 2L388; CE02131; NM_063974; RL44_CAEEL; WBGene00004454; WP:CE02131 WormBase description: rpl-41 encodes a large ribosomal subunit L41 protein; by homology, RPL-41 is predicted to function in protein biosynthesis. WormBase CDS description: 60S ribosomal protein
C10A4.8 C10A4.8 P W All gene names: C10A4.8; CE35391; WBGene00015669; WP:CE35391; XI30 WormBase description: Zinc finger protein
C10C5.1 C10C5.1 P W All gene names: C10C5.1; 4K122; CE03009; WBGene00007505; WP:CE03009
C10G8.7 C10G8.7 P W All gene names: ceh-33; C10G8.7; 5F800; CE08078; HM33_CAEEL; NM_072019; WBGene00000454; WP:CE08078 WormBase description: ceh-33 encodes a Six/sine oculis class homeodomain transcription factor; preliminary RNAi experiments suggest that CEH-33 activity may be required for gonad development; a ceh-33::gfp reporter shows very weak pharyngeal expression in late embryos and early larvae.
C11E4.1 C11E4.1 P W All gene names: C11E4.1; CE31410; WBGene00007516; WP:CE31410; XK203 WormBase description: glutathione peroxidase
C11E4.6 C11E4.6 P W All gene names: C11E4.6; CE31411; Q93203_CAEEL; WBGene00007520; WP:CE31411; XK235 WormBase description: ankyrin repeats
C11G6.4 C11G6.4 P W All gene names: nhr-28; C11G6.4; C11G6.4a.1; C11G6.4a.2; C11G6.4b.1; C11G6.4b.2; C11G6.4b.3; CE27061; CE37954; NHR28_CAEEL; WBGene00003624; WP:CE27061; WP:CE37954; XQ973 WormBase description: nuclear hormone receptor, nhr-28
C12C8.1 C12C8.1 P W All gene names: hsp-70; C12C8.1; 1J898; CE08110; NM_060084; WBGene00002026; WP:CE08110 WormBase description: hsp-70 encodes a member of the hsp70 family. WormBase CDS description: heat shock protein 70
C13B4.1 C13B4.1 P W All gene names: C13B4.1; 2O756; CE35395; WBGene00007545; WP:CE35395
C13C4.2 C13C4.2 P W All gene names: nhr-154; C13C4.2; 5M581; CE08127; NH154_CAEEL; WBGene00007547; WP:CE08127 WormBase description: Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains)
C13C4.4 C13C4.4 P W All gene names: C13C4.4; 5M590; CE20504; WBGene00007548; WP:CE20504
C13D9.9 C13D9.9 P W All gene names: ugt-7; C13D9.9; 5F472; CE38484; WBGene00015739; WP:CE38484 WormBase description: 7TM chemoreceptor, ugt family
C13F10.4 C13F10.4 P W All gene names: C13F10.4; 5H686; CE08145; WBGene00015743; WP:CE08145
C14A11.7 C14A11.7 P W All gene names: ssr-2; C14A11.7; CE39675; NM_076089; WBGene00006055; WP:CE39675; XD440 WormBase description: RAS-related protein
C14A4.1 C14A4.1 P W All gene names: tag-242; C14A4.1; C14A4.1.1; C14A4.1.2; CE02138; DOHH_CAEEL; WBGene00007555; WP:CE02138
C14A4.2 C14A4.2 P W All gene names: dap-3; C14A4.2; 2K873; CE24802; NM_063879; WBGene00000933; WP:CE24802 WormBase description: dap-3 is an ortholog of mammalian death-associated protein 3 (DAP3), a mitochondrial ribosomal protein that promotes apoptosis.
C14A6.1 C14A6.1 P W All gene names: clec-48; C14A6.1; 5S639; CE18493; WBGene00007565; WP:CE18493 WormBase description: Lectin C-type domain short and long forms (2 domains)
C14B1.1 C14B1.1 P W All gene names: pdi-1; C14B1.1; C14B1.1.1; C14B1.1.2; 3E790; CE00897; NM_065345; PDI1_CAEEL; WBGene00003962; WP:CE00897 WormBase description: protein disulfide isomerase
C14C10.1 C14C10.1 P W All gene names: C14C10.1; 5N69; CE05280; WBGene00007584; WP:CE05280 WormBase description: mitochondrial carrier protein
C14C11.3 C14C11.3 P W All gene names: C14C11.3; C14C11.3.1; C14C11.3.2; 5G137; CE36785; WBGene00015767; WP:CE36785
C14E2.2 C14E2.2 P W All gene names: C14E2.2; CE06829; WBGene00015771; WP:CE06829; XC422 WormBase description: aspartate aminotransferase
C14E2.4 C14E2.4 P W All gene names: C14E2.4; CE06831; WBGene00015773; WP:CE06831; XC430
C14F11.5 C14F11.5 P W All gene names: hsp-43; C14F11.5; CE03986; HSP43; NM_076644; Q17992_CAEEL; WBGene00002024; WP:CE03986; XG852 WormBase description: hsp-43 encodes a member of the hsp20 family. WormBase CDS description: heat shock protein
C14F5.5 C14F5.5 P W All gene names: sem-5; C14F5.5; CE01784; NM_076941; SEM5_CAEEL; WBGene00004774; WP:CE01784; XI578 WormBase description: sem-5 encodes a Src homology (SH) domain 2 and 3-containing protein, orthologous to human GRB2 (OMIM:108355), that functions in multiple signaling pathways during development; these pathways include those regulating sex myoblast migration, muscle membrane extension, vulval induction, fluid balance, viability, and formation of the male tail; SEM-5 acts downstream of the LET-23 epidermal growth factor receptor to negatively regulate RAS-, MAP-, as well as IP-3-, mediated signal transduction. WormBase CDS description: C. elegans sem-5
C14H10.3 C14H10.3 P W All gene names: C14H10.3; CE03020; WBGene00007593; WP:CE03020; XK840 WormBase description: terminase domain
C15A7.2 C15A7.2 P W All gene names: C15A7.2; CE35399; WBGene00007595; WP:CE35399; XM690
C15B12.1 C15B12.1 P W All gene names: C15B12.1; CE29665; SOX_CAEEL; WBGene00015783; WP:CE29665; XH97 WormBase description: sarcosine oxidase
C15C7.7 C15C7.7 P W All gene names: C15C7.7; CE36786; OFUT1_CAEEL; WBGene00015793; WP:CE36786; XD785
C15C8.2 C15C8.2 P W All gene names: cky-1; C15C8.2; 5N221; CE30427; NM_073783; Q18018_CAEEL; WBGene00000521; WP:CE30427 WormBase description: cky-1 encodes a member of the basic-helix-loop-helix-PAS (bHLH-PAS) protein family; it is likely that CKY-1 together with AHA-1, another bHLH-PAS protein, has a role in pharyngeal function; CKY-1 is expressed in most non-neuronal pharyngeal cells. WormBase CDS description: Human ARNT-interacting protein like
C15C8.4 C15C8.4 P W All gene names: C15C8.4; C15C8.4.1; C15C8.4.2; 5N226; CE39472; WBGene00007606; WP:CE39472 WormBase description: Human alpha-2-macroglobulin receptor-associated protein like
C15F1.4 C15F1.4 P W All gene names: ppp-1; C15F1.4; C15F1.E; 2H256; CE23548; EI2BG_CAEEL; NM_063027; WBGene00004090; WP:CE23548 WormBase description: translation initiation factor
C15F1.7 C15F1.7 P W All gene names: sod-1; C15F1.7; C15F1.7b.1; C15F1.7b.2; C15F1.B; 2H264; CE20508; CE23550; NM_063030; SODC_CAEEL; WBGene00004930; WP:CE20508; WP:CE23550 WormBase description: The sod-1 gene encodes an ortholog of human SOD1 (OMIM:147450), which when mutated leads to amyotrophic lateral sclerosis (OMIM:105400).
C15H11.6 C15H11.6 P W All gene names: nxf-2; C15H11.6; 5O896; CE36102; NM_074167; NXF2_CAEEL; WBGene00003835; WP:CE36102 WormBase description: nxf-2 encodes a predicted homolog of human TAP protein, a member of the NXF family of shuttling transport receptors for nuclear export of mRNA, and it affects embryonic viability.
C15H9.1 C15H9.1 P W All gene names: nnt-1; C15H9.1; CE08176; NM_076627; WBGene00003778; WP:CE08176; XG745 WormBase description: nnt-1 encodes a proton-pumping nicotinamide nucleotide transhydrogenase predicted to be mitochondrial. WormBase CDS description: NAD(P) transhydrogenase, mitochondrial
C16A3.3 C16A3.3 P W All gene names: C16A3.3; 3H477; CE27690; NM_065997; WBGene00015808; WP:CE27690
C16A3.7 C16A3.7 P W All gene names: tag-182; C16A3.7; 3H467; CE04007; WBGene00007048; WBGene00015812; WP:CE04007 WormBase description: human NFX1; D. melanogaster shuttle craft protein
C16A3.9 C16A3.9 P W All gene names: rps-13; C16A3.9; C16A3.9.1; C16A3.9.2; 3H464; CE04009; NM_065992; RS13_CAEEL; WBGene00004482; WP:CE04009 WormBase description: rps-13 encodes a small ribosomal subunit S13 protein; by homology, RPS-13 is predicted to function in protein biosynthesis; in C. elegans, RPS-13 activity is required for embryonic and germline development. WormBase CDS description: 40S ribosomal protein S13
C16B8.1 C16B8.1 P W All gene names: lin-18; C16B8.1; C16B8.1.1; C16B8.1.2; CE27692; NM_076283; WBGene00003007; WP:CE27692; XE579 WormBase description: lin-18 encodes a predicted receptor tyrosine kinase that is a member of the Ryk/Derailed family of tyrosine kinase-related receptors (OMIM:600524, mutations in humans are associated with cleft palate); in C. elegans, LIN-18 is required for establishing the polarity of the secondary vulval cell lineage produced by the P7.p vulval precursor cell; LIN-18 may be a receptor for Wnt-like signaling molecules, and in vulval development appears to function independently of, but in parallel with, LIN-17, a Frizzled-like Wnt receptor, also required for proper orientation of the P7.p lineage; a lin-18 reporter gene is expressed in body wall muscle, neurons, and the developing vulva; in the vulva, expression is detected in P5.p, P6.p, and P7.p and all of their descendants during the L3 and L4 larval stages. WormBase CDS description: protein tyrosine kinase
C16C2.1 C16C2.1 P W All gene names: ceh-5; C16C2.1; 1K303; CE15618; HM05_CAEEL; NM_060185; WBGene00000430; WP:CE15618 WormBase description: ceh-5 encodes a homeodomain protein, similar to the human VENTRAL ANTERIOR HOMEO BOX 2 gene (VAX2; OMIM:604295); CEH-5 is dispensable for viability and gross morphology. WormBase CDS description: Homeobox domain
C16D9.6 C16D9.6 P W All gene names: C16D9.6; 5I726; CE35240; WBGene00015861; WP:CE35240
C17G1.7 C17G1.7 P W All gene names: C17G1.7; C17G1.7.1; C17G1.7.2; CE39223; WBGene00007653; WP:CE39223; XK572 WormBase description: cysteine synthase
C17H12.2 C17H12.2 P W All gene names: C17H12.2; 4H552; CE16863; WBGene00015928; WP:CE16863
C17H12.3 C17H12.3 P W All gene names: C17H12.3; 4H558; CE16864; WBGene00015929; WP:CE16864 WormBase description: protein-tyrosine phosphatase
C18A3.3 C18A3.3 P W All gene names: C18A3.3; 2G7; CE28890; EBP2_CAEEL; WBGene00015941; WP:CE28890
C18C4.3 C18C4.3 P W All gene names: ugt-48; C18C4.3; 5G26; CE38487; UGT48_CAEEL; WBGene00015965; WP:CE38487 WormBase description: 7TM chemoreceptor, ugt family
C18E3.5 C18E3.5 P W All gene names: C18E3.5; 1E771; CE27713; WBGene00015974; WP:CE27713 WormBase description: beta transducin
C18E9.10 C18E9.10 P W All gene names: C18E9.10; 2J246; CE20520; WBGene00007690; WP:CE20520
C18E9.2 C18E9.2 P W All gene names: C18E9.2; 2J255; CE34703; WBGene00007683; WP:CE34703 WormBase description: Drosophila translocation protein 1 like
C18H9.3 C18H9.3 P W All gene names: C18H9.3; 2G981; CE01803; WBGene00016002; WP:CE01803
C18H9.5 C18H9.5 P W All gene names: C18H9.5; 2G984; CE01805; WBGene00016003; WP:CE01805 WormBase description: sodium/phosphate transport protein
C23H3.3 C23H3.3 P W All gene names: C23H3.3; 2A349; CE08322; P91080_CAEEL; WBGene00016019; WP:CE08322
C23H3.4 C23H3.4 P W All gene names: sptl-1; C23H3.4; C23H3.4a.1; C23H3.4a.2; C23H3.4a.3; C23H3.4b.1; C23H3.4b.2; 2A347; CE08323; CE37749; WBGene00016020; WP:CE08323; WP:CE37749 WormBase description: C23H3.4 encodes a putative serine palmitoyltransferase required for normal embryonic and larval developement, locomotion, and speed of growth.
C23H4.7 C23H4.7 P W All gene names: C23H4.7; CE39325; WBGene00007695; WP:CE39325; XM843 WormBase description: carboxyesterase
C23H5.7 C23H5.7 P W All gene names: C23H5.7; 4C868; CE17439; WBGene00016026; WP:CE17439 WormBase description: cyclic nucleotide-binding protein
C24A3.1 C24A3.1 P W All gene names: C24A3.1; CE04058; WBGene00016032; WP:CE04058; XJ625 WormBase description: Neuropeptide anthorfamide
C24A3.7 C24A3.7 P W All gene names: C24A3.7; WBGene00016035; XJ618
C24A8.3 C24A8.3 P W All gene names: pqn-15; C24A8.3; CE27080; NM_076337; WBGene00004106; WP:CE27080; XE922 WormBase description: The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
C24G6.4 C24G6.4 P W All gene names: Csr-1; nhr-279; nhr-47; C24G6.4; C24G6.4.1; C24G6.4.2; 5F989; CE27727; NHR47_CAEEL; NM_072054; WBGene00003637; WP:CE27727 WormBase description: nhr-47 is predicted to encode a nuclear hormone receptor (NHR); gene expression of nhr-47 appears to be induced upon exposure of worm cultures to estradiol. WormBase CDS description: zinc finger protein
C24G6.8 C24G6.8 P W All gene names: C24G6.8; C24G6.8.1; C24G6.8.2; C24G6.8.3; 5G16; CE17464; PTH2_CAEEL; WBGene00016062; WP:CE17464
C24H11.2 C24H11.2 P W All gene names: C24H11.2; 3M880; CE18525; WBGene00007700; WP:CE18525 WormBase description: Protein phosphatase-1 (PP1)
C24H11.8 C24H11.8 P W All gene names: twk-39; C24H11.8; 3M891; CE31773; NM_067128; WBGene00006690; WP:CE31773
C25A1.12 C25A1.12 P W All gene names: C25A1.12; 1K768; CE08378; WBGene00007711; WP:CE08378
C25D7.3 C25D7.3 P W All gene names: dpy-29; sdc-3; C25D7.3; 5P520; CE08389; NM_074302; SDC3_CAEEL; WBGene00004747; WP:CE08389 WormBase description: sdc-3 encodes a protein that contains two mutationally separable domains: a zinc finger motif required for dosage compensation and a myosin- like putative ATP- binding region required for her-1 regulation of sex determination; SDC-3 activates dosage compensation by directing the dosage compensation protein complex to the hermaphrodite X chromosomes, and is functionally redundant with SDC-2 with respect to dosage compensation; SDC-1, SDC-2, and SDC-3 proteins form a complex. WormBase CDS description: Zinc finger, C2H2 type
C25E10.4 C25E10.4 P W All gene names: C25E10.4; 5J515; CE36982; WBGene00016094; WP:CE36982
C25G4.10 C25G4.10 P W All gene names: C25G4.10; 4N233; CE28206; WBGene00007736; WP:CE28206; YPG43_CAEEL WormBase description: fibronectin
C25G4.2 C25G4.2 P W All gene names: C25G4.2; 4N208; CE05303; WBGene00007730; WP:CE05303 WormBase description: dihydrofolate reductase like
C26B2.4 C26B2.4 P W All gene names: nhr-258; C26B2.4; 4I809; CE34709; WBGene00016126; WP:CE34709 WormBase description: nuclear hormone receptor
C26B9.5 C26B9.5 P W All gene names: C26B9.5; CE04098; WBGene00016134; WP:CE04098; XF949 WormBase description: lysosomal Pro-X carboxypeptidase
C26C6.3 C26C6.3 P W All gene names: nas-36; C26C6.3; 1I107; CE38281; NAS36_CAEEL; NM_059708; WBGene00003552; WP:CE38281 WormBase description: zinc metalloprotease
C26D10.3 C26D10.3 P W All gene names: C26D10.3; 2I617; CE36983; WBGene00007744; WP:CE36983 WormBase description: oxidoreductase
C26E6.6 C26E6.6 P W All gene names: C26E6.6; C26E6.6.1; C26E6.6.2; 3G25; CE39477; RM03_CAEEL; WBGene00016142; WP:CE39477 WormBase description: Ribosomal protein L3
C26F1.2 C26F1.2 P W All gene names: cyp-32A1; C26F1.2; 5I263; CE39228; NM_072608; WBGene00016147; WP:CE39228 WormBase description: cytochrome P450
C26G2.2 C26G2.2 P W All gene names: C26G2.2; CE37322; Q9U3P1_CAEEL; WBGene00007751; WP:CE37322; XP289
C27A2.6 C27A2.6 P W All gene names: dsh-2; C27A2.6; 2F370; CE27097; NM_062536; Q18239_CAEEL; WBGene00001102; WP:CE27097 WormBase description: dsh-2 encodes a protein containing a DIX domain, a DEP domain, and a PDZ domain that is required for embryonic viability and functions in Wnt pathway signaling between the embryonic blastomeres P2 and EMS with respect to endoderm specification and to orient the division axis of the EMS cell; expressed from the four-cell embryo stage, and is primarily associated with membranes.
C27A7.3 C27A7.3 P W All gene names: C27A7.3; 5M623; CE39479; ENPP2_CAEEL; WBGene00007755; WP:CE39479 WormBase description: Human plasma-cell membrane glycoprotein PC-1 like
C27A7.4 C27A7.4 P W All gene names: che-11; mev-4; C27A7.4; 5M626; CE39480; NM_073646; WBGene00000490; WP:CE39480 WormBase description: che-11 encodes a large, unfamiliar protein with orthologs in vertebrates and arthropods (e.g., KIAA0590 and CG11838-PA) and in Chlamydomonas (IFT140), as well as distant similarity to OSM-1 and ZK520.1; che-11 is required for normal synthesis of sensory cilia (via intraflagellar transport) in sensory neurons, osmotic avoidance, and dauer formation.
C27A7.6 C27A7.6 P W All gene names: C27A7.6; 5M604; CE08409; WBGene00007757; WP:CE08409
C27C12.4 C27C12.4 P W All gene names: C27C12.4; CE33976; WBGene00007774; WP:CE33976; XP473
C27F2.1 C27F2.1 P W All gene names: C27F2.1; 3G79; CE38940; WBGene00016165; WP:CE38940
C27F2.10 C27F2.10 P W All gene names: C27F2.10; 3G76; CE29189; PCID_CAEEL; WBGene00016171; WP:CE29189
C28D4.2 C28D4.2 P W All gene names: cka-1; C28D4.2; 4K498; CE20533; NM_069331; WBGene00000509; WP:CE20533 WormBase description: cka-1 encodes an isoform of choline kinase whose activity has been verified in vitro, and that has a strong preference for choline over ethanolamine; CKA-1 and CKA-2 comprise a related group ('A') of choline kinases. WormBase CDS description: choline kinase
C28G1.1 C28G1.1 P W All gene names: ubc-23; C28G1.1; CE37613; NM_077097; WBGene00006718; WP:CE37613; XJ467 WormBase description: ubc-23 encodes a predicted conjugating enzyme (UBCs/E2s) of the ubiquitin-conjugation system; expressed in larvae and adults in cells around the pharynx and in intestinal cells. WormBase CDS description: ubiquitin-conjugating enzyme
C29E4.12 C29E4.12 P W All gene names: C29E4.12; 3J31; CE30619; WBGene00016209; WP:CE30619
C29E4.8 C29E4.8 P W All gene names: C29E4.8; C29E4.8.1; C29E4.8.2; 3J40; CE29198; KADX_CAEEL; WBGene00016205; WP:CE29198 WormBase description: Adenylate kinase
C29E6.1 C29E6.1 P W All gene names: let-653; C29E6.1; C29E6.1b.1; C29E6.1b.2; 4M655; CE05332; CE37323; WBGene00002827; WP:CE05332; WP:CE37323 WormBase description: let-653 encodes a mucin-like protein similar to the highly glycosylated mucins secreted by the apical surface of epithelia and believed to provide a protective barrier to exposed cellular surfaces; LET-653 is required for viability, locomotion, and for maintaining the tubular epithelial structure of the excretory cell canals. WormBase CDS description: LET-653 mucin like protein
C29E6.2 C29E6.2 P W All gene names: trpa-1; C29E6.2; 4M639; CE37324; TRPA1_CAEEL; WBGene00007801; WP:CE37324 WormBase description: ankyrin repeats
C29F3.1 C29F3.1 P W All gene names: ech-1; C29F3.1; 5P838; CE08435; NM_074409; WBGene00001150; WP:CE08435 WormBase description: long-chain enoyl-CoA hydratase
C29F4.1 C29F4.1 P W All gene names: col-125; C29F4.1; C29F4.1.1; C29F4.1.2; 4L991; CE03038; NM_069706; WBGene00000699; WP:CE03038 WormBase description: collagen
C29F7.4 C29F7.4 P W All gene names: fkh-3; C29F7.4; CE08445; NM_077836; WBGene00001435; WP:CE08445; XO40 WormBase description: fkh-3 encodes one of 15 C. elegans forkhead transcription factors; loss of fkh-3 activity via RNAi, either singly or in combination with the closely related fkh-4 and fkh-5 genes, results in no obvious abnormalities, suggesting functional redundancy with other genes; an FKH-3 reporter fusion is expressed in most, but not all, cells of the early embryo from the 20- to the 200-cell stage. WormBase CDS description: fork head domain protein
C29F7.6 C29F7.6 P W All gene names: C29F7.6; CE08447; WBGene00007813; WP:CE08447; XO59
C29H12.1 C29H12.1 P W All gene names: rrt-2; C29H12.1; 2G417; CE17479; NM_062826; WBGene00004680; WP:CE17479 WormBase description: arginyl-tRNA synthetase
C30A5.4 C30A5.4 P W All gene names: C30A5.4; 3J313; CE00095; WBGene00016239; WP:CE00095; YK84_CAEEL
C30D11.1 C30D11.1 P W All gene names: unc-103; C30D11.1; 3F235; CE27805; NM_065423; WBGene00006830; WP:CE27805 WormBase description: unc-103 encodes an ERG-like K+ channel homolog, orthologous to human KCNH6 (OMIM:608168); UNC-103 regulates muscle activation in motility, egg-laying and male spicule protraction; UNC-103 is expressed highly in many neurons; gain-of-function alleles can be uncoordinated, while loss-of-function alleles have a more subtle defect in copulatory spicule protraction. WormBase CDS description: potassium channel protein
C30F12.7 C30F12.7 P W All gene names: C30F12.7; 1H553; CE16887; WBGene00016266; WP:CE16887 WormBase description: isocitrate dehydrogenase
C30F8.2 C30F8.2 P W All gene names: vha-16; C30F8.2; C30F8.2.1; C30F8.2.2; C30F8.2.3; C30F8.2.4; 1F648; CE29684; NM_059114; WBGene00016258; WP:CE29684 WormBase description: vha-16 encodes an an ortholog of subunit d of the membrane-bound (V0) domain of vacuolar proton-translocating ATPase (V-ATPase); VHA-16 is predicted to mechanically anchor the V-ATPase cytosolic rotor (stalk) to the membrane, while also providing a hub for the V-ATPase transmembrane rotor; vha-16 is expressed in diverse tissues (e.g., excretory cell, pharynx, intestine, hypodermis, and neurons). WormBase CDS description: vaculolar ATPase
C30G12.7 C30G12.7 P W All gene names: puf-8; C30G12.7; 2H586; CE37486; NM_063122; WBGene00004244; WP:CE37486
C30G4.7 C30G4.7 P W All gene names: C30G4.7; CE27806; WBGene00016272; WP:CE27806
C30H6.11 C30H6.11 P W All gene names: C30H6.11; 4S301; CE34720; WBGene00007828; WP:CE34720
C30H6.7 C30H6.7 P W All gene names: C30H6.7; 4S325; CE15651; WBGene00007824; WP:CE15651 WormBase description: 2-oxo acid dehydrogenases acyltransferase (catalytic domain)
C30H7.2 C30H7.2 P W All gene names: C30H7.2; C30H7.2a.1; C30H7.2a.2; C30H7.2a.3; C30H7.2a.4; 1F986; CE27807; CE39231; WBGene00016278; WP:CE27807; WP:CE39231
C31H5.3 C31H5.3 P W All gene names: acr-19; C31H5.3; 1J608; CE30494; NM_060028; WBGene00000058; WP:CE30494 WormBase description: acr-19 encodes a predicted member of the alpha subunit family of nicotinic acetylcholine receptors. WormBase CDS description: nicotinic acetylcholine receptor
C32D5.2 C32D5.2 P W All gene names: sma-6; C32D5.2; 2G617; CE01842; NM_062870; SMA6_CAEEL; WBGene00004860; WP:CE01842 WormBase description: sma-6 encodes a serine/threonine protein kinase that is orthologous to type I TGF-beta receptors; sma-6 activity is required for regulating body length and for proper development of the male tail; sma-6 expression first begins at the 1.5-fold stage of embryogenesis and continues through adulthood; sma-6 is expressed in dorsal and ventral hypodermis, pharyngeal muscle, and the intestine; expression in the hypodermis is necessary and sufficient for body length regulation. WormBase CDS description: Activin receptor
C32D5.5 C32D5.5 P W All gene names: tag-337; C32D5.5; C32D5.5.1; C32D5.5.2; 2G620; CE01845; TG337_CAEEL; WBGene00016313; WP:CE01845
C32E12.2 C32E12.2 P W All gene names: pde-5; C32E12.2; 1F767; CE04134; NM_059143; PDE5_CAEEL; WBGene00016328; WP:CE04134 WormBase description: cyclic nucleotide phosphodiesterase
C32E12.5 C32E12.5 P W All gene names: sox-1; C32E12.5; C32E12.5.1; C32E12.5.2; 1F774; CE30497; NM_170859; WBGene00004948; WP:CE30497
C32E8.3 C32E8.3 P W All gene names: C32E8.3; 1E355; CE08527; WBGene00016321; WP:CE08527; YBYK_CAEEL
C33A11.4 C33A11.4 P W All gene names: tag-97; C33A11.4; CE31678; WBGene00006462; WBGene00007879; WP:CE31678; XP990 WormBase description: Ets-domain
C33A12.1 C33A12.1 P W All gene names: C33A12.1; 4K286; CE05347; NDUA5_CAEEL; WBGene00007880; WP:CE05347 WormBase description: C33A12.1 encodes the C. elegans ortholog of the NDUFA5/B13 subunit of the mitochondrial NADH dehydrogenase (ubiquinone) complex (complex I). WormBase CDS description: NADH-ubiquinone oxidoreductase 13 KD-B subunit
C33D3.1 C33D3.1 P W All gene names: elt-2; C33D3.1; CE31430; ELT2_CAEEL; GATA; NM_077354; WBGene00001250; WP:CE31430; XL101 WormBase description: elt-2 encodes a GATA-type transcription factor most similar to the vertebrate GATA4-6 transcription factors required for cardiac and endoderm development (OMIM:601656, 600576); in C. elegans, ELT-2 is required redundantly with ELT-7 for initiating and maintaining terminal differentiation of the intestine; ELT-2 is expressed solely in the intestine, beginning embryonically at the 2E-cell stage and continuing in all intestinal cells throughout the life of the animal; in the regulatory hierarchy controlling endoderm development, ELT-2 lies downstream of the maternal regulators SKN-1 and POP-1 and the embryonic GATA factors MED-1/-2, and END-1/-3; in turn, ELT-2, along with ELT-7, likely regulates transcription of a number of intestine-specific terminal differentiation genes such as ges-1, ifb-2, pha-4, and the stress-induced mtl-2; ELT-2 also positively autoregulates, presumably to ensure maintenance of intestinal differentiation WormBase CDS description: zinc finger protein (GATA type)
C33E10.10 C33E10.10 P W All gene names: C33E10.10; CE17495; O61799_CAEEL; WBGene00016350; WP:CE17495; XR912
C33G3.4 C33G3.4 P W All gene names: C33G3.4; CE08560; MANBA_CAEEL; WBGene00007904; WP:CE08560; XO693 WormBase description: C33G3.4 is orthologous to the human gene BETA-MANNOSIDASE (MANBA; OMIM:248510), which when mutated leads to disease. WormBase CDS description: beta-mannosidase
C33H5.17 C33H5.17 P W All gene names: C33H5.17; 4I576; CE04160; WBGene00016383; WP:CE04160
C33H5.6 C33H5.6 P W All gene names: C33H5.6; 4I541; CE04149; WBGene00016373; WP:CE04149
C34D4.1 C34D4.1 P W All gene names: C34D4.1; 4H923; CE27742; WBGene00016397; WP:CE27742
C34E10.8 C34E10.8 P W All gene names: C34E10.8; 3G340; CE32158; WBGene00016409; WP:CE32158; YLB8_CAEEL
C34E11.1 C34E11.1 P W All gene names: rsd-3; C34E11.1; C34E11.1.1; C34E11.1.2; CE03062; NM_077572; WBGene00004682; WP:CE03062; XM421 WormBase description: yeast hypothetical L8167.6 like
C34F6.2 C34F6.2 P W All gene names: col-178; C34F6.2; CE15671; NM_077468; WBGene00000751; WP:CE15671; XL819 WormBase description: collagen
C34G6.4 C34G6.4 P W All gene names: pgp-2; C34G6.4; 1G471; CE29212; NM_059306; WBGene00003996; WP:CE29212 WormBase description: pgp-2 encodes a member of the ABC transporter family with highest similarity to the vertebrate MDR (multidrug resistance) family, and is orthologous to human MDR1 (ABCB1; OMIM:171050, mutated in Crohn disease); PGP-2 is expressed at lower levels during the embryonic stages with higher expression later in development. WormBase CDS description: abc transporter
C34G6.5 C34G6.5 P W All gene names: C34G6.5; 1G449; CE26909; WBGene00016421; WP:CE26909 WormBase description: ser/thr-protein kinase
C35A5.3 C35A5.3 P W All gene names: C35A5.3; 5K980; CE37880; WBGene00007947; WP:CE37880 WormBase description: sodium/phosphate transport protein
C35A5.8 C35A5.8 P W All gene names: C35A5.8; 5L4; CE15680; WBGene00007952; WP:CE15680
C35C5.6 C35C5.6 P W All gene names: C35C5.6; CE03069; WBGene00007956; WP:CE03069; XM187
C35D10.14 C35D10.14 P W All gene names: clec-5; C35D10.14; 3F972; CE27828; WBGene00016450; WP:CE27828 WormBase description: 7TM chemoreceptor, clec family
C35D6.4 C35D6.4 P W All gene names: C35D6.4; 4R103; CE15683; WBGene00007961; WP:CE15683 WormBase description: Zinc finger C-x8-C-x5-C-x3-H type (and similar). (2 domains)
C36B1.10 C36B1.10 P W All gene names: C36B1.10; 1J326; CE05377; WBGene00007977; WP:CE05377 WormBase description: serine/threonine kinase
C36B1.3 C36B1.3 P W All gene names: C36B1.3; 1J307; CE39091; WBGene00007971; WP:CE39091 WormBase description: DNA directed RNA polymerase II
C36B1.5 C36B1.5 P W All gene names: C36B1.5; C36B1.5.1; C36B1.5.2; 1J310; CE05372; Q93339_CAEEL; WBGene00007972; WP:CE05372 WormBase description: U4/U6 small nuclear ribonucleoprotein
C36E6.5 C36E6.5 P W All gene names: mlc-2; C36E6.5; C36E6.5.1; C36E6.5.2; C36E6.B; CE20542; MLR2_CAEEL; NM_078427; WBGene00003370; WP:CE20542; XS70 WormBase description: mlc-2 encodes, along with mlc-1 and mlc-4, one of three C. elegans regulatory myosin light chains; MLC-2 is predicted to function as a regulator of myosin ATPase activity, and genetic studies indicate that MLC-2 is nearly essential in hermaphrodites for normal pharyngeal muscle function, but redundant with MLC-1, with which it is nearly identical, for proper bodywall muscle development; accordingly, loss of mlc-2 activity eventually results in larval lethality, as animals are not able to feed properly; mlc-2 mRNA is expressed in bodywall, pharyngeal, and vulval muscles.
C36E8.1 C36E8.1 P W All gene names: C36E8.1; C36E8.1.1; C36E8.1.2; 3F90; CE00909; WBGene00007980; WP:CE00909; YPJ1_CAEEL
C36F7.1 C36F7.1 P W All gene names: irx-1; C36F7.1; 1K114; CE17526; IRX1_CAEEL; WBGene00007984; WP:CE17526 WormBase description: irx-1 encodes a homeodomain-containing protein that is most similar to members of the Iroquois subclass of TALE (three amino acid loop extension) superclass atypical homeodomain proteins; IRX-1 is predicted to function as a transcriptional regulator during development, but as loss of irx-1 activity via RNAi results in no obvious defects, the precise role of irx-1 in C. elegans development and/or behavior is not yet known. WormBase CDS description: Homeobox domain
C36H8.1 C36H8.1 P W All gene names: C36H8.1; 4N508; CE05380; Q18503_CAEEL; WBGene00007987; WP:CE05380 WormBase description: major sperm protein like
C37C3.3 C37C3.3 P W All gene names: phi-63; C37C3.3; 5I331; CE39687; WBGene00016497; WP:CE39687
C37H5.1 C37H5.1 P W All gene names: nex-4; C37H5.1; 5F337; CE08625; NM_071899; WBGene00003591; WP:CE08625 WormBase description: nex-4 encodes a predicted annexin. WormBase CDS description: annexin
C38D4.6 C38D4.6 P W All gene names: ceh-3; nob-2; pal-1; C38D4.6; C38D4.6a.1; C38D4.6a.2; C38D4.6b.1; C38D4.6b.2; 3F896; CE05383; CE27837; NM_065590; PAL1_CAEEL; WBGene00003912; WP:CE05383; WP:CE27837 WormBase description: pal-1 encodes a homeodomain protein that is the C. elegans Caudal ortholog; PAL-1 is required maternally and embryonically for cell fate specification and posterior patterning during embryogenesis; PAL-1 is also required postembryonically for fate specification of the posterior V6 neuroectoblast during male tail development; PAL-1 is expressed in posterior blastomeres beginning at the four-cell stage of embryogenesis and its expression continues during embryogenesis in posterior-derived tissues and cells undergoing movement or forming midline structures; pal-1 is subject to both transcriptional and translational regulation.
C38D4.8 C38D4.8 P W All gene names: arl-query; bbs-3; C38D4.8; 3F900; ARL6_CAEEL; CE00921; NM_065592; WBGene00000193; WP:CE00921 WormBase description: arl-6 encodes an ADP-Ribosylation factor-Like member of the Ras superfamily of small GTP-binding proteins and is a predicted homolog of the human ARL6 gene, identified as the gene that underlies Bardet-Biedl syndrome type 3; GFP-tagged ARL-6 undergoes intraflagellar transport (IFT) in the ciliary axoneme, implicating ARL-6 in ciliary transport; arl-6 is expressed in amphid and phasmid ciliated sensory neurons. WormBase CDS description: ADP-ribosylation factor
C39E6.4 C39E6.4 P W All gene names: mls-2; C39E6.4; CE30891; NM_076414; WBGene00003377; WP:CE30891; XF378
C39E9.6 C39E9.6 P W All gene names: C39E9.6; 4N837; CE05389; WBGene00008030; WP:CE05389 WormBase description: testis-specific protein TPX-1 like
C40C9.2 C40C9.2 P W All gene names: acr-9; C40C9.2; CE37330; NM_077884; WBGene00000048; WP:CE37330; XO262 WormBase description: acr-9 encodes a predicted member of the alpha subunit family of nicotinic acetylcholine receptors. WormBase CDS description: acetylcholine receptor
C40H1.3 C40H1.3 P W All gene names: C40H1.3; 3K416; CE00111; WBGene00008039; WP:CE00111; YLF3_CAEEL
C40H5.4 C40H5.4 P W All gene names: C40H5.4; CE08652; WBGene00008047; WP:CE08652; XM375 WormBase description: B.subtilis penicillin-binding protein like
C40H5.5 C40H5.5 P W All gene names: ttx-3; C40H5.5; CE27107; NM_077569; WBGene00006654; WP:CE27107; XM384 WormBase description: ttx-3 encodes a LIM homeodomain protein required for functions of the interneuron AIY, including thermosensory behavior and olfactory learning. WormBase CDS description: LIM domain containing proteins (2 domains), homeobox protein (lim subfamily)
C41C4.6 C41C4.6 P W All gene names: ulp-4; C41C4.6; 2I423; CE01521; NM_063302; ULP4_CAEEL; WBGene00006739; WP:CE01521
C41D11.2 C41D11.2 P W All gene names: eif-3.H; C41D11.2; 1F13; CE29220; NM_058969; WBGene00001231; WP:CE29220
C41G7.2 C41G7.2 P W All gene names: klp-16; C41G7.2; C41G7.2.1; C41G7.2.2; 1K89; CE08666; NM_060126; WBGene00002226; WP:CE08666 WormBase description: klp-16 encodes a C-terminal motor kinesin orthologous to the Drosophila melanogaster Ncd and Saccharomyces cerevisiae Kar3; however KLP-16 along with KLP-3, KLP-15 and KLP-17 form an unique subgroup based on amino acid sequence and secondary structure analysis; klp-16 is involved in development of the nervous system in embryos and in chromosome segregation; in situ RNA hybridization experiments indicate that klp-16 is localized in the anterior nervous system in the head region of late embryos. WormBase CDS description: kinesin, kinesin-14 family
C41G7.6 C41G7.6 P W All gene names: C41G7.6; 1K102; CE17540; WBGene00008063; WP:CE17540
C41H7.7 C41H7.7 P W All gene names: clec-3; C41H7.7; 2D308; CE32606; WBGene00016577; WP:CE32606 WormBase description: 7TM chemoreceptor, clec family
C42C1.13 C42C1.13 P W All gene names: C42C1.13; 4N43; CE39692; WBGene00016591; WP:CE39692
C42C1.5 C42C1.5 P W All gene names: tag-335; C42C1.5; 4N40; CE16911; WBGene00016583; WP:CE16911 WormBase description: guanyltransferase
C43E11.4 C43E11.4 P W All gene names: EF-Tu2; tufm-2; C43E11.4; 1E817; CE32610; WBGene00007001; WBGene00016604; WP:CE32610 WormBase description: elongation factor Tu
C43E11.7 C43E11.7 P W All gene names: ndx-7; C43E11.7; 1E808; CE30504; NDX7_CAEEL; NM_058935; WBGene00003584; WP:CE30504 WormBase description: ndx-7 encodes a NUDIX hydrolase; by sequence comparison, NDX-7 is predicted to function as a pyrophosphatase, and is most closely related to the mouse RP2 protein that has unknown substrate specificity but is regulated transcriptionally by the presence of androgens; in C. elegans, loss of ndx-7 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, consistent with the proposed nonessential roles for Nudix proteins in eliminating potentially toxic nucleotide metabolites from cells and modulating levels of metabolic intermediates by shuttling them into alternative biochemical pathways.
C43E11.8 C43E11.8 P W All gene names: C43E11.8; 1E812; CE08686; WBGene00016606; WP:CE08686
C43G2.4 C43G2.4 P W All gene names: C43G2.4; CE34750; NM_068599; WBGene00016613; WP:CE34750; YCEL_CAEEL
C44B11.1 C44B11.1 P W All gene names: C44B11.1; 3E247; CE39695; O01908_CAEEL; WBGene00016633; WP:CE39695
C44B7.1 C44B7.1 P W All gene names: C44B7.1; C44B7.1.1; C44B7.1.2; C44B7.1.3; C44B7.1.4; 2H191; CE25810; P27; PSMD9_CAEEL; WBGene00016623; WP:CE25810
C44B9.1 C44B9.1 P W All gene names: C44B9.1; 3L961; CE37754; WBGene00008078; WP:CE37754
C44C1.3 C44C1.3 P W All gene names: ncs-1; C44C1.3; CE24845; NCS1_CAEEL; NM_075785; WBGene00003563; WP:CE24845; XB580 WormBase description: The ncs-1 gene encodes a neuronal calcium sensor protein that, along with calcium, is essential for thermotaxis along isothermal paths in thermal gradients. WormBase CDS description: EF-hand calcium binding proteins
C44E4.7 C44E4.7 P W All gene names: C44E4.7; 1F192; CE23597; WBGene00016656; WP:CE23597
C45B11.3 C45B11.3 P W All gene names: dhs-18; C45B11.3; C45B11.3.1; C45B11.3.2; 5L526; CE05427; NM_073411; WBGene00000981; WP:CE05427 WormBase description: alcohol dehydrogenase
C45G9.2 C45G9.2 P W All gene names: C45G9.2; 3G159; CE29722; WBGene00016674; WP:CE29722; YQI2_CAEEL
C45H4.17 C45H4.17 P W All gene names: cyp-33C2; C45H4.17; Y5H2B.F; 5C663; CE25818; NM_071193; WBGene00016697; WP:CE25818 WormBase description: cytochrome P450
C46A5.1 C46A5.1 P W All gene names: C46A5.1; 4I529; CE08751; WBGene00016698; WP:CE08751 WormBase description: protein-tyrosine phosphatase
C46A5.9 C46A5.9 P W All gene names: hcf-1; C46A5.9; 4I536; CE26914; NM_068878; WBGene00001827; WP:CE26914
C46C2.2 C46C2.2 P W All gene names: C46C2.2; C46C2.2.1; C46C2.2.2; 4J983; CE32832; WBGene00008110; WP:CE32832 WormBase description: transport protein
C46E1.2 C46E1.2 P W All gene names: gcy-36; C46E1.2; CE39007; GCY36_CAEEL; NM_078156; WBGene00001556; WP:CE39007; XQ103 WormBase description: gcy-36 encodes a predicted soluble guanylate cyclase that genetically interacts with npr-1 with respect to feeding behavior; expressed in AQR, PQR, and URX3. WormBase CDS description: GUANYLATE CYCLASE SOLUBLE, BETA-2 CHAIN (EC 4.6.1.2) (76 KD CHAIN)
C46E10.9 C46E10.9 P W All gene names: C46E10.9; 2E18; CE36111; WBGene00016713; WP:CE36111 WormBase description: zinc finger protein
C46H3.3 C46H3.3 P W All gene names: C46H3.3; CE37097; WBGene00016726; WP:CE37097 WormBase description: ankyrin
C47D12.2 C47D12.2 P W All gene names: C47D12.2; C47D12.2.1; C47D12.2.2; 2L967; CE20567; Q18668_CAEEL; WBGene00008136; WP:CE20567 WormBase description: C47D12.2 encodes an ortholog of human FLJ20071/FLJ90130 (dymeclin, OMIM:607461, mutated in Dyggve-Melchior-Clausen dysplasia and Smith-McCort dysplasia), which has no obvious function in mass RNAi assays
C47E8.6 C47E8.6 P W All gene names: C47E8.6; 5P171; CE35839; WBGene00008144; WP:CE35839
C48B4.2 C48B4.2 P W All gene names: rom-2; C48B4.2; 3K680; CE37757; NM_066719; ROM2_CAEEL; WBGene00004401; WP:CE37757 WormBase description: Rhomboid
C48B6.2 C48B6.2 P W All gene names: C48B6.2; C48B6.2.1; C48B6.2.2; 1H493; CE08804; WBGene00016740; WP:CE08804; YS4L_CAEEL WormBase description: ribosomal protein
C48B6.6 C48B6.6 P W All gene names: mab-1; smg-1; C48B6.6; 1H478; CE30258; CE36919; NM_059569; SMG1_CAEEL; WBGene00004879; WP:CE30258; WP:CE36919 WormBase description: kinase
C48B6.8 C48B6.8 P W All gene names: C48B6.8; 1H494; CE32166; WBGene00016744; WP:CE32166
C48E7.5 C48E7.5 P W All gene names: cof-2; col-57; ofm-2; C48E7.5; 1G827; CE36279; NM_059403; WBGene00000583; WP:CE36279 WormBase description: ofm-2 encodes a homolog of human GLC1A, which when mutated leads to glaucome primary open angle (OMIM:137750)
C48E7.9 C48E7.9 P W All gene names: twk-37; C48E7.9; 1G844; CE08824; NM_059409; Q8IG65_CAEEL; WBGene00006689; WP:CE08824
C49A1.2 C49A1.2 P W All gene names: C49A1.2; 1O798; CE15721; WBGene00008185; WP:CE15721 WormBase description: Putative membrane protein
C49A9.8 C49A9.8 P W All gene names: ugt-24; C49A9.8; C49A9.8.1; C49A9.8.2; 4G972; CE33569; WBGene00016762; WP:CE33569 WormBase description: 7TM chemoreceptor, ugt family
C49D10.6 C49D10.6 P W All gene names: nhr-75; C49D10.6; 2E151; CE08847; NHR75_CAEEL; NM_062275; WBGene00003665; WP:CE08847 WormBase description: zinc finger protein
C49F5.4 C49F5.4 P W All gene names: nhr-167; C49F5.4; CE08855; NH167_CAEEL; WBGene00008208; WP:CE08855; XM600 WormBase description: Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains)
C49G7.11 C49G7.11 P W All gene names: C49G7.11; 5E530; CE08869; WBGene00016789; WP:CE08869
C50B6.2 C50B6.2 P W All gene names: C50B6.2; C50B6.2.1; C50B6.2.2; 5N792; CE08871; WBGene00008218; WP:CE08871 WormBase description: histone binding protein
C50B8.2 C50B8.2 P W All gene names: bir-2; C50B8.2; 5O49; CE08882; NM_073961; WBGene00000250; WP:CE08882 WormBase description: The bir-2 gene encodes a protein with two BIR domains that may be involved in apoptosis. WormBase CDS description: Inhibitor of Apoptosis domain.
C50C3.8 C50C3.8 P W All gene names: bath-42; C50C3.8; C50C3.8.1; C50C3.8.2; 3J252; BAT42_CAEEL; CE00124; WBGene00016803; WP:CE00124 WormBase description: The C50C3.8 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis.
C50E3.11 C50E3.11 P W All gene names: C50E3.11; 5I82; CE39703; FOLT2_CAEEL; WBGene00016822; WP:CE39703 WormBase description: folate transporter
C50F4.10 C50F4.10 P W All gene names: C50F4.10; 5K10; CE33984; WBGene00008235; WP:CE33984 WormBase description: serine/threonine kinase
C50F7.10 C50F7.10 P W All gene names: C50F7.10; 4I512; CE04248; WBGene00016848; WP:CE04248 WormBase description: glycosyl hydrolase
C50H11.1 C50H11.1 P W All gene names: C50H11.1; 5D567; CE08917; WBGene00016849; WP:CE08917 WormBase description: ATP-dependent AMP-binding protein
C50H2.1 C50H2.1 P W All gene names: fshr-1; C50H2.1; 5K373; CE28214; WBGene00008239; WP:CE28214; lgr WormBase description: fshr-1 encodes a putative neuropeptide receptor required for normal acetylcholine secretion by synapses; FSHR-1 is orthologous to human follicle-stimulating hormone receptor (OMIM:136435; mutated in ovarian dysgenesis), thyrotropin receptor (OMIM:603372; mutated in hyperthyroidism), and luteinizing hormone receptor (OMIM:152790, mutated in precocious puberty); fshr-1 mutants have abnormally many GFP::SNB-1 puncta at synapses, suggesting exocytotic defects; the requirement for FSHR-1 and ten other predicted neuropeptide signalling proteins in cholinergic neurotransmission indicates that such signalling is important for regulating acetylcholine release at neuromuscular junctions; possible ligands of FSHR-1 are FLP-1 and NLP-12. WormBase CDS description: steroid hormone receptor
C52D10.13 C52D10.13 P W All gene names: col-138; C52D10.13; 4S124; CE17596; NM_070647; WBGene00000711; WP:CE17596 WormBase description: cuticular collagen
C52D10.8 C52D10.8 P W All gene names: skr-13; C52D10.8; 4S106; CE17592; NM_070641; WBGene00004819; WP:CE17592 WormBase description: The skr-13 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-13(RNAi) animals are at least superficially normal. WormBase CDS description: cyclin A-associated protein
C52E4.3 C52E4.3 P W All gene names: snr-4; C52E4.3; C52E4.3.1; C52E4.3.2; 5M460; CE08945; NM_073603; SMD2_CAEEL; WBGene00004917; WP:CE08945 WormBase description: small nuclear ribonucleoprotein D2 like
C52E4.4 C52E4.4 P W All gene names: rpt-1; C52E4.4; C52E4.4.1; C52E4.4.2; C52E4.4.3; 5M462; CE08946; NM_073604; PRS7_CAEEL; WBGene00004501; WP:CE08946 WormBase description: rpt-1 encodes a predicted ATPase subunit of the 19S regulatory complex of the proteasome that affects fertility and embryonic viability. WormBase CDS description: 26S protease regulatory subunit 7
C53B4.5 C53B4.5 P W All gene names: col-119; C53B4.5; 4J744; CE03091; NM_069160; WBGene00000693; WP:CE03091 WormBase description: collagen
C53C11.3 C53C11.3 P W All gene names: ptr-5; C53C11.3; CE34277; NM_078409; WBGene00004220; WP:CE34277; XR939 WormBase description: ptr-5 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-5 is weakly required for normal molting from L4 to adult stages; PTR-5 is also required for normal growth to full size and locomotion; PTR-5 is expressed in head and tail neurons, and in ventral nerve cord.
C53D5.5 C53D5.5 P W All gene names: C53D5.5; C53D5.5.1; C53D5.5.2; C53D5.5.3; CE23612; NM_058313; WBGene00016906; WP:CE23612 WormBase description: The C53D5.5 gene encodes an ortholog of the human gene GAMMA-GLUTAMYLTRANSFERASE 1 (GGT1), which when mutated leads to glutathionuria (OMIM:231950). WormBase CDS description: gamma-glutamyltranspeptidase
C53D6.2 C53D6.2 P W All gene names: unc-129; C53D6.2; 4J768; CE24863; NM_069165; O44371_CAEEL; WBGene00006852; WP:CE24863 WormBase description: The unc-129 gene encodes a member of the TGF-beta family of secreted growth factor signaling molecules; UNC-129 is required for proper axonal guidance of commissural motorneurons and for proper migration of the distal tip cells of the somatic gonad; UNC-129 is expressed in dorsal body wall muscle and at present does not appear to act through the known TGF-beta type I and II receptors. WormBase CDS description: bone morphogenetic protein like
C54A12.2 C54A12.2 P W All gene names: C54A12.2; 2F542; CE36809; WBGene00016909; WP:CE36809
C54C6.1 C54C6.1 P W All gene names: rpl-37; C54C6.1; C54C6.1.1; C54C6.1.2; 3E619; CE05493; NM_065326; RL37_CAEEL; WBGene00004451; WP:CE05493 WormBase description: rpl-37 encodes a large ribosomal subunit L37 protein. WormBase CDS description: 60S ribosomal protein L37
C54C6.6 C54C6.6 P W All gene names: C54C6.6; 3E626; CE33367; WBGene00008288; WP:CE33367 WormBase description: DUF667 domain family
C54D1.2 C54D1.2 P W All gene names: clec-86; C54D1.2; CE06978; WBGene00016912; WP:CE06978; XH759 WormBase description: C-type lectin
C54D1.5 C54D1.5 P W All gene names: C54D1.5; CE30916; LAML1_CAEEL; WBGene00016913; WP:CE30916; XH764
C54F6.4 C54F6.4 P W All gene names: C54F6.4; 5I9; CE08976; WBGene00016922; WP:CE08976
C54G4.7 C54G4.7 P W All gene names: C54G4.7; C54G4.7.1; C54G4.7.2; C54G4.7.3; CE05513; NM_059805; Q18852_CAEEL; WBGene00008317; WP:CE05513
C54G7.4 C54G7.4 P W All gene names: C54G7.4; CE37621; WBGene00016935; WP:CE37621; XG166
C55B6.1 C55B6.1 P W All gene names: C55B6.1; CE35442; CE37215; WBGene00016939; WP:CE35442; WP:CE37215; XH821 WormBase description: glycerol kinase
C55B7.10 C55B7.10 P W All gene names: C55B7.10; 1H78; CE32839; WBGene00016946; WP:CE32839 WormBase description: casein kinase
C55B7.8 C55B7.8 P W All gene names: Ce-dbr1; dbr-1; C55B7.8; 1H68; CE30437; DBR1_CAEEL; NM_059467; WBGene00000937; WP:CE30437 WormBase description: dbr-1 encodes a homolog of the RNA lariat-debranching enzyme; DBR-1 is predicted to function in RNA processing by hydrolyzing the 2'-5' phosphodiester bond at the branchpoint of excised lariat intron RNA, thus converting the introns into linear molecules that can subsequently be degraded by exonucleases; in C. elegans, DBR-1 activity is required for embryonic and germline development, as well as for normal rates of postembryonic growth; overexpression of C. elegans DBR-1 in Saccharomyces cerevisiae can complement the RNA processing defects of a dbr1 null mutant strain, restoring debranching activity and intron degradation to near wild-type levels. WormBase CDS description: lariat debranching enzyme
C55B7.9 C55B7.9 P W All gene names: mdt-18; C55B7.9; C55B7.9.1; C55B7.9.2; 1H70; CE09020; NM_059468; Q966M5_CAEEL; WBGene00007018; WP:CE09020
C55C3.4 C55C3.4 P W All gene names: C55C3.4; 4G442; CE06991; WBGene00016954; WP:CE06991 WormBase description: tyrosine-protein kinase
C55H1.2 C55H1.2 P W All gene names: gpa-10; C55H1.2; 5H334; CE27889; GPA10_CAEEL; NM_072344; WBGene00001672; WP:CE27889 WormBase description: gpa-10 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADF, ASI, ASJ, ALN, CAN, LUA, and the spermatheca. WormBase CDS description: guanine nucleotide-binding protein
C56A3.6 C56A3.6 P W All gene names: C56A3.6; 5O34; CE32339; WBGene00008345; WP:CE32339 WormBase description: EF hand (2 domains)
C56A3.7 C56A3.7 P W All gene names: cav-2; C56A3.7; 5O39; CAV2_CAEEL; CE15738; NM_073956; WBGene00000302; WP:CE15738 WormBase description: cav-2 encodes one of two C. elegans proteins related to caveolins, integral transmembrane proteins that are believed to function in regulation of signal transduction and that are the major component of caveolae, specialized lipid rafts found in the plasma membrane of most cell types; as loss of cav-2 function via large-scale RNA-mediated interference (RNAi) screens does not result in any obvious abnormalities, the role of cav-2 in C. elegans development and/or behavior is not yet known; cav-2 mRNA is expressed in eggs and mixed stage populations. WormBase CDS description: Caveolin
C56A3.8 C56A3.8 P W All gene names: C56A3.8; 5O41; CE39909; WBGene00008346; WP:CE39909
C56C10.10 C56C10.10 P W All gene names: C56C10.10; 2G884; CE02564; WBGene00016966; WP:CE02564 WormBase description: TPR domain
C56C10.3 C56C10.3 P W All gene names: phi-27; tag-309; C56C10.3; C56C10.3.1; C56C10.3.2; 2G881; CE02568; WBGene00016961; WP:CE02568
C56C10.8 C56C10.8 P W All gene names: icd-1; C56C10.8; C56C10.8.1; C56C10.8.2; 2G878; BTF3_CAEEL; CE02573; NM_062935; WBGene00002045; WP:CE02573 WormBase description: Transcription factor BTF3 (human)
C56E6.1 C56E6.1 P W All gene names: tag-177; C56E6.1; 2G823; CE04273; WBGene00006522; WBGene00016969; WP:CE04273
C56G2.6 C56G2.6 P W All gene names: dhs-10; let-767; C56G2.6; C56G2.6.1; C56G2.6.2; 3H428; CE30639; LE767_CAEEL; NM_065985; WBGene00002891; WP:CE30639 WormBase description: let-767 encodes a short-chain dehydrogenase, reported to be required for efficient cholesterol metabolism; LET-767 is predicted to be required for the metabolism of a sterol and to be mitochondrial.
C56G7.3 C56G7.3 P W All gene names: C56G7.3; 3E481; CE17608; WBGene00008348; WP:CE17608; YQL3_CAEEL
D1007.16 D1007.16 P W All gene names: D1007.16; 1F171; CE23617; WBGene00017011; WP:CE23617
D1009.5 D1009.5 P W All gene names: dylt-2; xbx-2; D1009.5; CE04289; NM_077110; WBGene00017014; WP:CE04289; XJ558
D1014.5 D1014.5 P W All gene names: D1014.5; 5I605; CE07007; WBGene00017018; WP:CE07007
D1022.1 D1022.1 P W All gene names: ubc-6; D1022.1; 2H771; CE29241; CE39712; NM_063165; WBGene00006703; WP:CE29241; WP:CE39712 WormBase description: Ubiquitin-conjugating enzyme
D1025.2 D1025.2 P W All gene names: D1025.2; CE17610; WBGene00008354; WP:CE17610; XP132
D1043.1 D1043.1 P W All gene names: D1043.1; 2L877; CE32842; WBGene00008361; WP:CE32842
D1044.8 D1044.8 P W All gene names: D1044.8; 3G604; CE39141; NEK1_CAEEL; WBGene00017033; WP:CE39141
D1081.2 D1081.2 P W All gene names: unc-120; D1081.2; 1J37; CE05534; NM_059895; WBGene00006844; WP:CE05534 WormBase description: unc-120 encodes a member of the MADS-box family of transcription factors that is most closely related to Drosophila blistered and the vertebrate serum response factors (SRFs); UNC-120 is required for locomotion and muscle development and for formation of the normal number of muscle A and I bands; UNC-120 is also required for maintaining wild-type expression levels of the muscle components actin and myosin; UNC-120 is first expressed in the early embryo in body wall muscle precursors and later is expressed in both body wall and vulval muscles. WormBase CDS description: MADS domain
D1081.8 D1081.8 P W All gene names: phi-7; D1081.8; D1081.8.1; D1081.8.2; 1J71; CE05540; WBGene00008386; WP:CE05540 WormBase description: MYB transforming protein
D2007.4 D2007.4 P W All gene names: D2007.4; 3J235; CE00129; WBGene00017044; WP:CE00129; YLM4_CAEEL
D2013.1 D2013.1 P W All gene names: rab-39; D2013.1; 2J612; CE30340; NM_063583; WBGene00004286; WP:CE30340 WormBase description: rab-39 encodes a small, monomeric Rab GTPase that is most closely related to the human and Drosophila Rab39 GTPases; by homology, RAB-39 is predicted to function as a membrane-associated GTPase required for intracellular vesicular trafficking and for regulation of endo- and exocytosis; however, as loss of rab-39 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of RAB-39 in C. elegans development and/or behavior is not yet known. WormBase CDS description: GTP binding protein (YPT1 subfamily)
D2023.6 D2023.6 P W All gene names: D2023.6; 5M309; CE09076; WBGene00008410; WP:CE09076 WormBase description: D2023.6 is orthologous to a set of uncharacterized putative protein kinases from eukaryotes and from prokaryotes (e.g., UbiB from E. coli), and paralogous to COQ-8 from C. elegans and ABC1 (COQ8) from S. cerevisiae; like COQ-8, D2023.6 may be involved in ubiquinone (coenzyme Q9) biosynthesis. WormBase CDS description: Yeast ABC1 protein like
D2024.3 D2024.3 P W All gene names: elo-3; D2024.3; 4I3; CE34783; ELO3_CAEEL; NM_068746; WBGene00001241; WP:CE34783 WormBase description: The elo-3 gene encodes a paralog of elo-1 and elo-2, each of which encodes a polyunsaturated fatty acid (PUFA) elongase; ELO-3 may be required for normally rapid growth.
D2030.4 D2030.4 P W All gene names: D2030.4; D2030.4.1; D2030.4.2; 1I156; CE09081; NDUB7_CAEEL; WBGene00008414; WP:CE09081 WormBase description: D2030.4 encodes the C. elegans ortholog of the NDUFB7/B18 subunit of the mitochondrial NADH dehydrogenase (ubiquinone) complex (complex I). WormBase CDS description: NADH:CoQ oxidoreductase subunit B18
D2085.1 D2085.1 P W All gene names: pyr-1; D2085.1; 2I947; CE03105; NM_063437; WBGene00004259; WP:CE03105 WormBase description: pyr-1 is orthologous to the human gene CARBAMYL PHOSPHATE SYNTHETASE I (CPS1, which when mutated leads to hyperammonemia (OMIM:237300); PYR-1 protein is predicted to be mitochondrial with 68% accuracy. WormBase CDS description: glutamine-dependent carbamoyl-phosphate synthase, aspartate carbamoyltransferase, dihydroorotase
D2085.6 D2085.6 P W All gene names: D2085.6; 2I950; CE03109; WBGene00008431; WP:CE03109 WormBase description: D2085.6 is orthologous to the human gene CLASS A GLCNAC-INOSITOL PHOSPHOLIPID ASSEMBLY PROTEIN (PIGA; OMIM:311770), which when mutated leads to paroxysmal nocturnal hemoglobinuria. WormBase CDS description: phosphatidylinositol biosynthetic protein
D2089.2 D2089.2 P W All gene names: D2089.2; 2K950; CE00937; WBGene00008433; WP:CE00937
DH11.3 DH11.3 P W All gene names: pgp-11; DH11.3; 2I286; CE34788; NM_063273; WBGene00004005; WP:CE34788 WormBase description: pgp-11 encodes an ATP-binding protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; pgp-11 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of pgp-11 activity via large-scale RNAi screens does not result in any obvious defects, the precise role of pgp-11 in C. elegans development and/or behavior is not yet known; pgp-11 promoter-gfp fusion proteins are expressed in the excretory cell and in the intestine. WormBase CDS description: multidrug resistance protein
DY3.7 DY3.7 P W All gene names: sup-17; DY3.7; 1J373; CE15751; NM_059976; WBGene00006324; WP:CE15751 WormBase description: sup-17 encodes an ADAM protein, an integral membrane disintegrin and zinc-activated metalloproteinase, orthologous to Drosophila and mouse KUZBANIAN and the vertebrate ADAM10 proteins; SUP-17 is required maternally for embryonic development and plays a role in LIN-12/Notch-mediated cell signaling required for several cell fate decisions during vulval development; SUP-17 is also required for normal body morphology and male tail development; SUP-17 functions cell autonomously to facilitate LIN-12 signaling and requires the LIN-12 extracellular domain to do so. WormBase CDS description: Zinc-binding metalloprotease domain
E01A2.1 E01A2.1 P W All gene names: E01A2.1; 1E709; CE24869; Q966L2_CAEEL; WBGene00017084; WP:CE24869
E01A2.4 E01A2.4 P W All gene names: E01A2.4; 1E698; CE24871; WBGene00017086; WP:CE24871
E01A2.5 E01A2.5 P W All gene names: E01A2.5; 1E704; CE39095; WBGene00017087; WP:CE39095
E01A2.6 E01A2.6 P W All gene names: E01A2.6; 1E706; CE24873; WBGene00017088; WP:CE24873
E01G6.3 E01G6.3 P W All gene names: E01G6.3; CE09114; WBGene00008451; WP:CE09114; XM861 WormBase description: serine esterase
E02H1.6 E02H1.6 P W All gene names: E02H1.6; 2J887; CE28286; KAD6_CAEEL; WBGene00008458; WP:CE28286 WormBase description: E02H1.6 encodes an ortholog of human TAF9 (OMIM:600822; also known as AK6, adrenal gland protein AD-004 like protein, ADLP) and of S. cerevisiae Fap7p; like its human ortholog, E02H1.6 is nuclear, and is predicted to likewise be a TATA box binding protein (TBP)-associated factor mediating activation of RNA polymerase II; E02H1.6 prefers ATP and dATP as phosphate donors; E02H1.6's biochemical activity is unusual, since it also prefers AMP and dAMP as substrates, and tolerates CMP, TMP and shikimate acid as substrates as well; since yeast Fap7p promotes pre-rRNA cleavage, E02H1.6 may be multifunctional; in RNAi assays, E02H1.6 is required for normally fast growth. WormBase CDS description: ATP binding protein
E03A3.5 E03A3.5 P W All gene names: E03A3.5; 3F153; CE25839; WBGene00008465; WP:CE25839 WormBase description: disulphide bond domain
E03G2.2 E03G2.2 P W All gene names: mrp-3; E03G2.2; CE03119; NM_078215; WBGene00003409; WP:CE03119; XQ550 WormBase description: multidrug resistance-associated protein
E03H4.6 E03H4.6 P W All gene names: NHR-B; nhr-174; E03H4.6; 1N9; CE09133; NH174_CAEEL; WBGene00008474; WP:CE09133 WormBase description: Zinc finger, C4 type (two domains)
E04F6.2 E04F6.2 P W All gene names: E04F6.2; 2H491; CE01214; WBGene00017122; WP:CE01214
EGAP2.3 EGAP2.3 P W All gene names: pho-1; EGAP2.3; EGAP2.3.1; EGAP2.3.2; 2F524; CE04325; NM_062582; WBGene00004020; WP:CE04325 WormBase description: pho-1 encodes the major C. elegans intestinal acid phosphatase; as loss of PHO-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, PHO-1 may function redundantly with other acid phosphatases; PHO-1 intestinal expression appears to be positively regulated by CKI-1, a cyclin-dependent kinase inhibitor, and negatively regulated by POP-1, a TCF/LEF transcription factor; PHO-1 is expressed along the intestinal brush border in all gut cells except the most anterior int-1 and int-2 cells, beginning at the three-fold stage of embryogenesis.
EGAP7.1 EGAP7.1 P W All gene names: dpy-12; dpy-3; EGAP007.1; EGAP7.1; CE07013; NM_075994; WBGene00001065; WP:CE07013; XC764 WormBase description: dpy-3 encodes a cuticular collagen; along with dpy-2, dpy-7, dpy-8, and dpy-10, dpy-3 is required postembryonically for annular furrow formation and/or maintenance; specifically, DPY-3 activity is required for proper assembly of the DPY-7 collagen into the mature extracellular matrix; during each cuticle synthetic period, dpy-3 mRNA is expressed approximately four hours prior to the secretion of new cuticle. WormBase CDS description: cuticular collagen
F01D5.8 F01D5.8 P W All gene names: F01D5.8; 2O303; CE18565; WBGene00008498; WP:CE18565
F01G10.10 F01G10.10 P W All gene names: F01G10.10; 4L13; CE36123; WBGene00008512; WP:CE36123 WormBase description: lipopolysaccharide-binding protein like
F01G4.6 F01G4.6 P W All gene names: F01G4.6; F01G4.6.1; F01G4.6.2; F01G4.6.3; F01G4.6.4; 4L912; CE09162; MPCP_CAEEL; WBGene00008505; WP:CE09162 WormBase description: phosphate carrier protein precursor
F02D10.5 F02D10.5 P W All gene names: flr-1; F02D10.5; CE27118; NM_077842; WBGene00001465; WP:CE27118; XO72 WormBase description: sodium channel like
F02D8.3 F02D8.3 P W All gene names: xbx-1; F02D8.3; 5P459; CE39142; NM_074282; WBGene00006960; WP:CE39142
F02E11.5 F02E11.5 P W All gene names: F02E11.5; 2D572; CE09196; WBGene00017183; WP:CE09196
F02E8.5 F02E8.5 P W All gene names: F02E8.5; CE07020; WBGene00017178; WP:CE07020; XF78; YDEM_CAEEL
F07A11.4 F07A11.4 P W All gene names: F07A11.4; 2L901; CE03146; WBGene00008547; WP:CE03146 WormBase description: ubiquitin carboxyl-terminal hydrolase
F07A5.3 F07A5.3 P W All gene names: F07A5.3; 1H935; CE05556; WBGene00008542; WP:CE05556 WormBase description: membrane glycoprotein
F07E5.5 F07E5.5 P W All gene names: F07E5.5; 2C344; CE27916; WBGene00017210; WP:CE27916 WormBase description: zinc-finger protein
F07H5.9 F07H5.9 P W All gene names: F07H5.9; 2J94; CE35850; WBGene00008560; WP:CE35850 WormBase description: acid phosphatase
F08A8.3 F08A8.3 P W All gene names: F08A8.3; 1N541; CE17635; WBGene00008566; WP:CE17635 WormBase description: ACYL-COENZYME A OXIDASE, PEROXISOMAL (EC 1.3.3.6) (PALMITOYL-COA OXIDASE) (AOX)
F08C6.4 F08C6.4 P W All gene names: sto-1; F08C6.4; CE27924; NM_076880; STO1_CAEEL; WBGene00006063; WP:CE27924; XI183 WormBase description: Erythrocyte band 7 integral membrane protein (human)
F08F1.9 F08F1.9 P W All gene names: F08F1.9; CE09256; WBGene00017259; WP:CE09256; XJ28
F08G12.2 F08G12.2 P W All gene names: F08G12.2; CE18578; Q19211_CAEEL; WBGene00008586; WP:CE18578; XL916 WormBase description: WD domain, G-beta repeat (6 domains)
F08G2.3 F08G2.3 P W All gene names: his-42; F08G2.3; 2O120; NM_064498; WBGene00001916 WormBase description: his-42 encodes an H3 histone. WormBase CDS description: Core histones H2A, H2B, H3 and H4
F08H9.4 F08H9.4 P W All gene names: F08H9.4; 5O946; CE09268; WBGene00008592; WP:CE09268 WormBase description: F08H9.4 encodes a heat shock protein (HSP) of the HSP16 class; unlike most HSP16s in C. elegans, it is specifically expressed in a particular tissue (the excretory canal and ventral nerve-cord neurons), and its expression is only mildly induced by heat shock; however, F08H9.4 expression is increased by heat shock, is induced in a new tissue type (intestine) by heat shock, and probably aids heat shock resistance, since F08H9.4(RNAi) animals die as embryos in heat shock at a higher rate than normal; in general, HSP16 proteins are thought to act as passive ligands for unfolded proteins that keep them safe from aggregation until the proteins can be refolded by a large (ATP-consuming) HSP. WormBase CDS description: heat shock protein
F09C12.8 F09C12.8 P W All gene names: F09C12.8; 2F403; CE32360; WBGene00017279; WP:CE32360
F09E5.15 F09E5.15 P W All gene names: prdx-2; tag-56; F09E5.15; F09E5.15.1; F09E5.15.2; 2F669; CE32361; WBGene00006434; WP:CE32361; ceprx2
F09E5.2 F09E5.2 P W All gene names: F09E5.2; 2F667; CE32364; WBGene00017282; WP:CE32364 WormBase description: AHPC/TSA protein
F09E5.8 F09E5.8 P W All gene names: F09E5.8; 2F641; CE02615; WBGene00017286; WP:CE02615; YU68_CAEEL
F09E8.7 F09E8.7 P W All gene names: acr-1; lev-1; tmr-1; F09E8.7; 4N940; ACH7_CAEEL; CE24888; NM_070133; WBGene00002974; WP:CE24888 WormBase description: lev-1 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR) which, when mutated, confers resistance to levamisole; LEV-1 is required for completely normal locomotion, and forms a cation channel when coexpressed with UNC-38 or UNC-63 and UNC-29; LEV-1 falls into the 'UNC-29' class of nAChR subunits, which includes UNC-29, ACR-2, and ACR-3. WormBase CDS description: acetylcholine receptor
F09G2.2 F09G2.2 P W All gene names: F09G2.2; 5H677; CE37626; WBGene00017311; WP:CE37626
F09G2.3 F09G2.3 P W All gene names: F09G2.3; 5H667; CE32858; WBGene00017312; WP:CE32858 WormBase description: permease
F09G2.9 F09G2.9 P W All gene names: F09G2.9; F09G2.9.1; F09G2.9.2; 5H674; CE09304; WBGene00017317; WP:CE09304
F09G8.3 F09G8.3 P W All gene names: F09G8.3; 3J357; CE24890; RT09_CAEEL; WBGene00017319; WP:CE24890
F10B5.4 F10B5.4 P W All gene names: tub-1; F10B5.4; 2I446; CE29091; NM_063309; TUB1_CAEEL; WBGene00006655; WP:CE29091 WormBase description: tub-1 encodes a tubby homolog that affects fat storage in C. elegans and may function in a parallel pathway with kat-1 to affect lipid accumulation based on genetic analysis; expressed primarily in sensory neurons. WormBase CDS description: Tub family protein tub-1
F10B5.9 F10B5.9 P W All gene names: F10B5.9; 2I447; CE34800; WBGene00008643; WP:CE34800
F10C2.6 F10C2.6 P W All gene names: drs-2; F10C2.6; 5M531; CE31906; NM_073618; WBGene00001095; WP:CE31906 WormBase description: drs-2 encodes a putative aspartyl-tRNA synthetase. WormBase CDS description: aspartyl-tRNA synthetase
F10C2.7 F10C2.7 P W All gene names: F10C2.7; 5M535; CE35459; WBGene00008647; WP:CE35459
F10C5.1 F10C5.1 P W All gene names: apc-8; mat-3; pod-4; vex-2; F10C5.1; F10C5.1.1; F10C5.1.2; 3B99; CE26888; NM_064802; Q19294_CAEEL; WBGene00003134; WBGene00006909; WP:CE26888
F10D2.7 F10D2.7 P W All gene names: ugt-38; F10D2.7; 5H618; CE09318; WBGene00017333; WP:CE09318 WormBase description: 7TM chemoreceptor, ugt family
F10D7.3 F10D7.3 P W All gene names: F10D7.3; CE29754; WBGene00017340; WP:CE29754; XR988; YZ73_CAEEL WormBase description: glutaredoxin
F10E9.11 F10E9.11 P W All gene names: F10E9.11; 3J408; CE29491; WBGene00017360; WP:CE29491
F10F2.9 F10F2.9 P W All gene names: pqn-29; F10F2.9; 3F730; CE00954; NM_065547; WBGene00004118; WP:CE00954 WormBase description: The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
F10G7.4 F10G7.4 P W All gene names: rad-21.1; coh-2; scc-1; F10G7.4; 2E989; CE02628; NM_062435; Q19325_CAEEL; WBGene00004737; WP:CE02628 WormBase description: scc-1 encodes a member of the Rad21/Rec8-like family of cohesion proteins that affects embryonic viability, fertility, the rate of embryonic cell divisions and the incidence of male progeny; interacts with ATL-1, F56D12.5, and F11E6.1 based on yeast two-hybrid assays, and is expressed in nondividing embryonic and germline nuclei. WormBase CDS description: DNA double-strand break repair
F10G8.1 F10G8.1 P W All gene names: F10G8.1; 1K595; CE36642; WBGene00008661; WP:CE36642 WormBase description: protein-tyrosine phosphatase
F10G8.4 F10G8.4 P W All gene names: F10G8.4; 1K599; CE09339; WBGene00008663; WP:CE09339 WormBase description: eak-6 encodes a protein tyrosine phosphatase paralogous to SDF-9; eak-6 acts in parallel to akt-1 to regulate insulin-like signaling and dauer formation; EAK-6 is expressed in the neuroendocrine XXXL/R cells, where it localizes to the plasma membrane. WormBase CDS description: protein-tyrosine phosphatase
F11A5.12 F11A5.12 P W All gene names: dod-10; stdh-2; F11A5.12; 5Q705; CE15790; DHBX_CAEEL; NM_074691; WBGene00008678; WP:CE15790 WormBase description: Estradiol 17-beta-dehydrogenase
F11A5.3 F11A5.3 P W All gene names: F11A5.3; 5Q673; CE15781; WBGene00008671; WP:CE15781 WormBase description: RAS related protein
F11C3.2 F11C3.2 P W All gene names: cof-1; ofm-1; unc-122; F11C3.2; 1P467; CE20668; NM_061197; WBGene00006845; WP:CE20668 WormBase description: unc-122 encodes a predicted type II transmembrane protein with extracellular collagen-like domains and a highly conserved olfactomedin (OLF) domain that is found in a family of secreted proteins involved in formation and function of nervous systems; UNC-122 is required for proper locomotion and for normal morphology of the DVB motorneuron, and may regulate neuromuscular function by acting in an aminergic/peptidergic pathway parallel to cholinergic neurotransmission; although mosaic analysis indicates that UNC-122 activity is required in muscle cells, the precise expression and localization patterns of UNC-122 are not yet known.
F11G11.11 F11G11.11 P W All gene names: col-20; F11G11.11; 2F160; CE36533; NM_062478; P91249_CAEEL; WBGene00000609; WP:CE36533 WormBase description: col-20 encodes a collagen; its expression pattern and mutant phenotypes are unknown. WormBase CDS description: collagen
F11G11.2 F11G11.2 P W All gene names: gst-7; F11G11.2; 2F173; CE07055; GST7_CAEEL; NM_062482; WBGene00001755; WP:CE07055 WormBase description: gst-7 encodes a predicted glutathione S-transferase. WormBase CDS description: glutathione S-transferase
F13A7.1 F13A7.1 P W All gene names: F13A7.1; 5Q856; CE15808; WBGene00008724; WP:CE15808
F13B12.2 F13B12.2 P W All gene names: F13B12.2; 4L190; CE37346; WBGene00008730; WP:CE37346 WormBase description: glucose tranporter like
F13B9.5 F13B9.5 P W All gene names: ksr-1; sar-2; sur-3; F13B9.5; F13B9.5.1; F13B9.5.2; CE25854; NM_076995; WBGene00002239; WP:CE25854; XI901
F13D2.2 F13D2.2 P W All gene names: F13D2.2; CE03194; WBGene00008736; WP:CE03194; XL801 WormBase description: G-protein coupled receptor
F13E6.2 F13E6.2 P W All gene names: F13E6.2; CE31475; WBGene00008746; WP:CE31475; XL288 WormBase description: adenylate kinase like
F13E9.8 F13E9.8 P W All gene names: F13E9.8; 4L650; CE05610; WBGene00008757; WP:CE05610
F13G3.4 F13G3.4 P W All gene names: dylt-1; F13G3.4; 1H876; CE17659; NM_059662; Q19416_CAEEL; WBGene00008764; WP:CE17659
F13G3.5 F13G3.5 P W All gene names: F13G3.5; F13G3.5.1; F13G3.5.2; 1H878; CE29761; IMPA1_CAEEL; WBGene00008765; WP:CE29761 WormBase description: myo-inositol-1-monophosphatase
F13G3.7 F13G3.7 P W All gene names: F13G3.7; F13G3.7b.1; F13G3.7b.2; 1H881; CE31477; CE37822; WBGene00008767; WP:CE31477; WP:CE37822 WormBase description: Yeast mitochondrial carrier protein like
F13H10.4 F13H10.4 P W All gene names: F13H10.4; 4L782; CE05625; GCS1_CAEEL; WBGene00008775; WP:CE05625 WormBase description: F13H10.4 is orthologous to the human gene A-GLUCOSIDASE I (GCS1; OMIM:601336), which when mutated leads to disease.
F13H10.5 F13H10.5 P W All gene names: F13H10.5; 4L755; CE35475; WBGene00008776; WP:CE35475
F13H6.1 F13H6.1 P W All gene names: F13H6.1; 5G841; CE30755; WBGene00017430; WP:CE30755 WormBase description: zinc-finger protein
F13H8.2 F13H8.2 P W All gene names: F13H8.2; 2G563; CE27127; WBGene00017435; WP:CE27127 WormBase description: beta transducin Trp-Asp domains
F14A5.1 F14A5.1 P W All gene names: nhr-264; F14A5.1; 4K54; CE05626; WBGene00008778; WP:CE05626 WormBase description: Zinc finger, C4 type (two domains)
F14D12.5 F14D12.5 P W All gene names: sulp-2; F14D12.5; CE27963; NM_076543; WBGene00017464; WP:CE27963; XG216 WormBase description: sulp-2 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-2 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids and when expressed in Xenopus oocytes, SULP-2 does exhibit modest uptake of sulfate; a SULP-2::GFP fusion is expressed in the intestine and rectal gland cells, where it localizes to the basolateral membrane and in cephalic and deirid neurons, where it localizes to sensillar endings. WormBase CDS description: sulfate transporter
F14E5.2 F14E5.2 P W All gene names: F14E5.2; 2I714; CE03205; CE36926; GSLG1_CAEEL; WBGene00008800; WP:CE03205; WP:CE36926 WormBase description: cysteine-rich fibroblast growth factor receptor
F14E5.3 F14E5.3 P W All gene names: F14E5.3; 2I726; CE28915; WBGene00008801; WP:CE28915 WormBase description: Histidine acid phosphatase
F14E5.6 F14E5.6 P W All gene names: F14E5.6; 2I724; CE28916; WBGene00008804; WP:CE28916 WormBase description: Histidine acid phosphatase
F14H12.1 F14H12.1 P W All gene names: col-165; F14H12.1; CE07061; NM_076346; WBGene00000738; WP:CE07061; XE973 WormBase description: cuticular collagen
F14H8.1 F14H8.1 P W All gene names: obr-2; F14H8.1; 5P492; CE35859; NM_074294; WBGene00008832; WP:CE35859 WormBase description: oxysterol-binding protein
F15A4.9 F15A4.9 P W All gene names: F15A4.9; 2M770; CE15846; WBGene00008843; WP:CE15846
F15B10.1 F15B10.1 P W All gene names: F15B10.1; 4H370; CE16987; CE39241; WBGene00017480; WP:CE16987; WP:CE39241 WormBase description: The F15B10.1 gene encodes an ortholog of the Kluyveromyces lactis UDP-N-acetylglucosamine (UPD-GlcNAc) transporter; when expressed in human cells deficient for GDP-fucose transport into the Golgi, F15B10.1 is able to weakly restore such transport (with ~10% efficiency).
F15B9.7 F15B9.7 P W All gene names: cdh-6; F15B9.7; 5N513; CE37969; NM_073855; WBGene00000398; WP:CE37969 WormBase description: cdh-6 encodes a cadherin homolog, with a domain resembling seven transmembrane-sequence receptors, that may be orthologous to the Drosophila cadherin STAN; both CDH-6 and STAN are homologous to secretin-type receptors, have extracellular domains of similar lengths and domain compositions (with similar numbers of cadherin, EGF, laminin G, GFS, and HormR domains); however, the cytoplasmic domains of CDH-6 and STAN are dissimilar. WormBase CDS description: cadherin
F15C11.1 F15C11.1 P W All gene names: sem-4; F15C11.1; F15C11.1.1; F15C11.1.2; 1H623; CE17673; NM_059596; Q17396_CAEEL; WBGene00004773; WP:CE17673 WormBase description: Zinc finger, C2H2 type (7 domains)
F15E6.6 F15E6.6 P W All gene names: F15E6.6; 4F44; CE27966; WBGene00017487; WP:CE27966 WormBase description: xanthine dehydrogenase
F16B12.2 F16B12.2 P W All gene names: dsl-4; F16B12.2; CE09426; NM_077945; WBGene00001106; WP:CE09426; XO709 WormBase description: dsl-4 encodes a putative secreted protein with a single DSL domain and three EGF domains in series, somewhat like Delta/LAG-2; unlike the nematode-specific family of Delta/LAG-2-like proteins (including DSL-1, -2, -3, -5, -6, and -7), DSL-4 is evolutionarily divergent, with perhaps a distant affinity to APX-1, ARG-1, and LAG-2. WormBase CDS description: APX-1 like protein
F16B4.6 F16B4.6 P W All gene names: F16B4.6; 5C67; CE27969; WBGene00017508; WP:CE27969 WormBase description: acy carrier protein
F16F9.4 F16F9.4 P W All gene names: F16F9.4; CE09443; WBGene00017515; WP:CE09443; XJ80 WormBase description: lipase
F16H11.5 F16H11.5 P W All gene names: nhr-45; F16H11.5; CE33052; NM_076396; Q19496_CAEEL; WBGene00003635; WP:CE33052; XF276 WormBase description: zinc finger DNA-binding protein
F16H9.2 F16H9.2 P W All gene names: nhr-27; F16H9.2; CE05645; WBGene00008901; WP:CE05645; XN322 WormBase description: Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains)
F17A2.5 F17A2.5 P W All gene names: ceh-40; F17A2.5; CE03215; HM40_CAEEL; NM_077659; WBGene00000461; WP:CE03215; XM934 WormBase description: ceh-40 encodes one of two C. elegans homeodomain proteins homologous to Extradenticle (Exd/Pbx); ceh-40 genetically interacts with ceh-20 and unc-62 during embryonic development: while loss of ceh-40 activity alone results in no significant embryonic lethality, loss of ceh-40 and ceh-20, or ceh-40, ceh-20, and unc-62, results in incompletely penetrant embryonic lethality. WormBase CDS description: Homeobox domain
F17B5.1 F17B5.1 P W All gene names: F17B5.1; 1N779; CE15865; WBGene00008905; WP:CE15865
F17E9.8 F17E9.8 P W All gene names: F17E9.8; 4J107; CE07074; WBGene00017544; WP:CE07074
F18A11.1 F18A11.1 P W All gene names: puf-6; F18A11.1; 2N330; CE09451; NM_064372; WBGene00004242; WP:CE09451 WormBase description: The puf-6 gene encodes a predicted RNA binding protein that is a member of the conserved PUF (Pumilio and FBF) family of RNA binding proteins; PUF-6 appears to function redundantly with other PUF family members during primordial germ cell development, and interacts with GEX-3, a predicted transmembrane protein that is essential for embryonic tissue morphogenesis. WormBase CDS description: Pumilio-family RNA binding domains (aka PUM-HD, Pumilio homology domain) (6 domains)
F18C12.1 F18C12.1 P W All gene names: avr-1; caf-2; che-3; che-8; osm-2; F18C12.1; 1I638; CE32386; NM_059820; WBGene00000485; WP:CE32386 WormBase description: The dynein heavy chain (DHC) 1b isoform that affects the establishment and maintainance of the structural integrity of sensory cilia and also has a role in intraflagellar transport; it is expressed in ciliated sensory neurons. WormBase CDS description: dynein heavy chain
F18C5.3 F18C5.3 P W All gene names: tag-184; F18C5.3; 2G843; CE02652; WBGene00007050; WBGene00017558; WP:CE02652
F18F11.5 F18F11.5 P W All gene names: F18F11.5; 4B83; CE33621; WBGene00017578; WP:CE33621
F19C7.4 F19C7.4 P W All gene names: F19C7.4; 4F365; CE34540; WBGene00017594; WP:CE34540 WormBase description: lysosomal carboxypeptidase
F19D8.1 F19D8.1 P W All gene names: F19D8.1; CE19800; NM_061932; NM_077904; WBGene00006676; WP:CE19800; XO436 WormBase description: twk-23 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; the precise role of TWK-23 in C. elegans development and/or behavior is not yet known, however TWK-23 may function redundantly with other TWK channels; TWK-23 is expressed in neurons, muscle, the posterior intestine, and diffusely in many other tissues. WormBase CDS description: potassium channel protein
F19H6.1 F19H6.1 P W All gene names: F19H6.1; CE31484; WBGene00008956; WP:CE31484; XN8 WormBase description: serine/threonine kinase
F19H8.3 F19H8.3 P W All gene names: arl-3; F19H8.3; 2O895; ARL3_CAEEL; CE15872; NM_064636; WBGene00000188; WP:CE15872 WormBase description: arl-3 encodes a member of the ARL (ADP-ribosylation factor(ARF)-like) family of proteins which are very similar to ARF proteins but lack the ability to stimulate ADP ribosylation by cholera toxin; as loss of arl-3 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of ARL-3 is not yet known. WormBase CDS description: ADP-ribosylation factors (Arf family) (contains ATP/GTP binding P-loop)
F20B4.7 F20B4.7 P W All gene names: F20B4.7; WBGene00017626; XS300
F20D1.1 F20D1.1 P W All gene names: F20D1.1; F20D1.1.1; F20D1.1.2; CE09494; Q93533_CAEEL; WBGene00008973; WP:CE09494; XP588
F20D1.2 F20D1.2 P W All gene names: F20D1.2; CE31485; WBGene00008974; WP:CE31485; XP593
F20D12.2 F20D12.2 P W All gene names: F20D12.2; 4I717; CE04432; WBGene00017642; WP:CE04432
F20D12.3 F20D12.3 P W All gene names: bbs-2; F20D12.3; 4I701; CE04433; NM_068924; WBGene00000242; WP:CE04433 WormBase description: bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
F20D12.4 F20D12.4 P W All gene names: czw-1; F20D12.4; F20D12.4.1; F20D12.4.2; F20D12.4.3; 4I708; CE04434; NM_068926; WBGene00017643; WP:CE04434
F20D6.6 F20D6.6 P W All gene names: F20D6.6; 5I641; CE07111; WBGene00017636; WP:CE07111 WormBase description: serine/threoninie protein phophatase
F20G4.3 F20G4.3 P W All gene names: nmy-2; F20G4.3; 1I504; CE27133; NM_059785; Q19658_CAEEL; WBGene00003777; WP:CE27133 WormBase description: nmy-2 encodes a maternally expressed nonmuscle myosin II required for polarized cytoplasmic flow, polarized distribution of the PAR proteins, cytokinesis, and for proper anterior-posterior polarity in early embryos; NMY-2 functions with PAR-5 in the onset of the establishment phase of polarization in the C. elegans zygote along the anterior-posterior axis, and nmy-2 is partially redundant with nmy-1 with respect to embryonic elongation; localization of NMY-2 is dynamic in oocytes and embryos. WormBase CDS description: myosin heavy chain
F20H11.1 F20H11.1 P W All gene names: F20H11.1; 3H680; CE29769; WBGene00017646; WP:CE29769
F21A3.2 F21A3.2 P W All gene names: F21A3.2; 5Q12; CE31909; WBGene00008992; WP:CE31909 WormBase description: acid phosphatase
F21C10.12 F21C10.12 P W All gene names: F21C10.12; 5J580; CE32868; WBGene00017661; WP:CE32868
F21D5.2 F21D5.2 P W All gene names: F21D5.2; F21D5.2.1; F21D5.2.2; 4J493; CE03245; WBGene00009007; WP:CE03245 WormBase description: Yeast YHB3-like protein
F21D5.5 F21D5.5 P W All gene names: F21D5.5; 4J500; CE27135; WBGene00009010; WP:CE27135; YZR5_CAEEL WormBase description: polynucleotide kinase 3' phosphatase
F21F8.4 F21F8.4 P W All gene names: F21F8.4; F21F8.4.1; F21F8.4.2; 5I751; CE09540; WBGene00017678; WP:CE09540 WormBase description: protease
F21F8.7 F21F8.7 P W All gene names: asp-6; F21F8.7; F21F8.7.1; F21F8.7.2; 5I748; CE09542; NM_072732; O01530_CAEEL; WBGene00000219; WP:CE09542 WormBase description: aspartic protease. WormBase CDS description: protease
F21H11.3 F21H11.3 P W All gene names: sdf-13; tbx-2; F21H11.3; F21H11.3.1; F21H11.3.2; 3G222; CE01245; NM_065687; TBX2_CAEEL; WBGene00006543; WP:CE01245 WormBase description: tbx-2 encodes one of 21 C. elegans T-box transcription factors; during development, tbx-2 activity is required for normal adaptation, but not chemotaxis, to attractive odorants sensed by the AWC amphid neurons; tbx-2 is also required redundantly with unc-3 and unc-31 for negative regulation of dauer formation, and large-scale RNAi screens reveal an essential role for tbx-2 in early larval development, normal rates of postembryonic growth, and locomotory behavior; antibodies to TBX-2 detect expression in the cytoplasm of amphid and pharyngeal neurons in larvae and adults, suggesting that TBX-2 function may be controlled, in part, by regulation of its subcellular localization; in addition, in situ hybridization studies indicate that tbx-2 mRNA is expressed during mid-embryogenesis; tbx-2 expression in the AWC amphid neurons is sufficient to rescue the olfactory adaptation defects seen in tbx-2 mutant animals.
F21H12.1 F21H12.1 P W All gene names: F21H12.1; 2G389; CE32634; WBGene00017683; WP:CE32634; YQS1_CAEEL
F21H12.5 F21H12.5 P W All gene names: fbf-2; F21H12.5; 2G380; CE01916; FBF2_CAEEL; NM_062819; WBGene00001402; WP:CE01916 WormBase description: fbf-2 encodes an RNA-binding protein that is one of 11 C. elegans members of the PUF family (Pumilio and FBF) of translational regulators; FBF-2 is nearly identical to FBF-1 with which it is largely redundant in regulating two aspects of germline development: 1)maintenance of stem cell proliferation, and 2)the hermaphroditic switch between spermatogenesis and oogenesis; in maintaining germline stem cells, the FBF proteins, acting through NOS-3, negatively regulate the activity of gld-1 mRNA, which encodes a translational repressor required for meiotic entry; in regulating the sperm-to-oocyte switch, the FBFs act downstream of GLD-3 to negatively regulate the activity of fem-3 mRNA, which encodes a novel protein required for germline sex determination; consistent with their role in germline development, FBF-1 and FBF-2 are expressed in the germline cytoplasm, becoming enriched in the mitotic region during the L4 larval and adult stages.
F22A3.3 F22A3.3 P W All gene names: glr-8; F22A3.3; CE27990; NM_076696; WBGene00001619; WP:CE27990; XH127 WormBase description: glr-8 encodes a highly divergent putative ionotropic glutamate receptor subunit, unclassifiable as NMDA or non-NMDA (though possibly of the Delta subfamily), and without any clear close homologs in metazoa or plants; glr-8 is expressed in the pharyngeal nervous system, the body wall mechanoreceptors ALM and PLM, and two other neurons (BDU and URB); glr-8 is expressed from embryogenesis to adulthood. WormBase CDS description: glutamate receptor
F22B3.2 F22B3.2 P W All gene names: his-63; F22B3.2; 4M170; H3_CAEEL; NM_069752; WBGene00001937 WormBase description: his-63 encodes an H3 histone; by homology, HIS-63 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-63 is a replication-dependent histone locus. WormBase CDS description: histone H3
F22B3.8 F22B3.8 P W All gene names: F22B3.8; 4M186; CE35502; WBGene00009039; WP:CE35502 WormBase description: tyrosine-protein kinase
F22B5.1 F22B5.1 P W All gene names: arf-2; evl-20; F22B5.1; 2I735; ARF/2; ARFM_CAEEL; CE27425; NM_063378; WBGene00001358; WP:CE27425 WormBase description: evl-20 encodes a functional ortholog of human ADP-ribosylation factor-like protein 2 (ARL2; OMIM:601175), with evl-20(ar103) mutants being rescued by transgenic human ARL2 but not ARL1 or ARL3-7; EVL-20 is required for cortical microtubule formation during cytokinesis and morphogenesis; EVL-20 is required for vulval, gonadal, and male tail development, as well as for embryonic mitosis, hypodermal enclosure, and elongation; EVL-20 is expressed in migrating hypodermal embryonic cells, larval vulval and somatic gonad cells, larval and adult neurons, and adult male proctodeal cells, being subcellularly associated with both the cell cortex and astral microtubules. WormBase CDS description: GTP-binding ADP-ribosylation factor
F22D3.2 F22D3.2 P W All gene names: F22D3.2; 2H237; CE27138; CE37006; CE37762; WBGene00017699; WP:CE27138; WP:CE37006; WP:CE37762 WormBase description: F22D3.2 encodes an ortholog of human folliculin (OMIM:607273, mutated in Birt-Hogg-Dube syndrome).
F22E10.5 F22E10.5 P W All gene names: F22E10.5; CE05695; WBGene00009057; WP:CE05695; XN383 WormBase description: phosphotransferase
F22E12.1 F22E12.1 P W All gene names: F22E12.1; 5K934; CE31911; WBGene00009058; WP:CE31911
F22E12.2 F22E12.2 P W All gene names: chw-1; F22E12.2; 5K943; CE05696; NM_073285; Q19739_CAEEL; WBGene00009059; WP:CE05696 WormBase description: RAS related protein
F22F1.2 F22F1.2 P W All gene names: F22F1.2; CE04444; WBGene00017714; WP:CE04444; XI770 WormBase description: ser/thr protein kinase
F22F7.2 F22F7.2 P W All gene names: F22F7.2; CE17692; WBGene00017720; WP:CE17692
F23B12.8 F23B12.8 P W All gene names: bmk-1; klp-14; F23B12.8; F23B12.8.1; F23B12.8.2; 5O934; CE09600; NM_074181; Q9XTM0_CAEEL; WBGene00000257; WP:CE09600 WormBase description: a homolog of BimC kinesin; affects embryogenesis, spindle and chromosome positioning during early embryogenesis, and genetically interacts with air-2. WormBase CDS description: kinesin-like protein
F23B2.6 F23B2.6 P W All gene names: aly-2; ref-2; F23B2.6; 4J913; CE09586; NM_069193; WBGene00000121; WP:CE09586 WormBase description: vimentin like
F23C8.7 F23C8.7 P W All gene names: F23C8.7; F23C8.E; 1C990; CE20716; WBGene00017736; WP:CE20716 WormBase description: protein kinase
F23F1.1 F23F1.1 P W All gene names: F23F1.1; CE27996; WBGene00017742; WP:CE27996
F23H11.3 F23H11.3 P W All gene names: F23H11.3; F23H11.3.1; F23H11.3.2; 3B518; CE09611; WBGene00017759; WP:CE09611 WormBase description: succinyl-CoA ligase
F23H12.1 F23H12.1 P W All gene names: snb-2; F23H12.1; 5M824; CE27756; NM_073692; WBGene00004898; WP:CE27756 WormBase description: synaptobrevin like
F25B3.1 F25B3.1 P W All gene names: F25B3.1; 5K35; CE05711; WBGene00009098; WP:CE05711 WormBase description: actin binding domain
F25B3.3 F25B3.3 P W All gene names: F25B3.3; 5K36; CE34003; Q19770_CAEEL; WBGene00009100; WP:CE34003 WormBase description: phorbol ester and DAG binding domain
F25B4.2 F25B4.2 P W All gene names: F25B4.2; 5G191; CE30760; PELLINO; WBGene00017766; WP:CE30760
F25B4.5 F25B4.5 P W All gene names: F25B4.5; F25B4.5.1; F25B4.5.2; 5G160; CE28000; WBGene00017768; WP:CE28000
F25B5.5 F25B5.5 P W All gene names: F25B5.5; 3H34; CE01922; CK5P1_CAEEL; WBGene00017776; WP:CE01922
F25F8.2 F25F8.2 P W All gene names: avm-2; glc-2; F25F8.2; 1F454; CE09636; GLUCB_CAEEL; NM_059069; WBGene00001592; WP:CE09636 WormBase description: glc-2 encodes the beta subunit of a glutamate-gated chloride channel; in vivo, GLC-2 is capable of forming homomeric glutamate-activated channels, as well as heteromeric channels with GLC-1 that can be activated by glutamate and avermectins, antihelmintics that inhibit pharyngeal pumping; as loss of glc-2 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of GLC-2 in development and/or behavior is not yet known; however, GLC-2 expression is generally restricted to the pm4 pharyngeal muscles of larvae and adults, suggesting a role for GLC-2 in regulation of glutamatergic inhibition of pharyngeal pumping. WormBase CDS description: glutamate-gated chloride channel protein
F25G6.8 F25G6.8 P W All gene names: F25G6.8; F25G6.8.1; F25G6.8.2; 5J44; CE09644; SRP14_CAEEL; WBGene00017799; WP:CE09644
F25H2.9 F25H2.9 P W All gene names: pas-5; F25H2.9; 1L143; CE09654; NM_060364; PSA5_CAEEL; WBGene00003926; WP:CE09654 WormBase description: proteasome zeta chain
F26B1.7 F26B1.7 P W All gene names: let-381; F26B1.7; 1G898; CE28006; NM_059425; WBGene00002601; WP:CE28006 WormBase description: let-381 encodes a forkhead transcription factor and was identified in a screen for essential genes; let-381 is essential for development at different times as mutants exhibit embryonic and early larval lethality, with a few developing to sterile adults; inactivation of let-381 using RNA interference results in adults with mesodermal cell lineage defects and a reduced number of coelomocytes; reporter-gene assays indicate LET-318 is expressed when the embryo starts to elongate and continues to be expressed through all larval stages and into the adult. WormBase CDS description: fork-head domain-type transcription factors
F26C11.1 F26C11.1 P W All gene names: F26C11.1; 2K187; CE05732; PPAX_CAEEL; WBGene00009146; WP:CE05732 WormBase description: acid phosphatase
F26C11.3 F26C11.3 P W All gene names: F26C11.3; 2K194; CE37833; WBGene00009147; WP:CE37833; YQU3_CAEEL WormBase description: Sushi domain
F26D10.3 F26D10.3 P W All gene names: hsp-1; F26D10.3; F26D10.3.1; F26D10.3.2; F26D10.3.3; T28F3.2; 4S223; CE09682; HSP7A_CAEEL; NM_070667; WBGene00002005; WP:CE09682 WormBase description: hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regulation of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity. WormBase CDS description: HSP-1 heat shock 70kd protein A
F26E4.11 F26E4.11 P W All gene names: F26E4.11; F26E4.11.1; F26E4.11.2; 1K371; CE09695; WBGene00009164; WP:CE09695; YUES_CAEEL WormBase description: Zinc finger, C3HC4 type (RING finger)
F26E4.8 F26E4.8 P W All gene names: tba-1; F26E4.8; F26E4.8.1; F26E4.8.2; 1K362; CE09692; NM_060199; O18688_CAEEL; TUBA3; WBGene00006528; WP:CE09692 WormBase description: TBA-2 tubulin alpha-2 chain
F26E4.9 F26E4.9 P W All gene names: cco-1; lpd-4; F26E4.9; F26E4.9.1; F26E4.9.2; F26E4.9.3; 1K365; CE09693; NM_060200; WBGene00000371; WP:CE09693 WormBase description: cytochrome C oxidase
F26F12.1 F26F12.1 P W All gene names: col-140; F26F12.1; 5G316; CE07146; NM_072124; Q19813_CAEEL; WBGene00000713; WP:CE07146 WormBase description: cuticular collagen
F26F4.12 F26F4.12 P W All gene names: F26F4.12; 3F998; CE28922; WBGene00017831; WP:CE28922
F26F4.4 F26F4.4 P W All gene names: tag-340; F26F4.4; F26F4.4.1; F26F4.4.2; F26F4.4.3; 3F991; CE30767; WBGene00017826; WP:CE30767
F26F4.7 F26F4.7 P W All gene names: nhl-2; F26F4.7; 3F984; CE29291; NM_065625; WBGene00003598; WP:CE29291
F27D4.1 F27D4.1 P W All gene names: F27D4.1; F27D4.1.1; F27D4.1.2; 1I279; CE24926; ETFA_CAEEL; WBGene00009187; WP:CE24926 WormBase description: The F27D4.1 gene encodes an ortholog of the human gene ELECTRON-TRANSFER-FLAVOPROTEIN, ALPHA POLYPEPTIDE (ETFA), which when mutated leads to glutaricaciduria type IIA (OMIM:231680). WormBase CDS description: electron transfer flavoprotein alpha-subunit
F27D9.8 F27D9.8 P W All gene names: stn-2; F27D9.8; CE29779; CE37639; WBGene00017866; WP:CE29779; WP:CE37639; XI296 WormBase description: synapse-associated protein
F28B3.4 F28B3.4 P W All gene names: F28B3.4; CE09742; WBGene00017885; WP:CE09742
F28B4.3 F28B4.3 P W All gene names: F28B4.3; CE07153; WBGene00017892; WP:CE07153; XD846 WormBase description: EGF-like repeat
F28C6.1 F28C6.1 P W All gene names: F28C6.1; 2I881; CE03272; WBGene00009202; WP:CE03272 WormBase description: transcription factor AP-2 like
F28G4.1 F28G4.1 P W All gene names: cyp-37B1; F28G4.1; 5Q759; CE15919; NM_074708; WBGene00009226; WP:CE15919 WormBase description: cytochrome P450
F28H1.3 F28H1.3 P W All gene names: ars-2; F28H1.3; F28H1.3.1; F28H1.3.2; F28H1.3.3; 1E553; CE09768; NM_058880; WBGene00000197; WP:CE09768 WormBase description: ars-2 encodes a predicted cytoplasmic alanyl-tRNA synthetase (AlaRS), a class II aminoacyl-tRNA synthetase that catalyzes the attachment of alanine to its cognate tRNA and is thus required for protein biosynthesis; ARS-2 is essential for embryogenesis, and is required for fertility and a normal rate of postembryonic development; ARS-2 expression is likely ubiquitous and detected in hypodermis, intestine, neurons, and the pharynx from late embryogenesis through the adult stage of development. WormBase CDS description: aminoacyl-tRNA synthetase
F28H6.3 F28H6.3 P W All gene names: F28H6.3; CE18648; WBGene00009232; WP:CE18648; XO760 WormBase description: nkat-1 encodes kynurenine aminotransferase III, an ortholog of mammalian KAT3; nkat-1(RNAi) animals have no obvious phenotype. WormBase CDS description: Aminotransferases class-I
F28H7.4 F28H7.4 P W All gene names: F28H7.4; 5L226; CE36142; SELT2_CAEEL; WBGene00009238; WP:CE36142
F28H7.8 F28H7.8 P W All gene names: F28H7.8; 5L241; CE37900; WBGene00009241; WP:CE37900; YUQP_CAEEL
F29A7.4 F29A7.4 P W All gene names: F29A7.4; 2D41; CE36835; WBGene00017914; WP:CE36835
F29C12.2 F29C12.2 P W All gene names: F29C12.2; 2N388; WBGene00009244
F30B5.7 F30B5.7 P W All gene names: F30B5.7; 4E994; CE28225; WBGene00017936; WP:CE28225
F30F8.8 F30F8.8 P W All gene names: taf-5; F30F8.8; F30F8.8.1; F30F8.8.2; F30F8.8.3; 1I429; CE39361; NM_059768; WBGene00006386; WP:CE39361 WormBase description: guanine nucleotide-binding protein
F31D4.2 F31D4.2 P W All gene names: F31D4.2; 5V312; CE15928; WBGene00009290; WP:CE15928
F31D4.5 F31D4.5 P W All gene names: F31D4.5; 5V327; CE15931; WBGene00009292; WP:CE15931 WormBase description: PH (pleckstrin homology) domain
F31D5.4 F31D5.4 P W All gene names: F31D5.4; 2E480; CE37367; WBGene00017947; WP:CE37367
F31E8.6 F31E8.6 P W All gene names: F31E8.6; 2H106; WBGene00017956
F32A6.2 F32A6.2 P W All gene names: F32A6.2; CE34008; WBGene00017973; WP:CE34008; XF921
F32A6.3 F32A6.3 P W All gene names: vps-41; F32A6.3; CE37009; CE38956; VPS41_CAEEL; WBGene00017974; WP:CE37009; WP:CE38956; XF907
F32A6.5 F32A6.5 P W All gene names: sto-2; F32A6.5; CE33065; NM_076501; STO2_CAEEL; WBGene00006064; WP:CE33065; XF928
F32B6.1 F32B6.1 P W All gene names: nhr-4; F32B6.1; F32B6.1.1; F32B6.1.2; 4K645; CE24934; NHR4_CAEEL; NM_069374; WBGene00003603; WP:CE24934 WormBase description: nhr-4 is predicted to encode a nuclear hormone receptor (NHR); expression may peak during the late larval stages, based on mRNA expression analysis. WormBase CDS description: Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains)
F32B6.3 F32B6.3 P W All gene names: F32B6.3; 4K646; CE35518; WBGene00009320; WP:CE35518 WormBase description: Human HPRP18 protein like
F32B6.9 F32B6.9 P W All gene names: F32B6.9; 4K667; CE09864; WBGene00009323; WP:CE09864; YV4Q_CAEEL WormBase description: Putative membrane protein
F32E10.6 F32E10.6 P W All gene names: F32E10.6; F32E10.6.1; F32E10.6.2; 4I344; CE04479; WBGene00017993; WP:CE04479
F32G8.5 F32G8.5 P W All gene names: col-152; F32G8.5; 5L41; CE05794; NM_073308; WBGene00000725; WP:CE05794 WormBase description: collagen
F32H2.2 F32H2.2 P W All gene names: mdt-31; F32H2.2; 1J543; CE09877; MED31_CAEEL; NM_060012; WBGene00007026; WP:CE09877 WormBase description: Yeast SOH1 protein like
F33A8.9 F33A8.9 P W All gene names: col-83; F33A8.9; 2L336; CE35183; NM_063966; WBGene00000658; WP:CE35183 WormBase description: collagen
F33D4.4 F33D4.4 P W All gene names: F33D4.4; F33D4.4.1; F33D4.4.2; 4I470; CE17034; WBGene00017996; WP:CE17034
F33E11.1 F33E11.1 P W All gene names: nhr-15; F33E11.1; 5A799; CE17759; NM_070773; WBGene00003614; WP:CE17759 WormBase description: nhr-15 is predicted to encode a member of the nuclear hormone receptor family. WormBase CDS description: nuclear hormone receptor
F34D6.3 F34D6.3 P W All gene names: sup-9; twk-23; twk-38; F34D6.3; 2C976; CE28297; SUP9_CAEEL; WBGene00006318; WP:CE28297 WormBase description: sup-9 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; sup-9 was originally defined by gain-of-function mutations that result in defects in pharyngeal, body-wall, egg-laying, and enteric muscle activation; loss of sup-9 function via reversion or RNA-mediated interference (RNAi) does not result in any abnormalities suggesting that SUP-9 may function redundantly with other TWK channels; SUP-9 is expressed in neurons and muscle.
F35C11.4 F35C11.4 P W All gene names: F35C11.4; 2I539; CE03284; WBGene00009403; WP:CE03284
F35C12.2 F35C12.2 P W All gene names: ncx-4; F35C12.2; 1K387; CE28020; NM_060203; WBGene00003569; WP:CE28020 WormBase description: Na/Ca,K exchanger
F35C5.3 F35C5.3 P W All gene names: F35C5.3; 2N179; CE15943; WBGene00009391; WP:CE15943
F35D2.4 F35D2.4 P W All gene names: F35D2.4; 2H866; CE02726; WBGene00018042; WP:CE02726
F35G12.7 F35G12.7 P W All gene names: F35G12.7; 3F676; CE32184; WBGene00009443; WP:CE32184
F35H8.7 F35H8.7 P W All gene names: wee-1.1; F35H8.7; 2J872; CE09940; NM_063657; PMY11_CAEEL; WBGene00006938; WP:CE09940 WormBase description: serine/threonine kinase
F36A2.2 F36A2.2 P W All gene names: F36A2.2; 1J378; CE09942; WBGene00009452; WP:CE09942 WormBase description: Yeast protein 8248 like
F36D3.9 F36D3.9 P W All gene names: cpr-2; F36D3.9; 5R14; CE30347; CPROT/2; NM_074785; WBGene00000782; WP:CE30347 WormBase description: cysteine protease
F36H1.2 F36H1.2 P W All gene names: tag-144; F36H1.2; 4L811; CE05814; CE39931; WBGene00006490; WP:CE05814; WP:CE39931 WormBase description: F36H1.2 encodes a KAP family P-loop predicted NTPase, with two or four transmembrane helices inserted into the P-loop NTPase domain; KAP NTPases include the neuronal membrane protein and receptor tyrosine kinase substrate Kidins220/ARMS (conserved in metazoa) and the F-plasmid PifA protein involved in phage T7 exclusion (with other bacterial homologs being sporadically distributed); F36H1.2 is expressed in several tissues, including intestine, excretory cell, body wall muscle, and various neurons; F36H1.2 is required for persistence of the germline in RNAi assays.
F36H1.6 F36H1.6 P W All gene names: alh-3; F36H1.6; 4L789; CE05817; NM_069653; WBGene00000109; WP:CE05817 WormBase description: alh-3 encodes an aldehyde dehydrogenase predicted to be mitochondrial. WormBase CDS description: formyltetrahydrofolate dehydrogenase
F37A8.5 F37A8.5 P W All gene names: F37A8.5; 3F47; CE23704; WBGene00009503; WP:CE23704; YPL1_CAEEL
F37B1.2 F37B1.2 P W All gene names: gst-12; F37B1.2; 2N906; CE09989; NM_064461; Q93695_CAEEL; WBGene00001760; WP:CE09989 WormBase description: glutathione S-transferase
F37B12.2 F37B12.2 P W All gene names: gcs-1; F37B12.2; F37B12.2.1; F37B12.2.2; 2J326; CE32886; GSH1_CAEEL; NM_063526; WBGene00001527; WP:CE32886 WormBase description: gcs-1 encodes the C. elegans ortholog of gamma-glutamine cysteine synthetase heavy chain (GCS(h)); GCS-1 is predicted to function, in a conserved oxidative stress response pathway, as a phase II detoxification enzyme that catalyzes the rate-limiting first step in glutathione biosynthesis; a GCS-1::GFP reporter fusion is expressed in larvae and adults in the pharynx, ASI chemosensory neurons, and anterior and posterior intestine and upon exposure to oxidative stress, such as heat or herbicide, the intestinal expression increases dramatically; constitutive and stress-inducible GCS-1::GFP expression in the ASI neurons and intestine, respectively, is under the control of the SKN-1 CNC transcription factor; loss of gcs-1 activity via RNAi results in a low percentage of larval lethality and intestinal abnormalities suggesting that gcs-1 plays a role in postembryonic development. WormBase CDS description: glutamate-cysteine ligase
F37C12.4 F37C12.4 P W All gene names: rpl-36; F37C12.4; F37C12.4.1; F37C12.4.2; F37C12.4.3; 3I271; CE30781; NM_066172; RL36_CAEEL; WBGene00004450; WP:CE30781 WormBase description: rpl-36 encodes a large ribosomal subunit L36 protein; by homology, RPL-36 is predicted to function in protein biosynthesis; in C. elegans, RPL-36 activity is required for embryonic and germline development and normal postembryonic growth rates. WormBase CDS description: Ribosomal protein YL39
F37C12.9 F37C12.9 P W All gene names: rps-14; F37C12.9; F37C12.9.1; F37C12.9.2; 3I268; CE00821; NM_066171; RS14_CAEEL; WBGene00004483; WP:CE00821 WormBase description: rps-14 encodes a small ribosomal subunit S14 protein; by homology, RPS-14 is predicted to function in protein biosynthesis; in C. elegans, RPS-14 activity is required for embryonic and germline development, as well as the overall health of the animal. WormBase CDS description: Ribosomal protein S14
F37E3.2 F37E3.2 P W All gene names: F37E3.2; 1H0; CE39017; WBGene00018157; WP:CE39017
F37F2.3 F37F2.3 P W All gene names: gst-25; F37F2.3; 1B922; CE17804; NM_058456; WBGene00001773; WP:CE17804 WormBase description: glutathione S-transferase
F37H8.3 F37H8.3 P W All gene names: F37H8.3; 2L473; CE35870; WBGene00009512; WP:CE35870 WormBase description: haloacid dehalogenase-like hydrolase
F38B6.4 F38B6.4 P W All gene names: F38B6.4; CE28304; WBGene00018174; WP:CE28304; XH297 WormBase description: GARS/AIRS/GART
F38B7.3 F38B7.3 P W All gene names: F38B7.3; 5M31; CE20758; WBGene00009534; WP:CE20758 WormBase description: PH (pleckstrin homology) domain
F38B7.5 F38B7.5 P W All gene names: duo-1; usp-1; F38B7.5; 5M37; CE33394; NM_073530; WBGene00001110; WP:CE33394 WormBase description: Ubiquitin carboxyl-terminal hydrolase
F38E1.9 F38E1.9 P W All gene names: F38E1.9; 5I838; CE04527; MPU1_CAEEL; WBGene00018181; WP:CE04527
F38E11.1 F38E11.1 P W All gene names: hsp-12.3; F38E11.1; 4K208; CE03293; NM_069266; WBGene00002012; WP:CE03293 WormBase description: alpha-B-crystallin
F38E11.12 F38E11.12 P W All gene names: cng-3; F38E11.12; 4K242; CE37910; WBGene00000563; WP:CE37910 WormBase description: cng-3 is predicted to encode a cyclic nucleotide gated (CNG) channel that is required for wild-type thermotolerance; cng-3 is expressed in five sensory neurons, including the thermosensory neuron AFD. WormBase CDS description: cGMP-gated cation channel protein
F38E9.1 F38E9.1 P W All gene names: F38E9.1; CE28305; NM_078272; Q20177_CAEEL; WBGene00018184; WP:CE28305
F38G1.1 F38G1.1 P W All gene names: che-2; F38G1.1; F38G1.1.1; F38G1.1.2; CE25876; NM_075705; WBGene00000484; WP:CE25876; XB103 WormBase description: che-2 encodes a protein that contains G-protein beta-like WD-40 repeats that affects chemotaxis, dauer formation, and longevity; expressed in the cilia of most ciliated sensory neurons, some head neurons, and male tail rays. WormBase CDS description: G-beta-repeats
F38H4.10 F38H4.10 P W All gene names: F38H4.10; 4M625; CE32887; WBGene00009551; WP:CE32887 WormBase description: Yeast hypothetical protein YIK6 like
F38H4.9 F38H4.9 P W All gene names: PP2A-C; let-92; F38H4.9; F38H4.9.1; F38H4.9.2; 4M623; CE10074; NM_069846; Q27498_CAEEL; WBGene00002363; WP:CE10074 WormBase description: let-92 encodes a homolog of PP2AC, the catalytic subunit of protein phosphatase 2A (PP2A), identified genetically in screens for essential genes on chromosome IV; LET-92 may regulate a number of signal transduction pathways as it is required for embryogenesis, larval development, Ras-mediated vulval development, and axonal guidance in the DD and VD neurons; let-92 interacts genetically with sur-6 which encodes a regulatory subunit of PP2A; LET-92 protein is bound both by SMG-2 and by POS-1, and also interacts in vitro with UNC-51 and UNC-14; LET-92 is expressed cytoplasmically in nearly all cells and strongly in many neurons. WormBase CDS description: serine/threonine protein phosphatase
F39B2.6 F39B2.6 P W All gene names: rps-26; F39B2.6; F39B2.6.1; F39B2.6.2; 1P353; CE16012; NM_061170; RS26_CAEEL; WBGene00004495; WP:CE16012 WormBase description: rps-26 encodes a small ribosomal subunit S26 protein; by homology, RPS-26 is predicted to function in protein biosynthesis; in C. elegans, RPS-26 activity is required for embryonic, larval, and germline development, as well as normal locomotion and body morphology. WormBase CDS description: 40S ribosomal protein S26
F39D8.4 F39D8.4 P W All gene names: nas-13; F39D8.4; CE35874; NAS13_CAEEL; NM_078148; WBGene00003532; WP:CE35874; XQ44 WormBase description: metalloprotease
F39F10.2 F39F10.2 P W All gene names: F39F10.2; CE07204; WBGene00018202; WP:CE07204; XR507 WormBase description: serine/threonine-protein kinase
F39F10.3 F39F10.3 P W All gene names: F39F10.3; CE07205; WBGene00018203; WP:CE07205; XR505 WormBase description: serine/threonine-protein kinase
F39G3.1 F39G3.1 P W All gene names: ugt-61; F39G3.1; 5F221; CE30782; WBGene00018206; WP:CE30782 WormBase description: 7TM chemoreceptor, ugt family
F39G3.7 F39G3.7 P W All gene names: pex-6; prx-6; F39G3.7; 5F194; CE10124; NM_071867; WBGene00004195; WP:CE10124 WormBase description: ATPase
F39H11.5 F39H11.5 P W All gene names: pbs-7; F39H11.5; F39H11.5.1; F39H11.5.2; 1J272; CE20761; NM_059953; WBGene00003953; WP:CE20761 WormBase description: pbs-7 encodes a B-type subunit of the 26S proteasome's 20S protease core particle; by homology, PBS-7 is predicted to function in ATP/ubiquitin-dependent nonlysosomal protein degradation; loss of pbs-7 activity via large-scale RNAi screens indicates that, in C. elegans, PBS-7 is required for normal movement and for embryonic, germline, and larval development. WormBase CDS description: Yeast NIP80 protein like
F40A3.3 F40A3.3 P W All gene names: F40A3.3; F40A3.3b.1; F40A3.3b.2; 5I359; CE10146; CE38516; PEBPH_CAEEL; WBGene00018218; WP:CE10146; WP:CE38516 WormBase description: phosphatidylethanolamine binding protein
F40F12.7 F40F12.7 P W All gene names: F40F12.7; F40F12.7.1; F40F12.7.2; 3L5; CE00570; Q7JMS5_CAEEL; WBGene00009595; WP:CE00570
F40F4.7 F40F4.7 P W All gene names: F40F4.7; CE28316; WBGene00018238; WP:CE28316; XD864
F40F8.1 F40F8.1 P W All gene names: F40F8.1; F40F8.1.1; F40F8.1.2; 2L419; CE05842; WBGene00009575; WP:CE05842 WormBase description: UMP-CMP kinase like
F40F8.10 F40F8.10 P W All gene names: rps-9; F40F8.10; F40F8.10.1; F40F8.10.2; F40F8.10.3; 2L416; CE05849; NM_063983; RS9_CAEEL; WBGene00004478; WP:CE05849 WormBase description: rps-9 encodes a small ribosomal subunit S9 protein. WormBase CDS description: ribosomal protein S9
F40G9.10 F40G9.10 P W All gene names: F40G9.10; 3A790; CE19857; WBGene00018246; WP:CE19857
F40H6.5 F40H6.5 P W All gene names: F40H6.5; 3H136; CE39934; WBGene00018255; WP:CE39934; YPX5_CAEEL
F41C3.2 F41C3.2 P W All gene names: F41C3.2; 2F41; CE39500; WBGene00018268; WP:CE39500 WormBase description: Sodium/phosphate transporter protein
F41E7.9 F41E7.9 P W All gene names: F41E7.9; CE34858; WBGene00009625; WP:CE34858; XK930
F41G4.1 F41G4.1 P W All gene names: F41G4.1; CE04545; Q95YA5_CAEEL; WBGene00018307; WP:CE04545; XR457
F41H10.5 F41H10.5 P W All gene names: F41H10.5; 4G123; CE10280; WBGene00018318; WP:CE10280
F41H10.8 F41H10.8 P W All gene names: elo-6; F41H10.8; 4G152; CE10286; NM_068396; WBGene00001244; WP:CE10286 WormBase description: The elo-6 gene encodes a paralog of elo-1 and elo-2, each of which encodes a polyunsaturated fatty acid (PUFA) elongase; ELO-6 may be required for a normally high growth rate.
F42A9.2 F42A9.2 P W All gene names: lin-49; F42A9.2; 4J389; CE07224; LIN49_CAEEL; NM_069074; WBGene00003034; WP:CE07224 WormBase description: zinc-finger protein
F42A9.4 F42A9.4 P W All gene names: cyp-33E3; F42A9.4; 4J375; CE07226; NM_069070; WBGene00018333; WP:CE07226
F42D1.3 F42D1.3 P W All gene names: F42D1.3; F42D1.3.1; F42D1.3.2; CE31511; WBGene00009629; WP:CE31511; XP421 WormBase description: G-protein coupled receptor
F42F12.3 F42F12.3 P W All gene names: F42F12.3; CE03314; Q20344_CAEEL; WBGene00009635; WP:CE03314; XM969 WormBase description: 3-oxo-5-alpha-steroid 4-dehydrogenase
F42G8.11 F42G8.11 P W All gene names: sph-1; F42G8.11; 4I896; CE17070; NM_068959; WBGene00004979; WP:CE17070 WormBase description: sph-1 encodes a member of the synaptophysin/synaptoporin family that contains a MARVEL domain, a membrane-associating domain found in lipid-associating proteins, and contains a transmembrane domain. WormBase CDS description: synaptic vesicle channel protein
F42G8.12 F42G8.12 P W All gene names: isp-1; F42G8.12; F42G8.12.1; F42G8.12.2; 4I900; CE17071; NM_068960; WBGene00002162; WP:CE17071 WormBase description: isp-1 encodes a Rieske iron sulphur protein (ISP) which is a subunit of the mitochondrial complex III in the mitochondrial membrane; the subunits are highly conserved in all mitochondria and aerobic bacteria; mitochondrial complex III catalyses electron transport from ubiquinol to cytochrome c; isp-1 mutants show low oxygen consumption, a decreased sensitivity to reactive oxygen species and increased lifespan suggesting that mitochondrial electron transport is a key factor affecting life span; isp-1 affects the rates of physiological processes like reproduction and development and also affects behavior. WormBase CDS description: ubiquinol-cytochrome C reductase
F43C1.3 F43C1.3 P W All gene names: F43C1.3; 3F334; CE37012; WBGene00009648; WP:CE37012
F43C11.7 F43C11.7 P W All gene names: F43C11.7; 2C627; CE23722; Q9U5C1_CAEEL; WBGene00018384; WP:CE23722
F43D2.1 F43D2.1 P W All gene names: F43D2.1; 5P93; CE38186; WBGene00009650; WP:CE38186 WormBase description: G1/S-specfic cyclin C like
F43E2.4 F43E2.4 P W All gene names: haf-2; F43E2.4; 2H644; CE07240; NM_063136; WBGene00001812; WP:CE07240 WormBase description: haf-2 encodes a predicted transmembrane protein of the ATP-binding cassette (ABC) transporter superfamily; by homology, HAF-2 is proposed to function in ATP-dependent transport of molecules across plasma and intracellular membranes; however, as loss of HAF-2 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of HAF-2 in C. elegans development and/or behavior is not yet known. WormBase CDS description: membrane transport protein
F43H9.3 F43H9.3 P W All gene names: F43H9.3; 5I504; CE07247; WBGene00018399; WP:CE07247
F44C4.2 F44C4.2 P W All gene names: nhr-37; F44C4.2; 5H103; CE07250; WBGene00018412; WP:CE07250 WormBase description: zinc finger-containing protein
F44E2.10 F44E2.10 P W All gene names: F44E2.10; 3J920; CE26893; WBGene00018423; WP:CE26893
F44E2.3 F44E2.3 P W All gene names: F44E2.3; 3J918; CE00181; WBGene00018417; WP:CE00181; YL53_CAEEL WormBase description: DnaJ
F44G3.6 F44G3.6 P W All gene names: skr-3; F44G3.6; F44G3.6.1; F44G3.6.2; 5Q603; CE16037; NM_074658; WBGene00004809; WP:CE16037 WormBase description: The skr-3 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-3(RNAi) animals are at least superficially normal.
F45C12.3 F45C12.3 P W All gene names: F45C12.3; 2C19; CE10440; WBGene00018434; WP:CE10440
F45E1.7 F45E1.7 P W All gene names: F45E1.7; F45E1.7a.1; F45E1.7a.2; CE29323; CE37111; Q09989_CAEEL; WBGene00018467; WP:CE29323; WP:CE37111; XI608
F45G2.6 F45G2.6 P W All gene names: trf-1; F45G2.6; 3O521; CE37519; NM_067372; WBGene00006612; WP:CE37519 WormBase description: The trf-1 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis. WormBase CDS description: Zinc finger, C3HC4 type (RING finger)
F45H7.6 F45H7.6 P W All gene names: F45H7.6; 3E468; CE01588; WBGene00009738; WP:CE01588 WormBase description: Yeast ORF YKL162
F46B3.17 F46B3.17 P W All gene names: col-163; F46B3.17; 5V71; CE33787; WBGene00000736; WP:CE33787 WormBase description: collagen
F46B3.5 F46B3.5 P W All gene names: grd-2; F46B3.5; 5V83; CE34022; NM_075576; WBGene00001691; WP:CE34022 WormBase description: grd-2 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, four Ground domains, an short region of low-complexity sequence, and a Hint/Hog domain; the Hint/Hog domain is predicted to cut GRD-2 into two halves and then covalently link cholesterol to the C-terminus of the Ground domain; the four N-terminal Ground domains are predicted to form one or more cysteine-crosslinked proteins involved in intercellular signalling; Ground domains have subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-2 is weakly required for normal molting; GRD-2 is also required for normal adult alae formation, growth to full size, locomotion, and male tail development; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
F46C5.8 F46C5.8 P W All gene names: F46C5.8; 2J103; CE03349; WBGene00009783; WP:CE03349; YAF8_CAEEL WormBase description: endoplasmic reticular protein
F46C5.9 F46C5.9 P W All gene names: F46C5.9; 2J100; CE10584; P90814_CAEEL; WBGene00009784; WP:CE10584 WormBase description: G-protein
F46G10.3 F46G10.3 P W All gene names: sir-2.3; F46G10.3; CE02239; NM_077819; WBGene00004802; WP:CE02239; XN951 WormBase description: SIR
F47D12.7 F47D12.7 P W All gene names: F47D12.7; 3H384; CE01951; WBGene00018563; WP:CE01951; YR47_CAEEL
F47G6.2 F47G6.2 P W All gene names: F47G6.2; 1B951; CE28399; WBGene00018579; WP:CE28399
F47G6.4 F47G6.4 P W All gene names: hum-3; spe-15; F47G6.4; 1B937; CE17841; NM_058455; WBGene00004969; WP:CE17841 WormBase description: spe-15 encodes an unconventional myosin, and is homologous to both Drosophila and mouse myosin VI; spe-15 was identified in screens for mutants that have defective spermatogenesis; spe-15 is required during the terminal stages of spermatogenesis for the asymmetric partitioning of organelles like the mitochondria and for the proper partitioning of specialized structures called the fibrous-body membranous organelles into the spermatid; mutant spe-15 spermatids contain actin filaments in contrast to wild-type which lack them; spe-15 is also required for the proper morphology and activation of the spermatid; the human gene MYOSIN VI (MYO6; OMIM:600970), when mutated leads to disease that affects hearing.
F47H4.10 F47H4.10 P W All gene names: skr-5; F47H4.10; 5R829; CE20827; NM_074992; WBGene00004811; WP:CE20827 WormBase description: The skr-5 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-5(RNAi) animals are at least superficially normal.
F48C11.1 F48C11.1 P W All gene names: gpa-6; F48C11.1; CE20829; GPA6_CAEEL; NM_077788; WBGene00001668; WP:CE20829; XN811 WormBase description: gpa-6 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases that affects response to water-soluble odorants; it is expressed in AWA amphid neurons, the PHB sensory cell, and (at low levels) in ASI amphid neurons. WormBase CDS description: guanine nucleotide-binding protein
F48E3.2 F48E3.2 P W All gene names: F48E3.2; CE02750; WBGene00018603; WP:CE02750; XI108 WormBase description: Glucose transporter
F48E3.7 F48E3.7 P W All gene names: acr-22; F48E3.7; CE28403; NM_076869; WBGene00000061; WP:CE28403; XI124 WormBase description: acr-22 encodes a predicted member of the nicotinic acetylcholine receptor nonalpha subunit family with highest similarity to human neuronal acetylcholine receptor alpha-9 subunit. WormBase CDS description: Acetycholine receptor
F48E8.4 F48E8.4 P W All gene names: F48E8.4; 3G547; CE37377; WBGene00018611; WP:CE37377
F48G7.11 F48G7.11 P W All gene names: nhr-190; F48G7.11; 5B120; CE35318; WBGene00018622; WP:CE35318 WormBase description: nuclear hormone receptor
F49A5.5 F49A5.5 P W All gene names: clec-28; F49A5.5; 5R343; CE35549; CE38363; O45532_CAEEL; WBGene00009857; WP:CE35549; WP:CE38363 WormBase description: Lectin C-type domain short and long forms (2 domains)
F49E11.10 F49E11.10 P W All gene names: F49E11.10; 4N823; CE05906; WBGene00009895; WP:CE05906 WormBase description: testis-specific protein TPX-1 like
F49E11.7 F49E11.7 P W All gene names: F49E11.7; 4N817; CE05903; WBGene00009893; WP:CE05903 WormBase description: serine/threonine protein phosphatase
F49E12.10 F49E12.10 P W All gene names: F49E12.10; 2I681; CE03386; WBGene00009903; WP:CE03386 WormBase description: ERG-3 like protein
F49E8.3 F49E8.3 P W All gene names: pam-1; F49E8.3; F49E8.3a.1; F49E8.3a.2; F49E8.3a.3; 4I310; CE10790; CE37649; NM_068819; WBGene00003914; WP:CE10790; WP:CE37649
F49E8.4 F49E8.4 P W All gene names: cdd-2; F49E8.4; 4I312; CE10792; NM_068820; Q20628_CAEEL; WBGene00000392; WP:CE10792 WormBase description: A functional cytidine deaminase that affects morphology of embryos; it is expressed at all life cycle stages. WormBase CDS description: cytidine deaminase
F49H6.5 F49H6.5 P W All gene names: F49H6.5; 5R501; CE18715; WBGene00009908; WP:CE18715 WormBase description: The F49H6.5 gene encodes a homolog of the human gene MOCS1A, which when mutated leads to molybdenum cofactor deficiency (OMIM:252150).
F52B10.1 F52B10.1 P W All gene names: nmy-1; F52B10.1; CE31177; NM_076103; Q20641_CAEEL; WBGene00003776; WP:CE31177; XD535 WormBase description: nmy-1 encodes a class II non-muscle myosin heavy chain related to Drosophila zipper, which plays a role in several aspects of embryonic morphogenesis; in C. elegans, NMY-1 is required for embryonic elongation and establishment of normal body morphology; however, nmy-1 functions redundantly with another non-muscle myosin heavy chain gene, nmy-2, during elongation and establishment of normal body morphology; mutations in nmy-1 suppress the hypercontraction phenotype produced by mutations in mel-11, a myosin phosphatase that regulates actomyosin filament contraction; in addition, NMY-1 may partner with MLC-4, myosin light chain 4, during elongation; NMY-1 expression is detected during embryogenesis, particularly at the onset of elongation. WormBase CDS description: myosin
F52B5.1 F52B5.1 P W All gene names: abts-1; F52B5.1; 1I874; CE27167; NM_059857; WBGene00009920; WP:CE27167 WormBase description: anion exchange protein
F52B5.2 F52B5.2 P W All gene names: F52B5.2; 1I892; CE24993; WBGene00009921; WP:CE24993 WormBase description: serine/threonine kinase (2 domains)
F52C6.11 F52C6.11 P W All gene names: bath-2; F52C6.11; 2C178; CE35974; WBGene00018668; WP:CE35974
F52C6.3 F52C6.3 P W All gene names: phi-32; F52C6.3; 2C181; CE36857; O44820_CAEEL; WBGene00018660; WP:CE36857
F52C9.7 F52C9.7 P W All gene names: F52C9.7; 3G399; CE04619; WBGene00018677; WP:CE04619
F52D10.1 F52D10.1 P W All gene names: abts-2; F52D10.1; CE39940; NM_077535; WBGene00009929; WP:CE39940; XM209 WormBase description: The F52D10.1 gene encodes a protein that is homologous to the Arabidopsis and Saccharomyces boron exporters, BOR1 and YNL275w, and similar to the to the human BOR1/YNL275w ortholog, BTS1; like BOR1 and YNL275w, F52D10.1 protein might act to export borate ions. WormBase CDS description: anion exchange protein
F52E10.5 F52E10.5 P W All gene names: ifa-3; F52E10.5; CE34875; Cel IF A3; CelIF a3; IFA3_CAEEL; NM_078248; WBGene00002051; WP:CE34875; XQ882 WormBase description: ifa-3 encodes an essential intermediate filament protein that is coexpressed with the essential IF protein IFB-1; IFA-3 is required for survival past early larval stages, correct positioning of excretory canals and body muscles, attachment of cuticle to hypodermis, and locomotion; IFA-3 forms heteropolymeric intermediate filaments in vitro with an equimolar mixture of IFB-1; IFA-3 is expressed in embryonic and larval, but not adult, hypodermis. WormBase CDS description: intermediate filament protein
F52F12.4 F52F12.4 P W All gene names: lsl-1; F52F12.4; 1K479; CE36164; NM_060220; WBGene00009937; WP:CE36164 WormBase description: Zinc finger, C2H2 type (4 domains)
F52F12.6 F52F12.6 P W All gene names: ekl-2; F52F12.6; 1K482; CE24995; WBGene00009939; WP:CE24995 WormBase description: C2HC type zinc finger protein
F52H3.3 F52H3.3 P W All gene names: bath-38; F52H3.3; 2K334; BAT38_CAEEL; CE03399; WBGene00009945; WP:CE03399 WormBase description: BTB (also known as BR-C/Ttk) domain.
F53A2.4 F53A2.4 P W All gene names: nud-1; F53A2.4; 3O429; CE16096; NM_067348; WBGene00003829; WP:CE16096 WormBase description: nud-1 encodes the C. elegans ortholog of the Aspergillus nidulans nudC, which mediates nuclear migration along Aspergillus hyphae.
F53A3.2 F53A3.2 P W All gene names: polh-1; F53A3.2; 3D36; CE28442; NM_065079; WBGene00018721; WP:CE28442 WormBase description: The F53A3.2 gene encodes an ortholog of the human gene XERODERMA PIGMENTOSUM VARIANT RAD30 (POLH; OMIM:603968), which when mutated leads to xeroderma pigmentosum (OMIM:278750).
F53A3.7 F53A3.7 P W All gene names: F53A3.7; 3D41; CE23764; WBGene00018723; WP:CE23764
F53C11.7 F53C11.7 P W All gene names: swan-2; tag-206; F53C11.7; F53C11.7.1; F53C11.7.2; F53C11.7.3; 5O282; CE24997; WBGene00009976; WP:CE24997 WormBase description: Yeast hypothetical protein YPL247C like
F53C3.1 F53C3.1 P W All gene names: F53C3.1; 2E203; CE35938; WBGene00018745; WP:CE35938 WormBase description: protein kinase
F53C3.12 F53C3.12 P W All gene names: F53C3.12; 2E200; CE32672; WBGene00018755; WP:CE32672
F53C3.9 F53C3.9 P W All gene names: F53C3.9; 2E173; WBGene00018753
F53E2.1 F53E2.1 P W All gene names: tag-304; F53E2.1; F53E2.A; 5B949; CE30280; WBGene00018757; WP:CE30280
F53F1.2 F53F1.2 P W All gene names: F53F1.2; 5N887; CE10934; WBGene00009980; WP:CE10934 WormBase description: aldehyde reductase
F53F10.3 F53F10.3 P W All gene names: F53F10.3; F53F10.3.1; F53F10.3.2; 1E395; CE28447; WBGene00018765; WP:CE28447; YXX3_CAEEL
F53F4.3 F53F4.3 P W All gene names: F53F4.3; 5O73; CE10958; TBCB_CAEEL; WBGene00009987; WP:CE10958 WormBase description: S.pombe hypothetical protein SPAC4G9.01 like
F53F4.5 F53F4.5 P W All gene names: fmo-14; fmo-4; F53F4.5; F53F4.5.1; F53F4.5.2; 5O84; CE30676; NM_073969; WBGene00001479; WP:CE30676 WormBase description: fmo-14 encodes a protein with homology to human hepatic flavin-containing monooxygenase 5. WormBase CDS description: flavin-containing monoxygenase
F53G2.6 F53G2.6 P W All gene names: tsr-1; F53G2.6; 2C752; CE37021; NM_061878; O17244_CAEEL; WBGene00006647; WP:CE37021 WormBase description: tsr-1 encodes a homolog of human transportin-SR, a nuclear transport receptor, and affects embryonic viability.
F53H4.6 F53H4.6 P W All gene names: F53H4.6; CE33794; WBGene00010011; WP:CE33794; XQ472
F53H8.1 F53H8.1 P W All gene names: apm-3; apt-7; F53H8.1; CE35723; NM_075783; WBGene00000164; WP:CE35723; XB573 WormBase description: apt-7 gene encodes an adaptin, orthologous to the mu3 subunit of adaptor protein complex 3 (AP-3); APT-7 is also orthologous to human HPS, which when mutated leads to Hermansky-Pudlak syndrome (OMIM:203300); based on structural similarity, APT-7 may be involved in the formation of intracellular transport vesicles. WormBase CDS description: clathrin coat assembly protein
F54B3.1 F54B3.1 P W All gene names: F54B3.1; 2K557; CE17865; WBGene00010013; WP:CE17865 WormBase description: ATP binding protein (CDC48/PAS1/SEC18 family)
F54C1.2 F54C1.2 P W All gene names: dom-3; F54C1.2; F54C1.2.1; F54C1.2.2; 1F573; CE11044; DOM3Z_CAEEL; NM_059095; WBGene00001050; WP:CE11044
F54C8.1 F54C8.1 P W All gene names: F54C8.1; 3K531; CE00187; HCDH1_CAEEL; WBGene00010035; WP:CE00187 WormBase description: 3-hydroxyacyl-CoA dehydrogenase
F54C9.2 F54C9.2 P W All gene names: stc-1; F54C9.2; 2I854; CE32895; NM_063407; STCH; WBGene00006059; WP:CE32895 WormBase description: Heat shock 70Kd protein (HSP70)
F54C9.9 F54C9.9 P W All gene names: F54C9.9; 2I871; CE20865; WBGene00010044; WP:CE20865
F54D12.3 F54D12.3 P W All gene names: aat-7; F54D12.3; 2B679; CE35941; NM_061559; WBGene00000008; WP:CE35941 WormBase description: aat-7 encodes a predicted amino acid transporter catalytic subunit; unlike catalytic subunits in other organisms, however, AAT-7 does not contain the highly conserved cysteine residue known to facilitate covalent interaction with a glycoprotein subunit, suggesting that AAT-7 does not require this residue for heterodimer formation or alternatively, does not require the glycoprotein subunit for function.
F54E12.1 F54E12.1 P W All gene names: his-55; F54E12.1; 4M102; NM_069737; WBGene00001929 WormBase description: his-55 encodes an H3 histone; by homology, HIS-55 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-55 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV. WormBase CDS description: histone H3
F54E7.7 F54E7.7 P W All gene names: rcn-1; F54E7.7; 3G772; CCPL_CAEEL; CE31002; DSCR1L; NM_065822; SC; WBGene00004321; WP:CE31002 WormBase description: rcn-1 encodes a calcipressin, which binds and inhibits calcineurin; RCN-1's orthologs include yeast Rcn1p and human DSCR1 (OMIM:602917; overexpressed in Down syndrome and Alzheimer disease); rcn-1 is expressed in hypodermal seam cells, various neurons, vulval epithelial and muscle cells, marginal pharyngeal cells, and in the male tail; rcn-1 transcription is regulated by TAX-6, and RCN-1 binds TAX-6 protein if free Ca[2+] is present; RCN-1 overexpression, like calcineurin deficiency, causes defects in body size, cuticle thickness, fertility, growth rate, and serotonin-resistance in egg-laying.
F54F11.2 F54F11.2 P W All gene names: F54F11.2; 2N805; CE11095; WBGene00010070; WP:CE11095 WormBase description: F54F11.2 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F54F11.2 has no clear orthologs in other organisms. WormBase CDS description: Zinc-binding metalloprotease
F54F12.1 F54F12.1 P W All gene names: F54F12.1; 3O140; CE16114; WBGene00010072; WP:CE16114 WormBase description: tyrosine protein phosphatase
F54F3.3 F54F3.3 P W All gene names: F54F3.3; 5N401; CE18732; WBGene00010062; WP:CE18732 WormBase description: lipase
F54F7.7 F54F7.7 P W All gene names: F54F7.7; CE35555; WBGene00010067; WP:CE35555; XM484
F54G8.4 F54G8.4 P W All gene names: nhl-1; F54G8.4; 3K238; CE05942; NHL1_CAEEL; NM_066627; WBGene00003597; WP:CE05942 WormBase description: The nhl-1 gene encodes an RBCC protein, orthologous to the mammalian protein BERP; its C. elegans paralogs include ncl-1 and lin-41. WormBase CDS description: Zinc finger, C3HC4 type (RING finger)
F54G8.5 F54G8.5 P W All gene names: ptr-9; F54G8.5; 3K246; CE37974; NM_066629; PTR; PTR9_CAEEL; WBGene00004223; WP:CE37974 WormBase description: ptr-9 encodes an ortholog of Drosophila and human PTCHD3, which defines one of seven paralogous families of sterol sensing domain (SSD) proteins; PTR-9 is required for normal development in mass RNAi assays.
F54H5.2 F54H5.2 P W All gene names: F54H5.2; 2G919; CE01965; WBGene00018839; WP:CE01965
F55A4.4 F55A4.4 P W All gene names: F55A4.4; CE11105; WBGene00018856; WP:CE11105; XB644
F55D10.2 F55D10.2 P W All gene names: rpl-25.1; F55D10.2; F55D10.2.1; F55D10.2.2; CE02777; NM_076407; R23A1_CAEEL; WBGene00004438; WP:CE02777; XF335 WormBase description: rpl-25.1 encodes a large ribosomal subunit L23a protein. WormBase CDS description: Ribosomal protein L23
F55D12.4 F55D12.4 P W All gene names: unc-55; F55D12.4; 1I472; CE05957; NM_059780; WBGene00006790; WP:CE05957 WormBase description: nuclear hormone receptor
F55E10.7 F55E10.7 P W All gene names: F55E10.7; CE02787; WBGene00018886; WP:CE02787; XI968
F55F1.3 F55F1.3 P W All gene names: F55F1.3; CE30148; WBGene00018889; WP:CE30148
F55F8.4 F55F8.4 P W All gene names: tag-326; F55F8.4; F55F8.4.1; F55F8.4.2; F55F8.4.3; 1G222; CE11194; WBGene00018892; WP:CE11194
F55G1.10 F55G1.10 P W All gene names: his-61; F55G1.10; 4I250; NM_068800; WBGene00001935 WormBase description: his-61 encodes an H2A histone. WormBase CDS description: Histone
F55G1.2 F55G1.2 P W All gene names: his-59; F55G1.2; 4I253; NM_068803; WBGene00001933 WormBase description: his-59 encodes an H3 histone; by homology, HIS-59 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-59 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV. WormBase CDS description: Histone
F56A11.3 F56A11.3 P W All gene names: efn-4; mab-26; F56A11.3; 4B319; CE29503; EFN4_CAEEL; NM_067546; WBGene00001165; WP:CE29503 WormBase description: efn-4 encodes a member of the ephrin family of ligands that affects neuroblast migrations during closure of the ventral gastrulation cleft and subsequent epidermal morphogenesis, possibly functioning independently of EFN-1, EFN-2, EFN-3, and the VAB-1 receptor during morphogenesis; can interact with VAB-1 in vitro, and is expressed in neural and epidermal precursors at the 100-cell stage, in head neurons, pharyngeal cells, lateral and tail neurons, and in the ectoderm during epidermal enclosure.
F56A11.6 F56A11.6 P W All gene names: F56A11.6; 4B334; CE36868; WBGene00018926; WP:CE36868
F56A3.2 F56A3.2 P W All gene names: F56A3.2; 1F753; CE11216; WBGene00018909; WP:CE11216
F56A3.4 F56A3.4 P W All gene names: spd-5; F56A3.4; 1F740; CE28834; NM_059138; SPD5_CAEEL; WBGene00004955; WP:CE28834
F56C11.3 F56C11.3 P W All gene names: F56C11.3; 1A656; CE17903; WBGene00018955; WP:CE17903
F56D2.2 F56D2.2 P W All gene names: F56D2.2; 3G677; CE11228; WBGene00018964; WP:CE11228
F56F4.3 F56F4.3 P W All gene names: F56F4.3; 1G721; CE39021; WBGene00018980; WP:CE39021
F56H11.4 F56H11.4 P W All gene names: elo-1; pea-1; F56H11.4; 4K291; CE05979; CEEL01; NM_069288; WBGene00001239; WP:CE05979; ceelo1 WormBase description: elo-1 encodes a component of C-18 polyunsaturated fatty acid (PUFA) elongase that is required for normal elongation of n-6 and n-3 20-carbon PUFA in vivo; ELO-1 is a condensing enzyme that elongates n-6 and n-7 (and, with less efficiency, n-3) series C18 PUFAs. WormBase CDS description: Yeast YJT6 like
F56H6.8 F56H6.8 P W All gene names: clec-18; F56H6.8; 1M882; CE16136; WBGene00010169; WP:CE16136 WormBase description: CUB domain, Lectin C-type domain short and long forms (2 domains)
F56H9.3 F56H9.3 P W All gene names: gpa-8; F56H9.3; 5N120; CE05973; GPA8_CAEEL; NM_073759; WBGene00001670; WP:CE05973 WormBase description: gpa-8 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; expressed in URX, AQR, and PQR sensory cells. WormBase CDS description: guanine nucleotide-binding protein
F56H9.4 F56H9.4 P W All gene names: gpa-9; F56H9.4; 5N126; CE20886; GPA9_CAEEL; NM_073760; WBGene00001671; WP:CE20886 WormBase description: gpa-9 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ASJ, PHB, PVQ, pharyngeal muscle, and the spermatheca. WormBase CDS description: guanine nucleotide-binding protein
F57A10.5 F57A10.5 P W All gene names: nhr-60; F57A10.5; 5Q252; CE16151; NM_074529; WBGene00003650; WP:CE16151 WormBase description: Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains)
F57A8.2 F57A8.2 P W All gene names: F57A8.2; 5K530; CE31547; CE39508; WBGene00010178; WP:CE31547; WP:CE39508
F57B10.6 F57B10.6 P W All gene names: F57B10.6; 1H135; CE11308; WBGene00019004; WP:CE11308 WormBase description: F57B10.6 is orthologous to the human gene EXCISION REPAIR CROSS-COMPLEMENTING RODENT REPAIR DEFICIENCY, COMPLEMENTATION GROUP 5 (XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP G (COCKAYNE SYNDROME)) (ERCC5; OMIM:133530), which when mutated leads to disease. WormBase CDS description: DNA repair protein
F57B9.8 F57B9.8 P W All gene names: F57B9.8; 3I24; CE29411; WBGene00018999; WP:CE29411 WormBase description: putative protein tyrosine kinase
F58F6.1 F58F6.1 P W All gene names: col-104; F58F6.1; 4C118; CE17136; NM_067669; WBGene00000678; WP:CE17136 WormBase description: cuticular collagen
F58F6.2 F58F6.2 P W All gene names: col-105; F58F6.2; 4C122; CE17137; NM_067670; WBGene00000679; WP:CE17137 WormBase description: cuticular collagen
F58H12.1 F58H12.1 P W All gene names: kin-29; sma-11; sns-8; F58H12.1; CE28479; NM_076092; WBGene00002210; WP:CE28479; XD464 WormBase description: kin-29 encodes a serine/threonine kinase with significant homology in the kinase domain to the AMP-activated protein kinase (AMPK) and SNF1 kinases; the AMP-kinase cascade is activated by cellular stresses that deplete ATP; AMP-kinase is believed to protect the mammalian cell by 'switching off' ATP-consuming pathways like fatty acid synthesis, by phosphorylating key regulatory enzymes, and switching on alternative pathways for ATP generation; kin-29 is involved in regulating the expression of chemosensory receptors and entry into the daur pathway; kin-29 also affects body size via interaction with the Sma/Mab pathway and lifespan, with mutants exhibiting a smaller body size and increased life span; a functional KIN-29-GFP fusion protein is expressed in sensory neurons and many other cell types, and localizes to the cytoplasm; under conditions of cellular stress like heat shock and starvation, KIN-29-GFP translocates to the nucleus. WormBase CDS description: serine/threonine-protein kinase
F59A2.4 F59A2.4 P W All gene names: F59A2.4; 3E489; CE17941; CE39740; WBGene00010304; WP:CE17941; WP:CE39740; YMI4_CAEEL
F59A3.3 F59A3.3 P W All gene names: F59A3.3; 1G74; CE11420; RM24_CAEEL; WBGene00019076; WP:CE11420
F59A6.3 F59A6.3 P W All gene names: F59A6.3; 2F299; CE01981; WBGene00019085; WP:CE01981 WormBase description: Glycoprotein
F59B2.2 F59B2.2 P W All gene names: F59B2.2; 3K84; CE20899; WBGene00010307; WP:CE20899; YMJ2_CAEEL
F59C12.3 F59C12.3 P W All gene names: F59C12.3; CE39379; Q21036_CAEEL; WBGene00019102; WP:CE39379; XR218
F59C6.7 F59C6.7 P W All gene names: che-13; che-9; F59C6.7; 1L82; CE31704; NM_060348; WBGene00000492; WP:CE31704 WormBase description: che-13 encodes a novel protein homologous to mammalian IFT57/Hippi (OMIM:606621, protein interactor of Huntingtin-interacting protein 1 that is implicated in neuronal apoptosis in the Huntington disease state); CHE-13 is a proposed component of the intraflagellar transport (IFT) complex B, and is required for the construction and maintenance of cilia on a subset of sensory neurons; in addition, CHE-13 is required for proper localization of OSM-5, a murine polaris homolog, to IFT complex B; CHE-13 is expressed in ciliated sensory neurons including the amphids, phasmids, inner and outer labial neurons, and sensory rays of the male tail, localizing to the cilia base (transition zone) as well as to the axoneme; che-13 expression, like that of ciliogenic genes osm-1, osm-5, osm-6, and che-2, is positively regulated by the DAF-19 RFX-type transcription factor.
F59D12.1 F59D12.1 P W All gene names: F59D12.1; CE11490; WBGene00010329; WP:CE11490; XQ289 WormBase description: G-protein coupled receptor (gastrin/cholecystokinin)
F59D12.4 F59D12.4 P W All gene names: gpn-1; F59D12.4; CE26816; NM_078181; WBGene00001687; WP:CE26816; XQ301 WormBase description: gpn-1 encodes a glypican, a heparan sulfate proteoglycan anchored to the cell membrane by a GPI linkage, that is orthologous to Drosophila Dally-like (Dlp) and mammalian glypicans (OMIM:312870, mutated in Simpson-Golabi-Behmel overgrowth syndrome); by homology, GPN-1 is predicted to function as a cell surface protein that regulates intercellular signaling, perhaps within the context of cell division and growth regulation; however, as loss of gpn-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of GPN-1 in C. elegans development and/or behavior is not yet known. WormBase CDS description: glypican
F59D6.2 F59D6.2 P W All gene names: F59D6.2; 5D507; CE35328; WBGene00019104; WP:CE35328 WormBase description: aspartyl protease
F59E10.1 F59E10.1 P W All gene names: orc-2; F59E10.1; 2L167; CE11492; NM_063938; ORC2_CAEEL; WBGene00003882; WP:CE11492; ceOrc2 WormBase description: origin recognition complex, second largest subunit ORC2
F59E10.2 F59E10.2 P W All gene names: cyn-4; cyp-4; mog-6; F59E10.2; 2L162; CE01596; CYP4_CAEEL; NM_063936; WBGene00000880; WP:CE01596 WormBase description: cyp-4 encodes a peptidyl-propyl cis-trans isomerase of the cyclophilin family that is required for sexual differentiation of germ cells in hermaphrodites and affects body-wall muscle cell development; expression is most abundant in early larval stages and is observed exclusively in body- wall striated muscle cells. WormBase CDS description: cyclophilin
F59F4.4 F59F4.4 P W All gene names: acl-1; F59F4.4; CE11552; NM_078205; PLC1_CAEEL; WBGene00010339; WP:CE11552; XQ469 WormBase description: acl-1 encodes a 1-acyl-sn-glycerol-3-phosphate acyltransferase; ACL-1 is predicted to be a membrane protein that plays a role in phospholipid biosynthesis, but as loss of acl-1 activity via large-scale RNAi experiments results in no obvious defects, the precise role of ACL-1 in C. elegans development and/or behavior is not yet known. WormBase CDS description: 1-acyl-SN-glycerol-3-phosphate acyltransferase
F59F5.3 F59F5.3 P W All gene names: F59F5.3; CE31552; WBGene00010342; WP:CE31552; XL156 WormBase description: tyrosine-protein kinase
H01G02.2 H01G02.2 P W All gene names: H01G02.2; 4M562; CE35567; WBGene00010349; WP:CE35567 WormBase description: serine/threonine kinase (2 domains)
H06O01.1 H06O01.1 P W All gene names: pdi-3; H06O01.1; H06O01.1.1; H06O01.1.2; H06O01.1.3; 1H592; CE11570; CEERP57; NM_059594; WBGene00003964; WP:CE11570 WormBase description: pdi-3 encodes a protein disulfide isomerase (PDI) required for normal cuticle collagen deposition and, subliminally, for maintenance of normal body shape; PDI-3 has both PDI and calcium-dependent transglutaminase activity in vitro, crosslinking proteins through a gamma-glutamyl epsilon-lysine dual residue; PDI-3 is homologous to the human PDI ERp60, as well as a homolog in the dog heartworm Dirofilaria immitis that is required for larval molting; the joint PDI/transglutaminase activity of PDI-3 is biochemically conserved in nematodes and mammals; pdi-3 is constitutively and broadly expressed, particularly in gut and hypodermis. WormBase CDS description: protein disulphide isomerase ER-60 precursor like
H06O01.3 H06O01.3 P W All gene names: H06O01.3; 1H585; CE17969; WBGene00010370; WP:CE17969 WormBase description: retinal-binding protein like
H11E01.2 H11E01.2 P W All gene names: H11E01.2; CE30441; WBGene00019187; WP:CE30441; XC243 WormBase description: transporter
H11E01.3 H11E01.3 P W All gene names: H11E01.3; CE30442; WBGene00019188; WP:CE30442; XC237
H12D21.7 H12D21.7 P W All gene names: H12D21.7; 5P379; CE36178; WBGene00010383; WP:CE36178
H19N07.1 H19N07.1 P W All gene names: phi-19; H19N07.1; H19N07.1.1; H19N07.1.2; 5L592; CE32460; O45622_CAEEL; WBGene00010405; WP:CE32460 WormBase description: elongation factor
H22D14.1 H22D14.1 P W All gene names: nhr-267; H22D14.1; 4K48; CE19931; WBGene00010410; WP:CE19931 WormBase description: Zinc finger, C4 type (two domains)
H23N18.4 H23N18.4 P W All gene names: H23N18.4; H23N18.C; 5F379; CE20986; WBGene00019235; WP:CE20986 WormBase description: transferase
H28O16.2 H28O16.2 P W All gene names: H28O16.2; 1N240; CE34196; WBGene00010420; WP:CE34196
H34C03.2 H34C03.2 P W All gene names: H34C03.2; 4H525; CE19500; WBGene00019259; WP:CE19500 WormBase description: ubiquitin carboxy-terminal hydrolase
H35N03.1 H35N03.1 P W All gene names: exp-1; H35N03.1; 2G446; CE37026; NM_062828; WBGene00001373; WP:CE37026 WormBase description: ion channel
H38K22.3 H38K22.3 P W All gene names: tag-131; H38K22.3; 3F409; CE18831; WBGene00006478; WP:CE18831
H41C03.1 H41C03.1 P W All gene names: H41C03.1; 2G147; CE19507; WBGene00019268; WP:CE19507
H41C03.3 H41C03.3 P W All gene names: H41C03.3; H41C03.3.1; H41C03.3.2; 2G139; CE32055; WBGene00019270; WP:CE32055
H43I07.3 H43I07.3 P W All gene names: H43I07.3; 5E677; CE30081; WBGene00019276; WP:CE30081
JC8.5 JC8.5 P W All gene names: JC8.5; 4O11; CE38202; WBGene00010437; WP:CE38202
K01A11.4 K01A11.4 P W All gene names: spe-41; trp-3; K01A11.4; K01A11.4.1; K01A11.4.2; 3E530; CE03452; NM_065308; WBGene00004976; WP:CE03452; strpc3 WormBase description: spe-41 encodes one of three C. elegans calcium-permeable cation channels that are members of the TRPC (transient receptor potential canonical) subfamily of TRP channels; spe-41 activity is required in sperm for productive sperm-oocyte interactions during fertilization, after the point of gamete contact; SPE-41 is expressed solely in sperm and upon sperm activation, translocalizes from the membranous organelles of spermatids to the plasma membranes of the cell body and pseudopod of mature sperm, consistent with the observation that the activity of store-operated calcium channels in C. elegans is much higher in mature sperm than in spermatids; when expressed in mammalian tissue culture cells, SPE-41 activity is sufficient to enhance calcium influx. WormBase CDS description: calmodulin-binding trp1 like protein
K01D12.13 K01D12.13 P W All gene names: cdr-7; K01D12.13; 5M890; CE38388; CE38389; WBGene00010472; WP:CE38388; WP:CE38389 WormBase description: glutathione S-transferase
K01G5.1 K01G5.1 P W All gene names: tag-331; K01G5.1; 3K846; 3L846; CE26718; RN113_CAEEL; WBGene00010476; WP:CE26718 WormBase description: Zinc finger, C3HC4 type (RING finger)
K02C4.3 K02C4.3 P W All gene names: K02C4.3; 2I372; CE01599; UBPY_CAEEL; WBGene00010502; WP:CE01599 WormBase description: ubiquitin carboxyl-terminal hydrolase
K02E10.8 K02E10.8 P W All gene names: syg-1; K02E10.8; CE37121; NM_076056; WBGene00006365; WP:CE37121; XD128 WormBase description: syg-1 encodes a novel transmembrane protein that is a member of the immunoglobulin superfamily of proteins; during larval development, SYG-1 activity is required cell autonomously within the HSNL neuron to specify proper synaptic specificity with its targets, such as vulval muscles and the VC neuron; in regulating synapse formation, SYG-1 acts as a receptor for a second immunoglobulin superfamily protein, SYG-2, a synaptic guidepost protein that interacts with SYG-1 and whose activity is essential for proper SYG-1 localization in HSNL; expression of a SYG-1::GFP reporter fusion in HSNL under the control of the unc-86 promoter reveals that SYG-1 localizes to axons and accumulates at future sites of synaptic vesicle clustering, while expression under an endogenous reporter reveals weak expression in head motorneurons, occasionally in HSN neurons, and in other cells in the vulval region.
K02G10.8 K02G10.8 P W All gene names: dnj-14; K02G10.8; CE04708; NM_076405; WBGene00001032; WP:CE04708; XF330 WormBase description: This gene encodes a protein containing a DnaJ ('J') domain.
K02H11.6 K02H11.6 P W All gene names: K02H11.6; 5C6; CE30379; WBGene00019349; WP:CE30379 WormBase description: thioredoxin
K03E6.1 K03E6.1 P W All gene names: lim-6; K03E6.1; CE35737; NM_075803; WBGene00002988; WP:CE35737; XB697 WormBase description: lim-6 encodes a LIM class homeodomain protein that contains two Zinc-finger-like LIM domains N-terminal to a predicted DNA-binding homeodomain; LIM-6 is predicted to function as a transcription factor whose activity is required for regulating uterine morphogenesis and specific aspects of terminal neuronal differentiation, including normal axonal morphology, full expression of UNC-25/glutamic acid decarboxylase in select GABAergic neurons, and repression of sensory receptor gene expression in the ASEL chemosensory neuron; LIM-6 is expressed in a group of nine chemosensory-, inter-, and motorneurons, uterine toroid cells, spermathecal junction cells, and the binucleate excretory gland cell. WormBase CDS description: Homeobox protein
K03E6.4 K03E6.4 P W All gene names: K03E6.4; CE07330; Q21191_CAEEL; WBGene00019364; WP:CE07330; XB686
K03E6.7 K03E6.7 P W All gene names: K03E6.7; K03E6.7.1; K03E6.7.2; CE31197; WBGene00019365; WP:CE31197; XB704
K03H1.2 K03H1.2 P W All gene names: mog-1; K03H1.2; 3L42; CE01027; MOG1_CAEEL; NM_066811; WBGene00003389; WP:CE01027 WormBase description: The mog-1 gene encodes a DEAH helicase orthologous to the Drosophila CG1375/1405, the human PRP16, and the S. cerevisiae PRP16 proteins. WormBase CDS description: RNA helicase (DEAH subfamily)
K04A8.6 K04A8.6 P W All gene names: F46E10.A; K04A8.6; 5H14; CE27388; Q94251_CAEEL; WBGene00019377; WP:CE27388 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
K04C1.4 K04C1.4 P W All gene names: K04C1.4; CE35578; WBGene00010554; WP:CE35578; XO864 WormBase description: myosin light chain
K04C1.5 K04C1.5 P W All gene names: K04C1.5; CE06089; WBGene00010555; WP:CE06089; XO867 WormBase description: serine/threonine kinase
K04D7.1 K04D7.1 P W All gene names: K04D7.1; K04D7.1.1; K04D7.1.2; K04D7.1.3; K04D7.1.4; 4K941; CE06090; GBLP_CAEEL; WBGene00010556; WP:CE06090 WormBase description: guanine nucleotide-binding protein
K04F10.2 K04F10.2 P W All gene names: K04F10.2; 1G937; CE34333; WBGene00019395; WP:CE34333
K04F10.7 K04F10.7 P W All gene names: K04F10.7; 1G943; CE18015; O44772_CAEEL; WBGene00019399; WP:CE18015
K05C4.2 K05C4.2 P W All gene names: K05C4.2; K05C4.2.1; K05C4.2.2; 1P312; CE19970; WBGene00010579; WP:CE19970
K06A1.1 K06A1.1 P W All gene names: K06A1.1; 2G747; CE35990; WBGene00019424; WP:CE35990 WormBase description: transcription factor AP-2
K06A1.6 K06A1.6 P W All gene names: K06A1.6; 2G748; CE28048; DGKM_CAEEL; WBGene00019428; WP:CE28048 WormBase description: DIACYLGLYCEROL KINASE
K06A5.6 K06A5.6 P W All gene names: K06A5.6; K06A5.6.1; K06A5.6.2; 1H40; CE11776; WBGene00019433; WP:CE11776 WormBase description: acyl-coA dehydgrogenase
K06B4.7 K06B4.7 P W All gene names: nhr-197; K06B4.7; 5Q167; CE25931; NH197_CAEEL; WBGene00010602; WP:CE25931 WormBase description: Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains)
K06H7.3 K06H7.3 P W All gene names: K06H7.3; K06H7.3.1; K06H7.3.2; K06H7.3.3; 3J183; CE26941; NM_066364; WBGene00019457; WP:CE26941; YMX3_CAEEL WormBase description: Isopentenyl-diphosphate delta isomerase
K07A12.2 K07A12.2 P W All gene names: K07A12.2; 1J254; CE11866; WBGene00010621; WP:CE11866 WormBase description: Rat insulin-like growth factor binding protien complex acid labile chain like
K07A12.3 K07A12.3 P W All gene names: asg-1; K07A12.3; K07A12.3.1; K07A12.3.2; 1J269; ATPL1_CAEEL; CE11868; NM_059951; WBGene00000209; WP:CE11868 WormBase description: asg-1 encodes a homolog of the proton-translocating F0 ATP synthase complex subunit g; by homology, ASG-1 is predicted to function in ATP synthesis, although its precise role in ATP anabolism is not yet known; in C. elegans, asg-1 activity is required for transposon silencing in the germline, suggesting that healthy energy metabolism is necessary for this process; in addition, large-scale RNAi screens indicate that asg-1 activity is required for embryonic and germline development, normal post-embryonic growth rates, and normal body morphology. WormBase CDS description: ATP synthase subunit g
K07A12.4 K07A12.4 P W All gene names: K07A12.4; 1J264; CE39388; CE39389; WBGene00010622; WP:CE39388; WP:CE39389 WormBase description: elongation factor 1-alpha
K07C11.4 K07C11.4 P W All gene names: K07C11.4; 5I685; CE07347; Q21266_CAEEL; WBGene00019477; WP:CE07347 WormBase description: esterase
K07C5.6 K07C5.6 P W All gene names: K07C5.6; K07C5.6.1; K07C5.6.2; 5K834; CE06116; WBGene00010629; WP:CE06116 WormBase description: Zinc finger, CCHC class
K07E3.7 K07E3.7 P W All gene names: K07E3.7; K07E3.7a.1; K07E3.7a.2; K07E3.7a.3; CE37253; CE37254; WBGene00019493; WP:CE37253; WP:CE37254; XI710; YBF7_CAEEL
K07G5.1 K07G5.1 P W All gene names: K07G5.1; 1H730; ALP; CE06129; WBGene00010641; WP:CE06129 WormBase description: Leucine Rich Repeat (2 copies) (4 domains)
K07G5.3 K07G5.3 P W All gene names: K07G5.3; 1H741; CE06131; WBGene00010642; WP:CE06131 WormBase description: C2 domain
K07H8.1 K07H8.1 P W All gene names: K07H8.1; 4J61; CE18021; WBGene00019503; WP:CE18021
K08D12.1 K08D12.1 P W All gene names: pbs-1; K08D12.1; 4C474; CE25941; NM_067724; WBGene00003947; WP:CE25941 WormBase description: pbs-1 encodes a protease subunit with highest similarity to vertebrate proteasome subunit beta type 6 that affects fertility, embryonic viability, locomotion, and larval viability
K08D12.2 K08D12.2 P W All gene names: K08D12.2; 4C477; CE32468; WBGene00019536; WP:CE32468 WormBase description: K08D12.2 is orthologous to the human gene XRP2 PROTEIN (RP2; OMIM:312600), which when mutated leads to disease.
K08F4.2 K08F4.2 P W All gene names: K08F4.2; 4K892; CE37535; Q21351_CAEEL; WBGene00010677; WP:CE37535 WormBase description: RNA recognition motif. (aka RRM, RBD, or RNP domain)
K08F4.4 K08F4.4 P W All gene names: glt-3; K08F4.4; 4K897; CE06152; EAA3_CAEEL; NM_069443; WBGene00001621; WP:CE06152 WormBase description: glt-3 encodes an ortholog of glutamate/aspartate and neutral amino acid transporters. WormBase CDS description: excitatory amino acid transporter 2 like
K08F4.7 K08F4.7 P W All gene names: gst-4; K08F4.7; 4K907; CE06155; CeGST1; GST4_