Chi et al. 2006, ST Commonly down in mutants, 43 genes

Gene list file name:Chi2006_Gp2_CommonlyDown-in-mutants
Type of gene identifier:Cosmid name
Description:Chi et al 2006 Summplement Table, 43 genes commonly down-regulated in all three mutants.  
Organism:Caenorhabditis elegans (nematode)
Gene list type:Experimental

Gene name             Source Gene ID          Annotation                                                  Date       Added by    

B0035.8 B0035.8 P W All gene names: his-48; B0035.8; 4M89; CE05165; NM_069731; WBGene00001922; WP:CE05165 WormBase description: his-48 encodes an H2B histone; by homology, HIS-48 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-48 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV. WormBase CDS description: histone H2B
B0403.4 B0403.4 P W All gene names: tag-320; B0403.4; CE03880; PDIA6_CAEEL; WBGene00015168; WP:CE03880; XH686 WormBase description: protein disulfide-isomerase
C02E11.1 C02E11.1 P W All gene names: C02E11.1; C02E11.1a.1; C02E11.1a.2; 5B508; CE28528; CE32040; WBGene00015344; WP:CE28528; WP:CE32040
C03E10.5 C03E10.5 P W All gene names: C03E10.5; 5L757; CE15585; WBGene00007282; WP:CE15585
C07A12.4 C07A12.4 P W All gene names: pdi-2; C07A12.4; C07A12.4a.1; C07A12.4a.2; CE03972; CE31878; NM_076377; NM_182439; PDI2_CAEEL; WBGene00003963; WP:CE03972; WP:CE31878; XF145 WormBase description: protein disulfide isomerase
C09B8.4 C09B8.4 P W All gene names: C09B8.4; CE30242; WBGene00015623; WP:CE30242; XG638
C15H9.6 C15H9.6 P W All gene names: hsp-3; C15H9.6; C15H9.6.1; C15H9.6.2; C15H9.6.3; CE08177; HSP7C_CAEEL; NM_076618; WBGene00002007; WP:CE08177; XG708 WormBase description: hsp-3 encodes a heat shock response 70 (hsp70) protein orthologous to human glucose regulated protein 78 (grp78/BiP, OMIM:138120); HSP-3 likely functions as a molecular chaperone, and is expressed constitutively (expression is not heat inducible) throughout development with greatest abundance during the L1 larval stage; HSP-3 contains a long hydrophobic amino terminus and a carboxyl terminal KDEL sequence suggesting that it may be retained in the endoplasmic reticulum. WormBase CDS description: heat shock protein
C17E7.4 C17E7.4 P W All gene names: C17E7.4; 5E371; CE08264; O16393_CAEEL; WBGene00015899; WP:CE08264
C27C12.4 C27C12.4 P W All gene names: C27C12.4; CE33976; WBGene00007774; WP:CE33976; XP473
C39D10.7 C39D10.7 P W All gene names: C39D10.7; CE29712; Q18529_CAEEL; WBGene00016534; WP:CE29712; XI528 WormBase description: similar to C. elegans proteins B0280.5, R02F2.4 and C07G2.1
F08F3.6 F08F3.6 P W All gene names: F08F3.6; 5F896; CE09261; WBGene00017263; WP:CE09261 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
F11G11.2 F11G11.2 P W All gene names: gst-7; F11G11.2; 2F173; CE07055; GST7_CAEEL; NM_062482; WBGene00001755; WP:CE07055 WormBase description: gst-7 encodes a predicted glutathione S-transferase. WormBase CDS description: glutathione S-transferase
F14D7.2 F14D7.2 P W All gene names: F14D7.2; 5O772; CE09380; WBGene00008789; WP:CE09380
F17E9.12 F17E9.12 P W All gene names: his-31; F17E9.12; 4J96; NM_069005; WBGene00001905 WormBase description: his-31 encodes an H4 histone; his-31 is contained within the histone gene cluster HIS5.
F20H11.5 F20H11.5 P W All gene names: F20H11.5; 3H675; CE09514; OXDA2_CAEEL; WBGene00017648; WP:CE09514 WormBase description: D-amino acid oxidase
F25H5.4 F25H5.4 P W All gene names: eft-2; F25H5.4; F25H5.4.1; F25H5.4.2; F25H5.4.3; F25H5.4.4; F25H5.4.5; 1J741; CE15900; EF2_CAEEL; NM_060056; WBGene00001167; WP:CE15900 WormBase description: eft-2 encodes a homolog of translation elongation factor 2 (EF-2), a GTP-binding protein essential for the elongation phase of protein synthesis; eft-2 is required for embryogenesis and vulval morphogenesis, and is expressed during all stages of development, including the dauer larval stage. WormBase CDS description: Elongation factor Tu family (contains ATP/GTP binding P-loop)
F27B3.2 F27B3.2 P W All gene names: acr-21; F27B3.2; 3H673; CE39358; NM_066051; WBGene00000060; WP:CE39358 WormBase description: acr-21 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR); ACR-21 is a highly divergent member of the 'ACR-16' class of nAChR subunits, which includes ACR-7, ACR-9, ACR-10, ACR-11, ACR-14, ACR-15, ACR-16, and ACR-19, and is most closely related to the alpha-7 subunits of vertebrate nAChRs. WormBase CDS description: channel protein
F35H10.1 F35H10.1 P W All gene names: his-30; F35H10.1; 4J93; NM_069003; WBGene00001904 WormBase description: his-30 encodes an H2A histone; by homology, HIS-30 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-30 is a replication-dependent histone locus that resides in the HIS5 cluster on chromosome IV. WormBase CDS description: histone H2A
F41C3.5 F41C3.5 P W All gene names: F41C3.5; F41C3.5.1; F41C3.5.2; 2F29; CE02733; WBGene00018271; WP:CE02733; YUW5_CAEEL WormBase description: Serine carboxypeptidase
F45F2.2 F45F2.2 P W All gene names: his-39; F45F2.2; 5J17; CE36851; NM_072800; WBGene00001913; WP:CE36851 WormBase description: his-39 encodes an H2B histone; by homology, HIS-39 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; loss of his-39 function via RNA-mediated interference (RNAi) does not result in any abnormalities; his-39 is a replication-dependent histone locus that resides in the HIS2 cluster on chromosome V. WormBase CDS description: histone H4
F45F2.4 F45F2.4 P W All gene names: his-7; F45F2.4; 5J13; NM_072797; WBGene00001881 WormBase description: his-7 encodes an H2A histone. WormBase CDS description: histone H2A
F48E3.3 F48E3.3 P W All gene names: F48E3.3; CE02751; WBGene00018604; WP:CE02751; XI114 WormBase description: killer toxin-resistance protein (S. cerevisiae)
F48E3.4 F48E3.4 P W All gene names: F48E3.4; CE35547; WBGene00018605; WP:CE35547; XI112
F54C9.8 F54C9.8 P W All gene names: puf-5; F54C9.8; 2I867; CE02258; NM_063413; WBGene00004241; WP:CE02258 WormBase description: Pumilio-family RNA binding domains (aka PUM-HD, Pumilio homology domain) (6 domains)
F54F7.2 F54F7.2 P W All gene names: F54F7.2; CE37524; WBGene00010064; WP:CE37524; XM461
F55G1.11 F55G1.11 P W All gene names: his-60; F55G1.11; 4I252; CE07287; NM_068802; WBGene00001934; WP:CE07287 WormBase description: his-60 encodes an H4 histone; by homology, HIS-60 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-60 expression is detected in early embryos, beginning at the 28-cell stage and continuing through the comma stage (early morphogenesis); his-60 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV. WormBase CDS description: Histone
H02I12.6 H02I12.6 P W All gene names: his-66; H02I12.6; 4M164; H2B4_CAEEL; NM_069748; WBGene00001940 WormBase description: his-66 encodes an H2B histone. WormBase CDS description: Core histones H2A, H2B, H3 and H4
H13N06.6 H13N06.6 P W All gene names: tbh-1; H13N06.6; CE31553; NM_078161; WBGene00006541; WP:CE31553; XQ120 WormBase description: tbh-1 is orthologous to the human gene DOPAMINE BETA-HYDROXYLASE (DOPAMINE BETA-MONOOXYGENASE) (DBH; OMIM:223360), which when mutated leads to disease. WormBase CDS description: Copper type II, ascorbate-dependent monooxygenase
K08H10.1 K08H10.1 P W All gene names: lea-1; K08H10.1; K08H10.1.1; K08H10.1.2; 5K507; CE18875; NM_073174; WBGene00002263; WP:CE18875; lea WormBase description: The lea-1 gene encodes a protein that is predicted to be hydrophilic and heat-resistant, and that might participate in anhydrobiosis.
M116.2 M116.2 P W All gene names: M116.2; 4J165; CE33675; WBGene00019789; WP:CE33675 WormBase description: glycogenin glucosyltransferase
R74.3 R74.3 P W All gene names: xbp-1; R74.3; R74.3.1; R74.3.2; 3F285; CE01056; WBGene00006959; WP:CE01056 WormBase description: xbp-1 encodes a bZIP transcription factor orthologous to yeast Hac1 and mammalian X box-binding protein 1 (XBP-1, OMIM:194355); XBP-1 is required for the unfolded protein response (UPR) that counteracts cellular stress induced by accumulation of unfolded proteins in the endoplasmic reticulum (ER); XBP-1 mRNA is spliced by the IRE-1 endoribonuclease to promote translation of transcriptionally active XBP-1 that positively regulates UPR gene expression to maintain ER homeostasis and promote normal development. WormBase CDS description: X box DNA binding protein-1
T03E6.7 T03E6.7 P W All gene names: cpl-1; T03E6.7; T03E6.7.1; T03E6.7.2; 5R74; CE16333; NM_074798; O45734_CAEEL; WBGene00000776; WP:CE16333 WormBase description: cpl-1 encodes a member of the cathepsin L-like cysteine protease family required for embryonic viability and normal growth; expressed in eggshells and throughout early embryos, accumulates in intestinal cells during late embryogenesis, and expressed in the cuticle, gonad, and pharynx later in development. WormBase CDS description: cathepsin-like protease
T03G11.6 T03G11.6 P W All gene names: T03G11.6; CE04874; Q22123_CAEEL; WBGene00020199; WP:CE04874; XF796
T04D3.5 T04D3.5 P W All gene names: T04D3.5; 1N922; CE13161; WBGene00011434; WP:CE13161
T10C6.10 T10C6.10 P W All gene names: T10C6.10; 5Q517; CE16385; WBGene00011691; WP:CE16385 WormBase description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
T10C6.9 T10C6.9 P W All gene names: T10C6.9; 5Q514; WBGene00011690
Y4C6A.3 Y4C6A.3 P W All gene names: Y4C6A.3; 4G216; CE21299; WBGene00021153; WP:CE21299 WormBase description: zinc finger protein
Y62H9A.5 Y62H9A.5 P W All gene names: Y62H9A.5; CE31124; WBGene00013393; WP:CE31124; XM500
Y71H10A.1 Y71H10A.1 P W All gene names: Y71H10A.1; Y71H10A.1b.1; Y71H10A.1b.2; Y71H10A.1b.3; CE28266; CE37296; WBGene00022199; WP:CE28266; WP:CE37296; XD563 WormBase description: Y71H10A.1 is orthologous to the human gene PHOSPHOFRUCTOKINASE, MUSCLE TYPE (PFKM; OMIM:232800), which when mutated leads to glycogen storage disease VII.
ZC373.2 ZC373.2 P W All gene names: ZC373.2; CE02375; WBGene00013867; WP:CE02375; XK676
ZK546.15 ZK546.15 P W All gene names: try-1; ZK546.15; 2F238; CE36075; NM_062509; WBGene00006619; WP:CE36075 WormBase description: Plasminogen
ZK813.3 ZK813.3 P W All gene names: ZK813.3; CE29944; WBGene00022822; WP:CE29944; XE59